Gene info: ID 2492

Gene: FSHR

GENE ID: 2492

Synonyms: FSHR1|FSHRO|LGR1|ODG1

Description: follicle stimulating hormone receptor

Gene type: protein-coding

Location: 2p16.3

dbXrefs: Ensembl:ENSG00000170820 MIM:136435 Vega:OTTHUMG00000129259 UniprotKB:P23945

RefSeq: NG_008146.1

Retrived from: PubMed

SNPs: 1 ANCO-SNPs

Phenotype: ND

# Publications: 3

Sherlock p-value : NA (AD) NA (ND) (Frontal_Cortex)

Pascal p-value : 5.439e-1 (AD) 1.522e-1 (ND)

ANCO-SNPs

SNP ID	Position	Alleles	Trait	Variation Type
rs989373	chr2:48931186 (GRCh38.p7)	T>C	alcohol dependence	SNV(Single Nucleotide Variation)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol	Pearson Correlation Coefficient
PLCXD2	0.61
KCNH5	0.578
DCC	0.558
PCDHAC2	0.524
PCDHA5	0.524
PPM1E	0.519
KCNH1	0.519
FMN1	0.512
GRM5	0.512
RET	0.511

Top 10 negatively co-expressed genes

Gene Symbol	Pearson Correlation Coefficient
RBP1	-0.368
BCL7C	-0.364
COPZ2	-0.358
S100A1	-0.349
TIMP4	-0.339
NFIA	-0.332
OLIG1	-0.326
SNX22	-0.325
SOX3	-0.318
S100A13	-0.317

ID	Drug Name	Drug Type	CAS Num	Status	Role
DB00032	Menotropins	BiotechDrug	9002-68-0	Approved	Target
DB00066	Follitropin	BiotechDrug	146479-72-3	Approved	Target
DB00094	Urofollitropin	BiotechDrug	97048-13-0	Approved	Target
DB00097	Choriogonadotropin alfa	BiotechDrug	177073-44-8	Approved	Target
DB04786	Suramin	Small Molecule	145-63-1	Approved\|Investigational	Target

ID	Drug Name	Action	PubMed
C016392	3,3'-diindolylmethane	"3,3'-diindolylmethane results in increased expression of FSHR mRNA"	27092574
C583074	4,4'-hexafluorisopropylidene diphenol	"4,4'-hexafluorisopropylidene diphenol results in increased expression of FSHR mRNA"	25723718
C116322	4-benzhydryloxy-1-(3-(1H-tetrazol-5-yl-)-propyl)piperidine	4-benzhydryloxy-1-(3-(1H-tetrazol-5-yl-)-propyl)piperidine inhibits the reaction [CGA protein results in increased expression of FSHR mRNA]	21352547
C116322	4-benzhydryloxy-1-(3-(1H-tetrazol-5-yl-)-propyl)piperidine	4-benzhydryloxy-1-(3-(1H-tetrazol-5-yl-)-propyl)piperidine results in decreased expression of FSHR mRNA	21352547
D000082	Acetaminophen	Acetaminophen affects the expression of FSHR mRNA	17562736
D000242	Cyclic AMP	Benzo(a)pyrene inhibits the reaction [[FSHB protein results in increased activity of FSHR protein] which results in increased abundance of Cyclic AMP]	26895433
D000242	Cyclic AMP	[CGA protein results in increased activity of FSHR protein] which results in increased abundance of Cyclic AMP	26895433
D000242	Cyclic AMP	DDT promotes the reaction [[CGA protein results in increased activity of FSHR protein] which results in increased abundance of Cyclic AMP]	26895433
D000242	Cyclic AMP	DDT promotes the reaction [[FSHB protein results in increased activity of FSHR protein] which results in increased abundance of Cyclic AMP]	26895433
D000242	Cyclic AMP	Dichlorodiphenyl Dichloroethylene promotes the reaction [[FSHB protein results in increased activity of FSHR protein] which results in increased abundance of Cyclic AMP]	26895433
D000242	Cyclic AMP	[FSHB protein results in increased activity of FSHR protein] which results in increased abundance of Cyclic AMP	26895433
D000242	Cyclic AMP	"o,p'-DDT promotes the reaction [[FSHB protein results in increased activity of FSHR protein] which results in increased abundance of Cyclic AMP]"	26895433
D016604	Aflatoxin B1	Aflatoxin B1 results in decreased methylation of FSHR gene	27153756
D013196	Dihydrotestosterone	bicalutamide inhibits the reaction [Dihydrotestosterone results in increased expression of FSHR mRNA]	16641147
D013196	Dihydrotestosterone	[Dihydrotestosterone co-treated with Colforsin] results in increased expression of FSHR mRNA	16641147
D013196	Dihydrotestosterone	[Dihydrotestosterone co-treated with Estradiol co-treated with Colforsin] results in increased expression of FSHR mRNA	16641147
D013196	Dihydrotestosterone	[Dihydrotestosterone co-treated with Estradiol co-treated with FSHB protein] results in increased expression of FSHR mRNA	16641147
D013196	Dihydrotestosterone	[Dihydrotestosterone co-treated with Estradiol] results in increased expression of FSHR mRNA	16641147
D013196	Dihydrotestosterone	[Dihydrotestosterone co-treated with FSHB protein] results in increased expression of FSHR mRNA	16641147
D013196	Dihydrotestosterone	Dihydrotestosterone results in increased expression of FSHR mRNA	16641147
C011512	alpha-naphthoflavone	alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of FSHR protein]	20823264
D000643	Ammonium Chloride	Ammonium Chloride affects the expression of FSHR mRNA	16483693
D001205	Ascorbic Acid	Ascorbic Acid inhibits the reaction [chromium hexavalent ion results in decreased expression of FSHR mRNA]	18602937
D001205	Ascorbic Acid	Ascorbic Acid inhibits the reaction [Potassium Dichromate results in decreased expression of FSHR mRNA]	23470461
D001205	Ascorbic Acid	Ascorbic Acid inhibits the reaction [Potassium Dichromate results in decreased expression of FSHR protein]	23470461
D001564	Benzo(a)pyrene	Benzo(a)pyrene inhibits the reaction [[FSHB protein results in increased activity of FSHR protein] which results in increased abundance of Cyclic AMP]	26895433
D001564	Benzo(a)pyrene	Benzo(a)pyrene results in decreased expression of FSHR mRNA	21839799
D004958	Estradiol	[Dihydrotestosterone co-treated with Estradiol co-treated with Colforsin] results in increased expression of FSHR mRNA	16641147
D004958	Estradiol	[Dihydrotestosterone co-treated with Estradiol co-treated with FSHB protein] results in increased expression of FSHR mRNA	16641147
D004958	Estradiol	[Dihydrotestosterone co-treated with Estradiol] results in increased expression of FSHR mRNA	16641147
C053541	bicalutamide	bicalutamide inhibits the reaction [Dihydrotestosterone results in increased expression of FSHR mRNA]	16641147
C053541	bicalutamide	bicalutamide inhibits the reaction [Testosterone results in increased expression of FSHR mRNA]	16641147
C006780	bisphenol A	bisphenol A results in increased expression of FSHR mRNA	26911650
C006780	bisphenol A	"bisphenol A promotes the reaction [[Gonadotropins, Equine co-treated with Chorionic Gonadotropin] results in increased expression of FSHR mRNA]"	28648634
C006780	bisphenol A	bisphenol A results in increased expression of FSHR mRNA	26746108
C006780	bisphenol A	bisphenol A affects the expression of FSHR mRNA	25181051
C006780	bisphenol A	"bisphenol A promotes the reaction [Gonadotropins, Equine results in increased expression of FSHR mRNA]"	28648634
C006780	bisphenol A	bisphenol A results in increased expression of FSHR mRNA	26658420\|2835569
C006780	bisphenol A	bisphenol A results in increased expression of FSHR protein	28355696
C000611646	bisphenol F	bisphenol F results in increased expression of FSHR mRNA	28741210
D001761	Bleomycin	Bleomycin results in decreased expression of FSHR mRNA	15808516
C027561	butylbenzyl phthalate	[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of FSHR mRNA	28013214
D019256	Cadmium Chloride	Cadmium Chloride results in decreased methylation of FSHR promoter	22457795
C010059	carbamylhydrazine	carbamylhydrazine analog results in decreased expression of FSHR mRNA	28834696
C074702	chromium hexavalent ion	Ascorbic Acid inhibits the reaction [chromium hexavalent ion results in decreased expression of FSHR mRNA]	18602937
C074702	chromium hexavalent ion	chromium hexavalent ion results in decreased expression of FSHR mRNA	18602937\|2162160
D003022	Clotrimazole	Clotrimazole results in increased expression of FSHR mRNA	22564764
D005576	Colforsin	[Dihydrotestosterone co-treated with Colforsin] results in increased expression of FSHR mRNA	16641147
D005576	Colforsin	[Dihydrotestosterone co-treated with Estradiol co-treated with Colforsin] results in increased expression of FSHR mRNA	16641147
D065366	Cryptoxanthins	Cryptoxanthins inhibits the reaction [Lipopolysaccharides results in decreased expression of FSHR mRNA]	26686910
D065366	Cryptoxanthins	Cryptoxanthins results in increased expression of FSHR mRNA	26686910
D003484	Cyanamide	Cyanamide inhibits the reaction [CGA protein results in increased expression of FSHR mRNA]	22285649
C017160	cypermethrin	[cypermethrin co-treated with Diethylhexyl Phthalate] results in decreased expression of FSHR mRNA	24641848
D003634	DDT	DDT promotes the reaction [[CGA protein results in increased activity of FSHR protein] which results in increased abundance of Cyclic AMP]	26895433
D003634	DDT	DDT promotes the reaction [[FSHB protein results in increased activity of FSHR protein] which results in increased abundance of Cyclic AMP]	26895433
D003634	DDT	DDT affects the activity of FSHR protein	17157474
D003634	DDT	DDT inhibits the reaction [FSHB protein binds to FSHR protein]	17157474
D003634	DDT	DDT results in decreased activity of FSHR protein	26895433
D003993	Dibutyl Phthalate	[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of FSHR mRNA	28013214
D002945	Cisplatin	Cisplatin results in decreased expression of FSHR mRNA	23956100
D003633	Dichlorodiphenyl Dichloroethylene	Dichlorodiphenyl Dichloroethylene promotes the reaction [[FSHB protein results in increased activity of FSHR protein] which results in increased abundance of Cyclic AMP]	26895433
D003633	Dichlorodiphenyl Dichloroethylene	Dichlorodiphenyl Dichloroethylene results in decreased expression of FSHR protein	23501609
D003633	Dichlorodiphenyl Dichloroethylene	Dichlorodiphenyl Dichloroethylene results in increased expression of FSHR mRNA	23501609
D004051	Diethylhexyl Phthalate	Diethylhexyl Phthalate results in decreased expression of FSHR mRNA	27417426\|2828611
D004051	Diethylhexyl Phthalate	[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of FSHR mRNA	28013214
D004051	Diethylhexyl Phthalate	[cypermethrin co-treated with Diethylhexyl Phthalate] results in decreased expression of FSHR mRNA	24641848
D004051	Diethylhexyl Phthalate	Diethylhexyl Phthalate results in decreased expression of FSHR mRNA	24641848
D004051	Diethylhexyl Phthalate	Diethylhexyl Phthalate results in decreased expression of FSHR protein	24641848
C007379	diethyl phthalate	[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of FSHR mRNA	28013214
D004054	Diethylstilbestrol	Diethylstilbestrol promotes the reaction [FSHB protein results in increased expression of FSHR mRNA]	15878960
C025605	diisobutyl phthalate	[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of FSHR mRNA	28013214
C012125	diisononyl phthalate	[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of FSHR mRNA	28013214
D004221	Disulfiram	Disulfiram inhibits the reaction [[FSHB protein co-treated with LHB protein co-treated with Testosterone] results in increased expression of FSHR mRNA]	22285649
D004317	Doxorubicin	Doxorubicin results in decreased expression of FSHR mRNA	23956100
D004997	Ethinyl Estradiol	Ethinyl Estradiol results in decreased expression of FSHR mRNA	12655037
D005038	Ethylnitrosourea	Ethylnitrosourea results in increased mutagenesis of FSHR gene	16495775
D017316	Fadrozole	Fadrozole affects the expression of FSHR mRNA	25564424
D017316	Fadrozole	Fadrozole results in increased expression of FSHR mRNA	19440503
D005473	Fluoxetine	Dinoprostone inhibits the reaction [Fluoxetine results in increased expression of FSHR mRNA]	20864192
D005473	Fluoxetine	Fluoxetine results in increased expression of FSHR mRNA	20864192
D005473	Fluoxetine	Fluoxetine results in decreased expression of FSHR mRNA	19493577
D005485	Flutamide	Flutamide affects the expression of FSHR mRNA	25564424
D006064	Gonadotropins, Equine	"bisphenol A promotes the reaction [[Gonadotropins, Equine co-treated with Chorionic Gonadotropin] results in increased expression of FSHR mRNA]"	28648634
D006064	Gonadotropins, Equine	"[Gonadotropins, Equine co-treated with Chorionic Gonadotropin] results in increased expression of FSHR mRNA"	28648634
D006064	Gonadotropins, Equine	"Gonadotropins, Equine results in increased expression of FSHR mRNA"	15831568
D006064	Gonadotropins, Equine	"bisphenol A promotes the reaction [Gonadotropins, Equine results in increased expression of FSHR mRNA]"	28648634
D006064	Gonadotropins, Equine	"Gonadotropins, Equine results in increased expression of FSHR mRNA"	28648634
D006063	Chorionic Gonadotropin	"bisphenol A promotes the reaction [[Gonadotropins, Equine co-treated with Chorionic Gonadotropin] results in increased expression of FSHR mRNA]"	28648634
D006063	Chorionic Gonadotropin	"[Gonadotropins, Equine co-treated with Chorionic Gonadotropin] results in increased expression of FSHR mRNA"	28648634
D007654	Ketoconazole	Ketoconazole results in increased expression of FSHR mRNA	22417765
C008261	lead acetate	lead acetate results in decreased expression of FSHR mRNA	29273543
D016729	Leuprolide	[Leuprolide co-treated with Testosterone] results in decreased expression of FSHR mRNA	16032706
C482199	lipopolysaccharide, E coli O55-B5	"lipopolysaccharide, E coli O55-B5 results in decreased expression of FSHR mRNA"	28870491
D008070	Lipopolysaccharides	Cryptoxanthins inhibits the reaction [Lipopolysaccharides results in decreased expression of FSHR mRNA]	26686910
D008070	Lipopolysaccharides	Lipopolysaccharides results in decreased expression of FSHR mRNA	26686910
D008731	Methoxychlor	Methoxychlor results in decreased expression of FSHR mRNA	22285353
C016599	mono-(2-ethylhexyl)phthalate	mono-(2-ethylhexyl)phthalate results in decreased expression of FSHR mRNA	22401849
C063509	N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide	N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [[Testosterone co-treated with FSHB protein] results in increased expression of FSHR mRNA]	16641147
C025256	nonylphenol	nonylphenol analog results in increased expression of FSHR protein	25242005
C025256	nonylphenol	nonylphenol results in decreased expression of FSHR protein	27832966
C025256	nonylphenol	nonylphenol results in increased expression of FSHR mRNA	27832966
C016340	o,p'-DDT	"o,p'-DDT promotes the reaction [[FSHB protein results in increased activity of FSHR protein] which results in increased abundance of Cyclic AMP]"	26895433
C510603	Org 41841	Org 41841 results in increased localization of FSHR protein	18848862
C510603	Org 41841	Org 41841 results in increased localization of FSHR protein mutant form	18848862
D010126	Ozone	Ozone inhibits the reaction [Water Pollutants results in increased expression of FSHR mRNA]	22856545
D017239	Paclitaxel	Paclitaxel results in decreased expression of FSHR mRNA	23956100
C101816	perfluoro-n-nonanoic acid	perfluoro-n-nonanoic acid results in decreased expression of FSHR mRNA	20580666
D015232	Dinoprostone	Dinoprostone inhibits the reaction [Fluoxetine results in increased expression of FSHR mRNA]	20864192
D010852	Picrotoxin	Picrotoxin results in increased expression of FSHR mRNA	15170462
D011192	Potassium Dichromate	Ascorbic Acid inhibits the reaction [Potassium Dichromate results in decreased expression of FSHR mRNA]	23470461
D011192	Potassium Dichromate	Ascorbic Acid inhibits the reaction [Potassium Dichromate results in decreased expression of FSHR protein]	23470461
D011192	Potassium Dichromate	Potassium Dichromate results in decreased expression of FSHR mRNA	23470461\|2819218
D011192	Potassium Dichromate	Potassium Dichromate results in decreased expression of FSHR protein	23470461\|2819218
C045362	prochloraz	prochloraz results in increased expression of FSHR mRNA	21158436
C045362	prochloraz	prochloraz results in decreased expression of FSHR mRNA	21470553
C045950	propiconazole	propiconazole results in increased expression of FSHR mRNA	23339182
C017947	sodium arsenite	sodium arsenite affects the methylation of FSHR gene	28589171
D012969	Sodium Fluoride	Sodium Fluoride results in decreased expression of FSHR protein	24071475
D014284	Triiodothyronine	Triiodothyronine results in increased expression of FSHR mRNA	17403546
D013739	Testosterone	bicalutamide inhibits the reaction [Testosterone results in increased expression of FSHR mRNA]	16641147
D013739	Testosterone	N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [[Testosterone co-treated with FSHB protein] results in increased expression of FSHR mRNA]	16641147
D013739	Testosterone	[Testosterone co-treated with FSHB protein] results in increased expression of FSHR mRNA	16641147
D013739	Testosterone	Testosterone results in increased expression of FSHR mRNA	16641147
D013739	Testosterone	Disulfiram inhibits the reaction [[FSHB protein co-treated with LHB protein co-treated with Testosterone] results in increased expression of FSHR mRNA]	22285649
D013739	Testosterone	[FSHB protein co-treated with LHB protein co-treated with Testosterone] results in increased expression of FSHR mRNA	22285649
D013739	Testosterone	[Leuprolide co-treated with Testosterone] results in decreased expression of FSHR mRNA	16032706
D043343	Testosterone Propionate	Testosterone Propionate results in increased expression of FSHR mRNA	20858754
D013749	Tetrachlorodibenzodioxin	alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of FSHR protein]	20823264
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin results in decreased expression of FSHR protein	20823264
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin inhibits the reaction [FSHB protein results in increased expression of FSHR mRNA]	10746652
C009954	trilostane	trilostane affects the expression of FSHR mRNA	25564424
C005445	triphenyl phosphate	triphenyl phosphate results in increased expression of FSHR mRNA	23603146\|2686534
C016805	tris(1,3-dichloro-2-propyl)phosphate	"tris(1,3-dichloro-2-propyl)phosphate results in increased expression of FSHR mRNA"	23603146\|2563791
C013320	tris(2-butoxyethyl) phosphate	tris(2-butoxyethyl) phosphate results in increased expression of FSHR mRNA	27131816
D001335	Vehicle Emissions	Vehicle Emissions affects the methylation of FSHR gene	25560391
D001335	Vehicle Emissions	Vehicle Emissions results in increased expression of FSHR mRNA	17365030
D001335	Vehicle Emissions	Vehicle Emissions results in increased expression of FSHR mRNA	19100318
C025643	vinclozolin	vinclozolin results in increased expression of FSHR mRNA	21126777
D014873	Water Pollutants	Ozone inhibits the reaction [Water Pollutants results in increased expression of FSHR mRNA]	22856545
D014873	Water Pollutants	Water Pollutants results in decreased expression of FSHR mRNA	22856545
D014873	Water Pollutants	Water Pollutants results in increased expression of FSHR mRNA	22856545

GO/Pathway

GO ID	GO Term	Qualifier	Evidence	PubMed
GO:0004963	follicle-stimulating hormone receptor activity	-	IBA	21873635
GO:0004963	follicle-stimulating hormone receptor activity	-	IDA	24692546
GO:0004963	follicle-stimulating hormone receptor activity	-	IMP	11847099
GO:0005515	protein binding	-	IPI	15196694 17030088 20600589
GO:0008528	G-protein coupled peptide receptor activity	-	IBA	21873635

GO ID	GO Term	Qualifier	Evidence	PubMed
GO:0007186	G-protein coupled receptor signaling pathway	-	IDA	24692546
GO:0007186	G-protein coupled receptor signaling pathway	-	TAS	-
GO:0007189	adenylate cyclase-activating G-protein coupled receptor signaling pathway	-	IBA	21873635
GO:0007190	activation of adenylate cyclase activity	-	IBA	21873635
GO:0007283	spermatogenesis	-	TAS	9020851
GO:0007292	female gamete generation	-	TAS	9020851
GO:0008406	gonad development	-	TAS	9020851
GO:0008584	male gonad development	-	IEP	17848411
GO:0008585	female gonad development	-	TAS	7553856
GO:0009755	hormone-mediated signaling pathway	-	IBA	21873635
GO:0010738	regulation of protein kinase A signaling	-	IMP	24058690
GO:0014068	positive regulation of phosphatidylinositol 3-kinase signaling	-	IMP	24058690
GO:0042699	follicle-stimulating hormone signaling pathway	-	IDA	24692546
GO:0042699	follicle-stimulating hormone signaling pathway	-	IMP	11847099
GO:0045762	positive regulation of adenylate cyclase activity	-	IMP	11847099
GO:0070374	positive regulation of ERK1 and ERK2 cascade	-	IDA	24058690
GO:0071372	cellular response to follicle-stimulating hormone stimulus	-	IMP	11847099

GO ID	GO Term	Qualifier	Evidence	PubMed
GO:0005622	intracellular	-	IEA	-
GO:0005886	plasma membrane	-	IDA	11847099
GO:0005886	plasma membrane	-	TAS	-
GO:0005887	integral component of plasma membrane	-	IBA	21873635
GO:0016021	integral component of membrane	-	IDA	24692546
GO:0043235	receptor complex	-	IDA	24692546

KEGG ID	KEGG Term
hsa04080	Neuroactive ligand-receptor interaction

Reactome ID	Reactome Term	Evidence
R-HSA-162582	Signal Transduction	TAS
R-HSA-372790	Signaling by GPCR	TAS
R-HSA-373076	Class A/1 (Rhodopsin-like receptors)	TAS
R-HSA-375281	Hormone ligand-binding receptors	TAS
R-HSA-388396	GPCR downstream signalling	TAS
R-HSA-418555	G alpha (s) signalling events	TAS
R-HSA-500792	GPCR ligand binding	TAS

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID	Title (Year)	Author	Journal
29617818	FSHB -211 G>T is a major genetic modulator of reproductive physiology and health in childbearing age women. (2018 May 1)	Rull K	Hum Reprod
17288166	[The expression of gene encoding folitropin receptor in granulosa cells in women smoking cigarettes and nonsmokers participating in vitro fertilization programme]. (2006)	Josiak M	Przegl Lek
24847019	In utero exposure to cigarette smoke dysregulates human fetal ovarian developmental signalling. (2014 Jul)	Fowler PA	Hum Reprod