Gene: TRIM29

23650
ATDC
tripartite motif containing 29
protein-coding
11q23.3
Ensembl:ENSG00000137699 MIM:610658 Vega:OTTHUMG00000140377 UniprotKB:Q14134
NC_000011.10
PubMed
0   ANCO-SNPs
ND
1   
NA (AD)  NA (ND)   (Frontal_Cortex)
9.008e-2 (AD)  4.435e-1 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
KRT140.703
LAD10.666
KRT10.639
LGALS7B0.637
KLK110.634
SERPINB50.633
TACSTD20.628
DSC30.627
TNS40.626
ALDH3B20.617

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
GAGE10-0.292
FAM151A-0.239
RIPPLY3-0.217
CPSF4L-0.216
LTA-0.209
SNX31-0.209
HSPB9-0.209
KLKB1-0.207
SLC25A31-0.204
DMRTC1B-0.204

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C02017516 alpha-ethyl-21-hydroxy-19-nor-4-pregnene-3,20-dione"16 alpha-ethyl-21-hydroxy-19-nor-4-pregnene-3,20-dione results in increased expression of TRIM29 mRNA"20519331
C5112952,2',4,4'-tetrabromodiphenyl ether"2,2',4,4'-tetrabromodiphenyl ether results in decreased expression of TRIM29 mRNA"27291303
D020106AcrylamideAcrylamide affects the expression of TRIM29 mRNA28959563
D016604Aflatoxin B1Aflatoxin B1 results in increased expression of TRIM29 mRNA21641981|2210060
D001151ArsenicArsenic results in increased methylation of TRIM29 promoter21291286
D004958EstradiolEstradiol results in increased expression of TRIM29 mRNA19484750
C006780bisphenol Abisphenol A results in decreased expression of TRIM29 mRNA25181051
D002794Choline[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of TRIM29 mRNA20938992
D003300Copper[Copper co-treated with Dietary Sucrose] results in increased expression of TRIM29 mRNA26033743
D003300CopperCopper deficiency results in increased expression of TRIM29 mRNA26033743
D003703DemecolcineDemecolcine results in increased expression of TRIM29 mRNA23649840
D019422Dietary Sucrose[Copper co-treated with Dietary Sucrose] results in increased expression of TRIM29 mRNA26033743
D019422Dietary SucroseDietary Sucrose results in increased expression of TRIM29 mRNA26033743
D002117CalcitriolCalcitriol results in increased expression of TRIM29 mRNA26485663
D005492Folic Acid[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of TRIM29 mRNA20938992
D005557FormaldehydeFormaldehyde results in increased expression of TRIM29 mRNA23649840
D017313FenretinideFenretinide results in decreased expression of TRIM29 mRNA28973697
D058185Magnetite Nanoparticles[Succimer co-treated with Magnetite Nanoparticles] results in increased expression of TRIM29 mRNA26378955
D008715Methionine[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of TRIM29 mRNA20938992
D037742Nanotubes, Carbon"Nanotubes, Carbon analog results in increased expression of TRIM29 mRNA"25554681
C029938nickel sulfatenickel sulfate results in increased expression of TRIM29 mRNA18651567
C558013NSC 689534NSC 689534 results in increased expression of TRIM29 mRNA20971185
C076994perfluorooctane sulfonic acidperfluorooctane sulfonic acid results in decreased expression of TRIM29 mRNA27153767
C023036perfluorooctanoic acidperfluorooctanoic acid results in decreased expression of TRIM29 mRNA27153767
D012643Selenium[Selenium co-treated with Vitamin E] results in increased expression of TRIM29 mRNA19244175
D012643SeleniumSelenium results in increased expression of TRIM29 mRNA19244175
D012822Silicon DioxideSilicon Dioxide analog results in decreased expression of TRIM29 mRNA25895662
D012906SmokeSmoke results in decreased expression of TRIM29 mRNA21095227
C017947sodium arsenitesodium arsenite affects the methylation of TRIM29 gene28589171
D004113Succimer[Succimer co-treated with Magnetite Nanoparticles] results in increased expression of TRIM29 mRNA26378955
C009495titanium dioxidetitanium dioxide results in increased expression of TRIM29 mRNA27760801
C024746tobacco tartobacco tar results in decreased expression of TRIM29 mRNA19559774
D014112ToxapheneToxaphene results in decreased expression of TRIM29 mRNA23153324
D014212TretinoinTretinoin results in decreased expression of TRIM29 mRNA23830798
D014635Valproic AcidValproic Acid results in increased methylation of TRIM29 gene29154799
D014635Valproic AcidValproic Acid affects the expression of TRIM29 mRNA17292431|1796380
D014750VincristineVincristine results in increased expression of TRIM29 mRNA23649840
D014810Vitamin E[Selenium co-treated with Vitamin E] results in increased expression of TRIM29 mRNA19244175

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0002039p53 binding-IEA-  
GO:0003700DNA-binding transcription factor activity-TAS8188213  
GO:0005515protein binding-IPI16189514  19249679  21516116  25416956  
GO:0008270zinc ion binding-IEA-  
GO:0042802identical protein binding-IPI16189514  
GO:0098641cadherin binding involved in cell-cell adhesion-HDA25468996  
GO ID GO Term Qualifier Evidence PubMed
GO:0000122negative regulation of transcription by RNA polymerase II-IEA-  
GO:0006366transcription by RNA polymerase II-TAS8188213  
GO:0045087innate immune response-IEA-  
GO:0098609cell-cell adhesion-IEA-  
GO:1900181negative regulation of protein localization to nucleus-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO:0005764lysosome-IEA-  
GO:0005913cell-cell adherens junction-HDA25468996  
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence
R-HSA-1280215Cytokine Signaling in Immune systemTAS
R-HSA-168256Immune SystemTAS
R-HSA-877300Interferon gamma signalingTAS
R-HSA-913531Interferon SignalingTAS

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
26622835Tripartite motif-containing 29 as a novel biomarker in non-small cell lung cancer. (2015 Oct)Song XOncol Lett