Gene: ALCAM

214
CD166|MEMD
activated leukocyte cell adhesion molecule
protein-coding
3q13.11
Ensembl:ENSG00000170017 MIM:601662 Vega:OTTHUMG00000159192 UniprotKB:Q13740
NG_029729.1
PubMed
CD|ND
2   
NA (AD)  NA (ND)   (Frontal_Cortex)
2.822e-1 (AD)  5.066e-1 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
LRRC8D0.873
SPAST0.868
EDIL30.867
SLC35A50.866
GNAI10.859
DYNC1I20.854
RNF130.853
ABHD17B0.849
UBL30.846
FAR10.843

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
OR4F5-0.612
OR4F29-0.577
MTRNR2L6-0.265
CA1-0.264
MTRNR2L10-0.263
SLC4A1-0.26
TRIM10-0.252
AHSP-0.251
MTRNR2L8-0.247
MTRNR2L2-0.243

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C0493251,2-dithiol-3-thione"1,2-dithiol-3-thione results in decreased expression of ALCAM mRNA"19162173
C0326681-nitropyrene1-nitropyrene results in increased expression of ALCAM mRNA19041380
C1111182',3,3',4',5-pentachloro-4-hydroxybiphenyl"2',3,3',4',5-pentachloro-4-hydroxybiphenyl results in decreased expression of ALCAM mRNA"19114083
C0140242,4,5,2',4',5'-hexachlorobiphenyl"[3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] results in decreased expression of ALCAM mRNA"16984957
C0109142,4-diaminotoluene"2,4-diaminotoluene results in increased expression of ALCAM mRNA"20713471
C0164032,4-dinitrotoluene"2,4-dinitrotoluene affects the expression of ALCAM mRNA"21346803
C0235142,6-dinitrotoluene"2,6-dinitrotoluene results in increased expression of ALCAM mRNA"20406850
C0235142,6-dinitrotoluene"2,6-dinitrotoluene affects the expression of ALCAM mRNA"21346803
C0230353,4,5,3',4'-pentachlorobiphenyl"[3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] results in decreased expression of ALCAM mRNA"16984957
C0230353,4,5,3',4'-pentachlorobiphenyl"3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ALCAM mRNA"20959002
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide results in increased expression of ALCAM protein"25670856
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with mercuric bromide co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ALCAM mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with panobinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ALCAM mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ALCAM mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ALCAM mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ALCAM mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with vorinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ALCAM mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with mercuric bromide co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ALCAM mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with panobinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ALCAM mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ALCAM mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ALCAM mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ALCAM mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with vorinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ALCAM mRNA"27188386
D000082AcetaminophenAcetaminophen results in decreased expression of ALCAM mRNA21420995
D000082AcetaminophenAcetaminophen affects the expression of ALCAM mRNA17562736
D016604Aflatoxin B1Aflatoxin B1 results in decreased methylation of ALCAM gene27153756
D000643Ammonium ChlorideAmmonium Chloride affects the expression of ALCAM mRNA16483693
D018501Antirheumatic AgentsAntirheumatic Agents results in decreased expression of ALCAM mRNA24449571
D001564Benzo(a)pyreneBenzo(a)pyrene results in decreased expression of ALCAM mRNA19770486
D0151237,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide"7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of ALCAM mRNA"19150397
D004958EstradiolEstradiol affects the expression of ALCAM mRNA14699072
D004958Estradiol[Estradiol co-treated with Tetrachlorodibenzodioxin] results in increased expression of ALCAM mRNA19619570
D004958EstradiolEstradiol results in decreased expression of ALCAM mRNA19619570|2118537
D004958EstradiolRaloxifene Hydrochloride inhibits the reaction [Estradiol results in decreased expression of ALCAM mRNA]21185374
D004958EstradiolEstradiol results in increased expression of ALCAM mRNA15289156
D004958Estradiol[bisphenol A co-treated with Estradiol] results in increased expression of ALCAM mRNA26496021
C006780bisphenol Abisphenol A affects the expression of ALCAM mRNA20170705
C006780bisphenol A[bisphenol A co-treated with Estradiol] results in increased expression of ALCAM mRNA26496021
C006780bisphenol Abisphenol A results in increased expression of ALCAM protein24552547
C013418bromfenacoumbromfenacoum results in decreased expression of ALCAM protein28903499
C584509C646 compoundC646 compound results in decreased expression of ALCAM mRNA26191083
D002104CadmiumCadmium results in increased expression of ALCAM mRNA24067728
D019256Cadmium ChlorideCadmium Chloride results in increased expression of ALCAM mRNA26472689
D002251Carbon TetrachlorideCarbon Tetrachloride affects the expression of ALCAM mRNA17484886
D002251Carbon TetrachlorideCarbon Tetrachloride results in increased expression of ALCAM mRNA27339419
D002273CarcinogensCarcinogens results in increased expression of ALCAM mRNA16316942
D020111Chlorodiphenyl (54% Chlorine)Chlorodiphenyl (54% Chlorine) results in decreased expression of ALCAM mRNA18178546
C100187chloropicrinchloropicrin results in increased expression of ALCAM mRNA26352163
D004390ChlorpyrifosChlorpyrifos results in decreased expression of ALCAM mRNA18668222
D003033Coal TarCoal Tar results in decreased expression of ALCAM mRNA27858113
D003042CocaineCocaine results in increased expression of ALCAM mRNA17898221
D003375CoumestrolCoumestrol results in decreased expression of ALCAM mRNA19167446
D003520CyclophosphamideCyclophosphamide results in increased expression of ALCAM mRNA21041162
D016572CyclosporineCyclosporine results in decreased expression of ALCAM mRNA25562108|2798913
D016572CyclosporineCyclosporine affects the expression of ALCAM mRNA19770486
D013759DronabinolDronabinol results in increased expression of ALCAM mRNA15454482
D003907DexamethasoneDexamethasone results in increased expression of ALCAM mRNA21041162
D003993Dibutyl PhthalateDibutyl Phthalate results in increased expression of ALCAM mRNA17361019|2126653
D003993Dibutyl PhthalateDibutyl Phthalate results in decreased expression of ALCAM mRNA21266533
C000944dicrotophosdicrotophos results in decreased expression of ALCAM mRNA28302478
D004052DiethylnitrosamineDiethylnitrosamine results in increased expression of ALCAM mRNA24535843
D004054DiethylstilbestrolDiethylstilbestrol results in increased expression of ALCAM mRNA25242112
D004054DiethylstilbestrolDiethylstilbestrol results in increased expression of ALCAM mRNA15289156
D004237DiuronDiuron results in decreased expression of ALCAM mRNA21551480
D004791Enzyme Inhibitors[Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation of ALCAM protein23301498
D004997Ethinyl EstradiolEthinyl Estradiol results in increased expression of ALCAM mRNA17606305
D004997Ethinyl EstradiolEthinyl Estradiol results in increased expression of ALCAM mRNA17942748
D004997Ethinyl EstradiolEthinyl Estradiol affects the expression of ALCAM mRNA20170705
D004997Ethinyl EstradiolEthinyl Estradiol results in increased expression of ALCAM mRNA15834898|1755790
D005472FluorouracilALCAM protein affects the susceptibility to Fluorouracil15352031
D005472FluorouracilFluorouracil results in decreased expression of ALCAM protein15352031
D004397FonofosFonofos results in increased methylation of ALCAM promoter22847954
C056933fumonisin B1fumonisin B1 results in increased expression of ALCAM mRNA16221962
C546771gardiquimodgardiquimod results in increased expression of ALCAM mRNA28003376
C546771gardiquimodProtein Kinase Inhibitors inhibits the reaction [gardiquimod results in increased expression of ALCAM mRNA]28003376
D019833GenisteinGenistein results in increased expression of ALCAM mRNA15289156
D006533HeptachlorHeptachlor results in decreased expression of ALCAM mRNA23153324
D017313FenretinideFenretinide results in decreased expression of ALCAM mRNA28973697
D015759Ionomycin[Tetradecanoylphorbol Acetate co-treated with Ionomycin] affects the expression of ALCAM mRNA25613284
C544151jinfukangjinfukang results in decreased expression of ALCAM mRNA27392435
D007854LeadLead affects the splicing of ALCAM mRNA28903495
C008261lead acetatelead acetate results in increased expression of ALCAM mRNA21829687
D008070LipopolysaccharidesLipopolysaccharides results in decreased expression of ALCAM mRNA25613284
D058185Magnetite NanoparticlesMagnetite Nanoparticles results in decreased expression of ALCAM mRNA24525745
D058185Magnetite Nanoparticles[Succimer binds to Magnetite Nanoparticles] which results in decreased expression of ALCAM mRNA21641980
D017258Medroxyprogesterone AcetateMedroxyprogesterone Acetate results in increased expression of ALCAM mRNA18497975|2084394
C042720mercuric bromidemercuric bromide results in increased expression of ALCAM mRNA26272509
C042720mercuric bromide"[NOG protein co-treated with mercuric bromide co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ALCAM mRNA"27188386
D008748MethylcholanthreneMethylcholanthrene results in increased expression of ALCAM mRNA20713471
C004925methylmercuric chloridemethylmercuric chloride results in increased expression of ALCAM mRNA23103053
C004925methylmercuric chloridemethylmercuric chloride results in decreased expression of ALCAM mRNA28001369
C004925methylmercuric chloridemethylmercuric chloride results in increased expression of ALCAM mRNA23179753
C004925methylmercuric chloridemethylmercuric chloride affects the expression of ALCAM mRNA21613230
D008741Methyl MethanesulfonateMethyl Methanesulfonate results in decreased expression of ALCAM mRNA23649840
D0156551-Methyl-4-phenylpyridinium1-Methyl-4-phenylpyridinium results in decreased expression of ALCAM mRNA24810058
D016685MitomycinALCAM protein affects the susceptibility to Mitomycin16217747
C406082monomethylarsonous acidmonomethylarsonous acid results in decreased expression of ALCAM mRNA22108045
C500085muraglitazarmuraglitazar results in decreased expression of ALCAM mRNA21515302
C028473N-acetyl-4-benzoquinoneimineALCAM gene SNP affects the susceptibility to N-acetyl-4-benzoquinoneimine21177773
D037742Nanotubes, Carbon"Nanotubes, Carbon analog results in decreased expression of ALCAM mRNA"25554681
D037742Nanotubes, Carbon"Nanotubes, Carbon results in decreased expression of ALCAM mRNA"25554681|2562005
D037742Nanotubes, Carbon"Nanotubes, Carbon results in decreased secretion of ALCAM protein"25598225
C000621033napabucasinnapabucasin results in decreased expression of ALCAM mRNA25605917
C029938nickel sulfatenickel sulfate results in increased expression of ALCAM mRNA16780908
C012655nimesulidenimesulide results in decreased expression of ALCAM mRNA24136188
C014707nitrosobenzylmethylaminenitrosobenzylmethylamine results in increased expression of ALCAM mRNA17616710
C496932panobinostat"[NOG protein co-treated with panobinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ALCAM mRNA"27188386
C496932panobinostatpanobinostat results in increased expression of ALCAM mRNA26272509
D010278ParathionParathion results in increased methylation of ALCAM promoter22847954
C101814perfluoro-n-undecanoic acidperfluoro-n-undecanoic acid results in increased expression of ALCAM mRNA23602845
C076994perfluorooctane sulfonic acidperfluorooctane sulfonic acid results in decreased expression of ALCAM mRNA27153767
C076994perfluorooctane sulfonic acidperfluorooctane sulfonic acid results in decreased expression of ALCAM mRNA18692542
C023036perfluorooctanoic acidperfluorooctanoic acid results in decreased expression of ALCAM mRNA19162173
D010634PhenobarbitalPhenobarbital results in decreased expression of ALCAM mRNA23091169
D010662Phenylmercuric Acetate"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ALCAM mRNA"27188386
D010662Phenylmercuric AcetatePhenylmercuric Acetate results in increased expression of ALCAM mRNA26272509
C006253pirinixic acidpirinixic acid results in decreased expression of ALCAM mRNA23811191
C006253pirinixic acidpirinixic acid results in decreased expression of ALCAM mRNA19162173|2248451
D010936Plant ExtractsPlant Extracts results in increased expression of ALCAM mRNA23557933
D011374ProgesteroneProgesterone results in increased expression of ALCAM mRNA18497975|2179573
C045950propiconazolepropiconazole results in decreased expression of ALCAM mRNA21278054
D047428Protein Kinase InhibitorsProtein Kinase Inhibitors inhibits the reaction [gardiquimod results in increased expression of ALCAM mRNA]28003376
D054328Proton Pump InhibitorsProton Pump Inhibitors results in decreased expression of ALCAM mRNA25626140
D020849Raloxifene HydrochlorideRaloxifene Hydrochloride inhibits the reaction [Estradiol results in decreased expression of ALCAM mRNA]21185374
D015474IsotretinoinIsotretinoin results in decreased expression of ALCAM mRNA20436886
D012643SeleniumSelenium results in decreased expression of ALCAM mRNA19244175
D012834SilverSilver results in increased expression of ALCAM mRNA27131904
C009277sodium arsenatesodium arsenate results in increased expression of ALCAM mRNA21795629
C017947sodium arsenitesodium arsenite results in decreased expression of ALCAM protein21925251
D012969Sodium FluorideSodium Fluoride results in decreased expression of ALCAM protein28918527
D004113Succimer[Succimer binds to Magnetite Nanoparticles] which results in decreased expression of ALCAM mRNA21641980
D013629TamoxifenTamoxifen affects the expression of ALCAM mRNA14699072
C012568terbufosterbufos results in increased methylation of ALCAM promoter22847954
C501413tesaglitazartesaglitazar results in decreased expression of ALCAM mRNA21515302
C020806tetrabromobisphenol Atetrabromobisphenol A results in increased expression of ALCAM mRNA25172293
D013749Tetrachlorodibenzodioxin[Estradiol co-treated with Tetrachlorodibenzodioxin] results in increased expression of ALCAM mRNA19619570
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of ALCAM mRNA22298810
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased expression of ALCAM mRNA19619570|1968428
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of ALCAM mRNA19684285
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of ALCAM mRNA20067830
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of ALCAM mRNA21570461|2468072
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased expression of ALCAM mRNA19465110|1993321
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of ALCAM mRNA19684285|1977048
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased expression of ALCAM mRNA21215274
D013755Tetradecanoylphorbol Acetate[Tetradecanoylphorbol Acetate co-treated with Ionomycin] affects the expression of ALCAM mRNA25613284
D019284ThapsigarginThapsigargin results in increased expression of ALCAM mRNA22378314
D013853ThioacetamideThioacetamide results in increased expression of ALCAM mRNA23411599
C009495titanium dioxidetitanium dioxide results in increased expression of ALCAM mRNA23409001
D014028Tobacco Smoke PollutionTobacco Smoke Pollution results in decreased expression of ALCAM mRNA28065790
D014050TolueneToluene results in increased expression of ALCAM mRNA22967744
D019772TopotecanTopotecan results in increased expression of ALCAM mRNA25729387
D014212TretinoinTretinoin results in increased expression of ALCAM mRNA21934132
D014241TrichloroethyleneTrichloroethylene results in increased expression of ALCAM mRNA19448997
C012589trichostatin A"[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ALCAM mRNA"27188386
C012589trichostatin Atrichostatin A results in increased expression of ALCAM mRNA24935251|2627250
C015559trimellitic anhydridetrimellitic anhydride results in increased expression of ALCAM mRNA19042947
C057693troglitazonetroglitazone results in decreased expression of ALCAM mRNA28973697
D014635Valproic Acid"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ALCAM mRNA"27188386
D014635Valproic AcidValproic Acid affects the expression of ALCAM mRNA25979313
D014635Valproic AcidValproic Acid results in increased expression of ALCAM mRNA23179753|2438349
D001335Vehicle EmissionsVehicle Emissions results in decreased methylation of ALCAM gene25560391
D000069470Venlafaxine HydrochlorideVenlafaxine Hydrochloride results in increased expression of ALCAM mRNA25423262
C025643vinclozolinvinclozolin results in increased expression of ALCAM mRNA23034163|2355583
C111237vorinostat"[NOG protein co-treated with vorinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ALCAM mRNA"27188386
C111237vorinostatvorinostat results in increased expression of ALCAM mRNA26272509|2718838

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0005102signaling receptor binding-TAS7760007  
GO:0005515protein binding-IPI24945728  26146185  
GO:0042802identical protein binding-IPI26146185  
GO ID GO Term Qualifier Evidence PubMed
GO:0002250adaptive immune response-IEA-  
GO:0007155cell adhesion-ISS-  
GO:0007157heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules-IMP16352806  
GO:0007165signal transduction-TAS7760007  
GO:0008045motor neuron axon guidance-IEA-  
GO:0031290retinal ganglion cell axon guidance-ISS-  
GO:0048846axon extension involved in axon guidance-ISS-  
GO:1990138neuron projection extension-ISS-  
GO ID GO Term Qualifier Evidence PubMed
GO:0001772immunological synapse-IDA15294938  
GO:0005887integral component of plasma membrane-ISS-  
GO:0005925focal adhesion-HDA21423176  
GO:0009897external side of plasma membrane-IEA-  
GO:0030424axon-ISS-  
GO:0030425dendrite-IEA-  
GO:0031226intrinsic component of plasma membrane-IDA15294938  
GO:0042101T cell receptor complexcolocalizes_withIDA15294938  
GO:0043025neuronal cell body-IEA-  
GO:0070062extracellular exosome-HDA19056867  20458337  
KEGG ID KEGG Term
hsa04514Cell adhesion molecules (CAMs)
Reactome ID Reactome Term Evidence
R-HSA-1266738Developmental BiologyIEA
R-HSA-373760L1CAM interactionsIEA
R-HSA-422475Axon guidanceIEA

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
28811688Genetic Variation in CD166 Gene and Its Association with Bladder Cancer Risk in North Indian Population. (2017 Jul)Verma AIndian J Clin Biochem
21508219Cocaine hijacks sigma1 receptor to initiate induction of activated leukocyte cell adhesion molecule: implication for increased monocyte adhesion and migration in the CNS. (2011 Apr 20)Yao HJ Neurosci