Gene: RIBC2

26150
C22orf11|TRIB
RIB43A domain with coiled-coils 2
protein-coding
22q13.31
Ensembl:ENSG00000128408 Vega:OTTHUMG00000151332 UniprotKB:Q9H4K1
NC_000022.11
SNP Mapped
1   ANCO-SNPs
AD
0   
8.092e-2 (AD)  7.151e-1 (ND)   (Frontal_Cortex)
1.875e-1 (AD)  4.234e-1 (ND)

ANCO-SNPs

SNP ID Position Alleles Trait Variation Type
rs9614466chr22:45415482 (GRCh38.p7)A>Galcohol dependenceSNV(Single Nucleotide Variation)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
BBS120.596
SIMC10.592
EXO50.591
ZDHHC150.578
CLGN0.578
UBE3D0.573
ORC50.573
CCNB10.572
CEP190.571
TTC39A0.571

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
DIO2-0.301
MAPKAPK3-0.3
VNN3-0.293
ENDOU-0.286
LRAT-0.278
HOXD8-0.275
MBNL3-0.271
C5orf64-0.269
TIGIT-0.268
RBP1-0.268

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C0065512-amino-2-methyl-1-propanol2-amino-2-methyl-1-propanol results in decreased expression of RIBC2 mRNA25088246
D000082AcetaminophenAcetaminophen results in increased expression of RIBC2 mRNA22230336
D016604Aflatoxin B1Aflatoxin B1 results in increased expression of RIBC2 mRNA22100608
D000535Aluminum[APP protein modified form binds to Aluminum] which results in decreased expression of RIBC2 mRNA21298039
C006780bisphenol Abisphenol A affects the expression of RIBC2 mRNA20170705
C006780bisphenol Abisphenol A results in decreased expression of RIBC2 mRNA25181051
D019327Copper SulfateCopper Sulfate results in decreased expression of RIBC2 mRNA19549813
D003375Coumestrol[Coumestrol co-treated with resveratrol] results in increased expression of RIBC2 mRNA19167446
D003471CuprizoneCuprizone results in increased expression of RIBC2 mRNA26577399
D002945CisplatinCisplatin results in increased expression of RIBC2 mRNA27594783
D004726Endosulfan[Endosulfan co-treated with Tetrachlorodibenzodioxin] results in increased expression of RIBC2 mRNA26159488
D004997Ethinyl EstradiolEthinyl Estradiol results in increased expression of RIBC2 mRNA17942748
D004997Ethinyl Estradiol[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of RIBC2 mRNA17942748
D015025ZearalenoneZearalenone results in decreased expression of RIBC2 mRNA19371625
C561695(+)-JQ1 compound(+)-JQ1 compound results in decreased expression of RIBC2 mRNA24796395
C017461lead nitratelead nitrate results in decreased expression of RIBC2 mRNA21628963
D010100OxygenOxygen deficiency results in decreased expression of RIBC2 mRNA26516004
C059514resveratrol[Coumestrol co-treated with resveratrol] results in increased expression of RIBC2 mRNA19167446
C017947sodium arsenitesodium arsenite affects the methylation of RIBC2 gene28589171
C017947sodium arsenitesodium arsenite results in decreased expression of and affects the splicing of RIBC2 mRNA25879800
C017947sodium arsenitesodium arsenite results in increased expression of RIBC2 mRNA28595984
D013749Tetrachlorodibenzodioxin[Endosulfan co-treated with Tetrachlorodibenzodioxin] results in increased expression of RIBC2 mRNA26159488
D013749Tetrachlorodibenzodioxin[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of RIBC2 mRNA17942748
C016805tris(1,3-dichloro-2-propyl)phosphate"tris(1,3-dichloro-2-propyl)phosphate results in decreased expression of RIBC2 mRNA"26179874
D014520UrethaneUrethane results in decreased expression of RIBC2 mRNA28818685
D024483Vitamin K 3Vitamin K 3 affects the expression of RIBC2 mRNA20044591

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0005515protein binding-IPI22458338  
GO ID GO Term Qualifier Evidence PubMed
GO ID GO Term Qualifier Evidence PubMed
GO:0005634nucleus-HDA21630459  
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal