Gene: CCDC129

223075
-
coiled-coil domain containing 129
protein-coding
7p14.3
Ensembl:ENSG00000180347 Vega:OTTHUMG00000128611 UniprotKB:Q6ZRS4
NG_051956.1
SNP Mapped
1   ANCO-SNPs
ND
0   
NA (AD)  NA (ND)   (Frontal_Cortex)
6.725e-1 (AD)  2.791e-1 (ND)

ANCO-SNPs

SNP ID Position Alleles Trait Variation Type
rs6963296chr7:31576040 (GRCh38.p7)T>Cnicotine dependenceSNV(Single Nucleotide Variation)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
PPP1R170.681
GPRIN20.648
COL25A10.591
RAB3B0.59
TENM10.586
PCSK10.583
HTR70.582
SPHKAP0.576
SAMD50.555
CHRM20.552

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
IMPA2-0.451
PLIN4-0.424
RFX2-0.415
EMX2-0.402
HIGD1B-0.381
EYA2-0.38
RHOJ-0.378
NBPF10-0.376
STON2-0.374
PHF21B-0.372

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C0297902,2',3',4,4',5-hexachlorobiphenyl"[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in decreased expression of CCDC129 mRNA"25510870
C0817662,4,4'-trichlorobiphenyl"[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in decreased expression of CCDC129 mRNA"25510870
C0140242,4,5,2',4',5'-hexachlorobiphenyl"[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in decreased expression of CCDC129 mRNA"25510870
C0098282,4,5,2',5'-pentachlorobiphenyl"[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in decreased expression of CCDC129 mRNA"25510870
C0094072,5,2',5'-tetrachlorobiphenyl"[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in decreased expression of CCDC129 mRNA"25510870
D016604Aflatoxin B1Aflatoxin B1 results in decreased methylation of CCDC129 gene27153756
D001151ArsenicArsenic affects the methylation of CCDC129 gene25304211
D004958EstradiolEstradiol results in increased expression of CCDC129 mRNA19484750
C006780bisphenol A[bisphenol A co-treated with Testosterone] results in decreased expression of CCDC129 mRNA26496021
D037742Nanotubes, Carbon"Nanotubes, Carbon analog results in decreased expression of CCDC129 mRNA"25554681
D037742Nanotubes, Carbon"Nanotubes, Carbon results in decreased expression of CCDC129 mRNA"25554681
D009532NickelNickel results in decreased expression of CCDC129 mRNA25583101
C410127PCB 180"[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in decreased expression of CCDC129 mRNA"25510870
D053260SootSoot results in decreased expression of CCDC129 mRNA26551751
D013739Testosterone[bisphenol A co-treated with Testosterone] results in decreased expression of CCDC129 mRNA26496021
C009495titanium dioxidetitanium dioxide affects the expression of CCDC129 mRNA23557971
C009495titanium dioxidetitanium dioxide results in decreased expression of CCDC129 mRNA28181387

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0005102signaling receptor binding-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO ID GO Term Qualifier Evidence PubMed
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal