Gene: GABRA6

2559
-
gamma-aminobutyric acid type A receptor alpha6 subunit
protein-coding
5q34
Ensembl:ENSG00000145863 MIM:137143 Vega:OTTHUMG00000130351 UniprotKB:Q16445
NC_000005.10
PubMed
AD
9   
NA (AD)  NA (ND)   (Frontal_Cortex)
8.469e-1 (AD)  6.879e-1 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
ANKRD36C0.736
ZNF3820.724
AHI10.721
SLC26A40.721
ODF2L0.717
ABCA50.717
ARMCX40.713
ABCA100.711
TARBP10.705
BHLHE220.705

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
CCDC102A-0.449
FOXJ1-0.407
AKR1C3-0.391
ROM1-0.382
EVC2-0.381
PPP1R14B-0.377
NKX2-2-0.374
WDR38-0.371
KIF1C-0.367
INHBB-0.364

Drugs/Compounds

ID Drug Name Drug Type CAS Num Status Role
DB00231TemazepamSmall Molecule846-50-4Approved|InvestigationalTarget
DB00241ButalbitalSmall Molecule77-26-9Approved|IllicitTarget
DB00306TalbutalSmall Molecule115-44-6Approved|IllicitTarget
DB00312PentobarbitalSmall Molecule76-74-4Approved|InvestigationalTarget
DB00371MeprobamateSmall Molecule57-53-4Approved|IllicitTarget
DB00418SecobarbitalSmall Molecule76-73-3ApprovedTarget
DB00463MetharbitalSmall Molecule50-11-3WithdrawnTarget
DB00599ThiopentalSmall Molecule76-75-5ApprovedTarget
DB00683MidazolamSmall Molecule59467-70-8Approved|IllicitTarget
DB00690FlurazepamSmall Molecule17617-23-1Approved|Illicit|InvestigationalTarget
DB00794PrimidoneSmall Molecule125-33-7ApprovedTarget
DB00842OxazepamSmall Molecule604-75-1ApprovedTarget
DB00849MethylphenobarbitalSmall Molecule115-38-8ApprovedTarget
DB00897TriazolamSmall Molecule28911-01-5Approved|InvestigationalTarget
DB00898EthanolSmall Molecule64-17-5ApprovedTarget
DB01351AmobarbitalSmall Molecule57-43-2Approved|IllicitTarget
DB01352AprobarbitalSmall Molecule77-02-1Approved|IllicitTarget
DB01353ButethalSmall Molecule77-28-1Approved|IllicitTarget
DB01354HeptabarbitalSmall Molecule509-86-4ApprovedTarget
DB01355HexobarbitalSmall Molecule56-29-1ApprovedTarget
DB01483BarbitalSmall Molecule57-44-3IllicitTarget
DB01496Barbituric acid derivativeSmall MoleculeExperimental|IllicitTarget
DB01544FlunitrazepamSmall Molecule1622-62-4Approved|IllicitTarget
DB01558BromazepamSmall Molecule1812-30-2Approved|Illicit|InvestigationalTarget
DB01595NitrazepamSmall Molecule146-22-5ApprovedTarget
DB05087GanaxoloneSmall Molecule38398-32-2InvestigationalTarget
DB00186LorazepamSmall Molecule846-49-1ApprovedTarget
DB00189EthchlorvynolSmall Molecule113-18-8Approved|Illicit|WithdrawnTarget
DB00228EnfluraneSmall Molecule13838-16-9Approved|InvestigationalTarget
DB00231TemazepamSmall Molecule846-50-4Approved|InvestigationalTarget
DB00237ButabarbitalSmall Molecule125-40-6Approved|IllicitTarget
DB00241ButalbitalSmall Molecule77-26-9Approved|IllicitTarget
DB00273TopiramateSmall Molecule97240-79-4ApprovedTarget
DB00292EtomidateSmall Molecule33125-97-2ApprovedTarget
DB00306TalbutalSmall Molecule115-44-6Approved|IllicitTarget
DB00312PentobarbitalSmall Molecule76-74-4Approved|InvestigationalTarget
DB00334OlanzapineSmall Molecule132539-06-1Approved|InvestigationalTarget
DB00349ClobazamSmall Molecule22316-47-8Approved|IllicitTarget
DB00371MeprobamateSmall Molecule57-53-4Approved|IllicitTarget
DB00402EszopicloneSmall Molecule138729-47-2Approved|InvestigationalTarget
DB00404AlprazolamSmall Molecule28981-97-7Approved|Illicit|InvestigationalTarget
DB00463MetharbitalSmall Molecule50-11-3WithdrawnTarget
DB00475ChlordiazepoxideSmall Molecule58-25-3Approved|Illicit|InvestigationalTarget
DB00543AmoxapineSmall Molecule14028-44-5ApprovedTarget
DB00555LamotrigineSmall Molecule84057-84-1Approved|InvestigationalTarget
DB00628ClorazepateSmall Molecule23887-31-2Approved|IllicitTarget
DB00659AcamprosateSmall Molecule77337-76-9Approved|InvestigationalTarget
DB00753IsofluraneSmall Molecule26675-46-7ApprovedTarget
DB00794PrimidoneSmall Molecule125-33-7ApprovedTarget
DB00801HalazepamSmall Molecule23092-17-3Approved|Illicit|WithdrawnTarget
DB00818PropofolSmall Molecule2078-54-8Approved|InvestigationalTarget
DB00829DiazepamSmall Molecule439-14-5Approved|Illicit|InvestigationalTarget
DB00842OxazepamSmall Molecule604-75-1ApprovedTarget
DB00897TriazolamSmall Molecule28911-01-5Approved|InvestigationalTarget
DB01028MethoxyfluraneSmall Molecule76-38-0Approved|InvestigationalTarget
DB01049Ergoloid mesylateSmall Molecule8067-24-1ApprovedTarget
DB01068ClonazepamSmall Molecule1622-61-3Approved|IllicitTarget
DB01107MethyprylonSmall Molecule125-64-4Approved|Illicit|WithdrawnTarget
DB01159HalothaneSmall Molecule151-67-7ApprovedTarget
DB01189DesfluraneSmall Molecule57041-67-5ApprovedTarget
DB01205FlumazenilSmall Molecule78755-81-4ApprovedTarget
DB01215EstazolamSmall Molecule29975-16-4Approved|IllicitTarget
DB01236SevofluraneSmall Molecule28523-86-6ApprovedTarget
DB01437GlutethimideSmall Molecule77-21-4Approved|IllicitTarget
DB01588PrazepamSmall Molecule2955-38-6Approved|IllicitTarget
DB01589QuazepamSmall Molecule36735-22-5Approved|IllicitTarget
DB01708PrasteroneSmall Molecule53-43-0Approved|Investigational|NutraceuticalTarget
DB01956TaurineSmall Molecule107-35-7Approved|NutraceuticalTarget
DB09118StiripentolSmall Molecule49763-96-4ApprovedTarget
DB11582ThiocolchicosideSmall Molecule602-41-5Approved|InvestigationalTarget
DB11901ApalutamideSmall Molecule956104-40-8Approved|InvestigationalTarget
DB00555LamotrigineSmall Molecule84057-84-1Approved|InvestigationalTarget
DB06579AdipiplonSmall Molecule840486-93-3InvestigationalTarget
DB139835,7,2G??-trihydroxy-6,8-dimethoxyflavoneSmall Molecule159359-22-5ExperimentalTarget
ID Drug Name Action PubMed
C043877acamprosateGABRA6 affects the susceptibility to acamprosate19523047
D000082AcetaminophenAcetaminophen results in increased expression of GABRA6 mRNA26690555
D016604Aflatoxin B1Aflatoxin B1 results in decreased methylation of GABRA6 gene27153756
D005680gamma-Aminobutyric Aciddelta-hexachlorocyclohexane promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA6 protein binds to GABRB3 protein binds to GABRG2 protein]]9316872
D005680gamma-Aminobutyric AcidFlumazenil promotes the reaction [gamma-Aminobutyric Acid binds to and results in increased activity of [GABRA6 protein binds to GABRB3 protein binds to GABRG2 protein]]8632757
D005680gamma-Aminobutyric Acidgamma-Aminobutyric Acid results in increased activity of [GABRA6 protein binds to GABRB1 protein binds to GABRG2 protein alternative form]29038840
D005680gamma-Aminobutyric Acidgamma-Aminobutyric Acid results in increased activity of [GABRA6 protein binds to GABRB2 protein binds to GABRG2 protein alternative form]29038840
D005680gamma-Aminobutyric Acidgamma-Aminobutyric Acid results in increased activity of [GABRA6 protein binds to GABRB3 protein binds to GABRD protein]29038840
D005680gamma-Aminobutyric Acidgamma-Aminobutyric Acid results in increased activity of [GABRA6 protein binds to GABRB3 protein binds to GABRG1 protein]29038840
D005680gamma-Aminobutyric Acidgamma-Aminobutyric Acid results in increased activity of [GABRA6 protein binds to GABRB3 protein binds to GABRG2 protein]9316872
D005680gamma-Aminobutyric Acidgamma-Aminobutyric Acid results in increased activity of [GABRA6 protein binds to GABRB3 protein binds to GABRG2 protein alternative form]29038840
D005680gamma-Aminobutyric AcidLindane inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA6 protein binds to GABRB3 protein binds to GABRG2 protein]]9316872
D005680gamma-Aminobutyric Acidpicrotoxinin inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA6 protein binds to GABRB2 protein binds to GABRG2 protein alternative form]]29038840
D005680gamma-Aminobutyric Acidpicrotoxinin inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA6 protein binds to GABRB3 protein binds to GABRG2 protein alternative form]]29038840
D005680gamma-Aminobutyric AcidRo 15-4513 promotes the reaction [gamma-Aminobutyric Acid binds to and results in increased activity of [GABRA6 protein binds to GABRB3 protein binds to GABRG2 protein]]8632757
D005680gamma-Aminobutyric Acidtetramethylenedisulfotetramine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA6 protein binds to GABRB3 protein binds to GABRD protein]]29038840
D005680gamma-Aminobutyric Acidtetramethylenedisulfotetramine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA6 protein binds to GABRB3 protein binds to GABRG2 protein alternative form]]29038840
D005680gamma-Aminobutyric AcidBicuculline inhibits the reaction [methylmercuric chloride promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA6 protein binds to GABRB2 protein binds to GABRG2 protein]]]27720918
D005680gamma-Aminobutyric Acidgamma-Aminobutyric Acid results in increased activity of [GABRA6 protein binds to GABRB2 protein binds to GABRG2 protein]27720918
D005680gamma-Aminobutyric Acidgamma-Aminobutyric Acid results in increased activity of [GABRA6 protein co-treated with GABRB2 protein co-treated with GABRG2 protein]11123204
D005680gamma-Aminobutyric Acid[gamma-Aminobutyric Acid results in increased activity of [GABRA6 protein co-treated with GABRB2 protein co-treated with GABRG2 protein]] which results in increased transport of Chlorides11123204
D005680gamma-Aminobutyric Acidmethylmercuric chloride promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA6 protein binds to GABRB2 protein binds to GABRG2 protein]]27720918
D005680gamma-Aminobutyric AcidNiflumic Acid inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA6 protein binds to GABRB2 protein binds to GABRG2 protein]]27720918
D005680gamma-Aminobutyric Acidtopiramate promotes the reaction [[gamma-Aminobutyric Acid results in increased activity of [GABRA6 protein co-treated with GABRB2 protein co-treated with GABRG2 protein]] which results in increased transport of Chlorides]11123204
D000643Ammonium ChlorideAmmonium Chloride affects the expression of GABRA6 mRNA16483693
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of GABRA6 mRNA22316170
D001640BicucullineBicuculline results in decreased activity of [GABRA6 protein binds to GABRB1 binds to GABRG2 protein alternative form]29038840
D001640BicucullineBicuculline results in decreased activity of [GABRA6 protein binds to GABRB3 binds to GABRG2 protein alternative form]29038840
D001640BicucullineBicuculline inhibits the reaction [methylmercuric chloride promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA6 protein binds to GABRB2 protein binds to GABRG2 protein]]]27720918
C006780bisphenol Abisphenol A results in decreased expression of GABRA6 mRNA25181051
C054626bretazenilbretazenil binds to and results in increased activity of [GABRA6 protein binds to GABRB3 protein binds to GABRG2 protein]8632757
D002104CadmiumCadmium results in decreased expression of GABRA6 mRNA24376830
D002220CarbamazepineCarbamazepine affects the expression of GABRA6 mRNA25979313
C010063carbonyl sulfidecarbonyl sulfide results in increased expression of GABRA6 mRNA19395590
D002330CarmustineCarmustine results in decreased expression of GABRA6 mRNA15980968
D002712Chlorides[gamma-Aminobutyric Acid results in increased activity of [GABRA6 protein co-treated with GABRB2 protein co-treated with GABRG2 protein]] which results in increased transport of Chlorides11123204
D002712Chloridestopiramate promotes the reaction [[gamma-Aminobutyric Acid results in increased activity of [GABRA6 protein co-treated with GABRB2 protein co-treated with GABRG2 protein]] which results in increased transport of Chlorides]11123204
D005576ColforsinColforsin results in decreased expression of GABRA69147380
C086916delta-hexachlorocyclohexanedelta-hexachlorocyclohexane promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA6 protein binds to GABRB3 protein binds to GABRG2 protein]]9316872
C086916delta-hexachlorocyclohexanedelta-hexachlorocyclohexane results in increased activity of [GABRA6 protein binds to GABRB3 protein binds to GABRG2 protein]9316872
D013759DronabinolDronabinol results in decreased expression of GABRA6 mRNA16616335
D003975DiazepamGABRA6 gene results in decreased susceptibility to Diazepam9987027
D003975DiazepamGABRA6 protein results in decreased susceptibility to Diazepam9281599
D003975DiazepamDiazepam results in increased expression of GABRA6 mRNA15802192
D000431EthanolEthanol deficiency results in decreased expression of GABRA6 mRNA17403139
C047360felbamatefelbamate results in decreased activity of [GABRA6 protein binds to GABRB1 protein binds to GABRG2 protein alternative form]17056029
C082360fipronilfipronil results in decreased activity of [GABRA6 protein binds to GABRB1 binds to GABRG2 protein alternative form]29038840
C082360fipronilfipronil results in decreased activity of [GABRA6 protein binds to GABRB2 binds to GABRG2 protein alternative form]29038840
C082360fipronilfipronil results in decreased activity of [GABRA6 protein binds to GABRB3 binds to GABRG2 protein alternative form]29038840
D005442FlumazenilFlumazenil binds to and results in increased activity of [GABRA6 protein binds to GABRB3 protein binds to GABRG2 protein]8632757
D005442FlumazenilFlumazenil binds to [GABRA6 protein binds to GABRB3 protein binds to GABRG2 protein]8632757
D005442FlumazenilFlumazenil promotes the reaction [gamma-Aminobutyric Acid binds to and results in increased activity of [GABRA6 protein binds to GABRB3 protein binds to GABRG2 protein]]8632757
D005492Folic AcidFolic Acid results in increased expression of GABRA6 mRNA25006883
D005665FurosemideFurosemide binds to and results in decreased activity of GABRA6 protein12367619
D018682GABA AgentsGABA Agents binds to and results in increased activity of [GABRA6 protein binds to GABRB3 protein binds to GABRG2 protein]8632757
C063822L 663581L 663581 binds to and results in increased activity of [GABRA6 protein binds to GABRB3 protein binds to GABRG2 protein]8632757
D001556LindaneLindane inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA6 protein binds to GABRB3 protein binds to GABRG2 protein]]9316872
D008344Maneb[Paraquat co-treated with Maneb] affects the expression of GABRA6 mRNA22563483
D008628MercuryMercury results in increased expression of GABRA6 mRNA16823088
C004925methylmercuric chlorideBicuculline inhibits the reaction [methylmercuric chloride promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA6 protein binds to GABRB2 protein binds to GABRG2 protein]]]27720918
C004925methylmercuric chloridemethylmercuric chloride promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA6 protein binds to GABRB2 protein binds to GABRG2 protein]]27720918
D008874MidazolamGABRA6 protein mutant form results in decreased susceptibility to Midazolam12031754
D009271NaltrexoneGABRA6 affects the susceptibility to Naltrexone19523047
D009544Niflumic AcidNiflumic Acid inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA6 protein binds to GABRB2 protein binds to GABRG2 protein]]27720918
D010269Paraquat[Paraquat co-treated with Maneb] affects the expression of GABRA6 mRNA22563483
D010424PentobarbitalPentobarbital results in increased expression of GABRA6 mRNA8787126
C033457phenobarbital quinidinephenobarbital quinidine results in increased expression of GABRA6 mRNA15802192
C022961picrotoxininpicrotoxinin inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA6 protein binds to GABRB2 protein binds to GABRG2 protein alternative form]]29038840
C022961picrotoxininpicrotoxinin inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA6 protein binds to GABRB3 protein binds to GABRG2 protein alternative form]]29038840
C006253pirinixic acid[pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of GABRA6 mRNA19710929
D011280PregnanolonePregnanolone results in increased activity of [GABRA6 protein binds to GABRB3 binds to GABRG2 protein alternative form]29038840
D011280PregnanoloneGABRA6 protein results in increased susceptibility to Pregnanolone9281599
D015742PropofolPropofol results in increased activity of [GABRA6 protein binds to GABRB2 binds to GABRG2 protein alternative form]29038840
D015742PropofolPropofol results in increased activity of [GABRA6 protein binds to GABRB3 binds to GABRG2 protein alternative form]29038840
C042957Ro 15-4513Ro 15-4513 binds to and results in increased activity of [GABRA6 protein binds to GABRB3 protein binds to GABRG2 protein]8632757
C042957Ro 15-4513Ro 15-4513 promotes the reaction [gamma-Aminobutyric Acid binds to and results in increased activity of [GABRA6 protein binds to GABRB3 protein binds to GABRG2 protein]]8632757
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of GABRA6 mRNA21296121
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of GABRA6 protein18227101
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of GABRA6 protein18227101
C010349tetramethylenedisulfotetramineGABRA6 protein results in increased susceptibility to tetramethylenedisulfotetramine29038840
C010349tetramethylenedisulfotetraminetetramethylenedisulfotetramine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA6 protein binds to GABRB3 protein binds to GABRD protein]]29038840
C010349tetramethylenedisulfotetraminetetramethylenedisulfotetramine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA6 protein binds to GABRB3 protein binds to GABRG2 protein alternative form]]29038840
C052342topiramatetopiramate promotes the reaction [[gamma-Aminobutyric Acid results in increased activity of [GABRA6 protein co-treated with GABRB2 protein co-treated with GABRG2 protein]] which results in increased transport of Chlorides]11123204
D014635Valproic AcidValproic Acid affects the expression of GABRA6 mRNA17292431
D001335Vehicle EmissionsVehicle Emissions results in increased methylation of GABRA6 gene25560391
D015032ZincGABRA6 protein results in increased susceptibility to Zinc9281599

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0004890GABA-A receptor activityCONTRIBUTES_TOIBA21873635  
GO:0005230extracellular ligand-gated ion channel activityCONTRIBUTES_TOIBA21873635  
GO:0005230extracellular ligand-gated ion channel activity-IEA-  
GO:0005237inhibitory extracellular ligand-gated ion channel activity-IBA21873635  
GO:0005254chloride channel activity-IBA21873635  
GO:0005254chloride channel activity-IEA-  
GO:0008503benzodiazepine receptor activityCONTRIBUTES_TOIBA21873635  
GO:0008503benzodiazepine receptor activity-TAS8632757  
GO:0022851GABA-gated chloride ion channel activity-IBA21873635  
GO:1904315transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential-IBA21873635  
GO ID GO Term Qualifier Evidence PubMed
GO:0007165signal transduction-IBA21873635  
GO:0007165signal transduction-TAS8632757  
GO:0007214gamma-aminobutyric acid signaling pathway-IBA21873635  
GO:0007214gamma-aminobutyric acid signaling pathway-IEA-  
GO:0007268chemical synaptic transmission-IBA21873635  
GO:0034220ion transmembrane transport-IBA21873635  
GO:0042391regulation of membrane potential-IBA21873635  
GO:0050877nervous system process-IBA21873635  
GO:0051932synaptic transmission, GABAergic-IBA21873635  
GO:0060078regulation of postsynaptic membrane potential-IBA21873635  
GO:1902476chloride transmembrane transport-IBA21873635  
GO:1902476chloride transmembrane transport-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO:0005886plasma membrane-TAS-  
GO:0005887integral component of plasma membrane-IBA21873635  
GO:0005887integral component of plasma membrane-TAS8632757  
GO:0030054cell junction-IEA-  
GO:0032590dendrite membrane-IBA21873635  
GO:0034707chloride channel complex-IEA-  
GO:0043005neuron projection-IBA21873635  
GO:0045202synapse-IBA21873635  
GO:0045211postsynaptic membrane-IEA-  
GO:0098794postsynapse-IBA21873635  
GO:1902711GABA-A receptor complex-IBA21873635  
KEGG ID KEGG Term
hsa04080Neuroactive ligand-receptor interaction
Reactome ID Reactome Term Evidence
R-HSA-112314Neurotransmitter receptors and postsynaptic signal transmissionTAS
R-HSA-112314Neurotransmitter receptors and postsynaptic signal transmissionIEA
R-HSA-112315Transmission across Chemical SynapsesTAS
R-HSA-112315Transmission across Chemical SynapsesIEA
R-HSA-112316Neuronal SystemTAS
R-HSA-112316Neuronal SystemIEA
R-HSA-977441GABA A receptor activationTAS
R-HSA-977443GABA receptor activationTAS

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
24136292Association of gamma-aminobutyric acid A receptor alpha2 gene (GABRA2) with alcohol use disorder. (2014 Mar)Li DNeuropsychopharmacology
12555233Association of GABA(A) receptors and alcohol dependence and the effects of genetic imprinting. (2003 Feb)Song JAm J Med Genet B Neuropsychiatr Genet
19523047Predicting the effect of naltrexone and acamprosate in alcohol-dependent patients using genetic indicators. (2009 Jul)Ooteman WAddict Biol
15630072Haplotype-based localization of an alcohol dependence gene to the 5q34 {gamma}-aminobutyric acid type A gene cluster. (2005 Jan)Radel MArch Gen Psychiatry
15690551No association of the GABAA receptor genes on chromosome 5 with alcoholism in the collaborative study on the genetics of alcoholism sample. (2005 Jan 5)Dick DMAm J Med Genet B Neuropsychiatr Genet
10195814Association analysis of sequence variants of GABA(A) alpha6, beta2, and gamma2 gene cluster and alcohol dependence. (1999 Mar)Sander TAlcohol Clin Exp Res
17440936Association analysis of GABA receptor subunit genes on 5q33 with heroin dependence in a Chinese male population. (2007 Jun 5)Loh EWAm J Med Genet B Neuropsychiatr Genet
29673739Association of serotonin and GABA pathway gene polymorphisms with alcohol dependence: A preliminary study. (2018 Apr 9)Sahni SAsian J Psychiatr
16402352Negative perceived paternal parenting is associated with dopamine D2 receptor exon 8 and GABA(A) alpha 6 receptor variants: an explorative study. (2006 Mar 5)Lucht MAm J Med Genet B Neuropsychiatr Genet