Gene: ERCC6

2074
ARMD5|CKN2|COFS|COFS1|CSB|CSB-PGBD3|POF11|RAD26|UVSS1
ERCC excision repair 6, chromatin remodeling factor
protein-coding
10q11.23
Ensembl:ENSG00000225830 MIM:609413 Vega:OTTHUMG00000018195 UniprotKB:Q03468
NG_009442.1
PubMed
0   ANCO-SNPs
ND
15   
4.943e-2 (AD)  9.617e-2 (ND)   (Frontal_Cortex)
4.479e-1 (AD)  5.617e-1 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
PRR14L0.89
MYO9A0.889
EPG50.882
ANKRD170.875
NSD10.866
ARID1B0.864
RALGAPB0.863
UGGT10.862
AKAP90.859
RPAP20.859

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
OR4F5-0.405
OR4F29-0.374
S100A1-0.374
COPZ2-0.37
RBP1-0.365
S100A14-0.359
AQP5-0.358
ENDOU-0.356
PINLYP-0.355
APOM-0.341

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C1111182',3,3',4',5-pentachloro-4-hydroxybiphenyl"2',3,3',4',5-pentachloro-4-hydroxybiphenyl results in decreased expression of ERCC6 mRNA"19114083
C0235142,6-dinitrotoluene"2,6-dinitrotoluene affects the expression of ERCC6 mRNA"21346803
C0251603-aminobenzamide3-aminobenzamide inhibits the reaction [ERCC6 gene mutant form results in increased abundance of Superoxides]25440059
C0251603-aminobenzamideERCC6 gene mutant form affects the susceptibility to 3-aminobenzamide25440059
C0251603-aminobenzamide3-aminobenzamide affects the localization of ERCC6 protein25440059
C5505476-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide"6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [3-Hydroxybutyric Acid inhibits the reaction [ERCC6 gene mutant form results in increased abundance of Superoxides]]"25440059
D000105Acetyl Coenzyme A3-Hydroxybutyric Acid inhibits the reaction [ERCC6 gene mutant form results in decreased abundance of Acetyl Coenzyme A]25440059
D000105Acetyl Coenzyme AERCC6 gene mutant form results in decreased abundance of Acetyl Coenzyme A25440059
D000105Acetyl Coenzyme A"N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [ERCC6 gene mutant form results in decreased abundance of Acetyl Coenzyme A]"25440059
C079422acylfulveneERCC6 mutant form results in increased susceptibility to acylfulvene28076683
C079422acylfulveneERCC6 mutant form results in increased susceptibility to acylfulvene analog28076683
C079422acylfulveneERCC6 protein affects the reaction [PTGR1 protein results in increased susceptibility to acylfulvene]28076683
D000249Adenosine MonophosphateERCC6 gene mutant form results in increased abundance of Adenosine Monophosphate25440059
D000255Adenosine TriphosphateERCC6 gene mutant form results in decreased abundance of Adenosine Triphosphate25440059
D000255Adenosine Triphosphatenicotinamide-beta-riboside inhibits the reaction [ERCC6 gene mutant form results in decreased abundance of Adenosine Triphosphate]25440059
D016604Aflatoxin B1Aflatoxin B1 results in increased methylation of ERCC6 gene27153756
D018501Antirheumatic AgentsAntirheumatic Agents results in increased expression of ERCC6 mRNA24449571
D001151ArsenicArsenic affects the expression of ERCC621235219
C006632arsenic trioxideERCC6 protein affects the susceptibility to arsenic trioxide22280988
C043372ascaridoleERCC6 protein affects the susceptibility to ascaridole22280988
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of ERCC6 mRNA20064835|2846112
C072553benzyloxycarbonylleucyl-leucyl-leucine aldehydebenzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [ERCC6 gene mutant form results in decreased expression of SIRT1 protein]25440059
D004958EstradiolEstradiol results in increased expression of ERCC6 mRNA22082530
C006780bisphenol Abisphenol A results in increased expression of ERCC6 mRNA25181051
C006780bisphenol Abisphenol A results in increased methylation of ERCC6 gene28505145
D019256Cadmium ChlorideCadmium Chloride results in decreased methylation of ERCC6 promoter22457795
D002227CarbazolesERCC6 protein affects the susceptibility to Carbazoles22280988
D000068579CelecoxibCelecoxib results in decreased expression of ERCC6 mRNA28201806
D002794Choline[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of ERCC6 gene20938992
D019343Citric AcidERCC6 gene mutant form results in decreased abundance of Citric Acid25440059
D009243NAD"ERCC6 gene mutant form promotes the reaction [N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride results in increased abundance of NAD]"25440059
D009243NADERCC6 gene mutant form results in increased metabolism of NAD25440059
D009243NADERCC6 inhibits the reaction [NAD results in increased activity of PARP1 protein]25440059
D009243NADNAD results in increased ADP-ribosylation of ERCC6 protein25440059
D009243NADERCC6 gene mutant form results in decreased abundance of NAD25440059
D009243NADnicotinamide-beta-riboside inhibits the reaction [ERCC6 gene mutant form results in decreased abundance of NAD]25440059
D019327Copper SulfateCopper Sulfate results in decreased expression of ERCC6 mRNA19549813
C017160cypermethrincypermethrin results in increased expression of ERCC6 mRNA21142847
C014347decitabinedecitabine results in increased expression of ERCC6 mRNA22082530
D003671DEET[Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of ERCC6 mRNA28659758
D002945CisplatinERCC6 protein inhibits the reaction [Cisplatin results in increased activity of ATR protein]21324906
D002945CisplatinERCC6 protein inhibits the reaction [Cisplatin results in increased activity of CHEK1 protein]21324906
D002945CisplatinERCC6 protein inhibits the reaction [Cisplatin results in increased activity of CHEK2 protein]21324906
D002945CisplatinERCC6 protein inhibits the reaction [Cisplatin results in increased phosphorylation of H2AFX protein]21324906
D002945CisplatinERCC6 protein mutant form results in increased susceptibility to Cisplatin21324906
D002945CisplatinCisplatin results in decreased expression of ERCC6 mRNA24865317
D002945CisplatinERCC6 protein results in decreased susceptibility to Cisplatin21324906
D002945CisplatinCisplatin results in decreased expression of ERCC6 mRNA26739623
D004041Dietary FatsDietary Fats inhibits the reaction [ERCC6 gene mutant form results in decreased abundance of 3-Hydroxybutyric Acid]25440059
D004041Dietary FatsDietary Fats inhibits the reaction [ERCC6 gene mutant form results in decreased expression of BCL2L1 protein]25440059
D004041Dietary FatsDietary Fats inhibits the reaction [ERCC6 gene mutant form results in decreased expression of BCL2 protein]25440059
D004041Dietary FatsDietary Fats inhibits the reaction [ERCC6 gene mutant form results in decreased expression of SIRT1 protein]25440059
D004041Dietary FatsDietary Fats inhibits the reaction [ERCC6 gene mutant form results in increased abundance of Poly Adenosine Diphosphate Ribose]25440059
D004041Dietary FatsDietary Fats inhibits the reaction [ERCC6 gene mutant form results in increased acetylation of RELA protein]25440059
D004041Dietary FatsDietary Fats inhibits the reaction [ERCC6 gene mutant form results in increased acetylation of TRP53 protein]25440059
D004041Dietary FatsDietary Fats inhibits the reaction [ERCC6 gene mutant form results in increased expression of BAX protein]25440059
D004051Diethylhexyl PhthalateERCC6 gene mutant form results in increased susceptibility to Diethylhexyl Phthalate15340056
D000431Ethanol[BRCA1 protein affects the expression of ERCC6 mRNA] which affects the susceptibility to Ethanol26629949
D005485FlutamideFlutamide results in increased expression of ERCC6 mRNA24136188
D005492Folic Acid[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of ERCC6 gene20938992
D005557FormaldehydeFormaldehyde results in decreased expression of ERCC6 mRNA20655997
D019833GenisteinGenistein results in increased expression of ERCC6 protein24552547
C004312glycidolglycidol results in increased expression of ERCC6 mRNA24915197
D006861Hydrogen PeroxideHydrogen Peroxide results in increased expression of ERCC6 mRNA26846883
D006861Hydrogen PeroxideERCC6 protein affects the susceptibility to Hydrogen Peroxide25136123
D006861Hydrogen Peroxide[ERCC6 protein affects the susceptibility to Hydrogen Peroxide] which affects the expression of H2AFX protein25136123
D0201553-Hydroxybutyric Acid3-Hydroxybutyric Acid inhibits the reaction [ERCC6 gene mutant form results in decreased abundance of Acetyl Coenzyme A]25440059
D0201553-Hydroxybutyric Acid3-Hydroxybutyric Acid inhibits the reaction [ERCC6 gene mutant form results in decreased expression of SIRT1 protein]25440059
D0201553-Hydroxybutyric Acid3-Hydroxybutyric Acid inhibits the reaction [ERCC6 gene mutant form results in decreased expression of UCP2 protein]25440059
D0201553-Hydroxybutyric Acid3-Hydroxybutyric Acid inhibits the reaction [ERCC6 gene mutant form results in increased abundance of Superoxides]25440059
D0201553-Hydroxybutyric Acid3-Hydroxybutyric Acid inhibits the reaction [ERCC6 gene mutant form results in increased acetylation of TP53 protein]25440059
D0201553-Hydroxybutyric Acid"6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [3-Hydroxybutyric Acid inhibits the reaction [ERCC6 gene mutant form results in increased abundance of Superoxides]]"25440059
D0201553-Hydroxybutyric AcidDietary Fats inhibits the reaction [ERCC6 gene mutant form results in decreased abundance of 3-Hydroxybutyric Acid]25440059
D0201553-Hydroxybutyric AcidERCC6 gene mutant form results in decreased abundance of 3-Hydroxybutyric Acid25440059
D007052IbuprofenIbuprofen results in decreased expression of ERCC6 mRNA28201806
C008105illudin SERCC6 mutant form results in increased susceptibility to illudin S28076683
D015759Ionomycin[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of ERCC6 mRNA25613284
C102714irofulvenERCC6 mutant form results in increased susceptibility to irofulven28076683
C561695(+)-JQ1 compound(+)-JQ1 compound results in increased expression of ERCC6 mRNA24796395
C411319kurarinoneERCC6 protein affects the susceptibility to kurarinone22280988
D019344Lactic AcidERCC6 gene mutant form results in increased abundance of Lactic Acid25440059
D008148LovastatinLovastatin results in increased expression of ERCC6 mRNA26739623
D014975LuteinLutein results in decreased expression of ERCC6 mRNA24865317
D008694Methamphetamine[BRCA1 protein affects the expression of ERCC6 mRNA] which affects the susceptibility to Methamphetamine26629949
D008715Methionine[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of ERCC6 gene20938992
D008748MethylcholanthreneMethylcholanthrene promotes the reaction [AHR protein binds to ERCC6 promoter]20348232
D008741Methyl MethanesulfonateMethyl Methanesulfonate results in increased expression of ERCC6 mRNA26011545
C018613nicotinamide-beta-ribosidenicotinamide-beta-riboside inhibits the reaction [ERCC6 gene mutant form results in decreased abundance of Adenosine Triphosphate]25440059
C018613nicotinamide-beta-ribosidenicotinamide-beta-riboside inhibits the reaction [ERCC6 gene mutant form results in decreased abundance of NAD]25440059
D009537Nicotinamide MononucleotideERCC6 gene mutant form results in decreased abundance of Nicotinamide Mononucleotide25440059
C572712norkurarinolERCC6 protein affects the susceptibility to norkurarinol22280988
C434926N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride"ERCC6 gene mutant form affects the susceptibility to N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride"25440059
C434926N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride"ERCC6 gene mutant form promotes the reaction [N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride results in decreased abundance of Niacinamide]"25440059
C434926N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride"ERCC6 gene mutant form promotes the reaction [N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride results in increased abundance of NAD]"25440059
C434926N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride"N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [ERCC6 gene mutant form results in decreased abundance of Acetyl Coenzyme A]"25440059
C434926N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride"N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [ERCC6 gene mutant form results in increased abundance of Superoxides]"25440059
C434926N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride"N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride affects the localization of ERCC6 protein"25440059
C115774NU 1025ERCC6 gene mutant form affects the susceptibility to NU 102525440059
C115774NU 1025NU 1025 inhibits the reaction [ERCC6 gene mutant form results in increased abundance of Superoxides]25440059
C030110oxaliplatinERCC6 protein affects the susceptibility to oxaliplatin16773204
D010126OzoneERCC6 gene mutant form promotes the reaction [Ozone results in increased expression of CXCL2 protein]17095637
D010126OzoneERCC6 gene mutant form promotes the reaction [Ozone results in increased expression of TNF protein]17095637
D010269ParaquatERCC6 gene mutant form results in increased susceptibility to Paraquat12509265|1534005
D026023Permethrin[Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of ERCC6 mRNA28659758
D017671Platinum CompoundsERCC6 affects the susceptibility to Platinum Compounds21844884
D011064Poly Adenosine Diphosphate RiboseERCC6 gene mutant form results in increased abundance of Poly Adenosine Diphosphate Ribose25440059
D011064Poly Adenosine Diphosphate RiboseDietary Fats inhibits the reaction [ERCC6 gene mutant form results in increased abundance of Poly Adenosine Diphosphate Ribose]25440059
D011064Poly Adenosine Diphosphate Riboseresveratrol inhibits the reaction [ERCC6 gene mutant form results in increased abundance of Poly Adenosine Diphosphate Ribose]25440059
C019536potassium bromateERCC6 protein affects the susceptibility to potassium bromate25136123
C019536potassium bromateveliparib promotes the reaction [ERCC6 protein affects the susceptibility to potassium bromate]25136123
D011192Potassium DichromatePotassium Dichromate results in decreased expression of ERCC6 mRNA23608068
D011729Pyridostigmine Bromide[Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of ERCC6 mRNA28659758
C059514resveratrolresveratrol inhibits the reaction [ERCC6 gene mutant form results in decreased expression of BCL2L1 protein]25440059
C059514resveratrolresveratrol inhibits the reaction [ERCC6 gene mutant form results in decreased expression of BCL2 protein]25440059
C059514resveratrolresveratrol inhibits the reaction [ERCC6 gene mutant form results in decreased expression of SIRT1 protein]25440059
C059514resveratrolresveratrol inhibits the reaction [ERCC6 gene mutant form results in increased abundance of Poly Adenosine Diphosphate Ribose]25440059
C059514resveratrolresveratrol inhibits the reaction [ERCC6 gene mutant form results in increased acetylation of RELA protein]25440059
C059514resveratrolresveratrol inhibits the reaction [ERCC6 gene mutant form results in increased acetylation of TRP53 protein]25440059
C059514resveratrolresveratrol inhibits the reaction [ERCC6 gene mutant form results in increased expression of BAX protein]25440059
D012402RotenoneERCC6 protein affects the susceptibility to Rotenone25136123
D012834SilverSilver results in increased expression of ERCC6 mRNA19429238
C017947sodium arsenitesodium arsenite results in decreased expression of ERCC6 mRNA17558810
D019802Succinic AcidERCC6 gene mutant form results in increased abundance of Succinic Acid25440059
D013481Superoxides3-aminobenzamide inhibits the reaction [ERCC6 gene mutant form results in increased abundance of Superoxides]25440059
D013481Superoxides3-Hydroxybutyric Acid inhibits the reaction [ERCC6 gene mutant form results in increased abundance of Superoxides]25440059
D013481Superoxides"6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [3-Hydroxybutyric Acid inhibits the reaction [ERCC6 gene mutant form results in increased abundance of Superoxides]]"25440059
D013481SuperoxidesERCC6 gene mutant form results in increased abundance of Superoxides25440059
D013481SuperoxidesERCC6 protein results in decreased abundance of Superoxides25440059
D013481Superoxides"N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [ERCC6 gene mutant form results in increased abundance of Superoxides]"25440059
D013481SuperoxidesNU 1025 inhibits the reaction [ERCC6 gene mutant form results in increased abundance of Superoxides]25440059
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of ERCC6 mRNA20106945
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased expression of ERCC6 mRNA21215274
D013755Tetradecanoylphorbol Acetate[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of ERCC6 mRNA25613284
D014520UrethaneUrethane results in increased expression of ERCC6 mRNA28818685
D014635Valproic AcidValproic Acid results in decreased methylation of ERCC6 gene29154799
C521013veliparibveliparib promotes the reaction [ERCC6 protein affects the susceptibility to potassium bromate]25136123
D009536Niacinamide"ERCC6 gene mutant form promotes the reaction [N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride results in decreased abundance of Niacinamide]"25440059
D009536NiacinamideERCC6 gene mutant form results in increased abundance of Niacinamide25440059

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0003677DNA binding-IDA8999876  12560492  16107709  
GO:0003678DNA helicase activityNOTIDA8999876  
GO:0003682chromatin binding-IDA16916636  
GO:0005515protein binding-IPI7663514  7664335  8999876  10944529  16107709  22466612  
GO:0005524ATP binding-IDA12560492  16107709  
GO:0008022protein C-terminus binding-IPI16246722  
GO:0008094DNA-dependent ATPase activity-IDA8999876  12560492  16107709  
GO:0030296protein tyrosine kinase activator activity-IDA17626041  
GO:0044877protein-containing complex binding-IDA16916636  
GO:0047485protein N-terminus binding-IPI7664335  
GO ID GO Term Qualifier Evidence PubMed
GO:0000303response to superoxide-IEA-  
GO:0006283transcription-coupled nucleotide-excision repair-IMP10564257  16916636  
GO:0006283transcription-coupled nucleotide-excision repair-TAS-  
GO:0006284base-excision repair-IMP9973627  
GO:0006290pyrimidine dimer repair-IEA-  
GO:0006362transcription elongation from RNA polymerase I promoter-IEA-  
GO:0006366transcription by RNA polymerase II-NAS7664335  
GO:0006979response to oxidative stress-IDA16107709  
GO:0006979response to oxidative stress-IGI17626041  
GO:0007256activation of JNKK activity-IEA-  
GO:0007257activation of JUN kinase activity-IEA-  
GO:0008630intrinsic apoptotic signaling pathway in response to DNA damage-IEA-  
GO:0009411response to UV-IDA16916636  
GO:0009636response to toxic substance-IEA-  
GO:0010165response to X-ray-IEA-  
GO:0010224response to UV-B-IEA-  
GO:0010332response to gamma radiation-IEA-  
GO:0032784regulation of DNA-templated transcription, elongation-IDA9326587  
GO:0032786positive regulation of DNA-templated transcription, elongation-IDA9326587  
GO:0035264multicellular organism growth-IEA-  
GO:0045494photoreceptor cell maintenance-IEA-  
GO:0045815positive regulation of gene expression, epigenetic-TAS-  
GO:0061098positive regulation of protein tyrosine kinase activity-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO:0005634nucleus-IDA12560492  17626041  
GO:0005634nucleus-IEA-  
GO:0005654nucleoplasm-IDA16107709  
GO:0005654nucleoplasm-TAS-  
GO:0005730nucleolus-IDA16107709  17626041  
GO:0008023transcription elongation factor complex-IDA9326587  
KEGG ID KEGG Term
hsa03420Nucleotide excision repair
Reactome ID Reactome Term Evidence
R-HSA-212165Epigenetic regulation of gene expressionIEA
R-HSA-212165Epigenetic regulation of gene expressionTAS
R-HSA-427389ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expressionIEA
R-HSA-5250913Positive epigenetic regulation of rRNA expressionIEA
R-HSA-5250913Positive epigenetic regulation of rRNA expressionTAS
R-HSA-5250924B-WICH complex positively regulates rRNA expressionTAS
R-HSA-5696398Nucleotide Excision RepairTAS
R-HSA-6781823Formation of TC-NER Pre-Incision ComplexTAS
R-HSA-6781827Transcription-Coupled Nucleotide Excision Repair (TC-NER)TAS
R-HSA-6782135Dual incision in TC-NERTAS
R-HSA-6782210Gap-filling DNA repair synthesis and ligation in TC-NERTAS
R-HSA-73762RNA Polymerase I Transcription InitiationTAS
R-HSA-73854RNA Polymerase I Promoter ClearanceTAS
R-HSA-73864RNA Polymerase I TranscriptionTAS
R-HSA-73894DNA RepairTAS
R-HSA-74160Gene expression (Transcription)IEA
R-HSA-74160Gene expression (Transcription)TAS

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
19444904Laryngeal cancer risk associated with smoking and alcohol consumption is modified by genetic polymorphisms in ERCC5, ERCC6 and RAD23B but not by polymorphisms in five other nucleotide excision repair genes. (2009 Sep 15)Abbasi RInt J Cancer
10910954Reduced expression levels of nucleotide excision repair genes in lung cancer: a case-control analysis. (2000 Aug)Cheng LCarcinogenesis
17933579A novel single nucleotide polymorphism in ERCC6 gene is associated with oral cancer susceptibility in Taiwanese patients. (2008 Jun)Chiu CFOral Oncol
16537713Genetic variation in the nucleotide excision repair pathway and bladder cancer risk. (2006 Mar)Garcia-Closas MCancer Epidemiol Biomarkers Prev
17728339High-order interactions among genetic polymorphisms in nucleotide excision repair pathway genes and smoking in modulating bladder cancer risk. (2007 Oct)Chen MCarcinogenesis
18789574ERCC6/CSB gene polymorphisms and lung cancer risk. (2009 Jan 8)Ma HCancer Lett
18026184NAT2 and NER genetic variants and sporadic prostate cancer susceptibility in African Americans. (2008)Hooker SProstate Cancer Prostatic Dis
16399771Polymorphisms in nucleotide excision repair genes, smoking and breast cancer in African Americans and whites: a population-based case-control study. (2006 Jul)Mechanic LECarcinogenesis
16492920Nucleotide excision repair gene polymorphisms and risk of advanced colorectal adenoma: XPC polymorphisms modify smoking-related risk. (2006 Feb)Huang WYCancer Epidemiol Biomarkers Prev
17575242Nucleotide excision repair pathway genes and oral premalignant lesions. (2007 Jun 15)Wang YClin Cancer Res
27791261Meta-analysis reveals no significant association between ERCC6 polymorphisms and bladder cancer risk. (2017 Mar 2)Hong ZInt J Biol Markers
24924712[Study on gene-gene, gene-environmental interactions of DNA repair genes related with age-related cataract]. (2014 Apr 22)Yang MZhonghua Yi Xue Za Zhi
11900225Expression of nucleotide excision repair genes and the risk for squamous cell carcinoma of the head and neck. (2002 Jan 15)Cheng LCancer
25089939Polymorphism of DNA repair genes OGG1, XRCC1, XPD and ERCC6 in bladder cancer in Belarus. (2014 Sep)Ramaniuk VPBiomarkers
17854076A variant of the Cockayne syndrome B gene ERCC6 confers risk of lung cancer. (2008 Jan)Lin ZHum Mutat