Gene: FMR1

2332
FMRP|FRAXA|POF|POF1
fragile X mental retardation 1
protein-coding
Xq27.3
Ensembl:ENSG00000102081 MIM:309550 Vega:OTTHUMG00000022606 UniprotKB:Q06787
NG_007529.2
PubMed
0   ANCO-SNPs
ND|AD
6   
NA (AD)  NA (ND)   (Frontal_Cortex)
NA (AD)  NA (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
EPS150.937
SERINC10.935
RNF110.927
TOP2B0.926
PCNP0.916
PRKAR1A0.915
BTBD10.91
RPRD1A0.91
RNF140.909
MATR30.908

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
OR4F29-0.758
OR4F5-0.751
MTRNR2L10-0.246
CSAG1-0.242
MTRNR2L6-0.227
MTRNR2L3-0.227
SPINK8-0.207
MTRNR2L9-0.206
MTRNR2L2-0.203
MTRNR2L8-0.2

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C0703791,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester"1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [3,5-dihydroxyphenylglycine affects the localization of FMR1 mRNA]"15028757
C0703791,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester"1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [3,5-dihydroxyphenylglycine affects the localization of FMR1 protein]"15028757
C0164032,4-dinitrotoluene"2,4-dinitrotoluene affects the expression of FMR1 mRNA"21346803
C0792153,5-dihydroxyphenylglycine"3,5-dihydroxyphenylglycine inhibits the reaction [FMR1 gene mutant form results in increased activity of MGLL]"20393458
C0792153,5-dihydroxyphenylglycine"1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [3,5-dihydroxyphenylglycine affects the localization of FMR1 mRNA]"15028757
C0792153,5-dihydroxyphenylglycine"1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [3,5-dihydroxyphenylglycine affects the localization of FMR1 protein]"15028757
C0792153,5-dihydroxyphenylglycine"3,5-dihydroxyphenylglycine affects the localization of FMR1 mRNA"15028757
C0792153,5-dihydroxyphenylglycine"3,5-dihydroxyphenylglycine affects the localization of FMR1 protein"15028757
C0792153,5-dihydroxyphenylglycine"Ro 32-0432 inhibits the reaction [3,5-dihydroxyphenylglycine affects the localization of FMR1 mRNA]"15028757
C0792153,5-dihydroxyphenylglycine"Ro 32-0432 inhibits the reaction [3,5-dihydroxyphenylglycine affects the localization of FMR1 protein]"15028757
C0126064-vinyl-1-cyclohexene dioxide4-vinyl-1-cyclohexene dioxide affects the expression of FMR1 mRNA20829426
C0106436-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid"6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [FMR1 5' UTR mutant form results in decreased activity of CS protein]"27385396
C1214656-methyl-2-(phenylethynyl)pyridineFMR1 gene mutant form promotes the reaction [6-methyl-2-(phenylethynyl)pyridine binds to GRM5 protein]20393458
C1214656-methyl-2-(phenylethynyl)pyridine6-methyl-2-(phenylethynyl)pyridine inhibits the reaction [Potassium Chloride affects the localization of FMR1 protein]15028757
C043877acamprosateacamprosate inhibits the reaction [FMR1 protein affects the phosphorylation of MAPK1 protein]28616095
C043877acamprosateacamprosate inhibits the reaction [FMR1 protein affects the phosphorylation of MAPK3 protein]28616095
D000111AcetylcysteineAcetylcysteine promotes the reaction [FMR1 5' UTR mutant form results in decreased activity of CS protein]27385396
D020106AcrylamideAcrylamide results in increased expression of FMR1 mRNA28959563
D016604Aflatoxin B1Aflatoxin B1 results in decreased methylation of FMR1 gene27153756
C019249aminomalonic acidFMR1 5' UTR mutant form results in increased abundance of aminomalonic acid27385396
C015001arsenitearsenite affects the localization of FMR1 protein16510718
D001205Ascorbic AcidAscorbic Acid inhibits the reaction [FMR1 5' UTR mutant form results in decreased activity of CS protein]27385396
C030935benz(a)anthracene[Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of FMR1 mRNA27858113
C006703benzo(b)fluoranthene[Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of FMR1 mRNA27858113
C006703benzo(b)fluoranthenebenzo(b)fluoranthene results in decreased expression of FMR1 mRNA26377693
D001564Benzo(a)pyrene[Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of FMR1 mRNA27858113
C006780bisphenol Abisphenol A affects the expression of FMR1 mRNA21786754
C006780bisphenol Abisphenol A results in decreased expression of FMR1 mRNA23719926
C006780bisphenol Abisphenol A affects the expression of FMR1 mRNA25181051
D000069286BortezomibBortezomib results in decreased expression of FMR1 mRNA17659339
D002259Carbonyl Cyanide p-TrifluoromethoxyphenylhydrazoneCarbonyl Cyanide p-Trifluoromethoxyphenylhydrazone inhibits the reaction [FMR1 5' UTR mutant form results in increased abundance of Hydroxyl Radical]27385396
D002259Carbonyl Cyanide p-TrifluoromethoxyphenylhydrazoneCarbonyl Cyanide p-Trifluoromethoxyphenylhydrazone inhibits the reaction [FMR1 5' UTR mutant form results in increased abundance of Superoxides]27385396
C031180chrysene[Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of FMR1 mRNA27858113
D003042CocaineCocaine results in decreased expression of FMR1 mRNA24810662
D019327Copper SulfateCopper Sulfate results in decreased expression of FMR1 mRNA19549813
C029892cupric chloridecupric chloride results in decreased expression of FMR1 protein22699969
D003513Cycloheximide[Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of FMR1 mRNA19684285
D016572CyclosporineCyclosporine results in decreased expression of FMR1 mRNA25562108
D003907DexamethasoneDexamethasone inhibits the reaction [RX3 gene mutant form affects the expression of FMR1 mRNA]27941970
D003993Dibutyl Phthalate[Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of FMR1 mRNA25607892
D003633Dichlorodiphenyl Dichloroethylene[Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of FMR1 mRNA25607892
D004041Dietary FatsDietary Fats results in increased expression of FMR1 mRNA19030233
D004041Dietary Fatsrimonabant inhibits the reaction [Dietary Fats results in increased expression of FMR1 mRNA]19030233
D004051Diethylhexyl Phthalate[Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of FMR1 mRNA25607892
D004121Dimethyl SulfoxideDimethyl Sulfoxide inhibits the reaction [FMR1 5' UTR mutant form results in decreased activity of CS protein]27385396
D004221DisulfiramDisulfiram results in decreased expression of FMR1 mRNA20530235
C042986ebselenebselen inhibits the reaction [FMR1 5' UTR mutant form results in decreased activity of CS protein]27385396
C109476epoxiconazole[Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of FMR1 mRNA25607892
D000431EthanolEthanol promotes the reaction [FMR1 5' UTR mutant form results in decreased activity of CS protein]27385396
C039281furanfuran results in decreased expression of FMR1 mRNA25539665
C094503glyceryl 2-arachidonate[FMR1 gene mutant form results in increased activity of MGLL] which results in increased degradation of glyceryl 2-arachidonate20393458
D006603Hexuronic AcidsFMR1 5' UTR mutant form results in increased abundance of Hexuronic Acids27385396
D017313FenretinideFenretinide results in decreased expression of FMR1 mRNA28973697
D017665Hydroxyl RadicalCarbonyl Cyanide p-Trifluoromethoxyphenylhydrazone inhibits the reaction [FMR1 5' UTR mutant form results in increased abundance of Hydroxyl Radical]27385396
D017665Hydroxyl RadicalFMR1 5' UTR mutant form results in increased abundance of Hydroxyl Radical27385396
D015759Ionomycin[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of FMR1 mRNA25613284
C410337K 7174K 7174 results in increased expression of FMR1 mRNA24086573
D048628KetolidesKetolides analog results in increased expression of FMR1 mRNA24967691
D008044Linuron[Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of FMR1 mRNA25607892
C097284manganese(III)-tetrakis(4-benzoic acid)porphyrinmanganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [FMR1 5' UTR mutant form results in decreased activity of CS protein]27385396
D008731MethoxychlorMethoxychlor affects the expression of FMR1 mRNA20829426
C474696methyl-(4-carboxyphenyl)glycinemethyl-(4-carboxyphenyl)glycine inhibits the reaction [Potassium Chloride affects the localization of FMR1 protein]15028757
D008767Methylmercury CompoundsMethylmercury Compounds results in increased expression of FMR1 protein26558463
D018817N-Methyl-3,4-methylenedioxyamphetamine"N-Methyl-3,4-methylenedioxyamphetamine results in decreased expression of FMR1 mRNA"26251327
D0156551-Methyl-4-phenylpyridinium1-Methyl-4-phenylpyridinium results in increased expression of FMR1 protein26558463
D008911MinocyclineMinocycline inhibits the reaction [FMR1 gene mutant form results in increased expression of and results in increased activity of MMP9 protein]18835858
C029938nickel sulfatenickel sulfate results in decreased expression of FMR1 mRNA22714537
D010416PentachlorophenolPentachlorophenol results in increased expression of FMR1 mRNA23892564
C076994perfluorooctane sulfonic acidperfluorooctane sulfonic acid results in decreased expression of FMR1 mRNA27153767
D010672PhenytoinPhenytoin results in increased expression of FMR1 mRNA20345932
D010936Plant ExtractsPlant Extracts results in increased expression of FMR1 mRNA23557933
D011070Poly I-CPoly I-C results in decreased expression of FMR1 protein23516405
D011070Poly I-CSuramin inhibits the reaction [Poly I-C results in decreased expression of FMR1 protein]23516405
D011189Potassium Chloride6-methyl-2-(phenylethynyl)pyridine inhibits the reaction [Potassium Chloride affects the localization of FMR1 protein]15028757
D011189Potassium Chloridemethyl-(4-carboxyphenyl)glycine inhibits the reaction [Potassium Chloride affects the localization of FMR1 protein]15028757
D011189Potassium ChloridePotassium Chloride affects the localization of FMR1 mRNA15028757
D011189Potassium ChloridePotassium Chloride affects the localization of FMR1 protein15028757
C027373potassium chromate(VI)potassium chromate(VI) results in decreased expression of FMR1 mRNA22714537
C045362prochloraz[Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of FMR1 mRNA25607892
C035988procymidone[Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of FMR1 mRNA25607892
D011794QuercetinQuercetin results in decreased expression of FMR1 mRNA21632981
C059514resveratrolresveratrol results in decreased expression of FMR1 mRNA25905778
C089032rimonabantrimonabant inhibits the reaction [Dietary Fats results in increased expression of FMR1 mRNA]19030233
C085989Ro 32-0432"Ro 32-0432 inhibits the reaction [3,5-dihydroxyphenylglycine affects the localization of FMR1 mRNA]"15028757
C085989Ro 32-0432"Ro 32-0432 inhibits the reaction [3,5-dihydroxyphenylglycine affects the localization of FMR1 protein]"15028757
D013012SorbitolFMR1 5' UTR mutant form results in increased abundance of Sorbitol27385396
D013481SuperoxidesCarbonyl Cyanide p-Trifluoromethoxyphenylhydrazone inhibits the reaction [FMR1 5' UTR mutant form results in increased abundance of Superoxides]27385396
D013481SuperoxidesFMR1 5' UTR mutant form results in increased abundance of Superoxides27385396
D013498SuraminSuramin inhibits the reaction [Poly I-C results in decreased expression of FMR1 protein]23516405
D013629TamoxifenTamoxifen results in decreased expression of FMR1 mRNA17555576
D013749Tetrachlorodibenzodioxin[Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of FMR1 mRNA19684285
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of FMR1 mRNA19684285
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased expression of FMR1 mRNA19933214
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of FMR1 mRNA26232522
D013755Tetradecanoylphorbol Acetate[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of FMR1 mRNA25613284
C014215tetrahydropalmatinetetrahydropalmatine results in decreased expression of FMR1 protein20109541
D013893ThiramThiram results in decreased expression of FMR1 mRNA20530235
C003460threitolFMR1 5' UTR mutant form results in increased abundance of threitol27385396
C011369threonic acidFMR1 5' UTR mutant form results in increased abundance of threonic acid27385396
D014212TretinoinTretinoin results in increased expression of FMR1 mRNA28689802
C012589trichostatin Atrichostatin A results in increased expression of FMR1 mRNA24935251
D014520UrethaneUrethane results in increased expression of FMR1 mRNA28818685
D014638VanadatesVanadates results in increased expression of FMR1 mRNA22714537
D001335Vehicle EmissionsVehicle Emissions results in decreased methylation of FMR1 gene25560391
D020888VigabatrinVigabatrin results in increased expression of FMR1 protein21490592
C025643vinclozolin[Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of FMR1 mRNA25607892
D024483Vitamin K 3Vitamin K 3 affects the expression of FMR1 mRNA20829426
D015032ZincZinc results in decreased expression of FMR1 mRNA20932299

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0002151G-quadruplex RNA binding-IDA18653529  25464849  
GO:0003682chromatin binding-ISS-  
GO:0003723RNA binding-HDA22658674  22681889  
GO:0003723RNA binding-IDA15381419  
GO:0003723RNA binding-IMP10496225  25225333  
GO:0003729mRNA binding-IBA21873635  
GO:0003729mRNA binding-IDA11157796  18936162  25561520  
GO:0003730mRNA 3'-UTR binding-IBA21873635  
GO:0003730mRNA 3'-UTR binding-IDA17417632  
GO:0005515protein binding-IPI7489725  10556305  11157796  11438699  12837692  15380484  
15381419  16407062  16571602  18093976  18936162  21771594  
24514761  24658146  25225333  25464849  
GO:0008017microtubule binding-ISS-  
GO:0008266poly(U) RNA binding-IDA7688265  8156595  
GO:0030371translation repressor activity-IDA11157796  
GO:0031369translation initiation factor binding-IPI24658146  
GO:0033592RNA strand annealing activity-IDA17057366  
GO:0034046poly(G) binding-IDA7688265  
GO:0035064methylated histone binding-IDA24813610  
GO:0035197siRNA binding-IDA17057366  
GO:0035198miRNA binding-IDA17057366  
GO:0035613RNA stem-loop binding-IDA15805463  19166269  
GO:0042802identical protein binding-IDA11157796  
GO:0042802identical protein binding-IPI17850748  21446998  
GO:0042803protein homodimerization activity-IBA21873635  
GO:0042803protein homodimerization activity-IDA7489725  
GO:0043022ribosome binding-IPI24658146  
GO:0044325ion channel binding-IPI25561520  
GO:0045182translation regulator activity-IBA21873635  
GO:0046982protein heterodimerization activity-IDA7489725  
GO:0048027mRNA 5'-UTR binding-IDA19166269  
GO:0070840dynein complex binding-ISS-  
GO:1990825sequence-specific mRNA binding-IDA12927206  23235829  
GO ID GO Term Qualifier Evidence PubMed
GO:0000381regulation of alternative mRNA splicing, via spliceosome-IBA21873635  
GO:0000381regulation of alternative mRNA splicing, via spliceosome-IDA18653529  
GO:0001934positive regulation of protein phosphorylation-IBA21873635  
GO:0002092positive regulation of receptor internalization-IDA25561520  
GO:0006397mRNA processing-IEA-  
GO:0006974cellular response to DNA damage stimulus-IDA24813610  
GO:0007215glutamate receptor signaling pathway-ISS-  
GO:0007417central nervous system development-IBA21873635  
GO:0008089anterograde axonal transport-IBA21873635  
GO:0008380RNA splicing-IEA-  
GO:0016032viral process-IEA-  
GO:0017148negative regulation of translation-IBA21873635  
GO:0031047gene silencing by RNA-IEA-  
GO:0033129positive regulation of histone phosphorylation-IDA24813610  
GO:0034644cellular response to UV-ISS-  
GO:0043488regulation of mRNA stability-IBA21873635  
GO:0043488regulation of mRNA stability-ISS-  
GO:0044830modulation by host of viral RNA genome replication-IMP24514761  
GO:0045727positive regulation of translation-IBA21873635  
GO:0045727positive regulation of translation-IDA19097999  19166269  
GO:0045947negative regulation of translational initiation-ISS-  
GO:0046928regulation of neurotransmitter secretion-ISS-  
GO:0048666neuron development-IBA21873635  
GO:0048814regulation of dendrite morphogenesis-IBA21873635  
GO:0051028mRNA transport-ISS-  
GO:0051489regulation of filopodium assembly-IBA21873635  
GO:0051489regulation of filopodium assembly-IDA16631377  
GO:0051491positive regulation of filopodium assembly-ISS-  
GO:0060964regulation of gene silencing by miRNA-IMP25464849  
GO:0060998regulation of dendritic spine development-IBA21873635  
GO:0060998regulation of dendritic spine development-IDA16631377  
GO:0060999positive regulation of dendritic spine development-ISS-  
GO:0072711cellular response to hydroxyurea-ISS-  
GO:0098586cellular response to virus-IDA24514761  
GO:0098908regulation of neuronal action potential-IDA25561520  
GO:0099578regulation of translation at postsynapse, modulating synaptic transmission-IBA21873635  
GO:1900453negative regulation of long term synaptic depression-ISS-  
GO:1901254positive regulation of intracellular transport of viral material-IMP24514761  
GO:1901386negative regulation of voltage-gated calcium channel activity-ISS-  
GO:1901800positive regulation of proteasomal protein catabolic process-ISS-  
GO:1902373negative regulation of mRNA catabolic process-IMP25225333  
GO:1902416positive regulation of mRNA binding-IDA25464849  
GO:1905244regulation of modification of synaptic structure-IBA21873635  
GO:2000301negative regulation of synaptic vesicle exocytosis-ISS-  
GO:2000637positive regulation of gene silencing by miRNA-IDA17057366  
GO:2000766negative regulation of cytoplasmic translation-ISS-  
GO:2001022positive regulation of response to DNA damage stimulus-IBA21873635  
GO:2001022positive regulation of response to DNA damage stimulus-IDA24813610  
GO ID GO Term Qualifier Evidence PubMed
GO:0000775chromosome, centromeric region-IEA-  
GO:0005634nucleus-IBA21873635  
GO:0005634nucleus-IDA18936162  
GO:0005634nucleus-ISS-  
GO:0005654nucleoplasm-IDA16571602  
GO:0005694chromosome-ISS-  
GO:0005730nucleolus-IDA16571602  24658146  
GO:0005730nucleolus-TAS16407062  
GO:0005737cytoplasm-IBA21873635  
GO:0005737cytoplasm-IDA9659908  15381419  16571602  18936162  
GO:0005737cytoplasm-TAS16407062  
GO:0005829cytosol-IDA-  
GO:0005844polysome-IBA21873635  
GO:0005844polysome-IDA9659908  19097999  25464849  25561520  
GO:0005844polysome-ISS-  
GO:0005845mRNA cap binding complex-ISS-  
GO:0010369chromocenter-ISS-  
GO:0010494cytoplasmic stress granule-IEA-  
GO:0014069postsynaptic density-IBA21873635  
GO:0014069postsynaptic density-ISS-  
GO:0015030Cajal body-IEA-  
GO:0016020membrane-HDA19946888  
GO:0016020membrane-IBA21873635  
GO:0019034viral replication complex-IDA24514761  
GO:0019897extrinsic component of plasma membrane-ISS-  
GO:0030054cell junction-IEA-  
GO:0030424axon-IBA21873635  
GO:0030424axon-ISS-  
GO:0030425dendrite-ISS-  
GO:0030426growth cone-IBA21873635  
GO:0030426growth cone-IDA15380484  
GO:0032433filopodium tip-ISS-  
GO:0032797SMN complexcolocalizes_withIDA18093976  
GO:0035770ribonucleoprotein granule-IBA21873635  
GO:0036464cytoplasmic ribonucleoprotein granule-IBA21873635  
GO:0036464cytoplasmic ribonucleoprotein granule-IDA15121898  15380484  18093976  
GO:0042734presynaptic membrane-IEA-  
GO:0042788polysomal ribosomecolocalizes_withTAS12837692  
GO:0042995cell projection-IDA15380484  
GO:0043005neuron projection-IDA18093976  
GO:0043025neuronal cell body-IBA21873635  
GO:0043197dendritic spine-IBA21873635  
GO:0043197dendritic spine-ISS-  
GO:0043204perikaryon-IDA15380484  18093976  
GO:0043204perikaryon-ISS-  
GO:0043679axon terminus-ISS-  
GO:0044295axonal growth cone-IBA21873635  
GO:0044326dendritic spine neck-IBA21873635  
GO:0045202synapse-ISS-  
GO:0045211postsynaptic membrane-IEA-  
GO:0048471perinuclear region of cytoplasm-IDA24658146  
GO:0071598neuronal ribonucleoprotein granule-IBA21873635  
GO:0071598neuronal ribonucleoprotein granule-ISS-  
GO:0097386glial cell projection-ISS-  
GO:0098793presynapse-IBA21873635  
GO:0098793presynapse-ISS-  
GO:0098794postsynapse-ISS-  
GO:1902737dendritic filopodium-IBA21873635  
GO:1902737dendritic filopodium-ISS-  
GO:1990124messenger ribonucleoprotein complex-IDA25225333  
GO:1990812growth cone filopodium-ISS-  
GO:1990904ribonucleoprotein complex-IDA9659908  19097999  
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
18357616Fragile X-associated primary ovarian insufficiency: evidence for additional genetic contributions to severity. (2008 Sep)Hunter JEGenet Epidemiol
28616095Acamprosate in a mouse model of fragile X syndrome: modulation of spontaneous cortical activity, ERK1/2 activation, locomotor behavior, and anxiety. (2017)Schaefer TLJ Neurodev Disord
24779259Premature ovarian failure in a 17-year-old woman. (2014)Caserta DClin Exp Obstet Gynecol
23079771Olfactory dysfunction in fragile X tremor ataxia syndrome. (2012 Oct)Juncos JLMov Disord
17588953Examination of reproductive aging milestones among women who carry the FMR1 premutation. (2007 Aug)Allen EGHum Reprod
21969264FMR1 and the continuum of primary ovarian insufficiency. (2011 Jul)Sullivan SDSemin Reprod Med