Gene: G6PD

2539
G6PD1
glucose-6-phosphate dehydrogenase
protein-coding
Xq28
Ensembl:ENSG00000160211 MIM:305900 Vega:OTTHUMG00000024237 UniprotKB:P11413
NG_009015.2
PubMed
ND|AD
7   
NA (AD)  NA (ND)   (Frontal_Cortex)
NA (AD)  NA (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
AP1B10.934
OGDH0.918
AP3D10.912
GRINA0.909
CSNK1D0.906
YIPF30.904
CARM10.903
WBP20.903
PACS10.901
CAPN10.901

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
OR4F5-0.735
OR4F29-0.69
OR6C74-0.305
KCNJ15-0.3
CTNNA3-0.295
CPA3-0.291
MTRNR2L6-0.291
CNTF-0.289
OR52B4-0.289
DNASE1L3-0.288

Drugs/Compounds

ID Drug Name Drug Type CAS Num Status Role
DB03085Glycolic acidSmall Molecule79-14-1Approved|InvestigationalTarget
DB034612'-Monophosphoadenosine 5'-DiphosphoriboseSmall MoleculeExperimentalTarget
DB0510716-BromoepiandrosteroneSmall Molecule28507-02-0InvestigationalTarget
DB11638ArtenimolSmall Molecule71939-50-9Approved|InvestigationalTarget
ID Drug Name Action PubMed
C0264861,2,5,6-dibenzanthracene"[Benzo(a)pyrene co-treated with 1,2,5,6-dibenzanthracene] affects the expression of G6PD mRNA"17690111
C0415071-methylphenanthrene[Benzo(a)pyrene co-treated with 1-methylphenanthrene] affects the expression of G6PD mRNA17690111
C0939732-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Cadmium Chloride results in increased expression of G6PD mRNA]12717738
C0467282,2'-azobis(2-amidinopropane)"2,2'-azobis(2-amidinopropane) results in decreased activity of G6PD protein"12628296
C1111182',3,3',4',5-pentachloro-4-hydroxybiphenyl"2',3,3',4',5-pentachloro-4-hydroxybiphenyl results in decreased expression of G6PD mRNA"19114083
C0109252,5-dihydroxybenzoic acid"2,5-dihydroxybenzoic acid results in decreased activity of G6PD protein mutant form"5432368
C0109252,5-dihydroxybenzoic acid"2,5-dihydroxybenzoic acid inhibits the reaction [Benzoyl Peroxide results in decreased activity of G6PD protein]"15454305
C5724913-(2-hydroxy-4-(2-methylnonan-2-yl)phenyl)cyclohexan-1-ol3-(2-hydroxy-4-(2-methylnonan-2-yl)phenyl)cyclohexan-1-ol results in increased expression of G6PD protein26194647
C0006230213-(pyridin-3-ylsulfonyl)-5-(trifluoromethyl)-2H-chromen-2-one3-(pyridin-3-ylsulfonyl)-5-(trifluoromethyl)-2H-chromen-2-one results in increased expression of G6PD mRNA28790194
C0006230213-(pyridin-3-ylsulfonyl)-5-(trifluoromethyl)-2H-chromen-2-oneNFE2L2 protein affects the reaction [3-(pyridin-3-ylsulfonyl)-5-(trifluoromethyl)-2H-chromen-2-one results in increased expression of G6PD mRNA]28790194
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of G6PD mRNA"27188386
C0326424-aminophenylarsenoxide4-aminophenylarsenoxide binds to G6PD protein26598702
C0326424-aminophenylarsenoxidearsenic trioxide inhibits the reaction [4-aminophenylarsenoxide binds to G6PD protein]26598702
C0069834-chlorobiphenyl4-chlorobiphenyl metabolite results in increased expression of G6PD mRNA25417049
C0118674-hydroxyphenylethanol4-hydroxyphenylethanol inhibits the reaction [Streptozocin results in decreased activity of G6PD protein]25641191
C0022024-oxoretinoic acid4-oxoretinoic acid results in increased expression of G6PD mRNA15982314
C0293704-toluidine4-toluidine results in increased expression of G6PD mRNA27638505
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of G6PD mRNA"27188386
C0106436-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid"6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [Cadmium Chloride results in increased expression of G6PD mRNA]"12717738
D000079AcetaldehydeAcetaldehyde results in increased activity of G6PD protein8123704
D000079AcetaldehydeAcetaldehyde results in increased expression of G6PD mRNA8123704
D000082AcetaminophenAcetaminophen affects the expression of G6PD mRNA25064622
D000082AcetaminophenAcetaminophen results in increased expression of G6PD mRNA22230336|2539940
D000082AcetaminophenAcetaminophen results in increased expression of G6PD protein22230336
D000111AcetylcysteineAcetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of G6PD mRNA]12717738
D000111AcetylcysteineAcetylcysteine inhibits the reaction [Oxygen deficiency results in increased expression of G6PD mRNA]15225644
D000111AcetylcysteineAcetylcysteine results in increased activity of G6PD protein3099627
D016604Aflatoxin B1Aflatoxin B1 results in increased methylation of G6PD gene27153756
D000420AlbuterolAlbuterol results in increased activity of G6PD protein1978808
C103303alitretinoinalitretinoin results in increased expression of G6PD mRNA15982314
C038491allyl sulfideallyl sulfide inhibits the reaction [Cadmium Chloride results in decreased activity of G6PD protein]18972399
D000535AluminumAluminum results in increased activity of G6PD protein16979867
D000535AluminumAluminum results in increased activity of G6PD protein16572710
D017607Aluminum CompoundsAluminum Compounds results in decreased activity of G6PD protein28665548
C001864aluminum phosphidealuminum phosphide results in decreased activity of G6PD protein20929055
D000638AmiodaroneAmiodarone affects the expression of G6PD mRNA25064622
D000638AmiodaroneAmiodarone results in increased expression of G6PD mRNA19774075
D000643Ammonium ChlorideAmmonium Chloride affects the expression of G6PD mRNA16483693
D000738AndrosteroneAndrosterone results in decreased activity of G6PD protein7752092
D000966Antimony Potassium TartrateAntimony Potassium Tartrate results in increased expression of G6PD mRNA28713220
D000966Antimony Potassium TartrateAntimony Potassium Tartrate results in increased expression of G6PD protein28713220
C061640arjunolic acidarjunolic acid inhibits the reaction [Streptozocin results in decreased activity of G6PD protein]19133311|1968244
D001151ArsenicArsenic results in decreased activity of G6PD protein21864513|2222986
D001151Arsenicsilybin inhibits the reaction [Arsenic results in decreased activity of G6PD protein]22229868
C025657arsenic acidarsenic acid results in increased expression of G6PD protein19632019
C042120arsenic pentoxidearsenic pentoxide results in decreased activity of G6PD protein23363574
C006632arsenic trioxidearsenic trioxide inhibits the reaction [4-aminophenylarsenoxide binds to G6PD protein]26598702
C006632arsenic trioxidearsenic trioxide results in decreased expression of G6PD protein25419056
C006632arsenic trioxideG6PD protein results in decreased susceptibility to arsenic trioxide20707922
D017639Asbestos, Amosite"Asbestos, Amosite results in decreased activity of G6PD protein"14613721|1837041
D017639Asbestos, Amosite"Glutathione inhibits the reaction [Asbestos, Amosite results in decreased activity of G6PD protein]"14613721
D017638Asbestos, Crocidolite"Asbestos, Crocidolite binds to and results in decreased activity of G6PD protein"11978496
D017638Asbestos, Crocidolite"Asbestos, Crocidolite results in decreased activity of G6PD protein"18370412
C011669ascorbate-2-phosphateascorbate-2-phosphate results in increased activity of G6PD protein19746226
C011669ascorbate-2-phosphateascorbate-2-phosphate results in increased expression of G6PD mRNA19746226
C011669ascorbate-2-phosphateDehydroepiandrosterone inhibits the reaction [ascorbate-2-phosphate results in increased activity of G6PD protein]19746226
D001241AspirinAspirin results in decreased activity of G6PD protein mutant form5432368
D001241AspirinG6PD results in decreased susceptibility to Aspirin5432368
C005948astaxanthineastaxanthine results in increased activity of G6PD protein28665548
D001262AtenololAtenolol inhibits the reaction [Dopamine results in increased activity of G6PD protein]1978808
D001262AtenololAtenolol inhibits the reaction [Isoproterenol results in increased activity of G6PD protein]1978808
D001280AtrazineAtrazine results in increased expression of G6PD mRNA22982499
C051597Bandrowski's baseBandrowski's base results in increased expression of G6PD mRNA20566472
C006703benzo(b)fluoranthene[Benzo(a)pyrene co-treated with benzo(b)fluoranthene] affects the expression of G6PD mRNA17690111
D019324beta-Naphthoflavone[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of G6PD protein28903497
D019817Benzoic AcidBenzoic Acid results in increased expression of G6PD mRNA20566472
D001564Benzo(a)pyrene"[Benzo(a)pyrene co-treated with 1,2,5,6-dibenzanthracene] affects the expression of G6PD mRNA"17690111
D001564Benzo(a)pyrene[Benzo(a)pyrene co-treated with 1-methylphenanthrene] affects the expression of G6PD mRNA17690111
D001564Benzo(a)pyrene[Benzo(a)pyrene co-treated with benzo(b)fluoranthene] affects the expression of G6PD mRNA17690111
D001564Benzo(a)pyrene"[Benzo(a)pyrene co-treated with dibenzo(a,l)pyrene] affects the expression of G6PD mRNA"17690111
D001564Benzo(a)pyrene[Benzo(a)pyrene co-treated with fluoranthene] affects the expression of G6PD mRNA17690111
D001564Benzo(a)pyrene[Soot co-treated with Benzo(a)pyrene] results in increased expression of G6PD protein24464499
D001564Benzo(a)pyreneBenzo(a)pyrene results in decreased activity of G6PD protein11856576
D001585Benzoyl Peroxide"2,5-dihydroxybenzoic acid inhibits the reaction [Benzoyl Peroxide results in decreased activity of G6PD protein]"15454305
D001585Benzoyl PeroxideBenzoyl Peroxide results in decreased activity of G6PD protein12804013|1522590
D001585Benzoyl Peroxidecycloartenol inhibits the reaction [Benzoyl Peroxide results in decreased activity of G6PD protein]12804013
D001585Benzoyl PeroxideIsotretinoin inhibits the reaction [Benzoyl Peroxide results in decreased activity of G6PD protein]15225900
D001585Benzoyl PeroxidePlant Extracts inhibits the reaction [Benzoyl Peroxide results in decreased activity of G6PD protein]15629248
D004958EstradiolEstradiol results in decreased activity of G6PD protein11856576
C023888beta-hexachlorocyclohexanebeta-hexachlorocyclohexane results in increased activity of G6PD protein2461408
D001629BezafibrateBezafibrate inhibits the reaction [etomoxir results in increased activity of G6PD protein]3421940
C551172bis-N,N-dimethylamino-2-(N-methylpyrrolyl)methyl cyclopentadienyl titanium (IV)"bis-N,N-dimethylamino-2-(N-methylpyrrolyl)methyl cyclopentadienyl titanium (IV) results in decreased expression of G6PD mRNA"20162321
C006780bisphenol Abisphenol A results in increased expression of G6PD mRNA28159858
C006780bisphenol Abisphenol A results in increased expression of G6PD mRNA27474941
C006780bisphenol Abisphenol A results in increased expression of G6PD protein27474941
C006780bisphenol Abisphenol A results in increased expression of G6PD mRNA29275510
C006780bisphenol Abisphenol A affects the expression of G6PD mRNA25181051
C006780bisphenol Abisphenol A results in decreased expression of G6PD protein22649256
D000069286BortezomibBortezomib results in decreased expression of G6PD mRNA20977926
D002065BuspironeBuspirone results in decreased expression of G6PD mRNA24136188
D019328Buthionine SulfoximineButhionine Sulfoximine results in increased expression of G6PD mRNA12717738
D020122tert-Butylhydroperoxidetert-Butylhydroperoxide results in decreased activity of G6PD protein12628296
D020122tert-Butylhydroperoxidetert-Butylhydroperoxide results in increased activity of G6PD protein15336504
D020122tert-Butylhydroperoxidetert-Butylhydroperoxide results in increased activity of G6PD protein15336504
D020122tert-Butylhydroperoxidetert-Butylhydroperoxide results in increased activity of G6PD protein16928893
D002104CadmiumCadmium results in decreased activity of G6PD protein16752219
D002104CadmiumCadmium results in increased activity of G6PD protein16752219
D002104CadmiumCadmium results in increased expression of G6PD mRNA18394669
D002104Cadmium[Cadmium co-treated with Zinc] results in increased activity of G6PD protein20143450
D002104CadmiumCadmium results in increased activity of G6PD protein20143450
D002104CadmiumCadmium results in decreased activity of G6PD protein17698948
D002104CadmiumCadmium results in decreased expression of G6PD17125799
D002104CadmiumCadmium results in decreased expression of G6PD protein19615871
D002104Cadmiumdiallyl tetrasulfide inhibits the reaction [Cadmium results in decreased activity of G6PD protein]17698948
D002104Cadmiumdiallyl tetrasulfide inhibits the reaction [Cadmium results in decreased expression of G6PD]17125799
D002104Cadmiummyricetin inhibits the reaction [[Streptozocin co-treated with Cadmium] results in decreased activity of G6PD protein]24923654
D002104CadmiumQuercetin inhibits the reaction [Cadmium results in decreased expression of G6PD protein]19615871
D002104Cadmium[Streptozocin co-treated with Cadmium] results in decreased activity of G6PD protein24923654
D002104CadmiumCadmium results in increased expression of G6PD mRNA24095957
D019256Cadmium ChlorideCadmium Chloride affects the expression of G6PD protein24874008
D019256Cadmium ChlorideCadmium Chloride results in increased expression of G6PD mRNA26525392
D019256Cadmium ChlorideCadmium Chloride results in decreased activity of G6PD protein18414974|1856190
D019256Cadmium ChlorideTaurine inhibits the reaction [Cadmium Chloride results in decreased activity of G6PD protein]18414974|1856190
D019256Cadmium Chloride2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Cadmium Chloride results in increased expression of G6PD mRNA]12717738
D019256Cadmium Chloride"6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [Cadmium Chloride results in increased expression of G6PD mRNA]"12717738
D019256Cadmium ChlorideAcetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of G6PD mRNA]12717738
D019256Cadmium Chlorideallyl sulfide inhibits the reaction [Cadmium Chloride results in decreased activity of G6PD protein]18972399
D019256Cadmium ChlorideCadmium Chloride results in decreased activity of G6PD protein15454312|1897239
D019256Cadmium ChlorideCadmium Chloride results in decreased expression of G6PD protein19063931
D019256Cadmium ChlorideCadmium Chloride results in increased activity of G6PD protein12717738
D019256Cadmium ChlorideCadmium Chloride results in increased expression of G6PD mRNA12717738|1525286
D019256Cadmium Chloridehesperetin inhibits the reaction [Cadmium Chloride results in decreased activity of G6PD protein]21134734
D019256Cadmium Chloridenaringenin inhibits the reaction [Cadmium Chloride results in decreased expression of G6PD protein]19063931
D019256Cadmium ChloridePlant Extracts inhibits the reaction [Cadmium Chloride results in decreased activity of G6PD protein]23961183
D019256Cadmium ChlorideS-ethyl glutathione inhibits the reaction [Cadmium Chloride results in increased expression of G6PD mRNA]12717738
D019256Cadmium Chloridezinc chloride inhibits the reaction [Cadmium Chloride results in decreased activity of G6PD protein]18972399
C035196cadmium nitratecadmium nitrate results in decreased activity of G6PD protein28557068
C040048caffeic acidcaffeic acid results in decreased activity of G6PD protein25130191
D002119Calcium CarbonateCalcium Carbonate results in decreased activity of G6PD protein16735067
C058819calphostin Ccalphostin C results in decreased activity of G6PD protein19429815
D012721CarbarylCarbaryl results in increased activity of G6PD protein27214522
D012721Carbaryl[Malathion co-treated with Carbaryl] results in increased activity of G6PD protein27214522
D012721CarbarylPlant Extracts inhibits the reaction [[Malathion co-treated with Carbaryl] results in increased activity of G6PD protein]27214522
D002244CarbonCarbon inhibits the reaction [lead nitrate results in increased expression of G6PD mRNA]18346799
D002509CephaloridineCephaloridine results in increased expression of G6PD mRNA18500788
C016299chelerythrinechelerythrine results in decreased activity of G6PD protein19429815
C001599chloritechlorite results in decreased activity of G6PD protein27478981
D020111Chlorodiphenyl (54% Chlorine)Chlorodiphenyl (54% Chlorine) results in increased activity of G6PD protein3099627|4005852
D002746ChlorpromazineChlorpromazine affects the expression of G6PD mRNA25064622
D002746ChlorpromazineChlorpromazine analog results in decreased expression of G6PD mRNA15924885
D002791Cholesterol, Dietary"Cholesterol, Dietary results in increased expression of G6PD mRNA"19509184
D002791Cholesterol, Dietary"[Fructose co-treated with Dietary Fats co-treated with Cholesterol, Dietary] results in increased expression of G6PD mRNA"19509184
D002791Cholesterol, Dietary"[CCL7 protein results in increased susceptibility to [Dietary Fats co-treated with Cholesterol, Dietary]] which results in increased activity of G6PD protein"23462015
C023600chromic oxidechromic oxide affects the expression of G6PD mRNA15003702
C074702chromium hexavalent ionchromium hexavalent ion results in decreased activity of G6PD protein15980013
C074702chromium hexavalent ionchromium hexavalent ion affects the expression of G6PD mRNA15003702
C012843cinnamic aldehydecinnamic aldehyde results in increased expression of G6PD mRNA19524605
C020722cinnamyl alcoholcinnamyl alcohol results in increased expression of G6PD mRNA20566472
D002939CiprofloxacinG6PD protein mutant form results in increased susceptibility to Ciprofloxacin20127091
C007078citronellolcitronellol inhibits the reaction [Streptozocin results in decreased activity of G6PD protein]26944432
C018021cobaltous chloridecobaltous chloride results in decreased expression of G6PD mRNA19376846
C018021cobaltous chloridecobaltous chloride results in increased activity of G6PD protein15225644
C018021cobaltous chloridecobaltous chloride results in increased expression of G6PD mRNA15225644
C025913cobaltous nitratecobaltous nitrate results in decreased activity of G6PD protein23363574
D003042CocaineCocaine results in increased expression of G6PD protein25100957
D009243NAD[G6PD protein co-treated with Glucose-6-Phosphate] results in increased chemical synthesis of NAD23295224
D009249NADPG6PD protein results in increased reduction of NADP5432368
D009249NADPNADP results in increased expression of G6PD protein1922005
D003300Copper[NSC 689534 binds to Copper] which results in decreased expression of G6PD mRNA20971185
D003300CopperCopper affects the expression of G6PD mRNA23825565
D003300CopperCopper results in increased expression of G6PD mRNA18394669
D019327Copper SulfateCopper Sulfate results in decreased expression of G6PD mRNA23660017
D019327Copper SulfateCopper Sulfate results in decreased expression of G6PD protein23660017
C007164cumene hydroperoxidecumene hydroperoxide results in increased activity of G6PD protein16928893
D003474CurcuminCurcumin results in increased expression of G6PD mRNA18299980
C100089cycloartenolcycloartenol inhibits the reaction [Benzoyl Peroxide results in decreased activity of G6PD protein]12804013
D003513CycloheximideCycloheximide inhibits the reaction [Isoproterenol results in increased activity of G6PD protein]1978808
D016572CyclosporineCyclosporine affects the expression of G6PD mRNA25064622
D016572CyclosporineCyclosporine results in decreased expression of G6PD mRNA27989131
D016572CyclosporineCyclosporine results in increased expression of G6PD mRNA25562108
C017160cypermethrin[cypermethrin co-treated with propetamphos] results in decreased activity of G6PD protein25926273
C017160cypermethrincypermethrin results in decreased activity of G6PD protein25926273
D003609DactinomycinDactinomycin promotes the reaction [Endosulfan results in decreased activity of G6PD protein]15202864
D003609DactinomycinDactinomycin inhibits the reaction [Isoproterenol results in increased activity of G6PD protein]1978808
D003622DapsoneG6PD protein mutant form results in increased susceptibility to Dapsone7752092
D003634DDT[DDT co-treated with Methylmercury Compounds] results in increased activity of G6PD protein18675336
D003634DDTDDT results in increased activity of G6PD protein12667599
D003634DDTInositol inhibits the reaction [DDT results in increased activity of G6PD protein]12667599
D003687DehydroepiandrosteroneDehydroepiandrosterone inhibits the reaction [ascorbate-2-phosphate results in increased activity of G6PD protein]19746226
D003907DexamethasoneDexamethasone inhibits the reaction [RX3 gene mutant form affects the expression of G6PD mRNA]27941970
D003907DexamethasoneDexamethasone results in decreased activity of G6PD protein15895680
C431585diallyl tetrasulfidediallyl tetrasulfide inhibits the reaction [Cadmium results in decreased activity of G6PD protein]17698948
C431585diallyl tetrasulfidediallyl tetrasulfide inhibits the reaction [Cadmium results in decreased expression of G6PD]17125799
D003976DiazinonDiazinon affects the expression of G6PD mRNA22546817
C041517dibenzo(a,l)pyrene"[Benzo(a)pyrene co-treated with dibenzo(a,l)pyrene] affects the expression of G6PD mRNA"17690111
D002945Cisplatin[Cisplatin co-treated with jinfukang] results in increased expression of G6PD mRNA27392435
D002945CisplatinCisplatin results in increased expression of G6PD mRNA21151649
D004026DieldrinDieldrin affects the expression of G6PD mRNA22546817
D004041Dietary Fats"[Fructose co-treated with Dietary Fats co-treated with Cholesterol, Dietary] results in increased expression of G6PD mRNA"19509184
D004041Dietary Fats"[CCL7 protein results in increased susceptibility to [Dietary Fats co-treated with Cholesterol, Dietary]] which results in increased activity of G6PD protein"23462015
D004041Dietary FatsDietary Fats analog results in decreased expression of G6PD mRNA12669817
C014476diethyl maleatediethyl maleate results in increased activity of G6PD protein3099627
D004052Diethylnitrosamine[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of G6PD protein28903497
D004052Diethylnitrosamine[Diethylnitrosamine co-treated with Methapyrilene] results in increased expression of G6PD protein28903497
D004052Diethylnitrosamine[Diethylnitrosamine co-treated with Phenobarbital] results in decreased activity of G6PD protein16188247
D004052Diethylnitrosamine[Diethylnitrosamine co-treated with Piperonyl Butoxide] results in increased expression of G6PD protein28903497
D004052Diethylnitrosamine[Diethylnitrosamine co-treated with Thioacetamide] results in increased expression of G6PD protein28903497
D004052DiethylnitrosaminePlant Extracts inhibits the reaction [[Diethylnitrosamine co-treated with Phenobarbital] results in decreased activity of G6PD protein]16188247
D004077DigoxinDigoxin results in decreased activity of G6PD protein26820767
C039060dihydroartemisinindihydroartemisinin analog binds to G6PD protein26340163
D002117CalcitriolCalcitriol results in increased activity of G6PD protein8910257
D002117CalcitriolCalcitriol results in increased expression of G6PD mRNA12040012|1600243
D002117Calcitriol[Testosterone co-treated with Calcitriol] results in increased expression of G6PD mRNA21592394
C015835dimethyl-4-toluidinedimethyl-4-toluidine results in increased expression of G6PD mRNA27638505
D004137DinitrochlorobenzeneDinitrochlorobenzene results in increased expression of G6PD mRNA20566472
D004178DiquatDiquat results in increased activity of G6PD protein28108222
D004178DiquatDiquat results in increased activity of G6PD protein8934631
D004178DiquatDiquat results in increased expression of G6PD mRNA8934631
D004178DiquatDiquat results in increased expression of G6PD protein8934631
D004221DisulfiramDisulfiram results in increased expression of G6PD mRNA20566472
D004237DiuronDiuron results in increased expression of G6PD mRNA21551480
D004280DobutamineDobutamine results in increased activity of G6PD protein1978808
D004298DopamineAtenolol inhibits the reaction [Dopamine results in increased activity of G6PD protein]1978808
D004298DopamineDopamine results in decreased activity of G6PD protein26820767
D004298DopamineDopamine results in increased activity of G6PD protein1978808
D004317DoxorubicinDoxorubicin results in increased expression of G6PD mRNA16404146
D004317DoxorubicinDoxorubicin affects the expression of G6PD protein15909818
D004610Ellagic AcidEllagic Acid results in decreased activity of G6PD protein25130191
D004726EndosulfanDactinomycin promotes the reaction [Endosulfan results in decreased activity of G6PD protein]15202864
D004726EndosulfanEndosulfan results in decreased activity of G6PD protein15202864
D004726EndosulfanEndosulfan results in decreased expression of G6PD mRNA15202864
D004726EndosulfanEndosulfan results in decreased expression of G6PD protein15202864
D004726EndosulfanEndosulfan results in increased activity of G6PD protein7900959|8588293
D004785Environmental PollutantsEnvironmental Pollutants affects the expression of G6PD protein16998633
D004791Enzyme Inhibitors[Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation of G6PD protein23301498
C062669epicatechin gallateepicatechin gallate results in increased activity of G6PD protein26187476
C011246essential 303 forte[essential 303 forte co-treated with Silymarin] affects the activity of G6PD protein25903262
C011246essential 303 forte[essential 303 forte co-treated with Silymarin co-treated with Melatonin analog] affects the activity of G6PD protein25903262
D004997Ethinyl EstradiolEthinyl Estradiol affects the expression of G6PD mRNA25064622
D004997Ethinyl EstradiolEthinyl Estradiol results in decreased expression of G6PD mRNA17288598
C054207etomoxirBezafibrate inhibits the reaction [etomoxir results in increased activity of G6PD protein]3421940
C054207etomoxiretomoxir results in increased activity of G6PD protein3421940
D005054EugenolEugenol results in increased expression of G6PD mRNA20566472
D005280FenoterolFenoterol results in increased activity of G6PD protein1978808
C017690fenvaleratefenvalerate results in decreased activity of G6PD protein15313449
C024555ferric chlorideferric chloride results in decreased activity of G6PD protein24599681
C024555ferric chlorideferric chloride results in decreased expression of G6PD mRNA24599681
C020326ferric nitrilotriacetateferric nitrilotriacetate results in decreased activity of G6PD protein9667754
C020748ferrous sulfateferrous sulfate results in decreased activity of G6PD protein16735067
C004999ferulic acidferulic acid results in decreased activity of G6PD protein25130191
C007738fluoranthene[Benzo(a)pyrene co-treated with fluoranthene] affects the expression of G6PD mRNA17690111
D005459FluoridesFluorides results in decreased activity of G6PD protein19945446
D005485FlutamideFlutamide results in decreased expression of G6PD mRNA24793618
D005485FlutamideFlutamide results in increased expression of G6PD mRNA19299419|2413618
D002955LeucovorinLeucovorin inhibits the reaction [Methotrexate results in decreased activity of G6PD protein]21213337
D005632Fructose"[Fructose co-treated with Dietary Fats co-treated with Cholesterol, Dietary] results in increased expression of G6PD mRNA"19509184
D005632FructoseFructose results in increased activity of G6PD protein18346472
C039281furanfuran results in increased expression of G6PD mRNA25539665|2619464
D005665FurosemideFurosemide results in decreased activity of G6PD protein26820767
D005711GallopamilGallopamil inhibits the reaction [Isoproterenol results in increased activity of G6PD protein]1978808
C040641genistingenistin analog results in increased expression of G6PD mRNA16719502
D005839GentamicinsGentamicins results in increased expression of G6PD protein22061828
D005897GlafenineGlafenine results in increased expression of G6PD mRNA24136188
D019298Glucose-6-Phosphate[G6PD protein co-treated with Glucose-6-Phosphate] results in increased chemical synthesis of NAD23295224
D005976GlutaralGlutaral results in decreased activity of G6PD protein19490936
D005978Glutathione"Glutathione inhibits the reaction [Asbestos, Amosite results in decreased activity of G6PD protein]"14613721
D005978GlutathioneGlutathione inhibits the reaction [Oxygen deficiency results in increased expression of G6PD mRNA]15225644
D005905GlyburideGlyburide inhibits the reaction [Streptozocin results in decreased activity of G6PD protein]25641191
C071834glycidamideglycidamide results in increased expression of G6PD mRNA17822822
C031150glyoxylic acidglyoxylic acid results in decreased activity of G6PD protein15144222
C010974glyphosateglyphosate results in decreased activity of G6PD protein24636977|2862740
C010974glyphosateglyphosate results in increased activity of G6PD protein23820267
D006540HerbicidesHerbicides results in decreased activity of G6PD protein24636977
C013015hesperetinhesperetin inhibits the reaction [Cadmium Chloride results in decreased activity of G6PD protein]21134734
D006569HesperidinHesperidin results in decreased activity of G6PD protein25130191
D006569HesperidinHesperidin affects the reaction [LEPR protein affects the activity of G6PD protein]16427799
C080043hexyl cinnamic aldehydehexyl cinnamic aldehyde results in increased expression of G6PD mRNA20566472
D017313FenretinideFenretinide results in increased expression of G6PD protein25246272
D006861Hydrogen PeroxideHydrogen Peroxide results in increased activity of G6PD protein15336504
D006861Hydrogen PeroxideHydrogen Peroxide results in increased activity of G6PD protein15336504
D006861Hydrogen PeroxideHydrogen Peroxide results in increased expression of G6PD mRNA15922008
D006861Hydrogen Peroxide[Zinc Sulfate co-treated with Hydrogen Peroxide] results in increased expression of G6PD mRNA15922008
D006861Hydrogen PeroxideHydrogen Peroxide results in decreased activity of G6PD protein11856576
D007213IndomethacinIndomethacin results in increased expression of G6PD mRNA18299717
D007294InositolInositol inhibits the reaction [DDT results in increased activity of G6PD protein]12667599
D007294Inositol[Phytic Acid co-treated with Inositol] inhibits the reaction [Streptozocin results in decreased activity of G6PD protein]28757134
D015759Ionomycin[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of G6PD mRNA25613284
D007501IronIron results in decreased activity of G6PD protein16735067
C036643isoeugenolisoeugenol results in increased expression of G6PD mRNA20566472
D007529IsoflavonesIsoflavones results in increased expression of G6PD mRNA17374662
D007545IsoproterenolAtenolol inhibits the reaction [Isoproterenol results in increased activity of G6PD protein]1978808
D007545IsoproterenolCycloheximide inhibits the reaction [Isoproterenol results in increased activity of G6PD protein]1978808
D007545IsoproterenolDactinomycin inhibits the reaction [Isoproterenol results in increased activity of G6PD protein]1978808
D007545IsoproterenolGallopamil inhibits the reaction [Isoproterenol results in increased activity of G6PD protein]1978808
D007545IsoproterenolIsoproterenol results in increased activity of G6PD protein1978808
D007548Isosorbide DinitrateG6PD protein results in decreased susceptibility to Isosorbide Dinitrate6401899
C544151jinfukang[Cisplatin co-treated with jinfukang] results in increased expression of G6PD mRNA27392435
C544151jinfukangjinfukang results in increased expression of G6PD mRNA27392435
C561695(+)-JQ1 compound(+)-JQ1 compound results in increased expression of G6PD mRNA24796395
C410337K 7174K 7174 results in increased expression of G6PD mRNA24086573
D007648Kerosene"[Kerosene co-treated with Asbestos, Serpentine] results in increased activity of G6PD protein"9177657
D007654KetoconazoleKetoconazole results in increased expression of G6PD mRNA25399406
D019344Lactic AcidLactic Acid results in increased expression of G6PD mRNA20566472
C008261lead acetatelead acetate results in decreased activity of G6PD protein25228019
C008261lead acetate[naringenin co-treated with lead acetate] results in decreased activity of G6PD protein25228019
C017461lead nitrateCarbon inhibits the reaction [lead nitrate results in increased expression of G6PD mRNA]18346799
C017461lead nitratelead nitrate results in increased expression of G6PD mRNA18346799
C017461lead nitratelead nitrate results in decreased activity of G6PD protein28557068
C533894LG 100815LG 100815 results in decreased expression of G6PD mRNA16951191
D001556LindaneLindane results in increased activity of G6PD protein11222031
D001556LindaneLindane affects the activity of G6PD protein7535533|8519523
D001556LindaneLindane results in increased activity of G6PD protein2461408
C482199lipopolysaccharide, E coli O55-B5"lipopolysaccharide, E coli O55-B5 results in increased expression of G6PD mRNA"24972896
D008070LipopolysaccharidesLipopolysaccharides results in decreased expression of G6PD mRNA25613284
D008294Malathion[Malathion co-treated with Carbaryl] results in increased activity of G6PD protein27214522
D008294MalathionMalathion results in increased activity of G6PD protein27214522
D008294MalathionPlant Extracts inhibits the reaction [[Malathion co-treated with Carbaryl] results in increased activity of G6PD protein]27214522
C520506manganese tetrakis-(N-ethyl-2 pyridyl) porphyrinmanganese tetrakis-(N-ethyl-2 pyridyl) porphyrin results in decreased expression of G6PD protein23682840
D008550Melatonin[essential 303 forte co-treated with Silymarin co-treated with Melatonin analog] affects the activity of G6PD protein25903262
D008550MelatoninMelatonin results in increased activity of G6PD protein16224550
D008627Mercuric ChlorideMercuric Chloride results in increased activity of G6PD protein11222031
D008627Mercuric ChlorideMercuric Chloride results in increased activity of G6PD protein15977196
D008628MercuryMercury results in decreased activity of G6PD protein16752219
D008628MercuryMercury results in increased activity of G6PD protein16752219
D008628MercuryMercury results in decreased activity of G6PD protein10798623
D008701Methapyrilene[Diethylnitrosamine co-treated with Methapyrilene] results in increased expression of G6PD protein28903497
D008701MethapyrileneMethapyrilene results in increased expression of G6PD mRNA28903497
D008727MethotrexateLeucovorin inhibits the reaction [Methotrexate results in decreased activity of G6PD protein]21213337
D008727MethotrexateMethotrexate results in decreased activity of G6PD protein21213337
D008751Methylene BlueMethylene Blue results in increased activity of G6PD protein1901343
C004925methylmercuric chloridemethylmercuric chloride results in increased expression of G6PD mRNA23103053
C004925methylmercuric chloridemethylmercuric chloride results in increased expression of G6PD mRNA28001369
D008767Methylmercury Compounds[DDT co-treated with Methylmercury Compounds] results in increased activity of G6PD protein18675336
D008767Methylmercury CompoundsMethylmercury Compounds results in increased activity of G6PD protein18675336
D008767Methylmercury CompoundsMethylmercury Compounds results in increased expression of G6PD mRNA16966085
D008767Methylmercury CompoundsMethylmercury Compounds results in decreased activity of G6PD protein24941299
D008741Methyl MethanesulfonateMethyl Methanesulfonate results in increased expression of G6PD mRNA26011545
D008773Methylphenazonium MethosulfateMethylphenazonium Methosulfate results in increased activity of G6PD protein1901343
C033069methyl salicylatemethyl salicylate results in increased expression of G6PD mRNA20566472
D008790MetoprololMetoprolol inhibits the reaction [Norepinephrine results in increased activity of G6PD protein]1378361
D015741MetriboloneMetribolone results in decreased expression of G6PD protein17152098
D008920MisonidazoleG6PD protein affects the susceptibility to Misonidazole3053537
D008999MonocrotophosMonocrotophos affects the activity of G6PD protein24248738
D008999Monocrotophos[Monocrotophos co-treated with quinalphos] affects the activity of G6PD protein24248738
D009151Mustard GasMustard Gas analog results in increased activity of G6PD protein15147793
C040015myricetinmyricetin inhibits the reaction [[Streptozocin co-treated with Cadmium] results in decreased activity of G6PD protein]24923654
C005273naringeninnaringenin results in decreased activity of G6PD protein25130191
C005273naringenin[naringenin co-treated with lead acetate] results in decreased activity of G6PD protein25228019
C005273naringeninnaringenin inhibits the reaction [Cadmium Chloride results in decreased expression of G6PD protein]19063931
C005273naringeninnaringenin results in decreased activity of G6PD protein25228019
C005274naringinnaringin affects the reaction [LEPR protein affects the activity of G6PD protein]16427799
C005274naringinnaringin inhibits the reaction [nickel sulfate results in decreased activity of G6PD protein]20950607
C026385n-hexanen-hexane results in increased expression of G6PD mRNA20566472
D009532NickelNickel results in decreased activity of G6PD protein22534063
D009532NickelNickel results in increased activity of G6PD protein22444726|2253406
C022838nickel chloridenickel chloride affects the expression of G6PD mRNA22546817
C028007nickel monoxidenickel monoxide results in increased expression of G6PD mRNA19167457
C029938nickel sulfatenickel sulfate results in increased expression of G6PD mRNA20566472
C029938nickel sulfatenaringin inhibits the reaction [nickel sulfate results in decreased activity of G6PD protein]20950607
C029938nickel sulfatenickel sulfate results in decreased activity of G6PD protein20950607
D009538NicotineNicotine results in decreased activity of G6PD protein20498001
D009582NitrofurantoinNitrofurantoin results in decreased activity of G6PD protein11856576
D009599NitroprussideZinc Sulfate promotes the reaction [Nitroprusside results in increased expression of G6PD mRNA]17018880
C044387N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine"N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of G6PD mRNA"12888634|1701888
C025256nonylphenolnonylphenol results in decreased expression of G6PD mRNA22982499
C025256nonylphenolnonylphenol results in decreased expression of G6PD protein19260726
D009638NorepinephrineMetoprolol inhibits the reaction [Norepinephrine results in increased activity of G6PD protein]1378361
D009638NorepinephrineNorepinephrine results in increased activity of G6PD mRNA1378361
D009638NorepinephrineNorepinephrine results in increased activity of G6PD protein7605896
D009638NorepinephrineNorepinephrine results in increased expression of G6PD mRNA7605896
D009638NorepinephrinePrazosin inhibits the reaction [Norepinephrine results in increased activity of G6PD protein]1378361
C005310norfenefrinenorfenefrine results in increased activity of G6PD protein1378361
C005310norfenefrinePrazosin inhibits the reaction [norfenefrine results in increased activity of G6PD protein]1378361
C423264(N-propargyl-(3R) aminoindan-5-yl)-ethyl methyl carbamate(N-propargyl-(3R) aminoindan-5-yl)-ethyl methyl carbamate results in increased expression of G6PD mRNA18598687
C558013NSC 689534[NSC 689534 binds to Copper] which results in decreased expression of G6PD mRNA20971185
C062198octa-2,4,6-trienoic acid"octa-2,4,6-trienoic acid results in decreased expression of G6PD mRNA"16951191
C108709oleoyl-estroneoleoyl-estrone results in decreased expression of G6PD mRNA17725831
C009897O,O-diisopropyl-S-benzylthiophosphate"O,O-diisopropyl-S-benzylthiophosphate results in decreased expression of G6PD mRNA"18983944
C009897O,O-diisopropyl-S-benzylthiophosphate"O,O-diisopropyl-S-benzylthiophosphate results in increased expression of G6PD mRNA"18983944
D010100OxygenAcetylcysteine inhibits the reaction [Oxygen deficiency results in increased expression of G6PD mRNA]15225644
D010100OxygenGlutathione inhibits the reaction [Oxygen deficiency results in increased expression of G6PD mRNA]15225644
D010100OxygenOxygen deficiency results in increased activity of G6PD protein15225644
D010100OxygenOxygen deficiency results in increased expression of G6PD mRNA15225644
D010100OxygenS-ethyl glutathione inhibits the reaction [Oxygen deficiency results in increased expression of G6PD mRNA]15225644
D010269ParaquatParaquat affects the expression of G6PD mRNA25064622
D010269ParaquatParaquat results in increased activity of G6PD protein12453665
D010269ParaquatParaquat results in increased activity of G6PD protein10036331
D010269ParaquatParaquat affects the activity of G6PD protein11814328
D010269ParaquatParaquat results in increased activity of G6PD protein7522492
D010575PesticidesPesticides results in increased activity of G6PD protein23820267
C031181phenanthrenephenanthrene results in increased expression of G6PD mRNA19457238
D010634Phenobarbital[Diethylnitrosamine co-treated with Phenobarbital] results in decreased activity of G6PD protein16188247
D010634PhenobarbitalPlant Extracts inhibits the reaction [[Diethylnitrosamine co-treated with Phenobarbital] results in decreased activity of G6PD protein]16188247
D010662Phenylmercuric Acetate"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of G6PD mRNA"27188386
D010662Phenylmercuric AcetatePhenylmercuric Acetate results in increased expression of G6PD mRNA26272509
D010833Phytic Acid[Phytic Acid co-treated with Inositol] inhibits the reaction [Streptozocin results in decreased activity of G6PD protein]28757134
D010882Piperonyl Butoxide[Diethylnitrosamine co-treated with Piperonyl Butoxide] results in increased expression of G6PD protein28903497
D010936Plant ExtractsPlant Extracts inhibits the reaction [Benzoyl Peroxide results in decreased activity of G6PD protein]15629248
D010936Plant ExtractsPlant Extracts inhibits the reaction [Cadmium Chloride results in decreased activity of G6PD protein]23961183
D010936Plant ExtractsPlant Extracts inhibits the reaction [[Diethylnitrosamine co-treated with Phenobarbital] results in decreased activity of G6PD protein]16188247
D010936Plant ExtractsPlant Extracts inhibits the reaction [[Malathion co-treated with Carbaryl] results in increased activity of G6PD protein]27214522
D010936Plant ExtractsPlant Extracts results in increased activity of G6PD protein16188247
C058229polydatinpolydatin results in decreased activity of G6PD protein25130191
C019536potassium bromatepotassium bromate results in decreased activity of G6PD protein25213677
C019536potassium bromateTaurine inhibits the reaction [potassium bromate results in decreased activity of G6PD protein]25213677
C027373potassium chromate(VI)potassium chromate(VI) results in decreased activity of G6PD protein7753043
D011192Potassium DichromatePotassium Dichromate results in decreased activity of G6PD protein21681464
D011192Potassium DichromatePotassium Dichromate results in decreased activity of G6PD protein1512015
D011224PrazosinPrazosin inhibits the reaction [Norepinephrine results in increased activity of G6PD protein]1378361
D011224PrazosinPrazosin inhibits the reaction [norfenefrine results in increased activity of G6PD protein]1378361
D011319PrimaquineG6PD protein affects the susceptibility to Primaquine19616568
D011319PrimaquineG6PD protein results in decreased susceptibility to Primaquine22330256
D011374ProgesteroneProgesterone results in increased expression of G6PD mRNA23012394
D011398PromethazinePromethazine results in increased expression of G6PD mRNA28903497
D0198402-Propanol2-Propanol results in increased expression of G6PD mRNA20566472
C035967propetamphos[cypermethrin co-treated with propetamphos] results in decreased activity of G6PD protein25926273
C035967propetamphospropetamphos results in decreased activity of G6PD protein25926273
D011758PyrrolesPyrroles results in increased activity of G6PD protein1901343
D011794QuercetinQuercetin results in increased expression of G6PD mRNA21632981
D011794QuercetinQuercetin analog inhibits the reaction [sodium arsenite results in decreased activity of G6PD protein]20371363
D011794QuercetinQuercetin inhibits the reaction [Cadmium results in decreased expression of G6PD protein]19615871
C009145quinalphos[Monocrotophos co-treated with quinalphos] affects the activity of G6PD protein24248738
C009145quinalphosquinalphos affects the activity of G6PD protein24248738
C502851quinocetonequinocetone results in decreased expression of G6PD mRNA27046791
C502851quinocetonequinocetone results in decreased expression of G6PD protein27046791
C502851quinocetonequinocetone results in increased expression of G6PD protein27046791
C052785rebamipiderebamipide results in increased expression of G6PD mRNA18299717
C059514resveratrolresveratrol inhibits the reaction [[Streptozocin co-treated with Niacinamide] affects the activity of G6PD protein]19059388
C059514resveratrolresveratrol results in decreased activity of G6PD protein24012391
D015474IsotretinoinIsotretinoin results in decreased expression of G6PD mRNA20436886
D015474IsotretinoinIsotretinoin results in increased expression of G6PD mRNA15982314
D015474IsotretinoinIsotretinoin inhibits the reaction [Benzoyl Peroxide results in decreased activity of G6PD protein]15225900
C089730rosiglitazonerosiglitazone results in increased expression of G6PD mRNA19201733
C078903seocalcitolseocalcitol results in increased expression of G6PD mRNA12040012
D017632Asbestos, Serpentine"Asbestos, Serpentine results in decreased activity of G6PD protein"16039947|1837041
D017632Asbestos, Serpentine"[Kerosene co-treated with Asbestos, Serpentine] results in increased activity of G6PD protein"9177657
D017632Asbestos, Serpentine"[Soot co-treated with Asbestos, Serpentine] results in increased activity of G6PD protein"9177657
C042431S-ethyl glutathioneS-ethyl glutathione inhibits the reaction [Cadmium Chloride results in increased expression of G6PD mRNA]12717738
C042431S-ethyl glutathioneS-ethyl glutathione inhibits the reaction [Oxygen deficiency results in increased expression of G6PD mRNA]15225644
D012822Silicon DioxideSilicon Dioxide analog affects the secretion of G6PD protein25895662
D012822Silicon DioxideSilicon Dioxide analog results in decreased expression of G6PD mRNA25895662
D012834SilverSilver results in increased expression of G6PD mRNA18394669
D012835Silver NitrateSilver Nitrate results in decreased activity of G6PD protein23363574
D012835Silver NitrateSilver Nitrate results in decreased activity of G6PD protein28557068
C440975silybinsilybin inhibits the reaction [Arsenic results in decreased activity of G6PD protein]22229868
D012838Silymarin[essential 303 forte co-treated with Silymarin] affects the activity of G6PD protein25903262
D012838Silymarin[essential 303 forte co-treated with Silymarin co-treated with Melatonin analog] affects the activity of G6PD protein25903262
C073734sinapinic acidsinapinic acid results in decreased activity of G6PD protein25130191
C017947sodium arsenitesodium arsenite affects the methylation of G6PD gene28589171
C017947sodium arsenitesodium arsenite results in increased expression of G6PD mRNA25493608|2728725
C017947sodium arsenitesodium arsenite results in increased expression of G6PD protein24866292|2871322
C017947sodium arsenitesodium arsenite results in increased expression of G6PD protein24866292
C017947sodium arsenitesodium arsenite inhibits the reaction [Sodium Fluoride results in decreased activity of G6PD protein]19635623
C017947sodium arsenitesodium arsenite results in decreased activity of G6PD protein19635623
C017947sodium arseniteSodium Fluoride inhibits the reaction [sodium arsenite results in decreased activity of G6PD protein]19635623
C017947sodium arseniteVitamin E inhibits the reaction [sodium arsenite results in decreased activity of G6PD protein]19635623
C017947sodium arseniteQuercetin analog inhibits the reaction [sodium arsenite results in decreased activity of G6PD protein]20371363
C017947sodium arsenitesodium arsenite results in decreased activity of G6PD protein20371363
C017947sodium arsenitesodium arsenite results in increased activity of G6PD protein10996542
C032706sodium chloratesodium chlorate results in decreased activity of G6PD protein28084674
D012967Sodium Dodecyl SulfateSodium Dodecyl Sulfate results in increased expression of G6PD mRNA20566472
D012969Sodium Fluoridesodium arsenite inhibits the reaction [Sodium Fluoride results in decreased activity of G6PD protein]19635623
D012969Sodium FluorideSodium Fluoride inhibits the reaction [sodium arsenite results in decreased activity of G6PD protein]19635623
D012969Sodium FluorideSodium Fluoride results in decreased activity of G6PD protein19635623
C031618sodium nitratesodium nitrate results in decreased activity of G6PD protein19922758
D012977Sodium NitriteSodium Nitrite results in decreased activity of G6PD protein26231821
D012989Soil PollutantsSoil Pollutants results in decreased activity of G6PD protein10706032
D053260Soot[Soot co-treated with Benzo(a)pyrene] results in increased expression of G6PD protein24464499
D053260Soot"[Soot co-treated with Asbestos, Serpentine] results in increased activity of G6PD protein"9177657
C539817S-sulindacS-sulindac results in increased expression of G6PD mRNA19276279
D013311Streptozocin4-hydroxyphenylethanol inhibits the reaction [Streptozocin results in decreased activity of G6PD protein]25641191
D013311Streptozocinarjunolic acid inhibits the reaction [Streptozocin results in decreased activity of G6PD protein]19133311|1968244
D013311Streptozocincitronellol inhibits the reaction [Streptozocin results in decreased activity of G6PD protein]26944432
D013311StreptozocinGlyburide inhibits the reaction [Streptozocin results in decreased activity of G6PD protein]25641191
D013311Streptozocinmyricetin inhibits the reaction [[Streptozocin co-treated with Cadmium] results in decreased activity of G6PD protein]24923654
D013311Streptozocin[Phytic Acid co-treated with Inositol] inhibits the reaction [Streptozocin results in decreased activity of G6PD protein]28757134
D013311Streptozocinresveratrol inhibits the reaction [[Streptozocin co-treated with Niacinamide] affects the activity of G6PD protein]19059388
D013311Streptozocin[Streptozocin co-treated with Cadmium] results in decreased activity of G6PD protein24923654
D013311Streptozocin[Streptozocin co-treated with Niacinamide] affects the activity of G6PD protein19059388
D013311StreptozocinStreptozocin results in decreased activity of G6PD protein19133311|1968244
C016766sulforafansulforafan results in increased expression of G6PD mRNA26833863
D013605T-2 ToxinT-2 Toxin affects the expression of G6PD protein26141394
D013605T-2 ToxinT-2 Toxin results in decreased expression of G6PD mRNA26141394
D000068581TadalafilTadalafil results in increased activity of G6PD protein24911673
D013629TamoxifenTamoxifen affects the expression of G6PD mRNA14699072
D013654TaurineTaurine inhibits the reaction [Cadmium Chloride results in decreased activity of G6PD protein]18414974|1856190
D013654TaurineTaurine inhibits the reaction [potassium bromate results in decreased activity of G6PD protein]25213677
D013726TerbutalineTerbutaline results in increased activity of G6PD protein1978808
D013739Testosterone[Testosterone co-treated with Calcitriol] results in increased expression of G6PD mRNA21592394
D013739TestosteroneTestosterone results in increased expression of G6PD mRNA21592394
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of G6PD mRNA22298810
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of G6PD mRNA16054898|2121527
D013752TetracyclineTetracycline affects the expression of G6PD mRNA25064622
D013755Tetradecanoylphorbol Acetate[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of G6PD mRNA25613284
D013849ThimerosalThimerosal results in decreased expression of G6PD mRNA27188386
D013853ThioacetamideThioacetamide affects the expression of G6PD mRNA25064622
D013853Thioacetamide[Diethylnitrosamine co-treated with Thioacetamide] results in increased expression of G6PD protein28903497
D013853ThioacetamideThioacetamide results in increased expression of G6PD mRNA23411599|2890349
D013890ThioureaThiourea results in increased activity of G6PD protein12658717
D013890ThioureaThyroxine inhibits the reaction [Thiourea results in increased activity of G6PD protein]12658717
D013974ThyroxineThyroxine inhibits the reaction [Thiourea results in increased activity of G6PD protein]12658717
C009495titanium dioxide[Vitallium analog binds to titanium dioxide] which results in increased expression of G6PD mRNA23825117
D014028Tobacco Smoke PollutionTobacco Smoke Pollution results in decreased expression of G6PD mRNA28065790
D014212TretinoinTretinoin metabolite results in increased expression of G6PD mRNA15982314
D014212TretinoinTretinoin results in increased expression of G6PD mRNA15982314
C057693troglitazonetroglitazone results in increased expression of G6PD mRNA28973697
C080163trovafloxacintrovafloxacin results in decreased expression of G6PD mRNA24136188
D014635Valproic AcidValproic Acid affects the expression of G6PD mRNA25064622
D014635Valproic AcidValproic Acid affects the expression of G6PD mRNA25979313
D014635Valproic AcidValproic Acid results in increased expression of G6PD mRNA25399406|2915479
D014635Valproic AcidValproic Acid results in increased methylation of G6PD gene29154799
C025643vinclozolinvinclozolin results in decreased expression of G6PD mRNA23034163
D014800Vitallium[Vitallium analog binds to titanium dioxide] which results in increased expression of G6PD mRNA23825117
D014800VitalliumVitallium analog results in increased expression of G6PD mRNA23825117
D009536Niacinamideresveratrol inhibits the reaction [[Streptozocin co-treated with Niacinamide] affects the activity of G6PD protein]19059388
D009536Niacinamide[Streptozocin co-treated with Niacinamide] affects the activity of G6PD protein19059388
D014810Vitamin EVitamin E inhibits the reaction [sodium arsenite results in decreased activity of G6PD protein]19635623
C111237vorinostatvorinostat results in decreased expression of G6PD mRNA27188386
D014874Water Pollutants, Chemical"Water Pollutants, Chemical results in increased activity of G6PD protein"25179371
D015032ZincZinc results in decreased activity of G6PD protein26602879
D015032ZincZinc results in decreased expression of G6PD mRNA26602879
D015032ZincZinc results in increased expression of G6PD mRNA17948801|1839466
D015032Zinc[Cadmium co-treated with Zinc] results in increased activity of G6PD protein20143450
D015032ZincZinc results in increased activity of G6PD protein20143450
D015032ZincZinc affects the activity of G6PD protein17181878
C016837zinc chloridezinc chloride results in increased expression of G6PD mRNA19683351
C016837zinc chloridezinc chloride inhibits the reaction [Cadmium Chloride results in decreased activity of G6PD protein]18972399
C042103zinc nitratezinc nitrate results in decreased activity of G6PD protein28557068
D019287Zinc SulfateZinc Sulfate promotes the reaction [Nitroprusside results in increased expression of G6PD mRNA]17018880
D019287Zinc SulfateZinc Sulfate results in increased expression of G6PD mRNA17018880
D019287Zinc Sulfate[Zinc Sulfate co-treated with Hydrogen Peroxide] results in increased expression of G6PD mRNA15922008
D019287Zinc SulfateZinc Sulfate results in increased expression of G6PD mRNA15922008

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0004345glucose-6-phosphate dehydrogenase activity-EXP10745013  
GO:0004345glucose-6-phosphate dehydrogenase activity-IDA15858258  
GO:0004345glucose-6-phosphate dehydrogenase activity-IMP743300  2420826  5643703  
GO:0005515protein binding-IPI21157431  24769394  
GO:0005536glucose binding-IDA15858258  
GO:0005536glucose binding-IMP5643703  
GO:0042802identical protein binding-IPI24769394  25416956  
GO:0042803protein homodimerization activity-IPI15858258  
GO:0050661NADP binding-IDA15858258  
GO ID GO Term Qualifier Evidence PubMed
GO:0006006glucose metabolic process-IEA-  
GO:0006098pentose-phosphate shunt-IDA2297768  
GO:0006098pentose-phosphate shunt-TAS-  
GO:0006629lipid metabolic process-TAS17361089  
GO:0006695cholesterol biosynthetic process-IMP12027950  
GO:0006739NADP metabolic process-IDA15858258  
GO:0006740NADPH regeneration-IMP17516514  
GO:0006749glutathione metabolic process-IMP2420826  17516514  
GO:0009051pentose-phosphate shunt, oxidative branch-IMP2420826  
GO:0010041response to iron(III) ion-IEA-  
GO:0010734negative regulation of protein glutathionylation-IMP17516514  
GO:0014070response to organic cyclic compound-IEA-  
GO:0019322pentose biosynthetic process-IDA5643703  
GO:0021762substantia nigra development-HEP22926577  
GO:0032094response to food-IEA-  
GO:0034599cellular response to oxidative stress-IMP17516514  
GO:0043249erythrocyte maturation-IMP5643703  
GO:0043523regulation of neuron apoptotic process-IEA-  
GO:0045471response to ethanol-IEA-  
GO:0046390ribose phosphate biosynthetic process-IMP2420826  
GO:0051156glucose 6-phosphate metabolic process-IDA15858258  
GO:0051156glucose 6-phosphate metabolic process-IMP5643703  
GO:0055114oxidation-reduction process-IMP2420826  
GO:0061052negative regulation of cell growth involved in cardiac muscle cell development-IEA-  
GO:1904879positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel-IEA-  
GO:2000378negative regulation of reactive oxygen species metabolic process-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO:0005634nucleus-IEA-  
GO:0005737cytoplasm-IDA-  
GO:0005829cytosol-IDA743300  
GO:0005829cytosol-TAS-  
GO:0009898cytoplasmic side of plasma membrane-IDA743300  
GO:0016020membrane-HDA19946888  
GO:0070062extracellular exosome-HDA19056867  23533145  
KEGG ID KEGG Term
hsa00030Pentose phosphate pathway
hsa00480Glutathione metabolism
hsa01100Metabolic pathways
Reactome ID Reactome Term Evidence
R-HSA-1430728MetabolismTAS
R-HSA-212436Generic Transcription PathwayTAS
R-HSA-3700989Transcriptional Regulation by TP53TAS
R-HSA-5628897TP53 Regulates Metabolic GenesTAS
R-HSA-71336Pentose phosphate pathway (hexose monophosphate shunt)TAS
R-HSA-71387Metabolism of carbohydratesTAS
R-HSA-73857RNA Polymerase II TranscriptionTAS
R-HSA-74160Gene expression (Transcription)TAS

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
18671841PSMB2 and RPL32 are suitable denominators to normalize gene expression profiles in bronchoalveolar cells. (2008 Jul 31)Kriegova EBMC Mol Biol
25392263Epidemiology and Associated Morbidity of Pterygium: A Large, Community-Based Case-Control Study. (2016)Nemet AYSemin Ophthalmol
26988295The influence of chronic nicotine treatment on proteins expressed in the mouse hippocampus and cortex. (2016 Jun 5)Matsuura KEur J Pharmacol
17784549[Red cell system and selected red cell enzymes in men occupationally exposed to mercury vapours]. (2006)Zabinski ZPrzegl Lek
11355791The epidemiology of recurrent pregnancy loss. (2000)Cramer DWSemin Reprod Med
27858887Glucose-6-phosphate dehydrogenase deficiency and risk of colorectal cancer in Northern Sardinia: A retrospective observational study. (2016 Nov)Dore MPMedicine (Baltimore)
8935483Liver involvement in murine typhus. (1996 Aug)Silpapojakul KQJM