Gene: HEPACAM2

253012
MIKI
HEPACAM family member 2
protein-coding
7q21.2
Ensembl:ENSG00000188175 MIM:614133 Vega:OTTHUMG00000131732 UniprotKB:A8MVW5
NG_051957.1
PubMed
0   ANCO-SNPs
ND
1   
NA (AD)  NA (ND)   (Frontal_Cortex)
7.845e-1 (AD)  5.097e-2 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
APOC10.351
ECEL10.338
IRX30.334
TSGA10IP0.329
FEZF10.327
SLITRK60.321
IRX10.312
ANAPC100.312
HOXD80.31
IRX20.308

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
LCE5A-0.245
STAB2-0.224
SLC6A13-0.22
NUTM2F-0.216
RNF148-0.208
HNRNPCL1-0.207
TM4SF5-0.202
DQX1-0.201
DEFB1-0.199
TMEM244-0.198

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
D016604Aflatoxin B1Aflatoxin B1 results in decreased methylation of HEPACAM2 gene27153756
D018501Antirheumatic AgentsAntirheumatic Agents results in increased expression of HEPACAM2 mRNA24449571
C547126AZM551248AZM551248 results in decreased expression of HEPACAM2 mRNA22323515
C006780bisphenol Abisphenol A results in decreased expression of HEPACAM2 mRNA25181051
C006780bisphenol Abisphenol A results in increased methylation of HEPACAM2 gene28505145
D002509CephaloridineCephaloridine results in increased expression of HEPACAM2 mRNA18500788
D003300CopperCopper deficiency results in increased expression of HEPACAM2 mRNA26033743
D003907DexamethasoneDexamethasone inhibits the reaction [RX3 gene mutant form affects the expression of HEPACAM2 mRNA]27941970
D004397FonofosFonofos results in decreased methylation of HEPACAM2 promoter22847954
C039281furanfuran results in increased expression of HEPACAM2 mRNA27387713
C008261lead acetatelead acetate results in increased expression of HEPACAM2 mRNA22609695
D037742Nanotubes, Carbon"Nanotubes, Carbon analog results in decreased expression of HEPACAM2 mRNA"25554681
D037742Nanotubes, Carbon"Nanotubes, Carbon results in decreased expression of HEPACAM2 mRNA"25554681
D010278ParathionParathion results in decreased methylation of HEPACAM2 promoter22847954
D053260SootSoot results in decreased expression of HEPACAM2 mRNA22461453
C012568terbufosterbufos results in decreased methylation of HEPACAM2 promoter22847954
C009495titanium dioxidetitanium dioxide results in increased expression of HEPACAM2 mRNA28181387
C015559trimellitic anhydridetrimellitic anhydride results in decreased expression of HEPACAM2 mRNA19042947
D014635Valproic AcidValproic Acid results in decreased methylation of HEPACAM2 gene29154799
D001335Vehicle EmissionsVehicle Emissions results in decreased methylation of HEPACAM2 gene25560391
C029297vinylidene chloridevinylidene chloride results in decreased expression of HEPACAM2 mRNA26682919

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0005515protein binding-IPI22864114  
GO ID GO Term Qualifier Evidence PubMed
GO:0007098centrosome cycle-IBA21873635  
GO:0007098centrosome cycle-IMP22864114  
GO:0051301cell division-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO:0000139Golgi membrane-IEA-  
GO:0005794Golgi apparatus-IBA21873635  
GO:0005794Golgi apparatus-IDA22864114  
GO:0005813centrosome-IBA21873635  
GO:0005813centrosome-IDA22864114  
GO:0005819spindle-IBA21873635  
GO:0005819spindle-IDA22864114  
GO:0016021integral component of membrane-IEA-  
GO:0030496midbody-IBA21873635  
GO:0030496midbody-IDA22864114  
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
25110502Effects of smoking cessation on gene expression in human leukocytes of chronic smoker. (2014 Jul)Kim SJPsychiatry Investig