Gene info: ID 2171

Gene: FABP5

GENE ID: 2171

Synonyms: E-FABP|EFABP|KFABP|PA-FABP|PAFABP

Description: fatty acid binding protein 5

Gene type: protein-coding

Location: 8q21.13

dbXrefs: Ensembl:ENSG00000164687 MIM:605168 Vega:OTTHUMG00000134313 UniprotKB:Q01469

RefSeq: NG_028154.1

Retrived from: PubMed

SNPs: 0 ANCO-SNPs

Phenotype: ND|AD

# Publications: 3

Sherlock p-value : NA (AD) NA (ND) (Frontal_Cortex)

Pascal p-value : 7.114e-1 (AD) 4.640e-1 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol	Pearson Correlation Coefficient
TPST1	0.85
DYNLT1	0.82
PDPN	0.816
GADD45A	0.81
RPL22L1	0.801
S100A3	0.798
IGFLR1	0.797
CD44	0.797
PIRT	0.795
SOD2	0.792

Top 10 negatively co-expressed genes

Gene Symbol	Pearson Correlation Coefficient
OR4F5	-0.396
OR4F29	-0.36
EDN3	-0.322
NEUROD6	-0.319
F7	-0.309
ESRRG	-0.3
KCNQ4	-0.3
COL24A1	-0.298
ABCC12	-0.298
NXPH2	-0.297

ID	Drug Name	Drug Type	CAS Num	Status	Role
DB03796	Palmitic Acid	Small Molecule	57-10-3	Approved\|Experimental	Carrier

ID	Drug Name	Action	PubMed
C049325	1,2-dithiol-3-thione	"1,2-dithiol-3-thione results in increased expression of FABP5 mRNA"	19162173
C028474	1,4-bis(2-(3,5-dichloropyridyloxy))benzene	"1,4-bis(2-(3,5-dichloropyridyloxy))benzene results in decreased expression of FABP5 mRNA"	28903501
C548651	2-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester	2-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester results in increased expression of FABP5 mRNA	19933214
C511295	2,2',4,4'-tetrabromodiphenyl ether	"2,2',4,4'-tetrabromodiphenyl ether results in increased expression of FABP5 mRNA"	23146750
C511295	2,2',4,4'-tetrabromodiphenyl ether	"2,2',4,4'-tetrabromodiphenyl ether results in decreased expression of FABP5 mRNA"	27291303
C078765	2,3,5-(triglutathion-S-yl)hydroquinone	"2,3,5-(triglutathion-S-yl)hydroquinone results in decreased expression of FABP5 mRNA"	14587099
C016403	2,4-dinitrotoluene	"2,4-dinitrotoluene affects the expression of FABP5 mRNA"	21346803
C023035	3,4,5,3',4'-pentachlorobiphenyl	"3,4,5,3',4'-pentachlorobiphenyl results in increased expression of FABP5 mRNA"	20959002
C459179	4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide	"[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of FABP5 mRNA"	27188386
C459179	4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide	"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of FABP5 mRNA"	27188386
C459179	4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide	"[NOG protein co-treated with vorinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of FABP5 mRNA"	27188386
C002202	4-oxoretinoic acid	4-oxoretinoic acid results in decreased expression of FABP5 mRNA	15982314
C477187	5-(4-methylpiperazin-1-yl)-2-(2'-(3,4-dimethoxyphenyl)-5'-benzimidazolyl)benzimidazole	"5-(4-methylpiperazin-1-yl)-2-(2'-(3,4-dimethoxyphenyl)-5'-benzimidazolyl)benzimidazole results in decreased expression of FABP5 protein"	22745752
C516138	(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine	"[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of FABP5 mRNA"	27188386
C516138	(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine	"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of FABP5 mRNA"	27188386
C516138	(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine	"[NOG protein co-treated with vorinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of FABP5 mRNA"	27188386
D000082	Acetaminophen	Acetaminophen results in decreased expression of FABP5 mRNA	21420995
D000082	Acetaminophen	[Clofibrate co-treated with Acetaminophen] affects the expression of FABP5 mRNA	17585979
D000082	Acetaminophen	PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of FABP5 mRNA]	17585979
D000082	Acetaminophen	Acetaminophen results in decreased expression of FABP5 protein	16538041
D016604	Aflatoxin B1	Aflatoxin B1 results in increased expression of FABP5 mRNA	22100608
D016604	Aflatoxin B1	Aflatoxin B1 results in decreased expression of FABP5 mRNA	19770486
C103303	alitretinoin	alitretinoin results in decreased expression of FABP5 mRNA	15982314
D000643	Ammonium Chloride	Ammonium Chloride affects the expression of FABP5 mRNA	16483693
D000966	Antimony Potassium Tartrate	Antimony Potassium Tartrate results in decreased expression of FABP5 mRNA	28713220
D018501	Antirheumatic Agents	Antirheumatic Agents results in increased expression of FABP5 mRNA	24449571
C006632	arsenic trioxide	arsenic trioxide results in increased expression of FABP5 mRNA	22521957
C547126	AZM551248	AZM551248 results in decreased expression of FABP5 mRNA	22323515
C006703	benzo(b)fluoranthene	benzo(b)fluoranthene results in increased expression of FABP5 mRNA	26377693
C022921	benzo(k)fluoranthene	benzo(k)fluoranthene results in increased expression of FABP5 mRNA	26377693
D001564	Benzo(a)pyrene	Benzo(a)pyrene results in decreased expression of FABP5 mRNA	20064835
D001564	Benzo(a)pyrene	Benzo(a)pyrene results in decreased expression of FABP5 mRNA	19770486
D004958	Estradiol	Estradiol results in decreased expression of FABP5 mRNA	19484750
C023888	beta-hexachlorocyclohexane	beta-hexachlorocyclohexane results in increased expression of FABP5 mRNA	28392238
C543008	bis(4-hydroxyphenyl)sulfone	bis(4-hydroxyphenyl)sulfone results in increased expression of FABP5 mRNA	27685785
C002791	bismuth tripotassium dicitrate	bismuth tripotassium dicitrate results in increased expression of FABP5 mRNA	15912405
C006780	bisphenol A	bisphenol A results in decreased expression of FABP5 mRNA	29275510
C006780	bisphenol A	bisphenol A results in decreased expression of FABP5 protein	24909818
C006780	bisphenol A	bisphenol A results in increased expression of FABP5 protein	24909818
C013418	bromfenacoum	bromfenacoum results in decreased expression of FABP5 protein	28903499
D002065	Buspirone	Buspirone results in decreased expression of FABP5 mRNA	24136188
C018475	butyraldehyde	butyraldehyde results in increased expression of FABP5 mRNA	26079696
D002104	Cadmium	Cadmium results in increased expression of FABP5 mRNA	17066326
D019256	Cadmium Chloride	Cadmium Chloride results in increased expression of FABP5 mRNA	17066326
D002211	Capsaicin	Capsaicin results in decreased expression of FABP5 mRNA	18533110
D002713	Chlorine	[Ozone co-treated with Chlorine] results in decreased expression of FABP5 mRNA	18636392
C100187	chloropicrin	chloropicrin results in increased expression of FABP5 mRNA	26352163\|2847649
D002922	Ciguatoxins	Ciguatoxins affects the expression of FABP5 mRNA	18353800
D002994	Clofibrate	[Clofibrate co-treated with Acetaminophen] affects the expression of FABP5 mRNA	17585979
D002994	Clofibrate	PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of FABP5 mRNA]	17585979
D002995	Clofibric Acid	Clofibric Acid affects the expression of FABP5 mRNA	17602206
C018021	cobaltous chloride	cobaltous chloride results in decreased expression of FABP5 mRNA	19376846
C018021	cobaltous chloride	cobaltous chloride results in increased expression of FABP5 mRNA	24386269
C018021	cobaltous chloride	cobaltous chloride results in increased expression of FABP5 protein	24386269
D003300	Copper	[ATP7A gene mutant form results in increased abundance of Copper] which results in decreased expression of FABP5 mRNA	15467011
D003300	Copper	Copper results in decreased expression of FABP5 mRNA	17205981
D019327	Copper Sulfate	Copper Sulfate results in decreased expression of FABP5 mRNA	19549813
D003375	Coumestrol	[Coumestrol co-treated with ESR1 protein] results in increased expression of FABP5 mRNA	18310284
D003375	Coumestrol	ESR2 protein affects the reaction [[Coumestrol co-treated with ESR1 protein] results in increased expression of FABP5 mRNA]	18310284
C014347	decitabine	[decitabine affects the methylation of FABP5 promoter] which affects the expression of FABP5 protein	18636205\|1863620
D013759	Dronabinol	Dronabinol results in increased expression of FABP5 mRNA	16616335
D003907	Dexamethasone	Dexamethasone results in increased expression of FABP5 mRNA	25047013
D003907	Dexamethasone	[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin] results in increased expression of FABP5 mRNA	28628672
D003907	Dexamethasone	[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of FABP5 mRNA	23428407
D003993	Dibutyl Phthalate	Dibutyl Phthalate results in decreased expression of FABP5 mRNA	17379624
D003999	Dichloroacetic Acid	Dichloroacetic Acid results in decreased expression of FABP5 mRNA	28962523
D002945	Cisplatin	Cisplatin results in decreased expression of FABP5 mRNA	22023808
D004008	Diclofenac	Diclofenac results in increased expression of FABP5 mRNA	26934552
D004040	Dietary Carbohydrates	Dietary Carbohydrates results in increased expression of FABP5 mRNA	17490981
D004041	Dietary Fats	[Dietary Fats co-treated with Quercetin] affects the expression of FABP5 mRNA	25047408
D004051	Diethylhexyl Phthalate	Diethylhexyl Phthalate results in increased expression of FABP5 mRNA	28412506
D004051	Diethylhexyl Phthalate	Diethylhexyl Phthalate results in decreased expression of FABP5 mRNA	28085963
D004051	Diethylhexyl Phthalate	Diethylhexyl Phthalate results in increased expression of FABP5 mRNA	19850644
D004051	Diethylhexyl Phthalate	PPARA protein promotes the reaction [Diethylhexyl Phthalate results in increased expression of FABP5 mRNA]	19850644
D004052	Diethylnitrosamine	Diethylnitrosamine results in increased expression of FABP5 mRNA	24535843
D004052	Diethylnitrosamine	[Diethylnitrosamine co-treated with Thioacetamide] results in increased expression of FABP5 mRNA	28943392
D004052	Diethylnitrosamine	Diethylnitrosamine results in increased expression of FABP5 mRNA	19638242
D004054	Diethylstilbestrol	Diethylstilbestrol results in increased expression of FABP5 mRNA	15171707
D004237	Diuron	Diuron results in increased expression of FABP5 mRNA	21551480
D004281	Docosahexaenoic Acids	Docosahexaenoic Acids results in decreased expression of FABP5 mRNA	16623957
D004317	Doxorubicin	Doxorubicin results in decreased expression of FABP5 mRNA	21040762
D004317	Doxorubicin	[[MT1 protein co-treated with MT2 protein] affects the susceptibility to Doxorubicin] which affects the expression of FABP5 mRNA	21040762
D004642	Emodin	Emodin results in decreased expression of FABP5 mRNA	15612046
D004791	Enzyme Inhibitors	[Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation of FABP5 protein	23301498
D000431	Ethanol	Ethanol results in decreased expression of FABP5 mRNA	19167417
D000431	Ethanol	Ethanol results in decreased expression of FABP5 mRNA	17920746
D004997	Ethinyl Estradiol	Ethinyl Estradiol results in increased expression of FABP5 mRNA	17942748
D004997	Ethinyl Estradiol	[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of FABP5 mRNA	17942748
D004997	Ethinyl Estradiol	Ethinyl Estradiol affects the expression of FABP5 mRNA	17351261
D004997	Ethinyl Estradiol	Ethinyl Estradiol results in increased expression of FABP5 mRNA	15576828\|1617478
D005020	Ethyl Methanesulfonate	Ethyl Methanesulfonate results in decreased expression of FABP5 mRNA	23649840
D005411	Flame Retardants	Flame Retardants results in decreased expression of FABP5 protein	18550172
D005411	Flame Retardants	Flame Retardants results in increased expression of FABP5 protein	18550172
D005485	Flutamide	Flutamide results in increased expression of FABP5 mRNA	24136188
D004397	Fonofos	Fonofos results in increased methylation of FABP5 promoter	22847954
C039281	furan	furan results in increased expression of FABP5 mRNA	20124500\|2553966
C546771	gardiquimod	gardiquimod results in increased expression of FABP5 mRNA	28003376
C546771	gardiquimod	Protein Kinase Inhibitors inhibits the reaction [gardiquimod results in increased expression of FABP5 mRNA]	28003376
D005897	Glafenine	Glafenine results in increased expression of FABP5 mRNA	24136188
D006861	Hydrogen Peroxide	Hydrogen Peroxide affects the expression of FABP5 mRNA	21179406
C492448	ICG 001	ICG 001 results in decreased expression of FABP5 mRNA	26191083
D007213	Indomethacin	[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin] results in increased expression of FABP5 mRNA	28628672
D015759	Ionomycin	[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of FABP5 mRNA	25613284
D015056	1-Methyl-3-isobutylxanthine	[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin] results in increased expression of FABP5 mRNA	28628672
D015056	1-Methyl-3-isobutylxanthine	[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of FABP5 mRNA	23428407
D007545	Isoproterenol	Isoproterenol results in increased expression of FABP5 mRNA	21335049
C561695	(+)-JQ1 compound	(+)-JQ1 compound results in decreased expression of FABP5 mRNA	26752646
C410337	K 7174	K 7174 results in decreased expression of FABP5 mRNA	24086573
D007854	Lead	FABP5 protein binds to Lead	23896426
D007854	Lead	Lead affects the expression of FABP5 mRNA	28903495
D008558	Melphalan	Melphalan results in increased expression of FABP5 mRNA	22363485
D008628	Mercury	Mercury results in increased expression of FABP5 mRNA	12730625
C004925	methylmercuric chloride	methylmercuric chloride results in increased expression of FABP5 mRNA	28001369
D008741	Methyl Methanesulfonate	Methyl Methanesulfonate results in decreased expression of FABP5 mRNA	23649840
D018817	N-Methyl-3,4-methylenedioxyamphetamine	"N-Methyl-3,4-methylenedioxyamphetamine results in increased expression of FABP5 mRNA"	20188158
C063855	microcystin RR	microcystin RR results in decreased expression of FABP5 protein	19111056
C047806	monomethylpropion	monomethylpropion results in increased expression of FABP5 mRNA	22303338
D009151	Mustard Gas	Mustard Gas results in decreased expression of FABP5 mRNA	25102026
D037742	Nanotubes, Carbon	"Nanotubes, Carbon results in decreased expression of FABP5 mRNA"	24389112
D037742	Nanotubes, Carbon	"Nanotubes, Carbon affects the expression of FABP5 mRNA"	25554681
D037742	Nanotubes, Carbon	"Nanotubes, Carbon analog results in decreased expression of FABP5 mRNA"	25620056
D037742	Nanotubes, Carbon	"Nanotubes, Carbon analog results in increased expression of FABP5 mRNA"	25554681
D037742	Nanotubes, Carbon	"Nanotubes, Carbon results in decreased expression of FABP5 mRNA"	25620056
C017096	n-butoxyethanol	n-butoxyethanol results in increased expression of FABP5 mRNA	19812364
C051752	nefazodone	nefazodone results in decreased expression of FABP5 mRNA	24136188
C028007	nickel monoxide	nickel monoxide results in increased expression of FABP5 mRNA	19167457
C029938	nickel sulfate	nickel sulfate results in decreased expression of FABP5 mRNA	18651567
C029938	nickel sulfate	nickel sulfate results in increased expression of FABP5 mRNA	16780908
C012655	nimesulide	nimesulide results in decreased expression of FABP5 mRNA	24136188
C025589	ochratoxin A	ochratoxin A results in decreased expression of FABP5 mRNA	16251485
D000069463	Olive Oil	Olive Oil analog affects the expression of FABP5 mRNA	17349074
D015525	Fatty Acids, Omega-3	"Fatty Acids, Omega-3 deficiency results in increased expression of FABP5 mRNA"	29175182
D010100	Oxygen	Oxygen results in increased expression of FABP5 mRNA	22911455
D010126	Ozone	[Ozone co-treated with Chlorine] results in decreased expression of FABP5 mRNA	18636392
D010269	Paraquat	Paraquat results in increased expression of FABP5 mRNA	21371552
D010278	Parathion	Parathion results in increased methylation of FABP5 promoter	22847954
C086401	pentabromodiphenyl ether	pentabromodiphenyl ether results in decreased expression of FABP5 protein	18550172
C086401	pentabromodiphenyl ether	pentabromodiphenyl ether results in increased expression of FABP5 protein	18550172
C076994	perfluorooctane sulfonic acid	perfluorooctane sulfonic acid results in decreased expression of FABP5 protein	26178269
C076994	perfluorooctane sulfonic acid	perfluorooctane sulfonic acid affects the expression of FABP5 mRNA	19162173
C023036	perfluorooctanoic acid	perfluorooctanoic acid results in increased expression of FABP5 mRNA	19162173
D010615	Phenacetin	Phenacetin results in increased expression of FABP5 mRNA	17698508
D010634	Phenobarbital	Phenobarbital results in decreased expression of FABP5 mRNA	23091169
D010634	Phenobarbital	Phenobarbital affects the expression of FABP5 mRNA	19162173
C030299	phenylhydrazine	phenylhydrazine results in increased expression of FABP5 mRNA	17698508
D010882	Piperonyl Butoxide	Piperonyl Butoxide results in decreased expression of FABP5 mRNA	22484513
C006253	pirinixic acid	pirinixic acid results in decreased expression of FABP5 mRNA	16985257\|1844570
C006253	pirinixic acid	pirinixic acid results in increased expression of FABP5 mRNA	18301758
D017035	Pravastatin	Pravastatin results in increased expression of FABP5 mRNA	27225895
D017035	Pravastatin	Pravastatin results in increased expression of FABP5 mRNA	27225895
D011285	Pregnenolone Carbonitrile	Pregnenolone Carbonitrile results in increased expression of FABP5 mRNA	28903501
D011285	Pregnenolone Carbonitrile	Pregnenolone Carbonitrile results in decreased expression of FABP5 mRNA	19162173
D011374	Progesterone	Progesterone results in decreased expression of FABP5 mRNA	19693291
C045950	propiconazole	propiconazole results in decreased expression of FABP5 mRNA	16730040\|2127805
D011441	Propylthiouracil	Propylthiouracil results in increased expression of FABP5 mRNA	24780913
D047428	Protein Kinase Inhibitors	Protein Kinase Inhibitors inhibits the reaction [gardiquimod results in increased expression of FABP5 mRNA]	28003376
D011794	Quercetin	[Dietary Fats co-treated with Quercetin] affects the expression of FABP5 mRNA	25047408
D015125	Oxyquinoline	Oxyquinoline results in decreased expression of FABP5 mRNA	15612046
D015474	Isotretinoin	Isotretinoin results in decreased expression of FABP5 mRNA	15982314
C089730	rosiglitazone	rosiglitazone affects the expression of FABP5 protein	19556978
C089730	rosiglitazone	rosiglitazone affects the expression of FABP5 protein	21347706
C089730	rosiglitazone	rosiglitazone results in increased expression of FABP5 mRNA	21172411
C541923	sandostatinLAR	sandostatinLAR results in increased expression of FABP5 mRNA	17210224
D012524	Sarin	Sarin results in decreased expression of FABP5 protein	28973502
D012822	Silicon Dioxide	Silicon Dioxide analog results in increased expression of FABP5 mRNA	25895662
D012906	Smoke	Smoke results in decreased expression of FABP5 mRNA	26109882
C009277	sodium arsenate	sodium arsenate results in decreased expression of FABP5 mRNA	12727804
C017947	sodium arsenite	sodium arsenite results in decreased expression of FABP5 mRNA	28713220
C017947	sodium arsenite	sodium arsenite results in decreased expression of FABP5 protein	19294697
C017947	sodium arsenite	sodium arsenite results in increased expression of FABP5 mRNA	28595984
C016104	sodium bichromate	sodium bichromate results in increased expression of FABP5 mRNA	22561333
D012999	Soman	Soman results in increased expression of FABP5 mRNA	19281266
D053260	Soot	Soot results in increased expression of FABP5 mRNA	26551751
C075117	squalestatin 1	squalestatin 1 results in increased expression of FABP5 mRNA	27225895
C075117	squalestatin 1	squalestatin 1 results in increased expression of FABP5 mRNA	27225895
C041711	St. Thomas' Hospital cardioplegic solution	St. Thomas' Hospital cardioplegic solution results in decreased expression of FABP5 mRNA	16214533
D014284	Triiodothyronine	Triiodothyronine results in increased expression of FABP5 mRNA	15953391
C012568	terbufos	terbufos results in increased methylation of FABP5 promoter	22847954
D013739	Testosterone	Testosterone results in decreased expression of FABP5 mRNA	19693291
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin affects the expression of FABP5 mRNA	16611356\|2637764
D013749	Tetrachlorodibenzodioxin	[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of FABP5 mRNA	17942748
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin results in decreased expression of FABP5 mRNA	28238261
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin results in increased expression of FABP5 mRNA	15800033\|1696003
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin results in decreased expression of FABP5 mRNA	11752688
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin results in increased expression of FABP5 mRNA	16054898\|1696003
D013755	Tetradecanoylphorbol Acetate	[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of FABP5 mRNA	25613284
D013792	Thalidomide	Thalidomide results in decreased expression of FABP5 mRNA	26217789
D013853	Thioacetamide	[Diethylnitrosamine co-treated with Thioacetamide] results in increased expression of FABP5 mRNA	28943392
D014028	Tobacco Smoke Pollution	Tobacco Smoke Pollution affects the expression of FABP5 mRNA	20133372
D014028	Tobacco Smoke Pollution	Tobacco Smoke Pollution results in increased expression of FABP5 protein	27818348
D014050	Toluene	Toluene results in decreased expression of FABP5 mRNA	22967744
D014212	Tretinoin	Tretinoin metabolite results in increased expression of FABP5 mRNA	15982314
D014212	Tretinoin	Tretinoin results in decreased expression of FABP5 mRNA	15982314\|2372400
C011559	tributyltin	tributyltin results in increased expression of FABP5 mRNA	23428407
C012589	trichostatin A	"[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of FABP5 mRNA"	27188386
C012589	trichostatin A	trichostatin A results in increased expression of FABP5 mRNA	24935251\|2627250
C005445	triphenyl phosphate	triphenyl phosphate results in increased expression of FABP5 mRNA	28934090
C016805	tris(1,3-dichloro-2-propyl)phosphate	"tris(1,3-dichloro-2-propyl)phosphate results in decreased expression of FABP5 mRNA"	26179874
C057693	troglitazone	troglitazone results in increased expression of FABP5 mRNA	12732648\|2897369
D014520	Urethane	Urethane results in decreased expression of FABP5 mRNA	28818685
C406224	valdecoxib	valdecoxib results in decreased expression of FABP5 mRNA	24136188
D014635	Valproic Acid	"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of FABP5 mRNA"	27188386
D014635	Valproic Acid	Valproic Acid results in decreased methylation of FABP5 gene	29154799
D014635	Valproic Acid	Valproic Acid results in increased expression of FABP5 mRNA	23179753\|2438349
D014638	Vanadates	Vanadates results in decreased expression of FABP5 mRNA	22714537
D014800	Vitallium	Vitallium analog results in decreased expression of FABP5 mRNA	23825117
D002762	Cholecalciferol	Cholecalciferol results in decreased expression of FABP5 mRNA	16508948
C111237	vorinostat	"[NOG protein co-treated with vorinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of FABP5 mRNA"	27188386
D015032	Zinc	Zinc results in decreased expression of FABP5 mRNA	15226459
D019287	Zinc Sulfate	Zinc Sulfate results in decreased expression of FABP5 mRNA	15226459

GO/Pathway

GO ID	GO Term	Qualifier	Evidence	PubMed
GO:0001972	retinoic acid binding	-	IEA	-
GO:0005504	fatty acid binding	-	IDA	8092987
GO:0005515	protein binding	-	IPI	12839573
GO:0008289	lipid binding	-	TAS	1512466
GO:0042802	identical protein binding	-	IDA	24531463

GO ID	GO Term	Qualifier	Evidence	PubMed
GO:0006006	glucose metabolic process	-	IEA	-
GO:0006629	lipid metabolic process	-	TAS	8092987
GO:0006656	phosphatidylcholine biosynthetic process	-	IEA	-
GO:0008544	epidermis development	-	TAS	1512466
GO:0010829	negative regulation of glucose transmembrane transport	-	IEA	-
GO:0019433	triglyceride catabolic process	-	TAS	-
GO:0031392	regulation of prostaglandin biosynthetic process	-	IEA	-
GO:0035360	positive regulation of peroxisome proliferator activated receptor signaling pathway	-	IEA	-
GO:0042593	glucose homeostasis	-	IEA	-
GO:0043312	neutrophil degranulation	-	TAS	-
GO:0051930	regulation of sensory perception of pain	-	IEA	-
GO:0099178	regulation of retrograde trans-synaptic signaling by endocanabinoid	-	ISS	-

GO ID	GO Term	Qualifier	Evidence	PubMed
GO:0005576	extracellular region	-	TAS	-
GO:0005634	nucleus	-	IDA	24692551
GO:0005654	nucleoplasm	-	TAS	-
GO:0005737	cytoplasm	-	IDA	8092987
GO:0005737	cytoplasm	-	TAS	16130169
GO:0005829	cytosol	-	TAS	-
GO:0005886	plasma membrane	-	TAS	-
GO:0014069	postsynaptic density	-	ISS	-
GO:0030667	secretory granule membrane	-	TAS	-
GO:0035578	azurophil granule lumen	-	TAS	-
GO:0045202	synapse	-	ISS	-
GO:0070062	extracellular exosome	-	HDA	20458337 23533145

KEGG ID	KEGG Term
hsa03320	PPAR signaling pathway

Reactome ID	Reactome Term	Evidence
R-HSA-1430728	Metabolism	TAS
R-HSA-162582	Signal Transduction	TAS
R-HSA-163560	Triglyceride catabolism	TAS
R-HSA-168249	Innate Immune System	TAS
R-HSA-168256	Immune System	TAS
R-HSA-5362517	Signaling by Retinoic Acid	TAS
R-HSA-556833	Metabolism of lipids	TAS
R-HSA-6798695	Neutrophil degranulation	TAS
R-HSA-8979227	Triglyceride metabolism	TAS
R-HSA-9006931	Signaling by Nuclear Receptors	TAS

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID	Title (Year)	Author	Journal
28542209	Cigarette smoke inhibits LPS-induced FABP5 expression by preventing c-Jun binding to the FABP5 promoter. (2017)	Rao D	PLoS One
29367955	Pharmacological Inhibition of Brain Fatty Acid Binding Protein Reduces Ethanol Consumption in Mice. (2017)	Figueiredo A	J Reward Defic Syndr Addict Sci
23349676	Cigarette smoke decreases airway epithelial FABP5 expression and promotes Pseudomonas aeruginosa infection. (2013)	Gally F	PLoS One