Gene: RSBN1L

222194
-
round spermatid basic protein 1 like
protein-coding
7q11.23
Ensembl:ENSG00000187257 Vega:OTTHUMG00000155517 UniprotKB:Q6PCB5
NC_000007.14
SNP Mapped
1   ANCO-SNPs
AD
0   
NA (AD)  NA (ND)   (Frontal_Cortex)
7.330e-1 (AD)  5.631e-2 (ND)

ANCO-SNPs

SNP ID Position Alleles Trait Variation Type
rs35216166chr7:77698016 (GRCh38.p7)G>Aalcohol dependenceSNV(Single Nucleotide Variation)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
ATF20.93
PPP1R12A0.919
MAP4K30.916
RBM260.914
RHOT10.912
CCNT20.912
CD470.912
THUMPD10.911
GOPC0.911
PUM10.91

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
OR4F5-0.613
OR4F29-0.566
CSAG1-0.248
TFPI2-0.233
FZD10-0.231
NANOGNB-0.223
S100A14-0.223
AQP5-0.22
KLRB1-0.216
MDFI-0.211

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C0164032,4-dinitrotoluene"2,4-dinitrotoluene affects the expression of RSBN1L mRNA"21346803
C5724913-(2-hydroxy-4-(2-methylnonan-2-yl)phenyl)cyclohexan-1-ol3-(2-hydroxy-4-(2-methylnonan-2-yl)phenyl)cyclohexan-1-ol results in decreased expression of RSBN1L protein26194647
D000082AcetaminophenAcetaminophen results in decreased expression of RSBN1L mRNA21420995
D000082AcetaminophenAcetaminophen affects the expression of RSBN1L mRNA17562736
D020106AcrylamideAcrylamide results in decreased expression of RSBN1L mRNA28959563
D000395Air Pollutants, Occupational"Air Pollutants, Occupational results in decreased expression of RSBN1L mRNA"23195993
D001564Benzo(a)pyreneBenzo(a)pyrene results in decreased expression of RSBN1L mRNA20064835
D0151237,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide"7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide affects the expression of RSBN1L mRNA"20382639
D0151237,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide"7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of RSBN1L mRNA"19150397
C044887beta-methylcholinebeta-methylcholine affects the expression of RSBN1L mRNA21179406
C006780bisphenol Abisphenol A results in decreased expression of RSBN1L mRNA25181051
D003042CocaineCocaine results in increased expression of RSBN1L mRNA17898221
D016572CyclosporineCyclosporine results in increased expression of RSBN1L mRNA19159671
D004791Enzyme Inhibitors[Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation of RSBN1L protein23301498
D005557FormaldehydeFormaldehyde results in decreased expression of RSBN1L mRNA20655997
C492448ICG 001ICG 001 results in decreased expression of RSBN1L mRNA26191083
C045463leflunomideleflunomide results in increased expression of RSBN1L mRNA28988120
D018817N-Methyl-3,4-methylenedioxyamphetamine"N-Methyl-3,4-methylenedioxyamphetamine results in decreased expression of RSBN1L mRNA"26251327
C028577monobutyl phthalatemonobutyl phthalate results in increased expression of RSBN1L mRNA29162477
D009532NickelNickel results in decreased expression of RSBN1L mRNA23195993
C568608PCI 5002[PCI 5002 co-treated with Zinc] results in increased expression of RSBN1L mRNA18593933
D010936Plant ExtractsPlant Extracts results in increased expression of RSBN1L mRNA23557933
C059514resveratrolresveratrol results in decreased expression of RSBN1L protein25505154
D014520UrethaneUrethane results in decreased expression of RSBN1L mRNA28818685
D014635Valproic AcidValproic Acid results in decreased expression of RSBN1L mRNA28001369
D015032Zinc[PCI 5002 co-treated with Zinc] results in increased expression of RSBN1L mRNA18593933

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO ID GO Term Qualifier Evidence PubMed
GO ID GO Term Qualifier Evidence PubMed
GO:0005634nucleus-IEA-  
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal