Gene: FAU

2197
FAU1|Fub1|Fubi|MNSFbeta|RPS30|S30|asr1
FAU, ubiquitin like and ribosomal protein S30 fusion
protein-coding
11q13.1
Ensembl:ENSG00000149806 MIM:134690 Vega:OTTHUMG00000165606 UniprotKB:P35544
NC_000011.10
PubMed
OD
1   
NA (AD)  NA (ND)   (Frontal_Cortex)
9.138e-1 (AD)  7.980e-1 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
RPL360.981
RPLP20.98
RPL13A0.979
RPL350.979
RPL80.977
RPS150.977
RPS100.977
RPL270.976
RPL190.976
RPS140.975

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
OR4F29-0.821
OR4F5-0.785
PCDHAC1-0.196
IL1RAPL2-0.189
PP2D1-0.189
STARD4-AS1-0.188
PPM1E-0.187
MCHR2-0.184
KCNH5-0.184
OR14I1-0.184

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C0163923,3'-diindolylmethane"3,3'-diindolylmethane promotes the reaction [Estradiol results in decreased expression of FAU mRNA]"11179685
C0095054,4'-diaminodiphenylmethane"4,4'-diaminodiphenylmethane results in decreased expression of FAU mRNA"18648102
D000082AcetaminophenAcetaminophen affects the expression of FAU mRNA17562736
D020106AcrylamideAcrylamide results in decreased expression of FAU mRNA28959563
D000517alpha-Chlorohydrinalpha-Chlorohydrin results in decreased expression of FAU mRNA28522335
D000643Ammonium ChlorideAmmonium Chloride affects the expression of FAU mRNA16483693
C015001arseniteFAU protein results in decreased susceptibility to arsenite10069470
D001564Benzo(a)pyreneAHR protein affects the reaction [Benzo(a)pyrene affects the expression of FAU mRNA]22228805
D001564Benzo(a)pyreneBenzo(a)pyrene results in decreased expression of FAU mRNA27195522
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of FAU mRNA22228805
D004958Estradiol"3,3'-diindolylmethane promotes the reaction [Estradiol results in decreased expression of FAU mRNA]"11179685
D004958EstradiolEstradiol results in decreased expression of FAU mRNA11179685
D004958EstradiolTetrachlorodibenzodioxin promotes the reaction [Estradiol results in decreased expression of FAU mRNA]11179685
C006780bisphenol Abisphenol A affects the expression of FAU mRNA25181051
D019256Cadmium Chloride[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of FAU mRNA19840844
D019256Cadmium ChlorideCadmium Chloride results in decreased expression of FAU mRNA18636176
C100187chloropicrinchloropicrin results in increased expression of FAU mRNA26352163
D002994ClofibrateClofibrate results in increased expression of FAU mRNA15033592
D003520CyclophosphamideCyclophosphamide results in increased expression of FAU mRNA11599041
D016572CyclosporineCyclosporine results in increased expression of FAU mRNA20106945
D004791Enzyme Inhibitors[Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation of FAU protein23301498
D004997Ethinyl Estradiol[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of FAU mRNA17942748
C040029gabapentin[gabapentin co-treated with Pentylenetetrazole] affects the expression of FAU mRNA21503142
D005947Glucose[INS protein co-treated with Glucose] results in decreased expression of FAU mRNA22634610
C031927hydroquinoneFAU protein results in decreased susceptibility to hydroquinone20025857
D018817N-Methyl-3,4-methylenedioxyamphetamine"N-Methyl-3,4-methylenedioxyamphetamine results in decreased expression of FAU mRNA"20188158
D008769Methylnitronitrosoguanidine[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of FAU mRNA19840844
D008769Methylnitronitrosoguanidine[Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of FAU mRNA19840844
D008769Methylnitronitrosoguanidine[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of FAU mRNA19840844
D019319Okadaic Acid[Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of FAU mRNA19840844
D010433Pentylenetetrazole[gabapentin co-treated with Pentylenetetrazole] affects the expression of FAU mRNA21503142
C023036perfluorooctanoic acidperfluorooctanoic acid results in increased expression of FAU mRNA19162173
D010575PesticidesPesticides results in increased methylation of FAU gene28396702
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin promotes the reaction [Estradiol results in decreased expression of FAU mRNA]11179685
D013749Tetrachlorodibenzodioxin[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of FAU mRNA17942748
D013755Tetradecanoylphorbol Acetate[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of FAU mRNA19840844
C013320tris(2-butoxyethyl) phosphatetris(2-butoxyethyl) phosphate results in increased expression of FAU mRNA29024780
D014635Valproic AcidValproic Acid results in increased methylation of FAU gene29154799
D001335Vehicle EmissionsVehicle Emissions results in increased methylation of FAU gene25560391
D015032ZincZinc deficiency results in decreased expression of FAU mRNA22171008

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0003723RNA binding-HDA22681889  
GO:0005515protein binding-IPI15677445  
GO ID GO Term Qualifier Evidence PubMed
GO:0008150biological_process-ND-  
GO ID GO Term Qualifier Evidence PubMed
GO:0005575cellular_component-ND-  
KEGG ID KEGG Term
hsa03010Ribosome
Reactome ID Reactome Term Evidence

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
28300812[A pharmacogenetic analysis of dopaminergic and opioidergic genes in opioid addicts treated with the combination of naltrexone and guanfacine]. (2016)Kibitov capital A, Cyrilliccapital O, CyrillicZh Nevrol Psikhiatr Im S S Korsakova