Gene: GAPDH

2597
G3PD|GAPD|HEL-S-162eP
glyceraldehyde-3-phosphate dehydrogenase
protein-coding
12p13.31
Ensembl:ENSG00000111640 MIM:138400 Vega:OTTHUMG00000137379 UniprotKB:P04406
NG_007073.2
PubMed
CD|ND|AD
30   
NA (AD)  NA (ND)   (Frontal_Cortex)
5.499e-2 (AD)  1.124e-1 (ND)

DNA Methylation

Probe Locus(GRCh37) Gene Region p-val Trait PubMed ID
cg26826729chr12:6646450GAPDHGene body1.737e-4Alcohol use disorders26763658

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
PEBP10.962
RAB7A0.962
CHMP4B0.961
CFL10.958
OAZ10.958
COPS60.957
PSMB40.956
MRFAP10.956
ARF10.954
ACTB0.953

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
OR4F5-0.928
OR4F29-0.915
MTRNR2L6-0.178
MTRNR2L9-0.166
KLRB1-0.162
C8orf74-0.151
KCNJ15-0.148
HMHB1-0.147
MTRNR2L10-0.145
FCRL1-0.141

Drugs/Compounds

ID Drug Name Drug Type CAS Num Status Role
DB00157NADHSmall Molecule58-68-4Approved|NutraceuticalTarget
DB02059Adenosine-5-DiphosphoriboseSmall Molecule-ExperimentalTarget
DB03893Thionicotinamide-Adenine-DinucleotideSmall MoleculeExperimentalTarget
DB073474-(2-Aminoethyl)Benzenesulfonyl FluorideSmall Molecule34284-75-8ExperimentalTarget
DB09092XanthinolSmall Molecule2530-97-4Approved|WithdrawnTarget
DB09130CopperSmall Molecule7440-50-8Approved|InvestigationalTarget
DB11638ArtenimolSmall Molecule71939-50-9Approved|InvestigationalTarget
DB11638ArtenimolSmall Molecule71939-50-9Approved|InvestigationalTarget
ID Drug Name Action PubMed
C0252051,10-phenanthroline"1,10-phenanthroline results in increased expression of GAPDH mRNA"19502547
D0140131,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt"1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt binds to GAPDH protein"24059224
C0493251,2-dithiol-3-thione"1,2-dithiol-3-thione results in increased expression of GAPDH mRNA"19162173
C0407561,2-naphthoquinone"1,2-naphthoquinone binds to GAPDH protein"21827172
C0407561,2-naphthoquinone"1,2-naphthoquinone results in decreased activity of GAPDH protein"21827172
C0407561,2-naphthoquinone"[Buthionine Sulfoximine results in decreased abundance of Glutathione] promotes the reaction [1,2-naphthoquinone binds to GAPDH protein]"21827172
C0407561,2-naphthoquinone"[Buthionine Sulfoximine results in decreased abundance of Glutathione] promotes the reaction [1,2-naphthoquinone results in decreased activity of GAPDH protein]"21827172
C0297902,2',3',4,4',5-hexachlorobiphenyl"2,2',3',4,4',5-hexachlorobiphenyl results in decreased expression of GAPDH protein"21673325
C5112952,2',4,4'-tetrabromodiphenyl ether"2,2',4,4'-tetrabromodiphenyl ether results in increased expression of GAPDH mRNA"18084045
C0164032,4-dinitrotoluene"2,4-dinitrotoluene affects the expression of GAPDH mRNA"16917068
C0164032,4-dinitrotoluene"2,4-dinitrotoluene results in decreased expression of GAPDH mRNA"16917068
C0158022,6-dichloro-4-nitrophenol"2,6-dichloro-4-nitrophenol results in increased expression of GAPDH mRNA"11227219
C0235142,6-dinitrotoluene"2,6-dinitrotoluene affects the expression of GAPDH mRNA"21346803
C0227762-bromopalmitate2-bromopalmitate results in increased activity of GAPDH protein10650946
C0546493-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol"3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol results in decreased expression of GAPDH mRNA"12734338
C0284513,4,3',4'-tetrachlorobiphenyl"3,4,3',4'-tetrachlorobiphenyl results in decreased activity of GAPDH protein"15556062
C0230353,4,5,3',4'-pentachlorobiphenyl"3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of GAPDH mRNA"28973690
C0074303,4-dihydroxyphenylacetaldehyde"3,4-dihydroxyphenylacetaldehyde binds to and affects the metabolism of GAPDH protein"19537779
C0074303,4-dihydroxyphenylacetaldehyde"Ascorbic Acid affects the reaction [3,4-dihydroxyphenylacetaldehyde binds to and affects the metabolism of GAPDH protein]"19537779
C0074303,4-dihydroxyphenylacetaldehyde"sodium cyanoborohydride affects the reaction [3,4-dihydroxyphenylacetaldehyde binds to and affects the metabolism of GAPDH protein]"19537779
C0579203-buten-2-one3-buten-2-one binds to and results in decreased activity of GAPDH protein22084934
C0179063-dinitrobenzene3-dinitrobenzene results in increased oxidation of GAPDH protein25716674
C0153923-nitropropionic acid3-nitropropionic acid results in increased expression of GAPDH mRNA21827809
C0153923-nitropropionic acidGinkgo biloba extract inhibits the reaction [3-nitropropionic acid results in increased expression of GAPDH mRNA]21827809
C4902573-O-caffeoyl-1-methylquinic acid3-O-caffeoyl-1-methylquinic acid results in increased expression of GAPDH mRNA14732289
C0051563-phosphoglycerate[GAPDH protein co-treated with 3-phosphoglycerate co-treated with NAD] results in increased chemical synthesis of sodium arsenite15788719
C0051563-phosphoglycerate[GAPDH protein co-treated with 3-phosphoglycerate co-treated with NAD] results in increased reduction of sodium arsenate analog15788719
C0051563-phosphoglycerateheptelidic acid inhibits the reaction [[GAPDH protein co-treated with 3-phosphoglycerate co-treated with NAD] results in increased reduction of sodium arsenate analog]15788719
C0352074-amino-2,6-dinitrotoluene"4-amino-2,6-dinitrotoluene affects the expression of GAPDH mRNA"21346803
C0326424-aminophenylarsenoxide4-aminophenylarsenoxide binds to GAPDH protein26598702
C0326424-aminophenylarsenoxidearsenic trioxide inhibits the reaction [4-aminophenylarsenoxide binds to GAPDH protein]26598702
C0275764-hydroxy-2-nonenalHydroxyurea promotes the reaction [4-hydroxy-2-nonenal binds to GAPDH protein]20889679
C0275764-hydroxy-2-nonenal[Hydroxyurea promotes the reaction [4-hydroxy-2-nonenal binds to GAPDH protein]] which results in decreased activity of GAPDH protein20889679
C0275764-hydroxy-2-nonenal[Hydroxyurea results in increased abundance of Free Radicals] promotes the reaction [4-hydroxy-2-nonenal binds to GAPDH protein]23696560
C1052604-tert-octylphenol4-tert-octylphenol results in increased expression of GAPDH mRNA10822019
C0801227-nitroindazole[7-nitroindazole results in decreased chemical synthesis of Nitric Oxide] inhibits the reaction [Paraquat affects the localization of GAPDH protein]20478973
D000079Acetaldehyde[MPO protein co-treated with XDH protein co-treated with Acetaldehyde co-treated with Serotonin] affects the metabolism of and binds to GAPDH protein23009681
D000082AcetaminophenAcetaminophen affects the expression of GAPDH mRNA25064622
D000082AcetaminophenAcetaminophen results in increased expression of GAPDH mRNA22563491
D000082AcetaminophenAcetaminophen results in increased expression of GAPDH protein15800402
D019342Acetic AcidAcetic Acid results in increased expression of GAPDH protein21296659
D000111AcetylcysteineAcetylcysteine inhibits the reaction [arsenite results in decreased expression of GAPDH protein]15175009
D000111AcetylcysteineAcetylcysteine results in decreased expression of GAPDH mRNA11108245
C011632acetyl phosphate[GAPDH protein co-treated with acetyl phosphate co-treated with NAD co-treated with Dithiothreitol] results in increased reduction of sodium arsenate analog19474219
C011632acetyl phosphate[GAPDH protein co-treated with acetyl phosphate co-treated with NAD co-treated with Glutathione] results in increased reduction of sodium arsenate analog19474219
C011632acetyl phosphate[GAPDH protein co-treated with acetyl phosphate co-treated with NAD co-treated with Mercaptoethanol] results in increased reduction of sodium arsenate analog19474219
C011632acetyl phosphate[GAPDH protein co-treated with acetyl phosphate co-treated with NAD co-treated with Succimer] results in increased reduction of sodium arsenate analog19474219
C011632acetyl phosphate[GAPDH protein co-treated with acetyl phosphate co-treated with NAD co-treated with Unithiol] results in increased reduction of sodium arsenate analog19474219
C011632acetyl phosphateheptelidic acid inhibits the reaction [[GAPDH protein co-treated with acetyl phosphate co-treated with NAD co-treated with Glutathione] results in increased reduction of sodium arsenate analog]19474219
D000171Acrolein[Acrolein affects the metabolism of ALB protein] which results in decreased activity of GAPDH protein12032148
D000171Acrolein[Acrolein affects the metabolism of ALB protein] which results in decreased sulfation of GAPDH protein12032148
D000171AcroleinGlutathione inhibits the reaction [[Acrolein affects the metabolism of ALB protein] which results in decreased activity of GAPDH protein]12032148
D000171AcroleinAcrolein binds to and results in decreased activity of GAPDH protein22084934
D000171AcroleinAcrolein binds to GAPDH protein17023561
D020106AcrylamideAcrylamide binds to and results in decreased activity of GAPDH protein22084934
D020106AcrylamideAcrylamide results in decreased expression of GAPDH mRNA28959563
D000244Adenosine DiphosphateAdenosine Diphosphate inhibits the reaction [[GAPDH protein co-treated with NAD co-treated with Glyceraldehyde 3-Phosphate co-treated with Glutathione] results in increased reduction of sodium arsenite analog]15788719
D000244Adenosine DiphosphateAdenosine Diphosphate inhibits the reaction [[GAPDH protein co-treated with NAD co-treated with Glyceraldehyde 3-Phosphate co-treated with Glutathione] results in increased reduction of sodium arsenite analog]15788719
D000255Adenosine TriphosphateAdenosine Triphosphate inhibits the reaction [[GAPDH protein co-treated with NAD co-treated with Glyceraldehyde 3-Phosphate co-treated with Glutathione] results in increased reduction of sodium arsenite analog]15788719
D000255Adenosine TriphosphateAdenosine Triphosphate inhibits the reaction [[GAPDH protein co-treated with NAD co-treated with Glyceraldehyde 3-Phosphate co-treated with Glutathione] results in increased reduction of sodium arsenite analog]15788719
D016604Aflatoxin B1Aflatoxin B1 results in decreased expression of GAPDH mRNA19770486
C430898AGN 194204AGN 194204 results in decreased expression of GAPDH mRNA16339527
C103303alitretinoinalitretinoin results in decreased expression of GAPDH protein28886987
D053959Alpha-AmanitinAlpha-Amanitin results in decreased expression of GAPDH mRNA26385100
D053959Alpha-AmanitinPolymyxin B inhibits the reaction [Alpha-Amanitin results in decreased expression of GAPDH mRNA]26385100
D000517alpha-Chlorohydrinalpha-Chlorohydrin analog results in decreased expression of GAPDH protein26597043
D000517alpha-Chlorohydrinalpha-Chlorohydrin results in decreased activity of GAPDH protein16322075
D000517alpha-Chlorohydrin[alpha-Chlorohydrin results in decreased activity of GAPDH protein] which results in decreased reduction of Arsenates16322075
D000517alpha-Chlorohydrinalpha-Chlorohydrin results in decreased expression of GAPDH protein26597043
D013196DihydrotestosteroneDihydrotestosterone results in decreased activity of GAPDH protein10650946
D013196Dihydrotestosteronenilutamide inhibits the reaction [Dihydrotestosterone results in decreased activity of GAPDH protein]10650946
C040534alpha-hexachlorocyclohexanealpha-hexachlorocyclohexane affects the expression of GAPDH mRNA16940010
C040534alpha-hexachlorocyclohexanealpha-hexachlorocyclohexane results in decreased expression of GAPDH mRNA16940010
C040534alpha-hexachlorocyclohexanealpha-hexachlorocyclohexane results in increased expression of GAPDH mRNA16940010
D000638AmiodaroneAmiodarone affects the expression of GAPDH mRNA25064622
D000638AmiodaroneAmiodarone affects the expression of GAPDH mRNA19483382
D000643Ammonium ChlorideAmmonium Chloride affects the expression of GAPDH mRNA16483693
D000643Ammonium ChlorideAmmonium Chloride affects the metabolism of GAPDH protein11923223
D000966Antimony Potassium TartrateAntimony Potassium Tartrate results in increased expression of GAPDH mRNA28713220
D001149Arsenates[alpha-Chlorohydrin results in decreased activity of GAPDH protein] which results in decreased reduction of Arsenates16322075
D001149Arsenates[GAPDH protein co-treated with Glutathione] results in increased reduction of Arsenates16322075
D001149Arsenates[[GAPDH protein co-treated with Glutathione] results in increased reduction of Arsenates] which results in increased chemical synthesis of Arsenites16322075
C025657arsenic acid[GAPDH protein co-treated with Glutathione] results in increased chemical synthesis of arsenic acid analog19478237
C025657arsenic acidGAPDH protein results in increased reduction of arsenic acid19248796
C006632arsenic trioxidearsenic trioxide inhibits the reaction [4-aminophenylarsenoxide binds to GAPDH protein]26598702
C006632arsenic trioxidearsenic trioxide results in decreased activity of GAPDH protein15916724
C015001arsenite[[GAPDH protein co-treated with Glutathione] results in increased reduction of sodium arsenate analog] which results in increased chemical synthesis of arsenite19478237
C015001arseniteAcetylcysteine inhibits the reaction [arsenite results in decreased expression of GAPDH protein]15175009
C015001arsenitearsenite results in decreased expression of GAPDH protein15175009
C015001arseniteGlutathione inhibits the reaction [arsenite results in decreased expression of GAPDH protein]15175009
C015001arseniteGAPDH protein results in increased chemical synthesis of arsenite19248796
D018053Arsenites[[GAPDH protein co-treated with Glutathione] results in increased reduction of Arsenates] which results in increased chemical synthesis of Arsenites16322075
D001205Ascorbic AcidAscorbic Acid results in increased expression of GAPDH protein22139585
D001205Ascorbic Acid"Ascorbic Acid affects the reaction [3,4-dihydroxyphenylacetaldehyde binds to and affects the metabolism of GAPDH protein]"19537779
D001280AtrazineAtrazine results in increased expression of GAPDH mRNA25929836
D001553BenzbromaroneBenzbromarone affects the expression of GAPDH mRNA19483382
D019324beta-Naphthoflavonebeta-Naphthoflavone results in increased expression of GAPDH mRNA19850099
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of GAPDH protein17292933
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of GAPDH mRNA19770486
D004958EstradiolEstradiol affects the expression of GAPDH mRNA18214933
C002791bismuth tripotassium dicitratebismuth tripotassium dicitrate results in increased expression of GAPDH mRNA15912405
C551172bis-N,N-dimethylamino-2-(N-methylpyrrolyl)methyl cyclopentadienyl titanium (IV)"bis-N,N-dimethylamino-2-(N-methylpyrrolyl)methyl cyclopentadienyl titanium (IV) results in decreased expression of GAPDH mRNA"20162321
C006780bisphenol Abisphenol A results in increased expression of GAPDH mRNA28159858
C006780bisphenol Abisphenol A affects the expression of GAPDH mRNA18214933
C006780bisphenol A[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of GAPDH mRNA28628672
C006780bisphenol Abisphenol A results in increased expression of GAPDH protein25772901
C006780bisphenol Abisphenol A results in increased expression of GAPDH mRNA25181051
C000611646bisphenol F[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of GAPDH mRNA28628672
C005961bis(tri-n-butyltin)oxidebis(tri-n-butyltin)oxide results in decreased expression of GAPDH mRNA17553608
C032688boric acidboric acid results in decreased expression of GAPDH protein28285642
C099813bromochloroacetic acidbromochloroacetic acid results in increased expression of GAPDH protein21296659
C017092bromopyruvatebromopyruvate results in decreased expression of GAPDH mRNA28433571
C515564bromovaninbromovanin results in decreased expression of GAPDH protein21419150
D019328Buthionine Sulfoximine"[Buthionine Sulfoximine results in decreased abundance of Glutathione] promotes the reaction [1,2-naphthoquinone binds to GAPDH protein]"21827172
D019328Buthionine Sulfoximine"[Buthionine Sulfoximine results in decreased abundance of Glutathione] promotes the reaction [1,2-naphthoquinone results in decreased activity of GAPDH protein]"21827172
D019328Buthionine SulfoximineButhionine Sulfoximine results in increased expression of GAPDH mRNA15878706
D020122tert-Butylhydroperoxidetert-Butylhydroperoxide results in increased expression of GAPDH protein11295360
D020122tert-Butylhydroperoxidetert-Butylhydroperoxide results in increased expression of GAPDH mRNA18804290
D002104CadmiumCadmium results in decreased activity of GAPDH protein16752219
D002104CadmiumCadmium results in increased activity of GAPDH protein16752219
D002104CadmiumCadmium results in decreased activity of GAPDH protein12798935
D002104CadmiumCadmium results in increased expression of GAPDH mRNA17123754
D002104CadmiumCadmium results in decreased activity of GAPDH protein12798935
D019256Cadmium ChlorideCadmium Chloride results in decreased expression of GAPDH protein16249038
D019256Cadmium ChlorideCadmium Chloride results in increased expression of GAPDH protein24527689
D019256Cadmium ChlorideCadmium Chloride results in decreased expression of GAPDH mRNA15967517
D019256Cadmium ChlorideCadmium Chloride results in increased expression of GAPDH mRNA17123754
C034939cadmium sulfide[cadmium telluride co-treated with cadmium sulfide] results in decreased expression of GAPDH mRNA20596552
C028337cadmium telluride[cadmium telluride co-treated with cadmium sulfide] results in decreased expression of GAPDH mRNA20596552
D002110Caffeine"[Caffeine co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in decreased expression of GAPDH mRNA"20230807
D002110Caffeine"Caffeine inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of GAPDH mRNA]"20230807
D002122Calcium Chloride[Sodium Bicarbonate co-treated with Calcium Chloride] results in increased activity of GAPDH protein26582256
D002211CapsaicinCapsaicin results in increased expression of GAPDH protein18991268
D002211CapsaicinCapsaicin inhibits the reaction [Dietary Fats results in increased expression of GAPDH protein]20359164
D002251Carbon TetrachlorideCarbon Tetrachloride results in decreased expression of GAPDH mRNA15963578
D002251Carbon TetrachlorideCarbon Tetrachloride results in increased expression of GAPDH mRNA15240111
D002251Carbon TetrachlorideCarbon Tetrachloride results in increased expression of GAPDH mRNA22563491
D002258Carbonyl Cyanide m-Chlorophenyl HydrazoneCarbonyl Cyanide m-Chlorophenyl Hydrazone inhibits the reaction [[Glucose results in increased chemical synthesis of Superoxides] which results in decreased activity of GAPDH protein]11050244
C026690cerous chloride[cerous chloride co-treated with lanthanum chloride] results in decreased expression of GAPDH mRNA28954213
C026690cerous chloridecerous chloride results in decreased expression of GAPDH mRNA28954213
D002713Chlorine[Ozone co-treated with Chlorine] results in decreased expression of GAPDH mRNA18636392
C004656chloroacetaldehydechloroacetaldehyde results in decreased activity of GAPDH protein19733226
C004656chloroacetaldehyde[chloroacetaldehyde results in decreased activity of GAPDH protein] which results in decreased chemical synthesis of Glucose19733226
C006972chloroacetic acidchloroacetic acid results in decreased activity of GAPDH protein15720133
D020111Chlorodiphenyl (54% Chlorine)Chlorodiphenyl (54% Chlorine) results in increased expression of GAPDH mRNA17851650
D020111Chlorodiphenyl (54% Chlorine)Chlorodiphenyl (54% Chlorine) results in decreased expression of GAPDH mRNA23650126
D020111Chlorodiphenyl (54% Chlorine)Chlorodiphenyl (54% Chlorine) results in increased expression of GAPDH mRNA18804290
D020111Chlorodiphenyl (54% Chlorine)Chlorodiphenyl (54% Chlorine) results in increased expression of GAPDH mRNA18178546
D020111Chlorodiphenyl (54% Chlorine)Chlorodiphenyl (54% Chlorine) results in increased expression of GAPDH protein21791222
D002734Chlorophyll"Chlorophyll inhibits the reaction [dibenzo(a,l)pyrene results in increased expression of GAPDH mRNA]"22079312
C100187chloropicrinchloropicrin results in increased expression of GAPDH mRNA26352163
D002746ChlorpromazineChlorpromazine affects the expression of GAPDH mRNA25064622
C499843chromium histidinatechromium histidinate inhibits the reaction [Hydrogen Peroxide results in increased expression of GAPDH mRNA]19902159
C499843chromium histidinatechromium histidinate results in increased expression of GAPDH mRNA19902159
D002994ClofibrateClofibrate affects the expression of GAPDH mRNA19483382
D003024ClozapineClozapine results in increased expression of GAPDH mRNA15860345
D003033Coal TarCoal Tar results in increased expression of GAPDH protein18495319
C018021cobaltous chloridecobaltous chloride results in increased expression of GAPDH mRNA9486123
C018021cobaltous chloridecobaltous chloride results in increased expression of GAPDH protein9486123
C018021cobaltous chlorideNitroprusside inhibits the reaction [cobaltous chloride results in increased expression of GAPDH mRNA]9486123
C018021cobaltous chlorideNitroprusside inhibits the reaction [cobaltous chloride results in increased expression of GAPDH protein]9486123
C018021cobaltous chloridecobaltous chloride results in increased expression of GAPDH mRNA10646848|1755315
C018021cobaltous chloridetetraethylenepentamine inhibits the reaction [cobaltous chloride results in increased expression of GAPDH mRNA]25100165
C018021cobaltous chloridecobaltous chloride results in increased expression of GAPDH mRNA10646848
C018021cobaltous chlorideHIF1A protein affects the reaction [cobaltous chloride results in increased expression of GAPDH mRNA]10646848
C026305cobalt sulfatecobalt sulfate results in increased expression of GAPDH mRNA19502547
D009243NADAdenosine Diphosphate inhibits the reaction [[GAPDH protein co-treated with NAD co-treated with Glyceraldehyde 3-Phosphate co-treated with Glutathione] results in increased reduction of sodium arsenite analog]15788719
D009243NADAdenosine Triphosphate inhibits the reaction [[GAPDH protein co-treated with NAD co-treated with Glyceraldehyde 3-Phosphate co-treated with Glutathione] results in increased reduction of sodium arsenite analog]15788719
D009243NAD[GAPDH protein co-treated with NAD co-treated with Glyceraldehyde 3-Phosphate co-treated with Glutathione] results in increased reduction of sodium arsenite analog15788719
D009243NADNAD analog inhibits the reaction [[GAPDH protein co-treated with NAD co-treated with Glyceraldehyde 3-Phosphate co-treated with Glutathione] results in increased reduction of sodium arsenite analog]15788719
D009243NADNADP inhibits the reaction [[GAPDH protein co-treated with NAD co-treated with Glyceraldehyde 3-Phosphate co-treated with Glutathione] results in increased reduction of sodium arsenite analog]15788719
D009243NADAdenosine Diphosphate inhibits the reaction [[GAPDH protein co-treated with NAD co-treated with Glyceraldehyde 3-Phosphate co-treated with Glutathione] results in increased reduction of sodium arsenite analog]15788719
D009243NADAdenosine Triphosphate inhibits the reaction [[GAPDH protein co-treated with NAD co-treated with Glyceraldehyde 3-Phosphate co-treated with Glutathione] results in increased reduction of sodium arsenite analog]15788719
D009243NAD[GAPDH protein co-treated with acetyl phosphate co-treated with NAD co-treated with Dithiothreitol] results in increased reduction of sodium arsenate analog19474219
D009243NAD[GAPDH protein co-treated with acetyl phosphate co-treated with NAD co-treated with Glutathione] results in increased reduction of sodium arsenate analog19474219
D009243NAD[GAPDH protein co-treated with acetyl phosphate co-treated with NAD co-treated with Mercaptoethanol] results in increased reduction of sodium arsenate analog19474219
D009243NAD[GAPDH protein co-treated with acetyl phosphate co-treated with NAD co-treated with Succimer] results in increased reduction of sodium arsenate analog19474219
D009243NAD[GAPDH protein co-treated with acetyl phosphate co-treated with NAD co-treated with Unithiol] results in increased reduction of sodium arsenate analog19474219
D009243NAD[GAPDH protein co-treated with NAD co-treated with Glyceraldehyde 3-Phosphate co-treated with Glutathione] results in increased reduction of sodium arsenite analog15788719
D009243NAD[Glyceraldehyde 3-Phosphate co-treated with NAD] inhibits the reaction [heptelidic acid results in decreased activity of GAPDH protein]15788719
D009243NADheptelidic acid inhibits the reaction [[GAPDH protein co-treated with acetyl phosphate co-treated with NAD co-treated with Glutathione] results in increased reduction of sodium arsenate analog]19474219
D009243NADheptelidic acid inhibits the reaction [[GAPDH protein co-treated with NAD co-treated with Glyceraldehyde 3-Phosphate co-treated with Glutathione] results in increased reduction of sodium arsenite analog]15788719
D009243NADNAD analog inhibits the reaction [[GAPDH protein co-treated with NAD co-treated with Glyceraldehyde 3-Phosphate co-treated with Glutathione] results in increased reduction of sodium arsenite analog]15788719
D009243NADNADP inhibits the reaction [[GAPDH protein co-treated with NAD co-treated with Glyceraldehyde 3-Phosphate co-treated with Glutathione] results in increased reduction of sodium arsenite analog]15788719
D009243NAD[GAPDH protein co-treated with 3-phosphoglycerate co-treated with NAD] results in increased chemical synthesis of sodium arsenite15788719
D009243NAD[GAPDH protein co-treated with 3-phosphoglycerate co-treated with NAD] results in increased reduction of sodium arsenate analog15788719
D009243NAD"[GAPDH protein co-treated with fructose-1,6-diphosphate co-treated with NAD] results in increased chemical synthesis of sodium arsenite"15788719
D009243NAD"[GAPDH protein co-treated with fructose-1,6-diphosphate co-treated with NAD] results in increased reduction of sodium arsenate analog"15788719
D009243NADheptelidic acid inhibits the reaction [[GAPDH protein co-treated with 3-phosphoglycerate co-treated with NAD] results in increased reduction of sodium arsenate analog]15788719
D009243NAD"heptelidic acid inhibits the reaction [[GAPDH protein co-treated with fructose-1,6-diphosphate co-treated with NAD] results in increased reduction of sodium arsenate analog]"15788719
D009243NAD[ITPR1 protein binds to GAPDH protein] which results in increased abundance of NAD15677321
D009249NADPNADP inhibits the reaction [[GAPDH protein co-treated with NAD co-treated with Glyceraldehyde 3-Phosphate co-treated with Glutathione] results in increased reduction of sodium arsenite analog]15788719
D009249NADPNADP inhibits the reaction [[GAPDH protein co-treated with NAD co-treated with Glyceraldehyde 3-Phosphate co-treated with Glutathione] results in increased reduction of sodium arsenite analog]15788719
D003300CopperGAPDH protein binds to Copper14534351|1535973
D003300CopperCopper results in decreased activity of GAPDH protein12798935
D003300CopperCopper results in decreased activity of GAPDH protein12798935
D003300CopperCopper results in increased oxidation of and results in increased degradation of [dopamine quinone binds to GAPDH protein]17154550
D019327Copper SulfateCopper Sulfate results in increased expression of GAPDH mRNA25216733
C007164cumene hydroperoxidecumene hydroperoxide results in increased expression of GAPDH protein11295360
C029892cupric chloridecupric chloride results in increased expression of GAPDH protein22699969
D003513CycloheximideCycloheximide inhibits the reaction [Oxygen deficiency results in increased expression of GAPDH mRNA]9486123
D016572CyclosporineCyclosporine affects the expression of GAPDH mRNA25064622
D016572CyclosporineCyclosporine results in increased expression of GAPDH mRNA19770486
D003561CytarabineCytarabine affects the localization of GAPDH protein19628630
D003561CytarabineCytarabine results in decreased activity of GAPDH protein19628630
D003561CytarabineGAPDH protein results in increased susceptibility to Cytarabine19628630
D003609DactinomycinDactinomycin results in increased expression of GAPDH mRNA16001973
C014347decitabinedecitabine results in decreased expression of GAPDH protein19294695
C014347decitabinedecitabine results in increased expression of GAPDH mRNA17908484
C014347decitabinedecitabine results in increased expression of GAPDH mRNA27915011
D003676DeferoxamineDeferoxamine results in increased expression of GAPDH mRNA9486123
D003676DeferoxamineDeferoxamine results in increased expression of GAPDH protein9486123
D003676DeferoxamineDeferoxamine results in decreased expression of GAPDH protein19515424
D003676Deferoxamineferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of GAPDH protein]19515424
D013759DronabinolDronabinol results in increased expression of GAPDH protein18163980
D013759DronabinolDronabinol results in decreased expression of GAPDH mRNA11015613
D003907Dexamethasone[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of GAPDH mRNA28628672
D003907Dexamethasone[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of GAPDH mRNA28628672
C042577diallyl trisulfidediallyl trisulfide results in decreased expression of GAPDH protein16344271
D003976DiazinonDiazinon affects the expression of GAPDH mRNA22546817
C041517dibenzo(a,l)pyrene"Chlorophyll inhibits the reaction [dibenzo(a,l)pyrene results in increased expression of GAPDH mRNA]"22079312
C041517dibenzo(a,l)pyrene"dibenzo(a,l)pyrene results in increased expression of GAPDH mRNA"22079312
D003993Dibutyl PhthalateDibutyl Phthalate results in decreased expression of GAPDH mRNA21266533
D003993Dibutyl PhthalateDibutyl Phthalate results in decreased expression of GAPDH mRNA17379624|2126653
D002945CisplatinCisplatin results in increased expression of GAPDH protein21924258
D004026DieldrinDieldrin results in decreased expression of GAPDH mRNA23041725
D004041Dietary FatsDietary Fats results in decreased expression of GAPDH mRNA19030233
D004041Dietary FatsCapsaicin inhibits the reaction [Dietary Fats results in increased expression of GAPDH protein]20359164
D004041Dietary FatsDietary Fats results in increased expression of GAPDH protein20359164
C014476diethyl maleatediethyl maleate results in increased reduction of GAPDH protein19843705
D004052DiethylnitrosamineDiethylnitrosamine results in increased expression of GAPDH mRNA20360939
C039060dihydroartemisinindihydroartemisinin analog binds to GAPDH protein26340163
C042080diisodecyl phthalatediisodecyl phthalate results in increased expression of GAPDH mRNA25270620
D0151279,10-Dimethyl-1,2-benzanthracene"9,10-Dimethyl-1,2-benzanthracene results in decreased expression of GAPDH mRNA"19502547
D0151279,10-Dimethyl-1,2-benzanthracene"9,10-Dimethyl-1,2-benzanthracene results in decreased expression of GAPDH mRNA"22485181
D0151279,10-Dimethyl-1,2-benzanthracene"[9,10-Dimethyl-1,2-benzanthracene co-treated with Isoflavones] results in increased expression of GAPDH protein"22248470
D0151279,10-Dimethyl-1,2-benzanthracene"9,10-Dimethyl-1,2-benzanthracene results in increased expression of GAPDH protein"22248470
D004121Dimethyl SulfoxideDimethyl Sulfoxide affects the expression of GAPDH mRNA12843640
D004229DithiothreitolDithiothreitol inhibits the reaction [S-Nitroso-N-Acetylpenicillamine results in increased metabolism of [GAPDH protein binds to GAPDH protein binds to GAPDH protein binds to GAPDH protein]]10403526
D004229Dithiothreitol[GAPDH protein co-treated with acetyl phosphate co-treated with NAD co-treated with Dithiothreitol] results in increased reduction of sodium arsenate analog19474219
D004229Dithiothreitol[[Nitroprusside results in increased abundance of Nitric Oxide] which co-treated with Dithiothreitol] results in decreased activity of [GAPDH protein binds to GAPDH protein binds to GAPDH protein binds to GAPDH protein]10403526
D004229Dithiothreitol[sodium arsenite co-treated with Dithiothreitol] inhibits the reaction [Hydrogen Peroxide results in decreased activity of [GAPDH protein binds to GAPDH protein binds to GAPDH protein binds to GAPDH protein]]10403526
D004229Dithiothreitol[sodium arsenite co-treated with Dithiothreitol] inhibits the reaction [Nitroprusside results in decreased activity of [GAPDH protein binds to GAPDH protein binds to GAPDH protein binds to GAPDH protein]]10403526
D004229Dithiothreitol[sodium arsenite co-treated with Dithiothreitol] inhibits the reaction [S-Nitroso-N-Acetylpenicillamine results in decreased activity of [GAPDH protein binds to GAPDH protein binds to GAPDH protein binds to GAPDH protein]]10403526
D016291Dizocilpine MaleateDizocilpine Maleate results in increased expression of GAPDH protein21297352
C067311docetaxel[docetaxel co-treated with Doxorubicin] results in increased expression of GAPDH protein20457137
D004298DopamineDopamine results in increased expression of GAPDH protein24675778
C104705dopamine quinoneCopper results in increased oxidation of and results in increased degradation of [dopamine quinone binds to GAPDH protein]17154550
C104705dopamine quinonedopamine quinone binds to GAPDH protein17154550
D004317Doxorubicin[docetaxel co-treated with Doxorubicin] results in increased expression of GAPDH protein20457137
C070609EMD 53998EMD 53998 analog results in increased expression of GAPDH mRNA24977338
C013525ENNG[ENNG co-treated with Isoflavones] results in increased expression of GAPDH protein22248470
C013525ENNGENNG results in increased expression of GAPDH protein22248470
D004791Enzyme Inhibitors[Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation of GAPDH protein23301498
D000431EthanolEthanol results in decreased expression of and results in decreased activity of GAPDH protein28962519
D000431EthanolEthanol results in decreased expression of GAPDH mRNA28962519
D000431Ethanoltetrakis(N-methyl-4-pyridiniumyl)porphine manganese(III) complex inhibits the reaction [Ethanol results in decreased activity of GAPDH protein]28962519
D000431Ethanoltetrakis(N-methyl-4-pyridiniumyl)porphine manganese(III) complex inhibits the reaction [Ethanol results in decreased expression of GAPDH mRNA]28962519
D000431EthanolEthanol results in decreased expression of GAPDH protein12700235
D000431EthanolEthanol results in increased expression of GAPDH protein23702218
D004997Ethinyl EstradiolEthinyl Estradiol results in increased expression of GAPDH mRNA16954407
D004997Ethinyl EstradiolEthinyl Estradiol affects the expression of GAPDH mRNA16872691|2506462
D004997Ethinyl EstradiolEthinyl Estradiol results in decreased expression of GAPDH mRNA20227414
D004997Ethinyl EstradiolEthinyl Estradiol results in decreased expression of GAPDH mRNA17288598
D004997Ethinyl EstradiolEthinyl Estradiol results in increased expression of GAPDH mRNA10822019|1755790
D005001EthionineEthionine affects the expression of GAPDH mRNA19483382
C504383fenbuconazolefenbuconazole results in increased expression of GAPDH mRNA15942997
C013531ferric ammonium citrateferric ammonium citrate inhibits the reaction [Deferoxamine results in increased expression of GAPDH protein]19515424
D005411Flame RetardantsFlame Retardants results in decreased expression of GAPDH protein18550172
D005419FlavonoidsFlavonoids results in decreased expression of GAPDH mRNA18035473
D005472FluorouracilFluorouracil affects the splicing of GAPDH mRNA17169984
D005472FluorouracilFluorouracil results in decreased expression of GAPDH protein21296659
D005485FlutamideFlutamide results in increased expression of GAPDH mRNA21525395|2413618
D005609Free Radicals[Hydroxyurea results in increased abundance of Free Radicals] promotes the reaction [4-hydroxy-2-nonenal binds to GAPDH protein]23696560
C029063fructose-1,6-diphosphate"[GAPDH protein co-treated with fructose-1,6-diphosphate co-treated with NAD] results in increased chemical synthesis of sodium arsenite"15788719
C029063fructose-1,6-diphosphate"[GAPDH protein co-treated with fructose-1,6-diphosphate co-treated with NAD] results in increased reduction of sodium arsenate analog"15788719
C029063fructose-1,6-diphosphate"heptelidic acid inhibits the reaction [[GAPDH protein co-treated with fructose-1,6-diphosphate co-treated with NAD] results in increased reduction of sodium arsenate analog]"15788719
C039281furanfuran affects the activity of GAPDH protein27402187
C039281furanfuran binds to GAPDH protein22240984
C039281furanfuran results in increased expression of GAPDH mRNA15120968
D019833GenisteinGenistein results in increased expression of GAPDH mRNA17341692
C063170Ginkgo biloba extractGinkgo biloba extract inhibits the reaction [3-nitropropionic acid results in increased expression of GAPDH mRNA]21827809
D005897GlafenineGlafenine results in increased expression of GAPDH mRNA24136188
D005947GlucoseCarbonyl Cyanide m-Chlorophenyl Hydrazone inhibits the reaction [[Glucose results in increased chemical synthesis of Superoxides] which results in decreased activity of GAPDH protein]11050244
D005947GlucoseGlucose results in decreased activity of GAPDH protein11050244
D005947Glucose[Glucose results in increased chemical synthesis of Superoxides] which results in decreased activity of GAPDH protein11050244
D005947Glucosemanganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [[Glucose results in increased chemical synthesis of Superoxides] which results in decreased activity of GAPDH protein]11050244
D005947GlucoseThenoyltrifluoroacetone inhibits the reaction [[Glucose results in increased chemical synthesis of Superoxides] which results in decreased activity of GAPDH protein]11050244
D005947GlucoseGlucose results in increased expression of GAPDH mRNA7826318
D005947GlucoseSOD2 protein inhibits the reaction [[Glucose results in increased chemical synthesis of Superoxides] which results in decreased activity of GAPDH protein]11050244
D005947Glucose[chloroacetaldehyde results in decreased activity of GAPDH protein] which results in decreased chemical synthesis of Glucose19733226
D005947GlucoseUCP1 protein inhibits the reaction [[Glucose results in increased chemical synthesis of Superoxides] which results in decreased activity of GAPDH protein]11050244
D005978GlutathioneGlutathione inhibits the reaction [[Acrolein affects the metabolism of ALB protein] which results in decreased activity of GAPDH protein]12032148
D005978GlutathioneAdenosine Diphosphate inhibits the reaction [[GAPDH protein co-treated with NAD co-treated with Glyceraldehyde 3-Phosphate co-treated with Glutathione] results in increased reduction of sodium arsenite analog]15788719
D005978GlutathioneAdenosine Triphosphate inhibits the reaction [[GAPDH protein co-treated with NAD co-treated with Glyceraldehyde 3-Phosphate co-treated with Glutathione] results in increased reduction of sodium arsenite analog]15788719
D005978Glutathione"[Buthionine Sulfoximine results in decreased abundance of Glutathione] promotes the reaction [1,2-naphthoquinone binds to GAPDH protein]"21827172
D005978Glutathione"[Buthionine Sulfoximine results in decreased abundance of Glutathione] promotes the reaction [1,2-naphthoquinone results in decreased activity of GAPDH protein]"21827172
D005978Glutathione[GAPDH protein co-treated with NAD co-treated with Glyceraldehyde 3-Phosphate co-treated with Glutathione] results in increased reduction of sodium arsenite analog15788719
D005978GlutathioneGlutathione results in increased metabolism of and results in increased activity of GAPDH protein modified form21827172
D005978GlutathioneNAD analog inhibits the reaction [[GAPDH protein co-treated with NAD co-treated with Glyceraldehyde 3-Phosphate co-treated with Glutathione] results in increased reduction of sodium arsenite analog]15788719
D005978GlutathioneNADP inhibits the reaction [[GAPDH protein co-treated with NAD co-treated with Glyceraldehyde 3-Phosphate co-treated with Glutathione] results in increased reduction of sodium arsenite analog]15788719
D005978GlutathioneAdenosine Diphosphate inhibits the reaction [[GAPDH protein co-treated with NAD co-treated with Glyceraldehyde 3-Phosphate co-treated with Glutathione] results in increased reduction of sodium arsenite analog]15788719
D005978GlutathioneAdenosine Triphosphate inhibits the reaction [[GAPDH protein co-treated with NAD co-treated with Glyceraldehyde 3-Phosphate co-treated with Glutathione] results in increased reduction of sodium arsenite analog]15788719
D005978Glutathione[GAPDH protein co-treated with acetyl phosphate co-treated with NAD co-treated with Glutathione] results in increased reduction of sodium arsenate analog19474219
D005978Glutathione[GAPDH protein co-treated with Glutathione] results in increased chemical synthesis of arsenic acid analog19478237
D005978Glutathione[GAPDH protein co-treated with Glutathione] results in increased reduction of sodium arsenate analog19478237
D005978Glutathione[[GAPDH protein co-treated with Glutathione] results in increased reduction of sodium arsenate analog] which results in increased chemical synthesis of arsenite19478237
D005978Glutathione[GAPDH protein co-treated with NAD co-treated with Glyceraldehyde 3-Phosphate co-treated with Glutathione] results in increased reduction of sodium arsenite analog15788719
D005978Glutathioneheptelidic acid inhibits the reaction [[GAPDH protein co-treated with acetyl phosphate co-treated with NAD co-treated with Glutathione] results in increased reduction of sodium arsenate analog]19474219
D005978Glutathioneheptelidic acid inhibits the reaction [[GAPDH protein co-treated with NAD co-treated with Glyceraldehyde 3-Phosphate co-treated with Glutathione] results in increased reduction of sodium arsenite analog]15788719
D005978GlutathioneNAD analog inhibits the reaction [[GAPDH protein co-treated with NAD co-treated with Glyceraldehyde 3-Phosphate co-treated with Glutathione] results in increased reduction of sodium arsenite analog]15788719
D005978GlutathioneNADP inhibits the reaction [[GAPDH protein co-treated with NAD co-treated with Glyceraldehyde 3-Phosphate co-treated with Glutathione] results in increased reduction of sodium arsenite analog]15788719
D005978GlutathioneGlutathione inhibits the reaction [arsenite results in decreased expression of GAPDH protein]15175009
D005978Glutathione[GAPDH protein co-treated with Glutathione] results in increased reduction of Arsenates16322075
D005978Glutathione[[GAPDH protein co-treated with Glutathione] results in increased reduction of Arsenates] which results in increased chemical synthesis of Arsenites16322075
D006046GoldGold analog results in decreased expression of GAPDH protein24780912
D006108GraphiteGraphite results in decreased expression of GAPDH protein22157353
D006220HaloperidolHaloperidol results in increased expression of GAPDH mRNA15860345
C027285heptelidic acid[Glyceraldehyde 3-Phosphate co-treated with NAD] inhibits the reaction [heptelidic acid results in decreased activity of GAPDH protein]15788719
C027285heptelidic acidGlyceraldehyde 3-Phosphate inhibits the reaction [heptelidic acid results in decreased activity of GAPDH protein]15788719
C027285heptelidic acidheptelidic acid inhibits the reaction [[GAPDH protein co-treated with acetyl phosphate co-treated with NAD co-treated with Glutathione] results in increased reduction of sodium arsenate analog]19474219
C027285heptelidic acidheptelidic acid inhibits the reaction [[GAPDH protein co-treated with NAD co-treated with Glyceraldehyde 3-Phosphate co-treated with Glutathione] results in increased reduction of sodium arsenite analog]15788719
C027285heptelidic acidheptelidic acid results in decreased activity of GAPDH protein15788719|1947823
C027285heptelidic acidheptelidic acid inhibits the reaction [[GAPDH protein co-treated with 3-phosphoglycerate co-treated with NAD] results in increased reduction of sodium arsenate analog]15788719
C027285heptelidic acid"heptelidic acid inhibits the reaction [[GAPDH protein co-treated with fructose-1,6-diphosphate co-treated with NAD] results in increased reduction of sodium arsenate analog]"15788719
C027285heptelidic acidheptelidic acid results in decreased activity of GAPDH protein15788719
D012701Serotonin[MPO protein co-treated with XDH protein co-treated with Acetaldehyde co-treated with Serotonin] affects the metabolism of and binds to GAPDH protein23009681
D012701Serotonin"[tryptamine-4,5-dione co-treated with Serotonin] affects the metabolism of and binds to GAPDH protein"23009681
D006861Hydrogen Peroxidechromium histidinate inhibits the reaction [Hydrogen Peroxide results in increased expression of GAPDH mRNA]19902159
D006861Hydrogen PeroxideHydrogen Peroxide results in decreased expression of GAPDH mRNA12419474
D006861Hydrogen PeroxideHydrogen Peroxide results in increased expression of GAPDH mRNA19902159
D006861Hydrogen PeroxideHydrogen Peroxide results in increased expression of GAPDH protein11295360
D006861Hydrogen PeroxideHydrogen Peroxide affects the expression of GAPDH protein16876868
D006861Hydrogen PeroxideHydrogen Peroxide results in decreased activity of [GAPDH protein binds to GAPDH protein binds to GAPDH protein binds to GAPDH protein]10403526
D006861Hydrogen Peroxide[sodium arsenite co-treated with Dithiothreitol] inhibits the reaction [Hydrogen Peroxide results in decreased activity of [GAPDH protein binds to GAPDH protein binds to GAPDH protein binds to GAPDH protein]]10403526
D006918HydroxyureaHydroxyurea affects the localization of GAPDH protein20889679
D006918HydroxyureaHydroxyurea affects the metabolism of and results in decreased activity of and affects the localization of GAPDH protein23696560
D006918HydroxyureaHydroxyurea promotes the reaction [4-hydroxy-2-nonenal binds to GAPDH protein]20889679
D006918Hydroxyurea[Hydroxyurea promotes the reaction [4-hydroxy-2-nonenal binds to GAPDH protein]] which results in decreased activity of GAPDH protein20889679
D006918HydroxyureaHydroxyurea results in decreased activity of GAPDH protein20889679
D006918Hydroxyurea[Hydroxyurea results in increased abundance of Free Radicals] promotes the reaction [4-hydroxy-2-nonenal binds to GAPDH protein]23696560
D006918HydroxyureaSelegiline inhibits the reaction [Hydroxyurea affects the localization of GAPDH protein]23696560
C428264indioside Dindioside D results in decreased expression of GAPDH protein18376857
C020758indium trichlorideindium trichloride results in decreased expression of GAPDH protein19539025
D007213Indomethacin[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of GAPDH mRNA28628672
D007213Indomethacin[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of GAPDH mRNA28628672
D007461IodoacetatesIodoacetates results in decreased activity of GAPDH protein22539072
D0150561-Methyl-3-isobutylxanthine[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of GAPDH mRNA28628672
D0150561-Methyl-3-isobutylxanthine[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of GAPDH mRNA28628672
D007529Isoflavones"[9,10-Dimethyl-1,2-benzanthracene co-treated with Isoflavones] results in increased expression of GAPDH protein"22248470
D007529Isoflavones[ENNG co-treated with Isoflavones] results in increased expression of GAPDH protein22248470
D007538IsoniazidIsoniazid results in increased expression of GAPDH mRNA12883083
C544151jinfukangjinfukang results in increased expression of GAPDH mRNA27392435
C098607JP8 aviation fuelJP8 aviation fuel results in increased expression of GAPDH protein16323059
C561695(+)-JQ1 compound(+)-JQ1 compound results in decreased expression of GAPDH mRNA25961927
C410337K 7174K 7174 results in decreased expression of GAPDH mRNA24086573
C028521lanthanum chloride[cerous chloride co-treated with lanthanum chloride] results in decreased expression of GAPDH mRNA28954213
D007854LeadGAPDH protein binds to Lead23896426
C008261lead acetatelead acetate results in increased expression of GAPDH protein20797405
C025340manganese chloridemanganese chloride results in increased expression of GAPDH mRNA9486123
C025340manganese chloridemanganese chloride results in increased expression of GAPDH protein9486123
C025340manganese chlorideNitroprusside inhibits the reaction [manganese chloride results in increased expression of GAPDH mRNA]9486123
C025340manganese chlorideNitroprusside inhibits the reaction [manganese chloride results in increased expression of GAPDH protein]9486123
C097284manganese(III)-tetrakis(4-benzoic acid)porphyrinmanganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [[Glucose results in increased chemical synthesis of Superoxides] which results in decreased activity of GAPDH protein]11050244
D008623Mercaptoethanol[GAPDH protein co-treated with acetyl phosphate co-treated with NAD co-treated with Mercaptoethanol] results in increased reduction of sodium arsenate analog19474219
D015122MercaptopurineMercaptopurine affects the localization of GAPDH protein19628630
D008628MercuryMercury results in decreased activity of GAPDH protein16752219
D008628MercuryMercury results in increased activity of GAPDH protein16752219
D000432MethanolMethanol results in decreased expression of GAPDH protein22257634
D008713MethimazoleMethimazole results in increased expression of GAPDH mRNA17403546
D008731MethoxychlorMethoxychlor results in increased methylation of GAPDH gene23303685
C005219methyl cellosolvemethyl cellosolve results in increased expression of GAPDH mRNA19643169
C004925methylmercuric chloridemethylmercuric chloride results in decreased expression of GAPDH mRNA22265609
C004925methylmercuric chloridemethylmercuric chloride results in decreased expression of GAPDH protein22265609
D008767Methylmercury CompoundsMethylmercury Compounds results in increased expression of GAPDH mRNA27544571
D008767Methylmercury CompoundsMethylmercury Compounds results in decreased expression of GAPDH mRNA19150642
D008767Methylmercury CompoundsMethylmercury Compounds results in increased expression of GAPDH mRNA16966085
D0156551-Methyl-4-phenylpyridinium1-Methyl-4-phenylpyridinium results in increased expression of GAPDH mRNA14724376
D0156551-Methyl-4-phenylpyridinium1-Methyl-4-phenylpyridinium results in increased expression of GAPDH protein24675778
D0156551-Methyl-4-phenylpyridiniumSelegiline inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of GAPDH mRNA]14724376
D0156551-Methyl-4-phenylpyridinium1-Methyl-4-phenylpyridinium results in decreased expression of GAPDH mRNA22776087
D0156321-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine"1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of GAPDH mRNA"20230807
D0156321-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine"[Caffeine co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in decreased expression of GAPDH mRNA"20230807
D0156321-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine"Caffeine inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of GAPDH mRNA]"20230807
D0156321-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine"[Nicotine co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in decreased expression of GAPDH mRNA"20230807
D0156321-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine"Nicotine inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of GAPDH mRNA]"20230807
C016599mono-(2-ethylhexyl)phthalatemono-(2-ethylhexyl)phthalate results in increased expression of GAPDH protein25543134|2738497
D009020MorphineMorphine results in decreased expression of GAPDH protein23056601
D009151Mustard GasMustard Gas affects the localization of GAPDH protein23827652
D009151Mustard GasMustard Gas results in increased expression of GAPDH protein23827652
D009151Mustard GasMustard Gas affects the expression of GAPDH mRNA15651846
D009151Mustard GasMustard Gas results in increased expression of GAPDH mRNA18988085
D037742Nanotubes, Carbon"Nanotubes, Carbon affects the expression of GAPDH protein"22001959
D037742Nanotubes, Carbon"Nanotubes, Carbon results in increased expression of GAPDH protein"22157353
D037742Nanotubes, Carbon"Nanotubes, Carbon affects the expression of GAPDH mRNA"25620056
D037742Nanotubes, Carbon"Nanotubes, Carbon analog affects the expression of GAPDH mRNA"25620056
D037742Nanotubes, Carbon"Nanotubes, Carbon analog results in increased expression of GAPDH mRNA"25554681
D037742Nanotubes, Carbon"Nanotubes, Carbon results in increased expression of GAPDH mRNA"25554681
C022838nickel chloridenickel chloride results in increased expression of GAPDH mRNA9486123
C022838nickel chloridenickel chloride results in increased expression of GAPDH protein9486123
C022838nickel chlorideNitroprusside inhibits the reaction [nickel chloride results in increased expression of GAPDH mRNA]9486123
C022838nickel chlorideNitroprusside inhibits the reaction [nickel chloride results in increased expression of GAPDH protein]9486123
C022838nickel chloridenickel chloride results in increased expression of GAPDH mRNA10646848|2356695
C022838nickel chlorideHIF1A affects the reaction [nickel chloride results in increased expression of GAPDH mRNA]12426141
C022838nickel chlorideHIF1A protein affects the reaction [nickel chloride results in increased expression of GAPDH mRNA]10646848
C022838nickel chloridenickel chloride results in increased expression of GAPDH mRNA10646848|1242614
C022838nickel chloridenickel chloride affects the expression of GAPDH mRNA22546817
C028007nickel monoxidenickel monoxide results in increased expression of GAPDH mRNA19167457
C029938nickel sulfatenickel sulfate affects the expression of GAPDH mRNA12718980
D009538Nicotine"[Nicotine co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in decreased expression of GAPDH mRNA"20230807
D009538Nicotine"Nicotine inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of GAPDH mRNA]"20230807
C021277nilutamidenilutamide inhibits the reaction [Dihydrotestosterone results in decreased activity of GAPDH protein]10650946
D009569Nitric OxideNitric Oxide deficiency results in increased expression of GAPDH mRNA15878706
D009569Nitric OxideNitric Oxide results in decreased activity of GAPDH protein10403526
D009569Nitric Oxide[[Nitroprusside results in increased abundance of Nitric Oxide] which co-treated with Dithiothreitol] results in decreased activity of [GAPDH protein binds to GAPDH protein binds to GAPDH protein binds to GAPDH protein]10403526
D009569Nitric Oxide[S-Nitroso-N-Acetylpenicillamine results in increased abundance of Nitric Oxide] results in decreased activity of [GAPDH protein binds to GAPDH protein binds to GAPDH protein binds to GAPDH protein]10403526
D009569Nitric OxideSulfenic Acids affects the reaction [Nitric Oxide results in decreased activity of GAPDH protein]10403526
D009569Nitric Oxide[7-nitroindazole results in decreased chemical synthesis of Nitric Oxide] inhibits the reaction [Paraquat affects the localization of GAPDH protein]20478973
D009599NitroprussideNitroprusside inhibits the reaction [cobaltous chloride results in increased expression of GAPDH mRNA]9486123
D009599NitroprussideNitroprusside inhibits the reaction [cobaltous chloride results in increased expression of GAPDH protein]9486123
D009599NitroprussideNitroprusside inhibits the reaction [manganese chloride results in increased expression of GAPDH mRNA]9486123
D009599NitroprussideNitroprusside inhibits the reaction [manganese chloride results in increased expression of GAPDH protein]9486123
D009599NitroprussideNitroprusside inhibits the reaction [nickel chloride results in increased expression of GAPDH mRNA]9486123
D009599NitroprussideNitroprusside inhibits the reaction [nickel chloride results in increased expression of GAPDH protein]9486123
D009599NitroprussideNitroprusside inhibits the reaction [Oxygen deficiency results in increased expression of GAPDH mRNA]9486123
D009599NitroprussideNitroprusside inhibits the reaction [Oxygen deficiency results in increased expression of GAPDH protein]9486123
D009599NitroprussideNitroprusside results in decreased activity of [GAPDH protein binds to GAPDH protein binds to GAPDH protein binds to GAPDH protein]10403526
D009599Nitroprusside[[Nitroprusside results in increased abundance of Nitric Oxide] which co-treated with Dithiothreitol] results in decreased activity of [GAPDH protein binds to GAPDH protein binds to GAPDH protein binds to GAPDH protein]10403526
D009599Nitroprusside[sodium arsenite co-treated with Dithiothreitol] inhibits the reaction [Nitroprusside results in decreased activity of [GAPDH protein binds to GAPDH protein binds to GAPDH protein binds to GAPDH protein]]10403526
D026423S-Nitroso-N-AcetylpenicillamineDithiothreitol inhibits the reaction [S-Nitroso-N-Acetylpenicillamine results in increased metabolism of [GAPDH protein binds to GAPDH protein binds to GAPDH protein binds to GAPDH protein]]10403526
D026423S-Nitroso-N-Acetylpenicillamine[S-Nitroso-N-Acetylpenicillamine results in increased abundance of Nitric Oxide] results in decreased activity of [GAPDH protein binds to GAPDH protein binds to GAPDH protein binds to GAPDH protein]10403526
D026423S-Nitroso-N-AcetylpenicillamineS-Nitroso-N-Acetylpenicillamine results in increased metabolism of [GAPDH protein binds to GAPDH protein binds to GAPDH protein binds to GAPDH protein]10403526
D026423S-Nitroso-N-Acetylpenicillamine[sodium arsenite co-treated with Dithiothreitol] inhibits the reaction [S-Nitroso-N-Acetylpenicillamine results in decreased activity of [GAPDH protein binds to GAPDH protein binds to GAPDH protein binds to GAPDH protein]]10403526
D026423S-Nitroso-N-Acetylpenicillaminesodium arsenite inhibits the reaction [S-Nitroso-N-Acetylpenicillamine results in increased metabolism of [GAPDH protein binds to GAPDH protein binds to GAPDH protein binds to GAPDH protein]]10403526
C014707nitrosobenzylmethylaminenitrosobenzylmethylamine results in increased expression of GAPDH mRNA17616710
C002741N-nitrosomorpholineN-nitrosomorpholine results in increased expression of GAPDH protein19716841
C510003nordynordy results in increased expression of GAPDH protein18232056
C464660obeticholic acidobeticholic acid results in decreased expression of GAPDH mRNA27939613
D019319Okadaic AcidOkadaic Acid affects the expression of GAPDH mRNA22788371
D009853OmeprazoleOmeprazole affects the expression of GAPDH mRNA19483382
D010100OxygenCycloheximide inhibits the reaction [Oxygen deficiency results in increased expression of GAPDH mRNA]9486123
D010100OxygenNitroprusside inhibits the reaction [Oxygen deficiency results in increased expression of GAPDH mRNA]9486123
D010100OxygenNitroprusside inhibits the reaction [Oxygen deficiency results in increased expression of GAPDH protein]9486123
D010100OxygenOxygen deficiency results in increased expression of GAPDH mRNA9486123
D010100OxygenOxygen deficiency results in increased expression of GAPDH protein9486123
D010100OxygenOxygen deficiency results in decreased expression of GAPDH protein19579223
D010100OxygenOxygen deficiency results in increased expression of GAPDH mRNA10646848|1950254
D010100OxygenHIF1A protein affects the reaction [Oxygen deficiency results in increased expression of GAPDH mRNA]10646848
D010100OxygenOxygen deficiency results in increased expression of GAPDH mRNA10646848
D010100OxygenOxygen deficiency results in increased expression of GAPDH mRNA15967517
D010100OxygenOxygen results in increased expression of GAPDH mRNA22911455
D010126Ozone[Ozone co-treated with Chlorine] results in decreased expression of GAPDH mRNA18636392
D010269ParaquatParaquat affects the expression of GAPDH mRNA25064622
D010269Paraquat[7-nitroindazole results in decreased chemical synthesis of Nitric Oxide] inhibits the reaction [Paraquat affects the localization of GAPDH protein]20478973
D010269ParaquatParaquat affects the localization of GAPDH protein20478973
D010269ParaquatSelegiline inhibits the reaction [Paraquat affects the localization of GAPDH protein]20478973
D010269ParaquatParaquat results in decreased activity of GAPDH protein11814328|1705521
D010269ParaquatSelenium inhibits the reaction [Paraquat results in decreased activity of GAPDH protein]17055214
D052638Particulate MatterParticulate Matter results in decreased expression of GAPDH mRNA24769257
C086401pentabromodiphenyl etherpentabromodiphenyl ether results in decreased expression of GAPDH protein18550172
C086401pentabromodiphenyl etherpentabromodiphenyl ether results in decreased expression of GAPDH protein19954255
C086401pentabromodiphenyl etherpentabromodiphenyl ether results in increased expression of GAPDH protein19954255|2561625
C494474perchlorateperchlorate results in increased expression of GAPDH mRNA17403546
C471071perfluorohexanesulfonic acidperfluorohexanesulfonic acid results in increased expression of GAPDH mRNA23567314
C076994perfluorooctane sulfonic acidperfluorooctane sulfonic acid affects the expression of GAPDH mRNA19429403
C023036perfluorooctanoic acidperfluorooctanoic acid affects the expression of GAPDH mRNA19429403
C023036perfluorooctanoic acidperfluorooctanoic acid results in increased expression of GAPDH mRNA18804290
C023036perfluorooctanoic acidperfluorooctanoic acid results in increased expression of GAPDH mRNA21723365
C023036perfluorooctanoic acidperfluorooctanoic acid results in increased expression of GAPDH protein19616056
D010575PesticidesPesticides results in decreased methylation of GAPDH gene28396702
D005986Glyceraldehyde 3-PhosphateAdenosine Diphosphate inhibits the reaction [[GAPDH protein co-treated with NAD co-treated with Glyceraldehyde 3-Phosphate co-treated with Glutathione] results in increased reduction of sodium arsenite analog]15788719
D005986Glyceraldehyde 3-PhosphateAdenosine Triphosphate inhibits the reaction [[GAPDH protein co-treated with NAD co-treated with Glyceraldehyde 3-Phosphate co-treated with Glutathione] results in increased reduction of sodium arsenite analog]15788719
D005986Glyceraldehyde 3-Phosphate[GAPDH protein co-treated with NAD co-treated with Glyceraldehyde 3-Phosphate co-treated with Glutathione] results in increased reduction of sodium arsenite analog15788719
D005986Glyceraldehyde 3-PhosphateNAD analog inhibits the reaction [[GAPDH protein co-treated with NAD co-treated with Glyceraldehyde 3-Phosphate co-treated with Glutathione] results in increased reduction of sodium arsenite analog]15788719
D005986Glyceraldehyde 3-PhosphateNADP inhibits the reaction [[GAPDH protein co-treated with NAD co-treated with Glyceraldehyde 3-Phosphate co-treated with Glutathione] results in increased reduction of sodium arsenite analog]15788719
D005986Glyceraldehyde 3-PhosphateAdenosine Diphosphate inhibits the reaction [[GAPDH protein co-treated with NAD co-treated with Glyceraldehyde 3-Phosphate co-treated with Glutathione] results in increased reduction of sodium arsenite analog]15788719
D005986Glyceraldehyde 3-PhosphateAdenosine Triphosphate inhibits the reaction [[GAPDH protein co-treated with NAD co-treated with Glyceraldehyde 3-Phosphate co-treated with Glutathione] results in increased reduction of sodium arsenite analog]15788719
D005986Glyceraldehyde 3-Phosphate[GAPDH protein co-treated with NAD co-treated with Glyceraldehyde 3-Phosphate co-treated with Glutathione] results in increased reduction of sodium arsenite analog15788719
D005986Glyceraldehyde 3-Phosphate[Glyceraldehyde 3-Phosphate co-treated with NAD] inhibits the reaction [heptelidic acid results in decreased activity of GAPDH protein]15788719
D005986Glyceraldehyde 3-PhosphateGlyceraldehyde 3-Phosphate inhibits the reaction [heptelidic acid results in decreased activity of GAPDH protein]15788719
D005986Glyceraldehyde 3-Phosphateheptelidic acid inhibits the reaction [[GAPDH protein co-treated with NAD co-treated with Glyceraldehyde 3-Phosphate co-treated with Glutathione] results in increased reduction of sodium arsenite analog]15788719
D005986Glyceraldehyde 3-PhosphateNAD analog inhibits the reaction [[GAPDH protein co-treated with NAD co-treated with Glyceraldehyde 3-Phosphate co-treated with Glutathione] results in increased reduction of sodium arsenite analog]15788719
D005986Glyceraldehyde 3-PhosphateNADP inhibits the reaction [[GAPDH protein co-treated with NAD co-treated with Glyceraldehyde 3-Phosphate co-treated with Glutathione] results in increased reduction of sodium arsenite analog]15788719
D005986Glyceraldehyde 3-PhosphateGAPDH protein results in increased abundance of Glyceraldehyde 3-Phosphate11050244
C006253pirinixic acidpirinixic acid affects the expression of GAPDH mRNA19483382
D028321Plant PreparationsPlant Preparations affects the expression of GAPDH mRNA16046712|1625160
D011112Polymyxin BPolymyxin B inhibits the reaction [Alpha-Amanitin results in decreased expression of GAPDH mRNA]26385100
C027373potassium chromate(VI)potassium chromate(VI) results in decreased activity of GAPDH protein26582256
D011192Potassium DichromatePotassium Dichromate results in increased expression of GAPDH protein18563748
D011374ProgesteroneProgesterone results in decreased expression of GAPDH mRNA23018184
D011374ProgesteroneProgesterone results in increased expression of GAPDH mRNA16376865
D011398PromethazinePromethazine results in decreased expression of GAPDH mRNA28903497
D011441PropylthiouracilPropylthiouracil affects the expression of GAPDH mRNA19483382
D011441PropylthiouracilPropylthiouracil results in increased expression of GAPDH mRNA17403546
C100573prostaglandin A1prostaglandin A1 analog results in increased metabolism of GAPDH protein19800325
C030984pyrenepyrene results in decreased expression of GAPDH mRNA15963578
C020972pyrrolidine dithiocarbamic acidpyrrolidine dithiocarbamic acid results in increased expression of GAPDH mRNA11108245
D011794QuercetinQuercetin results in increased expression of GAPDH protein19207037
D011794QuercetinQuercetin results in increased oxidation of GAPDH protein17559999
D011794QuercetinQuercetin results in decreased expression of GAPDH protein18095365
C052785rebamipiderebamipide results in increased expression of GAPDH mRNA18299717
C059514resveratrolresveratrol affects the expression of GAPDH mRNA15748624
C059514resveratrolresveratrol binds to GAPDH protein24059224
C009166retinol acetateretinol acetate results in increased expression of GAPDH mRNA16772331
C089032rimonabantrimonabant results in increased expression of GAPDH mRNA16282221
C089730rosiglitazonerosiglitazone affects the expression of GAPDH protein19556978
D012402RotenoneGAPDH mutant form inhibits the reaction [Rotenone results in increased expression of and results in increased activity of CASP3 protein]25725130
D012402RotenoneGAPDH mutant form inhibits the reaction [Rotenone results in increased expression of TP53 protein]25725130
D012402RotenoneGAPDH mutant form promotes the reaction [Rotenone results in decreased expression of SQSTM1 protein]25725130
D012402RotenoneGAPDH mutant form promotes the reaction [Rotenone results in increased expression of ATG5 protein]25725130
D012402RotenoneGAPDH mutant form promotes the reaction [Rotenone results in increased expression of BECN1 protein]25725130
D012402RotenoneRotenone affects the localization of GAPDH protein19445904
D012402RotenoneRotenone promotes the reaction [GAPDH protein binds to GAPDH protein]19445904
D012402RotenoneRotenone results in decreased activity of GAPDH protein19445904|2173692
D012402RotenoneRotenone results in increased expression of and affects the localization of GAPDH protein21736921
D012402RotenoneRotenone results in increased expression of GAPDH mRNA19445904|2173692
D012402RotenoneRotenone results in increased expression of GAPDH protein19445904
C010327salinomycinsalinomycin results in decreased expression of GAPDH mRNA19682730
D012524SarinSarin results in decreased expression of GAPDH protein25842371
D012642SelegilineSelegiline inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of GAPDH mRNA]14724376
D012642SelegilineSelegiline inhibits the reaction [Hydroxyurea affects the localization of GAPDH protein]23696560
D012642SelegilineSelegiline inhibits the reaction [Paraquat affects the localization of GAPDH protein]20478973
D012643SeleniumSelenium results in increased expression of GAPDH mRNA19244175
D012643SeleniumSelenium inhibits the reaction [Paraquat results in decreased activity of GAPDH protein]17055214
D012822Silicon DioxideSilicon Dioxide analog results in increased secretion of GAPDH protein25895662
D019821SimvastatinSimvastatin results in decreased expression of GAPDH mRNA16414398
C080703SK&F 83959SK&F 83959 affects the expression of GAPDH protein25852303
C009277sodium arsenate[GAPDH protein co-treated with acetyl phosphate co-treated with NAD co-treated with Dithiothreitol] results in increased reduction of sodium arsenate analog19474219
C009277sodium arsenate[GAPDH protein co-treated with acetyl phosphate co-treated with NAD co-treated with Glutathione] results in increased reduction of sodium arsenate analog19474219
C009277sodium arsenate[GAPDH protein co-treated with acetyl phosphate co-treated with NAD co-treated with Mercaptoethanol] results in increased reduction of sodium arsenate analog19474219
C009277sodium arsenate[GAPDH protein co-treated with acetyl phosphate co-treated with NAD co-treated with Succimer] results in increased reduction of sodium arsenate analog19474219
C009277sodium arsenate[GAPDH protein co-treated with acetyl phosphate co-treated with NAD co-treated with Unithiol] results in increased reduction of sodium arsenate analog19474219
C009277sodium arsenate[GAPDH protein co-treated with Glutathione] results in increased reduction of sodium arsenate analog19478237
C009277sodium arsenate[[GAPDH protein co-treated with Glutathione] results in increased reduction of sodium arsenate analog] which results in increased chemical synthesis of arsenite19478237
C009277sodium arsenateheptelidic acid inhibits the reaction [[GAPDH protein co-treated with acetyl phosphate co-treated with NAD co-treated with Glutathione] results in increased reduction of sodium arsenate analog]19474219
C009277sodium arsenate[GAPDH protein co-treated with 3-phosphoglycerate co-treated with NAD] results in increased reduction of sodium arsenate analog15788719
C009277sodium arsenate"[GAPDH protein co-treated with fructose-1,6-diphosphate co-treated with NAD] results in increased reduction of sodium arsenate analog"15788719
C009277sodium arsenateheptelidic acid inhibits the reaction [[GAPDH protein co-treated with 3-phosphoglycerate co-treated with NAD] results in increased reduction of sodium arsenate analog]15788719
C009277sodium arsenate"heptelidic acid inhibits the reaction [[GAPDH protein co-treated with fructose-1,6-diphosphate co-treated with NAD] results in increased reduction of sodium arsenate analog]"15788719
C017947sodium arseniteAdenosine Diphosphate inhibits the reaction [[GAPDH protein co-treated with NAD co-treated with Glyceraldehyde 3-Phosphate co-treated with Glutathione] results in increased reduction of sodium arsenite analog]15788719
C017947sodium arseniteAdenosine Triphosphate inhibits the reaction [[GAPDH protein co-treated with NAD co-treated with Glyceraldehyde 3-Phosphate co-treated with Glutathione] results in increased reduction of sodium arsenite analog]15788719
C017947sodium arsenite[GAPDH protein co-treated with NAD co-treated with Glyceraldehyde 3-Phosphate co-treated with Glutathione] results in increased reduction of sodium arsenite analog15788719
C017947sodium arseniteNAD analog inhibits the reaction [[GAPDH protein co-treated with NAD co-treated with Glyceraldehyde 3-Phosphate co-treated with Glutathione] results in increased reduction of sodium arsenite analog]15788719
C017947sodium arseniteNADP inhibits the reaction [[GAPDH protein co-treated with NAD co-treated with Glyceraldehyde 3-Phosphate co-treated with Glutathione] results in increased reduction of sodium arsenite analog]15788719
C017947sodium arsenitesodium arsenite results in increased expression of GAPDH mRNA28713220
C017947sodium arsenitesodium arsenite results in increased expression of GAPDH protein15899475
C017947sodium arsenitesodium arsenite affects the expression of GAPDH mRNA17450228
C017947sodium arseniteAdenosine Diphosphate inhibits the reaction [[GAPDH protein co-treated with NAD co-treated with Glyceraldehyde 3-Phosphate co-treated with Glutathione] results in increased reduction of sodium arsenite analog]15788719
C017947sodium arseniteAdenosine Triphosphate inhibits the reaction [[GAPDH protein co-treated with NAD co-treated with Glyceraldehyde 3-Phosphate co-treated with Glutathione] results in increased reduction of sodium arsenite analog]15788719
C017947sodium arsenite[GAPDH protein co-treated with NAD co-treated with Glyceraldehyde 3-Phosphate co-treated with Glutathione] results in increased reduction of sodium arsenite analog15788719
C017947sodium arseniteheptelidic acid inhibits the reaction [[GAPDH protein co-treated with NAD co-treated with Glyceraldehyde 3-Phosphate co-treated with Glutathione] results in increased reduction of sodium arsenite analog]15788719
C017947sodium arseniteNAD analog inhibits the reaction [[GAPDH protein co-treated with NAD co-treated with Glyceraldehyde 3-Phosphate co-treated with Glutathione] results in increased reduction of sodium arsenite analog]15788719
C017947sodium arseniteNADP inhibits the reaction [[GAPDH protein co-treated with NAD co-treated with Glyceraldehyde 3-Phosphate co-treated with Glutathione] results in increased reduction of sodium arsenite analog]15788719
C017947sodium arsenite[sodium arsenite co-treated with Dithiothreitol] inhibits the reaction [Hydrogen Peroxide results in decreased activity of [GAPDH protein binds to GAPDH protein binds to GAPDH protein binds to GAPDH protein]]10403526
C017947sodium arsenite[sodium arsenite co-treated with Dithiothreitol] inhibits the reaction [Nitroprusside results in decreased activity of [GAPDH protein binds to GAPDH protein binds to GAPDH protein binds to GAPDH protein]]10403526
C017947sodium arsenite[sodium arsenite co-treated with Dithiothreitol] inhibits the reaction [S-Nitroso-N-Acetylpenicillamine results in decreased activity of [GAPDH protein binds to GAPDH protein binds to GAPDH protein binds to GAPDH protein]]10403526
C017947sodium arsenitesodium arsenite inhibits the reaction [S-Nitroso-N-Acetylpenicillamine results in increased metabolism of [GAPDH protein binds to GAPDH protein binds to GAPDH protein binds to GAPDH protein]]10403526
C017947sodium arsenite[GAPDH protein co-treated with 3-phosphoglycerate co-treated with NAD] results in increased chemical synthesis of sodium arsenite15788719
C017947sodium arsenite"[GAPDH protein co-treated with fructose-1,6-diphosphate co-treated with NAD] results in increased chemical synthesis of sodium arsenite"15788719
D017693Sodium Bicarbonate[Sodium Bicarbonate co-treated with Calcium Chloride] results in increased activity of GAPDH protein26582256
C016104sodium bichromatesodium bichromate results in increased expression of GAPDH mRNA12325037
C009282sodium cyanoborohydride"sodium cyanoborohydride affects the reaction [3,4-dihydroxyphenylacetaldehyde binds to and affects the metabolism of GAPDH protein]"19537779
D012967Sodium Dodecyl SulfateSodium Dodecyl Sulfate results in decreased expression of GAPDH mRNA12815608
D012969Sodium FluorideSodium Fluoride results in increased expression of GAPDH protein27548804
C538809sodium pentaboratesodium pentaborate results in decreased expression of GAPDH protein28285642
D004113Succimer[GAPDH protein co-treated with acetyl phosphate co-treated with NAD co-treated with Succimer] results in increased reduction of sodium arsenate analog19474219
D013434Sulfenic AcidsSulfenic Acids affects the reaction [Nitric Oxide results in decreased activity of GAPDH protein]10403526
D013481SuperoxidesCarbonyl Cyanide m-Chlorophenyl Hydrazone inhibits the reaction [[Glucose results in increased chemical synthesis of Superoxides] which results in decreased activity of GAPDH protein]11050244
D013481Superoxides[Glucose results in increased chemical synthesis of Superoxides] which results in decreased activity of GAPDH protein11050244
D013481Superoxidesmanganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [[Glucose results in increased chemical synthesis of Superoxides] which results in decreased activity of GAPDH protein]11050244
D013481SuperoxidesThenoyltrifluoroacetone inhibits the reaction [[Glucose results in increased chemical synthesis of Superoxides] which results in decreased activity of GAPDH protein]11050244
D013481SuperoxidesSOD2 protein inhibits the reaction [[Glucose results in increased chemical synthesis of Superoxides] which results in decreased activity of GAPDH protein]11050244
D013481SuperoxidesUCP1 protein inhibits the reaction [[Glucose results in increased chemical synthesis of Superoxides] which results in decreased activity of GAPDH protein]11050244
D013605T-2 ToxinT-2 Toxin affects the expression of GAPDH protein26141394
D013605T-2 ToxinT-2 Toxin results in decreased expression of GAPDH mRNA26141394
D013739TestosteroneTestosterone results in decreased expression of GAPDH mRNA21073676
D013739TestosteroneTestosterone results in decreased activity of GAPDH protein10650946
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased expression of GAPDH mRNA23152189
D013749TetrachlorodibenzodioxinAHR protein affects the reaction [Tetrachlorodibenzodioxin results in increased expression of GAPDH mRNA]19850099
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of GAPDH mRNA21570461
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased expression of GAPDH mRNA15667827|2468072
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased activity of GAPDH protein19850099
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of GAPDH mRNA19770486|1985009
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of GAPDH protein19850099
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased expression of GAPDH mRNA15703262
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of GAPDH mRNA16267337
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of GAPDH protein12361703
D013752TetracyclineTetracycline affects the expression of GAPDH mRNA25064622
C034269tetraethylenepentaminetetraethylenepentamine inhibits the reaction [cobaltous chloride results in increased expression of GAPDH mRNA]25100165
D0156472,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine"2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine affects the expression of GAPDH protein"25852303
C050950tetrakis(N-methyl-4-pyridiniumyl)porphine manganese(III) complextetrakis(N-methyl-4-pyridiniumyl)porphine manganese(III) complex inhibits the reaction [Ethanol results in decreased activity of GAPDH protein]28962519
C050950tetrakis(N-methyl-4-pyridiniumyl)porphine manganese(III) complextetrakis(N-methyl-4-pyridiniumyl)porphine manganese(III) complex inhibits the reaction [Ethanol results in decreased expression of GAPDH mRNA]28962519
D013804ThenoyltrifluoroacetoneThenoyltrifluoroacetone inhibits the reaction [[Glucose results in increased chemical synthesis of Superoxides] which results in decreased activity of GAPDH protein]11050244
D013853ThioacetamideThioacetamide affects the expression of GAPDH mRNA25064622
D013853ThioacetamideThioacetamide affects the expression of GAPDH mRNA19483382
D013853ThioacetamideThioacetamide results in decreased expression of GAPDH mRNA28903497
C009495titanium dioxidetitanium dioxide results in increased expression of GAPDH mRNA23131501
D014028Tobacco Smoke PollutionTobacco Smoke Pollution results in increased metabolism of GAPDH protein23396223
D014028Tobacco Smoke PollutionTobacco Smoke Pollution results in increased expression of GAPDH protein22595367
D014118Toxins, Biological"Toxins, Biological affects the expression of GAPDH mRNA"19682533
D014204Trenbolone AcetateTrenbolone Acetate results in decreased expression of GAPDH mRNA16488489
D014204Trenbolone AcetateTrenbolone Acetate affects the expression of GAPDH protein24072461
D014212TretinoinTretinoin results in decreased expression of GAPDH protein28886987
D014212TretinoinTretinoin results in increased expression of GAPDH mRNA24977338
C012589trichostatin Atrichostatin A results in decreased expression of GAPDH mRNA15901671
C012589trichostatin Atrichostatin A results in decreased expression of GAPDH protein19294695
C015559trimellitic anhydridetrimellitic anhydride results in increased expression of GAPDH mRNA19042947
D014303TrinitrotolueneTrinitrotoluene affects the expression of GAPDH mRNA21346803
C080163trovafloxacintrovafloxacin results in decreased expression of GAPDH mRNA24136188
C060213tryptamine-4,5-dione"[tryptamine-4,5-dione co-treated with Serotonin] affects the metabolism of and binds to GAPDH protein"23009681
D014494Unithiol[GAPDH protein co-treated with acetyl phosphate co-treated with NAD co-treated with Unithiol] results in increased reduction of sodium arsenate analog19474219
D014635Valproic AcidValproic Acid affects the expression of GAPDH mRNA25064622
D014635Valproic AcidValproic Acid results in decreased expression of GAPDH mRNA15901671
D001335Vehicle EmissionsVehicle Emissions results in decreased methylation of GAPDH gene25560391
C025643vinclozolinvinclozolin affects the expression of GAPDH mRNA19015723
D014810Vitamin EVitamin E results in increased expression of GAPDH mRNA19244175
D015032ZincGAPDH protein binds to Zinc14534351
D015032ZincZinc results in decreased activity of GAPDH protein12798935
D015032ZincZinc results in decreased activity of GAPDH protein12798935

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0004365glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity-EXP3170585  7144574  
GO:0004365glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity-IBA21873635  
GO:0004365glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity-ISS-  
GO:0004365glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity-NAS3170585  7030790  
GO:0005515protein binding-IPI11724794  15628863  16169070  16799092  17540579  20029029  
20392205  20849852  21044950  23348613  23355646  23823123  
24658140  25417112  
GO:0008017microtubule binding-ISS-  
GO:0019828aspartic-type endopeptidase inhibitor activity-IDA22832495  
GO:0035605peptidyl-cysteine S-nitrosylase activity-ISS-  
GO:0042802identical protein binding-IPI20392205  21988832  
GO:0050661NADP binding-IEA-  
GO:0051287NAD binding-IEA-  
GO:0097718disordered domain specific binding-IPI11785981  
GO ID GO Term Qualifier Evidence PubMed
GO:0000226microtubule cytoskeleton organization-ISS-  
GO:0006094gluconeogenesis-TAS-  
GO:0006096glycolytic process-IBA21873635  
GO:0010951negative regulation of endopeptidase activity-IDA22832495  
GO:0016241regulation of macroautophagy-TAS26626483  
GO:0017148negative regulation of translation-IDA23071094  
GO:0017148negative regulation of translation-IMP15479637  
GO:0031640killing of cells of other organism-IDA22832495  
GO:0035606peptidyl-cysteine S-trans-nitrosylation-ISS-  
GO:0050715positive regulation of cytokine secretion-IDA22832495  
GO:0050821protein stabilization-ISS-  
GO:0050832defense response to fungus-IDA22832495  
GO:0051402neuron apoptotic process-ISS-  
GO:0051873killing by host of symbiont cells-IDA22832495  
GO:0052501positive regulation by organism of apoptotic process in other organism involved in symbiotic interaction-IDA22832495  
GO:0061621canonical glycolysis-TAS-  
GO:0061844antimicrobial humoral immune response mediated by antimicrobial peptide-IDA22832495  
GO:0071346cellular response to interferon-gamma-IDA15479637  
GO ID GO Term Qualifier Evidence PubMed
GO:0005634nucleus-HDA21630459  
GO:0005634nucleus-ISS-  
GO:0005737cytoplasm-IDA11785981  24507776  
GO:0005737cytoplasm-ISS-  
GO:0005811lipid droplet-IDA14741744  
GO:0005829cytosol-IBA21873635  
GO:0005829cytosol-IDA24101517  
GO:0005829cytosol-ISS-  
GO:0005829cytosol-TAS-  
GO:0005886plasma membrane-IDA-  
GO:0015630microtubule cytoskeleton-ISS-  
GO:0016020membrane-HDA19946888  
GO:0031965nuclear membrane-IDA-  
GO:0031982vesicle-HDA19190083  
GO:0043231intracellular membrane-bounded organelle-IDA-  
GO:0048471perinuclear region of cytoplasm-IEA-  
GO:0070062extracellular exosome-HDA11487543  12519789  19056867  19199708  20458337  21362503  23533145  
GO:0097452GAIT complex-IDA15479637  23071094  
GO:1990904ribonucleoprotein complex-IDA15479637  
KEGG ID KEGG Term
hsa00010Glycolysis / Gluconeogenesis
hsa01100Metabolic pathways
hsa05010Alzheimer's disease
Reactome ID Reactome Term Evidence
R-HSA-1430728MetabolismTAS
R-HSA-70171GlycolysisTAS
R-HSA-70263GluconeogenesisTAS
R-HSA-70326Glucose metabolismTAS
R-HSA-71387Metabolism of carbohydratesTAS

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
17164495The effects of long-term smoking on endothelial nitric oxide synthase mRNA expression in human platelets as detected with real-time quantitative RT-PCR. (2007 Jan)Shimasaki YClin Appl Thromb Hemost
26022259Nitric Oxide-GAPDH Transcriptional Signaling Mediates Behavioral Actions of Cocaine. (2015)Harraz MMCNS Neurol Disord Drug Targets
16800968Decreased fragile histidine triad gene messenger RNA expression in lung cancer. (2006 May)Sasaki HClin Lung Cancer
12765978Genotype-specific influence on nitric oxide synthase gene expression, protein concentrations, and enzyme activity in cultured human endothelial cells. (2003 Jun)Song JClin Chem
22885022Gene expression of human beta defensins-1 and -2 is significantly reduced in non-inflamed keratinized oral tissue of smokers. (2012 Nov)Wolgin MJ Dent
12140138Expression of estrogen receptors alpha and beta in human lung tissue and cell lines. (2002 Aug)Mollerup SLung Cancer
15364129Expression of LUN gene that encodes a novel RING finger protein is correlated with development and progression of non-small cell lung cancer. (2004 Oct)Oyanagi HLung Cancer
24120969Comparative reactivity of the myeloperoxidase-derived oxidants hypochlorous acid and hypothiocyanous acid with human coronary artery endothelial cells. (2013 Dec)Lloyd MMFree Radic Biol Med
10223202Decreased expression of glutathione S-transferase M1 in HPV16-transfected human cervical keratinocytes in culture. (1999 Apr)Chen CCarcinogenesis
19283474Cortical NMDA receptor expression in human chronic alcoholism: influence of the TaqIA allele of ANKK1. (2009 Oct)Ridge JPNeurochem Res
24824616A comprehensive approach to identify reliable reference gene candidates to investigate the link between alcoholism and endocrinology in Sprague-Dawley rats. (2014)Taki FAPLoS One
23064950Short-term cigarette smoke exposure induces reversible changes in energy metabolism and cellular redox status independent of inflammatory responses in mouse lungs. (2012 Nov 15)Agarwal ARAm J Physiol Lung Cell Mol Physiol
22890201Monoamine oxidases in major depressive disorder and alcoholism. (2012 Jun)Duncan JDrug Discov Ther
28513228Relationship between CHOP/GADD153 and unstable human carotid atherosclerotic plaque. (2017 Dec)Wang SBr J Neurosurg
20022592A novel role for glyceraldehyde-3-phosphate dehydrogenase and monoamine oxidase B cascade in ethanol-induced cellular damage. (2010 May 1)Ou XMBiol Psychiatry
18671841PSMB2 and RPL32 are suitable denominators to normalize gene expression profiles in bronchoalveolar cells. (2008 Jul 31)Kriegova EBMC Mol Biol
18260159Smoking in pregnancy is associated with increased total maternal serum cell-free DNA levels. (2008 Mar)Urato ACPrenat Diagn
18055732Maternal smoking: effect on circulating cell-free fetal and total DNA levels in maternal plasma from the second trimester. (2007 Dec)Lapaire OObstet Gynecol
20204567Ethanol increases TIEG2-MAO B cell death cascade in the prefrontal cortex of ethanol-preferring rats. (2011 May)Ou XMNeurotox Res
24101392Human endothelial lecitin-like oxLDL receptor-1 (LOX-1) expression is not associated with impairment of endothelium-dependent vasoreactivity in conduit vessels. (2013 Aug)Wetterau EJ Physiol Pharmacol
28508372Effect of Second-Hand Tobacco Smoke on the Nitration of Brain Proteins: A Systems Biology and Bioinformatics Approach. (2017)Kobeissy FHMethods Mol Biol
17922974CCND1 messenger RNA expression is correlated with EGFR mutation status in lung cancer. (2007 Sep)Sasaki HClin Lung Cancer
28959653p-Benzoquinone initiates non-invasive urothelial cancer through aberrant tyrosine phosphorylation of EGFR, MAP kinase activation and cell cycle deregulation: Prevention by vitamin C. (2017)Ganguly SToxicol Rep
23994029Hydroquinone induces oxidative and mitochondrial damage to human retinal Muller cells (MIO-M1). (2013 Dec)Ramirez CNeurotoxicology
23792774The effects of acetaldehyde and acrolein on muscle catabolism in C2 myotubes. (2013 Dec)Rom OFree Radic Biol Med
9596562Expression of GABA(A) receptor isoform genes in the cerebral cortex of cirrhotic and alcoholic cases assessed by S1 nuclease protection assays. (1998 Apr)Thomas GJNeurochem Int
11289356Matrix metalloproteinase-1 and skin ageing in smokers. (2001 Mar 24)Lahmann CLancet
24151387No evidence of HPV DNA in esophageal squamous cell carcinoma in a population of Southern Brazil. (2013 Oct 21)Antunes LCWorld J Gastroenterol
12876071Acute and chronic effects of alcohol exposure on skeletal muscle c-myc, p53, and Bcl-2 mRNA expression. (2003 Dec)Nakahara TAm J Physiol Endocrinol Metab
22932142[Expressions and clinical significance of high mobility group box-1 mRNA and protein in laryngeal squamous cell carcinoma tissues and serum]. (2012 Jun)Guo YZhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi