Gene: ANKRD31

256006
-
ankyrin repeat domain 31
protein-coding
5q13.3
Ensembl:ENSG00000145700 Vega:OTTHUMG00000162649 UniprotKB:Q8N7Z5
NG_053151.1
SNP Mapped
3   ANCO-SNPs
CD
0   
NA (AD)  NA (ND)   (Frontal_Cortex)
8.887e-1 (AD)  1.572e-1 (ND)

ANCO-SNPs

SNP ID Position Alleles Trait Variation Type
rs10054860chr5:75150979 (GRCh38.p7)T>Gcocaine dependenceSNV(Single Nucleotide Variation)
rs961098chr5:75104561 (GRCh38.p7)G>A / G>Ccocaine dependenceSNV(Single Nucleotide Variation)
rs4626318chr5:75069932 (GRCh38.p7)A>Ccocaine dependenceSNV(Single Nucleotide Variation)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
MSH30.585
FKTN0.575
ORC30.567
DENND1B0.563
LTN10.562
MTR0.56
TBC1D310.56
CEP1920.559
PMS10.559
TMEM2600.556

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
ATP6V0A4-0.295
NKX6-1-0.271
HRASLS2-0.253
EN1-0.23
HMX1-0.225
C1QL2-0.221
S100A14-0.219
PGF-0.211
CCDC102A-0.21
FOXD1-0.207

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C006780bisphenol Abisphenol A results in decreased expression of ANKRD31 mRNA25181051
D016572CyclosporineCyclosporine results in decreased methylation of ANKRD31 promoter27989131

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO ID GO Term Qualifier Evidence PubMed
GO ID GO Term Qualifier Evidence PubMed
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal