Gene info: ID 2274

Gene: FHL2

GENE ID: 2274

Synonyms: AAG11|DRAL|FHL-2|SLIM-3|SLIM3

Description: four and a half LIM domains 2

Gene type: protein-coding

Location: 2q12.2

dbXrefs: Ensembl:ENSG00000115641 MIM:602633 Vega:OTTHUMG00000153120 UniprotKB:Q14192

RefSeq: NG_008844.2

Retrived from: PubMed

SNPs: 0 ANCO-SNPs

Phenotype: ND

# Publications: 1

Sherlock p-value : NA (AD) NA (ND) (Frontal_Cortex)

Pascal p-value : 5.970e-1 (AD) 9.238e-1 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol	Pearson Correlation Coefficient
SPATS2	0.919
SERPINF1	0.91
PREP	0.905
OSBPL10	0.903
SEPT6	0.903
LDB2	0.901
NUAK1	0.901
KCNK1	0.901
PAK1	0.898
STAMBPL1	0.894

Top 10 negatively co-expressed genes

Gene Symbol	Pearson Correlation Coefficient
PARD3B	-0.584
ASB4	-0.576
MYOM1	-0.572
MBNL3	-0.559
LRAT	-0.559
CYP11A1	-0.544
YES1	-0.543
STON2	-0.542
HEY2	-0.534
HOGA1	-0.52

There is no DrugBank record for this gene !

ID	Drug Name	Action	PubMed
C511295	2,2',4,4'-tetrabromodiphenyl ether	"2,2',4,4'-tetrabromodiphenyl ether analog results in increased expression of FHL2 mRNA"	19095052
C111118	2',3,3',4',5-pentachloro-4-hydroxybiphenyl	"2',3,3',4',5-pentachloro-4-hydroxybiphenyl results in decreased expression of FHL2 mRNA"	19114083
C023035	3,4,5,3',4'-pentachlorobiphenyl	"3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of FHL2 mRNA"	19692669
C009505	4,4'-diaminodiphenylmethane	"4,4'-diaminodiphenylmethane results in increased expression of FHL2 mRNA"	18648102
C009505	4,4'-diaminodiphenylmethane	"4,4'-diaminodiphenylmethane results in increased expression of FHL2 mRNA"	25380136
D000082	Acetaminophen	Acetaminophen results in increased expression of FHL2 mRNA	29067470
D000082	Acetaminophen	Acetaminophen affects the expression of FHL2 mRNA	17562736
D020106	Acrylamide	Acrylamide results in increased expression of FHL2 mRNA	28959563
D016604	Aflatoxin B1	Aflatoxin B1 affects the expression of FHL2 protein	20106945
D016604	Aflatoxin B1	Aflatoxin B1 results in increased expression of FHL2 mRNA	22100608\|2715375
D016604	Aflatoxin B1	Aflatoxin B1 results in decreased expression of FHL2 mRNA	19770486
D000447	Aldehydes	Aldehydes results in increased expression of FHL2 mRNA	25014914
D013196	Dihydrotestosterone	AHR protein inhibits the reaction [[FHL2 protein co-treated with Tetrachlorodibenzodioxin] inhibits the reaction [Dihydrotestosterone results in increased activity of AR protein]]	19815066
D013196	Dihydrotestosterone	FHL2 protein affects the reaction [[Dihydrotestosterone co-treated with Tetrachlorodibenzodioxin] results in increased activity of AR protein]	19815066
D013196	Dihydrotestosterone	[FHL2 protein co-treated with Tetrachlorodibenzodioxin] inhibits the reaction [Dihydrotestosterone results in increased activity of AR protein]	19815066
D013196	Dihydrotestosterone	FHL2 protein inhibits the reaction [AHR protein promotes the reaction [Dihydrotestosterone results in increased activity of AR protein]]	19815066
D013196	Dihydrotestosterone	FHL2 protein promotes the reaction [Dihydrotestosterone results in increased activity of AR protein]	19815066
D000643	Ammonium Chloride	Ammonium Chloride affects the expression of FHL2 mRNA	16483693
D018501	Antirheumatic Agents	Antirheumatic Agents results in increased expression of FHL2 mRNA	24449571
C006632	arsenic trioxide	arsenic trioxide results in increased expression of FHL2 mRNA	26705709
D017638	Asbestos, Crocidolite	"Asbestos, Crocidolite affects the expression of FHL2 mRNA"	17331233
C006703	benzo(b)fluoranthene	benzo(b)fluoranthene results in decreased expression of FHL2 mRNA	26377693
D019324	beta-Naphthoflavone	[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of FHL2 mRNA	18164116
D001564	Benzo(a)pyrene	Benzo(a)pyrene results in increased expression of FHL2 mRNA	22316170
D001564	Benzo(a)pyrene	Benzo(a)pyrene results in decreased expression of FHL2 mRNA	22228805
C072553	benzyloxycarbonylleucyl-leucyl-leucine aldehyde	benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of FHL2 mRNA	25566086
D004958	Estradiol	EGF protein promotes the reaction [Estradiol results in increased expression of FHL2 mRNA]	24758408
D004958	Estradiol	Estradiol affects the expression of FHL2 mRNA	14699072
D004958	Estradiol	[Estradiol co-treated with Progesterone] results in decreased expression of FHL2 mRNA	20660070
D004958	Estradiol	[Estradiol co-treated with Tetrachlorodibenzodioxin] results in decreased expression of FHL2 mRNA	19619570
D004958	Estradiol	Estradiol promotes the reaction [FHL2 protein binds to ESR1 protein]	15666801
D004958	Estradiol	Estradiol results in increased expression of FHL2 mRNA	19619570\|2010694
D004958	Estradiol	Estradiol results in increased expression of FHL2 mRNA	19484750
D004958	Estradiol	[bisphenol A co-treated with Estradiol] results in increased expression of FHL2 mRNA	26496021
C044887	beta-methylcholine	beta-methylcholine affects the expression of FHL2 mRNA	21179406
C006780	bisphenol A	bisphenol A affects the expression of FHL2 mRNA	20170705
C006780	bisphenol A	bisphenol A results in decreased expression of FHL2 mRNA	29275510
C006780	bisphenol A	[bisphenol A co-treated with Estradiol] results in increased expression of FHL2 mRNA	26496021
C006780	bisphenol A	bisphenol A results in decreased expression of FHL2 mRNA	25181051
C006780	bisphenol A	[Fructose co-treated with bisphenol A] results in decreased expression of FHL2 protein	26930160
D015124	8-Bromo Cyclic Adenosine Monophosphate	8-Bromo Cyclic Adenosine Monophosphate results in increased expression of FHL2 mRNA	22079614
D020122	tert-Butylhydroperoxide	tert-Butylhydroperoxide results in increased expression of FHL2 mRNA	15336504
C018475	butyraldehyde	butyraldehyde results in increased expression of FHL2 mRNA	26079696
D002104	Cadmium	Cadmium results in increased expression of FHL2 mRNA	24284285
D002220	Carbamazepine	Carbamazepine affects the expression of FHL2 mRNA	25979313
D002251	Carbon Tetrachloride	Carbon Tetrachloride results in increased expression of FHL2 mRNA	17484886
D002251	Carbon Tetrachloride	Carbon Tetrachloride results in increased expression of FHL2 mRNA	16239168
D002330	Carmustine	FHL2 mRNA affects the susceptibility to Carmustine	16365179
C100187	chloropicrin	chloropicrin results in increased expression of FHL2 mRNA	26352163
D002794	Choline	[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of FHL2 mRNA	20938992
C018021	cobaltous chloride	cobaltous chloride results in increased expression of FHL2 mRNA	19376846
D003300	Copper	[NSC 689534 binds to Copper] which results in increased expression of FHL2 mRNA	20971185
D019327	Copper Sulfate	Copper Sulfate results in increased expression of FHL2 mRNA	19549813
D003375	Coumestrol	[Coumestrol co-treated with resveratrol] results in increased expression of FHL2 mRNA	19167446
D003375	Coumestrol	Coumestrol results in increased expression of FHL2 mRNA	19167446
D016572	Cyclosporine	Cyclosporine results in increased expression of FHL2 mRNA	20106945\|2556210
C089595	cylindrospermopsin	cylindrospermopsin results in increased expression of FHL2 mRNA	24921660
C004742	daidzein	[daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of FHL2 mRNA	27424125
C013908	daidzin	[daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of FHL2 mRNA	27424125
C515055	darinaparsin	darinaparsin results in increased expression of FHL2 mRNA	22535156
C014347	decitabine	[decitabine co-treated with vorinostat] affects the expression of FHL2 mRNA	17330099
D003907	Dexamethasone	Dexamethasone results in decreased expression of FHL2 mRNA	25047013
D003993	Dibutyl Phthalate	Dibutyl Phthalate results in increased expression of FHL2 mRNA	21266533
D003993	Dibutyl Phthalate	Dibutyl Phthalate results in increased expression of FHL2 mRNA	21266533
D002945	Cisplatin	Cisplatin results in increased expression of FHL2 mRNA	21151649
D002945	Cisplatin	Cisplatin results in decreased expression of FHL2 mRNA	22023808
D004041	Dietary Fats	Dietary Fats results in decreased expression of FHL2 mRNA	25016146
D004041	Dietary Fats	Dietary Fats results in increased expression of FHL2 mRNA	18042831
D004052	Diethylnitrosamine	[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of FHL2 mRNA	18164116
D004054	Diethylstilbestrol	Diethylstilbestrol results in increased expression of FHL2 mRNA	19371625\|2686566
D002117	Calcitriol	Calcitriol results in increased expression of FHL2 mRNA	21592394
D002117	Calcitriol	[Testosterone co-treated with Calcitriol] results in increased expression of FHL2 mRNA	21592394
D015127	9,10-Dimethyl-1,2-benzanthracene	"9,10-Dimethyl-1,2-benzanthracene results in increased expression of FHL2 mRNA"	19480007
D004128	Dimethylnitrosamine	Dimethylnitrosamine results in increased expression of FHL2 mRNA	25380136
D004237	Diuron	Diuron results in increased expression of FHL2 mRNA	21551480
D004317	Doxorubicin	Doxorubicin results in decreased expression of FHL2 mRNA	28940058
D004317	Doxorubicin	FHL2 protein affects the reaction [Doxorubicin results in increased expression of CDKN1A protein]	17682292
D004317	Doxorubicin	TP53 protein affects the reaction [FHL2 protein affects the reaction [Doxorubicin results in increased expression of CDKN1A protein]]	17682292
D004317	Doxorubicin	Doxorubicin results in decreased expression of FHL2 mRNA	25896364
D004317	Doxorubicin	Doxorubicin results in decreased expression of FHL2 protein	21251210
D004970	Estrone	Estrone results in increased expression of FHL2 mRNA	26865669
D004997	Ethinyl Estradiol	Ethinyl Estradiol affects the expression of FHL2 mRNA	20170705
D004997	Ethinyl Estradiol	Ethinyl Estradiol affects the expression of FHL2 mRNA	17555576
D004997	Ethinyl Estradiol	[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of FHL2 mRNA	17942748
D008656	Mestranol	Mestranol results in increased expression of FHL2 mRNA	26865669
D005020	Ethyl Methanesulfonate	Ethyl Methanesulfonate results in increased expression of FHL2 mRNA	23649840
D005472	Fluorouracil	FHL2 protein affects the susceptibility to Fluorouracil	16217747
D005473	Fluoxetine	Fluoxetine results in decreased expression of FHL2 mRNA	21852994
D005485	Flutamide	Flutamide results in decreased expression of FHL2 mRNA	24793618
D005492	Folic Acid	[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of FHL2 mRNA	20938992
D005557	Formaldehyde	Formaldehyde results in increased expression of FHL2 mRNA	23649840
D005632	Fructose	[Fructose co-treated with bisphenol A] results in decreased expression of FHL2 protein	26930160
C070081	fulvestrant	fulvestrant results in decreased expression of FHL2 mRNA	26865669
C039281	furan	furan results in increased expression of FHL2 mRNA	27387713
D019833	Genistein	[daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of FHL2 mRNA	27424125
D019833	Genistein	ESR2 promotes the reaction [Genistein results in decreased expression of FHL2 protein]	20884965
D019833	Genistein	Genistein results in decreased expression of FHL2 mRNA	20884965
D019833	Genistein	Genistein results in decreased expression of FHL2 protein	20884965
D019833	Genistein	Genistein results in increased expression of FHL2 mRNA	23019147\|2686566
C040641	genistin	[daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of FHL2 mRNA	27424125
C086566	glycitein	[daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of FHL2 mRNA	27424125
C433283	glycitin	[daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of FHL2 mRNA	27424125
D006589	Hexestrol	Hexestrol results in increased expression of FHL2 mRNA	26865669
C029424	hydrazine	hydrazine results in decreased expression of FHL2 mRNA	15282401
D006861	Hydrogen Peroxide	Hydrogen Peroxide affects the expression of FHL2 mRNA	20044591
D015759	Ionomycin	[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of FHL2 mRNA	25613284
C561695	(+)-JQ1 compound	(+)-JQ1 compound results in decreased expression of FHL2 mRNA	24796395
D007657	Ketone Bodies	Ketone Bodies results in increased expression of FHL2 mRNA	16807920
C045463	leflunomide	leflunomide results in increased expression of FHL2 mRNA	28988120
C052901	lemongrass oil	lemongrass oil affects the expression of FHL2 mRNA	25976427
D008715	Methionine	[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of FHL2 mRNA	20938992
C004925	methylmercuric chloride	methylmercuric chloride results in increased expression of FHL2 mRNA	28001369
D008741	Methyl Methanesulfonate	Methyl Methanesulfonate results in increased expression of FHL2 mRNA	23649840
C008493	methylselenic acid	methylselenic acid results in increased expression of FHL2 mRNA	18548127
C406082	monomethylarsonous acid	monomethylarsonous acid results in increased expression of FHL2 protein	24625837
D009020	Morphine	Morphine deficiency inhibits the reaction [Morphine deficiency inhibits the reaction [Morphine results in decreased expression of FHL2 protein]]	23056601
D009020	Morphine	Morphine deficiency inhibits the reaction [Morphine results in decreased expression of FHL2 protein]	23056601
D009020	Morphine	Morphine results in decreased expression of FHL2 protein	23056601
D015058	1-Naphthylisothiocyanate	1-Naphthylisothiocyanate results in increased expression of FHL2 mRNA	25380136
C558013	NSC 689534	[NSC 689534 binds to Copper] which results in increased expression of FHL2 mRNA	20971185
C030110	oxaliplatin	[oxaliplatin co-treated with Topotecan] results in increased expression of FHL2 mRNA	25729387
C030110	oxaliplatin	oxaliplatin results in increased expression of FHL2 mRNA	25729387
D000073878	Palm Oil	Palm Oil results in increased expression of FHL2 mRNA	18042831
C086401	pentabromodiphenyl ether	pentabromodiphenyl ether analog results in increased expression of FHL2 mRNA	19095052
C046012	pentanal	pentanal results in increased expression of FHL2 mRNA	26079696
C023036	perfluorooctanoic acid	perfluorooctanoic acid results in increased expression of FHL2 mRNA	25868421
D010634	Phenobarbital	Phenobarbital affects the expression of FHL2 mRNA	19159669
D010656	Phenylephrine	FHL2 gene mutant form results in decreased susceptibility to Phenylephrine	25358972
C006253	pirinixic acid	[pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of FHL2 mRNA	19710929
C006253	pirinixic acid	pirinixic acid results in decreased expression of FHL2 mRNA	17426115
D011192	Potassium Dichromate	Potassium Dichromate results in decreased expression of FHL2 protein	23718831
D011374	Progesterone	[Estradiol co-treated with Progesterone] results in decreased expression of FHL2 mRNA	20660070
C005556	propionaldehyde	propionaldehyde results in increased expression of FHL2 mRNA	26079696
D020849	Raloxifene Hydrochloride	Raloxifene Hydrochloride affects the expression of FHL2 mRNA	14699072
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of FHL2 mRNA	19059307
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of FHL2 mRNA	19059307
D020849	Raloxifene Hydrochloride	Raloxifene Hydrochloride results in decreased expression of FHL2 mRNA	26865669
C059514	resveratrol	[Coumestrol co-treated with resveratrol] results in increased expression of FHL2 mRNA	19167446
C064116	S-(1,1,2,2-tetrafluoroethyl)cysteine	"S-(1,1,2,2-tetrafluoroethyl)cysteine results in increased expression of FHL2 mRNA"	16678137
C009250	sevoflurane	sevoflurane results in decreased expression of FHL2 mRNA	26206149
D012834	Silver	Silver results in increased expression of FHL2 mRNA	28959546
C017947	sodium arsenite	sodium arsenite affects the methylation of FHL2 gene	28589171
C017947	sodium arsenite	sodium arsenite results in decreased expression of and affects the splicing of FHL2 mRNA	25879800
D018038	Sodium Selenite	Sodium Selenite results in increased expression of FHL2 mRNA	24383545
D013467	Sulindac	Sulindac results in increased expression of FHL2 mRNA	11906190
D013629	Tamoxifen	Tamoxifen affects the expression of FHL2 mRNA	14699072
D013629	Tamoxifen	[Tamoxifen co-treated with ESR1 protein] results in increased expression of FHL2 mRNA	19059307
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in decreased expression of FHL2 mRNA	19059307
D013629	Tamoxifen	Tamoxifen affects the expression of FHL2 mRNA	17555576
C047246	temozolomide	FHL2 mRNA affects the susceptibility to temozolomide	16365179
D013739	Testosterone	[Testosterone co-treated with Calcitriol] results in increased expression of FHL2 mRNA	21592394
D013739	Testosterone	Testosterone results in increased expression of FHL2 mRNA	21592394
C045037	testosterone-3-carboxymethyloxime-bovine serum albumin conjugate	testosterone-3-carboxymethyloxime-bovine serum albumin conjugate results in increased expression of FHL2 mRNA	20189893
C020806	tetrabromobisphenol A	tetrabromobisphenol A results in increased expression of FHL2 mRNA	25172293
D013749	Tetrachlorodibenzodioxin	AHR protein inhibits the reaction [[FHL2 protein co-treated with Tetrachlorodibenzodioxin] inhibits the reaction [Dihydrotestosterone results in increased activity of AR protein]]	19815066
D013749	Tetrachlorodibenzodioxin	[Estradiol co-treated with Tetrachlorodibenzodioxin] results in decreased expression of FHL2 mRNA	19619570
D013749	Tetrachlorodibenzodioxin	FHL2 protein affects the reaction [[Dihydrotestosterone co-treated with Tetrachlorodibenzodioxin] results in increased activity of AR protein]	19815066
D013749	Tetrachlorodibenzodioxin	[FHL2 protein co-treated with Tetrachlorodibenzodioxin] inhibits the reaction [Dihydrotestosterone results in increased activity of AR protein]	19815066
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin affects the expression of FHL2 mRNA	22298810
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin results in increased expression of FHL2 mRNA	19619570
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin affects the expression of FHL2 mRNA	21570461
D013749	Tetrachlorodibenzodioxin	[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of FHL2 mRNA	17942748
D013755	Tetradecanoylphorbol Acetate	[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of FHL2 mRNA	25613284
C009495	titanium dioxide	titanium dioxide results in decreased expression of FHL2 mRNA	23557971
D019772	Topotecan	[oxaliplatin co-treated with Topotecan] results in increased expression of FHL2 mRNA	25729387
D019772	Topotecan	Topotecan results in increased expression of FHL2 mRNA	25729387
D014212	Tretinoin	Tretinoin results in increased expression of FHL2 mRNA	23724009
C011559	tributyltin	tributyltin results in increased expression of FHL2 mRNA	27614199
C015559	trimellitic anhydride	trimellitic anhydride results in increased expression of FHL2 mRNA	19042947
C016805	tris(1,3-dichloro-2-propyl)phosphate	"tris(1,3-dichloro-2-propyl)phosphate results in increased expression of FHL2 mRNA"	26179874
C013320	tris(2-butoxyethyl) phosphate	tris(2-butoxyethyl) phosphate affects the expression of FHL2 mRNA	29024780
D014635	Valproic Acid	Valproic Acid affects the expression of FHL2 mRNA	25979313
D014635	Valproic Acid	Valproic Acid results in increased expression of FHL2 mRNA	23179753\|2519280
D001335	Vehicle Emissions	Vehicle Emissions results in decreased methylation of FHL2 gene	25560391
D024483	Vitamin K 3	Vitamin K 3 affects the expression of FHL2 mRNA	20044591
C111237	vorinostat	[decitabine co-treated with vorinostat] affects the expression of FHL2 mRNA	17330099
C088658	zoledronic acid	zoledronic acid results in decreased expression of FHL2 mRNA	24714768

GO/Pathway

GO ID	GO Term	Qualifier	Evidence	PubMed
GO:0003712	transcription coregulator activity	-	IBA	21873635
GO:0003713	transcription coactivator activity	-	NAS	15572661
GO:0005515	protein binding	-	IPI	10654935 10906324 11001931 11135358 12067710 14550570 15692560 16624878 16888242 17360532 18255255 19608030 21516116 21988832 22829078 25416956 26871637 28717008
GO:0008134	transcription factor binding	-	IPI	15692560
GO:0042802	identical protein binding	-	IPI	10906324 18255255
GO:0046872	metal ion binding	-	IEA	-
GO:0050681	androgen receptor binding	-	NAS	15572661

GO ID	GO Term	Qualifier	Evidence	PubMed
GO:0000122	negative regulation of transcription by RNA polymerase II	-	IDA	15692560
GO:0001649	osteoblast differentiation	-	IEA	-
GO:0006351	transcription, DNA-templated	-	IEA	-
GO:0009725	response to hormone	-	IMP	17975004
GO:0019216	regulation of lipid metabolic process	-	TAS	-
GO:0030521	androgen receptor signaling pathway	-	NAS	15572661
GO:0043066	negative regulation of apoptotic process	-	IDA	15692560
GO:0045893	positive regulation of transcription, DNA-templated	-	NAS	15572661
GO:0055014	atrial cardiac muscle cell development	-	IEA	-
GO:0055015	ventricular cardiac muscle cell development	-	IEA	-
GO:0060347	heart trabecula formation	-	IEA	-
GO:0070885	negative regulation of calcineurin-NFAT signaling cascade	-	IMP	22851699

GO ID	GO Term	Qualifier	Evidence	PubMed
GO:0005634	nucleus	-	IBA	21873635
GO:0005634	nucleus	-	TAS	9150430
GO:0005654	nucleoplasm	-	TAS	-
GO:0005925	focal adhesion	-	HDA	21423176
GO:0030018	Z disc	-	IBA	21873635
GO:0030018	Z disc	-	IEA	-
GO:0031430	M band	-	IEA	-

KEGG ID	KEGG Term
hsa04380	Osteoclast differentiation

Reactome ID	Reactome Term	Evidence
R-HSA-1430728	Metabolism	TAS
R-HSA-1989781	PPARA activates gene expression	TAS
R-HSA-400206	Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)	TAS
R-HSA-556833	Metabolism of lipids	TAS

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID	Title (Year)	Author	Journal
21801107	Gene expression signatures of radiation exposure in peripheral white blood cells of smokers and non-smokers. (2011 Aug)	Paul S	Int J Radiat Biol