Gene info: ID 2560

Gene: GABRB1

GENE ID: 2560

Synonyms: EIEE45

Description: gamma-aminobutyric acid type A receptor beta1 subunit

Gene type: protein-coding

Location: 4p12

dbXrefs: Ensembl:ENSG00000163288 MIM:137190 Vega:OTTHUMG00000044269 UniprotKB:P18505

RefSeq: NG_051831.1

Retrived from: PubMed

SNPs: 0 ANCO-SNPs

Phenotype: ND|AD

# Publications: 14

Sherlock p-value : NA (AD) NA (ND) (Frontal_Cortex)

Pascal p-value : 2.527e-1 (AD) 8.453e-1 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol	Pearson Correlation Coefficient
GPR75	0.807
ADRA1A	0.734
MKLN1	0.728
P2RY1	0.724
SOX5	0.705
TNIK	0.701
PCDHGA4	0.697
OPHN1	0.694
GABRA2	0.692
DOCK7	0.685

Top 10 negatively co-expressed genes

Gene Symbol	Pearson Correlation Coefficient
ARHGAP22	-0.379
CETP	-0.332
NPFF	-0.331
S1PR5	-0.329
CYB5R2	-0.329
RBP7	-0.313
GNG8	-0.311
ZAP70	-0.307
PTPRH	-0.305
FAM178B	-0.303

ID	Drug Name	Drug Type	CAS Num	Status	Role
DB00231	Temazepam	Small Molecule	846-50-4	Approved\|Investigational	Target
DB00431	Lindane	Small Molecule	58-89-9	Approved\|Withdrawn	Target
DB00546	Adinazolam	Small Molecule	37115-32-5	Approved	Target
DB00683	Midazolam	Small Molecule	59467-70-8	Approved\|Illicit	Target
DB00690	Flurazepam	Small Molecule	17617-23-1	Approved\|Illicit\|Investigational	Target
DB00801	Halazepam	Small Molecule	23092-17-3	Approved\|Illicit\|Withdrawn	Target
DB00829	Diazepam	Small Molecule	439-14-5	Approved\|Illicit\|Investigational	Target
DB00842	Oxazepam	Small Molecule	604-75-1	Approved	Target
DB00897	Triazolam	Small Molecule	28911-01-5	Approved\|Investigational	Target
DB00898	Ethanol	Small Molecule	64-17-5	Approved	Target
DB01215	Estazolam	Small Molecule	29975-16-4	Approved\|Illicit	Target
DB01440	Gamma Hydroxybutyric Acid	Small Molecule	591-81-1	Approved\|Illicit\|Investigational	Target
DB01558	Bromazepam	Small Molecule	1812-30-2	Approved\|Illicit\|Investigational	Target
DB01559	Clotiazepam	Small Molecule	33671-46-4	Approved\|Illicit	Target
DB01567	Fludiazepam	Small Molecule	3900-31-0	Approved\|Illicit	Target
DB01587	Ketazolam	Small Molecule	27223-35-4	Approved	Target
DB01588	Prazepam	Small Molecule	2955-38-6	Approved\|Illicit	Target
DB01589	Quazepam	Small Molecule	36735-22-5	Approved\|Illicit	Target
DB01594	Cinolazepam	Small Molecule	75696-02-5	Approved	Target
DB01595	Nitrazepam	Small Molecule	146-22-5	Approved	Target
DB00186	Lorazepam	Small Molecule	846-49-1	Approved	Target
DB00189	Ethchlorvynol	Small Molecule	113-18-8	Approved\|Illicit\|Withdrawn	Target
DB00228	Enflurane	Small Molecule	13838-16-9	Approved\|Investigational	Target
DB00231	Temazepam	Small Molecule	846-50-4	Approved\|Investigational	Target
DB00237	Butabarbital	Small Molecule	125-40-6	Approved\|Illicit	Target
DB00241	Butalbital	Small Molecule	77-26-9	Approved\|Illicit	Target
DB00273	Topiramate	Small Molecule	97240-79-4	Approved	Target
DB00292	Etomidate	Small Molecule	33125-97-2	Approved	Target
DB00306	Talbutal	Small Molecule	115-44-6	Approved\|Illicit	Target
DB00312	Pentobarbital	Small Molecule	76-74-4	Approved\|Investigational	Target
DB00334	Olanzapine	Small Molecule	132539-06-1	Approved\|Investigational	Target
DB00349	Clobazam	Small Molecule	22316-47-8	Approved\|Illicit	Target
DB00371	Meprobamate	Small Molecule	57-53-4	Approved\|Illicit	Target
DB00402	Eszopiclone	Small Molecule	138729-47-2	Approved\|Investigational	Target
DB00404	Alprazolam	Small Molecule	28981-97-7	Approved\|Illicit\|Investigational	Target
DB00463	Metharbital	Small Molecule	50-11-3	Withdrawn	Target
DB00475	Chlordiazepoxide	Small Molecule	58-25-3	Approved\|Illicit\|Investigational	Target
DB00543	Amoxapine	Small Molecule	14028-44-5	Approved	Target
DB00555	Lamotrigine	Small Molecule	84057-84-1	Approved\|Investigational	Target
DB00628	Clorazepate	Small Molecule	23887-31-2	Approved\|Illicit	Target
DB00659	Acamprosate	Small Molecule	77337-76-9	Approved\|Investigational	Target
DB00753	Isoflurane	Small Molecule	26675-46-7	Approved	Target
DB00794	Primidone	Small Molecule	125-33-7	Approved	Target
DB00801	Halazepam	Small Molecule	23092-17-3	Approved\|Illicit\|Withdrawn	Target
DB00818	Propofol	Small Molecule	2078-54-8	Approved\|Investigational	Target
DB00829	Diazepam	Small Molecule	439-14-5	Approved\|Illicit\|Investigational	Target
DB00842	Oxazepam	Small Molecule	604-75-1	Approved	Target
DB00897	Triazolam	Small Molecule	28911-01-5	Approved\|Investigational	Target
DB01028	Methoxyflurane	Small Molecule	76-38-0	Approved\|Investigational	Target
DB01049	Ergoloid mesylate	Small Molecule	8067-24-1	Approved	Target
DB01068	Clonazepam	Small Molecule	1622-61-3	Approved\|Illicit	Target
DB01107	Methyprylon	Small Molecule	125-64-4	Approved\|Illicit\|Withdrawn	Target
DB01159	Halothane	Small Molecule	151-67-7	Approved	Target
DB01189	Desflurane	Small Molecule	57041-67-5	Approved	Target
DB01205	Flumazenil	Small Molecule	78755-81-4	Approved	Target
DB01215	Estazolam	Small Molecule	29975-16-4	Approved\|Illicit	Target
DB01236	Sevoflurane	Small Molecule	28523-86-6	Approved	Target
DB01437	Glutethimide	Small Molecule	77-21-4	Approved\|Illicit	Target
DB01588	Prazepam	Small Molecule	2955-38-6	Approved\|Illicit	Target
DB01589	Quazepam	Small Molecule	36735-22-5	Approved\|Illicit	Target
DB01708	Prasterone	Small Molecule	53-43-0	Approved\|Investigational\|Nutraceutical	Target
DB01956	Taurine	Small Molecule	107-35-7	Approved\|Nutraceutical	Target
DB09118	Stiripentol	Small Molecule	49763-96-4	Approved	Target
DB11582	Thiocolchicoside	Small Molecule	602-41-5	Approved\|Investigational	Target
DB11901	Apalutamide	Small Molecule	956104-40-8	Approved\|Investigational	Target

ID	Drug Name	Action	PubMed
C024566	1,1,1-trichloroethane	"1,1,1-trichloroethane promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein]]"	10825391
C091518	1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane	"1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane binds to [GABRA1 protein binds to GABRB1 protein]"	21111751
C091518	1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane	"1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane binds to [GABRB3 protein binds to GABRB1 protein]"	21111751
C091518	1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane	"gamma-Aminobutyric Acid promotes the reaction [1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane binds to [GABRA1 protein binds to GABRB1 protein]]"	21111751
C038844	1-octen-3-ol	1-octen-3-ol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein]]	14664509
C038844	1-octen-3-ol	1-octen-3-ol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein co-treated with GABRB1 protein]]	16569037
C111118	2',3,3',4',5-pentachloro-4-hydroxybiphenyl	"2',3,3',4',5-pentachloro-4-hydroxybiphenyl results in decreased expression of GABRB1 mRNA"	19114083
C016834	3,5-xylenol	"3,5-xylenol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of GABRB1 protein]"	11676023
C459179	4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide	"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of GABRB1 mRNA"	27188386
C054511	4,5-dimethyl-3-hydroxy-2(5H)-furanone	"4,5-dimethyl-3-hydroxy-2(5H)-furanone promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein]]"	14664509
C516138	(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine	"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of GABRB1 mRNA"	27188386
C534316	7-hydroxy-7-methyl-3-methylene-1-octene	7-hydroxy-7-methyl-3-methylene-1-octene promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein co-treated with GABRB1 protein]]	16569037
D000082	Acetaminophen	[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in decreased expression of GABRB1 mRNA	25607892
D000481	Allantoin	Allantoin inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein]]	14664509
D005680	gamma-Aminobutyric Acid	1-octen-3-ol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein]]	14664509
D005680	gamma-Aminobutyric Acid	1-octen-3-ol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein co-treated with GABRB1 protein]]	16569037
D005680	gamma-Aminobutyric Acid	"3,5-xylenol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of GABRB1 protein]"	11676023
D005680	gamma-Aminobutyric Acid	"4,5-dimethyl-3-hydroxy-2(5H)-furanone promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein]]"	14664509
D005680	gamma-Aminobutyric Acid	7-hydroxy-7-methyl-3-methylene-1-octene promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein co-treated with GABRB1 protein]]	16569037
D005680	gamma-Aminobutyric Acid	Allantoin inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein]]	14664509
D005680	gamma-Aminobutyric Acid	benzothiazole promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein]]	14664509
D005680	gamma-Aminobutyric Acid	bisphenol A inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of GABRB1 protein]	11676023
D005680	gamma-Aminobutyric Acid	butylphen promotes the reaction [gamma-Aminobutyric Acid results in increased activity of GABRB1 protein]	11676023
D005680	gamma-Aminobutyric Acid	catechol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein]]	14664509
D005680	gamma-Aminobutyric Acid	Chlorogenic Acid inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein]]	14664509
D005680	gamma-Aminobutyric Acid	Coffee inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein]]	14664509
D005680	gamma-Aminobutyric Acid	Ethanol analog promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein]]	12926865
D005680	gamma-Aminobutyric Acid	gamma-Aminobutyric Acid results in increased activity of GABRB1 protein	11676023
D005680	gamma-Aminobutyric Acid	geraniol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein co-treated with GABRB1 protein]]	16569037
D005680	gamma-Aminobutyric Acid	Guaiacol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein]]	14664509
D005680	gamma-Aminobutyric Acid	linalool promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein co-treated with GABRB1 protein]]	16569037
D005680	gamma-Aminobutyric Acid	maltol inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein]]	14664509
D005680	gamma-Aminobutyric Acid	Theobromine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein]]	14664509
D005680	gamma-Aminobutyric Acid	Theophylline inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein]]	14664509
D005680	gamma-Aminobutyric Acid	"1,1,1-trichloroethane promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein]]"	10825391
D005680	gamma-Aminobutyric Acid	Chloral Hydrate promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein binds to GABRB1 protein]]	10683198
D005680	gamma-Aminobutyric Acid	Chloralose promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein binds to GABRB1 protein]]	10683198
D005680	gamma-Aminobutyric Acid	Chlorobutanol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein binds to GABRB1 protein]]	10683198
D005680	gamma-Aminobutyric Acid	delta-hexachlorocyclohexane promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein binds to GABRG2 protein alternative form]]	11156579
D005680	gamma-Aminobutyric Acid	Enflurane inhibits the reaction [Trichloroethylene promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein]]]	10825391
D005680	gamma-Aminobutyric Acid	Enflurane promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein binds to GABRB1 protein]]	10683198
D005680	gamma-Aminobutyric Acid	Ether promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein binds to GABRB1 protein]]	10683198
D005680	gamma-Aminobutyric Acid	Etomidate promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 binds to GABRB1 binds to GABRE]]	10049148
D005680	gamma-Aminobutyric Acid	Etomidate promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 binds to GABRB1 binds to GABRG2]]	10049148
D005680	gamma-Aminobutyric Acid	"gamma-Aminobutyric Acid promotes the reaction [1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane binds to [GABRA1 protein binds to GABRB1 protein]]"	21111751
D005680	gamma-Aminobutyric Acid	gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein]	10825391
D005680	gamma-Aminobutyric Acid	gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein binds to GABRG2 protein alternative form]	29038840
D005680	gamma-Aminobutyric Acid	gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein binds to GABRB1 protein]	10683198
D005680	gamma-Aminobutyric Acid	gamma-Aminobutyric Acid results in increased activity of [GABRA4 protein binds to GABRB1 protein binds to GABRG2 protein alternative form]	29038840
D005680	gamma-Aminobutyric Acid	gamma-Aminobutyric Acid results in increased activity of [GABRA6 protein binds to GABRB1 protein binds to GABRG2 protein alternative form]	29038840
D005680	gamma-Aminobutyric Acid	Isoflurane promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein binds to GABRB1 protein]]	10683198
D005680	gamma-Aminobutyric Acid	Lindane inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein binds to GABRG2 protein alternative form]]	11156579
D005680	gamma-Aminobutyric Acid	Methoxyflurane promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein binds to GABRB1 protein]]	10683198
D005680	gamma-Aminobutyric Acid	Pentobarbital promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 binds to GABRB1 binds to GABRE]]	10049148
D005680	gamma-Aminobutyric Acid	Pentobarbital promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 binds to GABRB1 binds to GABRG2]]	10049148
D005680	gamma-Aminobutyric Acid	picrotoxinin inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein binds to GABRG2 protein alternative form]]	29038840
D005680	gamma-Aminobutyric Acid	Propofol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 binds to GABRB1 binds to GABRE]]	10049148
D005680	gamma-Aminobutyric Acid	Propofol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 binds to GABRB1 binds to GABRG2]]	10049148
D005680	gamma-Aminobutyric Acid	sevoflurane promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein binds to GABRB1 protein]]	10683198
D005680	gamma-Aminobutyric Acid	tert-Butyl Alcohol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein binds to GABRB1 protein]]	10683198
D005680	gamma-Aminobutyric Acid	Toluene promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein]]	10825391
D005680	gamma-Aminobutyric Acid	tribromoethanol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein binds to GABRB1 protein]]	10683198
D005680	gamma-Aminobutyric Acid	Trichloroethylene promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein]]	10825391
D005680	gamma-Aminobutyric Acid	Trifluoroethanol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein binds to GABRB1 protein]]	10683198
D005680	gamma-Aminobutyric Acid	Diazepam promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein binds to GABRG2 protein]]	1712603
D005680	gamma-Aminobutyric Acid	Ethanol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein binds to GABRG2 protein]]	1712603
D005680	gamma-Aminobutyric Acid	gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein binds to GABRG2 protein]	1712603
D005680	gamma-Aminobutyric Acid	Pentobarbital promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein binds to GABRG2 protein]]	1712603
D005680	gamma-Aminobutyric Acid	Bicuculline inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein]]	1977069
D005680	gamma-Aminobutyric Acid	Flumazenil promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein]]	1977069
D005680	gamma-Aminobutyric Acid	gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein]	1977069
D005680	gamma-Aminobutyric Acid	gamma-Aminobutyric Acid results in increased activity of [GABRG2 protein binds to GABRA1 protein binds to GABRB1 protein]	2165521
D005680	gamma-Aminobutyric Acid	"methyl 6,7-dimethoxy-4-ethyl-beta-carboline-3-carboxylate promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein]]"	1977069
D005680	gamma-Aminobutyric Acid	Pentobarbital promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein]]	1977069
D000643	Ammonium Chloride	Ammonium Chloride affects the expression of GABRB1 mRNA	16483693
D000726	Androgen Antagonists	[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in decreased expression of GABRB1 mRNA	25607892
D001374	Azacitidine	Azacitidine results in increased expression of GABRB1 mRNA	19194470
D001418	Baclofen	Baclofen results in increased expression of GABRB1 protein	15236866
D015123	7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide	"7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of GABRB1 mRNA"	20382639
C005465	benzothiazole	benzothiazole promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein]]	14664509
D004958	Estradiol	[Estradiol co-treated with Progesterone] results in increased expression of GABRB1 mRNA	19833106
D004958	Estradiol	Estradiol results in increased expression of GABRB1 mRNA	19484750
D001640	Bicuculline	Bicuculline inhibits the reaction [Ethanol analog results in increased activity of [GABRA1 protein co-treated with GABRB1 protein]]	16569037
D001640	Bicuculline	Bicuculline results in decreased activity of [GABRA1 protein binds to GABRB1 binds to GABRG2 protein alternative form]	29038840
D001640	Bicuculline	Bicuculline results in decreased activity of [GABRA6 protein binds to GABRB1 binds to GABRG2 protein alternative form]	29038840
D001640	Bicuculline	Bicuculline inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein]]	1977069
C006780	bisphenol A	bisphenol A inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of GABRB1 protein]	11676023
C006780	bisphenol A	bisphenol A results in decreased expression of GABRB1 mRNA	29275510
C006780	bisphenol A	[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in decreased expression of GABRB1 mRNA	25607892
C006780	bisphenol A	bisphenol A results in decreased expression of GABRB1 mRNA	25181051
C006780	bisphenol A	bisphenol A results in increased expression of GABRB1 mRNA	29097150
C006780	bisphenol A	bisphenol A results in increased methylation of GABRB1 gene	28505145
C038091	butylparaben	[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in decreased expression of GABRB1 mRNA	25607892
C006862	butylphen	butylphen promotes the reaction [gamma-Aminobutyric Acid results in increased activity of GABRB1 protein]	11676023
D002251	Carbon Tetrachloride	Carbon Tetrachloride results in decreased expression of GABRB1 mRNA	16644059
C034221	catechol	catechol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein]]	14664509
D002697	Chloral Hydrate	Chloral Hydrate promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein binds to GABRB1 protein]]	10683198
D002698	Chloralose	Chloralose promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein binds to GABRB1 protein]]	10683198
D002698	Chloralose	Chloralose results in increased activity of [GABRA2 protein binds to GABRB1 protein]	10683198
D002698	Chloralose	Chloralose results in increased activity of [GABRA2 protein binds to GABRB1 protein mutant form]	10683198
D002698	Chloralose	Chloralose results in increased activity of [GABRA2 protein mutant form binds to GABRB1 protein]	10683198
D002698	Chloralose	Picrotoxin inhibits the reaction [Chloralose results in increased activity of [GABRA2 protein binds to GABRB1 protein]]	10683198
D002724	Chlorobutanol	Chlorobutanol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein binds to GABRB1 protein]]	10683198
D002726	Chlorogenic Acid	Chlorogenic Acid inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein]]	14664509
D003042	Cocaine	Cocaine results in increased expression of GABRB1 mRNA	17898221
D003069	Coffee	Coffee inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein]]	14664509
C086916	delta-hexachlorocyclohexane	delta-hexachlorocyclohexane promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein binds to GABRG2 protein alternative form]]	11156579
C086916	delta-hexachlorocyclohexane	delta-hexachlorocyclohexane results in decreased activity of [GABRA1 protein binds to GABRB1 protein binds to GABRG2 protein alternative form]	11156579
D003975	Diazepam	Diazepam results in increased activity of [GABRA1 protein binds to GABRB1 binds to GABRG2 protein alternative form]	29038840
D003975	Diazepam	Diazepam promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein binds to GABRG2 protein]]	1712603
D003975	Diazepam	Diazepam results in increased expression of GABRB1 mRNA	11804615
D003993	Dibutyl Phthalate	[Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of GABRB1 mRNA	25607892
D003633	Dichlorodiphenyl Dichloroethylene	[Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of GABRB1 mRNA	25607892
D004041	Dietary Fats	Dietary Fats results in increased expression of GABRB1 mRNA	25016146
D004051	Diethylhexyl Phthalate	[Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of GABRB1 mRNA	25607892
D004052	Diethylnitrosamine	Diethylnitrosamine results in decreased expression of GABRB1 mRNA	12807726
D004726	Endosulfan	Endosulfan binds to GABRB1 protein	11489356
D004737	Enflurane	Enflurane inhibits the reaction [Trichloroethylene promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein]]]	10825391
D004737	Enflurane	Enflurane promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein binds to GABRB1 protein]]	10683198
C118739	entinostat	entinostat results in increased expression of GABRB1 mRNA	27188386
C038939	enzacamene	[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in decreased expression of GABRB1 mRNA	25607892
C109476	epoxiconazole	[Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of GABRB1 mRNA	25607892
D000431	Ethanol	Bicuculline inhibits the reaction [Ethanol analog results in increased activity of [GABRA1 protein co-treated with GABRB1 protein]]	16569037
D000431	Ethanol	Ethanol analog promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein]]	12926865
D000431	Ethanol	Ethanol analog results in increased activity of [GABRA1 protein co-treated with GABRB1 protein]	16569037
D000431	Ethanol	Ethanol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein binds to GABRG2 protein]]	1712603
D004986	Ether	Ether promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein binds to GABRB1 protein]]	10683198
D004997	Ethinyl Estradiol	Ethinyl Estradiol results in increased expression of GABRB1 mRNA	29097150
D005045	Etomidate	Etomidate promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 binds to GABRB1 binds to GABRE]]	10049148
D005045	Etomidate	Etomidate promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 binds to GABRB1 binds to GABRG2]]	10049148
C047360	felbamate	felbamate results in decreased activity of [GABRA1 protein binds to GABRB1 protein]	17056029
C047360	felbamate	felbamate results in decreased activity of [GABRA4 protein binds to GABRB1 protein binds to GABRG2 protein alternative form]	17056029
C047360	felbamate	felbamate results in decreased activity of [GABRA6 protein binds to GABRB1 protein binds to GABRG2 protein alternative form]	17056029
C082360	fipronil	fipronil binds to GABRB1 protein	11489356
C082360	fipronil	fipronil results in decreased activity of [GABRA1 protein binds to GABRB1 binds to GABRG2 protein alternative form]	29038840
C082360	fipronil	fipronil results in decreased activity of [GABRA6 protein binds to GABRB1 binds to GABRG2 protein alternative form]	29038840
D005442	Flumazenil	Flumazenil promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein]]	1977069
D005481	Flurothyl	Flurothyl results in decreased activity of [GABRA1 protein binds to GABRB1 protein binds to GABRG2 protein]	11090101
C007836	geraniol	geraniol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein co-treated with GABRB1 protein]]	16569037
D006139	Guaiacol	Guaiacol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein]]	14664509
D017313	Fenretinide	Fenretinide results in increased expression of GABRB1 mRNA	28973697
D007530	Isoflurane	Isoflurane promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein binds to GABRB1 protein]]	10683198
D007608	Kainic Acid	Kainic Acid results in increased expression of GABRB1 mRNA	27386150
D007608	Kainic Acid	Quercetin inhibits the reaction [Kainic Acid results in increased expression of GABRB1 mRNA]	27386150
D007854	Lead	Lead affects the expression of GABRB1 mRNA	28903495
C018584	linalool	linalool promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein co-treated with GABRB1 protein]]	16569037
D001556	Lindane	Lindane binds to GABRB1 protein	11489356
D001556	Lindane	Lindane inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein binds to GABRG2 protein alternative form]]	11156579
D008044	Linuron	[Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of GABRB1 mRNA	25607892
C008316	maltol	maltol inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein]]	14664509
D008733	Methoxyflurane	Methoxyflurane promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein binds to GABRB1 protein]]	10683198
C034818	methyl 6,7-dimethoxy-4-ethyl-beta-carboline-3-carboxylate	"methyl 6,7-dimethoxy-4-ethyl-beta-carboline-3-carboxylate promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein]]"	1977069
D009118	Muscimol	Muscimol binds to GABRB1 protein	9661255
C118580	octylmethoxycinnamate	[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in decreased expression of GABRB1 mRNA	25607892
D010269	Paraquat	Paraquat results in decreased expression of GABRB1 mRNA	18198484
D010424	Pentobarbital	Pentobarbital promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 binds to GABRB1 binds to GABRE]]	10049148
D010424	Pentobarbital	Pentobarbital promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 binds to GABRB1 binds to GABRG2]]	10049148
D010424	Pentobarbital	Pentobarbital results in increased activity of [GABRA1 binds to GABRB1 binds to GABRE]	10049148
D010424	Pentobarbital	Pentobarbital results in increased activity of [GABRA1 binds to GABRB1 binds to GABRG2]	10049148
D010424	Pentobarbital	Pentobarbital promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein binds to GABRG2 protein]]	1712603
D010424	Pentobarbital	Pentobarbital promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein]]	1977069
D010424	Pentobarbital	Pentobarbital results in increased activity of [GABRG2 protein binds to GABRA1 protein binds to GABRB1 protein]	2165521
D010424	Pentobarbital	Pentobarbital results in increased expression of GABRB1 mRNA	9661255
C052329	phaclofen	phaclofen results in decreased expression of GABRB1 protein	15236866
D010852	Picrotoxin	Picrotoxin inhibits the reaction [Chloralose results in increased activity of [GABRA2 protein binds to GABRB1 protein]]	10683198
C022961	picrotoxinin	picrotoxinin inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein binds to GABRG2 protein alternative form]]	29038840
D011280	Pregnanolone	Pregnanolone results in increased activity of [GABRA1 protein binds to GABRB1 binds to GABRG2 protein alternative form]	29038840
C045362	prochloraz	[Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of GABRB1 mRNA	25607892
C035988	procymidone	[Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of GABRB1 mRNA	25607892
D011374	Progesterone	[Estradiol co-treated with Progesterone] results in increased expression of GABRB1 mRNA	19833106
D011374	Progesterone	Progesterone results in decreased expression of GABRB1 mRNA	19690047
D011374	Progesterone	Progesterone affects the expression of GABRB1 protein	15834956
D015742	Propofol	Propofol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 binds to GABRB1 binds to GABRE]]	10049148
D015742	Propofol	Propofol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 binds to GABRB1 binds to GABRG2]]	10049148
D015742	Propofol	Propofol results in increased activity of [GABRA1 protein binds to GABRB1 binds to GABRG2 protein alternative form]	29038840
D011441	Propylthiouracil	Propylthiouracil results in increased expression of GABRB1 mRNA	24780913
D011794	Quercetin	Quercetin inhibits the reaction [Kainic Acid results in increased expression of GABRB1 mRNA]	27386150
C009250	sevoflurane	sevoflurane promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein binds to GABRB1 protein]]	10683198
C017947	sodium arsenite	sodium arsenite affects the methylation of GABRB1 gene	28589171
D020002	tert-Butyl Alcohol	tert-Butyl Alcohol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein binds to GABRB1 protein]]	10683198
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin affects the expression of GABRB1 mRNA	21570461
D013805	Theobromine	Theobromine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein]]	14664509
D013806	Theophylline	Theophylline inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein]]	14664509
D014050	Toluene	Toluene promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein]]	10825391
D014212	Tretinoin	Tretinoin results in increased expression of GABRB1 mRNA	21934132
C062527	tribromoethanol	tribromoethanol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein binds to GABRB1 protein]]	10683198
D014241	Trichloroethylene	Enflurane inhibits the reaction [Trichloroethylene promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein]]]	10825391
D014241	Trichloroethylene	Trichloroethylene promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein]]	10825391
D014270	Trifluoroethanol	Trifluoroethanol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein binds to GABRB1 protein]]	10683198
D014635	Valproic Acid	"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of GABRB1 mRNA"	27188386
D014635	Valproic Acid	Valproic Acid affects the expression of GABRB1 mRNA	25979313
D014635	Valproic Acid	Valproic Acid results in increased expression of GABRB1 mRNA	23179753\|2438349
D000069470	Venlafaxine Hydrochloride	Venlafaxine Hydrochloride results in increased expression of GABRB1 mRNA	25423262
C025643	vinclozolin	[Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of GABRB1 mRNA	25607892
C085665	zaleplon	zaleplon deficiency results in increased expression of GABRB1 mRNA	11804615
C049109	zolpidem	zolpidem deficiency results in increased expression of GABRB1 mRNA	11804615

GO/Pathway

GO ID	GO Term	Qualifier	Evidence	PubMed
GO:0004890	GABA-A receptor activity	CONTRIBUTES_TO	IBA	21873635
GO:0004890	GABA-A receptor activity	-	ISS	-
GO:0005230	extracellular ligand-gated ion channel activity	CONTRIBUTES_TO	IBA	21873635
GO:0015276	ligand-gated ion channel activity	-	ISS	-
GO:0022851	GABA-gated chloride ion channel activity	-	IDA	9039914
GO:0022851	GABA-gated chloride ion channel activity	-	IMP	26950270
GO:0050811	GABA receptor binding	-	IEA	-

GO ID	GO Term	Qualifier	Evidence	PubMed
GO:0006811	ion transport	-	ISS	-
GO:0007165	signal transduction	-	IBA	21873635
GO:0007165	signal transduction	-	TAS	2465923
GO:0007214	gamma-aminobutyric acid signaling pathway	-	IMP	26950270
GO:0007268	chemical synaptic transmission	-	IBA	21873635
GO:0009636	response to toxic substance	-	IEA	-
GO:0021954	central nervous system neuron development	-	IEA	-
GO:0032570	response to progesterone	-	IEA	-
GO:0034220	ion transmembrane transport	-	IBA	21873635
GO:0042391	regulation of membrane potential	-	IBA	21873635
GO:0042698	ovulation cycle	-	IEA	-
GO:0050877	nervous system process	-	IBA	21873635
GO:0071420	cellular response to histamine	-	ISS	-
GO:1902476	chloride transmembrane transport	-	IDA	9039914

GO ID	GO Term	Qualifier	Evidence	PubMed
GO:0005635	nuclear envelope	-	IEA	-
GO:0005737	cytoplasm	-	IEA	-
GO:0005886	plasma membrane	-	IDA	26950270
GO:0005886	plasma membrane	-	TAS	-
GO:0005887	integral component of plasma membrane	-	IBA	21873635
GO:0005887	integral component of plasma membrane	-	ISS	-
GO:0030054	cell junction	-	IEA	-
GO:0030425	dendrite	-	IEA	-
GO:0034707	chloride channel complex	-	IEA	-
GO:0043005	neuron projection	-	IBA	21873635
GO:0045202	synapse	-	IBA	21873635
GO:0045211	postsynaptic membrane	-	IEA	-
GO:1902711	GABA-A receptor complex	-	IBA	21873635
GO:1902711	GABA-A receptor complex	-	IDA	9039914 26950270
GO:1902711	GABA-A receptor complex	-	ISS	-

KEGG ID	KEGG Term
hsa04080	Neuroactive ligand-receptor interaction

Reactome ID	Reactome Term	Evidence
R-HSA-112314	Neurotransmitter receptors and postsynaptic signal transmission	TAS
R-HSA-112314	Neurotransmitter receptors and postsynaptic signal transmission	IEA
R-HSA-112315	Transmission across Chemical Synapses	TAS
R-HSA-112315	Transmission across Chemical Synapses	IEA
R-HSA-112316	Neuronal System	TAS
R-HSA-112316	Neuronal System	IEA
R-HSA-977441	GABA A receptor activation	TAS
R-HSA-977443	GABA receptor activation	TAS

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID	Title (Year)	Author	Journal
15024690	Variations in GABRA2, encoding the alpha 2 subunit of the GABA(A) receptor, are associated with alcohol dependence and with brain oscillations. (2004 Apr)	Edenberg HJ	Am J Hum Genet
16451603	Analysis of alcohol dependence phenotype in the COGA families using covariates to detect linkage. (2005 Dec 30)	Reck BH	BMC Genet
12555233	Association of GABA(A) receptors and alcohol dependence and the effects of genetic imprinting. (2003 Feb)	Song J	Am J Med Genet B Neuropsychiatr Genet
24281383	Mutations in the Gabrb1 gene promote alcohol consumption through increased tonic inhibition. (2013)	Anstee QM	Nat Commun
21143246	Neurotransmitter and neuromodulator genes associated with a history of depressive symptoms in individuals with alcohol dependence. (2011 Mar)	Kertes DA	Alcohol Clin Exp Res
10597473	Genome search for alcohol dependence using the weighted pairwise correlation linkage method: interesting findings on chromosome 4. (1999)	Zinn-Justin A	Genet Epidemiol
16451575	Multivariate linkage analysis using the electrophysiological phenotypes in the COGA alcoholism data. (2005 Dec 30)	Zhang H	BMC Genet
22354695	Autosomal linkage scan for loci predisposing to comorbid dependence on multiple substances. (2012 Jun)	Yang BZ	Am J Med Genet B Neuropsychiatr Genet
26250693	GABRA2 Alcohol Dependence Risk Allele is Associated with Reduced Expression of Chromosome 4p12 GABAA Subunit Genes in Human Neural Cultures. (2015 Sep)	Lieberman R	Alcohol Clin Exp Res
10490712	Human chromosomes 11p15 and 4p12 and alcohol dependence: possible association with the GABRB1 gene. (1999 Oct 15)	Parsian A	Am J Med Genet
16451566	Comparison of marker types and map assumptions using Markov chain Monte Carlo-based linkage analysis of COGA data. (2005 Dec 30)	Sieh W	BMC Genet
28416970	DNA methylation profiling in peripheral lung tissues of smokers and patients with COPD. (2017)	Sundar IK	Clin Epigenetics
10597459	Whole genome association studies for genes affecting alcohol dependence. (1999)	Sun F	Genet Epidemiol
28261068	GABRB1 Single Nucleotide Polymorphism Associated with Altered Brain Responses (but not Performance) during Measures of Impulsivity and Reward Sensitivity in Human Adolescents. (2017)	Duka T	Front Behav Neurosci