Gene info: ID 222171

Probe	Locus(GRCh37)	Gene	p-val	Trait	PubMed ID
cg18451588	chr7:29606289	PRR15	9.300e-18	Smoking	27651444
cg10580293	chr7:29605897	PRR15	2.100e-15	Smoking	27651444
cg06868100	chr7:29606349	PRR15	1.700e-14	Smoking	27651444
cg08900404	chr7:29605808	PRR15	3.400e-10	Smoking	27651444
cg23363754	chr7:29606082	PRR15	1.000e-9	Smoking	27651444
cg09635954	chr7:29605624	PRR15	2.000e-9	Smoking	27651444

Gene Symbol	Pearson Correlation Coefficient
OLFML2B	0.618
GLRX	0.532
TIFA	0.531
PLEKHA8P1	0.515
UHRF2	0.51
GPRIN3	0.509
FAM43A	0.508
DPP4	0.502
PLXDC2	0.501
SHB	0.5

Gene Symbol	Pearson Correlation Coefficient
PON1	-0.421
MRO	-0.417
ALDH1L1-AS2	-0.403
SLC13A5	-0.393
ACBD7	-0.392
TNS3	-0.388
APCDD1	-0.38
GPAM	-0.365
CABLES1	-0.362
NWD1	-0.359

DrugBank
CTD

There is no DrugBank record for this gene !

ID	Drug Name	Action	PubMed
C548651	2-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester	2-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester results in decreased expression of PRR15 mRNA	19933214
C006551	2-amino-2-methyl-1-propanol	2-amino-2-methyl-1-propanol results in decreased expression of PRR15 mRNA	25088246
C459179	4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide	"[NOG protein co-treated with belinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PRR15 mRNA"	27188386
C459179	4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide	"[NOG protein co-treated with entinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PRR15 mRNA"	27188386
C459179	4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide	"[NOG protein co-treated with panobinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PRR15 mRNA"	27188386
C459179	4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide	"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PRR15 mRNA"	27188386
C516138	(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine	"[NOG protein co-treated with belinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PRR15 mRNA"	27188386
C516138	(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine	"[NOG protein co-treated with entinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PRR15 mRNA"	27188386
C516138	(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine	"[NOG protein co-treated with panobinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PRR15 mRNA"	27188386
C516138	(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine	"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PRR15 mRNA"	27188386
C487081	belinostat	"[NOG protein co-treated with belinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PRR15 mRNA"	27188386
D001564	Benzo(a)pyrene	Benzo(a)pyrene results in increased expression of PRR15 mRNA	19770486\|2171566
D015123	7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide	"7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of PRR15 mRNA"	19150397
C038328	BEP protocol	BEP protocol results in increased expression of PRR15 mRNA	18987330
C095105	bexarotene	[bexarotene co-treated with Tamoxifen] results in increased expression of PRR15 mRNA	17630414
C006780	bisphenol A	bisphenol A results in decreased expression of PRR15 mRNA	27685785
C006780	bisphenol A	[bisphenol A co-treated with Testosterone] results in increased expression of PRR15 mRNA	26496021
C006780	bisphenol A	bisphenol A results in increased expression of PRR15 mRNA	25181051
C006780	bisphenol A	bisphenol A results in increased methylation of PRR15 gene	28505145
D002737	Chloroprene	Chloroprene results in decreased expression of PRR15 mRNA	23125180
D002794	Choline	[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of PRR15 gene	20938992
C074702	chromium hexavalent ion	chromium hexavalent ion affects the expression of PRR15 mRNA	28472532
D003300	Copper	[Copper co-treated with Dietary Sucrose] results in decreased expression of PRR15 mRNA	26033743
D003375	Coumestrol	Coumestrol results in decreased expression of PRR15 mRNA	19167446
D016572	Cyclosporine	Cyclosporine results in decreased expression of PRR15 mRNA	25562108
D016572	Cyclosporine	Cyclosporine results in decreased expression of PRR15 mRNA	19770486
D016572	Cyclosporine	Cyclosporine results in increased expression of PRR15 protein	25047351
D003999	Dichloroacetic Acid	Dichloroacetic Acid results in increased expression of PRR15 mRNA	28962523
D002945	Cisplatin	[Cisplatin co-treated with jinfukang] results in increased expression of PRR15 mRNA	27392435
D019422	Dietary Sucrose	[Copper co-treated with Dietary Sucrose] results in decreased expression of PRR15 mRNA	26033743
D019422	Dietary Sucrose	Dietary Sucrose results in decreased expression of PRR15 mRNA	26033743
C118739	entinostat	entinostat results in increased expression of PRR15 mRNA	26272509
C118739	entinostat	"[NOG protein co-treated with entinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PRR15 mRNA"	27188386
D005492	Folic Acid	[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of PRR15 gene	20938992
C004312	glycidol	glycidol results in increased expression of PRR15 mRNA	24915197
C412815	GW 4064	GW 4064 results in decreased expression of PRR15 mRNA	26655953
D015759	Ionomycin	[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of PRR15 mRNA	25613284
C544151	jinfukang	[Cisplatin co-treated with jinfukang] results in increased expression of PRR15 mRNA	27392435
C544151	jinfukang	jinfukang results in increased expression of PRR15 mRNA	27392435
C561695	(+)-JQ1 compound	(+)-JQ1 compound results in decreased expression of PRR15 mRNA	27432991
D008715	Methionine	[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of PRR15 gene	20938992
D037742	Nanotubes, Carbon	"Nanotubes, Carbon analog results in decreased expression of PRR15 mRNA"	25554681
D010100	Oxygen	Oxygen deficiency results in increased expression of PRR15 mRNA	20880076
C496932	panobinostat	"[NOG protein co-treated with panobinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PRR15 mRNA"	27188386
C496932	panobinostat	panobinostat results in increased expression of PRR15 mRNA	26272509
C006253	pirinixic acid	[pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of PRR15 mRNA	19710929
D011374	Progesterone	Progesterone results in increased expression of PRR15 mRNA	23012394\|2301818
D011374	Progesterone	Progesterone results in increased expression of PRR15 mRNA	20864642
D011374	Progesterone	Progesterone results in decreased expression of PRR15 mRNA	19690047
D011441	Propylthiouracil	Propylthiouracil results in increased expression of PRR15 mRNA	24780913
D011794	Quercetin	Quercetin results in decreased expression of PRR15 mRNA	21632981
C009250	sevoflurane	sevoflurane results in decreased expression of PRR15 mRNA	26206149
D012822	Silicon Dioxide	Silicon Dioxide analog results in decreased expression of PRR15 mRNA	23806026\|2589566
C009277	sodium arsenate	sodium arsenate results in decreased expression of PRR15 mRNA	21795629
C017947	sodium arsenite	sodium arsenite results in decreased expression of PRR15 mRNA	28595984
D013629	Tamoxifen	[bexarotene co-treated with Tamoxifen] results in increased expression of PRR15 mRNA	17630414
D013739	Testosterone	[bisphenol A co-treated with Testosterone] results in increased expression of PRR15 mRNA	26496021
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin results in increased expression of PRR15 mRNA	20106945\|2163298
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin affects the expression of PRR15 mRNA	26377647
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin results in decreased expression of PRR15 mRNA	19933214
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin results in increased expression of PRR15 mRNA	19770486\|2629044
D013755	Tetradecanoylphorbol Acetate	[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of PRR15 mRNA	25613284
C009495	titanium dioxide	titanium dioxide results in increased expression of PRR15 mRNA	23557971
D014028	Tobacco Smoke Pollution	Tobacco Smoke Pollution results in decreased methylation of PRR15 gene	26756918
D014520	Urethane	Urethane results in decreased expression of PRR15 mRNA	28818685
D014635	Valproic Acid	"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PRR15 mRNA"	27188386
D014635	Valproic Acid	Valproic Acid results in increased expression of PRR15 mRNA	23179753\|2438349

Gene: PRR15

DNA Methylation

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Top 10 negatively co-expressed genes

Drugs/Compounds

There is no DrugBank record for this gene !

GO/Pathway

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)