Gene: ABI3BP

25890
NESHBP|TARSH
ABI family member 3 binding protein
protein-coding
3q12.2
Ensembl:ENSG00000154175 MIM:606279 Vega:OTTHUMG00000159094 UniprotKB:Q7Z7G0
NC_000003.12
SNP Mapped
1   ANCO-SNPs
AD
0   
NA (AD)  NA (ND)   (Frontal_Cortex)
9.768e-1 (AD)  2.029e-1 (ND)

ANCO-SNPs

SNP ID Position Alleles Trait Variation Type
rs12632235chr3:100817440 (GRCh38.p7)C>Talcohol dependenceSNV(Single Nucleotide Variation)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
SERPIND10.749
INSRR0.733
ANGPT10.714
NPNT0.662
CDK150.656
SLC22A20.653
SLC22A80.645
MYO3A0.635
JPH20.633
SLC13A40.632

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
SOHLH1-0.343
TNNT2-0.318
NANOS3-0.315
NEUROD2-0.305
YBX2-0.305
EMX1-0.284
TRIM54-0.274
TEX29-0.269
KRTAP5-8-0.264
BAIAP2L2-0.256

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C0264861,2,5,6-dibenzanthracene"1,2,5,6-dibenzanthracene results in decreased expression of ABI3BP mRNA"26377693
D001280AtrazineAtrazine results in decreased expression of ABI3BP mRNA25929836
C547126AZM551248AZM551248 results in increased expression of ABI3BP mRNA22323515
C030935benz(a)anthracene[Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of ABI3BP mRNA27858113
C006703benzo(b)fluoranthene[Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of ABI3BP mRNA27858113
D001564Benzo(a)pyreneBenzo(a)pyrene results in decreased expression of ABI3BP mRNA20106945
D001564Benzo(a)pyrene[Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of ABI3BP mRNA27858113
D001564Benzo(a)pyreneBenzo(a)pyrene results in decreased expression of ABI3BP mRNA20713471|2156981
D001564Benzo(a)pyreneBenzo(a)pyrene results in decreased expression of ABI3BP mRNA21839799
D004958EstradiolEstradiol results in decreased expression of ABI3BP mRNA19484750
D001622BetaineBetaine results in increased expression of ABI3BP mRNA26391144
C006780bisphenol Abisphenol A results in increased expression of ABI3BP mRNA27685785
C006780bisphenol Abisphenol A results in decreased expression of ABI3BP mRNA25181051
C018475butyraldehydebutyraldehyde results in decreased expression of ABI3BP mRNA26079696
D002251Carbon TetrachlorideCarbon Tetrachloride results in decreased expression of ABI3BP mRNA17484886
D004390ChlorpyrifosChlorpyrifos results in increased expression of ABI3BP mRNA21356183
D002857ChromiumChromium results in decreased expression of ABI3BP mRNA21437242
C031180chrysene[Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of ABI3BP mRNA27858113
C031180chrysenechrysene results in increased expression of ABI3BP mRNA26377693
D016572CyclosporineCyclosporine results in decreased expression of ABI3BP mRNA20106945
D003907Dexamethasone[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin] results in decreased expression of ABI3BP mRNA28628672
D003993Dibutyl PhthalateDibutyl Phthalate results in decreased expression of ABI3BP mRNA21266533
D004041Dietary FatsDietary Fats results in increased expression of ABI3BP mRNA25016146
D004052Diethylnitrosamine[Diethylnitrosamine co-treated with Phenobarbital] results in decreased expression of ABI3BP mRNA24535843
D004052DiethylnitrosamineDiethylnitrosamine results in increased expression of ABI3BP mRNA24535843
D002117CalcitriolCalcitriol results in decreased expression of ABI3BP mRNA26485663
D0198131,2-Dimethylhydrazine"[APC protein affects the susceptibility to 1,2-Dimethylhydrazine] which results in decreased expression of ABI3BP mRNA"27840820
D004237DiuronDiuron results in decreased expression of ABI3BP mRNA25152437
D004237DiuronDiuron results in increased expression of ABI3BP mRNA21551480
D004726EndosulfanEndosulfan inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of ABI3BP mRNA]26159488
D000431EthanolEthanol results in decreased expression of ABI3BP mRNA29018328
D011345FenofibrateFenofibrate results in decreased expression of ABI3BP mRNA25572481
D005557FormaldehydeFormaldehyde results in increased expression of ABI3BP mRNA23649840|2893796
C412815GW 4064GW 4064 results in decreased expression of ABI3BP mRNA26655953
D017313FenretinideFenretinide results in decreased expression of ABI3BP mRNA28973697
D007213Indomethacin[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin] results in decreased expression of ABI3BP mRNA28628672
D0150561-Methyl-3-isobutylxanthine[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin] results in decreased expression of ABI3BP mRNA28628672
D008748MethylcholanthreneMethylcholanthrene results in decreased expression of ABI3BP mRNA20713471
D018817N-Methyl-3,4-methylenedioxyamphetamine"N-Methyl-3,4-methylenedioxyamphetamine results in decreased expression of ABI3BP mRNA"26251327
D037742Nanotubes, Carbon"Nanotubes, Carbon analog results in decreased expression of ABI3BP mRNA"25554681
D037742Nanotubes, Carbon"Nanotubes, Carbon results in decreased expression of ABI3BP mRNA"25554681
C029938nickel sulfatenickel sulfate results in increased expression of ABI3BP mRNA22714537
C572573N-nitroso-tris-chloroethylurea[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ABI3BP mRNA27935865
C030110oxaliplatin[oxaliplatin co-treated with Topotecan] results in increased expression of ABI3BP mRNA25729387
C030110oxaliplatinoxaliplatin results in increased expression of ABI3BP mRNA25729387
D010634Phenobarbital[Diethylnitrosamine co-treated with Phenobarbital] results in decreased expression of ABI3BP mRNA24535843
D010634PhenobarbitalPhenobarbital affects the expression of ABI3BP mRNA19136022|2309116
C060836pioglitazone[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ABI3BP mRNA27935865
C006253pirinixic acidpirinixic acid affects the expression of ABI3BP mRNA19136022
C006253pirinixic acidpirinixic acid results in decreased expression of ABI3BP mRNA20813756
D010936Plant ExtractsPlant Extracts results in decreased expression of ABI3BP mRNA23557933
C027373potassium chromate(VI)potassium chromate(VI) results in decreased expression of ABI3BP mRNA22714537
D011374ProgesteroneProgesterone results in decreased expression of ABI3BP mRNA23012394
D011374ProgesteroneProgesterone results in increased expression of ABI3BP mRNA20864642
D053260SootSoot results in decreased expression of ABI3BP mRNA26551751
D013749TetrachlorodibenzodioxinEndosulfan inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of ABI3BP mRNA]26159488
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased expression of ABI3BP mRNA20106945|2615948
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of ABI3BP mRNA21570461
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased expression of ABI3BP mRNA26290441
D019772Topotecan[oxaliplatin co-treated with Topotecan] results in increased expression of ABI3BP mRNA25729387
D019772TopotecanTopotecan results in increased expression of ABI3BP mRNA25729387
C032910triadimefontriadimefon results in decreased expression of ABI3BP mRNA26705709
C012589trichostatin Atrichostatin A results in decreased expression of ABI3BP mRNA24935251
C012589trichostatin Atrichostatin A results in increased expression of ABI3BP mRNA26705709
C016805tris(1,3-dichloro-2-propyl)phosphate"tris(1,3-dichloro-2-propyl)phosphate results in decreased expression of ABI3BP mRNA"24407104
D014635Valproic AcidValproic Acid results in decreased expression of ABI3BP mRNA24935251
D014635Valproic AcidValproic Acid affects the expression of ABI3BP mRNA17963808
D014638VanadatesVanadates results in increased expression of ABI3BP mRNA22714537
D001335Vehicle EmissionsVehicle Emissions results in decreased methylation of ABI3BP gene25560391
C025643vinclozolinvinclozolin affects the expression of ABI3BP mRNA19015723
C025643vinclozolinvinclozolin results in decreased expression of ABI3BP mRNA23034163
C088658zoledronic acidzoledronic acid results in decreased expression of ABI3BP mRNA24714768

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0005518collagen binding-IEA-  
GO:0008201heparin binding-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO:0010811positive regulation of cell-substrate adhesion-IEA-  
GO:0030198extracellular matrix organization-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO:0005576extracellular region-HDA27068509  
GO:0005614interstitial matrix-IEA-  
GO:0005615extracellular space-HDA20551380  
GO:0062023collagen-containing extracellular matrix-HDA27559042  
GO:0062023collagen-containing extracellular matrixcolocalizes_withHDA20551380  
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal