Gene: FASN

2194
FAS|OA-519|SDR27X1
fatty acid synthase
protein-coding
17q25.3
Ensembl:ENSG00000169710 MIM:600212 Vega:OTTHUMG00000178527 UniprotKB:P49327
NC_000017.11
PubMed
ND
3   
NA (AD)  NA (ND)   (Frontal_Cortex)
2.098e-1 (AD)  1.928e-1 (ND)

DNA Methylation

Probe Locus(GRCh37) Gene Region p-val Trait PubMed ID
cg05953751chr17:80054291FASNGene body5.398e-5Alcohol use disorders26763658
cg25068915chr17:80052907FASNGene body2.270e-4Alcohol use disorders26763658
cg14797580chr17:80053635FASNGene body3.325e-4Alcohol use disorders26763658

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
SREBF20.948
AP3D10.927
CLUH0.918
MEGF80.917
ABCA30.916
CLCN60.911
DENND1A0.909
GRIK50.909
TAOK20.908
MARK40.907

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
OR4F5-0.625
OR4F29-0.571
TFPI2-0.432
KCNJ15-0.426
IL18RAP-0.425
CST7-0.421
CXCR2-0.418
SLAMF6-0.411
CEACAM4-0.409
CD48-0.408

Drugs/Compounds

ID Drug Name Drug Type CAS Num Status Role
DB01034CeruleninSmall Molecule17397-89-6ApprovedTarget
DB01083OrlistatSmall Molecule96829-58-2Approved|InvestigationalTarget
ID Drug Name Action PubMed
C0264861,2,5,6-dibenzanthracene"[Benzo(a)pyrene co-treated with 1,2,5,6-dibenzanthracene] affects the expression of FASN mRNA"17690111
C0493251,2-dithiol-3-thione"1,2-dithiol-3-thione results in decreased expression of FASN mRNA"15302862
C0493251,2-dithiol-3-thione"1,2-dithiol-3-thione results in increased expression of FASN mRNA"19162173
C0317631,3-butadiene"1,3-butadiene results in decreased expression of FASN mRNA"21147608
C0334891,3-dichloro-2-propanol"1,3-dichloro-2-propanol results in increased expression of FASN protein"24333398
C0184061-(3-trifluoromethylphenyl)piperazine1-(3-trifluoromethylphenyl)piperazine results in increased expression of FASN mRNA26821219
C0284741,4-bis(2-(3,5-dichloropyridyloxy))benzene"1,4-bis(2-(3,5-dichloropyridyloxy))benzene results in increased expression of FASN mRNA"27180240
C0284741,4-bis(2-(3,5-dichloropyridyloxy))benzene"NR1I3 protein affects the reaction [1,4-bis(2-(3,5-dichloropyridyloxy))benzene results in increased expression of FASN mRNA]"27180240
C4901661-(4-methoxyphenyl)piperazine1-(4-methoxyphenyl)piperazine results in increased expression of FASN mRNA26821219
C0388902,3,4,7,8-pentachlorodibenzofuran"2,3,4,7,8-pentachlorodibenzofuran results in decreased expression of FASN mRNA"21724226
C0142112,3,7,8-tetrachlorodibenzofuran"2,3,7,8-tetrachlorodibenzofuran results in decreased expression of FASN mRNA"21724226
C0140242,4,5,2',4',5'-hexachlorobiphenyl"2,4,5,2',4',5'-hexachlorobiphenyl promotes the reaction [Dietary Fats results in increased expression of FASN mRNA]"23618531
C0140242,4,5,2',4',5'-hexachlorobiphenyl"2,4,5,2',4',5'-hexachlorobiphenyl promotes the reaction [Tetrachlorodibenzodioxin results in decreased expression of FASN mRNA]"21851831
C0140242,4,5,2',4',5'-hexachlorobiphenyl"2,4,5,2',4',5'-hexachlorobiphenyl results in decreased expression of FASN mRNA"20005886|2185183
C0140242,4,5,2',4',5'-hexachlorobiphenyl"2,4,5,2',4',5'-hexachlorobiphenyl results in increased expression of FASN mRNA"23618531
C0140242,4,5,2',4',5'-hexachlorobiphenyl"Dietary Fats promotes the reaction [2,4,5,2',4',5'-hexachlorobiphenyl results in increased expression of FASN mRNA]"23618531
C0140242,4,5,2',4',5'-hexachlorobiphenyl"[Tetrachlorodibenzodioxin co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Diethylhexyl Phthalate co-treated with bisphenol A] results in decreased expression of FASN mRNA"28433925
C0140242,4,5,2',4',5'-hexachlorobiphenyl"Tetrachlorodibenzodioxin promotes the reaction [2,4,5,2',4',5'-hexachlorobiphenyl results in decreased expression of FASN mRNA]"21851831
C0164032,4-dinitrotoluene"2,4-dinitrotoluene affects the expression of FASN mRNA"21346803
C0112692,5-hexanedione"2,5-hexanedione results in decreased expression of FASN protein"19033394
C0235142,6-dinitrotoluene"2,6-dinitrotoluene results in decreased expression of FASN mRNA"20406850
C0235142,6-dinitrotoluene"2,6-dinitrotoluene affects the expression of FASN mRNA"21346803
C5724913-(2-hydroxy-4-(2-methylnonan-2-yl)phenyl)cyclohexan-1-ol3-(2-hydroxy-4-(2-methylnonan-2-yl)phenyl)cyclohexan-1-ol results in increased expression of FASN protein26194647
C0230353,4,5,3',4'-pentachlorobiphenyl"3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of FASN mRNA"28163111
C0230353,4,5,3',4'-pentachlorobiphenyl"[Methionine deficiency co-treated with Choline deficiency co-treated with 3,4,5,3',4'-pentachlorobiphenyl] results in decreased expression of FASN mRNA"28163111
C0230353,4,5,3',4'-pentachlorobiphenyl"3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of FASN mRNA"19692669|2095900
C5815404-(2-(3,5-dimethoxyphenyl)vinyl)pyridine"4-(2-(3,5-dimethoxyphenyl)vinyl)pyridine results in decreased expression of FASN protein"23035943
C5241064-(4-(3-adamantan-1-ylureido)cyclohexyloxy)benzoic acid4-(4-(3-adamantan-1-ylureido)cyclohexyloxy)benzoic acid results in decreased expression of FASN mRNA23305094
C5241064-(4-(3-adamantan-1-ylureido)cyclohexyloxy)benzoic acid4-(4-(3-adamantan-1-ylureido)cyclohexyloxy)benzoic acid results in decreased expression of FASN protein23305094
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of FASN mRNA"27188386
C0974704'-methoxychalcone4'-methoxychalcone analog inhibits the reaction [TNF protein results in decreased expression of FASN mRNA]28528971
C0974704'-methoxychalcone4'-methoxychalcone analog results in increased expression of FASN mRNA28528971
C4067344-methylene-2-octyl-5-oxofuran-3-carboxylic acid4-methylene-2-octyl-5-oxofuran-3-carboxylic acid binds to and results in decreased activity of FASN protein17847090
C4067344-methylene-2-octyl-5-oxofuran-3-carboxylic acid[4-methylene-2-octyl-5-oxofuran-3-carboxylic acid co-treated with Cisplatin] results in decreased expression of FASN protein21442130
C4067344-methylene-2-octyl-5-oxofuran-3-carboxylic acid4-methylene-2-octyl-5-oxofuran-3-carboxylic acid results in decreased activity of FASN protein21442130
C4067344-methylene-2-octyl-5-oxofuran-3-carboxylic acid[4-methylene-2-octyl-5-oxofuran-3-carboxylic acid results in decreased activity of FASN protein] which results in increased susceptibility to Cisplatin21442130
C4067344-methylene-2-octyl-5-oxofuran-3-carboxylic acid4-methylene-2-octyl-5-oxofuran-3-carboxylic acid results in decreased activity of FASN protein14736702|1570798
C4067344-methylene-2-octyl-5-oxofuran-3-carboxylic acid4-methylene-2-octyl-5-oxofuran-3-carboxylic acid results in decreased expression of FASN mRNA15707987
C4067344-methylene-2-octyl-5-oxofuran-3-carboxylic acid4-methylene-2-octyl-5-oxofuran-3-carboxylic acid results in decreased activity of FASN protein17283163
C0165834-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of FASN protein18413838
C0415944-nonylphenol4-nonylphenol results in increased expression of FASN mRNA24388992
C0022024-oxoretinoic acid4-oxoretinoic acid results in increased expression of FASN mRNA15982314
C1052604-tert-octylphenol4-tert-octylphenol results in decreased expression of FASN mRNA26164745
C1052604-tert-octylphenol4-tert-octylphenol results in decreased expression of FASN protein26164745
C5732335,7-dihydroxy-2-methyl-8-(4-(3-hydroxy-1-methyl)-piperidinyl)-4H-1-benzopyran-4-one"5,7-dihydroxy-2-methyl-8-(4-(3-hydroxy-1-methyl)-piperidinyl)-4H-1-benzopyran-4-one affects the expression of FASN mRNA"24646949
C5732335,7-dihydroxy-2-methyl-8-(4-(3-hydroxy-1-methyl)-piperidinyl)-4H-1-benzopyran-4-one"5,7-dihydroxy-2-methyl-8-(4-(3-hydroxy-1-methyl)-piperidinyl)-4H-1-benzopyran-4-one affects the expression of FASN protein"24646949
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of FASN mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine inhibits the reaction [Nicotine results in decreased activity of FASN protein]"17635921
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine inhibits the reaction [Peroxynitrous Acid results in decreased activity of FASN protein]"17635921
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine inhibits the reaction [resveratrol metabolite inhibits the reaction [TO-901317 results in increased expression of FASN mRNA]]"24633463
C099958acanthoic acidacanthoic acid inhibits the reaction [Ethanol results in increased expression of FASN mRNA]28964808
C099958acanthoic acidacanthoic acid inhibits the reaction [Ethanol results in increased expression of FASN protein]28964808
D020909AcarboseAcarbose results in decreased expression of FASN mRNA8101498
D020909AcarboseAcarbose results in decreased expression of FASN protein8101498
D000082AcetaminophenAcetaminophen results in decreased expression of FASN mRNA29067470
D000082AcetaminophenAcetaminophen results in increased expression of FASN mRNA21420995
D000082AcetaminophenAcetaminophen affects the expression of FASN mRNA17562736
D000082AcetaminophenAcetaminophen results in decreased expression of FASN mRNA15084756|1752207
D020106AcrylamideAcrylamide results in decreased expression of FASN mRNA28959563
D000255Adenosine TriphosphateFASN protein promotes the reaction [rosiglitazone promotes the reaction [PPARG protein results in decreased abundance of Adenosine Triphosphate]]26670611
D000255Adenosine TriphosphateFASN protein results in decreased abundance of Adenosine Triphosphate26670611
D000255Adenosine TriphosphateProtein Kinase Inhibitors inhibits the reaction [FASN protein results in decreased abundance of Adenosine Triphosphate]26670611
C560978aegeline[Caffeine co-treated with coclaurine co-treated with aegeline co-treated with higenamine co-treated with Yohimbine co-treated with Hydrolyzable Tannins] results in decreased expression of FASN mRNA28843594
D016604Aflatoxin B1Aflatoxin B1 results in decreased expression of FASN mRNA23385219
D016604Aflatoxin B1[sulforafan co-treated with Aflatoxin B1] affects the expression of FASN mRNA25450479
C031143AICA ribonucleotide[AICA ribonucleotide results in increased activity of PRKAA2 protein] which results in decreased activity of FASN protein17635921
D000438AlcoholsAlcohols results in increased expression of FASN protein28803762
D000438AlcoholsApigenin inhibits the reaction [Alcohols results in increased expression of FASN protein]28803762
D000438AlcoholsGlutathione inhibits the reaction [Alcohols results in increased expression of FASN protein]28803762
C103303alitretinoinalitretinoin results in decreased expression of FASN mRNA15982314
D000493AllopurinolAllopurinol inhibits the reaction [Glucose results in increased expression of FASN protein]23647015
D000493AllopurinolAllopurinol inhibits the reaction [Glucose results in increased expression of FASN protein]23647015
D000493AllopurinolAllopurinol inhibits the reaction [Streptozocin results in increased expression of FASN mRNA]23647015
D000493AllopurinolAllopurinol inhibits the reaction [Streptozocin results in increased expression of FASN protein]23647015
C038491allyl sulfideallyl sulfide results in decreased expression of FASN protein22138249
D013196DihydrotestosteroneDihydrotestosterone results in increased expression of FASN mRNA16990341
D017962alpha-Linolenic Acidalpha-Linolenic Acid results in decreased expression of FASN mRNA14563831
D000638AmiodaroneAmiodarone affects the expression of FASN mRNA29248575
D000638AmiodaroneAmiodarone results in increased expression of FASN mRNA24489787
C030419andrographolideandrographolide inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of FASN mRNA]27475717
C030419andrographolideandrographolide inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of FASN protein]27475717
D047310ApigeninApigenin inhibits the reaction [Alcohols results in increased expression of FASN protein]28803762
C004984apocarotenalapocarotenal results in decreased expression of FASN mRNA17034753
D016718Arachidonic AcidArachidonic Acid results in decreased expression of FASN mRNA19159447
C026987aroclor 1260[Dietary Fats co-treated with aroclor 1260] results in decreased expression of FASN mRNA24998970
D001151ArsenicArsenic affects the methylation of FASN gene25304211
C006632arsenic trioxidearsenic trioxide results in increased expression of FASN protein25419056
C512174atheronal-Aatheronal-A inhibits the reaction [TO-901317 results in increased expression of FASN mRNA]27703007
D000069059Atorvastatin CalciumAtorvastatin Calcium results in increased expression of FASN mRNA11728391
D000069059Atorvastatin CalciumAtorvastatin Calcium results in increased expression of FASN mRNA12056585
D000069059Atorvastatin CalciumMevalonic Acid inhibits the reaction [Atorvastatin Calcium results in increased expression of FASN mRNA]12056585
D001280AtrazineAtrazine results in increased expression of FASN mRNA22378314
C006680baicaleinbaicalein results in decreased expression of FASN protein24560969
C028559bathocuproine sulfonatebathocuproine sulfonate inhibits the reaction [copper histidine results in increased expression of FASN mRNA]24170205
D001554BenzeneBenzene results in increased expression of FASN mRNA19162166
D001554BenzeneBenzene results in decreased expression of FASN mRNA15878777
C006703benzo(b)fluoranthene[Benzo(a)pyrene co-treated with benzo(b)fluoranthene] affects the expression of FASN mRNA17690111
D001564Benzo(a)pyrene"[Benzo(a)pyrene co-treated with 1,2,5,6-dibenzanthracene] affects the expression of FASN mRNA"17690111
D001564Benzo(a)pyrene[Benzo(a)pyrene co-treated with benzo(b)fluoranthene] affects the expression of FASN mRNA17690111
D001564Benzo(a)pyreneBenzo(a)pyrene results in decreased expression of FASN mRNA16269432
D001564Benzo(a)pyreneAHR protein affects the reaction [Benzo(a)pyrene affects the expression of FASN mRNA]22228805
D001564Benzo(a)pyreneBenzo(a)pyrene affects the reaction [GCLM gene mutant form results in decreased expression of FASN mRNA]24291350
D001564Benzo(a)pyreneBenzo(a)pyrene results in decreased expression of FASN mRNA19770486
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of FASN mRNA21569818|2196490
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of FASN mRNA26303333
C057775benzylparabenbenzylparaben results in increased expression of FASN mRNA22956630
C057775benzylparabenbenzylparaben results in increased expression of FASN mRNA22956630
C013894beta-conglycinin protein, Glycine max"beta-conglycinin protein, Glycine max results in decreased activity of FASN protein"20148945
C013894beta-conglycinin protein, Glycine max"beta-conglycinin protein, Glycine max binds to and results in decreased activity of FASN protein"20148945
D004958EstradiolEstradiol results in decreased expression of FASN mRNA20106945
D004958EstradiolEstradiol results in increased expression of FASN mRNA23019147
D004958EstradiolEstradiol results in decreased expression of FASN mRNA26164745
D004958EstradiolEstradiol results in decreased expression of FASN protein26164745
C023888beta-hexachlorocyclohexanebeta-hexachlorocyclohexane results in increased expression of FASN protein28397872
D001622Betaine[Choline co-treated with Betaine co-treated with Vitamin B 12 co-treated with Folic Acid] affects the reaction [[Dietary Fats co-treated with Dietary Sucrose] affects the methylation of FASN promoter]22648174
C095105bexarotenebexarotene results in increased expression of FASN mRNA16648578|1763041
C095105bexarotene[Tamoxifen co-treated with bexarotene] results in increased expression of FASN mRNA17630414
D001629Bezafibrate[Oleic Acid co-treated with Bezafibrate] results in increased expression of FASN mRNA24534255
D001629BezafibrateBezafibrate results in decreased expression of FASN mRNA19124612
D001629BezafibrateBezafibrate results in decreased expression of FASN protein19124612
D001629BezafibrateBezafibrate results in increased expression of FASN mRNA17118139|1912461
D001629BezafibrateBezafibrate results in increased expression of FASN protein19124612
D001629BezafibrateBezafibrate affects the expression of FASN mRNA17719200
C006780bisphenol Abisphenol A results in decreased expression of FASN mRNA26494506
C006780bisphenol Abisphenol A results in increased activity of FASN protein26494506
C006780bisphenol Abisphenol A affects the expression of FASN mRNA24793377
C006780bisphenol Abisphenol A results in decreased expression of FASN protein27522653
C006780bisphenol Abisphenol A results in increased expression of FASN mRNA27014939|2848355
C006780bisphenol AMIR192 mRNA inhibits the reaction [bisphenol A results in increased expression of FASN mRNA]28483554
C006780bisphenol A"N-piperidinyl-(8-chloro-1-(2,4-dichlorophenyl)-1,4,5,6-tetrahydrobenzo(6,7)cyclohepta(1,2-c)pyrazole-3-carboxamide) inhibits the reaction [bisphenol A results in increased expression of FASN mRNA]"27014939
C006780bisphenol ASREBF1 protein affects the reaction [bisphenol A results in increased expression of FASN mRNA]28483554
C006780bisphenol A[1-Methyl-3-isobutylxanthine co-treated with bisphenol A co-treated with INS protein] results in increased expression of FASN protein26820058
C006780bisphenol Abisphenol A results in decreased methylation of FASN promoter27502578|2879662
C006780bisphenol Abisphenol A results in increased expression of FASN mRNA21932408|2750257
C006780bisphenol Abisphenol A results in increased expression of FASN protein21932408|2879662
C006780bisphenol ASREBF1 mRNA promotes the reaction [bisphenol A results in increased expression of FASN mRNA]27502578
C006780bisphenol ASREBF2 mRNA promotes the reaction [bisphenol A results in increased expression of FASN mRNA]27502578
C006780bisphenol A"[Tetrachlorodibenzodioxin co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Diethylhexyl Phthalate co-treated with bisphenol A] results in decreased expression of FASN mRNA"28433925
C006780bisphenol Abisphenol A affects the expression of FASN mRNA25181051
C006780bisphenol Abisphenol A promotes the reaction [Dietary Fats results in increased expression of FASN mRNA]25112833
C006780bisphenol Abisphenol A promotes the reaction [Dietary Fats results in increased expression of FASN protein]25112833
C006780bisphenol Abisphenol A results in increased expression of FASN mRNA20019905|2511283
C006780bisphenol Abisphenol A results in increased expression of FASN protein25112833
C006780bisphenol Abisphenol A results in increased methylation of FASN gene28505145
C006780bisphenol ADietary Fats promotes the reaction [bisphenol A results in increased expression of FASN mRNA]25112833
C006780bisphenol ADietary Fats promotes the reaction [bisphenol A results in increased expression of FASN protein]25112833
C006780bisphenol Abisphenol A results in increased expression of FASN mRNA26382854
C032688boric acidboric acid inhibits the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased expression of FASN mRNA]28285642
D002065BuspironeBuspirone results in decreased expression of FASN mRNA24136188
C027561butylbenzyl phthalate[1-Methyl-3-isobutylxanthine co-treated with butylbenzyl phthalate co-treated with INS protein] results in increased expression of FASN mRNA26820058
C027561butylbenzyl phthalate[1-Methyl-3-isobutylxanthine co-treated with butylbenzyl phthalate co-treated with INS protein] results in increased expression of FASN protein26820058
C038091butylparabenbutylparaben results in increased expression of FASN mRNA22956630
C038091butylparabenbutylparaben promotes the reaction [Dexamethasone results in increased expression of FASN mRNA]22956630
C038091butylparabenbutylparaben results in increased expression of FASN mRNA22956630
D002104CadmiumCadmium results in increased oxidation of FASN protein24077948
D002104CadmiumCadmium affects the expression of FASN mRNA24095957
D019256Cadmium ChlorideCadmium Chloride results in increased expression of FASN mRNA23741332
D019256Cadmium Chloride[Cadmium Chloride co-treated with methylmercuric chloride] results in decreased expression of FASN mRNA27814245
D019256Cadmium Chloride[MT1 gene mutant form results in increased susceptibility to Cadmium Chloride] which results in decreased expression of FASN mRNA23921151
D019256Cadmium Chloride[MT2 gene mutant form results in increased susceptibility to Cadmium Chloride] which results in decreased expression of FASN mRNA23921151
C040048caffeic acid[Metformin co-treated with caffeic acid] results in decreased expression of FASN protein28576465
C040048caffeic acidcaffeic acid results in decreased expression of FASN mRNA21870829
D002110Caffeine[Caffeine co-treated with coclaurine co-treated with aegeline co-treated with higenamine co-treated with Yohimbine co-treated with Hydrolyzable Tannins] results in decreased expression of FASN mRNA28843594
D002251Carbon TetrachlorideCarbon Tetrachloride results in decreased expression of FASN mRNA27339419
D002251Carbon TetrachlorideCarbon Tetrachloride results in decreased expression of FASN mRNA16239168|1752207
C043211carvedilolcarvedilol inhibits the reaction [Ethanol results in increased expression of FASN mRNA]22413959
D002392Catechin[Catechin co-treated with Dietary Fats] affects the expression of FASN mRNA25861419
D002392CatechinCatechin inhibits the reaction [Dietary Fats results in increased expression of FASN mRNA]23365609
D000068579CelecoxibCelecoxib results in decreased activity of FASN protein19159447
D000068579CelecoxibDinoprostone promotes the reaction [Celecoxib results in decreased activity of FASN protein]19159447
D002518CeramidesFASN protein results in increased abundance of Ceramides26670611
D002569CeruleninCerulenin results in decreased activity of FASN protein12798352
D002569Cerulenin[Cerulenin results in decreased activity of FASN protein] which results in decreased abundance of Phosphorylcholine18723500
D002569CeruleninCerulenin results in decreased activity of FASN protein15707987
D002569CeruleninCerulenin results in decreased expression of FASN mRNA15707987
D002569CeruleninCerulenin results in decreased activity of FASN protein17283163|2037280
D048271ChitosanChitosan inhibits the reaction [Dietary Fats results in increased expression of FASN mRNA]28987369
D048271Chitosan[Fish Oils co-treated with Chitosan] inhibits the reaction [Dietary Fats results in increased expression of FASN mRNA]28987369
D002719ChlormethiazoleChlormethiazole inhibits the reaction [Ethanol results in decreased expression of FASN protein]24892905
D020111Chlorodiphenyl (54% Chlorine)Chlorodiphenyl (54% Chlorine) results in decreased expression of FASN mRNA23650126
D002726Chlorogenic AcidChlorogenic Acid results in decreased expression of FASN mRNA21870829
C100187chloropicrinchloropicrin results in decreased expression of FASN mRNA26352163
D002791Cholesterol, Dietary"[Cholesterol, Dietary co-treated with Dietary Carbohydrates] results in increased expression of FASN mRNA"22579924
D002791Cholesterol, Dietary"Cholesterol, Dietary results in increased expression of FASN mRNA"22579924
D002791Cholesterol, Dietary"Cholesterol, Dietary results in increased expression of FASN protein"27019295
D002791Cholesterol, Dietary"oleuropein inhibits the reaction [Cholesterol, Dietary results in increased expression of FASN protein]"27019295
D002791Cholesterol, Dietary"Plant Preparations inhibits the reaction [Cholesterol, Dietary results in increased expression of FASN mRNA]"22579924
D002793Cholic Acids[1-Naphthylisothiocyanate co-treated with Cholic Acids] affects the expression of FASN mRNA27344345
D002793Cholic Acids[Cyclosporine co-treated with Cholic Acids] affects the expression of FASN mRNA27344345
D002794Choline[Choline deficiency co-treated with Methionine deficiency] results in decreased expression of FASN mRNA25178843
D002794Choline"[Methionine deficiency co-treated with Choline deficiency co-treated with 3,4,5,3',4'-pentachlorobiphenyl] results in decreased expression of FASN mRNA"28163111
D002794Choline[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of FASN gene20938992
D002794Choline[Methionine deficiency co-treated with Choline deficiency] results in decreased expression of FASN mRNA23038002
D002794CholineMethionine inhibits the reaction [[Choline deficiency co-treated with Methionine deficiency] results in decreased expression of FASN mRNA]25178843
D002794Choline[Choline co-treated with Betaine co-treated with Vitamin B 12 co-treated with Folic Acid] affects the reaction [[Dietary Fats co-treated with Dietary Sucrose] affects the methylation of FASN promoter]22648174
D002922CiguatoxinsCiguatoxins affects the expression of FASN mRNA18353800
D002994ClofibrateClofibrate results in decreased expression of FASN mRNA17495091
D002994ClofibrateClofibrate results in decreased expression of FASN mRNA17585979|2381119
D002994ClofibrateClofibrate results in decreased expression of FASN mRNA17522070|1922454
D002994ClofibrateClofibrate results in decreased expression of FASN protein8240402
D002994ClofibrateClofibrate results in increased expression of FASN protein6821269
D003024ClozapineClozapine results in increased expression of FASN mRNA16027736|1705236
C007095cobaltiprotoporphyrincobaltiprotoporphyrin inhibits the reaction [LEP gene mutant form results in increased expression of FASN protein]23839791
C007095cobaltiprotoporphyrin[SIRT1 gene mutant form co-treated with cobaltiprotoporphyrin] results in increased expression of FASN mRNA26026874
C007095cobaltiprotoporphyrintin mesoporphyrin inhibits the reaction [cobaltiprotoporphyrin inhibits the reaction [LEP gene mutant form results in increased expression of FASN protein]]23839791
C018021cobaltous chloridecobaltous chloride results in decreased expression of FASN mRNA19320972
C018021cobaltous chloridecobaltous chloride results in decreased expression of FASN mRNA24386269
C004690coclaurine[Caffeine co-treated with coclaurine co-treated with aegeline co-treated with higenamine co-treated with Yohimbine co-treated with Hydrolyzable Tannins] results in decreased expression of FASN mRNA28843594
D009249NADPNADP binds to and results in increased activity of FASN protein25526675
D003300Copper[NSC 689534 binds to Copper] which results in decreased expression of FASN mRNA20971185
D003300Copper[Thiosemicarbazones binds to Copper] which results in increased expression of FASN protein20931265
D003300CopperCopper results in decreased expression of FASN mRNA17205981
D003300Copper[Copper co-treated with Dietary Sucrose] results in increased expression of FASN mRNA26033743
D003300Copper[Copper deficiency co-treated with Fructose] results in increased expression of FASN protein21781943
D003300CopperCopper deficiency results in increased expression of FASN mRNA11110846
D003300Copper[gadolinium chloride co-treated with Fructose co-treated with Copper deficiency] results in decreased expression of FASN mRNA25813056
C098468copper histidinebathocuproine sulfonate inhibits the reaction [copper histidine results in increased expression of FASN mRNA]24170205
C098468copper histidinecopper histidine results in increased expression of FASN mRNA24170205
D019327Copper SulfateCopper Sulfate results in decreased expression of FASN mRNA24854705
D019327Copper SulfateSodium Selenite inhibits the reaction [Copper Sulfate results in decreased expression of FASN mRNA]24854705
D019327Copper SulfateCopper Sulfate results in decreased expression of FASN mRNA19549813
D019327Copper SulfateCopper Sulfate results in decreased expression of FASN mRNA23660017
D019327Copper SulfateCopper Sulfate results in decreased expression of FASN protein23660017
D003314Corn OilCorn Oil affects the expression of FASN mRNA16360708
D003345Corticosterone[Corticosterone co-treated with oleoyl-estrone] affects the expression of FASN mRNA19545626
C030123coumarincoumarin affects the expression of FASN mRNA16963487
C551994crizotinibcrizotinib results in increased expression of FASN mRNA23707608
C029892cupric chloridecupric chloride results in increased expression of FASN mRNA24650576
D003474CurcuminCurcumin affects the expression of FASN mRNA27208389
D003474CurcuminCurcumin affects the expression of FASN protein27208389
D003474CurcuminCurcumin results in decreased expression of FASN mRNA27208389
C057862cyanoginosin LRcyanoginosin LR results in decreased expression of FASN protein26984711
C057862cyanoginosin LRcyanoginosin LR results in increased expression of FASN mRNA25497113
D003513CycloheximideCycloheximide inhibits the reaction [Calcitriol results in decreased expression of FASN mRNA]12798352
D016572Cyclosporine[Cyclosporine co-treated with Cholic Acids] affects the expression of FASN mRNA27344345
D016572CyclosporineCyclosporine results in decreased expression of FASN mRNA20106945|2890348
D016572CyclosporineCyclosporine results in increased expression of FASN protein28903485
D016572CyclosporineCyclosporine results in decreased expression of FASN mRNA19224547
C037304cyhalothrincyhalothrin results in increased expression of FASN mRNA27348886
C037304cyhalothrincyhalothrin results in increased expression of FASN protein27348886
C093628cyproconazolecyproconazole results in increased expression of FASN mRNA29038839
C010902decabromobiphenyl etherdecabromobiphenyl ether results in decreased expression of FASN mRNA23640034
D0174851-Deoxynojirimycin1-Deoxynojirimycin inhibits the reaction [Dietary Fats results in increased expression of FASN mRNA]25445511
D003907Dexamethasone[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] results in increased expression of FASN mRNA26200599
D003907DexamethasoneDexamethasone results in increased expression of FASN mRNA25047013
D003907DexamethasoneDichlorodiphenyl Dichloroethylene promotes the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] results in increased expression of FASN mRNA]26200599
D003907DexamethasoneFASN protein results in decreased susceptibility to [INS protein co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone]26670611
D003907Dexamethasone[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of FASN mRNA27475717
D003907Dexamethasone[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of FASN protein25559859|2747571
D003907Dexamethasoneandrographolide inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of FASN mRNA]27475717
D003907Dexamethasoneandrographolide inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of FASN protein]27475717
D003907Dexamethasoneboric acid inhibits the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased expression of FASN mRNA]28285642
D003907Dexamethasonebutylparaben promotes the reaction [Dexamethasone results in increased expression of FASN mRNA]22956630
D003907Dexamethasone[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased expression of FASN mRNA28285642
D003907DexamethasoneDexamethasone results in increased expression of FASN mRNA22956630
D003907Dexamethasone[Quercetin co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in decreased expression of FASN protein18586010
D003907Dexamethasonesilybin inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of FASN protein]25559859
D003907Dexamethasonesodium pentaborate inhibits the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased expression of FASN mRNA]28285642
D003907DexamethasoneDexamethasone results in increased expression of FASN mRNA17522070
C042577diallyl trisulfide[diallyl trisulfide results in decreased expression of [CEBPA protein co-treated with CEBPB protein co-treated with PPARG protein]] which results in decreased expression of FASN22137902
D003976DiazinonDiazinon results in increased methylation of FASN gene22964155
C041517dibenzo(a,l)pyrene"dibenzo(a,l)pyrene results in decreased expression of FASN mRNA"16269432
D003993Dibutyl PhthalateDibutyl Phthalate results in decreased expression of FASN mRNA21266533
D003999Dichloroacetic AcidDichloroacetic Acid results in increased expression of FASN mRNA28962523
D002945Cisplatin[4-methylene-2-octyl-5-oxofuran-3-carboxylic acid co-treated with Cisplatin] results in decreased expression of FASN protein21442130
D002945Cisplatin[4-methylene-2-octyl-5-oxofuran-3-carboxylic acid results in decreased activity of FASN protein] which results in increased susceptibility to Cisplatin21442130
D002945Cisplatin[Cisplatin co-treated with jinfukang] results in increased expression of FASN mRNA27392435
D002945CisplatinCisplatin results in decreased expression of FASN mRNA27594783
D002945CisplatinCisplatin results in increased expression of FASN protein22023808
D003633Dichlorodiphenyl DichloroethyleneDichlorodiphenyl Dichloroethylene promotes the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] results in increased expression of FASN mRNA]26200599
D003633Dichlorodiphenyl DichloroethyleneDichlorodiphenyl Dichloroethylene results in increased expression of FASN protein28397872
D003633Dichlorodiphenyl Dichloroethylene[Dietary Fats co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of FASN mRNA25541407
D004008DiclofenacDiclofenac results in decreased expression of FASN mRNA19022234
C000944dicrotophosdicrotophos results in increased expression of FASN mRNA28302478
D018119Stavudine[Stavudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of FASN mRNA11741158
D018119Stavudine[Stavudine co-treated with Lamivudine] results in increased expression of FASN mRNA11741158
D018119StavudineStavudine results in decreased expression of FASN protein15722030
D019259Lamivudine[Stavudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of FASN mRNA11741158
D019259Lamivudine[Stavudine co-treated with Lamivudine] results in increased expression of FASN mRNA11741158
D019259Lamivudine[Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of FASN mRNA11741158
D019259Lamivudine[Zidovudine co-treated with Lamivudine] results in increased expression of FASN mRNA11741158
D004040Dietary CarbohydratesDietary Carbohydrates affects the expression of FASN mRNA20110567
D004040Dietary Carbohydrates"[Cholesterol, Dietary co-treated with Dietary Carbohydrates] results in increased expression of FASN mRNA"22579924
D004041Dietary FatsDietary Fats results in increased expression of FASN mRNA24709573
D004041Dietary Fats[Fructose co-treated with Dietary Fats co-treated with TO-901317] results in increased expression of FASN mRNA19509184
D004041Dietary Fatszerumbone inhibits the reaction [Dietary Fats results in increased expression of FASN mRNA]24709573
D004041Dietary Fats1-Deoxynojirimycin inhibits the reaction [Dietary Fats results in increased expression of FASN mRNA]25445511
D004041Dietary Fats"2,4,5,2',4',5'-hexachlorobiphenyl promotes the reaction [Dietary Fats results in increased expression of FASN mRNA]"23618531
D004041Dietary Fats[AGT protein affects the susceptibility to Dietary Fats] which affects the expression of FASN mRNA26704350
D004041Dietary FatsANGPTL4 protein modified form affects the reaction [Dietary Fats affects the expression of FASN mRNA]28842503
D004041Dietary Fats[Catechin co-treated with Dietary Fats] affects the expression of FASN mRNA25861419
D004041Dietary FatsDietary Fats affects the expression of FASN mRNA19680557|2011056
D004041Dietary Fats[Dietary Fats co-treated with aroclor 1260] results in decreased expression of FASN mRNA24998970
D004041Dietary Fats[Dietary Fats co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of FASN mRNA25541407
D004041Dietary Fats[Dietary Fats co-treated with Dietary Sucrose] results in decreased expression of FASN mRNA28433925
D004041Dietary Fats[Dietary Fats co-treated with Dietary Sucrose] results in increased expression of FASN mRNA21462320
D004041Dietary Fats[Dietary Fats co-treated with Streptozocin] results in decreased expression of FASN mRNA27769711
D004041Dietary Fats"Dietary Fats promotes the reaction [2,4,5,2',4',5'-hexachlorobiphenyl results in increased expression of FASN mRNA]"23618531
D004041Dietary FatsDietary Fats results in decreased expression of FASN mRNA18042831|1845759
D004041Dietary FatsDietary Fats results in decreased expression of FASN protein28077572
D004041Dietary FatsDietary Fats results in increased expression of FASN mRNA17932310|1829274
D004041Dietary FatsDietary Fats results in increased expression of FASN protein22447684|2382154
D004041Dietary Fatsesculetin promotes the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of FASN mRNA]27769711
D004041Dietary FatsFGF15 gene mutant form inhibits the reaction [Dietary Fats results in decreased expression of FASN mRNA]28673684
D004041Dietary Fatsgastrodin inhibits the reaction [Dietary Fats results in increased expression of FASN mRNA]26634892
D004041Dietary Fatsnaringin inhibits the reaction [Dietary Fats results in increased expression of FASN mRNA]22198281
D004041Dietary FatsNFE2L2 protein affects the reaction [Dietary Fats results in increased expression of FASN mRNA]27311796
D004041Dietary FatsPlant Extracts inhibits the reaction [Dietary Fats results in increased expression of FASN mRNA]22967722
D004041Dietary Fats[Plant Preparations co-treated with Dietary Fats] affects the expression of FASN mRNA25861419
D004041Dietary FatsPPARGC1B protein promotes the reaction [Dietary Fats results in increased expression of FASN mRNA]17932310
D004041Dietary FatsQuercetin inhibits the reaction [[Dietary Fats co-treated with Dietary Sucrose] results in increased expression of FASN mRNA]21462320
D004041Dietary FatsQuercetin inhibits the reaction [Dietary Fats results in increased expression of FASN mRNA]22447684|2402568
D004041Dietary FatsQuercetin inhibits the reaction [Dietary Fats results in increased expression of FASN protein]22447684
D004041Dietary FatsRALBP1 protein affects the reaction [Dietary Fats results in increased expression of FASN protein]23821548
D004041Dietary Fatsrimonabant inhibits the reaction [Dietary Fats results in decreased expression of FASN mRNA]19030233
D004041Dietary FatsTetrachlorodibenzodioxin inhibits the reaction [Dietary Fats results in increased expression of FASN mRNA]27713108
D004041Dietary Fatsbisphenol A promotes the reaction [Dietary Fats results in increased expression of FASN mRNA]25112833
D004041Dietary Fatsbisphenol A promotes the reaction [Dietary Fats results in increased expression of FASN protein]25112833
D004041Dietary FatsCatechin inhibits the reaction [Dietary Fats results in increased expression of FASN mRNA]23365609
D004041Dietary FatsChitosan inhibits the reaction [Dietary Fats results in increased expression of FASN mRNA]28987369
D004041Dietary Fats[Choline co-treated with Betaine co-treated with Vitamin B 12 co-treated with Folic Acid] affects the reaction [[Dietary Fats co-treated with Dietary Sucrose] affects the methylation of FASN promoter]22648174
D004041Dietary FatsDietary Fats analog results in decreased expression of FASN mRNA12669817
D004041Dietary Fats[Dietary Fats co-treated with Dietary Sucrose] affects the expression of FASN mRNA22648174
D004041Dietary Fats[Dietary Fats co-treated with Dietary Sucrose] affects the methylation of FASN promoter22648174
D004041Dietary Fats[Dietary Fats co-treated with Dietary Sucrose] results in decreased expression of FASN mRNA22738222
D004041Dietary Fats[Dietary Fats co-treated with Ethanol] results in increased expression of FASN mRNA24275070
D004041Dietary FatsDietary Fats promotes the reaction [bisphenol A results in increased expression of FASN mRNA]25112833
D004041Dietary FatsDietary Fats promotes the reaction [bisphenol A results in increased expression of FASN protein]25112833
D004041Dietary FatsDietary Fats results in decreased expression of FASN mRNA20729114|2368475
D004041Dietary FatsDietary Fats results in increased activity of FASN protein23537522
D004041Dietary FatsDietary Fats results in increased expression of FASN mRNA23365609|2427507
D004041Dietary FatsDietary Fats results in increased expression of FASN protein23026700|2511283
D004041Dietary Fats[Dietary Sucrose co-treated with Dietary Fats co-treated with pterostilbene] affects the activity of FASN protein25083823
D004041Dietary Fats[Dietary Sucrose co-treated with Dietary Fats] results in decreased expression of FASN mRNA23529981
D004041Dietary Fats[Fish Oils co-treated with Chitosan] inhibits the reaction [Dietary Fats results in increased expression of FASN mRNA]28987369
D004041Dietary FatsFish Oils inhibits the reaction [Dietary Fats results in increased expression of FASN mRNA]28987369
D004041Dietary FatsOlive Oil inhibits the reaction [Dietary Fats results in decreased expression of FASN mRNA]24450870
D004041Dietary FatsPlant Extracts inhibits the reaction [Dietary Fats results in increased expression of FASN mRNA]23365609
D004041Dietary FatsPlant Extracts inhibits the reaction [Dietary Fats results in increased expression of FASN protein]23026700
D019422Dietary Sucrose[Dietary Fats co-treated with Dietary Sucrose] results in decreased expression of FASN mRNA28433925
D019422Dietary Sucrose[Dietary Fats co-treated with Dietary Sucrose] results in increased expression of FASN mRNA21462320
D019422Dietary SucroseQuercetin inhibits the reaction [[Dietary Fats co-treated with Dietary Sucrose] results in increased expression of FASN mRNA]21462320
D019422Dietary Sucrose[Choline co-treated with Betaine co-treated with Vitamin B 12 co-treated with Folic Acid] affects the reaction [[Dietary Fats co-treated with Dietary Sucrose] affects the methylation of FASN promoter]22648174
D019422Dietary Sucrose[Copper co-treated with Dietary Sucrose] results in increased expression of FASN mRNA26033743
D019422Dietary Sucrose[Dietary Fats co-treated with Dietary Sucrose] affects the expression of FASN mRNA22648174
D019422Dietary Sucrose[Dietary Fats co-treated with Dietary Sucrose] affects the methylation of FASN promoter22648174
D019422Dietary Sucrose[Dietary Fats co-treated with Dietary Sucrose] results in decreased expression of FASN mRNA22738222
D019422Dietary Sucrose[Dietary Sucrose co-treated with Dietary Fats co-treated with pterostilbene] affects the activity of FASN protein25083823
D019422Dietary Sucrose[Dietary Sucrose co-treated with Dietary Fats] results in decreased expression of FASN mRNA23529981
D004051Diethylhexyl PhthalateDiethylhexyl Phthalate results in decreased expression of FASN mRNA19245819
D004051Diethylhexyl Phthalate"[Tetrachlorodibenzodioxin co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Diethylhexyl Phthalate co-treated with bisphenol A] results in decreased expression of FASN mRNA"28433925
C014476diethyl maleatediethyl maleate results in decreased expression of FASN mRNA21161181
D004052Diethylnitrosamine[Diethylnitrosamine co-treated with Thioacetamide] results in decreased expression of FASN mRNA28943392
D004075DiglyceridesFASN protein results in increased abundance of Diglycerides26670611
C039060dihydroartemisinin[dihydroartemisinin co-treated with NR1H4 protein] inhibits the reaction [Ethanol results in increased expression of FASN mRNA]27939985
C039060dihydroartemisinin[dihydroartemisinin co-treated with NR1H4 protein] inhibits the reaction [Ethanol results in increased expression of FASN protein]27939985
C039060dihydroartemisinindihydroartemisinin inhibits the reaction [Ethanol results in increased expression of FASN mRNA]27939985
C039060dihydroartemisinindihydroartemisinin inhibits the reaction [Ethanol results in increased expression of FASN protein]27939985
D002117CalcitriolCalcitriol results in decreased expression of FASN mRNA12798352
D002117CalcitriolCycloheximide inhibits the reaction [Calcitriol results in decreased expression of FASN mRNA]12798352
D0151279,10-Dimethyl-1,2-benzanthracene"[9,10-Dimethyl-1,2-benzanthracene co-treated with Isoflavones] results in increased expression of FASN protein"22248470
D0151279,10-Dimethyl-1,2-benzanthracene"9,10-Dimethyl-1,2-benzanthracene results in increased expression of FASN protein"22248470
C550453dioxinodehydroeckoldioxinodehydroeckol results in decreased expression of FASN mRNA20385110
C076126disodium (R,R)-5-(2-((2-(3-chlorophenyl)-2-hydroxyethyl)-amino)propyl)-1,3-benzodioxole-2,3-dicarboxylate"disodium (R,R)-5-(2-((2-(3-chlorophenyl)-2-hydroxyethyl)-amino)propyl)-1,3-benzodioxole-2,3-dicarboxylate results in increased expression of FASN mRNA"20184727
D004317DoxorubicinDoxorubicin results in increased expression of FASN mRNA17089011
D004317DoxorubicinFASN protein inhibits the reaction [Doxorubicin results in increased cleavage of PARP1 protein]18281512
D004317DoxorubicinFASN protein results in decreased susceptibility to Doxorubicin18281512
D004317Doxorubicinorlistat inhibits the reaction [FASN protein results in decreased susceptibility to Doxorubicin]18281512
D004365Drugs, Chinese Herbal"Drugs, Chinese Herbal results in decreased expression of FASN mRNA"27369806
D015118Eicosapentaenoic AcidEicosapentaenoic Acid results in decreased expression of FASN mRNA19159447
D004791Enzyme Inhibitors[Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation of FASN protein23301498
C045651epigallocatechin gallateepigallocatechin gallate results in decreased expression of FASN mRNA20816778
C045651epigallocatechin gallateepigallocatechin gallate results in decreased expression of FASN mRNA16988119
C109476epoxiconazoleepoxiconazole results in increased expression of FASN mRNA29038839
D004917ErythromycinErythromycin results in increased expression of FASN mRNA27503388
D004917Erythromycin[Penicillin G co-treated with Erythromycin] results in increased expression of FASN mRNA27503388
D004918Erythromycin EstolateErythromycin Estolate results in decreased expression of FASN mRNA17522070
C007628esculetinesculetin promotes the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of FASN mRNA]27769711
D000431Ethanol[dihydroartemisinin co-treated with NR1H4 protein] inhibits the reaction [Ethanol results in increased expression of FASN mRNA]27939985
D000431Ethanol[dihydroartemisinin co-treated with NR1H4 protein] inhibits the reaction [Ethanol results in increased expression of FASN protein]27939985
D000431Ethanoldihydroartemisinin inhibits the reaction [Ethanol results in increased expression of FASN mRNA]27939985
D000431Ethanoldihydroartemisinin inhibits the reaction [Ethanol results in increased expression of FASN protein]27939985
D000431EthanolEthanol results in increased expression of FASN mRNA24144995|2793998
D000431EthanolEthanol results in increased expression of FASN protein27939985
D000431EthanolNR1H4 protein inhibits the reaction [Ethanol results in increased expression of FASN mRNA]27939985
D000431EthanolNR1H4 protein inhibits the reaction [Ethanol results in increased expression of FASN protein]27939985
D000431Ethanolobeticholic acid inhibits the reaction [Ethanol results in increased expression of FASN protein]27939985
D000431Ethanolacanthoic acid inhibits the reaction [Ethanol results in increased expression of FASN mRNA]28964808
D000431Ethanolacanthoic acid inhibits the reaction [Ethanol results in increased expression of FASN protein]28964808
D000431Ethanol[ADORA1 gene mutant form results in increased susceptibility to Ethanol] which results in increased expression of FASN mRNA23692951
D000431EthanolChlormethiazole inhibits the reaction [Ethanol results in decreased expression of FASN protein]24892905
D000431EthanolEthanol inhibits the reaction [Fish Oils results in decreased expression of FASN mRNA]18620774
D000431EthanolEthanol inhibits the reaction [pirinixic acid results in decreased expression of FASN mRNA]18620774
D000431EthanolEthanol results in decreased expression of FASN mRNA22173916
D000431EthanolEthanol results in decreased expression of FASN protein24892905|2888257
D000431EthanolEthanol results in increased expression of FASN mRNA12036955|1862077
D000431EthanolEthanol results in increased expression of FASN protein28964808
D000431Ethanolgadolinium chloride promotes the reaction [Ethanol results in decreased expression of FASN protein]28882574
D000431EthanolPER1 gene mutant form inhibits the reaction [Ethanol results in increased expression of FASN mRNA]24144995
D000431Ethanolresveratrol inhibits the reaction [Ethanol results in increased expression of FASN mRNA]18755807
D000431Ethanolrosiglitazone inhibits the reaction [Ethanol results in decreased expression of FASN mRNA]22173916
D000431Ethanolcarvedilol inhibits the reaction [Ethanol results in increased expression of FASN mRNA]22413959
D000431Ethanol[Dietary Fats co-treated with Ethanol] results in increased expression of FASN mRNA24275070
D000431EthanolEthanol results in increased expression of FASN mRNA22413959|2414611
D000431Ethanol[Fish Oils co-treated with Ethanol] results in increased expression of FASN mRNA17347304
D000431Ethanol[Oleic Acid co-treated with Palmitic Acid] inhibits the reaction [Ethanol results in increased expression of FASN mRNA]26854922
D000431EthanolScopoletin inhibits the reaction [Ethanol results in increased expression of FASN mRNA]26115886
D000431EthanolSilymarin inhibits the reaction [Ethanol results in increased expression of FASN mRNA]26115886
D004997Ethinyl Estradiol[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in decreased expression of FASN mRNA17942748
D004997Ethinyl EstradiolEthinyl Estradiol affects the expression of FASN mRNA16079270
D004997Ethinyl EstradiolEthinyl Estradiol results in decreased expression of FASN mRNA15953391|1710823
D004997Ethinyl EstradiolEthinyl Estradiol results in increased expression of FASN mRNA16174780
C024565ethylene dichlorideethylene dichloride results in decreased expression of FASN mRNA28189721
D005020Ethyl MethanesulfonateEthyl Methanesulfonate results in decreased expression of FASN mRNA23649840
D005047EtoposideEtoposide results in increased expression of FASN mRNA17089011
D005054EugenolEugenol results in decreased expression of FASN mRNA21870829
D005227Fatty AcidsFASN protein results in increased chemical synthesis of Fatty Acids18723500
D005227Fatty Acids[Fatty Acids co-treated with INS protein] results in increased expression of FASN mRNA24648896
D005227Fatty Acids[Fatty Acids co-treated with INS protein] results in increased expression of FASN protein24648896
D005227Fatty Acids[orlistat results in decreased activity of FASN protein] which results in decreased abundance of Fatty Acids18723500
D005227Fatty Acids[orlistat results in decreased activity of FASN protein] which results in decreased chemical synthesis of Fatty Acids17012255
D005227Fatty AcidsQuercetin inhibits the reaction [[Fatty Acids co-treated with INS protein] results in increased expression of FASN mRNA]24648896
D005227Fatty AcidsQuercetin inhibits the reaction [[Fatty Acids co-treated with INS protein] results in increased expression of FASN protein]24648896
D005228Fatty Acids, Essential"Fatty Acids, Essential deficiency results in increased expression of FASN mRNA"23333450
D005228Fatty Acids, Essential"Fatty Acids, Essential deficiency results in increased expression of FASN protein"23333450
D005228Fatty Acids, Essential"NR1H2 gene mutant form inhibits the reaction [Fatty Acids, Essential deficiency results in increased expression of FASN mRNA]"23333450
D005228Fatty Acids, Essential"NR1H2 gene mutant form inhibits the reaction [Fatty Acids, Essential deficiency results in increased expression of FASN protein]"23333450
D005228Fatty Acids, Essential"NR1H3 gene mutant form inhibits the reaction [Fatty Acids, Essential deficiency results in increased expression of FASN mRNA]"23333450
D005228Fatty Acids, Essential"NR1H3 gene mutant form inhibits the reaction [Fatty Acids, Essential deficiency results in increased expression of FASN protein]"23333450
D005230Fatty Acids, Nonesterified"FASN protein promotes the reaction [rosiglitazone promotes the reaction [PPARG protein results in increased abundance of Fatty Acids, Nonesterified]]"26670611
D005230Fatty Acids, Nonesterified"FASN protein results in increased abundance of Fatty Acids, Nonesterified"26670611
D005230Fatty Acids, Nonesterified"Fatty Acids, Nonesterified results in increased expression of FASN mRNA"23465592
D005230Fatty Acids, Nonesterified"Protein Kinase Inhibitors inhibits the reaction [FASN protein results in increased abundance of Fatty Acids, Nonesterified]"26670611
D005230Fatty Acids, Nonesterified"S-allylcysteine inhibits the reaction [Fatty Acids, Nonesterified results in increased expression of FASN mRNA]"23465592
D005230Fatty Acids, Nonesterified"[orlistat results in decreased activity of FASN protein] which affects the abundance of Fatty Acids, Nonesterified"21213365
D011345Fenofibrate[Oleic Acid co-treated with Fenofibrate] affects the expression of FASN mRNA24534255
D011345FenofibrateFenofibrate results in increased expression of FASN mRNA17118139|2306369
D011345FenofibrateNR1H2 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of FASN mRNA]23063693
D011345FenofibrateNR1H3 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of FASN mRNA]23063693
D011345FenofibratePPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of FASN mRNA]23063693
D011345Fenofibrate[Fenofibrate co-treated with resveratrol] inhibits the reaction [Fructose results in increased expression of FASN mRNA]26973390
D011345FenofibrateFenofibrate inhibits the reaction [Fructose results in increased expression of FASN mRNA]26973390
C004999ferulic acidferulic acid results in decreased expression of FASN mRNA21870829
C082360fipronilfipronil results in increased expression of FASN mRNA27103584
C082360fipronilfipronil results in increased expression of FASN protein27103584
D005395Fish OilsEthanol inhibits the reaction [Fish Oils results in decreased expression of FASN mRNA]18620774
D005395Fish OilsFish Oils results in decreased expression of FASN mRNA18620774
D005395Fish OilsFish Oils results in decreased expression of FASN protein29142166
D005395Fish Oils[Fish Oils co-treated with Chitosan] inhibits the reaction [Dietary Fats results in increased expression of FASN mRNA]28987369
D005395Fish Oils[Fish Oils co-treated with Ethanol] results in increased expression of FASN mRNA17347304
D005395Fish OilsFish Oils inhibits the reaction [Dietary Fats results in increased expression of FASN mRNA]28987369
D005395Fish OilsFish Oils results in decreased expression of FASN mRNA10787435|1565413
D005492Folic Acid[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of FASN gene20938992
D005492Folic Acid[Choline co-treated with Betaine co-treated with Vitamin B 12 co-treated with Folic Acid] affects the reaction [[Dietary Fats co-treated with Dietary Sucrose] affects the methylation of FASN promoter]22648174
D005557FormaldehydeFormaldehyde results in decreased expression of FASN mRNA23649840
D005632Fructose[Fructose co-treated with Dietary Fats co-treated with TO-901317] results in increased expression of FASN mRNA19509184
D005632FructoseFGF21 gene mutant form inhibits the reaction [Fructose results in increased expression of FASN mRNA]28123933
D005632FructoseFructose results in increased expression of FASN mRNA15066988|2269881
D005632FructoseFructose results in increased expression of FASN protein27531227|2825778
D005632FructosePhenylbutyrates inhibits the reaction [Fructose results in increased expression of FASN mRNA]22698815
D005632FructosePlant Preparations inhibits the reaction [Fructose results in increased expression of FASN protein]27531227
D005632FructoseSCD1 gene mutant form inhibits the reaction [Fructose results in increased expression of FASN mRNA]15066988
D005632FructoseTriolein inhibits the reaction [SCD1 gene mutant form inhibits the reaction [Fructose results in increased expression of FASN mRNA]]15066988
D005632FructoseTriolein promotes the reaction [Fructose results in increased expression of FASN mRNA]15066988
D005632Fructose[Copper deficiency co-treated with Fructose] results in increased expression of FASN protein21781943
D005632Fructose[Fenofibrate co-treated with resveratrol] inhibits the reaction [Fructose results in increased expression of FASN mRNA]26973390
D005632FructoseFenofibrate inhibits the reaction [Fructose results in increased expression of FASN mRNA]26973390
D005632FructoseFructose results in increased activity of FASN protein8759368|9566986
D005632FructoseFructose results in increased expression of FASN mRNA12065722|1834647
D005632FructoseFructose results in increased expression of FASN protein21781943
D005632Fructose[gadolinium chloride co-treated with Fructose co-treated with Copper deficiency] results in decreased expression of FASN mRNA25813056
D005632Fructoseresveratrol inhibits the reaction [Fructose results in increased expression of FASN mRNA]26973390
D005632Fructoserosiglitazone inhibits the reaction [Fructose results in increased expression of FASN mRNA]19196556
D005632FructoseTea inhibits the reaction [Fructose results in increased expression of FASN mRNA]19193814
C070081fulvestrantfulvestrant inhibits the reaction [Norethynodrel results in increased activity of FASN protein]15870863
C039281furanfuran results in decreased expression of FASN mRNA26194646
C038958gadolinium chloridegadolinium chloride promotes the reaction [Ethanol results in decreased expression of FASN protein]28882574
C038958gadolinium chloride[gadolinium chloride co-treated with Fructose co-treated with Copper deficiency] results in decreased expression of FASN mRNA25813056
C045345gastrodingastrodin inhibits the reaction [Dietary Fats results in increased expression of FASN mRNA]26634892
D019833GenisteinGenistein results in increased expression of FASN mRNA22228119
D019833Genistein[Genistein co-treated with mono-(2-ethylhexyl)phthalate] results in increased expression of FASN mRNA27181934
D019833GenisteinGenistein results in increased expression of FASN mRNA27181934
C007845gingerolgingerol results in decreased expression of FASN mRNA26498061
C007845gingerolgingerol results in decreased expression of FASN protein26498061
D005897GlafenineGlafenine results in increased expression of FASN mRNA24136188
D005944GlucosamineGlucosamine results in increased expression of FASN mRNA22096489
D005947GlucoseAllopurinol inhibits the reaction [Glucose results in increased expression of FASN protein]23647015
D005947GlucoseGlucose results in increased expression of FASN protein18482975|2364701
D005947Glucose[Glucose results in increased expression of FASN protein] which results in increased abundance of Triglycerides18482975
D005947GlucosePRKAA2 protein promotes the reaction [SIRT1 protein inhibits the reaction [Glucose results in increased expression of FASN protein]]18482975
D005947GlucoseQuercetin inhibits the reaction [Glucose results in increased expression of FASN protein]23647015
D005947Glucose[resveratrol results in increased activity of SIRT1 protein] inhibits the reaction [[Glucose results in increased expression of FASN protein] which results in increased abundance of Triglycerides]18482975
D005947GlucoseSIRT1 protein inhibits the reaction [Glucose results in increased expression of FASN protein]18482975
D005947GlucoseGlucose results in increased expression of FASN mRNA15066988
D005947GlucoseAllopurinol inhibits the reaction [Glucose results in increased expression of FASN protein]23647015
D005947GlucoseGlucose results in increased expression of FASN protein23647015
D005947GlucoseQuercetin inhibits the reaction [Glucose results in increased expression of FASN protein]23647015
D005978GlutathioneGlutathione inhibits the reaction [Alcohols results in increased expression of FASN protein]28803762
D005978GlutathioneGlutathione deficiency results in decreased expression of FASN mRNA20621112
D006220HaloperidolHaloperidol results in increased expression of FASN mRNA16027736
D006569HesperidinHesperidin affects the reaction [LEPR protein affects the activity of FASN protein]16427799
C012348higenamine[Caffeine co-treated with coclaurine co-treated with aegeline co-treated with higenamine co-treated with Yohimbine co-treated with Hydrolyzable Tannins] results in decreased expression of FASN mRNA28843594
D066248High Fructose Corn SyrupHigh Fructose Corn Syrup results in increased expression of FASN mRNA25238689
D066248High Fructose Corn Syrupresveratrol inhibits the reaction [High Fructose Corn Syrup results in increased expression of FASN mRNA]25238689
D006834HydrazinesHydrazines results in decreased expression of FASN mRNA21647536
D006834HydrazinesHydrazines results in decreased expression of FASN protein21647536
D006861Hydrogen PeroxideHydrogen Peroxide results in increased expression of FASN mRNA26846883
D047348Hydrolyzable Tannins[Caffeine co-treated with coclaurine co-treated with aegeline co-treated with higenamine co-treated with Yohimbine co-treated with Hydrolyzable Tannins] results in decreased expression of FASN mRNA28843594
D007052IbuprofenIbuprofen affects the expression of FASN protein18351690
D007052IbuprofenIbuprofen results in decreased expression of FASN mRNA18351690
D019469IndinavirIndinavir results in increased expression of FASN mRNA11741158
D019469Indinavir[Stavudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of FASN mRNA11741158
D019469Indinavir[Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of FASN mRNA11741158
D0150561-Methyl-3-isobutylxanthine[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] results in increased expression of FASN mRNA26200599
D0150561-Methyl-3-isobutylxanthineDichlorodiphenyl Dichloroethylene promotes the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] results in increased expression of FASN mRNA]26200599
D0150561-Methyl-3-isobutylxanthineFASN protein results in decreased susceptibility to [INS protein co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone]26670611
D0150561-Methyl-3-isobutylxanthine[1-Methyl-3-isobutylxanthine co-treated with bisphenol A co-treated with INS protein] results in increased expression of FASN protein26820058
D0150561-Methyl-3-isobutylxanthine[1-Methyl-3-isobutylxanthine co-treated with butylbenzyl phthalate co-treated with INS protein] results in increased expression of FASN mRNA26820058
D0150561-Methyl-3-isobutylxanthine[1-Methyl-3-isobutylxanthine co-treated with butylbenzyl phthalate co-treated with INS protein] results in increased expression of FASN protein26820058
D0150561-Methyl-3-isobutylxanthine[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of FASN mRNA27475717
D0150561-Methyl-3-isobutylxanthine[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of FASN protein25559859|2747571
D0150561-Methyl-3-isobutylxanthineandrographolide inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of FASN mRNA]27475717
D0150561-Methyl-3-isobutylxanthineandrographolide inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of FASN protein]27475717
D0150561-Methyl-3-isobutylxanthineboric acid inhibits the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased expression of FASN mRNA]28285642
D0150561-Methyl-3-isobutylxanthine[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased expression of FASN mRNA28285642
D0150561-Methyl-3-isobutylxanthine[Quercetin co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in decreased expression of FASN protein18586010
D0150561-Methyl-3-isobutylxanthinesilybin inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of FASN protein]25559859
D0150561-Methyl-3-isobutylxanthinesodium pentaborate inhibits the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased expression of FASN mRNA]28285642
D007529Isoflavones"[9,10-Dimethyl-1,2-benzanthracene co-treated with Isoflavones] results in increased expression of FASN protein"22248470
C515747isosteviolisosteviol results in increased expression of FASN mRNA22479612
C544151jinfukang[Cisplatin co-treated with jinfukang] results in increased expression of FASN mRNA27392435
C468270Kangen-karyuKangen-karyu results in decreased expression of FASN mRNA alternative form25031044
D007854LeadLead results in increased expression of FASN mRNA19921347
D001556LindaneLindane affects the activity of FASN protein7535533
C002385linsidominelinsidomine results in increased oxidation of FASN protein28086193
C482199lipopolysaccharide, E coli O55-B5"[trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of FASN mRNA"18930950
D008070LipopolysaccharidesLipopolysaccharides results in decreased expression of FASN mRNA27339419
D008070LipopolysaccharidesLipopolysaccharides results in increased expression of FASN mRNA21689150
D008070LipopolysaccharidesMelatonin inhibits the reaction [Lipopolysaccharides results in increased expression of FASN mRNA]21689150
C054164lipstatinlipstatin analog binds to FASN protein20577697
D008095Lithocholic AcidLithocholic Acid results in decreased expression of FASN mRNA20359477
D008095Lithocholic AcidPregnenolone Carbonitrile inhibits the reaction [Lithocholic Acid results in decreased expression of FASN mRNA]20359477
D019808LosartanLosartan inhibits the reaction [AGT protein results in increased expression of FASN mRNA]19109942
D008148LovastatinLovastatin results in increased expression of FASN mRNA11728391
D008550MelatoninMelatonin inhibits the reaction [Lipopolysaccharides results in increased expression of FASN mRNA]21689150
D008687Metformin[Metformin co-treated with caffeic acid] results in decreased expression of FASN protein28576465
D008687MetforminMetformin results in decreased expression of FASN mRNA20956498
D008687MetforminMetformin results in decreased expression of FASN mRNA21870829
D008687Metformin[Metformin results in increased activity of PRKAA2 protein] which results in decreased activity of FASN protein17635921
D008701MethapyrileneMethapyrilene results in decreased expression of FASN mRNA28935588
D008715Methionine[Choline deficiency co-treated with Methionine deficiency] results in decreased expression of FASN mRNA25178843
D008715Methionine"[Methionine deficiency co-treated with Choline deficiency co-treated with 3,4,5,3',4'-pentachlorobiphenyl] results in decreased expression of FASN mRNA"28163111
D008715Methionine[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of FASN gene20938992
D008715Methionine[Methionine deficiency co-treated with Choline deficiency] results in decreased expression of FASN mRNA23038002
D008715MethionineMethionine deficiency results in decreased expression of FASN mRNA25178843
D008715MethionineMethionine inhibits the reaction [[Choline deficiency co-treated with Methionine deficiency] results in decreased expression of FASN mRNA]25178843
D008727MethotrexateMethotrexate results in decreased expression of FASN mRNA24136188
C445068methyl 2-cyano-3,12-dioxoolean-1,9-dien-28-oate"methyl 2-cyano-3,12-dioxoolean-1,9-dien-28-oate results in decreased expression of FASN mRNA"20372807
C004925methylmercuric chloridemethylmercuric chloride affects the expression of FASN protein27012723
C004925methylmercuric chloride[Cadmium Chloride co-treated with methylmercuric chloride] results in decreased expression of FASN mRNA27814245
D008767Methylmercury CompoundsMethylmercury Compounds results in decreased expression of FASN mRNA16966085
D008741Methyl MethanesulfonateMethyl Methanesulfonate results in decreased expression of FASN mRNA23649840
D008769MethylnitronitrosoguanidineMethylnitronitrosoguanidine results in increased expression of FASN mRNA12634122
D008770MethylnitrosoureaMethylnitrosourea results in increased expression of FASN mRNA16525678
D0156551-Methyl-4-phenylpyridinium1-Methyl-4-phenylpyridinium results in decreased expression of FASN mRNA22776087
D015741MetriboloneMetribolone promotes the reaction [NDRG1 protein binds to FASN protein]17220478
D015741MetriboloneMetribolone results in increased expression of FASN protein17152098
D008798Mevalonic AcidMevalonic Acid inhibits the reaction [Atorvastatin Calcium results in increased expression of FASN mRNA]12056585
D015735MifepristoneMifepristone inhibits the reaction [Norethynodrel results in increased activity of FASN protein]15870863
D008942MitoxantroneFASN protein results in decreased susceptibility to Mitoxantrone18281512
D008942Mitoxantroneorlistat inhibits the reaction [FASN protein results in decreased susceptibility to Mitoxantrone]18281512
C016599mono-(2-ethylhexyl)phthalatemono-(2-ethylhexyl)phthalate results in increased expression of FASN mRNA23118965
C016599mono-(2-ethylhexyl)phthalate[Genistein co-treated with mono-(2-ethylhexyl)phthalate] results in increased expression of FASN mRNA27181934
C016599mono-(2-ethylhexyl)phthalatemono-(2-ethylhexyl)phthalate results in decreased expression of FASN mRNA25543134
C016599mono-(2-ethylhexyl)phthalatemono-(2-ethylhexyl)phthalate results in increased expression of FASN protein27384973
C437683motexafin gadoliniummotexafin gadolinium results in decreased expression of FASN mRNA16357179
C568376MT19c compoundMT19c compound results in decreased expression of FASN mRNA21781307
C583365N-(2-(1,1'-bicyclopropyl)-2-ylphenyl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide"N-(2-(1,1'-bicyclopropyl)-2-ylphenyl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide results in decreased expression of FASN mRNA"29244179
D009270NaloxoneNaloxone results in decreased expression of FASN mRNA17522070
D037742Nanotubes, Carbon"Nanotubes, Carbon results in increased expression of FASN mRNA"24389112
D037742Nanotubes, Carbon"Nanotubes, Carbon analog results in decreased expression of FASN mRNA"25620056
D037742Nanotubes, Carbon"Nanotubes, Carbon results in decreased expression of FASN mRNA"25620056
D0150581-Naphthylisothiocyanate[1-Naphthylisothiocyanate co-treated with Cholic Acids] affects the expression of FASN mRNA27344345
C005274naringinnaringin affects the reaction [LEPR protein affects the activity of FASN protein]16427799
C005274naringinnaringin inhibits the reaction [Dietary Fats results in increased expression of FASN mRNA]22198281
C461488N-benzylpiperazineN-benzylpiperazine results in increased expression of FASN mRNA26821219
C051752nefazodonenefazodone results in decreased expression of FASN mRNA24136188
D019888NelfinavirNelfinavir results in decreased expression of FASN mRNA21355074
D019888NelfinavirNelfinavir results in decreased expression of FASN protein21355074
D009525NiacinNiacin results in decreased expression of FASN mRNA19131065
D009532NickelNickel results in decreased expression of FASN mRNA24768652
D009532NickelNickel results in decreased expression of FASN mRNA12540486
C119536nickel acetatenickel acetate affects the expression of FASN mRNA23828170
C119536nickel acetatenickel acetate affects the expression of FASN protein23828170
C022838nickel chloridenickel chloride results in decreased expression of FASN mRNA17312168
C022838nickel chloridenickel chloride affects the expression of FASN mRNA22110744
C028007nickel monoxidenickel monoxide results in increased expression of FASN mRNA19167457
C029938nickel sulfatenickel sulfate results in increased expression of FASN mRNA16780908
C029938nickel sulfatenickel sulfate results in decreased expression of FASN mRNA16100012
D009538Nicotine"(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine inhibits the reaction [Nicotine results in decreased activity of FASN protein]"17635921
D009538Nicotine[Nicotine promotes the reaction [Peroxynitrous Acid results in increased activity of PRKAA2 protein]] which results in increased phosphorylation of FASN protein17635921
D009538Nicotine[[Nicotine promotes the reaction [Peroxynitrous Acid results in increased activity of PRKAA2 protein]] which results in increased phosphorylation of FASN protein] which results in decreased activity of FASN protein17635921
D009538NicotineNicotine results in decreased activity of FASN protein17635921
D009538Nicotine[Nicotine results in decreased activity of FASN protein] which results in increased phosphorylation of ACACA protein17635921
D009538Nicotine[Nicotine results in decreased activity of FASN protein] which results in increased phosphorylation of PRKAA2 protein17635921
D009538Nicotine[Nicotine results in increased activity of PRKAA2 protein] which results in decreased activity of FASN protein17635921
D009538NicotinePRKAA2 protein mutant form inhibits the reaction [Nicotine results in decreased activity of FASN protein]17635921
D009538NicotineNicotine promotes the reaction [NR1H3 protein binds to FASN promoter]24368177
D009538NicotineNicotine results in increased expression of FASN mRNA24368177|2915503
D009538NicotineNicotine results in increased expression of FASN protein24368177
D009538NicotineINS protein inhibits the reaction [Nicotine results in decreased activity of FASN protein]17635921
C012655nimesulidenimesulide results in decreased expression of FASN mRNA24136188
C002741N-nitrosomorpholineN-nitrosomorpholine results in increased expression of FASN mRNA15543204
C002741N-nitrosomorpholineN-nitrosomorpholine results in increased expression of FASN protein15543204
C025256nonylphenolnonylphenol results in increased expression of FASN mRNA26382854
D009640NorethindroneNorethindrone results in increased activity of FASN protein15870863
D009641Norethynodrelfulvestrant inhibits the reaction [Norethynodrel results in increased activity of FASN protein]15870863
D009641NorethynodrelMifepristone inhibits the reaction [Norethynodrel results in increased activity of FASN protein]15870863
D009641NorethynodrelNorethynodrel results in increased activity of and results in increased expression of FASN protein15870863
C028525N-phenylmaleimideN-phenylmaleimide analog results in decreased expression of FASN mRNA27507602
C028525N-phenylmaleimideN-phenylmaleimide results in decreased expression of FASN mRNA27507602
C475771N-piperidinyl-(8-chloro-1-(2,4-dichlorophenyl)-1,4,5,6-tetrahydrobenzo(6,7)cyclohepta(1,2-c)pyrazole-3-carboxamide)"N-piperidinyl-(8-chloro-1-(2,4-dichlorophenyl)-1,4,5,6-tetrahydrobenzo(6,7)cyclohepta(1,2-c)pyrazole-3-carboxamide) inhibits the reaction [bisphenol A results in increased expression of FASN mRNA]"27014939
C558013NSC 689534[NSC 689534 binds to Copper] which results in decreased expression of FASN mRNA20971185
C464660obeticholic acidobeticholic acid inhibits the reaction [Ethanol results in increased expression of FASN protein]27939985
C464660obeticholic acidobeticholic acid results in decreased expression of FASN mRNA27939613
C464660obeticholic acidobeticholic acid inhibits the reaction [Palmitic Acid results in increased expression of FASN mRNA]26655953
D019787Linoleic AcidLinoleic Acid results in decreased expression of FASN mRNA14563831
D019301Oleic Acid[Oleic Acid co-treated with Bezafibrate] results in increased expression of FASN mRNA24534255
D019301Oleic Acid[Oleic Acid co-treated with Fenofibrate] affects the expression of FASN mRNA24534255
D019301Oleic Acid[Sucrose co-treated with Oleic Acid] results in increased expression of FASN mRNA26895660
D019301Oleic Acid[Oleic Acid co-treated with Palmitic Acid] inhibits the reaction [Ethanol results in increased expression of FASN mRNA]26854922
D019301Oleic Acid[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of FASN mRNA26854922
C572462octaphlorethol Aoctaphlorethol A inhibits the reaction [LEPR gene mutant form results in increased expression of FASN mRNA]26939912
C076029olanzapineolanzapine results in increased expression of FASN mRNA17651982
C018620oleoresinsoleoresins results in increased expression of FASN mRNA20008804
C108709oleoyl-estrone[Corticosterone co-treated with oleoyl-estrone] affects the expression of FASN mRNA19545626
C108709oleoyl-estroneoleoyl-estrone results in decreased expression of FASN mRNA17725831|1932603
C002769oleuropein"oleuropein inhibits the reaction [Cholesterol, Dietary results in increased expression of FASN protein]"27019295
D000069463Olive OilOlive Oil inhibits the reaction [Dietary Fats results in decreased expression of FASN mRNA]24450870
D000068557Olmesartan MedoxomilOlmesartan Medoxomil results in decreased expression of FASN mRNA18501344
D015525Fatty Acids, Omega-3"Fatty Acids, Omega-3 results in decreased expression of FASN mRNA"23333450
D015525Fatty Acids, Omega-3"Fatty Acids, Omega-3 results in decreased expression of FASN protein"23333450
D015525Fatty Acids, Omega-3"NR1H2 gene mutant form inhibits the reaction [Fatty Acids, Omega-3 results in decreased expression of FASN protein]"23333450
D015525Fatty Acids, Omega-3"NR1H3 gene mutant form inhibits the reaction [Fatty Acids, Omega-3 results in decreased expression of FASN protein]"23333450
C055122orlistatFASN protein affects the susceptibility to orlistat15870086
C055122orlistatorlistat analog binds to FASN protein20577697
C055122orlistatorlistat analog results in decreased activity of FASN protein18710210
C055122orlistatorlistat binds to and results in decreased activity of FASN protein17618296|1784709
C055122orlistatorlistat inhibits the reaction [FASN protein results in decreased susceptibility to Doxorubicin]18281512
C055122orlistatorlistat inhibits the reaction [FASN protein results in decreased susceptibility to Mitoxantrone]18281512
C055122orlistatorlistat results in decreased activity of FASN protein15026345|1513827
C055122orlistat[orlistat results in decreased activity of FASN protein] which results in decreased abundance of Fatty Acids18723500
C055122orlistat[orlistat results in decreased activity of FASN protein] which results in decreased abundance of Phosphatidylcholines18723500
C055122orlistat[orlistat results in decreased activity of FASN protein] which results in decreased abundance of Phosphorylcholine18723500
C055122orlistat[orlistat results in decreased activity of FASN protein] which results in decreased chemical synthesis of Fatty Acids17012255
C055122orlistat[orlistat results in decreased activity of FASN protein] which results in decreased expression of SKP2 protein15138278
C055122orlistatorlistat inhibits the reaction [FASN protein results in increased chemical synthesis of Palmitic Acid]21213365
C055122orlistatorlistat results in decreased activity of FASN protein21213365
C055122orlistat"[orlistat results in decreased activity of FASN protein] which affects the abundance of Fatty Acids, Nonesterified"21213365
C055122orlistatorlistat results in decreased activity of FASN protein16986934|1728316
D010100OxygenEPAS1 gene mutant form inhibits the reaction [Oxygen deficiency results in decreased expression of FASN mRNA]24503013
D010100OxygenHIF1A gene mutant form inhibits the reaction [Oxygen deficiency results in decreased expression of FASN mRNA]24503013
D010100OxygenOxygen deficiency results in decreased expression of FASN mRNA24503013|2651600
D010100OxygenOxygen deficiency results in increased expression of FASN mRNA24205000
D010126OzoneOzone results in decreased expression of FASN mRNA16716893
D010168PalmitatesPalmitates binds to FASN protein17847090
D010168Palmitates[Sucrose co-treated with Palmitates] results in increased expression of FASN mRNA26895660
D010168Palmitates[Palmitates co-treated with TO-901317] results in increased expression of FASN mRNA21209018
D010168PalmitatesFASN protein results in increased chemical synthesis of Palmitates17283163
D019308Palmitic Acidobeticholic acid inhibits the reaction [Palmitic Acid results in increased expression of FASN mRNA]26655953
D019308Palmitic Acidorlistat inhibits the reaction [FASN protein results in increased chemical synthesis of Palmitic Acid]21213365
D019308Palmitic AcidPalmitic Acid results in increased expression of FASN mRNA26655953
D019308Palmitic Acid[Oleic Acid co-treated with Palmitic Acid] inhibits the reaction [Ethanol results in increased expression of FASN mRNA]26854922
D019308Palmitic Acid[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of FASN mRNA26854922
D019308Palmitic AcidFASN protein results in increased chemical synthesis of Palmitic Acid18281512|2080579
D019308Palmitic AcidPalmitic Acid results in increased expression of FASN mRNA22479612
D000073878Palm OilPalm Oil affects the expression of FASN mRNA19680557
D000073878Palm OilPalm Oil results in decreased expression of FASN mRNA18042831
C506614PD 0325901PD 0325901 inhibits the reaction [Protein Kinase Inhibitors inhibits the reaction [FASN protein results in increased expression of UCP1 protein]]26670611
D010400Penicillin G[Penicillin G co-treated with Erythromycin] results in increased expression of FASN mRNA27503388
D010400Penicillin GPenicillin G results in increased expression of FASN mRNA27503388
C033094perfluorobutyric acidperfluorobutyric acid analog results in increased expression of FASN mRNA21878386
C522391perfluorododecanoic acidperfluorododecanoic acid results in decreased expression of FASN mRNA23353032
C471071perfluorohexanesulfonic acidperfluorohexanesulfonic acid results in increased expression of FASN mRNA28049043
C076994perfluorooctane sulfonic acidperfluorooctane sulfonic acid results in decreased expression of FASN protein26178269
C076994perfluorooctane sulfonic acidperfluorooctane sulfonic acid results in increased expression of FASN protein28288859
C076994perfluorooctane sulfonic acidperfluorooctane sulfonic acid results in decreased expression of FASN mRNA19162173|2172336
C076994perfluorooctane sulfonic acidperfluorooctane sulfonic acid results in increased expression of FASN mRNA18692542
C023036perfluorooctanoic acidperfluorooctanoic acid results in increased expression of FASN mRNA25092180|2804904
C023036perfluorooctanoic acidperfluorooctanoic acid results in decreased expression of FASN mRNA19162173
D026023PermethrinPermethrin results in increased expression of FASN mRNA24911977
D030421Peroxynitrous Acid"(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine inhibits the reaction [Peroxynitrous Acid results in decreased activity of FASN protein]"17635921
D030421Peroxynitrous Acid[Nicotine promotes the reaction [Peroxynitrous Acid results in increased activity of PRKAA2 protein]] which results in increased phosphorylation of FASN protein17635921
D030421Peroxynitrous Acid[[Nicotine promotes the reaction [Peroxynitrous Acid results in increased activity of PRKAA2 protein]] which results in increased phosphorylation of FASN protein] which results in decreased activity of FASN protein17635921
D030421Peroxynitrous AcidPeroxynitrous Acid results in decreased activity of FASN protein17635921
D030421Peroxynitrous Acid[Peroxynitrous Acid results in increased activity of PRKAA2 protein] which results in decreased activity of FASN protein17635921
D030421Peroxynitrous AcidPRKAA2 protein mutant form inhibits the reaction [Peroxynitrous Acid results in decreased activity of FASN protein]17635921
D030421Peroxynitrous AcidINS protein inhibits the reaction [Peroxynitrous Acid results in decreased activity of FASN protein]17635921
D010578PetroleumPetroleum affects the expression of FASN mRNA25208076
D015232DinoprostoneDinoprostone promotes the reaction [Celecoxib results in decreased activity of FASN protein]19159447
C031181phenanthrenephenanthrene results in increased expression of FASN mRNA19457238
D010634PhenobarbitalPhenobarbital affects the expression of FASN mRNA23091169
D010654PhenylbutyratesPhenylbutyrates inhibits the reaction [Fructose results in increased expression of FASN mRNA]22698815
D010713Phosphatidylcholines[orlistat results in decreased activity of FASN protein] which results in decreased abundance of Phosphatidylcholines18723500
D010767Phosphorylcholine[Cerulenin results in decreased activity of FASN protein] which results in decreased abundance of Phosphorylcholine18723500
D010767Phosphorylcholine[orlistat results in decreased activity of FASN protein] which results in decreased abundance of Phosphorylcholine18723500
D010795Phthalic AcidsPhthalic Acids results in increased expression of FASN mRNA21061450
C006253pirinixic acidEthanol inhibits the reaction [pirinixic acid results in decreased expression of FASN mRNA]18620774
C006253pirinixic acidpirinixic acid results in decreased expression of FASN mRNA18620774|2381119
C006253pirinixic acidpirinixic acid results in increased expression of FASN mRNA15302862|1537516
C006253pirinixic acidPPARA protein affects the reaction [pirinixic acid results in increased expression of FASN mRNA]15777286
C006253pirinixic acidPPARA protein promotes the reaction [pirinixic acid results in increased expression of FASN mRNA]20059764
C006253pirinixic acid[[[pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased localization of and results in decreased activity of SREBF1 protein] which results in decreased expression of FASN mRNA] which results in decreased abundance of Triglycerides19248225
C006253pirinixic acidpirinixic acid results in increased expression of FASN mRNA19162173
D010936Plant ExtractsPlant Extracts binds to and results in decreased activity of FASN protein24341420
D010936Plant ExtractsPlant Extracts affects the expression of FASN mRNA25086370
D010936Plant ExtractsPlant Extracts inhibits the reaction [Dietary Fats results in increased expression of FASN mRNA]22967722
D010936Plant ExtractsPlant Extracts results in decreased expression of FASN mRNA23810795
D010936Plant ExtractsPlant Extracts results in decreased expression of FASN protein22967722
D010936Plant ExtractsPlant Extracts inhibits the reaction [Dietary Fats results in increased expression of FASN mRNA]23365609
D010936Plant ExtractsPlant Extracts inhibits the reaction [Dietary Fats results in increased expression of FASN protein]23026700
D010936Plant ExtractsPlant Extracts results in decreased expression of FASN mRNA23684756
D028321Plant Preparations[Plant Preparations co-treated with Dietary Fats] affects the expression of FASN mRNA25861419
D028321Plant PreparationsPlant Preparations inhibits the reaction [Fructose results in increased expression of FASN protein]27531227
D028321Plant Preparations"Plant Preparations inhibits the reaction [Cholesterol, Dietary results in increased expression of FASN mRNA]"22579924
D011084Polycyclic Aromatic HydrocarbonsPolycyclic Aromatic Hydrocarbons results in increased expression of FASN mRNA25347678
D011192Potassium DichromatePotassium Dichromate results in increased expression of FASN protein23718831
D045542PQQ CofactorPQQ Cofactor results in decreased expression of FASN mRNA25843018
D011285Pregnenolone CarbonitrilePregnenolone Carbonitrile inhibits the reaction [Lithocholic Acid results in decreased expression of FASN mRNA]20359477
D011285Pregnenolone CarbonitrilePregnenolone Carbonitrile results in increased expression of FASN mRNA20359477
D011285Pregnenolone CarbonitrilePregnenolone Carbonitrile results in decreased expression of FASN mRNA19162173
C045362prochlorazprochloraz results in increased expression of FASN mRNA21470553
C045950propiconazolepropiconazole results in decreased expression of FASN mRNA23339182
C015586propiverinepropiverine binds to FASN protein29273565
C006068propylparabenpropylparaben results in increased expression of FASN mRNA22956630
D047428Protein Kinase InhibitorsPD 0325901 inhibits the reaction [Protein Kinase Inhibitors inhibits the reaction [FASN protein results in increased expression of UCP1 protein]]26670611
D047428Protein Kinase InhibitorsProtein Kinase Inhibitors inhibits the reaction [FASN protein affects the localization of ARRB1 protein]26670611
D047428Protein Kinase InhibitorsProtein Kinase Inhibitors inhibits the reaction [FASN protein results in decreased abundance of Adenosine Triphosphate]26670611
D047428Protein Kinase Inhibitors"Protein Kinase Inhibitors inhibits the reaction [FASN protein results in increased abundance of Fatty Acids, Nonesterified]"26670611
D047428Protein Kinase InhibitorsProtein Kinase Inhibitors inhibits the reaction [FASN protein results in increased abundance of Triglycerides]26670611
D047428Protein Kinase InhibitorsProtein Kinase Inhibitors inhibits the reaction [FASN protein results in increased expression of ACACA mRNA]26670611
D047428Protein Kinase InhibitorsProtein Kinase Inhibitors inhibits the reaction [FASN protein results in increased expression of ADIPOQ mRNA]26670611
D047428Protein Kinase InhibitorsProtein Kinase Inhibitors inhibits the reaction [FASN protein results in increased expression of FASN protein]26670611
D047428Protein Kinase InhibitorsProtein Kinase Inhibitors inhibits the reaction [FASN protein results in increased expression of RETN mRNA]26670611
D047428Protein Kinase InhibitorsProtein Kinase Inhibitors inhibits the reaction [FASN protein results in increased expression of UCP1 mRNA]26670611
D047428Protein Kinase InhibitorsProtein Kinase Inhibitors inhibits the reaction [FASN protein results in increased expression of UCP1 protein]26670611
D047428Protein Kinase InhibitorsProtein Kinase Inhibitors results in decreased expression of FASN protein26670611
C107773pterostilbene[Dietary Sucrose co-treated with Dietary Fats co-treated with pterostilbene] affects the activity of FASN protein25083823
C496788PX-866PX-866 promotes the reaction [SORT1 protein results in decreased expression of FASN mRNA]25805502
C513428pyrachlostrobinpyrachlostrobin results in decreased expression of FASN mRNA29127035
D011794QuercetinQuercetin inhibits the reaction [[Fatty Acids co-treated with INS protein] results in increased expression of FASN mRNA]24648896
D011794QuercetinQuercetin inhibits the reaction [[Fatty Acids co-treated with INS protein] results in increased expression of FASN protein]24648896
D011794QuercetinQuercetin inhibits the reaction [Glucose results in increased expression of FASN protein]23647015
D011794QuercetinQuercetin results in decreased expression of FASN mRNA19729006|2059680
D011794QuercetinQuercetin results in increased expression of FASN protein19207037
D011794Quercetin[Quercetin co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in decreased expression of FASN protein18586010
D011794QuercetinQuercetin inhibits the reaction [[Dietary Fats co-treated with Dietary Sucrose] results in increased expression of FASN mRNA]21462320
D011794QuercetinQuercetin inhibits the reaction [Dietary Fats results in increased expression of FASN mRNA]22447684|2402568
D011794QuercetinQuercetin inhibits the reaction [Dietary Fats results in increased expression of FASN protein]22447684
D011794QuercetinQuercetin results in decreased activity of FASN protein17032037
D011794QuercetinQuercetin results in decreased expression of FASN mRNA17032037
D011794QuercetinQuercetin inhibits the reaction [Glucose results in increased expression of FASN protein]23647015
D011794QuercetinQuercetin inhibits the reaction [Streptozocin results in increased expression of FASN mRNA]23647015
D011794QuercetinQuercetin inhibits the reaction [Streptozocin results in increased expression of FASN protein]23647015
C502851quinocetonequinocetone results in increased expression of FASN mRNA27046791
C059514resveratrolresveratrol results in decreased expression of FASN mRNA25866375
C059514resveratrolresveratrol binds to and results in decreased activity of FASN protein24341420
C059514resveratrolresveratrol inhibits the reaction [TO-901317 results in increased expression of FASN mRNA]23651738
C059514resveratrolresveratrol results in decreased expression of FASN mRNA20878097
C059514resveratrolresveratrol results in decreased expression of FASN protein25448084
C059514resveratrol[resveratrol results in increased activity of SIRT1 protein] inhibits the reaction [[Glucose results in increased expression of FASN protein] which results in increased abundance of Triglycerides]18482975
C059514resveratrolresveratrol inhibits the reaction [Ethanol results in increased expression of FASN mRNA]18755807
C059514resveratrolresveratrol results in decreased expression of FASN mRNA18755807|1893033
C059514resveratrol[resveratrol results in decreased expression of SREBF1 mRNA] which results in decreased expression of FASN mRNA22659145
C059514resveratrol"(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine inhibits the reaction [resveratrol metabolite inhibits the reaction [TO-901317 results in increased expression of FASN mRNA]]"24633463
C059514resveratrol[Fenofibrate co-treated with resveratrol] inhibits the reaction [Fructose results in increased expression of FASN mRNA]26973390
C059514resveratrolresveratrol inhibits the reaction [Fructose results in increased expression of FASN mRNA]26973390
C059514resveratrolresveratrol inhibits the reaction [High Fructose Corn Syrup results in increased expression of FASN mRNA]25238689
C059514resveratrolresveratrol inhibits the reaction [INS1 protein results in increased expression of FASN mRNA]16626303
C059514resveratrolresveratrol metabolite inhibits the reaction [TO-901317 results in increased expression of FASN mRNA]24633463
C059514resveratrolresveratrol results in decreased expression of FASN mRNA16626303
C499731resveratrol-4'-O-glucuronideresveratrol-4'-O-glucuronide results in decreased expression of FASN mRNA22945685
D015474IsotretinoinIsotretinoin results in decreased expression of FASN mRNA15982314|2043688
D012293RifampinRifampin results in increased expression of FASN mRNA27806127
C089032rimonabantrimonabant inhibits the reaction [Dietary Fats results in decreased expression of FASN mRNA]19030233
C089032rimonabantrimonabant results in decreased expression of FASN mRNA20110567
D019438RitonavirRitonavir affects the expression of FASN mRNA17719200
C089730rosiglitazoneFASN protein promotes the reaction [rosiglitazone promotes the reaction [PPARG protein results in decreased abundance of Adenosine Triphosphate]]26670611
C089730rosiglitazone"FASN protein promotes the reaction [rosiglitazone promotes the reaction [PPARG protein results in increased abundance of Fatty Acids, Nonesterified]]"26670611
C089730rosiglitazoneFASN protein results in increased susceptibility to rosiglitazone26670611
C089730rosiglitazonerosiglitazone promotes the reaction [PPARG protein results in increased expression of FASN protein]26670611
C089730rosiglitazonerosiglitazone results in increased expression of FASN mRNA16806087|1714856
C089730rosiglitazonerosiglitazone affects the expression of FASN mRNA22013433
C089730rosiglitazonerosiglitazone inhibits the reaction [Ethanol results in decreased expression of FASN mRNA]22173916
C089730rosiglitazonerosiglitazone results in decreased expression of FASN mRNA17245590
C089730rosiglitazonerosiglitazone results in increased expression of FASN mRNA23322813|2667061
C089730rosiglitazonerosiglitazone results in increased expression of FASN protein26670611
C089730rosiglitazoneUCP1 protein promotes the reaction [rosiglitazone results in increased expression of FASN protein]26670611
C089730rosiglitazonerosiglitazone inhibits the reaction [Fructose results in increased expression of FASN mRNA]19196556
C089730rosiglitazonerosiglitazone results in increased expression of FASN mRNA21515302
C089730rosiglitazonerosiglitazone results in increased expression of FASN protein26670611
D012402RotenoneRotenone results in decreased expression of FASN mRNA19013527|1969370
C513635S-2-pentyl-4-pentynoic hydroxamic acidS-2-pentyl-4-pentynoic hydroxamic acid results in decreased expression of FASN mRNA21427059
C513635S-2-pentyl-4-pentynoic hydroxamic acidS-2-pentyl-4-pentynoic hydroxamic acid results in increased expression of FASN mRNA21427059
C065299S-allylcysteine"S-allylcysteine inhibits the reaction [Fatty Acids, Nonesterified results in increased expression of FASN mRNA]"23465592
D012503SaponinsSaponins results in decreased expression of FASN mRNA27369806
D012603ScopoletinScopoletin inhibits the reaction [Ethanol results in increased expression of FASN mRNA]26115886
D012643SeleniumSelenium results in increased expression of FASN mRNA19244175
D012643SeleniumSelenium results in increased expression of FASN mRNA19022953
D000068677Sildenafil CitrateSildenafil Citrate results in increased expression of FASN mRNA20471953
D012822Silicon DioxideSilicon Dioxide analog affects the secretion of FASN protein25895662
D012822Silicon DioxideSilicon Dioxide results in increased activity of FASN protein1647683
C440975silybinsilybin inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of FASN protein]25559859
D012838SilymarinSilymarin inhibits the reaction [Ethanol results in increased expression of FASN mRNA]26115886
D019821SimvastatinSimvastatin results in increased expression of FASN mRNA11728391
D019821SimvastatinSimvastatin results in increased expression of FASN mRNA12056585
C017947sodium arsenitesodium arsenite affects the expression of FASN25367288
C016104sodium bichromatesodium bichromate results in decreased expression of FASN mRNA25993096
C538809sodium pentaboratesodium pentaborate inhibits the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased expression of FASN mRNA]28285642
D018038Sodium SeleniteSodium Selenite inhibits the reaction [Copper Sulfate results in decreased expression of FASN mRNA]24854705
D053260SootSoot results in increased expression of FASN mRNA26551751
C012042steviolsteviol affects the reaction [[LEP protein co-treated with LDLR protein] affects the expression of FASN mRNA]25554529
D013311Streptozocin[Dietary Fats co-treated with Streptozocin] results in decreased expression of FASN mRNA27769711
D013311Streptozocinesculetin promotes the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of FASN mRNA]27769711
D013311StreptozocinAllopurinol inhibits the reaction [Streptozocin results in increased expression of FASN mRNA]23647015
D013311StreptozocinAllopurinol inhibits the reaction [Streptozocin results in increased expression of FASN protein]23647015
D013311StreptozocinGHRL protein promotes the reaction [Streptozocin results in decreased expression of FASN mRNA]20219977
D013311StreptozocinINS protein inhibits the reaction [Streptozocin results in decreased expression of FASN mRNA]20219977
D013311StreptozocinQuercetin inhibits the reaction [Streptozocin results in increased expression of FASN mRNA]23647015
D013311StreptozocinQuercetin inhibits the reaction [Streptozocin results in increased expression of FASN protein]23647015
D013311StreptozocinStreptozocin results in decreased expression of FASN mRNA20219977
D013311StreptozocinStreptozocin results in increased expression of FASN mRNA23647015
D013311StreptozocinStreptozocin results in increased expression of FASN protein23647015
D013395Sucrose[Sucrose co-treated with Oleic Acid] results in increased expression of FASN mRNA26895660
D013395Sucrose[Sucrose co-treated with Palmitates] results in increased expression of FASN mRNA26895660
C016766sulforafan[sulforafan co-treated with Aflatoxin B1] affects the expression of FASN mRNA25450479
D000952Antigens, Polyomavirus Transforming"Antigens, Polyomavirus Transforming results in decreased expression of FASN mRNA"26680231
D014284TriiodothyronineTriiodothyronine results in increased expression of FASN mRNA15953391
C013698tallowtallow affects the expression of FASN mRNA19680557
D013629TamoxifenTamoxifen results in decreased expression of FASN mRNA25123088
D013629TamoxifenTamoxifen results in increased expression of FASN mRNA23038002
D013629Tamoxifen[Tamoxifen co-treated with bexarotene] results in increased expression of FASN mRNA17630414
D013629TamoxifenTamoxifen results in decreased expression of FASN mRNA17630414|1922454
D013629TamoxifenTamoxifen results in increased expression of FASN mRNA17630414
C030141taurine-ursodeoxycholate conjugatetaurine-ursodeoxycholate conjugate inhibits the reaction [LEP gene mutant form results in increased expression of FASN mRNA]21079772
D013662TeaTea inhibits the reaction [Fructose results in increased expression of FASN mRNA]19193814
C020806tetrabromobisphenol Atetrabromobisphenol A results in increased expression of FASN mRNA27914987
D013749Tetrachlorodibenzodioxin"2,4,5,2',4',5'-hexachlorobiphenyl promotes the reaction [Tetrachlorodibenzodioxin results in decreased expression of FASN mRNA]"21851831
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of FASN mRNA26377647|2892240
D013749Tetrachlorodibenzodioxin"[Tetrachlorodibenzodioxin co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Diethylhexyl Phthalate co-treated with bisphenol A] results in decreased expression of FASN mRNA"28433925
D013749Tetrachlorodibenzodioxin[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in decreased expression of FASN mRNA17942748
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin inhibits the reaction [Dietary Fats results in increased expression of FASN mRNA]27713108
D013749Tetrachlorodibenzodioxin"Tetrachlorodibenzodioxin promotes the reaction [2,4,5,2',4',5'-hexachlorobiphenyl results in decreased expression of FASN mRNA]"21851831
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased expression of FASN mRNA15800033|1696003
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of FASN mRNA21846477
D013749TetrachlorodibenzodioxinTIPARP protein inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of FASN mRNA]25975270
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased expression of FASN mRNA16054898|1696003
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased expression of FASN protein16548065
D013752TetracyclineTetracycline results in decreased expression of FASN mRNA17522070|1922454
D045162ThiazolidinedionesThiazolidinediones results in decreased expression of FASN mRNA21870829
D013849ThimerosalThimerosal results in decreased expression of FASN mRNA27188386
D013853Thioacetamide[Diethylnitrosamine co-treated with Thioacetamide] results in decreased expression of FASN mRNA28943392
D013853ThioacetamideThioacetamide results in decreased expression of FASN mRNA23411599
D013882Thiosemicarbazones[Thiosemicarbazones binds to Copper] which results in increased expression of FASN protein20931265
C055421tin mesoporphyrintin mesoporphyrin inhibits the reaction [cobaltiprotoporphyrin inhibits the reaction [LEP gene mutant form results in increased expression of FASN protein]]23839791
C009495titanium dioxidetitanium dioxide results in decreased expression of FASN mRNA23557971
C423915TO-901317atheronal-A inhibits the reaction [TO-901317 results in increased expression of FASN mRNA]27703007
C423915TO-901317resveratrol inhibits the reaction [TO-901317 results in increased expression of FASN mRNA]23651738
C423915TO-901317TO-901317 results in decreased expression of FASN mRNA28903485
C423915TO-901317TO-901317 results in increased expression of FASN mRNA15548517|2365173
C423915TO-901317TO-901317 results in increased expression of FASN protein28903485
C423915TO-901317[Fructose co-treated with Dietary Fats co-treated with TO-901317] results in increased expression of FASN mRNA19509184
C423915TO-901317NR1H2 gene mutant form inhibits the reaction [TO-901317 results in increased expression of FASN mRNA]23063693|2333345
C423915TO-901317NR1H3 gene mutant form inhibits the reaction [TO-901317 results in increased expression of FASN mRNA]23063693|2333345
C423915TO-901317TO-901317 results in increased expression of FASN mRNA15302862|2306369
C423915TO-901317"(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine inhibits the reaction [resveratrol metabolite inhibits the reaction [TO-901317 results in increased expression of FASN mRNA]]"24633463
C423915TO-901317[Palmitates co-treated with TO-901317] results in increased expression of FASN mRNA21209018
C423915TO-901317resveratrol metabolite inhibits the reaction [TO-901317 results in increased expression of FASN mRNA]24633463
C423915TO-901317TO-901317 results in increased expression of FASN mRNA24633463
D014028Tobacco Smoke PollutionTobacco Smoke Pollution results in decreased expression of FASN mRNA28065790
C496197trans-10,cis-12-conjugated linoleic acid"trans-10,cis-12-conjugated linoleic acid results in decreased expression of FASN mRNA"16988111
C496197trans-10,cis-12-conjugated linoleic acid"trans-10,cis-12-conjugated linoleic acid results in increased expression of FASN mRNA"17217560
C495469trans-3-(4'-hydroxyphenyl)-2-propenoic acidtrans-3-(4'-hydroxyphenyl)-2-propenoic acid results in decreased expression of FASN mRNA21870829
D014212TretinoinTretinoin metabolite results in increased expression of FASN mRNA15982314
D014212TretinoinTretinoin results in decreased expression of FASN mRNA15982314|2372400
C011559tributyltintributyltin results in increased expression of FASN mRNA28011154
C011559tributyltintributyltin results in increased expression of FASN mRNA23322813
D014241TrichloroethyleneTrichloroethylene results in increased expression of FASN mRNA19254012|1944899
D014260TriclosanTriclosan results in decreased activity of FASN protein15707987
D014260TriclosanTriclosan results in decreased expression of FASN mRNA15707987
D014260TriclosanTriclosan results in decreased activity of FASN protein15358634
D014280TriglyceridesFASN protein results in increased abundance of Triglycerides26670611
D014280Triglycerides[Glucose results in increased expression of FASN protein] which results in increased abundance of Triglycerides18482975
D014280TriglyceridesProtein Kinase Inhibitors inhibits the reaction [FASN protein results in increased abundance of Triglycerides]26670611
D014280Triglycerides[resveratrol results in increased activity of SIRT1 protein] inhibits the reaction [[Glucose results in increased expression of FASN protein] which results in increased abundance of Triglycerides]18482975
D014280Triglycerides[[[pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased localization of and results in decreased activity of SREBF1 protein] which results in decreased expression of FASN mRNA] which results in decreased abundance of Triglycerides19248225
D014280Triglycerides[[[troglitazone binds to and results in increased activity of PPARG protein] which results in decreased localization of and results in decreased activity of SREBF1 protein] which results in decreased expression of FASN mRNA] which results in decreased abundance of Triglycerides19248225
D014304TrioleinTriolein inhibits the reaction [SCD1 gene mutant form inhibits the reaction [Fructose results in increased expression of FASN mRNA]]15066988
D014304TrioleinTriolein promotes the reaction [Fructose results in increased expression of FASN mRNA]15066988
C005445triphenyl phosphatetriphenyl phosphate results in increased expression of FASN mRNA28934090
C005445triphenyl phosphatetriphenyl phosphate results in increased expression of FASN mRNA28163246
C057693troglitazonetroglitazone results in increased expression of FASN mRNA19022234
C057693troglitazone[[[troglitazone binds to and results in increased activity of PPARG protein] which results in decreased localization of and results in decreased activity of SREBF1 protein] which results in decreased expression of FASN mRNA] which results in decreased abundance of Triglycerides19248225
C057693troglitazonetroglitazone results in decreased expression of FASN mRNA19022234
C057693troglitazone[troglitazone co-treated with TNF protein] results in decreased expression of FASN mRNA12732648
C057693troglitazonetroglitazone inhibits the reaction [INS protein results in increased expression of FASN protein]11919653
C057693troglitazonetroglitazone promotes the reaction [INS protein results in increased expression of FASN mRNA]11919653
C057693troglitazonetroglitazone promotes the reaction [INS protein results in increased expression of FASN protein]11919653
C080163trovafloxacin"[trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of FASN mRNA"18930950
C080163trovafloxacintrovafloxacin results in decreased expression of FASN mRNA24136188
D014415TunicamycinTunicamycin results in decreased expression of FASN mRNA22378314
D014415TunicamycinTunicamycin results in increased expression of FASN mRNA22414386
C112106UAB 30UAB 30 results in increased expression of FASN mRNA23292798
D014520UrethaneUrethane results in increased expression of FASN protein18413838
D014580Ursodeoxycholic AcidUrsodeoxycholic Acid results in decreased expression of FASN mRNA24312631
D014580Ursodeoxycholic AcidUrsodeoxycholic Acid results in decreased expression of FASN mRNA15885361
C406224valdecoxibvaldecoxib results in decreased expression of FASN mRNA24136188
C054478valilactonevalilactone results in decreased activity of FASN protein18710210
C054478valilactonevalilactone results in decreased activity of FASN protein16986934
D014635Valproic Acid"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of FASN mRNA"27188386
D014635Valproic AcidValproic Acid results in decreased expression of FASN mRNA23179753|2627250
D014635Valproic AcidValproic Acid results in increased expression of FASN protein25716160
D014635Valproic AcidValproic Acid affects the expression of FASN mRNA17292431
D014635Valproic AcidValproic Acid results in decreased expression of FASN mRNA19136453|2142705
D014635Valproic AcidValproic Acid results in increased expression of FASN mRNA15345369|2142705
D014635Valproic AcidValproic Acid results in decreased expression of FASN mRNA19224547
D001335Vehicle EmissionsVehicle Emissions affects the expression of FASN mRNA29175182
D001335Vehicle EmissionsVehicle Emissions results in increased expression of FASN protein29175182
D001335Vehicle EmissionsVehicle Emissions results in increased methylation of FASN gene25560391
D014805Vitamin B 12[Choline co-treated with Betaine co-treated with Vitamin B 12 co-treated with Folic Acid] affects the reaction [[Dietary Fats co-treated with Dietary Sucrose] affects the methylation of FASN promoter]22648174
C111237vorinostatvorinostat results in decreased expression of FASN mRNA27188386
D014874Water Pollutants, Chemical"Water Pollutants, Chemical affects the expression of FASN mRNA"25208076
D015016Yohimbine[Caffeine co-treated with coclaurine co-treated with aegeline co-treated with higenamine co-treated with Yohimbine co-treated with Hydrolyzable Tannins] results in decreased expression of FASN mRNA28843594
C403304zerumbonezerumbone inhibits the reaction [Dietary Fats results in increased expression of FASN mRNA]24709573
D015215ZidovudineZidovudine affects the expression of FASN mRNA20032539
D015215Zidovudine[Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of FASN mRNA11741158
D015215Zidovudine[Zidovudine co-treated with Lamivudine] results in increased expression of FASN mRNA11741158
D015215ZidovudineZidovudine results in decreased expression of FASN protein15722030
D015032ZincZinc results in decreased activity of FASN protein26602879
D015032ZincZinc results in decreased expression of FASN mRNA26602879
D015032ZincZinc affects the activity of FASN protein17181878
D019345Zinc AcetateZinc Acetate results in decreased expression of FASN mRNA16357179
C016837zinc chloridezinc chloride results in decreased expression of FASN mRNA21540303
D015034Zinc OxideZinc Oxide affects the expression of FASN mRNA28648595
D015034Zinc OxideZinc Oxide affects the expression of FASN protein28648595

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0003723RNA binding-HDA22658674  22681889  
GO:0004312fatty acid synthase activity-TAS-  
GO:0004313[acyl-carrier-protein] S-acetyltransferase activity-IEA-  
GO:0004314[acyl-carrier-protein] S-malonyltransferase activity-IEA-  
GO:00043153-oxoacyl-[acyl-carrier-protein] synthase activity-IEA-  
GO:00043163-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity-IEA-  
GO:0004320oleoyl-[acyl-carrier-protein] hydrolase activity-IEA-  
GO:0005515protein binding-IPI18022563  23427160  27478939  
GO:0008144drug binding-IEA-  
GO:0016295myristoyl-[acyl-carrier-protein] hydrolase activity-IEA-  
GO:0016296palmitoyl-[acyl-carrier-protein] hydrolase activity-IEA-  
GO:0031177phosphopantetheine binding-IEA-  
GO:0042803protein homodimerization activity-IEA-  
GO:0045296cadherin binding-HDA25468996  
GO:0047117enoyl-[acyl-carrier-protein] reductase (NADPH, A-specific) activity-IEA-  
GO:00474513-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity-IEA-  
GO:0070402NADPH binding-IEA-  
GO:01021313-oxo-glutaryl-[acp] methyl ester reductase activity-IEA-  
GO:01021323-oxo-pimeloyl-[acp] methyl ester reductase activity-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO:0001649osteoblast differentiation-HDA16210410  
GO:0006084acetyl-CoA metabolic process-IEA-  
GO:0006631fatty acid metabolic process-TAS7835891  
GO:0006633fatty acid biosynthetic process-IEA-  
GO:0030879mammary gland development-IEA-  
GO:0031325positive regulation of cellular metabolic process-TAS-  
GO:0045540regulation of cholesterol biosynthetic process-TAS-  
GO:0046949fatty-acyl-CoA biosynthetic process-TAS-  
GO:0055114oxidation-reduction process-IEA-  
GO:0071353cellular response to interleukin-4-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO:0005794Golgi apparatus-IDA-  
GO:0005829cytosol-IDA-  
GO:0005829cytosol-TAS-  
GO:0005886plasma membrane-IDA-  
GO:0016020membrane-HDA16210410  19946888  
GO:0042470melanosome-IEA-  
GO:0042587glycogen granule-IEA-  
GO:0070062extracellular exosome-HDA19056867  20458337  23533145  
KEGG ID KEGG Term
hsa00061Fatty acid biosynthesis
hsa01100Metabolic pathways
hsa04910Insulin signaling pathway
Reactome ID Reactome Term Evidence
R-HSA-1430728MetabolismTAS
R-HSA-1430728MetabolismIEA
R-HSA-163685Integration of energy metabolismTAS
R-HSA-163765ChREBP activates metabolic gene expressionTAS
R-HSA-1655829Regulation of cholesterol biosynthesis by SREBP (SREBF)TAS
R-HSA-196849Metabolism of water-soluble vitamins and cofactorsTAS
R-HSA-196854Metabolism of vitamins and cofactorsTAS
R-HSA-199220Vitamin B5 (pantothenate) metabolismTAS
R-HSA-2426168Activation of gene expression by SREBF (SREBP)TAS
R-HSA-556833Metabolism of lipidsTAS
R-HSA-556833Metabolism of lipidsIEA
R-HSA-75105Fatty acyl-CoA biosynthesisTAS
R-HSA-75105Fatty acyl-CoA biosynthesisIEA
R-HSA-8957322Metabolism of steroidsTAS
R-HSA-8978868Fatty acid metabolismTAS
R-HSA-8978868Fatty acid metabolismIEA

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
23989197Blood levels of saturated and monounsaturated fatty acids as markers of de novo lipogenesis and risk of prostate cancer. (2013 Oct 15)Chavarro JEAm J Epidemiol
20604875ErbB receptors and fatty acid synthase expression in aggressive head and neck squamous cell carcinomas. (2010 Nov)Silva SDOral Dis
20507599Epigenomic diversity of colorectal cancer indicated by LINE-1 methylation in a database of 869 tumors. (2010 May 27)Baba YMol Cancer