Gene: TMEM244

253582
C6orf191|bA174C7.4
transmembrane protein 244
protein-coding
6q22.33
Ensembl:ENSG00000203756 Vega:OTTHUMG00000015553 UniprotKB:Q5VVB8
NC_000006.12
SNP Mapped
2   ANCO-SNPs
AD
0   
NA (AD)  NA (ND)   (Frontal_Cortex)
3.744e-1 (AD)  3.752e-1 (ND)

ANCO-SNPs

SNP ID Position Alleles Trait Variation Type
rs6912805chr6:129834568 (GRCh38.p7)T>Calcohol dependenceSNV(Single Nucleotide Variation)
rs9492393chr6:129833522 (GRCh38.p7)T>Calcohol dependenceSNV(Single Nucleotide Variation)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
ARHGEF280.616
RSPO30.582
SEMA3A0.572
SLIT30.568
PDE1A0.567
MFSD60.561
ISLR0.556
MCTP10.553
THEMIS0.552
PRUNE20.551

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
C4orf19-0.354
MTRNR2L8-0.354
HGF-0.325
SYPL2-0.324
PLA2G5-0.322
TFAP2C-0.321
TCF7L1-0.307
FGF11-0.304
TSPAN12-0.3
IMPA2-0.3

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
D000393Air PollutantsAir Pollutants analog results in increased expression of TMEM244 mRNA21757418
D000535Aluminum[APP protein modified form binds to Aluminum] which results in decreased expression of TMEM244 mRNA21298039
C519728archazolid Barchazolid B results in decreased expression of TMEM244 mRNA25218289
C016366dibenzothiophenedibenzothiophene results in decreased expression of TMEM244 mRNA23656968
C561695(+)-JQ1 compound(+)-JQ1 compound results in decreased expression of TMEM244 mRNA24796395
D014635Valproic AcidValproic Acid results in decreased methylation of TMEM244 gene29154799

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO ID GO Term Qualifier Evidence PubMed
GO ID GO Term Qualifier Evidence PubMed
GO:0016021integral component of membrane-IEA-  
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence

Interactions (STRING v10.5, Interaction Score >= 0.400)

There is no Interaction data for this gene.

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal