Gene info: ID 2100

Gene: ESR2

GENE ID: 2100

Description: estrogen receptor 2

Gene type: protein-coding

Location: 14q23.2-q23.3

dbXrefs: Ensembl:ENSG00000140009 MIM:601663 Vega:OTTHUMG00000141306 UniprotKB:Q92731

RefSeq: NG_011535.1

Retrived from: PubMed

SNPs: 1 ANCO-SNPs

Phenotype: ND

# Publications: 12

Sherlock p-value : NA (AD) NA (ND) (Frontal_Cortex)

Pascal p-value : 8.454e-1 (AD) 7.784e-1 (ND)

ANCO-SNPs

SNP ID	Position	Alleles	Trait	Variation Type
rs2297301	chr14:64177487 (GRCh38.p7)	T>C	nicotine dependence	SNV(Single Nucleotide Variation)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol	Pearson Correlation Coefficient
ACTA2-AS1	0.604
OVCH1	0.601
NFAT5	0.591
PHC3	0.587
SHPRH	0.587
BTAF1	0.578
ESR1	0.578
NRP2	0.572
HEATR1	0.569
LAMA3	0.569

Top 10 negatively co-expressed genes

Gene Symbol	Pearson Correlation Coefficient
TMEM253	-0.386
HES6	-0.385
CLDND2	-0.363
BTBD17	-0.362
HHATL	-0.356
NEU4	-0.351
NANOS3	-0.35
FAM69C	-0.336
LHPP	-0.331
S100A1	-0.331

ID	Drug Name	Drug Type	CAS Num	Status	Role
DB00255	Diethylstilbestrol	Small Molecule	56-53-1	Approved\|Investigational	Target
DB00481	Raloxifene	Small Molecule	84449-90-1	Approved\|Investigational	Target
DB00655	Estrone	Small Molecule	53-16-7	Approved	Target
DB00675	Tamoxifen	Small Molecule	10540-29-1	Approved	Target
DB00783	Estradiol	Small Molecule	50-28-2	Approved\|Investigational	Target
DB01108	Trilostane	Small Molecule	13647-35-3	Approved\|Investigational\|Withdrawn	Target
DB01196	Estramustine	Small Molecule	2998-57-4	Approved\|Investigational	Target
DB01428	Oxybenzone	Small Molecule	131-57-7	Approved	Target
DB01645	Genistein	Small Molecule	446-72-0	Investigational	Target
DB01708	Prasterone	Small Molecule	53-43-0	Approved\|Investigational\|Nutraceutical	Target
DB01878	Benzophenone	Small Molecule	119-61-9	Approved	Target
DB02746	Phthalic Acid	Small Molecule	88-99-3	Experimental	Target
DB02757	Pyrazole	Small Molecule	288-13-1	Experimental	Target
DB02983	Para-Mercury-Benzenesulfonic Acid	Small Molecule		Experimental	Target
DB03467	Naringenin	Small Molecule	480-41-1	Experimental	Target
DB03860	N-Butyl-11-[(7r,8r,9s,13s,14s,17s)-3,17-Dihydroxy-13-Methyl-7,8,9,11,12,13,14,15,16,17-Decahydro-6h-Cyclopenta[a]Phenanthren-7-Yl]-N-Methylundecanamide	Small Molecule		Experimental	Target
DB03882	5-Alpha-Androstane-3-Beta,17beta-Diol	Small Molecule	571-20-0	Experimental	Target
DB04020	4-(2-{[4-{[3-(4-Chlorophenyl)Propyl]Sulfanyl}-6-(1-Piperazinyl)-1,3,5-Triazin-2-Yl]Amino}Ethyl)Phenol	Small Molecule		Experimental	Target
DB04216	Quercetin	Small Molecule	117-39-5	Experimental\|Investigational	Target
DB04468	Afimoxifene	Small Molecule	68392-35-8	Investigational	Target
DB04573	Estriol	Small Molecule	50-27-1	Approved\|Investigational	Target
DB04574	Estrone sulfate	Small Molecule	481-97-0	Approved	Target
DB05052	MF101	Small Molecule	-	Investigational	Target
DB05882	CHF 4227	Small Molecule	-	Investigational	Target
DB05966	TAS-108	Small Molecule	229634-97-3	Investigational	Target
DB06202	Lasofoxifene	Small Molecule	180916-16-9	Approved\|Investigational	Target
DB06249	Arzoxifene	Small Molecule	182133-25-1	Approved\|Investigational	Target
DB06401	Bazedoxifene	Small Molecule	198481-32-2	Approved\|Investigational	Target
DB06832	2-(3-FLUORO-4-HYDROXYPHENYL)-7-VINYL-1,3-BENZOXAZOL-5-OL	Small Molecule		Experimental	Target
DB06875	3-(3-FLUORO-4-HYDROXYPHENYL)-7-HYDROXY-1-NAPHTHONITRILE	Small Molecule		Experimental	Target
DB06927	[5-HYDROXY-2-(4-HYDROXYPHENYL)-1-BENZOFURAN-7-YL]ACETONITRILE	Small Molecule		Experimental	Target
DB06937	4-(6-HYDROXY-BENZO[D]ISOXAZOL-3-YL)BENZENE-1,3-DIOL	Small Molecule		Experimental	Target
DB07009	2-(5-HYDROXY-NAPHTHALEN-1-YL)-1,3-BENZOOXAZOL-6-OL	Small Molecule		Experimental	Target
DB07032	2-(4-HYDROXY-PHENYL)BENZOFURAN-5-OL	Small Molecule		Experimental	Target
DB07036	(3aS,4R,9bR)-2,2-difluoro-4-(4-hydroxyphenyl)-6-(methoxymethyl)-1,2,3,3a,4,9b-hexahydrocyclopenta[c]chromen-8-ol	Small Molecule		Experimental	Target
DB07119	1-CHLORO-6-(4-HYDROXYPHENYL)-2-NAPHTHOL	Small Molecule		Experimental	Target
DB07150	4-(4-HYDROXYPHENYL)-1-NAPHTHALDEHYDE OXIME	Small Molecule		Experimental	Target
DB07198	5-HYDROXY-2-(4-HYDROXYPHENYL)-1-BENZOFURAN-7-CARBONITRILE	Small Molecule		Experimental	Target
DB07230	3-BROMO-6-HYDROXY-2-(4-HYDROXYPHENYL)-1H-INDEN-1-ONE	Small Molecule		Experimental	Target
DB07236	3-(6-HYDROXY-NAPHTHALEN-2-YL)-BENZO[D]ISOOXAZOL-6-OL	Small Molecule		Experimental	Target
DB07638	(3AS,4R,9BR)-2,2-DIFLUORO-4-(4-HYDROXYPHENYL)-1,2,3,3A,4,9B-HEXAHYDROCYCLOPENTA[C]CHROMEN-8-OL	Small Molecule		Experimental	Target
DB07702	(16ALPHA,17ALPHA)-ESTRA-1,3,5(10)-TRIENE-3,16,17-TRIOL	Small Molecule		Experimental	Target
DB07757	(9aS)-4-bromo-9a-butyl-7-hydroxy-1,2,9,9a-tetrahydro-3H-fluoren-3-one	Small Molecule		Experimental	Target
DB07933	Erteberel	Small Molecule	533884-09-2	Experimental\|Investigational	Target
DB08020	(3AS,4R,9BR)-4-(4-HYDROXYPHENYL)-6-(METHOXYMETHYL)-1,2,3,3A,4,9B-HEXAHYDROCYCLOPENTA[C]CHROMEN-8-OL	Small Molecule		Experimental	Target
DB09086	Eugenol	Small Molecule	97-53-0	Approved	Target
DB09535	Octocrylene	Small Molecule		Approved\|Investigational	Target
DB11219	Enzacamene	Small Molecule	36861-47-9	Approved	Target
DB11674	Equol	Small Molecule	531-95-3	Investigational	Target
DB13869	2-Methoxy-6-{(E)-[(4-methylphenyl)imino]methyl}phenol	Small Molecule	20772-64-9	Experimental	Target
DB13952	Estradiol acetate	Small Molecule	4245-41-4	Approved\|Investigational	Target
DB13953	Estradiol benzoate	Small Molecule	50-50-0	Approved\|Investigational	Target
DB13954	Estradiol cypionate	Small Molecule	313-06-4	Approved\|Investigational	Target
DB13955	Estradiol dienanthate	Small Molecule	7732-97-0	Approved\|Investigational	Target
DB13956	Estradiol valerate	Small Molecule	979-32-8	Approved\|Investigational	Target

ID	Drug Name	Action	PubMed
C540596	1,2,5,6-tetrabromocyclooctane	"1,2,5,6-tetrabromocyclooctane results in decreased expression of ESR2 mRNA"	25646719
C517232	1,2-dibromo-4-(1,2-dibromoethyl)cyclohexane	"1,2-dibromo-4-(1,2-dibromoethyl)cyclohexane binds to ESR2 protein"	24375616
C562246	1-(4-nitro-2-(trifluoromethyl)phenyl)-4-(3-(trifluoromethyl)phenyl)piperazine	1-(4-nitro-2-(trifluoromethyl)phenyl)-4-(3-(trifluoromethyl)phenyl)piperazine results in increased expression of ESR2 mRNA	21128595
C024871	16 alpha-iodoestradiol	16 alpha-iodoestradiol binds to ESR2 protein	9048584
C024871	16 alpha-iodoestradiol	2-hydroxyestradiol inhibits the reaction [16 alpha-iodoestradiol binds to ESR2 protein]	9048584
C024871	16 alpha-iodoestradiol	4-hydroxyestradiol inhibits the reaction [16 alpha-iodoestradiol binds to ESR2 protein]	9048584
C024871	16 alpha-iodoestradiol	afimoxifene inhibits the reaction [16 alpha-iodoestradiol binds to ESR2 protein]	9048584
C024871	16 alpha-iodoestradiol	Androstenediol inhibits the reaction [16 alpha-iodoestradiol binds to ESR2 protein]	9048584
C024871	16 alpha-iodoestradiol	Clomiphene inhibits the reaction [16 alpha-iodoestradiol binds to ESR2 protein]	9048584
C024871	16 alpha-iodoestradiol	Coumestrol inhibits the reaction [16 alpha-iodoestradiol binds to ESR2 protein]	9048584
C024871	16 alpha-iodoestradiol	Dienestrol inhibits the reaction [16 alpha-iodoestradiol binds to ESR2 protein]	9048584
C024871	16 alpha-iodoestradiol	Diethylstilbestrol inhibits the reaction [16 alpha-iodoestradiol binds to ESR2 protein]	9048584
C024871	16 alpha-iodoestradiol	Estradiol inhibits the reaction [16 alpha-iodoestradiol binds to ESR2 protein]	9048584
C024871	16 alpha-iodoestradiol	Estriol inhibits the reaction [16 alpha-iodoestradiol binds to ESR2 protein]	9048584
C024871	16 alpha-iodoestradiol	Estrone inhibits the reaction [16 alpha-iodoestradiol binds to ESR2 protein]	9048584
C024871	16 alpha-iodoestradiol	fulvestrant inhibits the reaction [16 alpha-iodoestradiol binds to ESR2 protein]	9048584
C024871	16 alpha-iodoestradiol	Genistein inhibits the reaction [16 alpha-iodoestradiol binds to ESR2 protein]	9048584
C024871	16 alpha-iodoestradiol	Hexestrol inhibits the reaction [16 alpha-iodoestradiol binds to ESR2 protein]	9048584
C024871	16 alpha-iodoestradiol	moxestrol inhibits the reaction [16 alpha-iodoestradiol binds to ESR2 protein]	9048584
C024871	16 alpha-iodoestradiol	Nafoxidine inhibits the reaction [16 alpha-iodoestradiol binds to ESR2 protein]	9048584
C024871	16 alpha-iodoestradiol	Tamoxifen inhibits the reaction [16 alpha-iodoestradiol binds to ESR2 protein]	9048584
C002591	16-ketoestrone	16-ketoestrone binds to ESR2 protein	16728493
C118559	1-bromopropane	1-bromopropane results in increased expression of ESR2 protein alternative form	27634370
C033729	1H,1H,2H,2H-perfluorodecanol	"1H,1H,2H,2H-perfluorodecanol promotes the reaction [ESR2 protein binds to NCOA2 protein]"	17603182
C033729	1H,1H,2H,2H-perfluorodecanol	"1H,1H,2H,2H-perfluorodecanol results in increased activity of ESR2 protein"	17603182
C508406	1H,1H,2H,2H-perfluorooctan-1-ol	"1H,1H,2H,2H-perfluorooctan-1-ol promotes the reaction [ESR2 protein binds to NCOA2 protein]"	17603182
C508406	1H,1H,2H,2H-perfluorooctan-1-ol	"1H,1H,2H,2H-perfluorooctan-1-ol results in increased activity of ESR2 protein"	17603182
C033146	1-hydroxypyrene	1-hydroxypyrene inhibits the reaction [ESR2 protein binds to Estradiol]	22989670
C033146	1-hydroxypyrene	ESR2 protein binds to 1-hydroxypyrene	22989670
C033146	1-hydroxypyrene	1-hydroxypyrene promotes the reaction [ESR2 protein binds to ESR2 protein]	22989670
C033146	1-hydroxypyrene	1-hydroxypyrene results in increased activity of ESR2 protein	22989670
C033146	1-hydroxypyrene	fulvestrant inhibits the reaction [1-hydroxypyrene results in increased activity of ESR2 protein]	22989670
C029350	1-naphthol	1-naphthol inhibits the reaction [ESR2 protein binds to Estradiol]	22989670
C029350	1-naphthol	ESR2 protein binds to 1-naphthol	22989670
C029350	1-naphthol	1-naphthol results in increased activity of ESR2 protein	22989670
C029350	1-naphthol	fulvestrant inhibits the reaction [1-naphthol results in increased activity of ESR2 protein]	22989670
C054919	2,2-(2-chlorophenyl-4'-chlorophenyl)-1,1-dichloroethene	"2,2-(2-chlorophenyl-4'-chlorophenyl)-1,1-dichloroethene results in increased expression of ESR2 mRNA"	26372180
C054919	2,2-(2-chlorophenyl-4'-chlorophenyl)-1,1-dichloroethene	"2,2-(2-chlorophenyl-4'-chlorophenyl)-1,1-dichloroethene results in increased expression of ESR2 mRNA"	19101654
C054919	2,2-(2-chlorophenyl-4'-chlorophenyl)-1,1-dichloroethene	"2,2-(2-chlorophenyl-4'-chlorophenyl)-1,1-dichloroethene results in decreased expression of ESR2 protein"	18195494
C005849	2,2,2-trichloroethanol	"2,2,2-trichloroethanol binds to ESR2 protein"	12224631
C477694	2,2',4,4',5-brominated diphenyl ether	"2,2',4,4',5-brominated diphenyl ether inhibits the reaction [Estradiol results in increased activity of ESR2 protein]"	19672399
C511295	2,2',4,4'-tetrabromodiphenyl ether	"2,2',4,4'-tetrabromodiphenyl ether results in increased expression of ESR2 protein"	26988655
C511295	2,2',4,4'-tetrabromodiphenyl ether	"fulvestrant inhibits the reaction [2,2',4,4'-tetrabromodiphenyl ether results in increased expression of ESR2 protein]"	26988655
C511295	2,2',4,4'-tetrabromodiphenyl ether	"2,2',4,4'-tetrabromodiphenyl ether metabolite results in increased expression of ESR2 mRNA"	24956591
C511295	2,2',4,4'-tetrabromodiphenyl ether	"2,2',4,4'-tetrabromodiphenyl ether metabolite results in increased expression of ESR2 protein"	24956591
C511295	2,2',4,4'-tetrabromodiphenyl ether	"2,2',4,4'-tetrabromodiphenyl ether results in decreased expression of ESR2 mRNA"	24956591
C511295	2,2',4,4'-tetrabromodiphenyl ether	"2,2',4,4'-tetrabromodiphenyl ether results in decreased expression of ESR2 protein"	24956591
C035476	2,2',4,4'-tetrahydroxybenzophenone	"2,2',4,4'-tetrahydroxybenzophenone binds to and results in increased activity of ESR2 protein"	16079615
C035476	2,2',4,4'-tetrahydroxybenzophenone	"2,2',4,4'-tetrahydroxybenzophenone binds to ESR2 protein"	19913605
C035476	2,2',4,4'-tetrahydroxybenzophenone	"2,2',4,4'-tetrahydroxybenzophenone results in increased activity of ESR2 protein"	25106122
C035476	2,2',4,4'-tetrahydroxybenzophenone	"2,2',4,4'-tetrahydroxybenzophenone binds to and results in increased activity of ESR2 protein"	15458795
C035476	2,2',4,4'-tetrahydroxybenzophenone	"2,2',4,4'-tetrahydroxybenzophenone results in decreased expression of ESR2 mRNA"	15458795
C035476	2,2',4,4'-tetrahydroxybenzophenone	"2,2',4,4'-tetrahydroxybenzophenone results in increased expression of ESR2 mRNA"	15458797
C035476	2,2',4,4'-tetrahydroxybenzophenone	"2,2',4,4'-tetrahydroxybenzophenone binds to ESR2 protein"	19913605
C001508	2,2,4-trimethyl-1,3-pentanediol diisobutyrate	"2,2,4-trimethyl-1,3-pentanediol diisobutyrate binds to and results in increased activity of ESR2 protein"	27633901
C497827	2,2-bis(3-chloro-4-hydroxyphenyl)propane	"2,2-bis(3-chloro-4-hydroxyphenyl)propane binds to ESR2 protein"	15596252
C404910	2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane	"2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane binds to and results in decreased activity of ESR2 protein"	10579340\|1099995
C404910	2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane	"2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane binds to and results in increased activity of ESR2 protein"	15840436
C404910	2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane	"2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane inhibits the reaction [Genistein binds to and results in increased activity of ESR2 protein]"	11861976
C404910	2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane	"2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane results in decreased activity of ESR2 protein"	24994688
C404910	2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane	"2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane results in decreased expression of ESR2 mRNA"	11509743
C404910	2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane	"2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane results in increased expression of ESR2 mRNA"	11509743\|2125239
C404910	2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane	"ESR2 protein alternative form inhibits the reaction [2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane results in increased expression of ESR2 protein]"	27634370
C404910	2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane	"[Estradiol co-treated with 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane] results in decreased expression of ESR2 mRNA"	11509743
C404910	2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane	"[Estradiol co-treated with 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane] results in increased expression of ESR2 mRNA"	11509743
C404910	2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane	"NCOA1 protein promotes the reaction [2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane results in increased expression of ESR2 protein]"	27634370
C404910	2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane	"NCOA2 protein promotes the reaction [2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane results in increased expression of ESR2 protein]"	27634370
C404910	2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane	"NCOA3 protein promotes the reaction [2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane results in increased expression of ESR2 protein alternative form]"	27634370
C404910	2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane	"2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane binds to and results in decreased activity of ESR2 protein"	10579340
C404910	2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane	"2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane inhibits the reaction [FSHB protein results in increased expression of ESR2 mRNA]"	25549949
C404910	2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane	"2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane inhibits the reaction [FSHB protein results in increased expression of ESR2 protein]"	25549949
C404910	2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane	"2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane binds to and results in decreased activity of ESR2 protein"	11509743
C000600590	2,2-bis(4-hydroxyphenyl)hexafluoropropane	"2,2-bis(4-hydroxyphenyl)hexafluoropropane results in increased expression of ESR2 mRNA"	29093337
C000600590	2,2-bis(4-hydroxyphenyl)hexafluoropropane	"2,2-bis(4-hydroxyphenyl)hexafluoropropane results in increased expression of ESR2 protein"	29093337
C003585	22-hydroxycholesterol	22-hydroxycholesterol binds to and results in decreased activity of ESR2 protein	17873880
C003585	22-hydroxycholesterol	22-hydroxycholesterol inhibits the reaction [Estradiol results in increased activity of ESR2 protein]	17873880
C104006	2',3',4',5'-tetrachloro-4-biphenylol	"2',3',4',5'-tetrachloro-4-biphenylol binds to ESR2 protein"	10964929
C104006	2',3',4',5'-tetrachloro-4-biphenylol	"2',3',4',5'-tetrachloro-4-biphenylol inhibits the reaction [Estradiol binds to ESR2 protein]"	10964929
C104006	2',3',4',5'-tetrachloro-4-biphenylol	"2',3',4',5'-tetrachloro-4-biphenylol promotes the reaction [ESR2 protein binds to NCOA1 protein]"	10964929
C104006	2',3',4',5'-tetrachloro-4-biphenylol	"2',3',4',5'-tetrachloro-4-biphenylol promotes the reaction [ESR2 protein binds to NCOA2 protein]"	10964929
C101851	2-(((3,5-dichlorophenyl)carbamoyl)oxy)-2-methyl-3-butenoic acid	"2-(((3,5-dichlorophenyl)carbamoyl)oxy)-2-methyl-3-butenoic acid binds to and results in increased activity of ESR2 protein"	16750840
C486182	2,3-bis(4-hydroxyphenyl)-propionitrile	"2,3-bis(4-hydroxyphenyl)-propionitrile results in increased activity of ESR2 protein"	25106122
C486182	2,3-bis(4-hydroxyphenyl)-propionitrile	"2,3-bis(4-hydroxyphenyl)-propionitrile results in increased phosphorylation of and results in increased localization of and results in increased activity of ESR2 protein"	20623183
C486182	2,3-bis(4-hydroxyphenyl)-propionitrile	"ESR2 protein affects the reaction [2,3-bis(4-hydroxyphenyl)-propionitrile results in increased expression of BCL2 mRNA]"	19264808
C486182	2,3-bis(4-hydroxyphenyl)-propionitrile	"ESR2 protein affects the reaction [2,3-bis(4-hydroxyphenyl)-propionitrile results in increased expression of PDCD4 mRNA]"	19264808
C486182	2,3-bis(4-hydroxyphenyl)-propionitrile	"2,3-bis(4-hydroxyphenyl)-propionitrile binds to and results in increased activity of ESR2 protein"	18499763
C486182	2,3-bis(4-hydroxyphenyl)-propionitrile	"[2,3-bis(4-hydroxyphenyl)-propionitrile binds to and results in increased activity of ESR2 protein] which results in increased secretion of Bicarbonates"	18499763
C486182	2,3-bis(4-hydroxyphenyl)-propionitrile	"2,3-bis(4-hydroxyphenyl)-propionitrile results in increased expression of ESR2 protein"	27634370
C486182	2,3-bis(4-hydroxyphenyl)-propionitrile	"2,3-bis(4-hydroxyphenyl)-propionitrile results in increased expression of ESR2 protein alternative form"	27634370
C486182	2,3-bis(4-hydroxyphenyl)-propionitrile	"ESR2 protein alternative form inhibits the reaction [2,3-bis(4-hydroxyphenyl)-propionitrile results in increased expression of ESR2 protein]"	27634370
C486182	2,3-bis(4-hydroxyphenyl)-propionitrile	"2,3-bis(4-hydroxyphenyl)-propionitrile binds to and results in increased activity of ESR2 protein"	22257560
C486182	2,3-bis(4-hydroxyphenyl)-propionitrile	"[2,3-bis(4-hydroxyphenyl)-propionitrile binds to and results in increased activity of ESR2 protein] inhibits the reaction [resveratrol results in decreased expression of PRL protein]"	22104698
C486182	2,3-bis(4-hydroxyphenyl)-propionitrile	"2,3-bis(4-hydroxyphenyl)-propionitrile binds to and results in increased activity of ESR2 protein"	15994857\|1708840
C497826	2-(3-chloro-4-hydroxyphenyl)-2-(4-hydroxyphenyl)propane	2-(3-chloro-4-hydroxyphenyl)-2-(4-hydroxyphenyl)propane binds to ESR2 protein	15596252
C081766	2,4,4'-trichlorobiphenyl	"2,4,4'-trichlorobiphenyl analog binds to and results in increased activity of ESR2 protein"	21843587
C014024	2,4,5,2',4',5'-hexachlorobiphenyl	"2,4,5,2',4',5'-hexachlorobiphenyl results in increased expression of ESR2 mRNA"	27832956
C014024	2,4,5,2',4',5'-hexachlorobiphenyl	"2,4,5,2',4',5'-hexachlorobiphenyl results in decreased expression of ESR2 mRNA"	23146750
C015550	2,4',5-trichlorobiphenyl	"2,4',5-trichlorobiphenyl analog binds to and results in increased activity of ESR2 protein"	21843587
C067259	2,4,6-trichlorophenyl-4'-aminophenyl ether	"2,4,6-trichlorophenyl-4'-aminophenyl ether results in increased activity of ESR2 protein"	15064155
C526470	2,4,6-trimethylbenzaldehyde	"2,4,6-trimethylbenzaldehyde binds to and results in decreased activity of ESR2 protein"	27633901
C004762	2,4-dichlorophenol	"2,4-dichlorophenol binds to ESR2 protein"	12224631
C121479	2,4-dihydroxybenzophenone	"2,4-dihydroxybenzophenone analog results in increased expression of ESR2 mRNA"	18973785
C121479	2,4-dihydroxybenzophenone	"2,4-dihydroxybenzophenone binds to and results in increased activity of ESR2 protein"	16079615
C121479	2,4-dihydroxybenzophenone	"2,4-dihydroxybenzophenone binds to ESR2 protein"	19913605
C044563	24-hydroxycholesterol	24-hydroxycholesterol binds to and results in decreased activity of ESR2 protein	17873880
C044563	24-hydroxycholesterol	24-hydroxycholesterol inhibits the reaction [Estradiol results in increased activity of ESR2 protein]	17873880
C009407	2,5,2',5'-tetrachlorobiphenyl	"2,5,2',5'-tetrachlorobiphenyl results in increased expression of ESR2 mRNA"	26372180
C007997	25-hydroxycholesterol	25-hydroxycholesterol binds to and results in decreased activity of ESR2 protein	17873880
C007997	25-hydroxycholesterol	25-hydroxycholesterol inhibits the reaction [Estradiol results in increased activity of ESR2 protein]	17873880
C018520	2,6-diisopropylnaphthalene	"2,6-diisopropylnaphthalene binds to and results in increased activity of ESR2 protein"	27633901
C028519	2,6-dimethylnaphthalene	"2,6-dimethylnaphthalene binds to and results in increased activity of ESR2 protein"	27633901
C076996	27-hydroxycholesterol	27-hydroxycholesterol binds to and affects the folding of and results in increased activity of ESR2 protein	17872378
C076996	27-hydroxycholesterol	27-hydroxycholesterol binds to and results in decreased activity of ESR2 protein	17873880
C076996	27-hydroxycholesterol	27-hydroxycholesterol inhibits the reaction [Estradiol results in increased activity of ESR2 protein]	17873880
C076996	27-hydroxycholesterol	ESR2 protein affects the reaction [27-hydroxycholesterol results in decreased expression of NOS2 mRNA]	17873880
C076996	27-hydroxycholesterol	ESR2 protein affects the reaction [27-hydroxycholesterol results in decreased expression of NOS3 mRNA]	17873880
C076996	27-hydroxycholesterol	ESR2 protein affects the susceptibility to 27-hydroxycholesterol	17873880
C049584	2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine	"2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of ESR2 mRNA"	15637090
C049584	2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine	"2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of ESR2 protein"	15637090
C012257	2-chloro-4-phenylphenol	2-chloro-4-phenylphenol binds to and results in increased activity of ESR2 protein	21843587
C576261	2-ethylhexyl 2,3,4,5-tetrabromobenzoate	"[bis(2-ethylhexyl) 2,3,4,5-tetrabromophthalate co-treated with 2-ethylhexyl 2,3,4,5-tetrabromobenzoate] results in decreased expression of ESR2 mRNA"	25461741
C001390	2-hydroxyestradiol	2-hydroxyestradiol results in decreased expression of ESR2 protein	23685341
C001390	2-hydroxyestradiol	2-hydroxyestradiol inhibits the reaction [16 alpha-iodoestradiol binds to ESR2 protein]	9048584
C024980	2-hydroxyestrone	2-hydroxyestrone binds to and results in increased activity of ESR2 protein	17713618
C004369	2-phenylphenol	2-phenylphenol results in increased expression of ESR2 mRNA	12737316
C035406	2-tert-butylphenol	2-tert-butylphenol binds to ESR2 protein	19913605
C041525	3,3',4,5'-tetrahydroxystilbene	"3,3',4,5'-tetrahydroxystilbene results in increased activity of ESR2 protein"	17935960
C041525	3,3',4,5'-tetrahydroxystilbene	"fulvestrant inhibits the reaction [3,3',4,5'-tetrahydroxystilbene results in increased activity of ESR2 protein]"	17935960
C016392	3,3'-diindolylmethane	"3,3'-diindolylmethane promotes the reaction [ESR2 protein binds to KRT19 promoter]"	20160136
C016392	3,3'-diindolylmethane	"3,3'-diindolylmethane promotes the reaction [ESR2 protein binds to TMEM121B promoter]"	20160136
C016392	3,3'-diindolylmethane	"3,3'-diindolylmethane results in increased expression of ESR2 mRNA"	20160136
C016392	3,3'-diindolylmethane	"ESR2 affects the reaction [3,3'-diindolylmethane promotes the reaction [NCOA2 protein binds to KRT19 promoter]]"	20160136
C016392	3,3'-diindolylmethane	"ESR2 affects the reaction [3,3'-diindolylmethane results in increased expression of KRT19 mRNA]"	20160136
C016392	3,3'-diindolylmethane	"ESR2 affects the reaction [3,3'-diindolylmethane results in increased expression of TMEM121B mRNA]"	20160136
C016392	3,3'-diindolylmethane	"Raloxifene Hydrochloride inhibits the reaction [3,3'-diindolylmethane results in increased expression of ESR2 mRNA]"	20160136
C016392	3,3'-diindolylmethane	"Tamoxifen inhibits the reaction [3,3'-diindolylmethane results in increased expression of ESR2 mRNA]"	20160136
C016392	3,3'-diindolylmethane	"3,3'-diindolylmethane results in increased expression of ESR2 mRNA"	27092574
C013279	3,4,3',4'-tetrachloroazobenzene	"3,4,3',4'-tetrachloroazobenzene binds to ESR2 protein"	26878642
C028451	3,4,3',4'-tetrachlorobiphenyl	"3,4,3',4'-tetrachlorobiphenyl inhibits the reaction [nonylphenol results in increased expression of ESR2 mRNA]"	16291559
C028451	3,4,3',4'-tetrachlorobiphenyl	"3,4,3',4'-tetrachlorobiphenyl results in decreased expression of ESR2 mRNA"	17291011
C028451	3,4,3',4'-tetrachlorobiphenyl	"[4-nonylphenol co-treated with 3,4,3',4'-tetrachlorobiphenyl] results in decreased expression of ESR2 mRNA"	17291011
C028451	3,4,3',4'-tetrachlorobiphenyl	"alpha-naphthoflavone inhibits the reaction [3,4,3',4'-tetrachlorobiphenyl results in decreased expression of ESR2 mRNA]"	17291011
C028451	3,4,3',4'-tetrachlorobiphenyl	"fulvestrant inhibits the reaction [[4-nonylphenol co-treated with 3,4,3',4'-tetrachlorobiphenyl] results in decreased expression of ESR2 mRNA]"	17291011
C028451	3,4,3',4'-tetrachlorobiphenyl	"Tamoxifen inhibits the reaction [[4-nonylphenol co-treated with 3,4,3',4'-tetrachlorobiphenyl] results in decreased expression of ESR2 mRNA]"	17291011
C023035	3,4,5,3',4'-pentachlorobiphenyl	"3,4,5,3',4'-pentachlorobiphenyl inhibits the reaction [LHB protein results in increased expression of ESR2 mRNA]"	27832956
C023035	3,4,5,3',4'-pentachlorobiphenyl	"3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ESR2 mRNA"	27832956
C053286	3,4-dihydroxybenzaldoxime	"3,4-dihydroxybenzaldoxime analog binds to and results in increased activity of ESR2 protein"	12954056
C101850	3',5'-dichloro-2-hydroxy-2-methylbut-3-enanilide	"3',5'-dichloro-2-hydroxy-2-methylbut-3-enanilide binds to and results in increased activity of ESR2 protein"	16750840
C029904	3,5-dichlorobiphenyl	"3,5-dichlorobiphenyl analog binds to and results in increased activity of ESR2 protein"	21843587
C026423	3,8-dihydroxy-6H-dibenzo(b,d)pyran-6-one	"3,8-dihydroxy-6H-dibenzo(b,d)pyran-6-one binds to and affects the activity of ESR2 protein"	16506809
C511303	3-benzylidene camphor	3-benzylidene camphor binds to ESR2 protein	15147785
C511303	3-benzylidene camphor	3-benzylidene camphor results in decreased expression of ESR2 mRNA	19150460
C047368	3-methylquercetin	3-methylquercetin binds to ESR2 protein	14706564
C496952	4-(2-chloro-4-(2-piperidin-1-ylethoxy)phenyl)-5-(2,6-dichloro-4-hydroxyphenyl)-2-imidazoline	"4-(2-chloro-4-(2-piperidin-1-ylethoxy)phenyl)-5-(2,6-dichloro-4-hydroxyphenyl)-2-imidazoline binds to and results in increased activity of ESR2 protein"	15658860
C556295	4-(2-phenyl-5,7-bis(trifluoromethyl)pyrazolo(1,5-a)pyrimidin-3-yl)phenol	"4-(2-phenyl-5,7-bis(trifluoromethyl)pyrazolo(1,5-a)pyrimidin-3-yl)phenol binds to and results in decreased activity of ESR2 protein"	24425189
C556295	4-(2-phenyl-5,7-bis(trifluoromethyl)pyrazolo(1,5-a)pyrimidin-3-yl)phenol	"4-(2-phenyl-5,7-bis(trifluoromethyl)pyrazolo(1,5-a)pyrimidin-3-yl)phenol results in decreased activity of ESR2 protein"	25106122\|2707194
C556295	4-(2-phenyl-5,7-bis(trifluoromethyl)pyrazolo(1,5-a)pyrimidin-3-yl)phenol	"[4-(2-phenyl-5,7-bis(trifluoromethyl)pyrazolo(1,5-a)pyrimidin-3-yl)phenol results in decreased activity of ESR2 protein] inhibits the reaction [Estradiol results in increased activity of ESR2 protein]"	22613215
C556295	4-(2-phenyl-5,7-bis(trifluoromethyl)pyrazolo(1,5-a)pyrimidin-3-yl)phenol	"[4-(2-phenyl-5,7-bis(trifluoromethyl)pyrazolo(1,5-a)pyrimidin-3-yl)phenol results in decreased activity of ESR2 protein] inhibits the reaction [icaritin results in increased activity of ESR2 protein]"	22613215
C556295	4-(2-phenyl-5,7-bis(trifluoromethyl)pyrazolo(1,5-a)pyrimidin-3-yl)phenol	"4-(2-phenyl-5,7-bis(trifluoromethyl)pyrazolo(1,5-a)pyrimidin-3-yl)phenol results in increased expression of ESR2 protein"	19270784
C556295	4-(2-phenyl-5,7-bis(trifluoromethyl)pyrazolo(1,5-a)pyrimidin-3-yl)phenol	"4-(2-phenyl-5,7-bis(trifluoromethyl)pyrazolo(1,5-a)pyrimidin-3-yl)phenol results in decreased activity of ESR2 protein"	21278053\|2261321
C486184	4,4',4''-(4-propyl-((1)H)-pyrazole-1,3,5-triyl) tris-phenol	"4,4',4''-(4-propyl-((1)H)-pyrazole-1,3,5-triyl) tris-phenol binds to and results in increased activity of ESR2 protein"	24425189
C486184	4,4',4''-(4-propyl-((1)H)-pyrazole-1,3,5-triyl) tris-phenol	"4,4',4''-(4-propyl-((1)H)-pyrazole-1,3,5-triyl) tris-phenol results in increased expression of ESR2 mRNA"	15207704
C486184	4,4',4''-(4-propyl-((1)H)-pyrazole-1,3,5-triyl) tris-phenol	"ESR2 protein affects the reaction [4,4',4''-(4-propyl-((1)H)-pyrazole-1,3,5-triyl) tris-phenol results in increased expression of BCL2 mRNA]"	19264808
C486184	4,4',4''-(4-propyl-((1)H)-pyrazole-1,3,5-triyl) tris-phenol	"ESR2 protein affects the reaction [4,4',4''-(4-propyl-((1)H)-pyrazole-1,3,5-triyl) tris-phenol results in increased expression of PDCD4 mRNA]"	19264808
C486184	4,4',4''-(4-propyl-((1)H)-pyrazole-1,3,5-triyl) tris-phenol	"4,4',4''-(4-propyl-((1)H)-pyrazole-1,3,5-triyl) tris-phenol affects the localization of ESR2 protein"	22070562
C486184	4,4',4''-(4-propyl-((1)H)-pyrazole-1,3,5-triyl) tris-phenol	"4,4',4''-(4-propyl-((1)H)-pyrazole-1,3,5-triyl) tris-phenol results in increased expression of ESR2 protein"	22070562
C008745	4,4'-bisphenol F	"4,4'-bisphenol F results in increased expression of ESR2 mRNA"	18973785
C009505	4,4'-diaminodiphenylmethane	"4,4'-diaminodiphenylmethane results in decreased expression of ESR2 mRNA"	18648102
C583074	4,4'-hexafluorisopropylidene diphenol	"4,4'-hexafluorisopropylidene diphenol results in increased expression of ESR2 protein"	27634370
C583074	4,4'-hexafluorisopropylidene diphenol	"4,4'-hexafluorisopropylidene diphenol results in increased expression of ESR2 protein alternative form"	27634370
C583074	4,4'-hexafluorisopropylidene diphenol	"ESR2 protein alternative form inhibits the reaction [4,4'-hexafluorisopropylidene diphenol results in increased expression of ESR2 protein]"	27634370
C583074	4,4'-hexafluorisopropylidene diphenol	"NCOA1 protein promotes the reaction [4,4'-hexafluorisopropylidene diphenol results in increased expression of ESR2 protein]"	27634370
C583074	4,4'-hexafluorisopropylidene diphenol	"NCOA2 protein promotes the reaction [4,4'-hexafluorisopropylidene diphenol results in increased expression of ESR2 protein]"	27634370
C583074	4,4'-hexafluorisopropylidene diphenol	"NCOA3 protein promotes the reaction [4,4'-hexafluorisopropylidene diphenol results in increased expression of ESR2 protein]"	27634370
C580935	4-((4-hydroxyphenylimino)methyl)benzene-1,2-diol	"4-((4-hydroxyphenylimino)methyl)benzene-1,2-diol results in increased expression of ESR2 mRNA"	25242450
C580935	4-((4-hydroxyphenylimino)methyl)benzene-1,2-diol	"4-((4-hydroxyphenylimino)methyl)benzene-1,2-diol results in increased expression of ESR2 protein"	25242450
C580935	4-((4-hydroxyphenylimino)methyl)benzene-1,2-diol	"ESR2 protein promotes the reaction [4-((4-hydroxyphenylimino)methyl)benzene-1,2-diol results in decreased expression of MYC protein]"	25242450
C580935	4-((4-hydroxyphenylimino)methyl)benzene-1,2-diol	"ESR2 protein results in increased susceptibility to 4-((4-hydroxyphenylimino)methyl)benzene-1,2-diol"	25242450
C042291	4-ethylphenol	4-ethylphenol binds to ESR2 protein	12224631\|1991360
C042291	4-ethylphenol	4-ethylphenol affects the localization of ESR2 protein	20950447
C477728	4-fluorobenzoyl-TN-14003	4-fluorobenzoyl-TN-14003 inhibits the reaction [CXCL12 protein results in increased activity of ESR2 protein]	19584281
C477728	4-fluorobenzoyl-TN-14003	4-fluorobenzoyl-TN-14003 inhibits the reaction [CXCL12 protein results in increased phosphorylation of ESR2 protein]	19584281
C024292	4-hydroxybenzophenone	4-hydroxybenzophenone binds to and results in increased activity of ESR2 protein	16079615
C014036	4-hydroxyestradiol	4-hydroxyestradiol binds to ESR2 protein	15993745
C014036	4-hydroxyestradiol	4-hydroxyestradiol results in decreased expression of ESR2 protein	23685341
C014036	4-hydroxyestradiol	4-hydroxyestradiol inhibits the reaction [16 alpha-iodoestradiol binds to ESR2 protein]	9048584
C504750	4-methyl-2,4-bis(4-hydroxyphenyl)pent-1-ene	"4-methyl-2,4-bis(4-hydroxyphenyl)pent-1-ene affects the reaction [Estradiol binds to ESR2 protein]"	23056236
C504750	4-methyl-2,4-bis(4-hydroxyphenyl)pent-1-ene	"4-methyl-2,4-bis(4-hydroxyphenyl)pent-1-ene binds to ESR2 protein"	14691209
C504750	4-methyl-2,4-bis(4-hydroxyphenyl)pent-1-ene	"4-methyl-2,4-bis(4-hydroxyphenyl)pent-1-ene results in increased expression of ESR2 protein"	24231368
C504750	4-methyl-2,4-bis(4-hydroxyphenyl)pent-1-ene	"4-methyl-2,4-bis(4-hydroxyphenyl)pent-1-ene affects the expression of ESR2 mRNA"	20435109
C020627	4-methylbenzaldehyde	4-methylbenzaldehyde binds to and results in decreased activity of ESR2 protein	27633901
C024836	4-nitrophenol	4-nitrophenol results in decreased expression of ESR2 mRNA	24070737
C017572	4-nitrotoluene	4-nitrotoluene binds to ESR2 protein	12224631
C041594	4-nonylphenol	4-nonylphenol binds to and results in increased activity of ESR2 protein	27633901
C041594	4-nonylphenol	4-nonylphenol binds to ESR2 protein	11518614\|1222463
C041594	4-nonylphenol	[4-nonylphenol co-treated with ESR2 protein] results in increased expression of LTF mRNA	21783566
C041594	4-nonylphenol	4-nonylphenol binds to ESR2 protein	15081833\|1991360
C041594	4-nonylphenol	4-nonylphenol results in decreased expression of ESR2 mRNA	16759644
C041594	4-nonylphenol	4-nonylphenol affects the localization of ESR2 protein	20950447
C041594	4-nonylphenol	4-nonylphenol analog results in decreased expression of ESR2 mRNA	27086933
C041594	4-nonylphenol	4-nonylphenol analog results in decreased expression of ESR2 protein	27086933
C041594	4-nonylphenol	4-nonylphenol inhibits the reaction [Estradiol results in increased expression of ESR2 mRNA]	22056370
C041594	4-nonylphenol	4-nonylphenol results in increased expression of ESR2 mRNA	17258427
C041594	4-nonylphenol	4-nonylphenol binds to ESR2 protein	19913605
C041594	4-nonylphenol	"[4-nonylphenol co-treated with 3,4,3',4'-tetrachlorobiphenyl] results in decreased expression of ESR2 mRNA"	17291011
C041594	4-nonylphenol	"fulvestrant inhibits the reaction [[4-nonylphenol co-treated with 3,4,3',4'-tetrachlorobiphenyl] results in decreased expression of ESR2 mRNA]"	17291011
C041594	4-nonylphenol	"Tamoxifen inhibits the reaction [[4-nonylphenol co-treated with 3,4,3',4'-tetrachlorobiphenyl] results in decreased expression of ESR2 mRNA]"	17291011
C041594	4-nonylphenol	4-nonylphenol results in increased activity of ESR2 protein	11403899
C080417	4-octylphenol	4-octylphenol binds to ESR2 protein	19913605
C080417	4-octylphenol	[4-octylphenol co-treated with ESR2 protein] results in increased expression of LTF mRNA	21783566
C080417	4-octylphenol	4-octylphenol binds to ESR2 protein	15081833
C080417	4-octylphenol	4-octylphenol affects the localization of ESR2 protein	20950447
C019046	4-phenylphenol	4-phenylphenol results in increased expression of ESR2 mRNA	12737316
C099327	4-propylphenol	4-propylphenol affects the localization of ESR2 protein	20950447
C105260	4-tert-octylphenol	4-tert-octylphenol binds to and results in increased activity of ESR2 protein	27633901
C105260	4-tert-octylphenol	4-tert-octylphenol binds to ESR2 protein	10964929\|1216100
C105260	4-tert-octylphenol	4-tert-octylphenol inhibits the reaction [Estradiol binds to ESR2 protein]	10964929
C105260	4-tert-octylphenol	4-tert-octylphenol promotes the reaction [ESR2 protein binds to NCOA1 protein]	10964929
C105260	4-tert-octylphenol	4-tert-octylphenol promotes the reaction [ESR2 protein binds to NCOA2 protein]	10964929
C105260	4-tert-octylphenol	4-tert-octylphenol results in increased expression of ESR2 mRNA	12737316
C105260	4-tert-octylphenol	4-tert-octylphenol binds to ESR2 protein	19913605
C105260	4-tert-octylphenol	4-tert-octylphenol results in increased expression of ESR2 mRNA	17258427
C105260	4-tert-octylphenol	4-tert-octylphenol binds to ESR2 protein	19913605
C120076	5,11-diethyl-5,6,11,12-tetrahydrochrysene-2,8-diol	"5,11-diethyl-5,6,11,12-tetrahydrochrysene-2,8-diol inhibits the reaction [[Estradiol co-treated with ESR2] results in increased expression of NOS2 mRNA]"	11583108
C120076	5,11-diethyl-5,6,11,12-tetrahydrochrysene-2,8-diol	"5,11-diethyl-5,6,11,12-tetrahydrochrysene-2,8-diol inhibits the reaction [[Estradiol co-treated with ESR2] results in increased expression of NOS3 mRNA]"	11583108
C120076	5,11-diethyl-5,6,11,12-tetrahydrochrysene-2,8-diol	"5,11-diethyl-5,6,11,12-tetrahydrochrysene-2,8-diol binds to and results in decreased activity of ESR2 protein"	15465114
C120076	5,11-diethyl-5,6,11,12-tetrahydrochrysene-2,8-diol	"5,11-diethyl-5,6,11,12-tetrahydrochrysene-2,8-diol inhibits the reaction [Estradiol results in increased activity of ESR2 protein]"	11583108
C113977	5-octylphenol	5-octylphenol binds to ESR2 protein	11518614
C580598	5-OH-BDE-47	5-OH-BDE-47 results in decreased expression of ESR2 protein	26988655
C580598	5-OH-BDE-47	fulvestrant promotes the reaction [5-OH-BDE-47 results in decreased expression of ESR2 protein]	26988655
C580599	6-OH-BDE-47	6-OH-BDE-47 affects the expression of ESR2 protein	26988655
C580599	6-OH-BDE-47	6-OH-BDE-47 promotes the reaction [fulvestrant results in decreased expression of ESR2 protein]	26988655
C580599	6-OH-BDE-47	fulvestrant promotes the reaction [6-OH-BDE-47 affects the expression of ESR2 protein]	26988655
C121707	7,3'-dihydroxy-4'-methoxyisoflavone	"7,3'-dihydroxy-4'-methoxyisoflavone binds to ESR2 protein"	20686605
C121707	7,3'-dihydroxy-4'-methoxyisoflavone	"7,3'-dihydroxy-4'-methoxyisoflavone inhibits the reaction [Estradiol binds to ESR2 protein]"	20686605
C475050	7alpha-methyl-17alpha-ethynylestradiol	7alpha-methyl-17alpha-ethynylestradiol binds to ESR2 protein	12117614
C529431	8-2 fluorotelomer alcohol	8-2 fluorotelomer alcohol results in increased expression of ESR2 mRNA	21984479
C119737	8-prenylnaringenin	8-prenylnaringenin analog binds to and results in decreased activity of ESR2 protein	17149865
C119737	8-prenylnaringenin	8-prenylnaringenin binds to and results in increased activity of ESR2 protein	16076101
C119737	8-prenylnaringenin	8-prenylnaringenin results in increased activity of ESR2 protein	17716812
C119737	8-prenylnaringenin	8-prenylnaringenin results in decreased expression of ESR2 mRNA	16522720
C559335	9,9-bis(4-hydroxyphenyl)fluorene	"9,9-bis(4-hydroxyphenyl)fluorene inhibits the reaction [Estradiol results in increased activity of ESR2 protein]"	28248286
C091375	9-phenanthrol	9-phenanthrol inhibits the reaction [ESR2 protein binds to Estradiol]	22989670
C091375	9-phenanthrol	ESR2 protein binds to 9-phenanthrol	22989670
C091375	9-phenanthrol	9-phenanthrol promotes the reaction [ESR2 protein binds to ESR2 protein]	22989670
C091375	9-phenanthrol	9-phenanthrol results in increased activity of ESR2 protein	22989670
C091375	9-phenanthrol	fulvestrant inhibits the reaction [9-phenanthrol results in increased activity of ESR2 protein]	22989670
C038699	acetophenone	acetophenone binds to and results in decreased activity of ESR2 protein	27633901
D000111	Acetylcysteine	Acetylcysteine inhibits the reaction [SOD2 protein affects the expression of ESR2 mRNA]	18829485
C033116	acetyl methyl tetramethyl tetralin	acetyl methyl tetramethyl tetralin binds to and results in decreased activity of ESR2 protein	15537743
D000242	Cyclic AMP	ESR2 protein promotes the reaction [[CGB3 protein results in increased activity of LHCGR protein] which results in increased abundance of Cyclic AMP]	19766106
D000242	Cyclic AMP	Colforsin inhibits the reaction [ESR2 gene mutant form inhibits the reaction [CGA protein results in increased abundance of Cyclic AMP]]	20378682
D000242	Cyclic AMP	ESR2 gene mutant form inhibits the reaction [CGA protein results in increased abundance of Cyclic AMP]	20378682
D000242	Cyclic AMP	[ESR2 gene mutant form results in decreased expression of LHCGR protein] inhibits the reaction [CGA protein results in increased abundance of Cyclic AMP]	20378682
C016601	afimoxifene	afimoxifene affects the expression of ESR2 protein	15721411
C016601	afimoxifene	afimoxifene binds to and results in decreased activity of ESR2 protein	15537743
C016601	afimoxifene	afimoxifene binds to ESR2 protein	17203231\|1991360
C016601	afimoxifene	afimoxifene inhibits the reaction [Estradiol binds to ESR2 protein]	9751507
C016601	afimoxifene	afimoxifene inhibits the reaction [Estradiol results in increased activity of ESR2 protein]	28248286
C016601	afimoxifene	afimoxifene inhibits the reaction [methoxyacetic acid promotes the reaction [Estradiol results in increased activity of ESR2 protein]]	15103026
C016601	afimoxifene	ESR2 protein results in increased susceptibility to afimoxifene	15821116
C016601	afimoxifene	afimoxifene binds to ESR2 protein	19913605
C016601	afimoxifene	afimoxifene inhibits the reaction [16 alpha-iodoestradiol binds to ESR2 protein]	9048584
C016601	afimoxifene	afimoxifene inhibits the reaction [Estradiol binds to ESR2 protein alternative form]	9492041
D000452	Aldrin	Aldrin binds to and results in decreased activity of ESR2 protein	16626760
C103303	alitretinoin	alitretinoin inhibits the reaction [Paclitaxel results in increased expression of ESR2 mRNA]	19340624
C100185	(all-E) phytoene	[(all-E) phytoene co-treated with phytofluene] inhibits the reaction [Estradiol results in increased activity of ESR2 protein]	17051425
D013196	Dihydrotestosterone	AR protein mutant form affects the reaction [Dihydrotestosterone results in decreased expression of ESR2 protein]	18007998
D013196	Dihydrotestosterone	Dihydrotestosterone results in decreased expression of ESR2 mRNA	18007998
D013196	Dihydrotestosterone	Dihydrotestosterone results in decreased expression of ESR2 protein	18007998
D013196	Dihydrotestosterone	Dihydrotestosterone results in increased activity of ESR2 protein	15171712
D013196	Dihydrotestosterone	Dihydrotestosterone results in increased localization of ESR2 protein	15171712
D013196	Dihydrotestosterone	fulvestrant inhibits the reaction [Dihydrotestosterone results in increased activity of ESR2 protein]	15171712
D013196	Dihydrotestosterone	fulvestrant inhibits the reaction [Dihydrotestosterone results in increased localization of ESR2 protein]	15171712
C040534	alpha-hexachlorocyclohexane	alpha-hexachlorocyclohexane results in increased activity of ESR2 protein	15064155
C011512	alpha-naphthoflavone	[alpha-naphthoflavone co-treated with beta-Naphthoflavone] results in decreased expression of ESR2 mRNA	22975028
C011512	alpha-naphthoflavone	"alpha-naphthoflavone inhibits the reaction [3,4,3',4'-tetrachlorobiphenyl results in decreased expression of ESR2 mRNA]"	17291011
D024502	alpha-Tocopherol	[alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of ESR2 mRNA]	22389237
C010845	aluminum chloride	[Genistein co-treated with aluminum chloride] results in increased expression of ESR2 mRNA	28552514
C010845	aluminum chloride	[Plant Extracts co-treated with aluminum chloride] results in increased expression of ESR2 mRNA	28552514
D000643	Ammonium Chloride	Ammonium Chloride affects the expression of ESR2 mRNA	16483693
C553921	amurensin G	[Chrysenes binds to and results in decreased activity of ESR2 protein] inhibits the reaction [amurensin G results in increased phosphorylation of NOS3 protein]	22982565
C553921	amurensin G	ESR2 protein affects the reaction [amurensin G results in increased phosphorylation of NOS3 protein]	22982565
D015113	Androstane-3,17-diol	"Androstane-3,17-diol analog binds to and results in increased activity of ESR2 protein"	17003281
D015113	Androstane-3,17-diol	"Androstane-3,17-diol binds to and results in increased activity of ESR2 protein"	17003281
D015113	Androstane-3,17-diol	"fulvestrant inhibits the reaction [Androstane-3,17-diol analog binds to and results in increased activity of ESR2 protein]"	17003281
D015113	Androstane-3,17-diol	"fulvestrant inhibits the reaction [Androstane-3,17-diol binds to and results in increased activity of ESR2 protein]"	17003281
D015113	Androstane-3,17-diol	"Androstane-3,17-diol binds to ESR2 protein"	16452668
D015113	Androstane-3,17-diol	"Androstane-3,17-diol inhibits the reaction [Estradiol binds to ESR2 protein]"	8650195
D015113	Androstane-3,17-diol	"Androstane-3,17-diol results in increased activity of ESR2 protein"	8650195
D015114	Androstenediol	Androstenediol results in increased expression of ESR2 protein	27634370
D015114	Androstenediol	ESR2 protein alternative form inhibits the reaction [Androstenediol results in increased expression of ESR2 protein]	27634370
D015114	Androstenediol	Androstenediol inhibits the reaction [16 alpha-iodoestradiol binds to ESR2 protein]	9048584
D000814	Aniline Compounds	Aniline Compounds binds to and results in increased activity of ESR2 protein	25123791
D000814	Aniline Compounds	Aniline Compounds results in increased expression of ESR2 protein	25123791
C102351	apicidin	apicidin results in decreased expression of ESR2 protein	18313654
D047310	Apigenin	Apigenin binds to and results in increased activity of ESR2 protein	9751507
D047310	Apigenin	Apigenin binds to ESR2 protein	12224631
D047310	Apigenin	Apigenin inhibits the reaction [Estradiol binds to ESR2 protein]	9751507
D047310	Apigenin	Apigenin results in increased activity of ESR2 protein	16118406\|1686097
D001149	Arsenates	[Arsenates co-treated with Atrazine] results in increased expression of ESR2 mRNA	18585445
D001149	Arsenates	Arsenates results in increased expression of ESR2 mRNA	18585445
D001151	Arsenic	Arsenic results in increased expression of ESR2 mRNA	24964631
D001151	Arsenic	[Arsenic co-treated with Estradiol co-treated with Triiodothyronine] results in decreased expression of ESR2 mRNA	27338438
D001151	Arsenic	Arsenic results in decreased expression of ESR2 mRNA	27338438
D001151	Arsenic	[bisphenol A co-treated with Zearalenone co-treated with Arsenic co-treated with enzacamene co-treated with Estradiol co-treated with Triiodothyronine] results in decreased expression of ESR2 mRNA	27338438
D001151	Arsenic	[bisphenol A co-treated with Zearalenone co-treated with Arsenic co-treated with enzacamene] results in increased expression of ESR2 mRNA	27338438
C006632	arsenic trioxide	[arsenic trioxide co-treated with Bortezomib] results in decreased expression of ESR2 mRNA	25913414
C015001	arsenite	arsenite results in increased methylation of ESR2 promoter	23974009
D001205	Ascorbic Acid	Ascorbic Acid inhibits the reaction [chromium hexavalent ion results in decreased expression of ESR2 mRNA]	18602937
D001280	Atrazine	[Arsenates co-treated with Atrazine] results in increased expression of ESR2 mRNA	18585445
D001280	Atrazine	Atrazine results in increased expression of ESR2 mRNA	18585445
D001280	Atrazine	Atrazine results in decreased expression of ESR2 mRNA	22285353
C447119	bazedoxifene	bazedoxifene binds to ESR2 protein	15961563
D019324	beta-Naphthoflavone	[alpha-naphthoflavone co-treated with beta-Naphthoflavone] results in decreased expression of ESR2 mRNA	22975028
C020225	benzohydrol	benzohydrol binds to and results in increased activity of ESR2 protein	16079615
C047723	benzophenone	benzophenone binds to and results in increased activity of ESR2 protein	16079615\|2763390
C047723	benzophenone	benzophenone binds to ESR2 protein	12224631
D001564	Benzo(a)pyrene	Benzo(a)pyrene affects the reaction [Estradiol affects the expression of ESR2 mRNA]	22425873
D001564	Benzo(a)pyrene	Benzo(a)pyrene results in decreased expression of ESR2 mRNA	21569818
D001564	Benzo(a)pyrene	Benzo(a)pyrene results in decreased expression of ESR2 mRNA	28651000
C006723	benzyl benzoate	benzyl benzoate inhibits the reaction [Estradiol binds to ESR2 protein]	19338011
C072553	benzyloxycarbonylleucyl-leucyl-leucine aldehyde	benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Estradiol results in increased expression of ESR2 mRNA]	15207704
C072553	benzyloxycarbonylleucyl-leucyl-leucine aldehyde	benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of ESR2 protein	14702340
C057775	benzylparaben	benzylparaben binds to and results in increased activity of ESR2 protein	23567241
C039672	benzyl salicylate	benzyl salicylate inhibits the reaction [Estradiol binds to ESR2 protein]	19338011
D019207	beta Carotene	beta Carotene inhibits the reaction [Estradiol results in increased activity of ESR2 protein]	17051425
D019207	beta Carotene	beta Carotene inhibits the reaction [Genistein results in increased activity of ESR2 protein]	17051425
D004958	Estradiol	Estradiol inhibits the reaction [ESR2 protein binds to CAV1 protein]	18296501
D004958	Estradiol	Benzo(a)pyrene affects the reaction [Estradiol affects the expression of ESR2 mRNA]	22425873
D004958	Estradiol	Estradiol affects the expression of ESR2 mRNA	22425873
D004958	Estradiol	Estradiol results in increased expression of ESR2 mRNA	27153368
D004958	Estradiol	Estradiol results in increased activity of ESR2 protein	12387416
D004958	Estradiol	daidzein inhibits the reaction [Estradiol results in increased expression of ESR2 mRNA]	20043933
D004958	Estradiol	Estradiol binds to ESR2 protein	24375616
D004958	Estradiol	Estradiol results in increased expression of ESR2 mRNA	20043933
D004958	Estradiol	Estradiol results in increased expression of ESR2 mRNA	26372180
D004958	Estradiol	1-hydroxypyrene inhibits the reaction [ESR2 protein binds to Estradiol]	22989670
D004958	Estradiol	1-naphthol inhibits the reaction [ESR2 protein binds to Estradiol]	22989670
D004958	Estradiol	"2,2',4,4',5-brominated diphenyl ether inhibits the reaction [Estradiol results in increased activity of ESR2 protein]"	19672399
D004958	Estradiol	22-hydroxycholesterol inhibits the reaction [Estradiol results in increased activity of ESR2 protein]	17873880
D004958	Estradiol	"2',3',4',5'-tetrachloro-4-biphenylol inhibits the reaction [Estradiol binds to ESR2 protein]"	10964929
D004958	Estradiol	24-hydroxycholesterol inhibits the reaction [Estradiol results in increased activity of ESR2 protein]	17873880
D004958	Estradiol	25-hydroxycholesterol inhibits the reaction [Estradiol results in increased activity of ESR2 protein]	17873880
D004958	Estradiol	27-hydroxycholesterol inhibits the reaction [Estradiol results in increased activity of ESR2 protein]	17873880
D004958	Estradiol	"[4-(2-phenyl-5,7-bis(trifluoromethyl)pyrazolo(1,5-a)pyrimidin-3-yl)phenol results in decreased activity of ESR2 protein] inhibits the reaction [Estradiol results in increased activity of ESR2 protein]"	22613215
D004958	Estradiol	"4-methyl-2,4-bis(4-hydroxyphenyl)pent-1-ene affects the reaction [Estradiol binds to ESR2 protein]"	23056236
D004958	Estradiol	4-tert-octylphenol inhibits the reaction [Estradiol binds to ESR2 protein]	10964929
D004958	Estradiol	"5,11-diethyl-5,6,11,12-tetrahydrochrysene-2,8-diol inhibits the reaction [[Estradiol co-treated with ESR2] results in increased expression of NOS2 mRNA]"	11583108
D004958	Estradiol	"5,11-diethyl-5,6,11,12-tetrahydrochrysene-2,8-diol inhibits the reaction [[Estradiol co-treated with ESR2] results in increased expression of NOS3 mRNA]"	11583108
D004958	Estradiol	"9,9-bis(4-hydroxyphenyl)fluorene inhibits the reaction [Estradiol results in increased activity of ESR2 protein]"	28248286
D004958	Estradiol	9-phenanthrol inhibits the reaction [ESR2 protein binds to Estradiol]	22989670
D004958	Estradiol	afimoxifene inhibits the reaction [Estradiol binds to ESR2 protein]	9751507
D004958	Estradiol	afimoxifene inhibits the reaction [Estradiol results in increased activity of ESR2 protein]	28248286
D004958	Estradiol	afimoxifene inhibits the reaction [methoxyacetic acid promotes the reaction [Estradiol results in increased activity of ESR2 protein]]	15103026
D004958	Estradiol	AHR protein inhibits the reaction [Estradiol results in increased expression of ESR2 mRNA]	15207704
D004958	Estradiol	[(all-E) phytoene co-treated with phytofluene] inhibits the reaction [Estradiol results in increased activity of ESR2 protein]	17051425
D004958	Estradiol	Apigenin inhibits the reaction [Estradiol binds to ESR2 protein]	9751507
D004958	Estradiol	benzyl benzoate inhibits the reaction [Estradiol binds to ESR2 protein]	19338011
D004958	Estradiol	benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Estradiol results in increased expression of ESR2 mRNA]	15207704
D004958	Estradiol	benzyl salicylate inhibits the reaction [Estradiol binds to ESR2 protein]	19338011
D004958	Estradiol	beta Carotene inhibits the reaction [Estradiol results in increased activity of ESR2 protein]	17051425
D004958	Estradiol	biochanin A inhibits the reaction [Estradiol binds to ESR2 protein]	16566672
D004958	Estradiol	bisphenol A analog inhibits the reaction [Estradiol binds to and results in increased activity of ESR2 protein]	20427257
D004958	Estradiol	bisphenol A inhibits the reaction [Estradiol binds to ESR2 protein]	10964929\|1125896
D004958	Estradiol	bisphenol A inhibits the reaction [Estradiol results in increased expression of ESR2 protein]	20836126
D004958	Estradiol	Butylated Hydroxyanisole inhibits the reaction [Estradiol binds to ESR2 protein]	12822488
D004958	Estradiol	butylbenzyl phthalate inhibits the reaction [Estradiol results in increased activity of ESR2 protein]	28571686
D004958	Estradiol	Butyric Acid promotes the reaction [Estradiol results in increased activity of ESR2 protein]	15103026
D004958	Estradiol	Chlordecone inhibits the reaction [Estradiol binds to ESR2 protein]	9751507
D004958	Estradiol	citral inhibits the reaction [Estradiol binds to ESR2 protein]	12495555
D004958	Estradiol	Coumestrol inhibits the reaction [Estradiol binds to ESR2 protein]	16566672\|9751507
D004958	Estradiol	Cycloheximide promotes the reaction [Estradiol results in increased expression of ESR2 mRNA]	15207704
D004958	Estradiol	daidzein inhibits the reaction [Estradiol binds to ESR2 protein]	16566672
D004958	Estradiol	daidzein promotes the reaction [Estradiol results in increased activity of ESR2 protein]	16118406
D004958	Estradiol	Dibutyl Phthalate inhibits the reaction [Estradiol results in increased activity of ESR2 protein]	28571686
D004958	Estradiol	dicyclohexyl phthalate inhibits the reaction [Estradiol results in increased activity of ESR2 protein]	28571686\|2871710
D004958	Estradiol	Dieldrin promotes the reaction [Estradiol results in increased expression of ESR2 mRNA]	15261991
D004958	Estradiol	Diethylhexyl Phthalate inhibits the reaction [Estradiol results in increased activity of ESR2 protein]	28571686
D004958	Estradiol	Diethylstilbestrol inhibits the reaction [Estradiol binds to ESR2 protein]	10964929\|9751507
D004958	Estradiol	diisobutyl phthalate inhibits the reaction [Estradiol results in increased activity of ESR2 protein]	28571686
D004958	Estradiol	di-n-hexyl phthalate inhibits the reaction [Estradiol results in increased activity of ESR2 protein]	28571686
D004958	Estradiol	di-n-octyl phthalate inhibits the reaction [Estradiol results in increased activity of ESR2 protein]	28571686
D004958	Estradiol	di-n-pentyl phthalate inhibits the reaction [Estradiol results in increased activity of ESR2 protein]	28571686
D004958	Estradiol	dong quai inhibits the reaction [Estradiol binds to ESR2 protein]	11368622
D004958	Estradiol	Endosulfan promotes the reaction [Estradiol results in increased expression of ESR2 mRNA]	15261991
D004958	Estradiol	ESR2 affects the reaction [Estradiol affects the expression of ESR1 mRNA]	19434490
D004958	Estradiol	ESR2 affects the reaction [Estradiol results in increased expression of KRT19 mRNA]	20160136
D004958	Estradiol	ESR2 protein affects the reaction [Estradiol affects the expression of CCNA2 mRNA]	19434490
D004958	Estradiol	ESR2 protein affects the reaction [Estradiol promotes the reaction [NCOA1 protein binds to NKD1 gene]]	17962382
D004958	Estradiol	ESR2 protein affects the reaction [Estradiol promotes the reaction [NCOA2 protein binds to NKD1 gene]]	17962382
D004958	Estradiol	ESR2 protein affects the reaction [Estradiol promotes the reaction [NCOA2 protein binds to TMEM121B gene]]	17962382
D004958	Estradiol	ESR2 protein affects the reaction [Estradiol results in decreased expression of CDKN1A mRNA]	19434490
D004958	Estradiol	ESR2 protein affects the reaction [Estradiol results in decreased expression of FGFR2 mRNA]	14699072
D004958	Estradiol	ESR2 protein affects the reaction [Estradiol results in decreased expression of PTPRO mRNA]	19095770
D004958	Estradiol	ESR2 protein affects the reaction [Estradiol results in increased expression of BCL2 mRNA]	19264808
D004958	Estradiol	ESR2 protein affects the reaction [Estradiol results in increased expression of IL24 mRNA]	14699072
D004958	Estradiol	ESR2 protein affects the reaction [Estradiol results in increased expression of KLK3 mRNA]	17131305
D004958	Estradiol	ESR2 protein affects the reaction [Estradiol results in increased expression of KRT19 mRNA]	14699072
D004958	Estradiol	ESR2 protein affects the reaction [Estradiol results in increased expression of MMP12 mRNA]	14699072
D004958	Estradiol	ESR2 protein affects the reaction [Estradiol results in increased expression of NKX3-1 mRNA]	17131305
D004958	Estradiol	ESR2 protein affects the reaction [Estradiol results in increased expression of PDCD4 mRNA]	19264808
D004958	Estradiol	ESR2 protein affects the reaction [Estradiol results in increased expression of RLN2 mRNA]	14699072
D004958	Estradiol	ESR2 protein affects the reaction [Estradiol results in increased expression of SMOX mRNA]	14699072
D004958	Estradiol	ESR2 protein affects the reaction [Estradiol results in increased expression of TANK mRNA]	14699072
D004958	Estradiol	ESR2 protein affects the reaction [Estradiol results in increased expression of WISP2 mRNA]	14699072
D004958	Estradiol	ESR2 protein affects the susceptibility to Estradiol	17275032
D004958	Estradiol	ESR2 protein binds to Estradiol	22989670
D004958	Estradiol	ESR2 protein promotes the reaction [Estradiol results in decreased abundance of Reactive Oxygen Species]	20463317
D004958	Estradiol	ESR2 protein promotes the reaction [Estradiol results in decreased expression of ITPR1 mRNA]	19426747
D004958	Estradiol	ESR2 protein promotes the reaction [Estradiol results in increased phosphorylation of MAPK1 protein]	20372779
D004958	Estradiol	ESR2 protein promotes the reaction [Estradiol results in increased phosphorylation of MAPK3 protein]	20372779
D004958	Estradiol	ESR2 protein results in increased susceptibility to Estradiol	21732360
D004958	Estradiol	[ESR2 protein results in increased susceptibility to Estradiol] which results in increased cleavage of CASP3 protein	21732360
D004958	Estradiol	[ESR2 protein results in increased susceptibility to Estradiol] which results in increased cleavage of PARP1 protein	21732360
D004958	Estradiol	[ESR2 protein results in increased susceptibility to Estradiol] which results in increased expression of PTEN protein	21732360
D004958	Estradiol	Estradiol affects the reaction [daidzein metabolite affects the activity of ESR2 protein]	16965913
D004958	Estradiol	Estradiol affects the reaction [Equol affects the activity of ESR2 protein]	16965913
D004958	Estradiol	Estradiol affects the reaction [kaempferol results in increased activity of ESR2 protein]	16118406
D004958	Estradiol	Estradiol affects the reaction [O-desmethylangolensin affects the activity of ESR2 protein]	16965913
D004958	Estradiol	Estradiol affects the reaction [Quercetin results in increased activity of ESR2 protein]	16118406
D004958	Estradiol	Estradiol affects the reaction [tetrahydrodaidzein affects the activity of ESR2 protein]	16965913
D004958	Estradiol	Estradiol analog binds to ESR2 protein	16728493
D004958	Estradiol	Estradiol binds to and affects the folding of and results in increased activity of ESR2 protein	17872378
D004958	Estradiol	Estradiol binds to and results in increased activity of ESR2 protein	14709801\|1593799
D004958	Estradiol	Estradiol binds to ESR2 protein	10964929\|1125896
D004958	Estradiol	[Estradiol binds to ESR2 protein] promotes the reaction [NCOA2 protein binds to CST5 promoter]	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] promotes the reaction [NCOA2 protein binds to HAVCR2 promoter]	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which affects the folding of ESR2 protein	16216903
D004958	Estradiol	[Estradiol binds to ESR2 protein] which binds to NCOA2 protein	15123288
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in decreased expression of ADM mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in decreased expression of ASAP2 mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in decreased expression of BMF mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in decreased expression of CCL3L3 mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in decreased expression of CCL3 mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in decreased expression of CLCF1 mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in decreased expression of CXCL8 mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in decreased expression of DMBT1 mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in decreased expression of FGF2 mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in decreased expression of IGSF9 mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in decreased expression of KLF6 mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in decreased expression of MYC mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in decreased expression of PKP2 mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in decreased expression of PLAU mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in decreased expression of PLEKHF1 mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in decreased expression of TGFB2 mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in decreased expression of TNFRSF21 mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in decreased expression of TRIB1 mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in decreased expression of ZFP36L1 mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of ABCA3 mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of ACVR1C mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of AFF1 mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of AGAP4 mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of AKAP1 mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of ANXA8L1 mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of APOBEC1 mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of ARHGAP18 mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of ARHGAP36 mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of ASB13 mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of ASCL1 mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of ATP6V1C2 mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of B3GNT6 mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of BCL7A mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of BIRC3 mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of BMP4 mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of BPIFB1 mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of BRI3BP mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of C14ORF132 mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of C14ORF180 mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of C3ORF70 mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of CABLES2 mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of CACNA2D2 mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of CACNB4 mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of CALCR mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of CASP7 mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of CASQ2 mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of CD22 mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of CD83 mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of CDH26 mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of CGN mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of CHPT1 mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of CLASP2 mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of CLCNKA mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of CMKLR1 mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of CPN2 mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of CRKL mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of CYP1A2 mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of CYP46A1 mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of CYP4F11 mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of DHRS9 mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of DNAJA4 mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of DPEP3 mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of EGR2 mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of FAM222A mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of FGD5 mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of FGF3 mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of FGFBP2 mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of FGFR3 mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of FGR mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of FKBP4 mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of FOXK1 mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of FUT4 mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of GCH1 mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of GCOM1 mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of GHRHR mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of GJB3 mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of GPRIN2 mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of GREB1 mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of GRTP1 mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of HAR1A mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of HDAC4 mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of HOMER2 mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of HSD11B2 mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of ID2 mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of IGSF11 mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of IL17RB mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of IL24 mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of INPP5A mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of KAZN mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of KCNF1 mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of KCNK6 mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of KRT74 mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of LILRB5 mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of LOX mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of LPAR1 mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of LPL mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of LRP5L mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of LRRC74A mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of MAD1L1 mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of MAG mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of MANEAL mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of MBOAT1 mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of MCF2L2 mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of MED12L mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of METRNL mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of MGAT3 mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of MLPH mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of MRAP2 mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of MUC1 mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of MYB mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of MYL10 mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of MYLK3 mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of MYOG mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of MYOT mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of MYT1L mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of NCOA1 mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of NEFH mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of NPR2 mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of NRIP1 mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of NTN4 mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of ONECUT2 mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of OPRL1 mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of OSBPL5 mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of OTOF mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of PAPPA mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of PAPSS2 mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of PDE4B mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of PDE4C mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of PDZK1 mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of PITX1 mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of PKD2L1 mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of PLA2G4D mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of PLK2 mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of PLOD2 mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of POM121L8P mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of PTGER3 mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of PTH1R mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of RAB36 mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of RAET1L mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of RCAN1 mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of RGL1 mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of RGS19 mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of RNF144B mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of RNF14 mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of RPS6KA2 mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of RUNX3 mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of S1PR1 mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of S1PR3 mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of SATB2 mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of SDC4 mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of SH2D3C mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of SLC16A3 mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of SLC25A19 mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of SLC25A42 mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of SLC6A3 mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of SLC9A3R1 mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of SLC9A3R2 mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of SLCO2A1 mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of SLITRK4 mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of SMTNL2 mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of SNX24 mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of SOCS1 mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of SOX2 mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of SPIRE2 mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of ST3GAL1 mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of STAT4 mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of SYNDIG1 mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of SYNE3 mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of SYTL5 mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of TANK mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of TAS1R1 mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of TBKBP1 mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of TCF21 mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of TESK2 mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of TIMP3 mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of TIPARP mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of TLN2 mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of TMEM121B mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of TMEM132C mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of TMEM246 mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of TP53I3 mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of TPPP mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of TUBA3C mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of TUBA3D mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of TUBA3E mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of UBASH3A mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of UNKL mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of UPF1 mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of VPS8 mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of VXN mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of ZBTB5 mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of ZNF114 mRNA	20404318
D004958	Estradiol	[Estradiol binds to ESR2 protein] which results in increased expression of ZSWIM5 mRNA	20404318
D004958	Estradiol	[Estradiol co-treated with ESR2 protein] results in decreased expression of EGFR mRNA	19347870
D004958	Estradiol	[Estradiol co-treated with ESR2 protein] results in decreased expression of EGFR protein	19347870
D004958	Estradiol	[Estradiol co-treated with ESR2 protein] results in increased expression of BGLAP mRNA	19347870
D004958	Estradiol	[Estradiol co-treated with ESR2 protein] results in increased expression of BSP mRNA	19347870
D004958	Estradiol	[Estradiol co-treated with ESR2 protein] results in increased expression of LTF mRNA	21783566
D004958	Estradiol	[Estradiol co-treated with ESR2 protein] results in increased expression of NOS3 mRNA	14742696
D004958	Estradiol	[Estradiol co-treated with ESR2 protein] results in increased expression of PTGS2 mRNA	19347870
D004958	Estradiol	[Estradiol co-treated with ESR2] results in increased expression of NOS2 mRNA	11583108
D004958	Estradiol	[Estradiol co-treated with ESR2] results in increased expression of NOS3 mRNA	11583108
D004958	Estradiol	Estradiol inhibits the reaction [ESR2 protein affects the expression of CDK5R1 mRNA]	20404318
D004958	Estradiol	Estradiol inhibits the reaction [ESR2 protein affects the expression of TRIM47 mRNA]	20404318
D004958	Estradiol	Estradiol inhibits the reaction [KAT5 protein results in increased activity of ESR2 protein]	23857583
D004958	Estradiol	Estradiol inhibits the reaction [royal jelly binds to ESR2 protein]	17287592
D004958	Estradiol	Estradiol metabolite binds to ESR2 protein	16728493
D004958	Estradiol	Estradiol promotes the reaction [ESR1 protein binds to ESR2 protein]	20061804
D004958	Estradiol	Estradiol promotes the reaction [ESR2 protein affects the expression of ADAMTSL5 mRNA]	20404318
D004958	Estradiol	Estradiol promotes the reaction [ESR2 protein affects the expression of ANO1 mRNA]	20404318
D004958	Estradiol	Estradiol promotes the reaction [ESR2 protein affects the expression of ARHGEF39 mRNA]	20404318
D004958	Estradiol	Estradiol promotes the reaction [ESR2 protein affects the expression of ATP8B3 mRNA]	20404318
D004958	Estradiol	Estradiol promotes the reaction [ESR2 protein affects the expression of CA12 mRNA]	20404318
D004958	Estradiol	Estradiol promotes the reaction [ESR2 protein affects the expression of CACNA1I mRNA]	20404318
D004958	Estradiol	Estradiol promotes the reaction [ESR2 protein affects the expression of CASP7 mRNA]	20404318
D004958	Estradiol	Estradiol promotes the reaction [ESR2 protein affects the expression of CD34 mRNA]	20404318
D004958	Estradiol	Estradiol promotes the reaction [ESR2 protein affects the expression of CHST8 mRNA]	20404318
D004958	Estradiol	Estradiol promotes the reaction [ESR2 protein affects the expression of CLEC4M mRNA]	20404318
D004958	Estradiol	Estradiol promotes the reaction [ESR2 protein affects the expression of COL15A1 mRNA]	20404318
D004958	Estradiol	Estradiol promotes the reaction [ESR2 protein affects the expression of COL18A1 mRNA]	20404318
D004958	Estradiol	Estradiol promotes the reaction [ESR2 protein affects the expression of CRISPLD2 mRNA]	20404318
D004958	Estradiol	Estradiol promotes the reaction [ESR2 protein affects the expression of CST1 mRNA]	20404318
D004958	Estradiol	Estradiol promotes the reaction [ESR2 protein affects the expression of CST5 mRNA]	20404318
D004958	Estradiol	Estradiol promotes the reaction [ESR2 protein affects the expression of CYP19A1 mRNA]	20404318
D004958	Estradiol	Estradiol promotes the reaction [ESR2 protein affects the expression of ELF3 mRNA]	20404318
D004958	Estradiol	Estradiol promotes the reaction [ESR2 protein affects the expression of FGD6 mRNA]	20404318
D004958	Estradiol	Estradiol promotes the reaction [ESR2 protein affects the expression of FIGNL2 mRNA]	20404318
D004958	Estradiol	Estradiol promotes the reaction [ESR2 protein affects the expression of GABBR2 mRNA]	20404318
D004958	Estradiol	Estradiol promotes the reaction [ESR2 protein affects the expression of GALNT12 mRNA]	20404318
D004958	Estradiol	Estradiol promotes the reaction [ESR2 protein affects the expression of GCOM1 mRNA]	20404318
D004958	Estradiol	Estradiol promotes the reaction [ESR2 protein affects the expression of GREB1 mRNA]	20404318
D004958	Estradiol	Estradiol promotes the reaction [ESR2 protein affects the expression of HAVCR2 mRNA]	20404318
D004958	Estradiol	Estradiol promotes the reaction [ESR2 protein affects the expression of HOXD10 mRNA]	20404318
D004958	Estradiol	Estradiol promotes the reaction [ESR2 protein affects the expression of HSPB8 mRNA]	20404318
D004958	Estradiol	Estradiol promotes the reaction [ESR2 protein affects the expression of KIF21A mRNA]	20404318
D004958	Estradiol	Estradiol promotes the reaction [ESR2 protein affects the expression of KRT13 mRNA]	20404318
D004958	Estradiol	Estradiol promotes the reaction [ESR2 protein affects the expression of KRT15 mRNA]	20404318
D004958	Estradiol	Estradiol promotes the reaction [ESR2 protein affects the expression of KRT19 mRNA]	20404318
D004958	Estradiol	Estradiol promotes the reaction [ESR2 protein affects the expression of KRT72 mRNA]	20404318
D004958	Estradiol	Estradiol promotes the reaction [ESR2 protein affects the expression of KRT86 mRNA]	20404318
D004958	Estradiol	Estradiol promotes the reaction [ESR2 protein affects the expression of MDFIC mRNA]	20404318
D004958	Estradiol	Estradiol promotes the reaction [ESR2 protein affects the expression of METRNL mRNA]	20404318
D004958	Estradiol	Estradiol promotes the reaction [ESR2 protein affects the expression of MXD1 mRNA]	20404318
D004958	Estradiol	Estradiol promotes the reaction [ESR2 protein affects the expression of NAV2 mRNA]	20404318
D004958	Estradiol	Estradiol promotes the reaction [ESR2 protein affects the expression of NPR2 mRNA]	20404318
D004958	Estradiol	Estradiol promotes the reaction [ESR2 protein affects the expression of OTOF mRNA]	20404318
D004958	Estradiol	Estradiol promotes the reaction [ESR2 protein affects the expression of PADI4 mRNA]	20404318
D004958	Estradiol	Estradiol promotes the reaction [ESR2 protein affects the expression of PDK4 mRNA]	20404318
D004958	Estradiol	Estradiol promotes the reaction [ESR2 protein affects the expression of PTGER3 mRNA]	20404318
D004958	Estradiol	Estradiol promotes the reaction [ESR2 protein affects the expression of RGS10 mRNA]	20404318
D004958	Estradiol	Estradiol promotes the reaction [ESR2 protein affects the expression of SEMA3F mRNA]	20404318
D004958	Estradiol	Estradiol promotes the reaction [ESR2 protein affects the expression of SH2D3C mRNA]	20404318
D004958	Estradiol	Estradiol promotes the reaction [ESR2 protein affects the expression of SLC25A42 mRNA]	20404318
D004958	Estradiol	Estradiol promotes the reaction [ESR2 protein affects the expression of SLC45A3 mRNA]	20404318
D004958	Estradiol	Estradiol promotes the reaction [ESR2 protein affects the expression of SLC47A2 mRNA]	20404318
D004958	Estradiol	Estradiol promotes the reaction [ESR2 protein affects the expression of SLC6A6 mRNA]	20404318
D004958	Estradiol	Estradiol promotes the reaction [ESR2 protein affects the expression of SPOCD1 mRNA]	20404318
D004958	Estradiol	Estradiol promotes the reaction [ESR2 protein affects the expression of STOX2 mRNA]	20404318
D004958	Estradiol	Estradiol promotes the reaction [ESR2 protein affects the expression of SYBU mRNA]	20404318
D004958	Estradiol	Estradiol promotes the reaction [ESR2 protein affects the expression of TAS1R1 mRNA]	20404318
D004958	Estradiol	Estradiol promotes the reaction [ESR2 protein affects the expression of TH mRNA]	20404318
D004958	Estradiol	Estradiol promotes the reaction [ESR2 protein affects the expression of TNFSF14 mRNA]	20404318
D004958	Estradiol	Estradiol promotes the reaction [ESR2 protein affects the expression of TUBA3D mRNA]	20404318
D004958	Estradiol	Estradiol promotes the reaction [ESR2 protein affects the expression of VASN mRNA]	20404318
D004958	Estradiol	Estradiol promotes the reaction [ESR2 protein affects the expression of ZFP36 mRNA]	20404318
D004958	Estradiol	Estradiol promotes the reaction [ESR2 protein alternative form binds to ESR2 protein alternative form]	16938840
D004958	Estradiol	Estradiol promotes the reaction [ESR2 protein binds to and results in increased activity of NCOA2 protein]	28807876
D004958	Estradiol	Estradiol promotes the reaction [ESR2 protein binds to EZH2 promoter]	25088689
D004958	Estradiol	Estradiol promotes the reaction [ESR2 protein binds to HOXA10 promoter]	15236964
D004958	Estradiol	Estradiol promotes the reaction [ESR2 protein binds to IGF1 promoter]	17872375
D004958	Estradiol	Estradiol promotes the reaction [ESR2 protein binds to KRT19 promoter]	20160136
D004958	Estradiol	Estradiol promotes the reaction [ESR2 protein binds to NCOA1 protein]	10964929
D004958	Estradiol	Estradiol promotes the reaction [ESR2 protein binds to NCOA2 protein]	10964929
D004958	Estradiol	Estradiol promotes the reaction [ESR2 protein binds to NKD1 gene]	17962382
D004958	Estradiol	Estradiol promotes the reaction [ESR2 protein binds to PTGS2 promoter]	17872375
D004958	Estradiol	Estradiol promotes the reaction [ESR2 protein binds to TMEM121B gene]	17962382
D004958	Estradiol	Estradiol promotes the reaction [ESR2 protein results in decreased expression of ADORA2B mRNA]	20404318
D004958	Estradiol	Estradiol promotes the reaction [ESR2 protein results in decreased expression of C9ORF84 mRNA]	20404318
D004958	Estradiol	Estradiol promotes the reaction [ESR2 protein results in decreased expression of IL6 mRNA]	20404318
D004958	Estradiol	Estradiol promotes the reaction [ESR2 protein results in decreased expression of INHBE mRNA]	20404318
D004958	Estradiol	Estradiol promotes the reaction [ESR2 protein results in decreased expression of NOG mRNA]	20404318
D004958	Estradiol	Estradiol promotes the reaction [ESR2 protein results in decreased expression of PDE5A mRNA]	20404318
D004958	Estradiol	Estradiol promotes the reaction [ESR2 protein results in decreased expression of SERTAD4 mRNA]	20404318
D004958	Estradiol	Estradiol promotes the reaction [NCOA1 protein binds to ESR2 protein]	17135255
D004958	Estradiol	Estradiol results in decreased expression of ESR2 mRNA	15130599\|1870080
D004958	Estradiol	Estradiol results in decreased expression of ESR2 mRNA alternative form	16596234
D004958	Estradiol	Estradiol results in decreased expression of ESR2 protein	15118252\|1899782
D004958	Estradiol	Estradiol results in increased activity of [ESR1 protein co-treated with ESR2 protein]	22507746
D004958	Estradiol	Estradiol results in increased activity of ESR2 protein	11335189\|1187533
D004958	Estradiol	Estradiol results in increased activity of ESR2 protein alternative form	17266178
D004958	Estradiol	[Estradiol results in increased activity of ESR2 protein] which results in increased expression of IGFBP4 mRNA	12399409
D004958	Estradiol	[Estradiol results in increased activity of ESR2 protein] which results in increased expression of MT2A mRNA	12399409
D004958	Estradiol	Estradiol results in increased degradation of ESR2 protein	14702340
D004958	Estradiol	Estradiol results in increased expression of ESR2 mRNA	12377985\|1273731
D004958	Estradiol	Estradiol results in increased expression of ESR2 mRNA alternative form	16596234
D004958	Estradiol	Estradiol results in increased expression of ESR2 mRNA mutant form	15207704
D004958	Estradiol	Estradiol results in increased expression of ESR2 protein	14664715\|1673934
D004958	Estradiol	Estradiol results in increased localization of ESR2 protein	15171712
D004958	Estradiol	Estradiol results in increased phosphorylation of and results in increased localization of and results in increased activity of ESR2 protein	20623183
D004958	Estradiol	Estriol inhibits the reaction [Estradiol binds to ESR2 protein]	9751507
D004958	Estradiol	Eugenol inhibits the reaction [Estradiol binds to ESR2 protein]	12495555
D004958	Estradiol	fenarimol promotes the reaction [Estradiol results in increased expression of ESR2 mRNA]	15261991
D004958	Estradiol	fludioxonil inhibits the reaction [Estradiol results in increased expression of ESR2 mRNA]	23436777
D004958	Estradiol	fulvestrant inhibits the reaction [[Estradiol co-treated with ESR2 protein] results in increased expression of NOS3 mRNA]	14742696
D004958	Estradiol	fulvestrant inhibits the reaction [Estradiol results in decreased expression of ESR2 mRNA]	15130599
D004958	Estradiol	fulvestrant inhibits the reaction [Estradiol results in increased activity of ESR2 protein]	15171712\|1793596
D004958	Estradiol	fulvestrant inhibits the reaction [Estradiol results in increased expression of ESR2 mRNA]	18973785\|2686731
D004958	Estradiol	fulvestrant inhibits the reaction [Estradiol results in increased expression of ESR2 protein]	28882636
D004958	Estradiol	fulvestrant inhibits the reaction [Estradiol results in increased localization of ESR2 protein]	15171712
D004958	Estradiol	fulvestrant inhibits the reaction [methoxyacetic acid promotes the reaction [Estradiol results in increased activity of ESR2 protein]]	15103026
D004958	Estradiol	Genistein inhibits the reaction [Estradiol binds to ESR2 protein]	10964929\|1136862
D004958	Estradiol	Genistein promotes the reaction [Estradiol results in increased activity of ESR2 protein]	16118406
D004958	Estradiol	geraniol inhibits the reaction [Estradiol binds to ESR2 protein]	12495555
D004958	Estradiol	hexabrominated diphenyl ether 153 inhibits the reaction [Estradiol results in increased activity of ESR2 protein]	19672399
D004958	Estradiol	kaempferol inhibits the reaction [Estradiol binds to ESR2 protein]	9751507
D004958	Estradiol	lycopene inhibits the reaction [Estradiol results in increased activity of ESR2 protein]	17051425
D004958	Estradiol	methoxyacetic acid promotes the reaction [Estradiol results in increased activity of ESR2 protein]	15103026\|1848617
D004958	Estradiol	Methoxychlor inhibits the reaction [Estradiol binds to ESR2 protein]	9751507
D004958	Estradiol	mono-benzyl phthalate promotes the reaction [Estradiol results in increased activity of ESR2 protein]	28571686
D004958	Estradiol	"N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide inhibits the reaction [Estradiol results in increased expression of ESR2 mRNA]"	23436777
D004958	Estradiol	naringenin inhibits the reaction [Estradiol binds to ESR2 protein]	16566672\|9751507
D004958	Estradiol	pentabrominated diphenyl ether 100 inhibits the reaction [Estradiol results in increased activity of ESR2 protein]	19672399
D004958	Estradiol	Phytoestrogens inhibits the reaction [Estradiol binds to ESR2 protein]	16566672
D004958	Estradiol	Plant Extracts inhibits the reaction [Estradiol binds to ESR2 protein]	11368622
D004958	Estradiol	Polybrominated Biphenyls metabolite inhibits the reaction [Estradiol results in increased activity of ESR2 protein]	19672399
D004958	Estradiol	Polychlorinated Biphenyls metabolite inhibits the reaction [Estradiol results in increased expression of ESR2 mRNA]	12377985
D004958	Estradiol	prochloraz promotes the reaction [Estradiol results in increased expression of ESR2 mRNA]	15261991
D004958	Estradiol	Propolis inhibits the reaction [Estradiol binds to ESR2 protein]	25786527
D004958	Estradiol	Quercetin promotes the reaction [Estradiol results in increased activity of ESR2 protein]	22613215
D004958	Estradiol	resveratrol inhibits the reaction [Estradiol binds to ESR2 protein]	11507064
D004958	Estradiol	resveratrol promotes the reaction [Estradiol results in increased activity of ESR2 protein]	16118406
D004958	Estradiol	royal jelly inhibits the reaction [Estradiol binds to ESR2 protein]	15946813
D004958	Estradiol	SB 203580 inhibits the reaction [[ESR2 protein results in increased susceptibility to Estradiol] which results in increased cleavage of CASP3 protein]	21732360
D004958	Estradiol	SB 203580 inhibits the reaction [[ESR2 protein results in increased susceptibility to Estradiol] which results in increased cleavage of PARP1 protein]	21732360
D004958	Estradiol	Sodium Hypochlorite inhibits the reaction [Estradiol binds to ESR2 protein]	14723943
D004958	Estradiol	Tamoxifen inhibits the reaction [Estradiol results in increased activity of ESR2 protein]	19672399\|2677835
D004958	Estradiol	Tamoxifen inhibits the reaction [Estradiol results in increased expression of ESR2 mRNA]	12377985
D004958	Estradiol	Tetrachlorodibenzodioxin inhibits the reaction [Cycloheximide promotes the reaction [Estradiol results in increased expression of ESR2 mRNA]]	15207704
D004958	Estradiol	Tetrachlorodibenzodioxin inhibits the reaction [Estradiol results in increased expression of ESR2 mRNA]	15207704
D004958	Estradiol	Tetrachlorodibenzodioxin inhibits the reaction [Estradiol results in increased expression of ESR2 mRNA mutant form]	15207704
D004958	Estradiol	tri-(2-ethylhexyl)trimellitate promotes the reaction [Estradiol results in increased activity of ESR2 protein]	16756374
D004958	Estradiol	trichostatin A promotes the reaction [Estradiol results in increased activity of ESR2 protein]	15103026
D004958	Estradiol	Triclosan inhibits the reaction [Estradiol binds to ESR2 protein]	17992702
D004958	Estradiol	triphenyl phosphate metabolite inhibits the reaction [Estradiol results in increased activity of ESR2 protein]	26778350
D004958	Estradiol	Valproic Acid metabolite promotes the reaction [Estradiol results in increased activity of ESR2 protein]	23892311
D004958	Estradiol	Valproic Acid promotes the reaction [Estradiol results in increased activity of ESR2 protein]	15103026\|2389231
D004958	Estradiol	Estradiol binds to ESR2 protein	19913605
D004958	Estradiol	Estradiol affects the reaction [Dieldrin results in decreased expression of ESR2 mRNA]	23041725
D004958	Estradiol	Estradiol results in decreased expression of ESR2 mRNA	18279978
D004958	Estradiol	Estradiol results in increased expression of ESR2 mRNA	18279978
D004958	Estradiol	4-nonylphenol inhibits the reaction [Estradiol results in increased expression of ESR2 mRNA]	22056370
D004958	Estradiol	beta-hexachlorocyclohexane inhibits the reaction [Estradiol binds to ESR2 protein]	21278053
D004958	Estradiol	bisphenol A inhibits the reaction [Estradiol results in increased expression of ESR2 mRNA]	28476547
D004958	Estradiol	bu-zhong-yi-qi-tang inhibits the reaction [Estradiol results in increased expression of ESR2 mRNA]	17089059
D004958	Estradiol	Dieldrin inhibits the reaction [Estradiol binds to ESR2 protein]	21278053
D004958	Estradiol	Endosulfan inhibits the reaction [Estradiol binds to ESR2 protein]	21278053
D004958	Estradiol	ESR2 affects the reaction [[Estradiol co-treated with Progesterone] results in increased expression of OXT mRNA]	12834440
D004958	Estradiol	ESR2 affects the reaction [Estradiol results in decreased expression of ESR1 protein]	11145618
D004958	Estradiol	ESR2 affects the reaction [Estradiol results in increased expression of PGR protein]	11145618
D004958	Estradiol	ESR2 gene mutant form inhibits the reaction [CGA protein results in increased abundance of Estradiol]	20378682
D004958	Estradiol	ESR2 protein affects the susceptibility to Estradiol	11145618
D004958	Estradiol	ESR2 protein alternative form inhibits the reaction [Estradiol results in increased expression of ESR2 protein]	27634370
D004958	Estradiol	ESR2 protein promotes the reaction [Estradiol results in increased expression of LPL mRNA]	17974624
D004958	Estradiol	Estradiol binds to and affects the activity of ESR2 protein alternative form	15924412
D004958	Estradiol	Estradiol binds to ESR2 protein	19913605\|2127805
D004958	Estradiol	"[Estradiol co-treated with 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane] results in decreased expression of ESR2 mRNA"	11509743
D004958	Estradiol	"[Estradiol co-treated with 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane] results in increased expression of ESR2 mRNA"	11509743
D004958	Estradiol	[Estradiol co-treated with Methoxychlor metabolite] results in decreased expression of ESR2 mRNA	11509743
D004958	Estradiol	[Estradiol co-treated with Methoxychlor metabolite] results in increased expression of ESR2 mRNA	11509743
D004958	Estradiol	Estradiol inhibits the reaction [ESR2 protein alternative form results in increased expression of GNRH1 mRNA]	16439454
D004958	Estradiol	Estradiol inhibits the reaction [fulvestrant results in decreased expression of ESR2 mRNA alternative form]	28356238
D004958	Estradiol	Estradiol results in decreased expression of ESR2 mRNA	11509743\|2057491
D004958	Estradiol	Estradiol results in decreased expression of ESR2 protein	17850458\|2847654
D004958	Estradiol	Estradiol results in increased activity of ESR2 protein	19495926
D004958	Estradiol	Estradiol results in increased expression of ESR2 mRNA	14664715\|1660661
D004958	Estradiol	Estradiol results in increased expression of ESR2 protein	14664715\|1591683
D004958	Estradiol	Estradiol results in increased expression of ESR2 protein alternative form	27634370
D004958	Estradiol	fulvestrant inhibits the reaction [ESR2 protein promotes the reaction [Estradiol results in increased expression of LPL mRNA]]	17974624
D004958	Estradiol	NCOA1 protein promotes the reaction [Estradiol results in increased expression of ESR2 protein]	27634370
D004958	Estradiol	NCOA1 protein promotes the reaction [Estradiol results in increased expression of ESR2 protein alternative form]	27634370
D004958	Estradiol	NCOA2 protein inhibits the reaction [ESR2 protein alternative form inhibits the reaction [Estradiol results in increased expression of ESR2 protein]]	27634370
D004958	Estradiol	NCOA2 protein promotes the reaction [Estradiol results in increased expression of ESR2 protein]	27634370
D004958	Estradiol	NCOA2 protein promotes the reaction [Estradiol results in increased expression of ESR2 protein alternative form]	27634370
D004958	Estradiol	NCOA3 protein promotes the reaction [Estradiol results in increased expression of ESR2 protein alternative form]	27634370
D004958	Estradiol	Progesterone inhibits the reaction [ESR2 protein promotes the reaction [Estradiol results in increased expression of LPL mRNA]]	17974624
D004958	Estradiol	Estradiol results in increased expression of ESR2 mRNA	17681682
D004958	Estradiol	[Estradiol co-treated with Tamoxifen] results in increased expression of ESR2 mRNA	17823450
D004958	Estradiol	Estradiol results in increased expression of ESR2 mRNA	17823450\|1870914
D004958	Estradiol	Estradiol results in increased expression of ESR2 mRNA	17258427
D004958	Estradiol	Estradiol results in increased expression of ESR2 mRNA	19101654
D004958	Estradiol	ESR2 protein affects the reaction [Estradiol results in decreased expression of MMP13 mRNA]	17612627
D004958	Estradiol	Estradiol inhibits the reaction [ESR2 protein results in increased expression of MMP13 mRNA]	17612627
D004958	Estradiol	Estradiol results in increased expression of ESR2 mRNA	21145966
D004958	Estradiol	Estradiol binds to ESR2 protein	19913605
D004958	Estradiol	"5,11-diethyl-5,6,11,12-tetrahydrochrysene-2,8-diol inhibits the reaction [Estradiol results in increased activity of ESR2 protein]"	11583108
D004958	Estradiol	afimoxifene inhibits the reaction [Estradiol binds to ESR2 protein alternative form]	9492041
D004958	Estradiol	[alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of ESR2 mRNA]	22389237
D004958	Estradiol	"Androstane-3,17-diol inhibits the reaction [Estradiol binds to ESR2 protein]"	8650195
D004958	Estradiol	[Arsenic co-treated with Estradiol co-treated with Triiodothyronine] results in decreased expression of ESR2 mRNA	27338438
D004958	Estradiol	[bisphenol A co-treated with Estradiol co-treated with Triiodothyronine] results in increased expression of ESR2 mRNA	27338438
D004958	Estradiol	[bisphenol A co-treated with Zearalenone co-treated with Arsenic co-treated with enzacamene co-treated with Estradiol co-treated with Triiodothyronine] results in decreased expression of ESR2 mRNA	27338438
D004958	Estradiol	bisphenol A inhibits the reaction [Estradiol binds to ESR2 protein alternative form]	9492041
D004958	Estradiol	[bisphenol A results in increased susceptibility to [Estradiol co-treated with Triiodothyronine]] which results in increased expression of ESR2 mRNA	27338438
D004958	Estradiol	Coumestrol inhibits the reaction [Estradiol binds to ESR2 protein alternative form]	9492041
D004958	Estradiol	Diethylstilbestrol inhibits the reaction [Estradiol binds to ESR2 protein]	8650195
D004958	Estradiol	[enzacamene co-treated with Estradiol co-treated with Triiodothyronine] affects the expression of ESR2 mRNA	27338438
D004958	Estradiol	ESR1 protein results in decreased susceptibility to [Estradiol co-treated with ESR2 protein]	22166976
D004958	Estradiol	ESR2 protein affects the reaction [Estradiol results in increased expression of SLC6A3 protein]	16451217
D004958	Estradiol	Estradiol affects the expression of ESR2 mRNA	22389237
D004958	Estradiol	Estradiol affects the expression of ESR2 protein	27463640
D004958	Estradiol	Estradiol affects the localization of ESR2 protein	19479021\|2207056
D004958	Estradiol	Estradiol affects the reaction [Oxygen deficiency affects the expression of ESR2 mRNA]	24333797
D004958	Estradiol	Estradiol affects the reaction [Oxygen deficiency affects the expression of ESR2 protein]	24333797
D004958	Estradiol	Estradiol binds to and results in increased activity of ESR2 protein	11014220\|8650195
D004958	Estradiol	Estradiol binds to ESR2 protein	10619402\|1101422
D004958	Estradiol	Estradiol binds to ESR2 protein alternative form	9492041
D004958	Estradiol	[Estradiol co-treated with Progesterone] results in decreased expression of ESR2 mRNA	21277368
D004958	Estradiol	[Estradiol co-treated with Tamoxifen] results in increased expression of ESR2 protein	19460436
D004958	Estradiol	[Estradiol co-treated with Triiodothyronine] inhibits the reaction [bisphenol A results in decreased expression of ESR2 mRNA]	27338438
D004958	Estradiol	[Estradiol co-treated with Triiodothyronine] promotes the reaction [Zearalenone results in decreased expression of ESR2 mRNA]	27338438
D004958	Estradiol	Estradiol inhibits the reaction [16 alpha-iodoestradiol binds to ESR2 protein]	9048584
D004958	Estradiol	Estradiol inhibits the reaction [Oxygen deficiency results in decreased expression of ESR2 mRNA]	24333797
D004958	Estradiol	Estradiol inhibits the reaction [Oxygen deficiency results in decreased expression of ESR2 protein]	24333797
D004958	Estradiol	Estradiol promotes the reaction [ESR2 protein alternative form binds to ESR1 protein]	9492041
D004958	Estradiol	Estradiol promotes the reaction [[ESR2 protein binds to FHL1 promoter] which results in decreased expression of FHL1 mRNA]	20149813
D004958	Estradiol	Estradiol results in decreased expression of ESR2 mRNA	12008023\|1283491
D004958	Estradiol	Estradiol results in decreased expression of ESR2 protein	15548368\|1947902
D004958	Estradiol	Estradiol results in increased activity of ESR2 protein	11583108\|1466279
D004958	Estradiol	Estradiol results in increased expression of ESR2 mRNA	15458797\|1631101
D004958	Estradiol	Estradiol results in increased expression of ESR2 protein	22070562
D004958	Estradiol	Estriol inhibits the reaction [Estradiol binds to ESR2 protein]	8650195
D004958	Estradiol	Estriol inhibits the reaction [Estradiol binds to ESR2 protein alternative form]	9492041
D004958	Estradiol	Estrone inhibits the reaction [Estradiol binds to ESR2 protein]	8650195
D004958	Estradiol	Estrone inhibits the reaction [Estradiol binds to ESR2 protein alternative form]	9492041
D004958	Estradiol	Genistein inhibits the reaction [Estradiol affects the expression of ESR2 mRNA]	17049845
D004958	Estradiol	Genistein inhibits the reaction [Estradiol binds to ESR2 protein alternative form]	9492041
D004958	Estradiol	Methoxychlor inhibits the reaction [Estradiol binds to ESR2 protein alternative form]	9492041
D004958	Estradiol	pentabromodiphenyl ether promotes the reaction [Estradiol results in decreased expression of ESR2 mRNA]	16414171
D004958	Estradiol	Progesterone inhibits the reaction [Estradiol results in increased expression of ESR2 mRNA]	19094096
D004958	Estradiol	Tamoxifen inhibits the reaction [Estradiol binds to ESR2 protein alternative form]	9492041
D004958	Estradiol	Tamoxifen inhibits the reaction [Estradiol results in increased activity of ESR2 protein]	8650195
D004958	Estradiol	[Zearalenone co-treated with Estradiol co-treated with Triiodothyronine] results in decreased expression of ESR2 mRNA	27338438
D004958	Estradiol	[Zearalenone results in increased susceptibility to [Estradiol co-treated with Triiodothyronine]] which results in decreased expression of ESR2 mRNA	27338438
D004958	Estradiol	Estradiol results in increased activity of ESR2 protein	17539551
D004958	Estradiol	Estradiol promotes the reaction [ESR1 protein binds to ESR2 protein]	15891078
D004958	Estradiol	Estradiol promotes the reaction [ESR2 protein binds to ESR2 protein]	15891078
D004958	Estradiol	Estradiol binds to ESR2 protein	19913605
D004958	Estradiol	Estradiol affects the expression of ESR2 protein	15653758\|1668007
D004958	Estradiol	"7,3'-dihydroxy-4'-methoxyisoflavone inhibits the reaction [Estradiol binds to ESR2 protein]"	20686605
D004958	Estradiol	Estradiol binds to and results in increased activity of ESR2 protein	18310284\|1864483
D004958	Estradiol	Estradiol binds to ESR2 protein	20686605
D004958	Estradiol	Estradiol promotes the reaction [PSMC5 protein binds to ESR2 protein]	14702340
D004958	Estradiol	Estradiol results in increased activity of ESR2 protein	22989670
D004958	Estradiol	fulvestrant inhibits the reaction [Estradiol results in increased activity of ESR2 protein]	22989670
C023888	beta-hexachlorocyclohexane	beta-hexachlorocyclohexane results in increased activity of ESR2 protein	15064155
C023888	beta-hexachlorocyclohexane	beta-hexachlorocyclohexane inhibits the reaction [Estradiol binds to ESR2 protein]	21278053
D024503	beta-Tocopherol	[alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of ESR2 mRNA]	22389237
C095105	bexarotene	bexarotene binds to and results in decreased activity of ESR2 protein	25752796
D001639	Bicarbonates	"[2,3-bis(4-hydroxyphenyl)-propionitrile binds to and results in increased activity of ESR2 protein] which results in increased secretion of Bicarbonates"	18499763
C004541	biochanin A	biochanin A binds to and results in increased activity of ESR2 protein	16076101\|9751507
C004541	biochanin A	biochanin A binds to ESR2 protein	12224631\|1656667
C004541	biochanin A	biochanin A inhibits the reaction [Estradiol binds to ESR2 protein]	16566672
C004541	biochanin A	biochanin A binds to ESR2 protein	19913605
C004541	biochanin A	biochanin A binds to ESR2 protein	19913605
C576262	bis(2-ethylhexyl) 2,3,4,5-tetrabromophthalate	"[bis(2-ethylhexyl) 2,3,4,5-tetrabromophthalate co-treated with 2-ethylhexyl 2,3,4,5-tetrabromobenzoate] results in decreased expression of ESR2 mRNA"	25461741
C543008	bis(4-hydroxyphenyl)sulfone	bis(4-hydroxyphenyl)sulfone binds to and results in increased activity of ESR2 protein	27633901
C543008	bis(4-hydroxyphenyl)sulfone	bis(4-hydroxyphenyl)sulfone results in increased activity of [ESR1 protein co-treated with ESR2 protein]	22507746
C543008	bis(4-hydroxyphenyl)sulfone	bis(4-hydroxyphenyl)sulfone results in increased activity of ESR2 protein	23714657
C543008	bis(4-hydroxyphenyl)sulfone	ESR2 gene mutant form results in increased susceptibility to bis(4-hydroxyphenyl)sulfone	28903498
C543008	bis(4-hydroxyphenyl)sulfone	bis(4-hydroxyphenyl)sulfone results in increased expression of ESR2 mRNA	28938450
C543008	bis(4-hydroxyphenyl)sulfone	bis(4-hydroxyphenyl)sulfone results in decreased expression of ESR2 mRNA	28352085
C543008	bis(4-hydroxyphenyl)sulfone	bis(4-hydroxyphenyl)sulfone results in increased expression of ESR2 protein	28352085
C006780	bisphenol A	bisphenol A results in increased expression of ESR2 mRNA	26372180
C006780	bisphenol A	AR protein mutant form affects the reaction [bisphenol A results in decreased expression of ESR2 mRNA]	18007998
C006780	bisphenol A	bisphenol A affects the expression of ESR2	26021997
C006780	bisphenol A	bisphenol A analog binds to and results in decreased activity of ESR2 protein	20427257
C006780	bisphenol A	bisphenol A analog binds to and results in increased activity of ESR2 protein	11335189\|2162294
C006780	bisphenol A	bisphenol A analog binds to ESR2 protein	23768907
C006780	bisphenol A	bisphenol A analog inhibits the reaction [Estradiol binds to and results in increased activity of ESR2 protein]	20427257
C006780	bisphenol A	bisphenol A binds to and results in increased activity of ESR2 protein	11258963\|1276524
C006780	bisphenol A	bisphenol A binds to ESR2 protein	10964929\|1151861
C006780	bisphenol A	[bisphenol A co-treated with ESR2 protein] results in increased expression of LTF mRNA	21783566
C006780	bisphenol A	bisphenol A inhibits the reaction [Estradiol binds to ESR2 protein]	10964929\|1125896
C006780	bisphenol A	bisphenol A inhibits the reaction [Estradiol results in increased expression of ESR2 protein]	20836126
C006780	bisphenol A	bisphenol A inhibits the reaction [KAT5 protein results in decreased activity of ESR2 protein]	23857583
C006780	bisphenol A	bisphenol A promotes the reaction [ESR2 protein binds to EZH2 promoter]	25088689
C006780	bisphenol A	bisphenol A promotes the reaction [ESR2 protein binds to HOTAIR promoter]	24533973
C006780	bisphenol A	bisphenol A promotes the reaction [ESR2 protein binds to NCOA1 protein]	10964929
C006780	bisphenol A	bisphenol A promotes the reaction [ESR2 protein binds to NCOA2 protein]	10964929
C006780	bisphenol A	bisphenol A results in decreased expression of ESR2 mRNA	18007998
C006780	bisphenol A	bisphenol A results in decreased expression of ESR2 protein	18007998\|2322281
C006780	bisphenol A	bisphenol A results in increased activity of [ESR1 protein co-treated with ESR2 protein]	22507746
C006780	bisphenol A	bisphenol A results in increased activity of ESR2 protein	12402979\|1475463
C006780	bisphenol A	bisphenol A results in increased expression of ESR2 mRNA	12737316\|1466471
C006780	bisphenol A	bisphenol A results in increased expression of ESR2 protein	14664715\|2423136
C006780	bisphenol A	ESR2 protein promotes the reaction [bisphenol A results in increased expression of HOTAIR mRNA]	24533973
C006780	bisphenol A	fulvestrant inhibits the reaction [bisphenol A results in increased expression of ESR2 mRNA]	28882636
C006780	bisphenol A	Sodium Hypochlorite inhibits the reaction [bisphenol A binds to ESR2 protein]	14723943
C006780	bisphenol A	bisphenol A affects the activity of ESR2 protein	17222059
C006780	bisphenol A	bisphenol A affects the expression of ESR2	23719926
C006780	bisphenol A	bisphenol A affects the expression of ESR2 mRNA	23716699\|2847654
C006780	bisphenol A	bisphenol A affects the expression of ESR2 protein	28476547
C006780	bisphenol A	bisphenol A affects the localization of ESR2 protein	20950447
C006780	bisphenol A	bisphenol A inhibits the reaction [Estradiol results in increased expression of ESR2 mRNA]	28476547
C006780	bisphenol A	bisphenol A inhibits the reaction [Streptozocin results in decreased expression of ESR2 mRNA]	24781736
C006780	bisphenol A	bisphenol A results in decreased expression of ESR2 mRNA	12505546\|2118293
C006780	bisphenol A	bisphenol A results in decreased expression of ESR2 protein	12505546\|2020618
C006780	bisphenol A	bisphenol A results in increased expression of ESR2 mRNA	14664715\|1496792
C006780	bisphenol A	bisphenol A results in increased expression of ESR2 protein	14664715\|1722249
C006780	bisphenol A	ESR2 promotes the reaction [bisphenol A results in increased secretion of INS1 protein]	22347437
C006780	bisphenol A	ESR2 protein affects the reaction [bisphenol A affects the expression of CACNA1I mRNA]	25958630
C006780	bisphenol A	ESR2 protein affects the reaction [bisphenol A results in increased expression of CACNA1G mRNA]	25958630
C006780	bisphenol A	ESR2 protein affects the reaction [bisphenol A results in increased expression of CACNA1H mRNA]	25958630
C006780	bisphenol A	ESR2 protein alternative form inhibits the reaction [bisphenol A results in increased expression of ESR2 protein]	27634370
C006780	bisphenol A	fulvestrant inhibits the reaction [[[INS protein co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone] co-treated with bisphenol A] results in increased activity of ESR2 protein]	26944108
C006780	bisphenol A	[[INS protein co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone] co-treated with bisphenol A] results in increased activity of ESR2 protein	26944108
C006780	bisphenol A	NCOA1 protein promotes the reaction [bisphenol A results in increased expression of ESR2 protein]	27634370
C006780	bisphenol A	NCOA2 protein promotes the reaction [bisphenol A results in increased expression of ESR2 protein]	27634370
C006780	bisphenol A	bisphenol A results in increased expression of ESR2 mRNA	17681682
C006780	bisphenol A	bisphenol A results in increased expression of ESR2 mRNA	17258427
C006780	bisphenol A	bisphenol A results in decreased expression of ESR2 mRNA	20621667
C006780	bisphenol A	bisphenol A results in increased expression of ESR2 mRNA	28938450
C006780	bisphenol A	bisphenol A results in increased expression of ESR2 protein	14652134
C006780	bisphenol A	bisphenol A affects the expression of ESR2	21112483
C006780	bisphenol A	bisphenol A affects the expression of ESR2 mRNA	23457122\|2435209
C006780	bisphenol A	bisphenol A affects the localization of ESR2 protein	19479021
C006780	bisphenol A	bisphenol A binds to ESR2 protein	15458795\|1991360
C006780	bisphenol A	[bisphenol A co-treated with Estradiol co-treated with Triiodothyronine] results in increased expression of ESR2 mRNA	27338438
C006780	bisphenol A	[bisphenol A co-treated with Genistein] results in decreased expression of ESR2 protein	24884420
C006780	bisphenol A	[bisphenol A co-treated with Zearalenone co-treated with Arsenic co-treated with enzacamene co-treated with Estradiol co-treated with Triiodothyronine] results in decreased expression of ESR2 mRNA	27338438
C006780	bisphenol A	[bisphenol A co-treated with Zearalenone co-treated with Arsenic co-treated with enzacamene] results in increased expression of ESR2 mRNA	27338438
C006780	bisphenol A	bisphenol A inhibits the reaction [Estradiol binds to ESR2 protein alternative form]	9492041
C006780	bisphenol A	bisphenol A metabolite affects the expression of ESR2 mRNA	20435109
C006780	bisphenol A	bisphenol A promotes the reaction [ESR2 protein binds to CAV1 protein]	28067316
C006780	bisphenol A	bisphenol A results in decreased expression of ESR2 mRNA	22101008\|2228535
C006780	bisphenol A	bisphenol A results in decreased expression of ESR2 protein	15548368\|1983709
C006780	bisphenol A	bisphenol A results in increased activity of ESR2 protein	22166976
C006780	bisphenol A	bisphenol A results in increased expression of ESR2	28928807
C006780	bisphenol A	bisphenol A results in increased expression of ESR2 mRNA	11108262\|1281057
C006780	bisphenol A	bisphenol A results in increased expression of ESR2 protein	20692330\|2783000
C006780	bisphenol A	bisphenol A results in increased methylation of ESR2 promoter	21827818
C006780	bisphenol A	[bisphenol A results in increased susceptibility to [Estradiol co-treated with Triiodothyronine]] which results in increased expression of ESR2 mRNA	27338438
C006780	bisphenol A	ESR1 protein results in decreased susceptibility to [bisphenol A co-treated with ESR2 protein]	22166976
C006780	bisphenol A	ESR2 protein results in increased susceptibility to bisphenol A	24140712\|2456994
C006780	bisphenol A	[Estradiol co-treated with Triiodothyronine] inhibits the reaction [bisphenol A results in decreased expression of ESR2 mRNA]	27338438
C006780	bisphenol A	"[Gonadotropins, Equine co-treated with bisphenol A] results in increased expression of ESR2 protein"	28648634
C006780	bisphenol A	bisphenol A binds to ESR2 protein	19913605
C006780	bisphenol A	bisphenol A affects the activity of ESR2 protein	20926581
C006780	bisphenol A	bisphenol A binds to ESR2 protein	11193391
C006780	bisphenol A	bisphenol A inhibits the reaction [PSMC5 protein results in increased ubiquitination of ESR2 protein]	14702340
C006780	bisphenol A	bisphenol A promotes the reaction [ESR2 protein binds to MED1 protein]	14664715
C006780	bisphenol A	bisphenol A results in increased activity of ESR2 protein	11403899
D000069286	Bortezomib	[arsenic trioxide co-treated with Bortezomib] results in decreased expression of ESR2 mRNA	25913414
D000069286	Bortezomib	Bortezomib binds to and results in decreased activity of ESR2 protein	25752796
C023623	brassinolide	brassinolide affects the localization of ESR2 protein	20833159
C023623	brassinolide	brassinolide results in decreased expression of ESR2	20833159
D015124	8-Bromo Cyclic Adenosine Monophosphate	8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of ESR2 mRNA	22079614
C100092	bromophos	bromophos results in increased activity of ESR2 protein	15064155
D002083	Butylated Hydroxyanisole	Butylated Hydroxyanisole binds to ESR2 protein	12822488
D002083	Butylated Hydroxyanisole	Butylated Hydroxyanisole inhibits the reaction [Estradiol binds to ESR2 protein]	12822488
D002083	Butylated Hydroxyanisole	Butylated Hydroxyanisole results in increased activity of ESR2 protein	16756374
C027561	butylbenzyl phthalate	butylbenzyl phthalate binds to and results in decreased activity of ESR2 protein	15840436
C027561	butylbenzyl phthalate	butylbenzyl phthalate binds to and results in increased activity of ESR2 protein	15840436
C027561	butylbenzyl phthalate	butylbenzyl phthalate binds to ESR2 protein	19913605
C027561	butylbenzyl phthalate	butylbenzyl phthalate inhibits the reaction [Estradiol results in increased activity of ESR2 protein]	28571686
C027561	butylbenzyl phthalate	butylbenzyl phthalate results in increased activity of ESR2 protein	28571686
C027561	butylbenzyl phthalate	butylbenzyl phthalate binds to ESR2 protein	19913605
C027561	butylbenzyl phthalate	butylbenzyl phthalate results in decreased activity of ESR2 protein	24994688
C027561	butylbenzyl phthalate	butylbenzyl phthalate results in increased activity of ESR2 protein	11403899
C038091	butylparaben	butylparaben binds to and results in increased activity of ESR2 protein	23567241
C038091	butylparaben	butylparaben binds to ESR2 protein	11193391
C038091	butylparaben	butylparaben results in increased expression of ESR2 mRNA	25128701
C038091	butylparaben	butylparaben results in increased expression of ESR2 protein	25128701
C038091	butylparaben	butylparaben binds to ESR2 protein	20132880
C038091	butylparaben	butylparaben results in decreased expression of ESR2 mRNA	18648085
C038091	butylparaben	butylparaben results in increased expression of ESR2 mRNA	26888303
C018475	butyraldehyde	butyraldehyde results in increased expression of ESR2 mRNA	26079696
D020148	Butyric Acid	Butyric Acid promotes the reaction [Estradiol results in increased activity of ESR2 protein]	15103026
D020148	Butyric Acid	Butyric Acid results in increased expression of ESR2 mRNA	22687346
C402943	bu-zhong-yi-qi-tang	bu-zhong-yi-qi-tang inhibits the reaction [Estradiol results in increased expression of ESR2 mRNA]	17089059
D002104	Cadmium	Cadmium results in increased activity of ESR2 protein	16635015
D019256	Cadmium Chloride	Cadmium Chloride results in decreased expression of ESR2 mRNA	24794047
D019256	Cadmium Chloride	Cadmium Chloride results in decreased expression of ESR2 mRNA	20186393
D019256	Cadmium Chloride	Cadmium Chloride results in decreased expression of ESR2 protein	20186393
D002166	Camptothecin	Camptothecin binds to and results in decreased activity of ESR2 protein	25752796
D012721	Carbaryl	Carbaryl binds to and results in decreased activity of ESR2 protein	16626760
D012721	Carbaryl	Carbaryl results in decreased expression of ESR2 mRNA	27829164
D002251	Carbon Tetrachloride	Carbon Tetrachloride affects the expression of ESR2 mRNA	17805973
C066624	CDRI 85-287	CDRI 85-287 binds to and results in increased activity of ESR2 protein	25655200
C066624	CDRI 85-287	CDRI 85-287 results in increased expression of ESR2 mRNA	25655200
C066624	CDRI 85-287	ESR2 protein affects the reaction [CDRI 85-287 results in increased expression of FASLG mRNA]	25655200
C078669	cedrol	cedrol binds to and results in increased activity of ESR2 protein	27633901
C450419	CHF 4056	CHF 4056 binds to ESR2 protein	11861784
D002706	Chlordan	Chlordan binds to and results in increased activity of ESR2 protein	16626760
D002706	Chlordan	Chlordan results in increased activity of ESR2 protein	15064155
D007631	Chlordecone	Chlordecone binds to and results in decreased activity of ESR2 protein	16626760
D007631	Chlordecone	Chlordecone binds to ESR2 protein	12224631\|9751507
D007631	Chlordecone	Chlordecone inhibits the reaction [Estradiol binds to ESR2 protein]	9751507
D020111	Chlorodiphenyl (54% Chlorine)	Chlorodiphenyl (54% Chlorine) results in increased expression of ESR2	21664404
D020111	Chlorodiphenyl (54% Chlorine)	Chlorodiphenyl (54% Chlorine) results in increased expression of ESR2 protein	24216299
D020111	Chlorodiphenyl (54% Chlorine)	Chlorodiphenyl (54% Chlorine) results in decreased expression of ESR2 mRNA	16414171
C004663	chloropropylate	chloropropylate results in increased activity of ESR2 protein	15064155
D004390	Chlorpyrifos	Chlorpyrifos results in increased expression of ESR2 mRNA	25889763
D002839	Chromans	Chromans analog results in decreased activity of ESR2 protein	15737489
C074702	chromium hexavalent ion	chromium hexavalent ion results in increased expression of ESR2 mRNA	21316074
C074702	chromium hexavalent ion	Ascorbic Acid inhibits the reaction [chromium hexavalent ion results in decreased expression of ESR2 mRNA]	18602937
C074702	chromium hexavalent ion	chromium hexavalent ion results in decreased expression of ESR2 mRNA	18602937\|2162160
D002911	Chrysenes	[Chrysenes binds to and results in decreased activity of ESR2 protein] inhibits the reaction [amurensin G results in increased phosphorylation of NOS3 protein]	22982565
D002911	Chrysenes	Chrysenes binds to and results in decreased activity of ESR2 protein	22982565
C043561	chrysin	chrysin binds to and results in increased activity of ESR2 protein	9751507
C043561	chrysin	chrysin binds to ESR2 protein	12224631
C475575	Cimicifuga extract BNO 1055	Cimicifuga extract BNO 1055 affects the expression of ESR2 mRNA	19350480
C007076	citral	citral binds to ESR2 protein	12495555
C007076	citral	citral inhibits the reaction [Estradiol binds to ESR2 protein]	12495555
D002996	Clomiphene	Clomiphene binds to and results in decreased activity of ESR2 protein	25752796
D002996	Clomiphene	Clomiphene binds to ESR2 protein	12224631
D002996	Clomiphene	Clomiphene inhibits the reaction [16 alpha-iodoestradiol binds to ESR2 protein]	9048584
D002996	Clomiphene	Clomiphene results in increased activity of ESR2 protein	19211805
D003033	Coal Tar	Coal Tar results in decreased expression of ESR2 mRNA	27858113
D005576	Colforsin	Colforsin inhibits the reaction [ESR2 gene mutant form inhibits the reaction [CGA protein results in increased abundance of Cyclic AMP]]	20378682
D003300	Copper	[Copper co-treated with Dietary Sucrose] results in increased expression of ESR2 mRNA	26033743
D003300	Copper	Copper deficiency results in increased expression of ESR2 mRNA	26033743
D003375	Coumestrol	Coumestrol binds to and results in increased activity of ESR2 protein	12765243\|1508475
D003375	Coumestrol	Coumestrol binds to ESR2 protein	11518614\|1222463
D003375	Coumestrol	Coumestrol inhibits the reaction [Estradiol binds to ESR2 protein]	16566672\|9751507
D003375	Coumestrol	Coumestrol results in increased activity of ESR2 protein	16118406
D003375	Coumestrol	ESR2 protein affects the reaction [[Coumestrol co-treated with ESR1 protein] results in increased expression of ADRA2A mRNA]	18310284
D003375	Coumestrol	ESR2 protein affects the reaction [[Coumestrol co-treated with ESR1 protein] results in increased expression of ANLN mRNA]	18310284
D003375	Coumestrol	ESR2 protein affects the reaction [[Coumestrol co-treated with ESR1 protein] results in increased expression of ANP32E mRNA]	18310284
D003375	Coumestrol	ESR2 protein affects the reaction [[Coumestrol co-treated with ESR1 protein] results in increased expression of ASPM mRNA]	18310284
D003375	Coumestrol	ESR2 protein affects the reaction [[Coumestrol co-treated with ESR1 protein] results in increased expression of AURKA mRNA]	18310284
D003375	Coumestrol	ESR2 protein affects the reaction [[Coumestrol co-treated with ESR1 protein] results in increased expression of BIN3 mRNA]	18310284
D003375	Coumestrol	ESR2 protein affects the reaction [[Coumestrol co-treated with ESR1 protein] results in increased expression of CCNA2 mRNA]	18310284
D003375	Coumestrol	ESR2 protein affects the reaction [[Coumestrol co-treated with ESR1 protein] results in increased expression of CDCA3 mRNA]	18310284
D003375	Coumestrol	ESR2 protein affects the reaction [[Coumestrol co-treated with ESR1 protein] results in increased expression of CENPF mRNA]	18310284
D003375	Coumestrol	ESR2 protein affects the reaction [[Coumestrol co-treated with ESR1 protein] results in increased expression of CLCC1 mRNA]	18310284
D003375	Coumestrol	ESR2 protein affects the reaction [[Coumestrol co-treated with ESR1 protein] results in increased expression of CTNNAL1 mRNA]	18310284
D003375	Coumestrol	ESR2 protein affects the reaction [[Coumestrol co-treated with ESR1 protein] results in increased expression of CXCL12 mRNA]	18310284
D003375	Coumestrol	ESR2 protein affects the reaction [[Coumestrol co-treated with ESR1 protein] results in increased expression of DEPDC1B mRNA]	18310284
D003375	Coumestrol	ESR2 protein affects the reaction [[Coumestrol co-treated with ESR1 protein] results in increased expression of DEPDC1 mRNA]	18310284
D003375	Coumestrol	ESR2 protein affects the reaction [[Coumestrol co-treated with ESR1 protein] results in increased expression of DHRS2 mRNA]	18310284
D003375	Coumestrol	ESR2 protein affects the reaction [[Coumestrol co-treated with ESR1 protein] results in increased expression of EXOSC9 mRNA]	18310284
D003375	Coumestrol	ESR2 protein affects the reaction [[Coumestrol co-treated with ESR1 protein] results in increased expression of FABP5 mRNA]	18310284
D003375	Coumestrol	ESR2 protein affects the reaction [[Coumestrol co-treated with ESR1 protein] results in increased expression of FCMR mRNA]	18310284
D003375	Coumestrol	ESR2 protein affects the reaction [[Coumestrol co-treated with ESR1 protein] results in increased expression of FHL1 mRNA]	18310284
D003375	Coumestrol	ESR2 protein affects the reaction [[Coumestrol co-treated with ESR1 protein] results in increased expression of GAL mRNA]	18310284
D003375	Coumestrol	ESR2 protein affects the reaction [[Coumestrol co-treated with ESR1 protein] results in increased expression of GPSM2 mRNA]	18310284
D003375	Coumestrol	ESR2 protein affects the reaction [[Coumestrol co-treated with ESR1 protein] results in increased expression of GREB1 mRNA]	18310284
D003375	Coumestrol	ESR2 protein affects the reaction [[Coumestrol co-treated with ESR1 protein] results in increased expression of GTSE1 mRNA]	18310284
D003375	Coumestrol	ESR2 protein affects the reaction [[Coumestrol co-treated with ESR1 protein] results in increased expression of HMGB2 mRNA]	18310284
D003375	Coumestrol	ESR2 protein affects the reaction [[Coumestrol co-treated with ESR1 protein] results in increased expression of HMMR mRNA]	18310284
D003375	Coumestrol	ESR2 protein affects the reaction [[Coumestrol co-treated with ESR1 protein] results in increased expression of IGFBP4 mRNA]	18310284
D003375	Coumestrol	ESR2 protein affects the reaction [[Coumestrol co-treated with ESR1 protein] results in increased expression of IL17RB mRNA]	18310284
D003375	Coumestrol	ESR2 protein affects the reaction [[Coumestrol co-treated with ESR1 protein] results in increased expression of IL20 mRNA]	18310284
D003375	Coumestrol	ESR2 protein affects the reaction [[Coumestrol co-treated with ESR1 protein] results in increased expression of IRS1 mRNA]	18310284
D003375	Coumestrol	ESR2 protein affects the reaction [[Coumestrol co-treated with ESR1 protein] results in increased expression of KCNK5 mRNA]	18310284
D003375	Coumestrol	ESR2 protein affects the reaction [[Coumestrol co-treated with ESR1 protein] results in increased expression of KIF18A mRNA]	18310284
D003375	Coumestrol	ESR2 protein affects the reaction [[Coumestrol co-treated with ESR1 protein] results in increased expression of MKI67 mRNA]	18310284
D003375	Coumestrol	ESR2 protein affects the reaction [[Coumestrol co-treated with ESR1 protein] results in increased expression of MYB mRNA]	18310284
D003375	Coumestrol	ESR2 protein affects the reaction [[Coumestrol co-treated with ESR1 protein] results in increased expression of MYC mRNA]	18310284
D003375	Coumestrol	ESR2 protein affects the reaction [[Coumestrol co-treated with ESR1 protein] results in increased expression of NCAPG mRNA]	18310284
D003375	Coumestrol	ESR2 protein affects the reaction [[Coumestrol co-treated with ESR1 protein] results in increased expression of NEK2 mRNA]	18310284
D003375	Coumestrol	ESR2 protein affects the reaction [[Coumestrol co-treated with ESR1 protein] results in increased expression of NPY1R mRNA]	18310284
D003375	Coumestrol	ESR2 protein affects the reaction [[Coumestrol co-treated with ESR1 protein] results in increased expression of NUSAP1 mRNA]	18310284
D003375	Coumestrol	ESR2 protein affects the reaction [[Coumestrol co-treated with ESR1 protein] results in increased expression of PDLIM3 mRNA]	18310284
D003375	Coumestrol	ESR2 protein affects the reaction [[Coumestrol co-treated with ESR1 protein] results in increased expression of PDZK1 mRNA]	18310284
D003375	Coumestrol	ESR2 protein affects the reaction [[Coumestrol co-treated with ESR1 protein] results in increased expression of PIF1 mRNA]	18310284
D003375	Coumestrol	ESR2 protein affects the reaction [[Coumestrol co-treated with ESR1 protein] results in increased expression of PKIB mRNA]	18310284
D003375	Coumestrol	ESR2 protein affects the reaction [[Coumestrol co-treated with ESR1 protein] results in increased expression of PLK1 mRNA]	18310284
D003375	Coumestrol	ESR2 protein affects the reaction [[Coumestrol co-treated with ESR1 protein] results in increased expression of RACGAP1 mRNA]	18310284
D003375	Coumestrol	ESR2 protein affects the reaction [[Coumestrol co-treated with ESR1 protein] results in increased expression of RASGRP1 mRNA]	18310284
D003375	Coumestrol	ESR2 protein affects the reaction [[Coumestrol co-treated with ESR1 protein] results in increased expression of RERG mRNA]	18310284
D003375	Coumestrol	ESR2 protein affects the reaction [[Coumestrol co-treated with ESR1 protein] results in increased expression of SLC26A2 mRNA]	18310284
D003375	Coumestrol	ESR2 protein affects the reaction [[Coumestrol co-treated with ESR1 protein] results in increased expression of SPC25 mRNA]	18310284
D003375	Coumestrol	ESR2 protein affects the reaction [[Coumestrol co-treated with ESR1 protein] results in increased expression of ST8SIA6 mRNA]	18310284
D003375	Coumestrol	ESR2 protein affects the reaction [[Coumestrol co-treated with ESR1 protein] results in increased expression of STC2 mRNA]	18310284
D003375	Coumestrol	ESR2 protein affects the reaction [[Coumestrol co-treated with ESR1 protein] results in increased expression of TFF1 mRNA]	18310284
D003375	Coumestrol	ESR2 protein affects the reaction [[Coumestrol co-treated with ESR1 protein] results in increased expression of TMPRSS3 mRNA]	18310284
D003375	Coumestrol	ESR2 protein affects the reaction [[Coumestrol co-treated with ESR1 protein] results in increased expression of TRAF4 mRNA]	18310284
D003375	Coumestrol	ESR2 protein affects the susceptibility to Coumestrol	17275032
D003375	Coumestrol	ESR2 protein promotes the reaction [[Coumestrol co-treated with ESR1 protein] results in increased expression of CDKN2C mRNA]	18310284
D003375	Coumestrol	ESR2 protein promotes the reaction [[Coumestrol co-treated with ESR1 protein] results in increased expression of CDKN3 mRNA]	18310284
D003375	Coumestrol	ESR2 protein promotes the reaction [[Coumestrol co-treated with ESR1 protein] results in increased expression of KIF14 mRNA]	18310284
D003375	Coumestrol	ESR2 protein promotes the reaction [[Coumestrol co-treated with ESR1 protein] results in increased expression of KIF15 mRNA]	18310284
D003375	Coumestrol	ESR2 protein promotes the reaction [[Coumestrol co-treated with ESR1 protein] results in increased expression of KIF20A mRNA]	18310284
D003375	Coumestrol	ESR2 protein promotes the reaction [[Coumestrol co-treated with ESR1 protein] results in increased expression of TOP2A mRNA]	18310284
D003375	Coumestrol	Coumestrol binds to ESR2 protein	19913605
D003375	Coumestrol	Coumestrol results in increased expression of ESR2 protein	21708076\|2763437
D003375	Coumestrol	Coumestrol results in increased expression of ESR2 protein alternative form	27634370
D003375	Coumestrol	ESR2 protein affects the reaction [Coumestrol results in increased expression of SOD2 protein]	23526725
D003375	Coumestrol	ESR2 protein affects the susceptibility to Coumestrol	23526725
D003375	Coumestrol	Coumestrol binds to ESR2 protein	19913605
D003375	Coumestrol	Coumestrol inhibits the reaction [16 alpha-iodoestradiol binds to ESR2 protein]	9048584
D003375	Coumestrol	Coumestrol inhibits the reaction [Estradiol binds to ESR2 protein alternative form]	9492041
D003375	Coumestrol	Coumestrol binds to and results in increased activity of ESR2 protein	18310284
D003471	Cuprizone	Cuprizone results in decreased expression of ESR2 mRNA	27523638
C007168	cyanazine	cyanazine binds to ESR2 protein	12224631
C002488	cyanophenphos	cyanophenphos results in increased activity of ESR2 protein	15064155
D003513	Cycloheximide	Cycloheximide promotes the reaction [Estradiol results in increased expression of ESR2 mRNA]	15207704
D003513	Cycloheximide	Tetrachlorodibenzodioxin inhibits the reaction [Cycloheximide promotes the reaction [Estradiol results in increased expression of ESR2 mRNA]]	15207704
D003520	Cyclophosphamide	[Doxorubicin co-treated with Cyclophosphamide] results in increased expression of ESR2 mRNA	16322899
C037304	cyhalothrin	cyhalothrin results in decreased expression of ESR2 mRNA	18419197
C037304	cyhalothrin	cyhalothrin results in decreased expression of ESR2 protein	18419197
C017160	cypermethrin	cypermethrin results in increased expression of ESR2 mRNA	20574910
C004742	daidzein	daidzein inhibits the reaction [Estradiol results in increased expression of ESR2 mRNA]	20043933
C004742	daidzein	daidzein results in increased expression of ESR2 mRNA	20043933
C004742	daidzein	daidzein binds to and results in increased activity of ESR2 protein	16076101\|9751507
C004742	daidzein	daidzein binds to ESR2 protein	12224631\|1599374
C004742	daidzein	[daidzein co-treated with ESR2 protein] results in decreased expression of EGFR mRNA	19347870
C004742	daidzein	[daidzein co-treated with ESR2 protein] results in decreased expression of EGFR protein	19347870
C004742	daidzein	[daidzein co-treated with ESR2 protein] results in increased expression of BGLAP mRNA	19347870
C004742	daidzein	[daidzein co-treated with ESR2 protein] results in increased expression of BSP mRNA	19347870
C004742	daidzein	[daidzein co-treated with ESR2 protein] results in increased expression of PTGS2 mRNA	19347870
C004742	daidzein	daidzein inhibits the reaction [Estradiol binds to ESR2 protein]	16566672
C004742	daidzein	daidzein inhibits the reaction [KAT5 protein results in increased activity of ESR2 protein]	23857583
C004742	daidzein	daidzein metabolite binds to and results in increased activity of ESR2 protein	15084758
C004742	daidzein	daidzein promotes the reaction [Estradiol results in increased activity of ESR2 protein]	16118406
C004742	daidzein	daidzein results in increased activity of ESR2 protein	16118406\|1893707
C004742	daidzein	daidzein results in increased activity of ESR2 protein alternative form	17266178
C004742	daidzein	daidzein results in increased expression of ESR2 mRNA	16033089
C004742	daidzein	daidzein results in increased expression of ESR2 protein	16033089
C004742	daidzein	ESR2 affects the reaction [daidzein results in increased expression of CDKN1A]	21161820
C004742	daidzein	ESR2 affects the susceptibility to daidzein	21161820
C004742	daidzein	ESR2 gene polymorphism affects the reaction [[Genistein co-treated with daidzein] affects the expression of VCAM1 protein]	16332659
C004742	daidzein	ESR2 gene polymorphism affects the susceptibility to [Genistein co-treated with daidzein]	16332659
C004742	daidzein	Estradiol affects the reaction [daidzein metabolite affects the activity of ESR2 protein]	16965913
C004742	daidzein	daidzein binds to ESR2 protein	19913605
C004742	daidzein	daidzein results in increased activity of ESR2 protein	19495926
C004742	daidzein	daidzein results in increased expression of ESR2 protein	27634370
C004742	daidzein	daidzein binds to ESR2 protein	19913605
C004742	daidzein	daidzein results in increased expression of ESR2 mRNA	29217487
C004742	daidzein	daidzein results in increased expression of ESR2 protein	29217487
C004742	daidzein	[Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in increased expression of ESR2 mRNA	28964809
C004742	daidzein	daidzein results in increased expression of ESR2 mRNA	19617652
C004742	daidzein	daidzein results in increased expression of ESR2 protein	19617652
C004742	daidzein	daidzein affects the activity of ESR2 protein	20926581
C004742	daidzein	daidzein results in increased activity of ESR2 protein	11403899
C013908	daidzin	[Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in increased expression of ESR2 mRNA	28964809
D003634	DDT	DDT results in increased expression of ESR2 mRNA	26372180
D003634	DDT	DDT binds to and results in increased activity of ESR2 protein	16626760
D003634	DDT	DDT results in increased activity of ESR2 protein	15064155\|2613924
D003634	DDT	DDT results in increased activity of ESR2 protein	9860891
D003634	DDT	"[o,p'-DDT co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Methoxychlor co-treated with Endosulfan co-treated with DDT] results in increased activity of ESR2 protein"	9860891
C014347	decitabine	[decitabine co-treated with trichostatin A] results in decreased methylation of ESR2 promoter	19331143
C014347	decitabine	[decitabine co-treated with trichostatin A] results in increased expression of ESR2 mRNA	19331143
C014347	decitabine	decitabine promotes the reaction [trichostatin A results in increased expression of ESR2 mRNA]	18092350
C014347	decitabine	decitabine promotes the reaction [trichostatin A results in increased expression of ESR2 protein]	18092350
C014347	decitabine	decitabine results in decreased expression of ESR2 mRNA	19027819
C014347	decitabine	decitabine results in decreased methylation of ESR2 promoter	19331143
C014347	decitabine	decitabine results in increased expression of ESR2 mRNA	17625110\|1933114
D003671	DEET	[fipronil co-treated with DEET] results in decreased expression of ESR2 mRNA	27091632
D003687	Dehydroepiandrosterone	Dehydroepiandrosterone binds to and results in increased activity of ESR2 protein	15994348
D003687	Dehydroepiandrosterone	Dehydroepiandrosterone results in increased expression of ESR2 mRNA	17823450\|1870914
C086916	delta-hexachlorocyclohexane	delta-hexachlorocyclohexane results in increased activity of ESR2 protein	15064155
C479072	delta-tocopherol	[alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of ESR2 mRNA]	22389237
D003907	Dexamethasone	fulvestrant inhibits the reaction [[[INS protein co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone] co-treated with bisphenol A] results in increased activity of ESR2 protein]	26944108
D003907	Dexamethasone	[[INS protein co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone] co-treated with bisphenol A] results in increased activity of ESR2 protein	26944108
D003907	Dexamethasone	[[INS protein co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone] co-treated with Diethylstilbestrol] results in decreased activity of ESR2 protein	26944108
C042791	di-(5-methylhexyl)phthalate	di-(5-methylhexyl)phthalate results in decreased activity of ESR2 protein	24994688
D036381	Diarylheptanoids	Diarylheptanoids results in increased activity of ESR2 protein	19654927
D036381	Diarylheptanoids	fulvestrant inhibits the reaction [Diarylheptanoids results in increased activity of ESR2 protein]	19654927
C492519	diarylpropionitrile	diarylpropionitrile binds to and results in increased activity of ESR2 protein	15585566
C492519	diarylpropionitrile	diarylpropionitrile inhibits the reaction [KAT5 protein results in decreased activity of ESR2 protein]	23857583
C492519	diarylpropionitrile	diarylpropionitrile inhibits the reaction [KAT5 protein results in increased activity of ESR2 protein]	23857583
C492519	diarylpropionitrile	diarylpropionitrile results in increased activity of ESR2 protein	17935960\|2871710
C492519	diarylpropionitrile	dicyclohexyl phthalate inhibits the reaction [diarylpropionitrile results in increased activity of ESR2 protein]	28717100
C492519	diarylpropionitrile	fulvestrant inhibits the reaction [diarylpropionitrile results in increased activity of ESR2 protein]	17935960
C492519	diarylpropionitrile	diarylpropionitrile results in increased expression of ESR2 mRNA	15236189
C492519	diarylpropionitrile	ESR2 protein affects the reaction [diarylpropionitrile results in increased expression of SOD2 protein]	23526725
C492519	diarylpropionitrile	ESR2 protein affects the susceptibility to diarylpropionitrile	23526725
C492519	diarylpropionitrile	diarylpropionitrile affects the localization of ESR2 protein	22070562
C492519	diarylpropionitrile	diarylpropionitrile binds to and results in increased activity of ESR2 protein	15910780\|2478232
C492519	diarylpropionitrile	[diarylpropionitrile binds to and results in increased activity of ESR2 protein] which results in increased expression of SLC1A2 protein	24782323
C492519	diarylpropionitrile	diarylpropionitrile results in increased expression of ESR2 mRNA	21127968
C492519	diarylpropionitrile	diarylpropionitrile results in increased expression of ESR2 protein	22070562
C492519	diarylpropionitrile	diarylpropionitrile binds to and results in increased activity of ESR2 protein	15615701\|1591213
D003993	Dibutyl Phthalate	Dibutyl Phthalate analog binds to ESR2 protein	15464722
D003993	Dibutyl Phthalate	Dibutyl Phthalate inhibits the reaction [Estradiol results in increased activity of ESR2 protein]	28571686
D003993	Dibutyl Phthalate	Dibutyl Phthalate binds to ESR2 protein	19913605
D003993	Dibutyl Phthalate	Dibutyl Phthalate binds to ESR2 protein	15458795
D003993	Dibutyl Phthalate	Dibutyl Phthalate results in decreased expression of ESR2 mRNA	24067674
D003993	Dibutyl Phthalate	Dibutyl Phthalate results in decreased expression of ESR2 protein	24067674
C011445	dichlofenthion	dichlofenthion results in increased activity of ESR2 protein	15064155
D002945	Cisplatin	Cisplatin results in decreased expression of ESR2 mRNA	23956100
D002945	Cisplatin	ESR2 protein inhibits the reaction [Cisplatin results in increased expression of and results in increased phosphorylation of CDC25C protein]	20623183
D002945	Cisplatin	ESR2 protein inhibits the reaction [Cisplatin results in increased expression of BRCA1 mRNA]	20623183
D002945	Cisplatin	ESR2 protein inhibits the reaction [Cisplatin results in increased expression of BRCA1 protein]	20623183
D002945	Cisplatin	ESR2 protein inhibits the reaction [Cisplatin results in increased phosphorylation of CHEK1 protein]	20623183
D002945	Cisplatin	ESR2 protein promotes the reaction [Cisplatin results in increased expression of CASP2 protein]	20623183
D002945	Cisplatin	ESR2 protein promotes the reaction [Cisplatin results in increased expression of CASP3 protein]	20623183
D002945	Cisplatin	ESR2 protein results in increased susceptibility to Cisplatin	20623183
D002945	Cisplatin	TP53 protein inhibits the reaction [ESR2 protein results in increased susceptibility to Cisplatin]	20623183
D003632	Dichlorodiphenyldichloroethane	Dichlorodiphenyldichloroethane analog results in increased activity of ESR2 protein	15064155
D003633	Dichlorodiphenyl Dichloroethylene	Dichlorodiphenyl Dichloroethylene results in increased expression of ESR2 mRNA	26372180
D003633	Dichlorodiphenyl Dichloroethylene	Dichlorodiphenyl Dichloroethylene analog results in increased activity of ESR2 protein	15064155
D003633	Dichlorodiphenyl Dichloroethylene	Dichlorodiphenyl Dichloroethylene binds to ESR2 protein	17713618
D003633	Dichlorodiphenyl Dichloroethylene	Dichlorodiphenyl Dichloroethylene results in increased activity of ESR2 protein	9860891
D003633	Dichlorodiphenyl Dichloroethylene	"[o,p'-DDT co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Methoxychlor co-treated with Endosulfan co-treated with DDT] results in increased activity of ESR2 protein"	9860891
D004010	Dicofol	Dicofol results in increased activity of ESR2 protein	15064155
C036042	dicyclohexyl phthalate	dicyclohexyl phthalate binds to and results in decreased activity of ESR2 protein	15840436
C036042	dicyclohexyl phthalate	dicyclohexyl phthalate inhibits the reaction [diarylpropionitrile results in increased activity of ESR2 protein]	28717100
C036042	dicyclohexyl phthalate	dicyclohexyl phthalate inhibits the reaction [Estradiol results in increased activity of ESR2 protein]	28571686\|2871710
C036042	dicyclohexyl phthalate	dicyclohexyl phthalate results in decreased activity of ESR2 protein	24994688
D019259	Lamivudine	[Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in decreased expression of ESR2 mRNA	16931933
D019259	Lamivudine	[Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of ESR2 mRNA	16931933
D004026	Dieldrin	Dieldrin binds to and results in decreased activity of ESR2 protein	16626760
D004026	Dieldrin	Dieldrin promotes the reaction [Estradiol results in increased expression of ESR2 mRNA]	15261991
D004026	Dieldrin	Dieldrin results in decreased expression of ESR2 mRNA	20438755\|2304172
D004026	Dieldrin	Estradiol affects the reaction [Dieldrin results in decreased expression of ESR2 mRNA]	23041725
D004026	Dieldrin	Dieldrin inhibits the reaction [Estradiol binds to ESR2 protein]	21278053
D004028	Dienestrol	Dienestrol inhibits the reaction [16 alpha-iodoestradiol binds to ESR2 protein]	9048584
D004041	Dietary Fats	Dietary Fats results in decreased expression of ESR2 protein	26408789
D004041	Dietary Fats	Diosgenin inhibits the reaction [Dietary Fats results in decreased expression of ESR2 protein]	26408789
D004041	Dietary Fats	Dietary Fats results in increased expression of ESR2 mRNA	22010203
D019422	Dietary Sucrose	[Copper co-treated with Dietary Sucrose] results in increased expression of ESR2 mRNA	26033743
D019422	Dietary Sucrose	Dietary Sucrose results in increased expression of ESR2 mRNA	26033743
D004051	Diethylhexyl Phthalate	Diethylhexyl Phthalate binds to and results in decreased activity of ESR2 protein	15840436\|2763390
D004051	Diethylhexyl Phthalate	Diethylhexyl Phthalate binds to and results in increased activity of ESR2 protein	27633901
D004051	Diethylhexyl Phthalate	Diethylhexyl Phthalate inhibits the reaction [Estradiol results in increased activity of ESR2 protein]	28571686
D004051	Diethylhexyl Phthalate	Diethylhexyl Phthalate results in increased expression of ESR2 mRNA	25975992
D004051	Diethylhexyl Phthalate	Diethylhexyl Phthalate results in decreased expression of ESR2 mRNA	28871463
D004051	Diethylhexyl Phthalate	Diethylhexyl Phthalate results in decreased activity of ESR2 protein	24994688
C007379	diethyl phthalate	diethyl phthalate analog binds to ESR2 protein	15464722
D004054	Diethylstilbestrol	Diethylstilbestrol results in increased expression of ESR2 mRNA	26372180
D004054	Diethylstilbestrol	Diethylstilbestrol binds to and results in increased activity of ESR2 protein	12765243
D004054	Diethylstilbestrol	Diethylstilbestrol binds to ESR2 protein	10964929\|1151861
D004054	Diethylstilbestrol	[Diethylstilbestrol binds to ESR2 protein] which binds to NCOA2 protein	15123288
D004054	Diethylstilbestrol	[Diethylstilbestrol co-treated with ESR2 protein] results in increased expression of LTF mRNA	21783566
D004054	Diethylstilbestrol	Diethylstilbestrol inhibits the reaction [Estradiol binds to ESR2 protein]	10964929\|9751507
D004054	Diethylstilbestrol	Diethylstilbestrol promotes the reaction [ESR2 protein alternative form binds to ESR2 protein alternative form]	16938840
D004054	Diethylstilbestrol	Diethylstilbestrol promotes the reaction [ESR2 protein binds to EZH2 promoter]	25088689
D004054	Diethylstilbestrol	Diethylstilbestrol promotes the reaction [ESR2 protein binds to HOTAIR promoter]	24533973
D004054	Diethylstilbestrol	Diethylstilbestrol promotes the reaction [ESR2 protein binds to HOXA10 promoter]	15236964
D004054	Diethylstilbestrol	Diethylstilbestrol promotes the reaction [ESR2 protein binds to NCOA1 protein]	10964929
D004054	Diethylstilbestrol	Diethylstilbestrol promotes the reaction [ESR2 protein binds to NCOA2 protein]	10964929
D004054	Diethylstilbestrol	Diethylstilbestrol results in increased activity of ESR2 protein	19161236
D004054	Diethylstilbestrol	ESR2 protein promotes the reaction [Diethylstilbestrol results in increased expression of HOTAIR mRNA]	24533973
D004054	Diethylstilbestrol	Diethylstilbestrol affects the activity of ESR2 protein	15451043
D004054	Diethylstilbestrol	Diethylstilbestrol binds to and results in increased activity of ESR2 protein	15465114
D004054	Diethylstilbestrol	Diethylstilbestrol binds to ESR2 protein	19913605
D004054	Diethylstilbestrol	Diethylstilbestrol results in increased expression of ESR2 mRNA	22100434\|2271002
D004054	Diethylstilbestrol	Diethylstilbestrol results in increased expression of ESR2 protein	16468032\|2763437
D004054	Diethylstilbestrol	Diethylstilbestrol results in increased expression of ESR2 protein alternative form	27634370
D004054	Diethylstilbestrol	ESR2 protein affects the reaction [Diethylstilbestrol results in decreased expression of SVS4 mRNA]	22275727
D004054	Diethylstilbestrol	ESR2 protein alternative form inhibits the reaction [Diethylstilbestrol results in increased expression of ESR2 protein]	27634370
D004054	Diethylstilbestrol	[[INS protein co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone] co-treated with Diethylstilbestrol] results in decreased activity of ESR2 protein	26944108
D004054	Diethylstilbestrol	Diethylstilbestrol results in increased expression of ESR2 mRNA	17823450
D004054	Diethylstilbestrol	Diethylstilbestrol results in increased expression of ESR2 protein	14652134
D004054	Diethylstilbestrol	Diethylstilbestrol binds to ESR2 protein	19913605
D004054	Diethylstilbestrol	Diethylstilbestrol inhibits the reaction [16 alpha-iodoestradiol binds to ESR2 protein]	9048584
D004054	Diethylstilbestrol	Diethylstilbestrol inhibits the reaction [Estradiol binds to ESR2 protein]	8650195
D004054	Diethylstilbestrol	Diethylstilbestrol results in increased expression of ESR2 mRNA	11108262
D004054	Diethylstilbestrol	Diethylstilbestrol binds to ESR2 protein	19913605
D004054	Diethylstilbestrol	Diethylstilbestrol affects the activity of ESR2 protein	20926581
D004074	Digitoxin	Digitoxin binds to and results in decreased activity of ESR2 protein	25752796
C089799	diheptyl phthalate	diheptyl phthalate analog binds to ESR2 protein	15464722
C025605	diisobutyl phthalate	diisobutyl phthalate binds to and results in increased activity of ESR2 protein	27633901
C025605	diisobutyl phthalate	diisobutyl phthalate inhibits the reaction [Estradiol results in increased activity of ESR2 protein]	28571686
C025605	diisobutyl phthalate	diisobutyl phthalate results in increased activity of ESR2 protein	28571686
D004117	Dimethoate	Dimethoate results in increased expression of ESR2 mRNA	23943137
C027387	di-n-hexyl phthalate	di-n-hexyl phthalate analog binds to ESR2 protein	15464722
C027387	di-n-hexyl phthalate	di-n-hexyl phthalate binds to and results in decreased activity of ESR2 protein	15840436
C027387	di-n-hexyl phthalate	di-n-hexyl phthalate inhibits the reaction [Estradiol results in increased activity of ESR2 protein]	28571686
C027387	di-n-hexyl phthalate	di-n-hexyl phthalate results in decreased activity of ESR2 protein	24994688
C010715	di-n-octyl phthalate	di-n-octyl phthalate analog binds to ESR2 protein	15464722
C010715	di-n-octyl phthalate	di-n-octyl phthalate inhibits the reaction [Estradiol results in increased activity of ESR2 protein]	28571686
C034171	di-n-pentyl phthalate	di-n-pentyl phthalate analog binds to ESR2 protein	15464722
C034171	di-n-pentyl phthalate	di-n-pentyl phthalate binds to and results in decreased activity of ESR2 protein	15840436
C034171	di-n-pentyl phthalate	di-n-pentyl phthalate inhibits the reaction [Estradiol results in increased activity of ESR2 protein]	28571686
C034171	di-n-pentyl phthalate	di-n-pentyl phthalate results in decreased activity of ESR2 protein	24994688
C106479	di-n-propylphthalate	di-n-propylphthalate analog binds to ESR2 protein	15464722
D004144	Diosgenin	Diosgenin inhibits the reaction [Dietary Fats results in decreased expression of ESR2 protein]	26408789
D004144	Diosgenin	Diosgenin promotes the reaction [RXRA protein binds to ESR2 protein]	26408789
D004144	Diosgenin	Diosgenin results in increased expression of ESR2 protein	26408789
C004839	dioxybenzone	dioxybenzone binds to and results in increased activity of ESR2 protein	16079615
C109695	dong quai	dong quai binds to ESR2 protein	11368622
C109695	dong quai	dong quai inhibits the reaction [Estradiol binds to ESR2 protein]	11368622
D004317	Doxorubicin	Doxorubicin binds to and results in decreased activity of ESR2 protein	25752796
D004317	Doxorubicin	[Doxorubicin co-treated with Cyclophosphamide] results in increased expression of ESR2 mRNA	16322899
D004317	Doxorubicin	Doxorubicin results in decreased expression of ESR2 mRNA	23956100
D004317	Doxorubicin	Doxorubicin results in increased expression of ESR2 mRNA	16900372
D004318	Doxycycline	Doxycycline results in increased expression of ESR2	22989670
C118667	dronedarone	dronedarone binds to and results in decreased activity of ESR2 protein	25752796
D004365	Drugs, Chinese Herbal	"Drugs, Chinese Herbal binds to and affects the folding of and results in increased activity of ESR2 protein"	17095596
D004365	Drugs, Chinese Herbal	"Drugs, Chinese Herbal promotes the reaction [ESR2 protein binds to KRT19 promoter]"	17095596
D004365	Drugs, Chinese Herbal	"Drugs, Chinese Herbal results in increased activity of ESR2 protein"	22613215
D004640	Emetine	Emetine binds to and results in decreased activity of ESR2 protein	25752796
D004642	Emodin	Emodin results in increased activity of ESR2 protein	19161236
D004726	Endosulfan	[Endosulfan affects the activity of ESR2 protein] promotes the reaction [LIF protein results in increased activity of STAT3 protein]	14975756
D004726	Endosulfan	Endosulfan binds to and results in decreased activity of ESR2 protein	16626760
D004726	Endosulfan	Endosulfan promotes the reaction [Estradiol results in increased expression of ESR2 mRNA]	15261991
D004726	Endosulfan	Endosulfan results in increased activity of ESR2 protein	15064155\|2613924
D004726	Endosulfan	Endosulfan inhibits the reaction [Estradiol binds to ESR2 protein]	21278053
D004726	Endosulfan	Endosulfan binds to ESR2 protein	19913605
D004726	Endosulfan	Endosulfan results in increased activity of ESR2 protein	9860891
D004726	Endosulfan	"[o,p'-DDT co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Methoxychlor co-treated with Endosulfan co-treated with DDT] results in increased activity of ESR2 protein"	9860891
D004726	Endosulfan	Endosulfan binds to ESR2 protein	19913605
D004732	Endrin	Endrin binds to and results in decreased activity of ESR2 protein	16626760
D004732	Endrin	Endrin results in increased activity of ESR2 protein	26139245
C038939	enzacamene	enzacamene binds to and results in increased activity of ESR2 protein	16079615
C038939	enzacamene	enzacamene binds to ESR2 protein	15147785
C038939	enzacamene	enzacamene results in increased activity of ESR2 protein	12765243
C038939	enzacamene	[bisphenol A co-treated with Zearalenone co-treated with Arsenic co-treated with enzacamene co-treated with Estradiol co-treated with Triiodothyronine] results in decreased expression of ESR2 mRNA	27338438
C038939	enzacamene	[bisphenol A co-treated with Zearalenone co-treated with Arsenic co-treated with enzacamene] results in increased expression of ESR2 mRNA	27338438
C038939	enzacamene	[enzacamene co-treated with Estradiol co-treated with Triiodothyronine] affects the expression of ESR2 mRNA	27338438
D015251	Epirubicin	Epirubicin binds to and results in decreased activity of ESR2 protein	25752796
C045651	epigallocatechin gallate	epigallocatechin gallate results in decreased expression of ESR2 mRNA	20706672
D060754	Equol	Equol binds to and results in increased activity of ESR2 protein	15084758
D060754	Equol	Equol binds to ESR2 protein	12224631\|1599374
D060754	Equol	Equol inhibits the reaction [KAT5 protein results in decreased activity of ESR2 protein]	23857583
D060754	Equol	Equol inhibits the reaction [KAT5 protein results in increased activity of ESR2 protein]	23857583
D060754	Equol	Equol results in increased activity of ESR2 protein	16118406
D060754	Equol	Estradiol affects the reaction [Equol affects the activity of ESR2 protein]	16965913
D060754	Equol	Equol affects the activity of ESR2 protein	20926581
D060754	Equol	Equol binds to and results in increased activity of ESR2 protein	22449546
C478102	ERB 041	ERB 041 results in increased activity of ESR2 protein	25106122\|2613924
C074283	estradiol 3-benzoate	estradiol 3-benzoate affects the expression of ESR2 mRNA	19350480
C074283	estradiol 3-benzoate	estradiol 3-benzoate results in decreased expression of ESR2	15375486
C074283	estradiol 3-benzoate	estradiol 3-benzoate results in decreased expression of ESR2 mRNA	24352099
C074283	estradiol 3-benzoate	estradiol 3-benzoate results in increased expression of ESR2 mRNA	27830003
C074283	estradiol 3-benzoate	estradiol 3-benzoate binds to and results in increased activity of ESR2 protein	17133264
C015854	estradiol valerate	estradiol valerate results in decreased expression of ESR2 protein	17532555
D004964	Estriol	Estriol results in increased expression of ESR2 mRNA	26372180
D004964	Estriol	Estriol binds to and results in increased activity of ESR2 protein	12547825
D004964	Estriol	Estriol binds to ESR2 protein	11518614\|1672849
D004964	Estriol	Estriol inhibits the reaction [Estradiol binds to ESR2 protein]	9751507
D004964	Estriol	Estriol binds to ESR2 protein	19913605
D004964	Estriol	Estriol binds to ESR2 protein	19913605
D004964	Estriol	Estriol binds to ESR2 protein	19913605
D004964	Estriol	Estriol inhibits the reaction [16 alpha-iodoestradiol binds to ESR2 protein]	9048584
D004964	Estriol	Estriol inhibits the reaction [Estradiol binds to ESR2 protein]	8650195
D004964	Estriol	Estriol inhibits the reaction [Estradiol binds to ESR2 protein alternative form]	9492041
D004967	Estrogens	ESR2 protein affects the reaction [Estrogens results in increased expression of VDR mRNA]	15664452
D004967	Estrogens	Estrogens results in increased activity of ESR2 protein polymorphism	28013213
D004967	Estrogens	fulvestrant inhibits the reaction [Estrogens results in increased activity of ESR2 protein polymorphism]	28013213
D004966	Estrogens, Conjugated (USP)	"Estrogens, Conjugated (USP) affects the expression of ESR2 protein"	15653758\|1668007
D004970	Estrone	Estrone results in increased expression of ESR2 mRNA	26372180
D004970	Estrone	Estrone binds to ESR2 protein	11518614\|1991360
D004970	Estrone	Estrone binds to ESR2 protein	19913605
D004970	Estrone	Estrone affects the localization of ESR2 protein	20950447
D004970	Estrone	Estrone binds to ESR2 protein	19913605
D004970	Estrone	Estrone inhibits the reaction [16 alpha-iodoestradiol binds to ESR2 protein]	9048584
D004970	Estrone	Estrone inhibits the reaction [Estradiol binds to ESR2 protein]	8650195
D004970	Estrone	Estrone inhibits the reaction [Estradiol binds to ESR2 protein alternative form]	9492041
D004970	Estrone	Estrone results in increased activity of ESR2 protein	8650195
D004970	Estrone	Estrone results in increased activity of ESR2 protein	17539551
D004970	Estrone	Estrone binds to ESR2 protein	19913605
D000431	Ethanol	Ethanol inhibits the reaction [Melatonin results in decreased expression of ESR2 protein]	23591044
D000431	Ethanol	Ethanol results in decreased expression of ESR2 protein	23591044
D000431	Ethanol	[Melatonin co-treated with Ethanol] results in increased expression of ESR2 protein	23591044
D000431	Ethanol	Melatonin inhibits the reaction [Ethanol results in decreased expression of ESR2 protein]	23591044
D004997	Ethinyl Estradiol	Ethinyl Estradiol results in increased activity of ESR2 protein	12387416
D004997	Ethinyl Estradiol	Ethinyl Estradiol results in increased expression of ESR2 mRNA	26372180
D004997	Ethinyl Estradiol	Ethinyl Estradiol binds to and results in increased activity of ESR2 protein	25752796
D004997	Ethinyl Estradiol	Ethinyl Estradiol binds to ESR2 protein	11518614\|1222463
D004997	Ethinyl Estradiol	Ethinyl Estradiol inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of ESR2 protein]	10633228
D004997	Ethinyl Estradiol	Ethinyl Estradiol promotes the reaction [ESR2 protein alternative form binds to ESR2 protein alternative form]	16938840
D004997	Ethinyl Estradiol	Ethinyl Estradiol results in increased activity of ESR2 protein	12387416
D004997	Ethinyl Estradiol	Ethinyl Estradiol results in increased expression of ESR2 protein	10633228
D004997	Ethinyl Estradiol	Ethinyl Estradiol binds to ESR2 protein	19913605
D004997	Ethinyl Estradiol	Ethinyl Estradiol binds to ESR2 protein	19913605
D004997	Ethinyl Estradiol	Ethinyl Estradiol inhibits the reaction [Streptozocin results in decreased expression of ESR2 mRNA]	24781736
D004997	Ethinyl Estradiol	Ethinyl Estradiol results in increased expression of ESR2 mRNA	16606610\|2478173
D004997	Ethinyl Estradiol	[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of ESR2 mRNA	17942748
D004997	Ethinyl Estradiol	[Ethinyl Estradiol co-treated with letrozole] results in increased expression of ESR2 mRNA	21963593
D004997	Ethinyl Estradiol	Ethinyl Estradiol results in decreased expression of ESR2 mRNA	21963593
D004997	Ethinyl Estradiol	Ethinyl Estradiol results in increased expression of ESR2 mRNA	24992288
D004997	Ethinyl Estradiol	Ethinyl Estradiol results in decreased expression of ESR2 mRNA	17222921
D004997	Ethinyl Estradiol	Ethinyl Estradiol affects the expression of ESR2 mRNA	16551644
D004997	Ethinyl Estradiol	Ethinyl Estradiol binds to ESR2 protein	19913605
D004997	Ethinyl Estradiol	[Ethinyl Estradiol co-treated with Triclosan] results in decreased expression of ESR2 mRNA	23261820
D004997	Ethinyl Estradiol	Ethinyl Estradiol results in decreased expression of ESR2 mRNA	12834913\|2018639
D004997	Ethinyl Estradiol	Ethinyl Estradiol results in decreased expression of ESR2 protein	14709816\|2018639
D004997	Ethinyl Estradiol	Ethinyl Estradiol results in increased expression of ESR2 mRNA	16183386
D004997	Ethinyl Estradiol	fulvestrant inhibits the reaction [[Ethinyl Estradiol co-treated with Triclosan] results in decreased expression of ESR2 mRNA]	23261820
D004997	Ethinyl Estradiol	Ethinyl Estradiol affects the expression of ESR2	17539551
D004997	Ethinyl Estradiol	Ethinyl Estradiol results in decreased expression of ESR2 mRNA	17875331
D004997	Ethinyl Estradiol	Ethinyl Estradiol binds to ESR2 protein	19913605
D004997	Ethinyl Estradiol	Ethinyl Estradiol analog binds to ESR2 protein	15041288
D004997	Ethinyl Estradiol	Ethinyl Estradiol binds to ESR2 protein	15041288
D008656	Mestranol	Mestranol binds to ESR2 protein	12224631
C100038	ethion	ethion results in increased activity of ESR2 protein	15064155
C041062	ethyl bromophos	ethyl bromophos results in increased activity of ESR2 protein	15064155
C451418	ethyl cinnamate	ethyl cinnamate binds to and results in increased activity of ESR2 protein	16079615
C032396	ethyl myristate	ethyl myristate binds to and results in decreased activity of ESR2 protein	27633901
C012313	ethyl-p-hydroxybenzoate	ethyl-p-hydroxybenzoate binds to and results in increased activity of ESR2 protein	23567241
C012313	ethyl-p-hydroxybenzoate	ethyl-p-hydroxybenzoate binds to ESR2 protein	11193391
C012313	ethyl-p-hydroxybenzoate	ethyl-p-hydroxybenzoate binds to ESR2 protein	20132880
D005047	Etoposide	ESR2 protein results in increased susceptibility to Etoposide	20623183
D005047	Etoposide	TP53 protein inhibits the reaction [ESR2 protein results in increased susceptibility to Etoposide]	20623183
D005054	Eugenol	Eugenol binds to ESR2 protein	12495555
D005054	Eugenol	Eugenol inhibits the reaction [Estradiol binds to ESR2 protein]	12495555
D015025	Zearalenone	Zearalenone analog binds to ESR2 protein	28807876
D015025	Zearalenone	Zearalenone analog promotes the reaction [ESR2 protein binds to and results in increased activity of NCOA2 protein]	28807876
D015025	Zearalenone	Zearalenone binds to and results in decreased activity of ESR2 protein	15084758
D015025	Zearalenone	Zearalenone binds to and results in increased activity of ESR2 protein	9751507
D015025	Zearalenone	Zearalenone binds to ESR2 protein	15169976\|1991360
D015025	Zearalenone	Zearalenone promotes the reaction [ESR2 protein binds to and results in increased activity of NCOA2 protein]	28807876
D015025	Zearalenone	Zearalenone binds to ESR2 protein	19913605
D015025	Zearalenone	[bisphenol A co-treated with Zearalenone co-treated with Arsenic co-treated with enzacamene co-treated with Estradiol co-treated with Triiodothyronine] results in decreased expression of ESR2 mRNA	27338438
D015025	Zearalenone	[bisphenol A co-treated with Zearalenone co-treated with Arsenic co-treated with enzacamene] results in increased expression of ESR2 mRNA	27338438
D015025	Zearalenone	[Estradiol co-treated with Triiodothyronine] promotes the reaction [Zearalenone results in decreased expression of ESR2 mRNA]	27338438
D015025	Zearalenone	Zearalenone binds to ESR2 protein	19913605
D015025	Zearalenone	[Zearalenone co-treated with Estradiol co-treated with Triiodothyronine] results in decreased expression of ESR2 mRNA	27338438
D015025	Zearalenone	Zearalenone results in decreased expression of ESR2 mRNA	27338438
D015025	Zearalenone	[Zearalenone results in increased susceptibility to [Estradiol co-treated with Triiodothyronine]] which results in decreased expression of ESR2 mRNA	27338438
D015025	Zearalenone	Zearalenone binds to ESR2 protein	22898043\|2451281
C033789	fenarimol	fenarimol promotes the reaction [Estradiol results in increased expression of ESR2 mRNA]	15261991
C033789	fenarimol	fenarimol results in increased activity of ESR2 protein	15064155\|2681205
C033789	fenarimol	fenarimol results in increased expression of ESR2 mRNA	15261991
C033789	fenarimol	fenarimol results in increased expression of ESR2 mRNA	21722721
C504383	fenbuconazole	fenbuconazole binds to and results in increased activity of ESR2 protein	16626760
C017690	fenvalerate	fenvalerate binds to and results in increased activity of ESR2 protein	16626760
C082360	fipronil	[fipronil co-treated with DEET] results in decreased expression of ESR2 mRNA	27091632
C082360	fipronil	fipronil results in decreased expression of ESR2 mRNA	27091632
C043562	flavone	flavone binds to ESR2 protein	12224631
C108339	fludioxonil	"[fludioxonil co-treated with N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide co-treated with propamocarb] results in increased activity of ESR2 protein"	26812056
C108339	fludioxonil	"[fludioxonil co-treated with N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide] results in increased activity of ESR2 protein"	26812056
C108339	fludioxonil	fludioxonil inhibits the reaction [Estradiol results in increased expression of ESR2 mRNA]	23436777
C108339	fludioxonil	fludioxonil results in decreased expression of ESR2 mRNA	23052036
C108339	fludioxonil	fludioxonil results in increased activity of ESR2 protein	26812056
C108339	fludioxonil	fludioxonil results in increased expression of ESR2 mRNA	23436777
D005485	Flutamide	Flutamide results in increased expression of ESR2 mRNA	21128595
D005485	Flutamide	Flutamide results in decreased expression of ESR2 mRNA	11509743
D005485	Flutamide	Flutamide results in increased expression of ESR2 mRNA	11509743
D005485	Flutamide	Flutamide results in decreased expression of ESR2 mRNA	24992288
D005485	Flutamide	Flutamide affects the expression of ESR2 mRNA	17222921
D005485	Flutamide	Flutamide results in increased expression of ESR2 mRNA	16003321
D005485	Flutamide	Flutamide results in increased expression of ESR2 protein	16003321
C007768	formononetin	formononetin binds to and results in increased activity of ESR2 protein	16076101\|9751507
C007768	formononetin	formononetin binds to ESR2 protein	12224631\|1677353
C070081	fulvestrant	6-OH-BDE-47 promotes the reaction [fulvestrant results in decreased expression of ESR2 protein]	26988655
C070081	fulvestrant	ESR2 protein results in increased susceptibility to fulvestrant	17638070
C070081	fulvestrant	fulvestrant affects the expression of ESR2 protein	19270784
C070081	fulvestrant	fulvestrant binds to and results in decreased activity of ESR2 protein	15537743\|2575279
C070081	fulvestrant	fulvestrant binds to ESR2 protein	17203231\|1991360
C070081	fulvestrant	"fulvestrant inhibits the reaction [2,2',4,4'-tetrabromodiphenyl ether results in increased expression of ESR2 protein]"	26988655
C070081	fulvestrant	"fulvestrant inhibits the reaction [3,3',4,5'-tetrahydroxystilbene results in increased activity of ESR2 protein]"	17935960
C070081	fulvestrant	"fulvestrant inhibits the reaction [Androstane-3,17-diol analog binds to and results in increased activity of ESR2 protein]"	17003281
C070081	fulvestrant	"fulvestrant inhibits the reaction [Androstane-3,17-diol binds to and results in increased activity of ESR2 protein]"	17003281
C070081	fulvestrant	fulvestrant inhibits the reaction [bisphenol A results in increased expression of ESR2 mRNA]	28882636
C070081	fulvestrant	fulvestrant inhibits the reaction [Diarylheptanoids results in increased activity of ESR2 protein]	19654927
C070081	fulvestrant	fulvestrant inhibits the reaction [diarylpropionitrile results in increased activity of ESR2 protein]	17935960
C070081	fulvestrant	fulvestrant inhibits the reaction [Dihydrotestosterone results in increased activity of ESR2 protein]	15171712
C070081	fulvestrant	fulvestrant inhibits the reaction [Dihydrotestosterone results in increased localization of ESR2 protein]	15171712
C070081	fulvestrant	fulvestrant inhibits the reaction [[Estradiol co-treated with ESR2 protein] results in increased expression of NOS3 mRNA]	14742696
C070081	fulvestrant	fulvestrant inhibits the reaction [Estradiol results in decreased expression of ESR2 mRNA]	15130599
C070081	fulvestrant	fulvestrant inhibits the reaction [Estradiol results in increased activity of ESR2 protein]	15171712\|1793596
C070081	fulvestrant	fulvestrant inhibits the reaction [Estradiol results in increased expression of ESR2 mRNA]	18973785\|2686731
C070081	fulvestrant	fulvestrant inhibits the reaction [Estradiol results in increased expression of ESR2 protein]	28882636
C070081	fulvestrant	fulvestrant inhibits the reaction [Estradiol results in increased localization of ESR2 protein]	15171712
C070081	fulvestrant	fulvestrant inhibits the reaction [Genistein results in increased expression of ESR2 protein]	24685904
C070081	fulvestrant	fulvestrant inhibits the reaction [methoxyacetic acid promotes the reaction [Estradiol results in increased activity of ESR2 protein]]	15103026
C070081	fulvestrant	fulvestrant inhibits the reaction [Plant Preparations results in increased activity of ESR2 protein]	17935960
C070081	fulvestrant	fulvestrant inhibits the reaction [prochloraz results in decreased expression of ESR2 mRNA]	15130599
C070081	fulvestrant	fulvestrant inhibits the reaction [resveratrol results in increased activity of ESR2 protein]	17935960
C070081	fulvestrant	fulvestrant inhibits the reaction [rhapontigenin analog results in increased activity of ESR2 protein]	17692514\|1793596
C070081	fulvestrant	fulvestrant promotes the reaction [5-OH-BDE-47 results in decreased expression of ESR2 protein]	26988655
C070081	fulvestrant	fulvestrant promotes the reaction [6-OH-BDE-47 affects the expression of ESR2 protein]	26988655
C070081	fulvestrant	fulvestrant promotes the reaction [ESR1 protein binds to ESR2 protein]	20061804
C070081	fulvestrant	fulvestrant results in decreased expression of ESR2 protein	15950373\|1620292
C070081	fulvestrant	fulvestrant results in increased expression of ESR2 protein	28882636
C070081	fulvestrant	Estradiol inhibits the reaction [fulvestrant results in decreased expression of ESR2 mRNA alternative form]	28356238
C070081	fulvestrant	fulvestrant binds to ESR2 protein	19913605
C070081	fulvestrant	fulvestrant inhibits the reaction [ESR2 protein promotes the reaction [Estradiol results in increased expression of LPL mRNA]]	17974624
C070081	fulvestrant	fulvestrant inhibits the reaction [Estrogens results in increased activity of ESR2 protein polymorphism]	28013213
C070081	fulvestrant	fulvestrant inhibits the reaction [[[INS protein co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone] co-treated with bisphenol A] results in increased activity of ESR2 protein]	26944108
C070081	fulvestrant	fulvestrant results in decreased expression of ESR2 mRNA alternative form	28356238
C070081	fulvestrant	fulvestrant binds to and results in decreased activity of ESR2 protein	19570671\|2478232
C070081	fulvestrant	fulvestrant binds to ESR2 protein	19913605
C070081	fulvestrant	fulvestrant inhibits the reaction [16 alpha-iodoestradiol binds to ESR2 protein]	9048584
C070081	fulvestrant	fulvestrant inhibits the reaction [[Ethinyl Estradiol co-treated with Triclosan] results in decreased expression of ESR2 mRNA]	23261820
C070081	fulvestrant	fulvestrant inhibits the reaction [naringin results in increased expression of ESR2 mRNA]	23596885
C070081	fulvestrant	"fulvestrant inhibits the reaction [[4-nonylphenol co-treated with 3,4,3',4'-tetrachlorobiphenyl] results in decreased expression of ESR2 mRNA]"	17291011
C070081	fulvestrant	fulvestrant binds to ESR2 protein	19913605
C070081	fulvestrant	fulvestrant binds to and results in decreased activity of ESR2 protein	18559275\|2148441
C070081	fulvestrant	fulvestrant inhibits the reaction [1-hydroxypyrene results in increased activity of ESR2 protein]	22989670
C070081	fulvestrant	fulvestrant inhibits the reaction [1-naphthol results in increased activity of ESR2 protein]	22989670
C070081	fulvestrant	fulvestrant inhibits the reaction [9-phenanthrol results in increased activity of ESR2 protein]	22989670
C070081	fulvestrant	fulvestrant inhibits the reaction [Estradiol results in increased activity of ESR2 protein]	22989670
C033119	galaxolide	galaxolide binds to and results in decreased activity of ESR2 protein	15537743
C025473	gamma-sitosterol	gamma-sitosterol binds to ESR2 protein	11518614\|1991360
D024504	gamma-Tocopherol	[alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of ESR2 mRNA]	22389237
C419708	gefitinib	gefitinib results in increased expression of ESR2 protein	20005069
D019833	Genistein	"2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane inhibits the reaction [Genistein binds to and results in increased activity of ESR2 protein]"	11861976
D019833	Genistein	beta Carotene inhibits the reaction [Genistein results in increased activity of ESR2 protein]	17051425
D019833	Genistein	ESR2 affects the reaction [Genistein results in increased expression of CDKN1A]	21161820
D019833	Genistein	ESR2 affects the susceptibility to Genistein	21161820
D019833	Genistein	ESR2 gene polymorphism affects the reaction [[Genistein co-treated with daidzein] affects the expression of VCAM1 protein]	16332659
D019833	Genistein	ESR2 gene polymorphism affects the susceptibility to [Genistein co-treated with daidzein]	16332659
D019833	Genistein	ESR2 promotes the reaction [Genistein results in decreased expression of ABAT protein]	20884965
D019833	Genistein	ESR2 promotes the reaction [Genistein results in decreased expression of ACLY protein]	20884965
D019833	Genistein	ESR2 promotes the reaction [Genistein results in decreased expression of ACOX1 protein]	20884965
D019833	Genistein	ESR2 promotes the reaction [Genistein results in decreased expression of ADSL protein]	20884965
D019833	Genistein	ESR2 promotes the reaction [Genistein results in decreased expression of ANXA1 protein]	20884965
D019833	Genistein	ESR2 promotes the reaction [Genistein results in decreased expression of ANXA3 protein]	20884965
D019833	Genistein	ESR2 promotes the reaction [Genistein results in decreased expression of ARMCX3 protein]	20884965
D019833	Genistein	ESR2 promotes the reaction [Genistein results in decreased expression of BAG5 protein]	20884965
D019833	Genistein	ESR2 promotes the reaction [Genistein results in decreased expression of CNN2 protein]	20884965
D019833	Genistein	ESR2 promotes the reaction [Genistein results in decreased expression of COTL1 protein]	20884965
D019833	Genistein	ESR2 promotes the reaction [Genistein results in decreased expression of COX7A2L protein]	20884965
D019833	Genistein	ESR2 promotes the reaction [Genistein results in decreased expression of CSRP1 protein]	20884965
D019833	Genistein	ESR2 promotes the reaction [Genistein results in decreased expression of CYB5A protein]	20884965
D019833	Genistein	ESR2 promotes the reaction [Genistein results in decreased expression of DDRGK1 protein]	20884965
D019833	Genistein	ESR2 promotes the reaction [Genistein results in decreased expression of DMD protein]	20884965
D019833	Genistein	ESR2 promotes the reaction [Genistein results in decreased expression of DNPEP protein]	20884965
D019833	Genistein	ESR2 promotes the reaction [Genistein results in decreased expression of EIF4G1 protein]	20884965
D019833	Genistein	ESR2 promotes the reaction [Genistein results in decreased expression of ESR2 protein]	20884965
D019833	Genistein	ESR2 promotes the reaction [Genistein results in decreased expression of FHL2 protein]	20884965
D019833	Genistein	ESR2 promotes the reaction [Genistein results in decreased expression of FLNA protein]	20884965
D019833	Genistein	ESR2 promotes the reaction [Genistein results in decreased expression of GPS1 protein]	20884965
D019833	Genistein	ESR2 promotes the reaction [Genistein results in decreased expression of H2AFZ protein]	20884965
D019833	Genistein	ESR2 promotes the reaction [Genistein results in decreased expression of HIST1H2AG protein]	20884965
D019833	Genistein	ESR2 promotes the reaction [Genistein results in decreased expression of HIST1H4A protein]	20884965
D019833	Genistein	ESR2 promotes the reaction [Genistein results in decreased expression of HNRNPC protein]	20884965
D019833	Genistein	ESR2 promotes the reaction [Genistein results in decreased expression of ISG15 protein]	20884965
D019833	Genistein	ESR2 promotes the reaction [Genistein results in decreased expression of ISYNA1 protein]	20884965
D019833	Genistein	ESR2 promotes the reaction [Genistein results in decreased expression of ITGAV protein]	20884965
D019833	Genistein	ESR2 promotes the reaction [Genistein results in decreased expression of LDHB protein]	20884965
D019833	Genistein	ESR2 promotes the reaction [Genistein results in decreased expression of LMNA protein]	20884965
D019833	Genistein	ESR2 promotes the reaction [Genistein results in decreased expression of LMNB2 protein]	20884965
D019833	Genistein	ESR2 promotes the reaction [Genistein results in decreased expression of MAP4 protein]	20884965
D019833	Genistein	ESR2 promotes the reaction [Genistein results in decreased expression of MATR3 protein]	20884965
D019833	Genistein	ESR2 promotes the reaction [Genistein results in decreased expression of MX1 protein]	20884965
D019833	Genistein	ESR2 promotes the reaction [Genistein results in decreased expression of NFKB2 protein]	20884965
D019833	Genistein	ESR2 promotes the reaction [Genistein results in decreased expression of PPL protein]	20884965
D019833	Genistein	ESR2 promotes the reaction [Genistein results in decreased expression of PRAF2 protein]	20884965
D019833	Genistein	ESR2 promotes the reaction [Genistein results in decreased expression of PREX1 protein]	20884965
D019833	Genistein	ESR2 promotes the reaction [Genistein results in decreased expression of PRSS8 protein]	20884965
D019833	Genistein	ESR2 promotes the reaction [Genistein results in decreased expression of REEP5 protein]	20884965
D019833	Genistein	ESR2 promotes the reaction [Genistein results in decreased expression of RPL38 protein]	20884965
D019833	Genistein	ESR2 promotes the reaction [Genistein results in decreased expression of S100A16 protein]	20884965
D019833	Genistein	ESR2 promotes the reaction [Genistein results in decreased expression of S100A8 protein]	20884965
D019833	Genistein	ESR2 promotes the reaction [Genistein results in decreased expression of SDHB protein]	20884965
D019833	Genistein	ESR2 promotes the reaction [Genistein results in decreased expression of SLK protein]	20884965
D019833	Genistein	ESR2 promotes the reaction [Genistein results in decreased expression of SRPRA protein]	20884965
D019833	Genistein	ESR2 promotes the reaction [Genistein results in decreased expression of STAT1 protein]	20884965
D019833	Genistein	ESR2 promotes the reaction [Genistein results in decreased expression of TNKS1BP1 protein]	20884965
D019833	Genistein	ESR2 promotes the reaction [Genistein results in decreased expression of TOP2B protein]	20884965
D019833	Genistein	ESR2 promotes the reaction [Genistein results in decreased expression of TTC9C protein]	20884965
D019833	Genistein	ESR2 promotes the reaction [Genistein results in decreased expression of UBE2L6 protein]	20884965
D019833	Genistein	ESR2 promotes the reaction [Genistein results in decreased expression of UBTF protein]	20884965
D019833	Genistein	ESR2 promotes the reaction [Genistein results in decreased expression of UGDH protein]	20884965
D019833	Genistein	ESR2 promotes the reaction [Genistein results in decreased expression of VCL protein]	20884965
D019833	Genistein	ESR2 promotes the reaction [Genistein results in increased expression of ACY1 protein]	20884965
D019833	Genistein	ESR2 promotes the reaction [Genistein results in increased expression of ANKRD36B protein]	20884965
D019833	Genistein	ESR2 promotes the reaction [Genistein results in increased expression of APRT protein]	20884965
D019833	Genistein	ESR2 promotes the reaction [Genistein results in increased expression of ARMC10 protein]	20884965
D019833	Genistein	ESR2 promotes the reaction [Genistein results in increased expression of CANX protein]	20884965
D019833	Genistein	ESR2 promotes the reaction [Genistein results in increased expression of CBX5 protein]	20884965
D019833	Genistein	ESR2 promotes the reaction [Genistein results in increased expression of CD9 protein]	20884965
D019833	Genistein	ESR2 promotes the reaction [Genistein results in increased expression of CLDN1 protein]	20884965
D019833	Genistein	ESR2 promotes the reaction [Genistein results in increased expression of CNPY2 protein]	20884965
D019833	Genistein	ESR2 promotes the reaction [Genistein results in increased expression of COMTD1 protein]	20884965
D019833	Genistein	ESR2 promotes the reaction [Genistein results in increased expression of CRIP1 protein]	20884965
D019833	Genistein	ESR2 promotes the reaction [Genistein results in increased expression of EFHD1 protein]	20884965
D019833	Genistein	ESR2 promotes the reaction [Genistein results in increased expression of ELOVL1 protein]	20884965
D019833	Genistein	ESR2 promotes the reaction [Genistein results in increased expression of EPHX2 protein]	20884965
D019833	Genistein	ESR2 promotes the reaction [Genistein results in increased expression of ESR2 protein]	20884965
D019833	Genistein	ESR2 promotes the reaction [Genistein results in increased expression of FGFR2 protein]	20884965
D019833	Genistein	ESR2 promotes the reaction [Genistein results in increased expression of GIPC1 protein]	20884965
D019833	Genistein	ESR2 promotes the reaction [Genistein results in increased expression of GOT2 protein]	20884965
D019833	Genistein	ESR2 promotes the reaction [Genistein results in increased expression of H1F0 protein]	20884965
D019833	Genistein	ESR2 promotes the reaction [Genistein results in increased expression of HIST1H1B protein]	20884965
D019833	Genistein	ESR2 promotes the reaction [Genistein results in increased expression of HIST1H1C protein]	20884965
D019833	Genistein	ESR2 promotes the reaction [Genistein results in increased expression of HIST1H1E protein]	20884965
D019833	Genistein	ESR2 promotes the reaction [Genistein results in increased expression of HIST1H2AB protein]	20884965
D019833	Genistein	ESR2 promotes the reaction [Genistein results in increased expression of HIST1H2AG protein]	20884965
D019833	Genistein	ESR2 promotes the reaction [Genistein results in increased expression of HIST1H2BN protein]	20884965
D019833	Genistein	ESR2 promotes the reaction [Genistein results in increased expression of HIST1H4A protein]	20884965
D019833	Genistein	ESR2 promotes the reaction [Genistein results in increased expression of HNRNPA2B1 protein]	20884965
D019833	Genistein	ESR2 promotes the reaction [Genistein results in increased expression of HNRNPC protein]	20884965
D019833	Genistein	ESR2 promotes the reaction [Genistein results in increased expression of HNRNPUL2 protein]	20884965
D019833	Genistein	ESR2 promotes the reaction [Genistein results in increased expression of HSD17B8 protein]	20884965
D019833	Genistein	ESR2 promotes the reaction [Genistein results in increased expression of HSPA9 protein]	20884965
D019833	Genistein	ESR2 promotes the reaction [Genistein results in increased expression of ISYNA1 protein]	20884965
D019833	Genistein	ESR2 promotes the reaction [Genistein results in increased expression of KIAA0753 protein]	20884965
D019833	Genistein	ESR2 promotes the reaction [Genistein results in increased expression of KIAA1107 protein]	20884965
D019833	Genistein	ESR2 promotes the reaction [Genistein results in increased expression of KRT18 protein]	20884965
D019833	Genistein	ESR2 promotes the reaction [Genistein results in increased expression of KRT19 protein]	20884965
D019833	Genistein	ESR2 promotes the reaction [Genistein results in increased expression of KRT8 protein]	20884965
D019833	Genistein	ESR2 promotes the reaction [Genistein results in increased expression of LAMP2 protein]	20884965
D019833	Genistein	ESR2 promotes the reaction [Genistein results in increased expression of LMNA protein]	20884965
D019833	Genistein	ESR2 promotes the reaction [Genistein results in increased expression of LYRM7 protein]	20884965
D019833	Genistein	ESR2 promotes the reaction [Genistein results in increased expression of MATR3 protein]	20884965
D019833	Genistein	ESR2 promotes the reaction [Genistein results in increased expression of METTL7A protein]	20884965
D019833	Genistein	ESR2 promotes the reaction [Genistein results in increased expression of MGP protein]	20884965
D019833	Genistein	ESR2 promotes the reaction [Genistein results in increased expression of MRM3 protein]	20884965
D019833	Genistein	ESR2 promotes the reaction [Genistein results in increased expression of MUC1 protein]	20884965
D019833	Genistein	ESR2 promotes the reaction [Genistein results in increased expression of NPM1 protein]	20884965
D019833	Genistein	ESR2 promotes the reaction [Genistein results in increased expression of NUMA1 protein]	20884965
D019833	Genistein	ESR2 promotes the reaction [Genistein results in increased expression of PIP protein]	20884965
D019833	Genistein	ESR2 promotes the reaction [Genistein results in increased expression of PRMT1 protein]	20884965
D019833	Genistein	ESR2 promotes the reaction [Genistein results in increased expression of PTGR2 protein]	20884965
D019833	Genistein	ESR2 promotes the reaction [Genistein results in increased expression of PYGB protein]	20884965
D019833	Genistein	ESR2 promotes the reaction [Genistein results in increased expression of RAB18 protein]	20884965
D019833	Genistein	ESR2 promotes the reaction [Genistein results in increased expression of REEP5 protein]	20884965
D019833	Genistein	ESR2 promotes the reaction [Genistein results in increased expression of RNPEP protein]	20884965
D019833	Genistein	ESR2 promotes the reaction [Genistein results in increased expression of S100A9 protein]	20884965
D019833	Genistein	ESR2 promotes the reaction [Genistein results in increased expression of SEPHS1 protein]	20884965
D019833	Genistein	ESR2 promotes the reaction [Genistein results in increased expression of SLC9A3R1 protein]	20884965
D019833	Genistein	ESR2 promotes the reaction [Genistein results in increased expression of TFRC protein]	20884965
D019833	Genistein	ESR2 promotes the reaction [Genistein results in increased expression of TP53I3 protein]	20884965
D019833	Genistein	ESR2 promotes the reaction [Genistein results in increased expression of TRMT112 protein]	20884965
D019833	Genistein	ESR2 promotes the reaction [Genistein results in increased expression of VPS24 protein]	20884965
D019833	Genistein	ESR2 protein affects the susceptibility to Genistein	17275032
D019833	Genistein	fulvestrant inhibits the reaction [Genistein results in increased expression of ESR2 protein]	24685904
D019833	Genistein	Genistein binds to and results in increased activity of ESR2 protein	11502892\|1186197
D019833	Genistein	Genistein binds to ESR2 protein	10964929\|1136862
D019833	Genistein	[Genistein binds to ESR2 protein] which binds to NCOA2 protein	15123288
D019833	Genistein	[Genistein co-treated with ESR2 protein] results in decreased expression of EGFR mRNA	19347870
D019833	Genistein	[Genistein co-treated with ESR2 protein] results in decreased expression of EGFR protein	19347870
D019833	Genistein	[Genistein co-treated with ESR2 protein] results in increased expression of BGLAP mRNA	19347870
D019833	Genistein	[Genistein co-treated with ESR2 protein] results in increased expression of LTF mRNA	21783566
D019833	Genistein	[Genistein co-treated with ESR2 protein] results in increased expression of PTGS2 mRNA	19347870
D019833	Genistein	[Genistein co-treated with ESR2] results in increased expression of BSP mRNA	19347870
D019833	Genistein	Genistein inhibits the reaction [Estradiol binds to ESR2 protein]	10964929\|1136862
D019833	Genistein	Genistein inhibits the reaction [KAT5 protein results in decreased activity of ESR2 protein]	23857583
D019833	Genistein	Genistein inhibits the reaction [KAT5 protein results in increased activity of ESR2 protein]	23857583
D019833	Genistein	Genistein promotes the reaction [ESR2 protein binds to NCOA1 protein]	10964929
D019833	Genistein	Genistein promotes the reaction [ESR2 protein binds to NCOA2 protein]	10964929
D019833	Genistein	Genistein promotes the reaction [Estradiol results in increased activity of ESR2 protein]	16118406
D019833	Genistein	Genistein results in decreased expression of ESR2 mRNA	15968319
D019833	Genistein	Genistein results in decreased expression of ESR2 protein	20884965
D019833	Genistein	Genistein results in increased activity of ESR2 protein	16118406\|1713222
D019833	Genistein	Genistein results in increased activity of ESR2 protein alternative form	17266178
D019833	Genistein	Genistein results in increased expression of ESR2 mRNA	16033089\|1659623
D019833	Genistein	Genistein results in increased expression of ESR2 mRNA alternative form	16596234
D019833	Genistein	Genistein results in increased expression of ESR2 protein	16033089\|2088496
D019833	Genistein	Methoxychlor metabolite inhibits the reaction [Genistein binds to and results in increased activity of ESR2 protein]	11861976
D019833	Genistein	ESR2 protein affects the reaction [Genistein results in increased expression of SOD2 protein]	23526725
D019833	Genistein	ESR2 protein affects the susceptibility to Genistein	23526725
D019833	Genistein	ESR2 protein alternative form inhibits the reaction [Genistein results in increased expression of ESR2 protein]	27634370
D019833	Genistein	Genistein binds to ESR2 protein	19913605
D019833	Genistein	Genistein results in increased activity of ESR2 protein	19495926
D019833	Genistein	Genistein results in increased expression of ESR2 mRNA	16857750\|1828126
D019833	Genistein	Genistein results in increased expression of ESR2 protein	27634370
D019833	Genistein	NCOA1 protein promotes the reaction [Genistein results in increased expression of ESR2 protein]	27634370
D019833	Genistein	NCOA2 protein promotes the reaction [Genistein results in increased expression of ESR2 protein]	27634370
D019833	Genistein	NCOA2 protein promotes the reaction [Genistein results in increased expression of ESR2 protein alternative form]	27634370
D019833	Genistein	NCOA3 protein promotes the reaction [Genistein results in increased expression of ESR2 protein]	27634370
D019833	Genistein	NCOA3 protein promotes the reaction [Genistein results in increased expression of ESR2 protein alternative form]	27634370
D019833	Genistein	Genistein results in decreased expression of ESR2 mRNA	24992288
D019833	Genistein	[bisphenol A co-treated with Genistein] results in decreased expression of ESR2 protein	24884420
D019833	Genistein	Genistein affects the reaction [Oxygen deficiency affects the expression of ESR2 mRNA]	24333797
D019833	Genistein	Genistein affects the reaction [Oxygen deficiency affects the expression of ESR2 protein]	24333797
D019833	Genistein	Genistein binds to ESR2 protein	11880592\|1991360
D019833	Genistein	[Genistein co-treated with aluminum chloride] results in increased expression of ESR2 mRNA	28552514
D019833	Genistein	[Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in increased expression of ESR2 mRNA	28964809
D019833	Genistein	[Genistein co-treated with Isoflavones] results in increased expression of ESR2 mRNA	20381596
D019833	Genistein	[Genistein co-treated with Methoxychlor] results in increased expression of ESR2 mRNA	16443925
D019833	Genistein	Genistein inhibits the reaction [16 alpha-iodoestradiol binds to ESR2 protein]	9048584
D019833	Genistein	Genistein inhibits the reaction [Estradiol affects the expression of ESR2 mRNA]	17049845
D019833	Genistein	Genistein inhibits the reaction [Estradiol binds to ESR2 protein alternative form]	9492041
D019833	Genistein	Genistein inhibits the reaction [Oxygen deficiency results in decreased expression of ESR2 mRNA]	24333797
D019833	Genistein	Genistein inhibits the reaction [Oxygen deficiency results in decreased expression of ESR2 protein]	24333797
D019833	Genistein	Genistein results in increased expression of ESR2 mRNA	17341692\|2921748
D019833	Genistein	Genistein results in increased expression of ESR2 protein	29217487
D019833	Genistein	Genistein binds to and affects the activity of ESR2 protein	12950458
D019833	Genistein	Genistein results in increased activity of ESR2 protein	11403899
C040641	genistin	[Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in increased expression of ESR2 mRNA	28964809
C007836	geraniol	geraniol binds to ESR2 protein	12495555
C007836	geraniol	geraniol inhibits the reaction [Estradiol binds to ESR2 protein]	12495555
D005947	Glucose	Glucose results in decreased expression of ESR2 mRNA	16621514
D005947	Glucose	Glucose results in increased expression of ESR2 mRNA	16621514
C086566	glycitein	ESR2 affects the reaction [glycitein results in increased expression of CDKN1A]	21161820
C086566	glycitein	ESR2 affects the susceptibility to glycitein	21161820
C086566	glycitein	[Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in increased expression of ESR2 mRNA	28964809
C433283	glycitin	[Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in increased expression of ESR2 mRNA	28964809
C010974	glyphosate	[glyphosate co-treated with Herbicides] results in decreased activity of ESR2 protein	19539684
C010974	glyphosate	glyphosate results in increased expression of ESR2 protein	23756170
C010974	glyphosate	glyphosate results in increased expression of ESR2 protein	27463640
D006064	Gonadotropins, Equine	"ESR2 protein results in increased susceptibility to Gonadotropins, Equine"	15831568
D006064	Gonadotropins, Equine	"[Gonadotropins, Equine co-treated with bisphenol A] results in increased expression of ESR2 protein"	28648634
D055768	Halogenated Diphenyl Ethers	Halogenated Diphenyl Ethers binds to and results in increased activity of ESR2 protein	11335189
D006533	Heptachlor	Heptachlor results in increased activity of ESR2 protein	15064155\|2613924
D006533	Heptachlor	Heptachlor results in increased expression of ESR2 mRNA	19101654
D006534	Heptachlor Epoxide	Heptachlor Epoxide results in increased activity of ESR2 protein	15064155
C481602	heptylparaben	heptylparaben binds to and results in increased activity of ESR2 protein	23567241
D006540	Herbicides	[glyphosate co-treated with Herbicides] results in decreased activity of ESR2 protein	19539684
C517828	hexabrominated diphenyl ether 153	hexabrominated diphenyl ether 153 inhibits the reaction [Estradiol results in increased activity of ESR2 protein]	19672399
C089796	hexabromocyclododecane	hexabromocyclododecane results in decreased expression of ESR2 mRNA	19027819
D006589	Hexestrol	Hexestrol inhibits the reaction [16 alpha-iodoestradiol binds to ESR2 protein]	9048584
C070164	homocastasterone	homocastasterone affects the localization of ESR2 protein	20833159
C070164	homocastasterone	homocastasterone results in decreased expression of ESR2	20833159
C475919	hydroxytamoxifen	ESR2 protein inhibits the reaction [hydroxytamoxifen results in increased expression of FARP1 mRNA]	16849584
C475919	hydroxytamoxifen	ESR2 protein inhibits the reaction [hydroxytamoxifen results in increased expression of IER3 mRNA]	16849584
C475919	hydroxytamoxifen	ESR2 protein inhibits the reaction [hydroxytamoxifen results in increased expression of RAB30 mRNA]	16849584
C475919	hydroxytamoxifen	ESR2 protein inhibits the reaction [hydroxytamoxifen results in increased expression of SOCS1 mRNA]	16849584
C499403	icaritin	"[4-(2-phenyl-5,7-bis(trifluoromethyl)pyrazolo(1,5-a)pyrimidin-3-yl)phenol results in decreased activity of ESR2 protein] inhibits the reaction [icaritin results in increased activity of ESR2 protein]"	22613215
C499403	icaritin	icaritin results in increased activity of ESR2 protein	22613215
C051781	ICI 164384	ICI 164384 binds to ESR2 protein	19913605
D007189	Indans	Indans analog results in decreased activity of ESR2 protein	15737489
D007189	Indans	Indans analog results in increased activity of ESR2 protein	15737489
C047437	indenestrol	indenestrol binds to and results in increased activity of ESR2 protein	15465114
D019469	Indinavir	[Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in decreased expression of ESR2 mRNA	16931933
D007211	Indoles	Indoles analog binds to and affects the activity of ESR2 protein	15911274
C018986	ipriflavone	ipriflavone binds to and results in increased activity of ESR2 protein	9751507
C530234	irilone	irilone results in increased expression of ESR2 mRNA	23982890
C045922	isobutyl-4-hydroxybenzoate	isobutyl-4-hydroxybenzoate binds to ESR2 protein	11193391
D015056	1-Methyl-3-isobutylxanthine	fulvestrant inhibits the reaction [[[INS protein co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone] co-treated with bisphenol A] results in increased activity of ESR2 protein]	26944108
D015056	1-Methyl-3-isobutylxanthine	[[INS protein co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone] co-treated with bisphenol A] results in increased activity of ESR2 protein	26944108
D015056	1-Methyl-3-isobutylxanthine	[[INS protein co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone] co-treated with Diethylstilbestrol] results in decreased activity of ESR2 protein	26944108
C471067	isobutylparaben	isobutylparaben binds to and results in increased activity of ESR2 protein	23567241
C471067	isobutylparaben	isobutylparaben binds to ESR2 protein	20132880
D007529	Isoflavones	ESR2 gene SNP affects the susceptibility to Isoflavones	16522905
D007529	Isoflavones	[Genistein co-treated with Isoflavones] results in increased expression of ESR2 mRNA	20381596
D007529	Isoflavones	Isoflavones affects the expression of ESR2	21112483
D007529	Isoflavones	Isoflavones results in decreased expression of ESR2 protein	22155228
C038267	isopropyl 4,4'-dibromobenzilate	"isopropyl 4,4'-dibromobenzilate results in increased activity of ESR2 protein"	15064155
C098802	isopropyl 4-hydroxybenzoate	isopropyl 4-hydroxybenzoate binds to ESR2 protein	11193391
C113642	JK 1624F2-1	JK 1624F2-1 results in decreased expression of ESR2 mRNA	16406510
C006552	kaempferol	Estradiol affects the reaction [kaempferol results in increased activity of ESR2 protein]	16118406
C006552	kaempferol	kaempferol binds to and results in increased activity of ESR2 protein	15182386\|9751507
C006552	kaempferol	kaempferol binds to ESR2 protein	12224631\|1470656
C006552	kaempferol	kaempferol inhibits the reaction [Estradiol binds to ESR2 protein]	9751507
C006552	kaempferol	kaempferol results in increased activity of ESR2 protein	16118406\|1893707
C006552	kaempferol	ESR2 protein alternative form inhibits the reaction [kaempferol results in increased expression of ESR2 protein]	27634370
C006552	kaempferol	kaempferol binds to ESR2 protein	19913605
C006552	kaempferol	kaempferol results in increased expression of ESR2 protein	27634370
C006552	kaempferol	kaempferol binds to ESR2 protein	19913605
D007783	Lactones	Lactones results in increased expression of ESR2 protein	14702340
C111332	Lasofoxifene	Lasofoxifene results in increased expression of ESR2 protein	16837883
C089549	lauric acid methyl ester	lauric acid methyl ester binds to and results in decreased activity of ESR2 protein	27633901
C089549	lauric acid methyl ester	lauric acid methyl ester binds to and results in increased activity of ESR2 protein	27633901
D010773	Leptophos	Leptophos results in increased activity of ESR2 protein	15064155
C067431	letrozole	[Ethinyl Estradiol co-treated with letrozole] results in increased expression of ESR2 mRNA	21963593
D001556	Lindane	Lindane results in increased activity of ESR2 protein	15064155\|2613924
D008043	Linseed Oil	Linseed Oil inhibits the reaction [Tamoxifen results in decreased expression of ESR2 mRNA]	21138602
C083152	liquiritigenin	liquiritigenin results in increased activity of ESR2 protein	25106122
D047311	Luteolin	Luteolin binds to ESR2 protein	12224631
D047311	Luteolin	Luteolin results in increased activity of ESR2 protein	16860978
C504960	LY2066948	LY2066948 binds to ESR2 protein	16002528
C115121	LY 353381	LY 353381 analog results in decreased activity of ESR2 protein	17654759
C115121	LY 353381	LY 353381 binds to ESR2 protein	11731420\|1678035
C115121	LY 353381	LY 353381 results in decreased activity of ESR2 protein	17654759
C015329	lycopene	lycopene inhibits the reaction [Estradiol results in increased activity of ESR2 protein]	17051425
D008550	Melatonin	Ethanol inhibits the reaction [Melatonin results in decreased expression of ESR2 protein]	23591044
D008550	Melatonin	[Melatonin co-treated with Ethanol] results in increased expression of ESR2 protein	23591044
D008550	Melatonin	Melatonin inhibits the reaction [Ethanol results in decreased expression of ESR2 protein]	23591044
D008550	Melatonin	Melatonin results in decreased expression of ESR2 protein	23591044
D008628	Mercury	Mercury results in increased expression of ESR2 mRNA	16823088
D008687	Metformin	Metformin inhibits the reaction [Testosterone results in decreased expression of ESR2 mRNA]	26492952
D008713	Methimazole	Methimazole results in decreased expression of ESR2 mRNA	17408746
D008714	Methiocarb	Methiocarb results in increased activity of ESR2 protein	15064155
D008714	Methiocarb	Methiocarb results in increased expression of ESR2 mRNA	15130599
C013598	methoxyacetic acid	afimoxifene inhibits the reaction [methoxyacetic acid promotes the reaction [Estradiol results in increased activity of ESR2 protein]]	15103026
C013598	methoxyacetic acid	fulvestrant inhibits the reaction [methoxyacetic acid promotes the reaction [Estradiol results in increased activity of ESR2 protein]]	15103026
C013598	methoxyacetic acid	methoxyacetic acid promotes the reaction [Estradiol results in increased activity of ESR2 protein]	15103026\|1848617
C013598	methoxyacetic acid	methoxyacetic acid results in increased expression of and results in increased activity of ESR2 protein	14662790
C013598	methoxyacetic acid	methoxyacetic acid results in increased expression of ESR2 mRNA	14662790
D008731	Methoxychlor	[Methoxychlor affects the activity of ESR2 protein] promotes the reaction [LIF protein results in increased activity of STAT3 protein]	14975756
D008731	Methoxychlor	Methoxychlor analog binds to and results in decreased activity of ESR2 protein	10999957
D008731	Methoxychlor	Methoxychlor binds to and results in decreased activity of ESR2 protein	16626760
D008731	Methoxychlor	Methoxychlor binds to ESR2 protein	12224631\|9751507
D008731	Methoxychlor	Methoxychlor inhibits the reaction [Estradiol binds to ESR2 protein]	9751507
D008731	Methoxychlor	Methoxychlor metabolite binds to and results in decreased activity of ESR2 protein	10579340\|1186197
D008731	Methoxychlor	Methoxychlor metabolite inhibits the reaction [Genistein binds to and results in increased activity of ESR2 protein]	11861976
D008731	Methoxychlor	Methoxychlor results in increased activity of ESR2 protein	26139245
D008731	Methoxychlor	Methoxychlor affects the activity of ESR2 protein	15451043
D008731	Methoxychlor	Methoxychlor results in increased expression of ESR2 mRNA	18279978
D008731	Methoxychlor	ESR1 protein inhibits the reaction [Methoxychlor results in increased expression of ESR2 mRNA]	21252393
D008731	Methoxychlor	[Estradiol co-treated with Methoxychlor metabolite] results in decreased expression of ESR2 mRNA	11509743
D008731	Methoxychlor	[Estradiol co-treated with Methoxychlor metabolite] results in increased expression of ESR2 mRNA	11509743
D008731	Methoxychlor	Methoxychlor metabolite results in decreased expression of ESR2 mRNA	11509743
D008731	Methoxychlor	Methoxychlor metabolite results in increased expression of ESR2 mRNA	11509743
D008731	Methoxychlor	Methoxychlor results in increased expression of ESR2 mRNA	21252393
D008731	Methoxychlor	[Genistein co-treated with Methoxychlor] results in increased expression of ESR2 mRNA	16443925
D008731	Methoxychlor	Methoxychlor inhibits the reaction [Estradiol binds to ESR2 protein alternative form]	9492041
D008731	Methoxychlor	Methoxychlor inhibits the reaction [FSHB protein results in increased expression of ESR2 mRNA]	25549949
D008731	Methoxychlor	Methoxychlor inhibits the reaction [FSHB protein results in increased expression of ESR2 protein]	25549949
D008731	Methoxychlor	Methoxychlor metabolite binds to and results in decreased activity of ESR2 protein	10579340
D008731	Methoxychlor	Methoxychlor results in decreased expression of ESR2 mRNA	22285353
D008731	Methoxychlor	Methoxychlor results in decreased expression of ESR2 protein	18848953
D008731	Methoxychlor	Methoxychlor results in increased methylation of ESR2 promoter	19589859
D008731	Methoxychlor	"[o,p'-DDT co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Methoxychlor co-treated with Endosulfan co-treated with DDT] results in increased activity of ESR2 protein"	9860891
D008731	Methoxychlor	Methoxychlor metabolite binds to and results in decreased activity of ESR2 protein	11509743
D008731	Methoxychlor	Methoxychlor results in decreased expression of ESR2	23303685
D008731	Methoxychlor	Methoxychlor results in increased methylation of ESR2 promoter	23303685
D008767	Methylmercury Compounds	Methylmercury Compounds binds to ESR2 protein	15712295
D008769	Methylnitronitrosoguanidine	Methylnitronitrosoguanidine results in increased expression of ESR2 mRNA	22330348
D008769	Methylnitronitrosoguanidine	Methylnitronitrosoguanidine results in increased expression of ESR2 protein	21628965\|2233034
C019012	methyl palmitate	methyl palmitate binds to and results in decreased activity of ESR2 protein	27633901
C015358	methylparaben	methylparaben results in increased expression of ESR2 mRNA	25128701
C015358	methylparaben	methylparaben results in increased expression of ESR2 protein	25128701
C008493	methylselenic acid	methylselenic acid affects the expression of ESR2 mRNA	16928829
C008493	methylselenic acid	methylselenic acid results in increased expression of ESR2 mRNA	15833885
D008797	Metyrapone	Metyrapone results in increased expression of ESR2 mRNA	16713641
C517398	MF101 extract	MF101 extract binds to and affects the folding of and results in increased activity of ESR2 protein	17095596
C517398	MF101 extract	MF101 extract promotes the reaction [ESR2 protein binds to KRT19 promoter]	17095596
D015735	Mifepristone	Mifepristone binds to and results in decreased activity of ESR2 protein	25752796
D015735	Mifepristone	Mifepristone affects the expression of ESR2 mRNA	20686183
C103325	mono-benzyl phthalate	mono-benzyl phthalate promotes the reaction [Estradiol results in increased activity of ESR2 protein]	28571686
C011310	moxestrol	moxestrol inhibits the reaction [16 alpha-iodoestradiol binds to ESR2 protein]	9048584
D009173	Mycophenolic Acid	Mycophenolic Acid binds to and results in decreased activity of ESR2 protein	25752796
C451426	N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide	"[fludioxonil co-treated with N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide co-treated with propamocarb] results in increased activity of ESR2 protein"	26812056
C451426	N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide	"[fludioxonil co-treated with N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide] results in increased activity of ESR2 protein"	26812056
C451426	N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide	"N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide inhibits the reaction [Estradiol results in increased expression of ESR2 mRNA]"	23436777
C451426	N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide	"N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide results in increased activity of ESR2 protein"	26812056
C451426	N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide	"N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide results in increased expression of ESR2 mRNA"	23436777
D009256	Nafoxidine	Nafoxidine inhibits the reaction [16 alpha-iodoestradiol binds to ESR2 protein]	9048584
D037742	Nanotubes, Carbon	"Nanotubes, Carbon analog results in decreased expression of ESR2 mRNA"	25554681
D037742	Nanotubes, Carbon	"Nanotubes, Carbon results in decreased expression of ESR2 mRNA"	25554681
C005273	naringenin	naringenin binds to and results in increased activity of ESR2 protein	9751507
C005273	naringenin	naringenin binds to ESR2 protein	12224631\|1656667
C005273	naringenin	naringenin inhibits the reaction [Estradiol binds to ESR2 protein]	16566672\|9751507
C005273	naringenin	naringenin results in increased activity of ESR2 protein	16118406\|1771681
C005273	naringenin	naringenin binds to ESR2 protein	19913605
C005273	naringenin	naringenin binds to ESR2 protein	19913605
C005274	naringin	fulvestrant inhibits the reaction [naringin results in increased expression of ESR2 mRNA]	23596885
C005274	naringin	naringin results in increased expression of ESR2 mRNA	23596885
C053761	n-butylbenzene	n-butylbenzene binds to ESR2 protein	12224631
C065565	N-butylbenzenesulfonamide	N-butylbenzenesulfonamide binds to and results in decreased activity of ESR2 protein	27633901
D000068577	Nebivolol	Nebivolol affects the activity of ESR2 protein	19330906
D000068577	Nebivolol	Nebivolol binds to and results in decreased activity of ESR2 protein	25752796
D009532	Nickel	Nickel results in increased expression of ESR2 mRNA	24084258
C001870	nonachlor	nonachlor results in increased expression of ESR2 mRNA	26372180
C001870	nonachlor	nonachlor binds to and results in increased activity of ESR2 protein	16626760
C025256	nonylphenol	nonylphenol binds to and results in increased activity of ESR2 protein	14709801\|9751507
C025256	nonylphenol	nonylphenol binds to ESR2 protein	14723943
C025256	nonylphenol	nonylphenol results in increased activity of ESR2 protein	14754635\|1675637
C025256	nonylphenol	Sodium Hypochlorite inhibits the reaction [nonylphenol binds to ESR2 protein]	14723943
C025256	nonylphenol	"3,4,3',4'-tetrachlorobiphenyl inhibits the reaction [nonylphenol results in increased expression of ESR2 mRNA]"	16291559
C025256	nonylphenol	nonylphenol results in increased expression of ESR2 mRNA	16291559
D009640	Norethindrone	Norethindrone binds to and results in increased activity of ESR2 protein	25752796
D009640	Norethindrone	Norethindrone results in increased activity of ESR2 protein	10836199
C024262	norethindrone acetate	norethindrone acetate binds to and results in increased activity of ESR2 protein	25752796
D009641	Norethynodrel	Norethynodrel results in increased activity of ESR2 protein	10836199
D009644	Norgestrel	Norgestrel results in increased activity of ESR2 protein	10836199
D016912	Levonorgestrel	Levonorgestrel results in increased activity of ESR2 protein	10836199
C072936	notoginsenoside R1	notoginsenoside R1 results in increased expression of ESR2	24720662
C088673	octocrylene	octocrylene binds to and results in increased activity of ESR2 protein	16079615
C118580	octylmethoxycinnamate	octylmethoxycinnamate binds to and results in increased activity of ESR2 protein	27633901
C474055	octylphenol	octylphenol inhibits the reaction [Streptozocin results in decreased expression of ESR2 mRNA]	24781736
C474055	octylphenol	octylphenol results in increased expression of ESR2 mRNA	24781736
C474055	octylphenol	octylphenol results in increased expression of ESR2 mRNA	11108262
C050052	O-desmethylangolensin	Estradiol affects the reaction [O-desmethylangolensin affects the activity of ESR2 protein]	16965913
C507134	ON 01910	ON 01910 results in increased expression of ESR2 mRNA	22351695
C016340	o,p'-DDT	"o,p'-DDT results in increased expression of ESR2 mRNA"	26372180
C016340	o,p'-DDT	"o,p'-DDT binds to and results in increased activity of ESR2 protein"	16626760\|9751507
C016340	o,p'-DDT	"o,p'-DDT results in decreased expression of ESR2 mRNA"	18700809
C016340	o,p'-DDT	"o,p'-DDT results in increased activity of ESR2 protein"	15064155\|2681205
C016340	o,p'-DDT	"o,p'-DDT results in decreased expression of ESR2 mRNA"	28263910
C016340	o,p'-DDT	"o,p'-DDT results in decreased expression of ESR2 protein"	28263910
C016340	o,p'-DDT	"o,p'-DDT results in increased expression of ESR2 mRNA"	20686349\|2114596
C016340	o,p'-DDT	"[o,p'-DDT co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Methoxychlor co-treated with Endosulfan co-treated with DDT] results in increased activity of ESR2 protein"	9860891
C016340	o,p'-DDT	"o,p'-DDT results in increased activity of ESR2 protein"	9860891
C016340	o,p'-DDT	"o,p'-DDT results in decreased expression of ESR2 protein"	18195494
C508548	ormeloxifene	ormeloxifene inhibits the reaction [ESR2 protein binds to NCOA1 protein]	19460436
D008939	Mitotane	Mitotane results in increased expression of ESR2 mRNA	26372180
D008939	Mitotane	Mitotane results in increased activity of ESR2 protein	26139245
C485800	osajin	osajin results in decreased expression of ESR2 mRNA	20706672
D010091	Oximes	Oximes analog binds to and results in decreased activity of ESR2 protein	12628652
C005290	oxybenzone	oxybenzone binds to and results in increased activity of ESR2 protein	16079615
D010100	Oxygen	Estradiol affects the reaction [Oxygen deficiency affects the expression of ESR2 mRNA]	24333797
D010100	Oxygen	Estradiol affects the reaction [Oxygen deficiency affects the expression of ESR2 protein]	24333797
D010100	Oxygen	Estradiol inhibits the reaction [Oxygen deficiency results in decreased expression of ESR2 mRNA]	24333797
D010100	Oxygen	Estradiol inhibits the reaction [Oxygen deficiency results in decreased expression of ESR2 protein]	24333797
D010100	Oxygen	Genistein affects the reaction [Oxygen deficiency affects the expression of ESR2 mRNA]	24333797
D010100	Oxygen	Genistein affects the reaction [Oxygen deficiency affects the expression of ESR2 protein]	24333797
D010100	Oxygen	Genistein inhibits the reaction [Oxygen deficiency results in decreased expression of ESR2 mRNA]	24333797
D010100	Oxygen	Genistein inhibits the reaction [Oxygen deficiency results in decreased expression of ESR2 protein]	24333797
D010100	Oxygen	Oxygen deficiency affects the expression of ESR2 mRNA	18457817\|2433379
D010100	Oxygen	Oxygen deficiency affects the expression of ESR2 protein	24333797
D010100	Oxygen	Oxygen deficiency results in decreased expression of ESR2 mRNA	24333797
D010100	Oxygen	Oxygen deficiency results in decreased expression of ESR2 protein	24333797
D010100	Oxygen	parthenocissin A analog affects the reaction [Oxygen deficiency affects the expression of ESR2 mRNA]	24333797
D010100	Oxygen	parthenocissin A analog affects the reaction [Oxygen deficiency affects the expression of ESR2 protein]	24333797
D010100	Oxygen	parthenocissin A analog inhibits the reaction [Oxygen deficiency results in decreased expression of ESR2 mRNA]	24333797
D010100	Oxygen	parthenocissin A analog inhibits the reaction [Oxygen deficiency results in decreased expression of ESR2 protein]	24333797
D010100	Oxygen	resveratrol affects the reaction [Oxygen deficiency affects the expression of ESR2 mRNA]	24333797
D010100	Oxygen	resveratrol affects the reaction [Oxygen deficiency affects the expression of ESR2 protein]	24333797
D010100	Oxygen	resveratrol inhibits the reaction [Oxygen deficiency results in decreased expression of ESR2 mRNA]	24333797
D010100	Oxygen	resveratrol inhibits the reaction [Oxygen deficiency results in decreased expression of ESR2 protein]	24333797
D017239	Paclitaxel	alitretinoin inhibits the reaction [Paclitaxel results in increased expression of ESR2 mRNA]	19340624
D017239	Paclitaxel	Paclitaxel results in decreased expression of ESR2 mRNA	23956100
D017239	Paclitaxel	Paclitaxel results in increased expression of ESR2 mRNA	19340624
C549189	parthenocissin A	parthenocissin A analog affects the reaction [Oxygen deficiency affects the expression of ESR2 mRNA]	24333797
C549189	parthenocissin A	parthenocissin A analog affects the reaction [Oxygen deficiency affects the expression of ESR2 protein]	24333797
C549189	parthenocissin A	parthenocissin A analog inhibits the reaction [Oxygen deficiency results in decreased expression of ESR2 mRNA]	24333797
C549189	parthenocissin A	parthenocissin A analog inhibits the reaction [Oxygen deficiency results in decreased expression of ESR2 protein]	24333797
C030856	pendimethalin	pendimethalin results in increased activity of ESR2 protein	15064155
C030856	pendimethalin	pendimethalin results in increased expression of ESR2 mRNA	19897005
C517827	pentabrominated diphenyl ether 100	pentabrominated diphenyl ether 100 inhibits the reaction [Estradiol results in increased activity of ESR2 protein]	19672399
C086401	pentabromodiphenyl ether	pentabromodiphenyl ether promotes the reaction [Estradiol results in decreased expression of ESR2 mRNA]	16414171
C086401	pentabromodiphenyl ether	pentabromodiphenyl ether results in increased expression of ESR2 mRNA	16414171
C036567	perfluorodecanoic acid	perfluorodecanoic acid results in increased expression of ESR2 mRNA	21984479
C522391	perfluorododecanoic acid	perfluorododecanoic acid results in decreased expression of ESR2 mRNA	19429406
C101816	perfluoro-n-nonanoic acid	perfluoro-n-nonanoic acid results in increased expression of ESR2 mRNA	21984479
C076994	perfluorooctane sulfonic acid	perfluorooctane sulfonic acid results in increased expression of ESR2 mRNA	21984479
C023036	perfluorooctanoic acid	perfluorooctanoic acid results in increased expression of ESR2 mRNA	18709148\|2198447
D010575	Pesticides	Pesticides results in increased expression of ESR2 mRNA	20574910
C033117	phantolid	phantolid binds to and results in decreased activity of ESR2 protein	15537743
C031181	phenanthrene	phenanthrene analog binds to ESR2 protein	12672240
C006166	phenothrin	phenothrin results in decreased expression of ESR2 protein	15118252
D004849	Phenylphosphonothioic Acid, 2-Ethyl 2-(4-Nitrophenyl) Ester	"Phenylphosphonothioic Acid, 2-Ethyl 2-(4-Nitrophenyl) Ester results in increased activity of ESR2 protein"	15064155
D010693	Phloretin	Phloretin binds to and results in increased activity of ESR2 protein	9751507
D010693	Phloretin	Phloretin binds to ESR2 protein	12224631
C032279	phthalic acid	phthalic acid metabolite binds to and results in decreased activity of ESR2 protein	15840436
C032279	phthalic acid	phthalic acid results in increased degradation of ESR2 protein	14702340
C032279	phthalic acid	phthalic acid promotes the reaction [PSMC5 protein binds to ESR2 protein]	14702340
D010795	Phthalic Acids	Phthalic Acids results in decreased expression of ESR2 mRNA	21061450
D048789	Phytoestrogens	ESR2 promoter SNP affects the susceptibility to Phytoestrogens	16921512
D048789	Phytoestrogens	Phytoestrogens analog binds to ESR2 protein	15887952
D048789	Phytoestrogens	Phytoestrogens binds to and results in increased activity of ESR2 protein	16076101
D048789	Phytoestrogens	Phytoestrogens binds to ESR2 protein	16566672
D048789	Phytoestrogens	Phytoestrogens inhibits the reaction [Estradiol binds to ESR2 protein]	16566672
D048789	Phytoestrogens	Phytoestrogens results in increased expression of ESR2 mRNA	16033089
D048789	Phytoestrogens	Phytoestrogens results in increased expression of ESR2 protein	16033089
C003140	phytofluene	[(all-E) phytoene co-treated with phytofluene] inhibits the reaction [Estradiol results in increased activity of ESR2 protein]	17051425
D010936	Plant Extracts	Plant Extracts binds to and results in increased activity of ESR2 protein	16076101
D010936	Plant Extracts	Plant Extracts binds to ESR2 protein	11368622\|1470656
D010936	Plant Extracts	Plant Extracts inhibits the reaction [Estradiol binds to ESR2 protein]	11368622
D010936	Plant Extracts	Plant Extracts inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ESR2 mRNA]	20559769
D010936	Plant Extracts	Plant Extracts promotes the reaction [Tamoxifen inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ESR2 mRNA]]	20559769
D010936	Plant Extracts	[Plant Extracts co-treated with aluminum chloride] results in increased expression of ESR2 mRNA	28552514
D028321	Plant Preparations	fulvestrant inhibits the reaction [Plant Preparations results in increased activity of ESR2 protein]	17935960
D028321	Plant Preparations	Plant Preparations results in increased activity of ESR2 protein	17935960
D028321	Plant Preparations	Plant Preparations results in decreased expression of ESR2 protein	17398067
D011075	Polybrominated Biphenyls	Polybrominated Biphenyls metabolite inhibits the reaction [Estradiol results in increased activity of ESR2 protein]	19672399
D011075	Polybrominated Biphenyls	Polybrominated Biphenyls metabolite results in increased activity of ESR2 protein	19672399
D011078	Polychlorinated Biphenyls	Polychlorinated Biphenyls metabolite inhibits the reaction [Estradiol results in increased expression of ESR2 mRNA]	12377985
C058229	polydatin	ESR2 gene mutant form inhibits the reaction [polydatin results in increased expression of SOD2 protein]	24361291
C474837	pomiferin	pomiferin results in decreased expression of ESR2 mRNA	20706672
C045362	prochloraz	fulvestrant inhibits the reaction [prochloraz results in decreased expression of ESR2 mRNA]	15130599
C045362	prochloraz	prochloraz promotes the reaction [Estradiol results in increased expression of ESR2 mRNA]	15261991
C045362	prochloraz	prochloraz results in decreased expression of ESR2 mRNA	15130599
C045362	prochloraz	prochloraz results in decreased expression of ESR2 mRNA	24992288
D011374	Progesterone	Progesterone results in increased expression of ESR2 mRNA	23012394
D011374	Progesterone	Progesterone binds to ESR2 protein	19913605
D011374	Progesterone	Progesterone metabolite results in increased expression of ESR2 mRNA	17683929
D011374	Progesterone	ESR2 affects the reaction [[Estradiol co-treated with Progesterone] results in increased expression of OXT mRNA]	12834440
D011374	Progesterone	Progesterone inhibits the reaction [ESR2 protein promotes the reaction [Estradiol results in increased expression of LPL mRNA]]	17974624
D011374	Progesterone	[Estradiol co-treated with Progesterone] results in decreased expression of ESR2 mRNA	21277368
D011374	Progesterone	Progesterone inhibits the reaction [Estradiol results in increased expression of ESR2 mRNA]	19094096
D011374	Progesterone	Progesterone results in decreased expression of ESR2 mRNA	19094096
D011374	Progesterone	Progesterone binds to ESR2 protein	19913605
C033205	propamocarb	"[fludioxonil co-treated with N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide co-treated with propamocarb] results in increased activity of ESR2 protein"	26812056
C033205	propamocarb	propamocarb results in increased activity of ESR2 protein	26812056
D011429	Propolis	Propolis binds to ESR2 protein	25786527
D011429	Propolis	Propolis inhibits the reaction [Estradiol binds to ESR2 protein]	25786527
D011429	Propolis	Propolis results in decreased expression of ESR2 mRNA	20706672
D011435	Propyl Gallate	Propyl Gallate results in increased activity of ESR2 protein	16756374
C006068	propylparaben	propylparaben binds to and results in increased activity of ESR2 protein	23567241
C006068	propylparaben	propylparaben binds to ESR2 protein	11193391
C006068	propylparaben	propylparaben results in increased expression of ESR2 mRNA	25128701
C006068	propylparaben	propylparaben results in increased expression of ESR2 protein	25128701
C006068	propylparaben	propylparaben binds to ESR2 protein	20132880
C032072	prothiophos	prothiophos results in increased activity of ESR2 protein	15064155
C107773	pterostilbene	ESR2 gene mutant form inhibits the reaction [pterostilbene results in increased expression of SOD2 protein]	24361291
C019566	p-tert-amylphenol	p-tert-amylphenol binds to ESR2 protein	19913605
C033607	puerarin	puerarin results in decreased activity of ESR2 protein	18937077
C033607	puerarin	puerarin results in decreased expression of ESR2 mRNA	20706672
C033607	puerarin	puerarin results in decreased expression of ESR2 mRNA	22919047
C033607	puerarin	puerarin binds to ESR2 protein	25828059
C031280	pyrazole	pyrazole analog binds to ESR2 protein	17909483
D011720	Pyrazoles	Pyrazoles analog binds to and results in decreased activity of ESR2 protein	19772920
C587274	Qing Ye Dan	Qing Ye Dan inhibits the reaction [Testosterone results in decreased expression of ESR2 protein]	27866977
D011794	Quercetin	ESR2 protein results in increased susceptibility to Quercetin	21732360
D011794	Quercetin	[ESR2 protein results in increased susceptibility to Quercetin] which results in increased cleavage of CASP3 protein	21732360
D011794	Quercetin	[ESR2 protein results in increased susceptibility to Quercetin] which results in increased cleavage of PARP1 protein	21732360
D011794	Quercetin	[ESR2 protein results in increased susceptibility to Quercetin] which results in increased expression of PTEN protein	21732360
D011794	Quercetin	Estradiol affects the reaction [Quercetin results in increased activity of ESR2 protein]	16118406
D011794	Quercetin	Quercetin binds to and results in increased activity of ESR2 protein	11502892\|1518238
D011794	Quercetin	Quercetin binds to ESR2 protein	12224631\|1470656
D011794	Quercetin	Quercetin promotes the reaction [Estradiol results in increased activity of ESR2 protein]	22613215
D011794	Quercetin	Quercetin results in increased activity of ESR2 protein	16118406\|1895514
D011794	Quercetin	Quercetin results in increased expression of ESR2 mRNA	15182386
D011794	Quercetin	Quercetin results in increased expression of ESR2 protein	24299158
D011794	Quercetin	SB 203580 inhibits the reaction [[ESR2 protein results in increased susceptibility to Quercetin] which results in increased cleavage of CASP3 protein]	21732360
D011794	Quercetin	SB 203580 inhibits the reaction [[ESR2 protein results in increased susceptibility to Quercetin] which results in increased cleavage of PARP1 protein]	21732360
C009145	quinalphos	quinalphos results in increased activity of ESR2 protein	15064155
D020849	Raloxifene Hydrochloride	ESR2 protein affects the reaction [Raloxifene Hydrochloride results in decreased expression of EDN3 mRNA]	14699072
D020849	Raloxifene Hydrochloride	ESR2 protein affects the reaction [Raloxifene Hydrochloride results in decreased expression of FLNB mRNA]	14699072
D020849	Raloxifene Hydrochloride	ESR2 protein affects the reaction [Raloxifene Hydrochloride results in decreased expression of IER3 mRNA]	14699072
D020849	Raloxifene Hydrochloride	ESR2 protein affects the reaction [Raloxifene Hydrochloride results in decreased expression of KLRC2 mRNA]	14699072
D020849	Raloxifene Hydrochloride	ESR2 protein affects the reaction [Raloxifene Hydrochloride results in decreased expression of MSMB mRNA]	14699072
D020849	Raloxifene Hydrochloride	ESR2 protein affects the reaction [Raloxifene Hydrochloride results in decreased expression of NCF2 mRNA]	14699072
D020849	Raloxifene Hydrochloride	ESR2 protein affects the reaction [Raloxifene Hydrochloride results in increased expression of GABRR1 mRNA]	14699072
D020849	Raloxifene Hydrochloride	ESR2 protein affects the reaction [Raloxifene Hydrochloride results in increased expression of METTL7A mRNA]	14699072
D020849	Raloxifene Hydrochloride	ESR2 protein promotes the reaction [Raloxifene Hydrochloride results in increased activity of TERT protein]	16798746
D020849	Raloxifene Hydrochloride	ESR2 protein results in increased susceptibility to Raloxifene Hydrochloride	17638070
D020849	Raloxifene Hydrochloride	Raloxifene Hydrochloride binds to and results in increased activity of ESR2 protein	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of ABCC1 mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of ACKR3 mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of ACSL1 mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of AGO2 mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of AKAP1 mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of ARL4C mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of ASB13 mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of C14ORF132 mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of C2CD2 mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of CA12 mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of CALM1 mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of CASKIN2 mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of CASP7 mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of CCND1 mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of CDK5R1 mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of CEBPB mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of CERS6 mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of CLCN4 mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of CRISPLD2 mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of CSDC2 mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of CUEDC1 mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of CYP19A1 mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of CYP24A1 mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of CYP26B1 mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of DOCK9 mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of EDNRA mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of ELF3 mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of ENDOD1 mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of EVI2A mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of FADD mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of FGD6 mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of FGFR2 mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of FHL2 mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of FLNB mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of FOSL2 mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of FOXO1 mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of FST mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of GPRC5C mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of HEG1 mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of HK1 mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of HMOX1 mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of HPCAL1 mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of HSPB8 mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of HTR3A mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of INPP5A mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of IVL mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of KAZN mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of KCTD12 mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of KIF3C mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of KLRC3 mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of KLRK1 mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of LBH mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of LMNB2 mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of LRIG1 mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of LRRC20 mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of LYSMD4 mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of MAFF mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of MAGEA8 mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of MAP3K5 mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of MAP3K8 mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of MAPKAPK2 mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of MBNL2 mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of MDFIC mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of MEF2A mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of MMP12 mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of MN1 mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of MPPED2 mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of MYT1L mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of NAV2 mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of NCF2 mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of NCOA1 mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of NCOA4 mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of NDRG4 mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of NFATC1 mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of NFIL3 mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of NFKBIA mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of NINJ1 mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of NPR2 mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of NR1D1 mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of NR2F6 mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of NUAK1 mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of OSBPL3 mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of OTUB2 mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of PCTP mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of PDLIM3 mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of PHC2 mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of PHF11 mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of PITPNC1 mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of PRKCZ mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of PTGER3 mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of PTGES mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of RCOR3 mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of RET mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of RETREG1 mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of RFTN1 mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of RGL1 mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of RHOF mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of RPS6KA2 mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of SALL1 mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of SCNN1A mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of SEMA3F mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of SERPINB6 mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of SLC18A3 mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of SREBF1 mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of SSH1 mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of ST3GAL1 mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of STK24 mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of SYBU mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of SYNJ2 mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of SYNPO mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of TACC1 mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of TACC2 mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of TBXA2R mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of TGFA mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of TMOD1 mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of TNS3 mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of TOB1 mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of TRAF3IP2 mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of UPF1 mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of WNT5A mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of ZCCHC24 mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of ZMIZ1 mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of ZNF395 mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of ADAM19 mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of ADORA2B mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of AMIGO2 mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of ANKRD1 mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of AREG mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of ATF3 mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of BIRC3 mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of CCL20 mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of CCL2 mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of CDH2 mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of CDO1 mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of CXCL12 mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of CXCL8 mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of DACT1 mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of DCBLD2 mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of DUSP2 mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of DUSP5 mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of EGR1 mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of ENC1 mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of FUT9 mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of GAD1 mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of GRB10 mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of GYG1 mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of HBEGF mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of ID4 mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of IFNGR2 mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of INHBA mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of JAG1 mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of KRT17 mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of KRT34 mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of LDLRAD4 mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of LMCD1 mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of MAP2K3 mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of NAB1 mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of NFKBIE mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of NR3C1 mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of NR4A3 mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of OCLN mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of PCDH7 mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of PDP1 mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of PTGS2 mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of PTP4A3 mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of PTX3 mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of RASGRP1 mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of RCAN2 mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of RFK mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of RGS4 mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of RRAD mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of SERPINE1 mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of SLCO4C1 mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of SOD2 mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of TCIM mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of TGFB2 mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of TGFBI mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of TMEM158 mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of TNC mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of TNFRSF11B mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of TNFRSF21 mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of TNIK mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of TRAF5 mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of TRIB1 mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of TRIM36 mRNA	19059307
D020849	Raloxifene Hydrochloride	"Raloxifene Hydrochloride inhibits the reaction [3,3'-diindolylmethane results in increased expression of ESR2 mRNA]"	20160136
D020849	Raloxifene Hydrochloride	Raloxifene Hydrochloride promotes the reaction [ESR2 protein binds to IGF1 promoter]	17872375
D020849	Raloxifene Hydrochloride	Raloxifene Hydrochloride promotes the reaction [ESR2 protein binds to PTGS2 promoter]	17872375
D020849	Raloxifene Hydrochloride	Raloxifene Hydrochloride results in decreased activity of ESR2 protein	17654759
D020849	Raloxifene Hydrochloride	Raloxifene Hydrochloride results in increased activity of ESR2 protein	17962382
D020849	Raloxifene Hydrochloride	Raloxifene Hydrochloride binds to and affects the activity of ESR2 protein alternative form	15924412
D020849	Raloxifene Hydrochloride	ESR2 protein promotes the reaction [Raloxifene Hydrochloride results in increased expression of SLC1A2 mRNA]	24782323
D020849	Raloxifene Hydrochloride	ESR2 protein promotes the reaction [Raloxifene Hydrochloride results in increased expression of SLC1A3 mRNA]	24782323
D020849	Raloxifene Hydrochloride	Raloxifene Hydrochloride affects the expression of ESR2 mRNA	19350480
D020849	Raloxifene Hydrochloride	Raloxifene Hydrochloride affects the expression of ESR2 protein	15653758\|1668007
D017382	Reactive Oxygen Species	ESR2 protein promotes the reaction [Estradiol results in decreased abundance of Reactive Oxygen Species]	20463317
C059514	resveratrol	resveratrol inhibits the reaction [ESR2 protein binds to CAV1 protein]	18296501
C059514	resveratrol	ESR2 protein promotes the reaction [resveratrol analog results in decreased expression of MYC protein]	26970359
C059514	resveratrol	fulvestrant inhibits the reaction [resveratrol results in increased activity of ESR2 protein]	17935960
C059514	resveratrol	resveratrol analog binds to ESR2 protein	26970359
C059514	resveratrol	resveratrol analog results in increased expression of ESR2 mRNA	26970359
C059514	resveratrol	resveratrol analog results in increased expression of ESR2 protein	26970359
C059514	resveratrol	resveratrol binds to and results in decreased activity of ESR2 protein	15084758
C059514	resveratrol	resveratrol binds to and results in increased activity of ESR2 protein	12765243
C059514	resveratrol	resveratrol binds to ESR2 protein	11507064\|2124828
C059514	resveratrol	resveratrol inhibits the reaction [Estradiol binds to ESR2 protein]	11507064
C059514	resveratrol	resveratrol promotes the reaction [Estradiol results in increased activity of ESR2 protein]	16118406
C059514	resveratrol	resveratrol results in increased activity of ESR2 protein	16118406\|1793596
C059514	resveratrol	resveratrol results in increased expression of ESR2 mRNA	15149879\|2697035
C059514	resveratrol	resveratrol results in increased expression of ESR2 protein	24299158\|2524245
C059514	resveratrol	ESR2 gene mutant form inhibits the reaction [resveratrol results in increased expression of SOD2 protein]	24361291
C059514	resveratrol	ESR2 protein affects the reaction [resveratrol results in increased expression of SOD2 protein]	23526725
C059514	resveratrol	ESR2 protein affects the susceptibility to resveratrol	23526725
C059514	resveratrol	resveratrol results in increased expression of ESR2 protein	17675339
C059514	resveratrol	"[2,3-bis(4-hydroxyphenyl)-propionitrile binds to and results in increased activity of ESR2 protein] inhibits the reaction [resveratrol results in decreased expression of PRL protein]"	22104698
C059514	resveratrol	resveratrol affects the reaction [Oxygen deficiency affects the expression of ESR2 mRNA]	24333797
C059514	resveratrol	resveratrol affects the reaction [Oxygen deficiency affects the expression of ESR2 protein]	24333797
C059514	resveratrol	resveratrol binds to and results in increased activity of ESR2 protein	11014220
C059514	resveratrol	resveratrol binds to ESR2 protein	11014220
C059514	resveratrol	resveratrol inhibits the reaction [Oxygen deficiency results in decreased expression of ESR2 mRNA]	24333797
C059514	resveratrol	resveratrol inhibits the reaction [Oxygen deficiency results in decreased expression of ESR2 protein]	24333797
C059514	resveratrol	resveratrol results in decreased expression of ESR2 protein	22104698
C059514	resveratrol	resveratrol binds to ESR2 protein	16614383
D015474	Isotretinoin	Isotretinoin results in decreased expression of ESR2 mRNA	19041696
C431126	rhapontigenin	fulvestrant inhibits the reaction [rhapontigenin analog results in increased activity of ESR2 protein]	17692514\|1793596
C431126	rhapontigenin	rhapontigenin analog results in increased activity of ESR2 protein	17692514\|1793596
D012293	Rifampin	Rifampin results in increased expression of ESR2 mRNA	16713641
C018421	rifapentine	rifapentine binds to and results in decreased activity of ESR2 protein	25752796
C529148	rosavin	rosavin results in decreased expression of ESR2 mRNA	20706672
C089730	rosiglitazone	rosiglitazone binds to and results in increased activity of ESR2 protein	21622942
D012402	Rotenone	Rotenone binds to and results in decreased activity of ESR2 protein	25752796
C058787	royal jelly	Estradiol inhibits the reaction [royal jelly binds to ESR2 protein]	17287592
C058787	royal jelly	royal jelly binds to and results in increased activity of ESR2 protein	15946813
C058787	royal jelly	royal jelly binds to ESR2 protein	17287592
C058787	royal jelly	royal jelly inhibits the reaction [Estradiol binds to ESR2 protein]	15946813
C079905	rubitecan	rubitecan binds to and results in decreased activity of ESR2 protein	25752796
C005704	salicylaldoxime	salicylaldoxime analog binds to and results in increased activity of ESR2 protein	12954056
D012459	Salicylates	Salicylates analog binds to and results in decreased activity of ESR2 protein	12628652
D019258	Saquinavir	[Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of ESR2 mRNA	16931933
C093642	SB 203580	SB 203580 inhibits the reaction [[ESR2 protein results in increased susceptibility to Estradiol] which results in increased cleavage of CASP3 protein]	21732360
C093642	SB 203580	SB 203580 inhibits the reaction [[ESR2 protein results in increased susceptibility to Estradiol] which results in increased cleavage of PARP1 protein]	21732360
C093642	SB 203580	SB 203580 inhibits the reaction [[ESR2 protein results in increased susceptibility to Quercetin] which results in increased cleavage of CASP3 protein]	21732360
C093642	SB 203580	SB 203580 inhibits the reaction [[ESR2 protein results in increased susceptibility to Quercetin] which results in increased cleavage of PARP1 protein]	21732360
D020845	Selective Estrogen Receptor Modulators	Selective Estrogen Receptor Modulators binds to ESR2 protein	18559275
D020845	Selective Estrogen Receptor Modulators	Selective Estrogen Receptor Modulators results in increased activity of ESR2 protein	18559275
D020845	Selective Estrogen Receptor Modulators	Selective Estrogen Receptor Modulators binds to and results in increased activity of ESR2 protein	18559275
D012645	Selenomethionine	Selenomethionine results in decreased expression of ESR2 mRNA	21762653
C440975	silybin	silybin results in increased activity of [ESR1 protein binds to ESR2 protein]	16076518
C440975	silybin	silybin results in increased activity of [ESR1 protein binds to ESR2 protein]	16076518
D012838	Silymarin	Silymarin results in increased activity of [ESR1 protein binds to ESR2 protein]	16076518
D012838	Silymarin	Silymarin inhibits the reaction [Testosterone results in decreased expression of ESR2 protein]	23500659
D012838	Silymarin	Silymarin results in increased activity of [ESR1 protein binds to ESR2 protein]	16076518
C017947	sodium arsenite	sodium arsenite affects the expression of ESR2 mRNA	29319823
C017947	sodium arsenite	sodium arsenite results in increased expression of ESR2 protein	25728338
D012973	Sodium Hypochlorite	Sodium Hypochlorite inhibits the reaction [bisphenol A binds to ESR2 protein]	14723943
D012973	Sodium Hypochlorite	Sodium Hypochlorite inhibits the reaction [Estradiol binds to ESR2 protein]	14723943
D012973	Sodium Hypochlorite	Sodium Hypochlorite inhibits the reaction [nonylphenol binds to ESR2 protein]	14723943
D018038	Sodium Selenite	Sodium Selenite affects the expression of ESR2 mRNA	16928829
D012989	Soil Pollutants	Soil Pollutants results in increased activity of ESR2 protein polymorphism	28013213
D019311	Staurosporine	Staurosporine binds to and results in decreased activity of ESR2 protein	25752796
D013311	Streptozocin	bisphenol A inhibits the reaction [Streptozocin results in decreased expression of ESR2 mRNA]	24781736
D013311	Streptozocin	Ethinyl Estradiol inhibits the reaction [Streptozocin results in decreased expression of ESR2 mRNA]	24781736
D013311	Streptozocin	octylphenol inhibits the reaction [Streptozocin results in decreased expression of ESR2 mRNA]	24781736
D013311	Streptozocin	Streptozocin results in decreased expression of ESR2 mRNA	24781736
D014284	Triiodothyronine	[Arsenic co-treated with Estradiol co-treated with Triiodothyronine] results in decreased expression of ESR2 mRNA	27338438
D014284	Triiodothyronine	[bisphenol A co-treated with Estradiol co-treated with Triiodothyronine] results in increased expression of ESR2 mRNA	27338438
D014284	Triiodothyronine	[bisphenol A co-treated with Zearalenone co-treated with Arsenic co-treated with enzacamene co-treated with Estradiol co-treated with Triiodothyronine] results in decreased expression of ESR2 mRNA	27338438
D014284	Triiodothyronine	[bisphenol A results in increased susceptibility to [Estradiol co-treated with Triiodothyronine]] which results in increased expression of ESR2 mRNA	27338438
D014284	Triiodothyronine	[enzacamene co-treated with Estradiol co-treated with Triiodothyronine] affects the expression of ESR2 mRNA	27338438
D014284	Triiodothyronine	[Estradiol co-treated with Triiodothyronine] inhibits the reaction [bisphenol A results in decreased expression of ESR2 mRNA]	27338438
D014284	Triiodothyronine	[Estradiol co-treated with Triiodothyronine] promotes the reaction [Zearalenone results in decreased expression of ESR2 mRNA]	27338438
D014284	Triiodothyronine	[Zearalenone co-treated with Estradiol co-treated with Triiodothyronine] results in decreased expression of ESR2 mRNA	27338438
D014284	Triiodothyronine	[Zearalenone results in increased susceptibility to [Estradiol co-treated with Triiodothyronine]] which results in decreased expression of ESR2 mRNA	27338438
D013629	Tamoxifen	CXCL12 protein promotes the reaction [Tamoxifen promotes the reaction [ESR2 protein binds to CCND1 promoter]]	19584281
D013629	Tamoxifen	ESR2 protein affects the reaction [Tamoxifen results in decreased expression of F13A1 mRNA]	14699072
D013629	Tamoxifen	ESR2 protein affects the reaction [Tamoxifen results in decreased expression of IVL mRNA]	14699072
D013629	Tamoxifen	ESR2 protein affects the reaction [Tamoxifen results in decreased expression of KLRC3 mRNA]	14699072
D013629	Tamoxifen	ESR2 protein affects the reaction [Tamoxifen results in decreased expression of MAFF mRNA]	14699072
D013629	Tamoxifen	ESR2 protein affects the reaction [Tamoxifen results in decreased expression of PTPRH mRNA]	14699072
D013629	Tamoxifen	ESR2 protein affects the reaction [Tamoxifen results in increased expression of NNMT mRNA]	14699072
D013629	Tamoxifen	ESR2 protein affects the reaction [Tamoxifen results in increased expression of PTPRO mRNA]	19095770
D013629	Tamoxifen	ESR2 protein affects the susceptibility to Tamoxifen	19434490
D013629	Tamoxifen	ESR2 protein promotes the reaction [Tamoxifen results in increased expression of BIK protein]	17638070
D013629	Tamoxifen	ESR2 protein results in decreased susceptibility to Tamoxifen	16010412
D013629	Tamoxifen	ESR2 protein results in increased susceptibility to Tamoxifen	15821116\|1763807
D013629	Tamoxifen	Plant Extracts promotes the reaction [Tamoxifen inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ESR2 mRNA]]	20559769
D013629	Tamoxifen	Tamoxifen binds to and results in decreased activity of ESR2 protein	25752796
D013629	Tamoxifen	Tamoxifen binds to and results in increased activity of ESR2 protein	19059307
D013629	Tamoxifen	Tamoxifen binds to ESR2 protein	11518614\|1222463
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in decreased expression of ABCC1 mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in decreased expression of ACKR3 mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in decreased expression of ACSL1 mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in decreased expression of AGO2 mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in decreased expression of AKAP1 mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in decreased expression of ARL4C mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in decreased expression of ASB13 mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in decreased expression of C14ORF132 mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in decreased expression of C2CD2 mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in decreased expression of CA12 mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in decreased expression of CALM1 mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in decreased expression of CASKIN2 mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in decreased expression of CASP7 mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in decreased expression of CCND1 mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in decreased expression of CDK5R1 mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in decreased expression of CEBPB mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in decreased expression of CERS6 mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in decreased expression of CLCN4 mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in decreased expression of CRISPLD2 mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in decreased expression of CSDC2 mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in decreased expression of CUEDC1 mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in decreased expression of CYP19A1 mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in decreased expression of CYP24A1 mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in decreased expression of CYP26B1 mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in decreased expression of DOCK9 mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in decreased expression of EDNRA mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in decreased expression of ELF3 mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in decreased expression of ENDOD1 mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in decreased expression of EVI2A mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in decreased expression of FADD mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in decreased expression of FGD6 mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in decreased expression of FGFR2 mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in decreased expression of FHL2 mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in decreased expression of FLNB mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in decreased expression of FOSL2 mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in decreased expression of FOXO1 mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in decreased expression of FST mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in decreased expression of GPRC5C mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in decreased expression of HEG1 mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in decreased expression of HK1 mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in decreased expression of HMOX1 mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in decreased expression of HPCAL1 mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in decreased expression of HSPB8 mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in decreased expression of HTR3A mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in decreased expression of INPP5A mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in decreased expression of IVL mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in decreased expression of KAZN mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in decreased expression of KCTD12 mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in decreased expression of KIF3C mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in decreased expression of KLRC3 mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in decreased expression of KLRK1 mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in decreased expression of LBH mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in decreased expression of LMNB2 mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in decreased expression of LRIG1 mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in decreased expression of LRRC20 mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in decreased expression of LYSMD4 mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in decreased expression of MAFF mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in decreased expression of MAGEA8 mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in decreased expression of MAP3K5 mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in decreased expression of MAP3K8 mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in decreased expression of MAPKAPK2 mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in decreased expression of MBNL2 mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in decreased expression of MDFIC mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in decreased expression of MEF2A mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in decreased expression of MMP12 mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in decreased expression of MN1 mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in decreased expression of MPPED2 mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in decreased expression of MYT1L mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in decreased expression of NAV2 mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in decreased expression of NCF2 mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in decreased expression of NCOA1 mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in decreased expression of NCOA4 mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in decreased expression of NDRG4 mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in decreased expression of NFATC1 mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in decreased expression of NFIL3 mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in decreased expression of NFKBIA mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in decreased expression of NINJ1 mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in decreased expression of NPR2 mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in decreased expression of NR1D1 mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in decreased expression of NR2F6 mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in decreased expression of NUAK1 mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in decreased expression of OSBPL3 mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in decreased expression of OTUB2 mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in decreased expression of PCTP mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in decreased expression of PDLIM3 mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in decreased expression of PHC2 mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in decreased expression of PHF11 mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in decreased expression of PITPNC1 mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in decreased expression of PRKCZ mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in decreased expression of PTGER3 mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in decreased expression of PTGES mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in decreased expression of RCOR3 mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in decreased expression of RET mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in decreased expression of RETREG1 mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in decreased expression of RFTN1 mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in decreased expression of RGL1 mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in decreased expression of RHOF mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in decreased expression of RPS6KA2 mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in decreased expression of SALL1 mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in decreased expression of SCNN1A mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in decreased expression of SEMA3F mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in decreased expression of SERPINB6 mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in decreased expression of SLC18A3 mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in decreased expression of SREBF1 mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in decreased expression of SSH1 mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in decreased expression of ST3GAL1 mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in decreased expression of STK24 mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in decreased expression of SYBU mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in decreased expression of SYNJ2 mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in decreased expression of SYNPO mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in decreased expression of TACC1 mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in decreased expression of TACC2 mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in decreased expression of TBXA2R mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in decreased expression of TGFA mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in decreased expression of TMOD1 mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in decreased expression of TNS3 mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in decreased expression of TOB1 mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in decreased expression of TRAF3IP2 mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in decreased expression of UPF1 mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in decreased expression of WNT5A mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in decreased expression of ZCCHC24 mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in decreased expression of ZMIZ1 mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in decreased expression of ZNF395 mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in increased expression of ADAM19 mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in increased expression of ADORA2B mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in increased expression of AMIGO2 mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in increased expression of ANKRD1 mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in increased expression of AREG mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in increased expression of ATF3 mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in increased expression of BIRC3 mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in increased expression of CCL20 mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in increased expression of CCL2 mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in increased expression of CDH2 mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in increased expression of CDO1 mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in increased expression of CXCL12 mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in increased expression of CXCL8 mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in increased expression of DACT1 mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in increased expression of DCBLD2 mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in increased expression of DUSP2 mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in increased expression of DUSP5 mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in increased expression of EGFR mRNA	19347870
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in increased expression of EGFR protein	19347870
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in increased expression of EGR1 mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in increased expression of ENC1 mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in increased expression of FUT9 mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in increased expression of GAD1 mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in increased expression of GRB10 mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in increased expression of GYG1 mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in increased expression of HBEGF mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in increased expression of ID4 mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in increased expression of IFNGR2 mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in increased expression of INHBA mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in increased expression of JAG1 mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in increased expression of KRT17 mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in increased expression of KRT34 mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in increased expression of LDLRAD4 mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in increased expression of LMCD1 mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in increased expression of MAP2K3 mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in increased expression of NAB1 mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in increased expression of NFKBIE mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in increased expression of NR3C1 mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in increased expression of NR4A3 mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in increased expression of OCLN mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in increased expression of PCDH7 mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in increased expression of PDP1 mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in increased expression of PTGS2 mRNA	19059307\|1934787
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in increased expression of PTP4A3 mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in increased expression of PTX3 mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in increased expression of RASGRP1 mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in increased expression of RCAN2 mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in increased expression of RFK mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in increased expression of RGS4 mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in increased expression of RRAD mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in increased expression of SERPINE1 mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in increased expression of SLCO4C1 mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in increased expression of SOD2 mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in increased expression of TCIM mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in increased expression of TGFB2 mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in increased expression of TGFBI mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in increased expression of TMEM158 mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in increased expression of TNC mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in increased expression of TNFRSF11B mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in increased expression of TNFRSF21 mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in increased expression of TNIK mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in increased expression of TRAF5 mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in increased expression of TRIB1 mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in increased expression of TRIM36 mRNA	19059307
D013629	Tamoxifen	"Tamoxifen inhibits the reaction [3,3'-diindolylmethane results in increased expression of ESR2 mRNA]"	20160136
D013629	Tamoxifen	Tamoxifen inhibits the reaction [Estradiol results in increased activity of ESR2 protein]	19672399\|2677835
D013629	Tamoxifen	Tamoxifen inhibits the reaction [Estradiol results in increased expression of ESR2 mRNA]	12377985
D013629	Tamoxifen	Tamoxifen inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ESR2 mRNA]	20559769
D013629	Tamoxifen	Tamoxifen metabolite binds to ESR2 protein	15135306
D013629	Tamoxifen	Tamoxifen promotes the reaction [ESR1 protein binds to ESR2 protein]	20061804
D013629	Tamoxifen	Tamoxifen promotes the reaction [ESR2 protein binds to CCND1 promoter]	19584281
D013629	Tamoxifen	Tamoxifen promotes the reaction [ESR2 protein binds to [[FOS protein binds to JUN protein] which binds to PTPRO promoter]]	19095770
D013629	Tamoxifen	Tamoxifen results in decreased expression of ESR2 protein	16202921
D013629	Tamoxifen	Tamoxifen results in increased expression of ESR2 protein	16739346
D013629	Tamoxifen	Linseed Oil inhibits the reaction [Tamoxifen results in decreased expression of ESR2 mRNA]	21138602
D013629	Tamoxifen	Tamoxifen binds to ESR2 protein	19913605
D013629	Tamoxifen	Tamoxifen results in decreased expression of ESR2 mRNA	21138602
D013629	Tamoxifen	Tamoxifen results in increased expression of ESR2 protein	19279558
D013629	Tamoxifen	[Estradiol co-treated with Tamoxifen] results in increased expression of ESR2 mRNA	17823450
D013629	Tamoxifen	Tamoxifen results in increased expression of ESR2 mRNA	17823450
D013629	Tamoxifen	[Estradiol co-treated with Tamoxifen] results in increased expression of ESR2 protein	19460436
D013629	Tamoxifen	Tamoxifen binds to ESR2 protein	19913605
D013629	Tamoxifen	Tamoxifen inhibits the reaction [16 alpha-iodoestradiol binds to ESR2 protein]	9048584
D013629	Tamoxifen	Tamoxifen inhibits the reaction [ESR2 protein binds to H19 gene]	19683557
D013629	Tamoxifen	Tamoxifen inhibits the reaction [ESR2 protein binds to NCOA1 protein]	19460436
D013629	Tamoxifen	Tamoxifen inhibits the reaction [Estradiol binds to ESR2 protein alternative form]	9492041
D013629	Tamoxifen	Tamoxifen inhibits the reaction [Estradiol results in increased activity of ESR2 protein]	8650195
D013629	Tamoxifen	Tamoxifen results in increased expression of ESR2 mRNA	12834913
D013629	Tamoxifen	"Tamoxifen inhibits the reaction [[4-nonylphenol co-treated with 3,4,3',4'-tetrachlorobiphenyl] results in decreased expression of ESR2 mRNA]"	17291011
D013629	Tamoxifen	Tamoxifen binds to ESR2 protein	19913605
D013629	Tamoxifen	ESR2 gene modified form affects the susceptibility to Tamoxifen	24169358
D013629	Tamoxifen	Tamoxifen binds to and results in decreased activity of ESR2 protein	21843587
D013713	Teniposide	Teniposide binds to and results in decreased activity of ESR2 protein	25752796
D013739	Testosterone	Testosterone binds to ESR2 protein	19913605
D013739	Testosterone	Testosterone results in decreased expression of ESR2 protein	15916834
D013739	Testosterone	Testosterone results in increased expression of ESR2 mRNA	20844152
D013739	Testosterone	Testosterone results in increased expression of ESR2 protein	15916834
D013739	Testosterone	Metformin inhibits the reaction [Testosterone results in decreased expression of ESR2 mRNA]	26492952
D013739	Testosterone	Qing Ye Dan inhibits the reaction [Testosterone results in decreased expression of ESR2 protein]	27866977
D013739	Testosterone	Silymarin inhibits the reaction [Testosterone results in decreased expression of ESR2 protein]	23500659
D013739	Testosterone	Testosterone results in decreased expression of ESR2 mRNA	26492952
D013739	Testosterone	Testosterone results in decreased expression of ESR2 protein	23500659\|2786697
D013739	Testosterone	Testosterone results in increased expression of ESR2 mRNA	15917159
D013739	Testosterone	Testosterone binds to ESR2 protein	19913605
C020806	tetrabromobisphenol A	tetrabromobisphenol A affects the expression of ESR2 mRNA	26988606\|2830066
C041181	tetrachlorodian	tetrachlorodian binds to and results in increased activity of ESR2 protein	21622942
C041181	tetrachlorodian	tetrachlorodian results in increased activity of ESR2 protein	21561829
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin inhibits the reaction [Cycloheximide promotes the reaction [Estradiol results in increased expression of ESR2 mRNA]]	15207704
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin inhibits the reaction [ESR1 protein binds to ESR2 promoter]	15207704
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin inhibits the reaction [Estradiol results in increased expression of ESR2 mRNA]	15207704
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin inhibits the reaction [Estradiol results in increased expression of ESR2 mRNA mutant form]	15207704
D013749	Tetrachlorodibenzodioxin	[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of ESR2 mRNA	17942748
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin results in decreased activity of ESR2 protein	17991765
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin results in decreased expression of ESR2 mRNA	24058054
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin results in increased expression of ESR2 mRNA	11500237\|1222322
D013755	Tetradecanoylphorbol Acetate	Ethinyl Estradiol inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of ESR2 protein]	10633228
D013755	Tetradecanoylphorbol Acetate	Plant Extracts inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ESR2 mRNA]	20559769
D013755	Tetradecanoylphorbol Acetate	Plant Extracts promotes the reaction [Tamoxifen inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ESR2 mRNA]]	20559769
D013755	Tetradecanoylphorbol Acetate	Tamoxifen inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ESR2 mRNA]	20559769
D013755	Tetradecanoylphorbol Acetate	Tetradecanoylphorbol Acetate results in decreased expression of ESR2 protein	10633228
D013755	Tetradecanoylphorbol Acetate	Tetradecanoylphorbol Acetate results in increased expression of ESR2 mRNA	20559769
C005807	tetradifon	tetradifon results in increased activity of ESR2 protein	26139245
C433164	tetrahydrodaidzein	Estradiol affects the reaction [tetrahydrodaidzein affects the activity of ESR2 protein]	16965913
C095210	tetralin	tetralin analog results in decreased activity of ESR2 protein	15737489
C095210	tetralin	tetralin analog results in increased activity of ESR2 protein	15737489
C009424	tetramethrin	tetramethrin results in increased expression of ESR2 protein	16326440
C027385	tibolone	tibolone metabolite results in increased activity of ESR2 protein	16720731
C027385	tibolone	tibolone results in increased activity of ESR2 protein	16720731
C426783	tolclofos-methyl	tolclofos-methyl results in increased activity of ESR2 protein	15064155
D017312	Toremifene	Toremifene binds to and results in decreased activity of ESR2 protein	25752796
D017312	Toremifene	Toremifene results in increased expression of ESR2 mRNA	12079510
D014112	Toxaphene	Toxaphene binds to and results in increased activity of ESR2 protein	16626760
D014112	Toxaphene	Toxaphene results in increased activity of ESR2 protein	9860891
C036101	tri-(2-ethylhexyl)trimellitate	tri-(2-ethylhexyl)trimellitate promotes the reaction [Estradiol results in increased activity of ESR2 protein]	16756374
C036101	tri-(2-ethylhexyl)trimellitate	tri-(2-ethylhexyl)trimellitate results in increased activity of ESR2 protein	16756374
C011559	tributyltin	tributyltin results in decreased expression of ESR2 mRNA	16318860
C011559	tributyltin	tributyltin affects the expression of ESR2 protein	28161095
C011559	tributyltin	tributyltin results in increased expression of ESR2 mRNA	23850073
C012589	trichostatin A	[decitabine co-treated with trichostatin A] results in decreased methylation of ESR2 promoter	19331143
C012589	trichostatin A	[decitabine co-treated with trichostatin A] results in increased expression of ESR2 mRNA	19331143
C012589	trichostatin A	decitabine promotes the reaction [trichostatin A results in increased expression of ESR2 mRNA]	18092350
C012589	trichostatin A	decitabine promotes the reaction [trichostatin A results in increased expression of ESR2 protein]	18092350
C012589	trichostatin A	trichostatin A promotes the reaction [Estradiol results in increased activity of ESR2 protein]	15103026
C012589	trichostatin A	trichostatin A results in decreased methylation of ESR2 promoter	19331143
C012589	trichostatin A	trichostatin A results in increased expression of ESR2 mRNA	18092350\|1933114
C012589	trichostatin A	trichostatin A results in increased expression of ESR2 protein	18092350
D014260	Triclosan	Triclosan inhibits the reaction [Estradiol binds to ESR2 protein]	17992702
D014260	Triclosan	[Ethinyl Estradiol co-treated with Triclosan] results in decreased expression of ESR2 mRNA	23261820
D014260	Triclosan	fulvestrant inhibits the reaction [[Ethinyl Estradiol co-treated with Triclosan] results in decreased expression of ESR2 mRNA]	23261820
C009954	trilostane	trilostane results in increased expression of ESR2 mRNA	20981412
C005445	triphenyl phosphate	triphenyl phosphate metabolite inhibits the reaction [Estradiol results in increased activity of ESR2 protein]	26778350
C005445	triphenyl phosphate	triphenyl phosphate metabolite results in increased activity of ESR2 protein	26778350
C005445	triphenyl phosphate	triphenyl phosphate results in increased activity of ESR2 protein	26778350
C482068	TS 108	TS 108 binds to and results in increased activity of ESR2 protein	15671561
C482068	TS 108	TS 108 binds to ESR2 protein	15671561
C526928	undecan-2-one	undecan-2-one binds to and results in decreased activity of ESR2 protein	27633901
D058425	Vaccines, Virus-Like Particle	"Vaccines, Virus-Like Particle results in increased expression of ESR2 mRNA"	20130130
D014634	Valinomycin	Valinomycin binds to and results in decreased activity of ESR2 protein	25752796
D014635	Valproic Acid	Valproic Acid metabolite promotes the reaction [Estradiol results in increased activity of ESR2 protein]	23892311
D014635	Valproic Acid	Valproic Acid metabolite results in increased activity of ESR2 protein	23892311
D014635	Valproic Acid	Valproic Acid promotes the reaction [Estradiol results in increased activity of ESR2 protein]	15103026\|2389231
D014635	Valproic Acid	Valproic Acid results in increased activity of ESR2 protein	23892311
D001335	Vehicle Emissions	Vehicle Emissions results in decreased methylation of ESR2 gene	25560391
D001335	Vehicle Emissions	Vehicle Emissions results in increased expression of ESR2 mRNA	19629445
C059141	verlukast	verlukast binds to and results in decreased activity of ESR2 protein	25752796
C023054	versalide	versalide binds to and results in decreased activity of ESR2 protein	15537743
C025643	vinclozolin	vinclozolin binds to and results in increased activity of ESR2 protein	16626760\|1675084
C025643	vinclozolin	vinclozolin results in decreased expression of ESR2 mRNA	16504050
C025643	vinclozolin	vinclozolin results in decreased expression of ESR2 mRNA	17980475\|2257069
C025643	vinclozolin	vinclozolin results in increased expression of ESR2 mRNA	17980475
C017963	vinyl carbamate	vinyl carbamate results in decreased expression of ESR2 mRNA	17849452
D014873	Water Pollutants	Water Pollutants results in decreased expression of ESR2 mRNA	22856545
C499198	WAY-169916	WAY-169916 binds to ESR2 protein	20423157
C518540	Y134 compound	Y134 compound binds to and results in decreased activity of ESR2 protein	17115070
D015029	Zeranol	Zeranol binds to ESR2 protein	19913605
D015215	Zidovudine	[Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in decreased expression of ESR2 mRNA	16931933
D015215	Zidovudine	[Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of ESR2 mRNA	16931933

GO/Pathway

GO ID	GO Term	Qualifier	Evidence	PubMed
GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding	-	IDA	15345745
GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding	-	ISA	-
GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding	-	ISM	19274049
GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding	-	NAS	19274049
GO:0003677	DNA binding	-	TAS	9636657
GO:0003700	DNA-binding transcription factor activity	-	TAS	8769313
GO:0003707	steroid hormone receptor activity	-	TAS	10749889
GO:0003713	transcription coactivator activity	-	TAS	8769313
GO:0004879	nuclear receptor activity	-	NAS	9671811
GO:0005496	steroid binding	-	ISS	-
GO:0005496	steroid binding	-	TAS	11181953
GO:0005515	protein binding	-	IPI	11279242 14764652 15199063 19022902 19126643 20074560 25416956
GO:0008270	zinc ion binding	-	IEA	-
GO:0019899	enzyme binding	-	IPI	12039952
GO:0030284	estrogen receptor activity	-	TAS	11181953
GO:0034056	estrogen response element binding	-	IDA	15345745 19126643
GO:0038052	RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding	-	IDA	19126643
GO:0042802	identical protein binding	-	IPI	19022902 21182203
GO:0048019	receptor antagonist activity	-	NAS	9671811

GO ID	GO Term	Qualifier	Evidence	PubMed
GO:0000122	negative regulation of transcription by RNA polymerase II	-	IDA	15345745
GO:0006355	regulation of transcription, DNA-templated	-	TAS	11181953
GO:0006367	transcription initiation from RNA polymerase II promoter	-	TAS	-
GO:0007165	signal transduction	-	TAS	8769313 10749889
GO:0007267	cell-cell signaling	-	TAS	8769313
GO:0030308	negative regulation of cell growth	-	NAS	11181953
GO:0030520	intracellular estrogen receptor signaling pathway	-	TAS	11181953
GO:0045893	positive regulation of transcription, DNA-templated	-	IDA	20074560
GO:0051091	positive regulation of DNA-binding transcription factor activity	-	IDA	10681512
GO:1900116	extracellular negative regulation of signal transduction	-	IEA	-

GO ID	GO Term	Qualifier	Evidence	PubMed
GO:0005576	extracellular region	-	IEA	-
GO:0005634	nucleus	-	IDA	19126643 20074560
GO:0005634	nucleus	-	TAS	11181953
GO:0005654	nucleoplasm	-	TAS	-
GO:0005739	mitochondrion	-	IDA	15024130

KEGG ID	KEGG Term

Reactome ID	Reactome Term	Evidence
R-HSA-1257604	PIP3 activates AKT signaling	TAS
R-HSA-162582	Signal Transduction	TAS
R-HSA-1643685	Disease	TAS
R-HSA-199418	Negative regulation of the PI3K/AKT network	TAS
R-HSA-212436	Generic Transcription Pathway	TAS
R-HSA-2219528	PI3K/AKT Signaling in Cancer	TAS
R-HSA-2219530	Constitutive Signaling by Aberrant PI3K in Cancer	TAS
R-HSA-383280	Nuclear Receptor transcription pathway	TAS
R-HSA-5663202	Diseases of signal transduction	TAS
R-HSA-6811558	PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling	TAS
R-HSA-73857	RNA Polymerase II Transcription	TAS
R-HSA-74160	Gene expression (Transcription)	TAS
R-HSA-8939211	ESR-mediated signaling	TAS
R-HSA-9006925	Intracellular signaling by second messengers	TAS
R-HSA-9006931	Signaling by Nuclear Receptors	TAS

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID	Title (Year)	Author	Journal
20346360	Genetic risk factors for hepatopulmonary syndrome in patients with advanced liver disease. (2010 Jul)	Roberts KE	Gastroenterology
23197595	Steroidogenic enzyme expression in the human fetal liver and potential role in the endocrinology of pregnancy. (2013 Mar)	O'Shaughnessy PJ	Mol Hum Reprod
20655613	Haplotypes of estrogen receptor-beta and risk of non-small cell lung cancer in women. (2011 Mar)	Paulus JK	Lung Cancer
26251204	Associations between estrogen receptor genetic polymorphisms, smoking status, and prostate cancer risk: a case-control study in Japanese men. (2015 Sep)	Lu X	Environ Health Prev Med
22583357	Oestrogen receptor beta in NSCLC - prevalence, proliferative influence, prognostic impact and smoking. (2012 Jun)	Karlsson C	APMIS
19948975	Integrative predictive model of coronary artery calcification in atherosclerosis. (2009 Dec 15)	McGeachie M	Circulation
25030786	Risk for estrogen-dependent diseases in relation to phthalate exposure and polymorphisms of CYP17A1 and estrogen receptor genes. (2014 Dec)	Huang PC	Environ Sci Pollut Res Int
25650184	Associations between Environmental Exposures and Incident Colorectal Cancer by ESR2 Protein Expression Level in a Population-Based Cohort of Older Women. (2015 Apr)	Tillmans LS	Cancer Epidemiol Biomarkers Prev
26301798	Estrogen Receptor Gene Polymorphisms and Lung Adenocarcinoma Risk in Never-Smoking Women. (2015 Oct)	Chen KY	J Thorac Oncol
19630952	Sex steroid metabolism polymorphisms and mammographic density in pre- and early perimenopausal women. (2009)	Crandall CJ	Breast Cancer Res
24847019	In utero exposure to cigarette smoke dysregulates human fetal ovarian developmental signalling. (2014 Jul)	Fowler PA	Hum Reprod
17941906	Polymorphism of the oestrogen receptor beta gene (ESR2) is associated with susceptibility to Graves' disease. (2008 Mar)	Kisiel B	Clin Endocrinol (Oxf)