Gene: PCNX1

22990
PCNX|PCNXL1|pecanex
pecanex homolog 1
protein-coding
14q24.2
Ensembl:ENSG00000100731 MIM:617655 Vega:OTTHUMG00000171242 UniprotKB:Q96RV3
NG_051070.1
SNP Mapped
1   ANCO-SNPs
AD
0   
NA (AD)  NA (ND)   (Frontal_Cortex)
1.389e-1 (AD)  1.926e-1 (ND)

ANCO-SNPs

SNP ID Position Alleles Trait Variation Type
rs2810114chr14:70928887 (GRCh38.p7)C>Aalcohol dependenceSNV(Single Nucleotide Variation)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
D000082AcetaminophenAcetaminophen results in increased expression of PCNX1 mRNA22230336
D001151ArsenicArsenic affects the methylation of PCNX1 gene25304211
D001280AtrazineAtrazine results in increased expression of PCNX1 mRNA22378314
C006780bisphenol Abisphenol A results in decreased expression of PCNX1 mRNA25181051
D002392Catechin[Catechin co-treated with Grape Seed Proanthocyanidins] results in increased expression of PCNX1 mRNA24763279
D004997Ethinyl EstradiolEthinyl Estradiol results in increased expression of PCNX1 mRNA29097150
D005557FormaldehydeFormaldehyde results in decreased expression of PCNX1 mRNA20655997
D005947Glucose[INS protein co-treated with Glucose] results in decreased expression of PCNX1 mRNA22634610
C511402Grape Seed Proanthocyanidins[Catechin co-treated with Grape Seed Proanthocyanidins] results in increased expression of PCNX1 mRNA24763279
D017313FenretinideFenretinide results in decreased expression of PCNX1 mRNA28973697
C492448ICG 001ICG 001 results in decreased expression of PCNX1 mRNA26191083
C561695(+)-JQ1 compound(+)-JQ1 compound results in increased expression of PCNX1 mRNA24796395
C410337K 7174K 7174 results in increased expression of PCNX1 mRNA24086573
D008741Methyl MethanesulfonateMethyl Methanesulfonate results in increased expression of PCNX1 mRNA23649840
D009532NickelNickel results in increased expression of PCNX1 mRNA24768652|2558310
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased expression of PCNX1 mRNA18796159
C012589trichostatin Atrichostatin A results in increased expression of PCNX1 mRNA24935251
D014635Valproic AcidValproic Acid affects the expression of PCNX1 mRNA23179753
D014635Valproic AcidValproic Acid results in decreased expression of PCNX1 mRNA24383497|2493525
D014635Valproic AcidValproic Acid results in increased expression of PCNX1 mRNA19101580
D014750VincristineVincristine results in increased expression of PCNX1 mRNA23649840

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO ID GO Term Qualifier Evidence PubMed
GO ID GO Term Qualifier Evidence PubMed
GO:0016021integral component of membrane-IEA-  
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal