Gene: F5

2153
FVL|PCCF|RPRGL1|THPH2
coagulation factor V
protein-coding
1q24.2
Ensembl:ENSG00000198734 MIM:612309 Vega:OTTHUMG00000034595 UniprotKB:P12259
NG_011806.1
PubMed
0   ANCO-SNPs
OD|ND
9   
NA (AD)  7.130e-2 (ND)   (Frontal_Cortex)
5.839e-1 (AD)  9.164e-1 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
GLP2R0.467
HHAT0.461
LTK0.445
LRRC20.443
OXGR10.439
SLC1A10.439
KITLG0.439
HCN40.437
TMEM200A0.436
DNAH20.435

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
BCL7C-0.273
LHPP-0.269
MPST-0.263
EFHD1-0.263
C7orf61-0.257
SLC25A48-0.249
SERPINC1-0.249
TST-0.247
S100A1-0.247
NKX2-2-0.246

Drugs/Compounds

ID Drug Name Drug Type CAS Num Status Role
DB00055Drotrecogin alfaBiotechDrug98530-76-8Approved|Investigational|WithdrawnTarget
DB05777Thrombomodulin AlfaBiotechDrug120313-91-9Approved|InvestigationalTarget
DB13149Protein S humanBiotechDrugApprovedTarget
DB13151Anti-inhibitor coagulant complexBiotechDrugApproved|InvestigationalTarget
DB13151Anti-inhibitor coagulant complexBiotechDrugApproved|InvestigationalEnzyme
DB09130CopperSmall Molecule7440-50-8Approved|InvestigationalCarrier
ID Drug Name Action PubMed
C0297902,2',3',4,4',5-hexachlorobiphenyl"2,2',3',4,4',5-hexachlorobiphenyl results in increased expression of F5 mRNA"23829299
C0630022,3-dimethoxy-1,4-naphthoquinone"2,3-dimethoxy-1,4-naphthoquinone results in decreased expression of F5 mRNA"17547211
C0164032,4-dinitrotoluene"2,4-dinitrotoluene affects the expression of F5 mRNA"21346803
C0235142,6-dinitrotoluene"2,6-dinitrotoluene results in decreased expression of F5 mRNA"20406850
C0235142,6-dinitrotoluene"2,6-dinitrotoluene affects the expression of F5 mRNA"21346803
C0065512-amino-2-methyl-1-propanol2-amino-2-methyl-1-propanol results in decreased expression of F5 mRNA25088246
C0284513,4,3',4'-tetrachlorobiphenyl"3,4,3',4'-tetrachlorobiphenyl inhibits the reaction [Dietary Fats results in increased expression of F5 mRNA]"19467301
C0095054,4'-diaminodiphenylmethane"4,4'-diaminodiphenylmethane results in increased expression of F5 mRNA"18648102
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with entinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of F5 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with mercuric bromide co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of F5 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of F5 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of F5 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of F5 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with entinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of F5 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with mercuric bromide co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of F5 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of F5 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of F5 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of F5 mRNA"27188386
D000082AcetaminophenAcetaminophen results in decreased expression of F5 mRNA29067470
D000082AcetaminophenAcetaminophen affects the expression of F5 mRNA17562736
D000082Acetaminophen[Clofibrate co-treated with Acetaminophen] affects the expression of F5 mRNA17585979
D000082AcetaminophenPPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of F5 mRNA]17585979
D020106AcrylamideAcrylamide affects the expression of F5 mRNA28959563
D016604Aflatoxin B1Aflatoxin B1 affects the expression of F5 protein20106945
D016604Aflatoxin B1Aflatoxin B1 results in decreased methylation of F5 gene27153756
D016604Aflatoxin B1Aflatoxin B1 results in decreased expression of F5 mRNA19770486
D000447AldehydesAldehydes results in decreased expression of F5 mRNA25014914
D000965AntimonyAntimony results in decreased expression of F5 mRNA17547211
D000966Antimony Potassium TartrateAntimony Potassium Tartrate results in decreased expression of F5 mRNA17547211
D018501Antirheumatic AgentsAntirheumatic Agents results in decreased expression of F5 mRNA24449571
D001151ArsenicArsenic results in decreased expression of F5 mRNA19654921
C006632arsenic trioxidearsenic trioxide results in increased expression of F5 mRNA20458559
D000069059Atorvastatin CalciumAtorvastatin Calcium results in decreased activity of F5 protein16907931
D001507BeclomethasoneBeclomethasone results in increased expression of F5 mRNA23656298
D001554BenzeneBenzene results in increased expression of F5 mRNA15120971|1512265
D001564Benzo(a)pyreneBenzo(a)pyrene results in decreased expression of F5 mRNA19770486
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of F5 mRNA27195522
D0151237,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide"7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased expression of F5 mRNA"26238291
C006780bisphenol Abisphenol A affects the expression of F5 mRNA21786754
C006780bisphenol Abisphenol A results in decreased expression of F5 mRNA21932408
C006780bisphenol Abisphenol A results in increased expression of F5 mRNA27104808
C006780bisphenol Abisphenol A results in decreased expression of F5 mRNA25181051
C006780bisphenol Abisphenol A results in increased methylation of F5 gene28505145
C018475butyraldehydebutyraldehyde results in decreased expression of F5 mRNA26079696
D002104CadmiumF5 protein binds to Cadmium23896426
D002104CadmiumCadmium results in increased expression of F5 mRNA24084258
D020245p-Chloromercuribenzoic Acid"[NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of F5 mRNA"27188386
D020245p-Chloromercuribenzoic Acidp-Chloromercuribenzoic Acid results in increased expression of F5 mRNA26272509
D002737ChloropreneChloroprene results in increased expression of F5 mRNA23125180
D002793Cholic Acids[1-Naphthylisothiocyanate co-treated with Cholic Acids] affects the expression of F5 mRNA27344345
D002857ChromiumChromium results in decreased expression of F5 mRNA17547211
C031180chrysenechrysene results in increased expression of F5 mRNA26377693
D002994Clofibrate[Clofibrate co-treated with Acetaminophen] affects the expression of F5 mRNA17585979
D002994ClofibrateClofibrate results in decreased expression of F5 mRNA23811191
D002994ClofibratePPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of F5 mRNA]17585979
D002994ClofibrateClofibrate results in decreased expression of F5 mRNA12851107
D002995Clofibric Acid[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of F5 mRNA17602206
D002996ClomipheneF5 gene polymorphism affects the susceptibility to Clomiphene19371211
C018021cobaltous chloridecobaltous chloride results in decreased expression of F5 mRNA24386269
D003276Contraceptives, Oral"F5 mutant form results in increased susceptibility to Contraceptives, Oral"9136971
D016572CyclosporineCyclosporine results in decreased expression of F5 mRNA20106945|2556210
D016572CyclosporineCyclosporine results in decreased expression of F5 mRNA19770486
C093628cyproconazolecyproconazole results in decreased expression of F5 mRNA22334560
D003703DemecolcineDemecolcine results in increased expression of F5 mRNA23649840
D003976DiazinonDiazinon results in decreased expression of F5 mRNA29108742
D003999Dichloroacetic AcidDichloroacetic Acid results in decreased expression of F5 mRNA28962523
C000944dicrotophosdicrotophos results in increased expression of F5 mRNA28302478
D004041Dietary Fats"3,4,3',4'-tetrachlorobiphenyl inhibits the reaction [Dietary Fats results in increased expression of F5 mRNA]"19467301
D004041Dietary FatsDietary Fats results in increased expression of F5 mRNA19467301
D004052Diethylnitrosamine[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of F5 mRNA17602206
D002117CalcitriolCalcitriol results in increased expression of F5 mRNA21592394
D002117Calcitriol[Testosterone co-treated with Calcitriol] results in increased expression of F5 mRNA21592394
D004128DimethylnitrosamineDimethylnitrosamine results in decreased expression of F5 mRNA17547211
D004147DioxinsDioxins affects the expression of F5 mRNA20463971
C035276eicosapentaenoic acid ethyl estereicosapentaenoic acid ethyl ester results in decreased activity of F5 protein14614217
C118739entinostatentinostat results in increased expression of F5 mRNA26272509|2718838
C118739entinostat"[NOG protein co-treated with entinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of F5 mRNA"27188386
C109476epoxiconazoleepoxiconazole results in decreased expression of F5 mRNA22334560
D004997Ethinyl EstradiolF5 gene polymorphism inhibits the reaction [[Ethinyl Estradiol co-treated with Levonorgestrel] results in decreased expression of C4BPB protein]14551147
D004997Ethinyl EstradiolEthinyl Estradiol results in decreased expression of F5 mRNA29097150
C442659ethinyl estradiol-desogestrel combinationF5 gene polymorphism promotes the reaction [ethinyl estradiol-desogestrel combination results in decreased expression of C4BPB protein]14551147
D005485FlutamideFlutamide results in decreased expression of F5 mRNA24793618
C039281furanfuran results in decreased expression of F5 mRNA25539665
C039281furanfuran results in increased methylation of F5 gene22079235
D015759Ionomycin[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of F5 mRNA25613284
C008261lead acetatelead acetate affects the expression of F5 mRNA22641619
C045463leflunomideleflunomide results in increased expression of F5 mRNA24136188
D001556LindaneLindane results in increased expression of F5 mRNA19403169
D018021Lithium ChlorideLithium Chloride results in increased expression of F5 mRNA23527032
C042720mercuric bromidemercuric bromide results in increased expression of F5 mRNA26272509
C042720mercuric bromide"[NOG protein co-treated with mercuric bromide co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of F5 mRNA"27188386
D008628MercuryMercury results in decreased expression of F5 mRNA17547211
C004925methylmercuric chloridemethylmercuric chloride results in increased expression of F5 mRNA23458150
C500085muraglitazarmuraglitazar results in decreased expression of F5 mRNA21515302
D0150581-Naphthylisothiocyanate[1-Naphthylisothiocyanate co-treated with Cholic Acids] affects the expression of F5 mRNA27344345
D009532NickelNickel results in decreased expression of F5 mRNA25583101
D009532NickelNickel results in increased expression of F5 mRNA24084258
C022838nickel chloridenickel chloride results in decreased expression of F5 mRNA17547211
D016912LevonorgestrelF5 gene polymorphism inhibits the reaction [[Ethinyl Estradiol co-treated with Levonorgestrel] results in decreased expression of C4BPB protein]14551147
D009652NorpregnenesF5 protein mutant form results in increased susceptibility to Norpregnenes7500743
C025589ochratoxin Aochratoxin A results in decreased expression of F5 mRNA29274910
C025589ochratoxin Aochratoxin A results in decreased expression of F5 mRNA19287073
C046012pentanalpentanal results in decreased expression of F5 mRNA26079696
C076994perfluorooctane sulfonic acidperfluorooctane sulfonic acid affects the expression of F5 mRNA19429403
C076994perfluorooctane sulfonic acidperfluorooctane sulfonic acid results in decreased expression of F5 mRNA20936131
C023036perfluorooctanoic acidperfluorooctanoic acid affects the expression of F5 mRNA19429403
D010634PhenobarbitalPhenobarbital affects the expression of F5 mRNA23091169
D010662Phenylmercuric Acetate"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of F5 mRNA"27188386
D010662Phenylmercuric AcetatePhenylmercuric Acetate results in increased expression of F5 mRNA26272509
C006253pirinixic acid[pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of F5 mRNA19710929
C006253pirinixic acidpirinixic acid results in decreased expression of F5 mRNA18467677|2381119
C006253pirinixic acidPPARA protein promotes the reaction [pirinixic acid results in decreased expression of F5 mRNA]18467677
C531249Poly(amidoamine)Poly(amidoamine) analog results in increased expression of F5 mRNA24813635
D011192Potassium DichromatePotassium Dichromate results in decreased expression of F5 mRNA17547211
D011374ProgesteroneProgesterone results in increased expression of F5 mRNA23012394
C045950propiconazolepropiconazole results in decreased expression of F5 mRNA21278054|2233456
C005556propionaldehydepropionaldehyde results in decreased expression of F5 mRNA26079696
C513428pyrachlostrobinpyrachlostrobin results in increased expression of F5 mRNA27029645
C041125quinaprilquinapril results in decreased activity of F5 protein16907931
C089730rosiglitazonerosiglitazone results in decreased expression of F5 mRNA21515302
C016104sodium bichromatesodium bichromate affects the expression of F5 mRNA22110744
C501413tesaglitazartesaglitazar results in decreased expression of F5 mRNA21515302
D013739Testosterone[Testosterone co-treated with Calcitriol] results in increased expression of F5 mRNA21592394
D013739TestosteroneTestosterone results in increased expression of F5 mRNA21592394
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of F5 mRNA16443690
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased expression of F5 mRNA19770486
D013755Tetradecanoylphorbol Acetate[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of F5 mRNA25613284
D014028Tobacco Smoke PollutionTobacco Smoke Pollution results in increased expression of F5 mRNA19969065
C066340tolcaponetolcapone results in increased expression of F5 mRNA24136188
D014212TretinoinF5 protein results in decreased susceptibility to Tretinoin10734661
C012589trichostatin Atrichostatin A results in increased expression of F5 mRNA24935251
D014635Valproic Acid"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of F5 mRNA"27188386
D014635Valproic AcidValproic Acid affects the expression of F5 mRNA25979313
D014635Valproic AcidValproic Acid results in increased expression of F5 mRNA23179753|2438349
D001335Vehicle EmissionsVehicle Emissions results in decreased methylation of F5 gene25560391
C025643vinclozolinvinclozolin results in increased expression of F5 mRNA23034163
D014859WarfarinF5 gene polymorphism affects the susceptibility to Warfarin19752777
D014859WarfarinF5 protein affects the susceptibility to Warfarin19752777
D015032ZincZinc deficiency results in increased expression of F5 mRNA22171008
D015032ZincZinc deficiency results in increased expression of F5 mRNA20857495

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0005507copper ion binding-IEA-  
GO:0005515protein binding-IPI2844223  6323392  9556620  
GO:0070492oligosaccharide binding-IBA21873635  
GO ID GO Term Qualifier Evidence PubMed
GO:0002576platelet degranulation-TAS-  
GO:0006888ER to Golgi vesicle-mediated transport-TAS-  
GO:0007596blood coagulation-TAS-  
GO:0008015blood circulation-IEA-  
GO:0043687post-translational protein modification-TAS-  
GO:0044267cellular protein metabolic process-TAS-  
GO:0048208COPII vesicle coating-TAS-  
GO ID GO Term Qualifier Evidence PubMed
GO:0000139Golgi membrane-IEA-  
GO:0005576extracellular region-NAS14718574  
GO:0005576extracellular region-TAS-  
GO:0005615extracellular space-IEA-  
GO:0005788endoplasmic reticulum lumen-TAS-  
GO:0005886plasma membrane-TAS-  
GO:0016020membrane-HDA19946888  
GO:0030134COPII-coated ER to Golgi transport vesicle-TAS-  
GO:0031093platelet alpha granule lumen-TAS-  
GO:0033116endoplasmic reticulum-Golgi intermediate compartment membrane-TAS-  
GO:1903561extracellular vesicle-HDA24769233  
KEGG ID KEGG Term
hsa04610Complement and coagulation cascades
Reactome ID Reactome Term Evidence
R-HSA-109582HemostasisTAS
R-HSA-114608Platelet degranulation TAS
R-HSA-140875Common Pathway of Fibrin Clot FormationTAS
R-HSA-140877Formation of Fibrin Clot (Clotting Cascade)TAS
R-HSA-199977ER to Golgi Anterograde TransportTAS
R-HSA-199991Membrane TraffickingTAS
R-HSA-204005COPII-mediated vesicle transportTAS
R-HSA-381426Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)TAS
R-HSA-392499Metabolism of proteinsTAS
R-HSA-446203Asparagine N-linked glycosylationTAS
R-HSA-5653656Vesicle-mediated transportTAS
R-HSA-5694530Cargo concentration in the ERTAS
R-HSA-597592Post-translational protein modificationTAS
R-HSA-76002Platelet activation, signaling and aggregationTAS
R-HSA-76005Response to elevated platelet cytosolic Ca2+TAS
R-HSA-8957275Post-translational protein phosphorylationTAS
R-HSA-948021Transport to the Golgi and subsequent modificationTAS

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
16353042[Associations of hemostasis factors genes with early development of ischemic heart disease and manifestation of myocardial infarction in young age]. (2005)Dankovtseva ENKardiologiia
15879922Polymorphisms associated with thrombophilia and vascular homeostasis and the timing of menarche and menopause in 728 white women. (2005 May-Jun)Tempfer CBMenopause
20148880Genetic susceptibility, smoking, obesity and risk of venous thromboembolism. (2010 Apr)Severinsen MTBr J Haematol
24911077CYP2C9, VKORC1, CYP4F2, ABCB1 and F5 variants: influence on quality of long-term anticoagulation. (2014 Apr)Nahar RPharmacol Rep
17036337Risks of human limb deficiency anomalies associated with 29 SNPs of genes involved in homocysteine metabolism, coagulation, cell-cell interactions, inflammatory response, and blood pressure regulation. (2006 Nov 15)Carmichael SLAm J Med Genet A
17683517The Mediterranean paradox for susceptibility factors in coronary heart disease extends to genetics. (2008 Jan)Lao OAnn Hum Genet
17137217Association of sixty-one non-synonymous polymorphisms in forty-one hypertension candidate genes with blood pressure variation and hypertension. (2006 Aug)Kokubo YHypertens Res
28927238Factor V Leiden is associated with increased sperm count. (2017 Nov 1)van Mens TEHum Reprod
27161691PO-04 - A new genetic risk score for predicting venous thromboembolic events in cancer patients receiving chemotherapy. (2016 Apr)Martin AJThromb Res