Gene: GATA3

2625
HDR|HDRS
GATA binding protein 3
protein-coding
10p14
Ensembl:ENSG00000107485 MIM:131320 Vega:OTTHUMG00000017640 UniprotKB:P23771
NG_015859.1
PubMed
ND
10   
NA (AD)  NA (ND)   (Frontal_Cortex)
8.095e-1 (AD)  9.269e-1 (ND)

DNA Methylation

Probe Locus(GRCh37) Gene Region p-val Trait PubMed ID
cg11679455chr10:8100761GATA33.700e-10Smoking27651444
cg22770911chr10:8101307GATA37.530e-9Smoking28686328

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
LUM0.745
DSC30.736
GPX80.723
SIX10.719
DSP0.711
ASPN0.705
PDE5A0.699
PRG40.692
TP630.688
SLPI0.685

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
ZNF835-0.445
RNFT2-0.438
MYADML2-0.432
FEZF2-0.416
KSR2-0.414
CELSR2-0.412
BCL11A-0.411
MAGIX-0.41
CHRNA4-0.41
FAM171A2-0.409

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C559381((1-ethylpyrrolidin-2-yl) methyl)-4-hydroxy-7-methoxy-quinoline-3-carboxamide((1-ethylpyrrolidin-2-yl) methyl)-4-hydroxy-7-methoxy-quinoline-3-carboxamide results in decreased expression of GATA3 mRNA21195814
C0297902,2',3',4,4',5-hexachlorobiphenyl"[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in increased expression of GATA3 mRNA"25510870
C0817662,4,4'-trichlorobiphenyl"[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in increased expression of GATA3 mRNA"25510870
C0140242,4,5,2',4',5'-hexachlorobiphenyl"[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in increased expression of GATA3 mRNA"25510870
C0098282,4,5,2',5'-pentachlorobiphenyl"[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in increased expression of GATA3 mRNA"25510870
C0094072,5,2',5'-tetrachlorobiphenyl"[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in increased expression of GATA3 mRNA"25510870
C5850042-monochloropropanediol2-monochloropropanediol results in increased expression of GATA3 mRNA28522335
C0188552-tert-butylhydroquinone[2-tert-butylhydroquinone results in increased activity of NFE2L2 protein] which results in increased activity of GATA3 protein22250088
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with belinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of GATA3 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with entinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of GATA3 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with mercuric bromide co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of GATA3 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with panobinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of GATA3 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of GATA3 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of GATA3 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of GATA3 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of GATA3 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with vorinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of GATA3 mRNA"27188386
C0275764-hydroxy-2-nonenal4-hydroxy-2-nonenal results in decreased expression of GATA3 mRNA12419474
C0275764-hydroxy-2-nonenal4-hydroxy-2-nonenal results in decreased expression of GATA3 mRNA19191707
C0165834-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased activity of GATA3 protein16835749
C0165834-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of GATA3 mRNA16582591|1683574
C0165834-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanoneBungarotoxins inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased activity of GATA3 protein]16835749
C0165834-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanoneMecamylamine inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased activity of GATA3 protein]16835749
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with belinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of GATA3 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with entinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of GATA3 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with mercuric bromide co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of GATA3 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with panobinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of GATA3 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of GATA3 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of GATA3 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of GATA3 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of GATA3 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with vorinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of GATA3 mRNA"27188386
C1118556-formylindolo(3,2-b)carbazole"6-formylindolo(3,2-b)carbazole results in decreased expression of GATA3"22561122
D000082AcetaminophenAcetaminophen affects the expression of GATA3 mRNA17562736
D016604Aflatoxin B1Aflatoxin B1 results in decreased methylation of GATA3 gene27153756
C430898AGN 194204AGN 194204 results in increased expression of GATA3 mRNA11970994|1633952
D000395Air Pollutants, Occupational"Air Pollutants, Occupational results in increased expression of GATA3 mRNA"23195993
D000643Ammonium ChlorideAmmonium Chloride affects the expression of GATA3 mRNA16483693
D039741Antigens, Dermatophagoides"GATA3 protein affects the reaction [[Particulate Matter co-treated with Antigens, Dermatophagoides] results in increased expression of IL13 protein]"27315767
D039741Antigens, Dermatophagoides"GATA3 protein affects the reaction [[Vehicle Emissions co-treated with Antigens, Dermatophagoides] results in increased expression of IL13 protein]"27315767
C000228aristolochic acid I[aristolochic acid I co-treated with aristolochic acid II] results in decreased expression of GATA3 mRNA23912714
C042310aristolochic acid II[aristolochic acid I co-treated with aristolochic acid II] results in decreased expression of GATA3 mRNA23912714
C006632arsenic trioxidearsenic trioxide inhibits the reaction [GATA3 protein binds to IL13 promoter]19080345
C006632arsenic trioxidearsenic trioxide inhibits the reaction [GATA3 protein binds to KPNA2 protein]19080345
C015001arsenitearsenite results in increased methylation of GATA3 promoter23974009
C487081belinostatbelinostat results in increased expression of GATA3 mRNA26272509
C487081belinostat"[NOG protein co-treated with belinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of GATA3 mRNA"27188386
C006703benzo(b)fluoranthenebenzo(b)fluoranthene results in decreased expression of GATA3 mRNA26377693
D019324beta-Naphthoflavone[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of GATA3 mRNA18164116
D001564Benzo(a)pyreneBenzo(a)pyrene results in decreased expression of GATA3 mRNA21569818
D001564Benzo(a)pyreneBenzo(a)pyrene results in decreased expression of GATA3 mRNA22300585
D0151237,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide"7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of GATA3 mRNA"17944540
D004958EstradiolEstradiol results in increased expression of GATA3 mRNA19484750
C002791bismuth tripotassium dicitratebismuth tripotassium dicitrate results in decreased expression of GATA3 mRNA15912405
C006780bisphenol Abisphenol A results in decreased expression of GATA3 mRNA26363213
C006780bisphenol Abisphenol A affects the methylation of GATA3 promoter27334623
C006780bisphenol Abisphenol A results in increased expression of GATA3 protein20553123|2774367
C006780bisphenol APhytochemicals inhibits the reaction [bisphenol A results in increased expression of GATA3 protein]20553123
C006780bisphenol A[bisphenol A co-treated with Testosterone] results in decreased expression of GATA3 mRNA26496021
C006780bisphenol Abisphenol A results in decreased expression of GATA3 mRNA25181051
C005961bis(tri-n-butyltin)oxidebis(tri-n-butyltin)oxide results in increased expression of GATA3 mRNA17553608
D001761BleomycinBleomycin results in increased expression of GATA3 mRNA29033951
D001761BleomycinS1PR5 protein affects the reaction [Bleomycin results in increased expression of GATA3 mRNA]29033951
D002038BungarotoxinsBungarotoxins inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased activity of GATA3 protein]16835749
D002038BungarotoxinsBungarotoxins inhibits the reaction [N'-nitrosonornicotine results in increased activity of GATA3 protein]16835749
D002038BungarotoxinsBungarotoxins inhibits the reaction [N'-nitrosonornicotine results in increased expression of GATA3 mRNA]16835749
D019328Buthionine Sulfoximine[Methimazole co-treated with Buthionine Sulfoximine] results in increased expression of GATA3 mRNA22407903|2742157
D019328Buthionine Sulfoximine[Phenytoin co-treated with Buthionine Sulfoximine] results in decreased expression of GATA3 mRNA23986454
D019328Buthionine SulfoximineButhionine Sulfoximine results in decreased expression of GATA3 mRNA26177832
D002220CarbamazepineCarbamazepine affects the expression of GATA3 mRNA25979313
D002273CarcinogensCarcinogens results in increased expression of GATA3 mRNA16316942
D020245p-Chloromercuribenzoic Acid"[NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of GATA3 mRNA"27188386
D020245p-Chloromercuribenzoic Acidp-Chloromercuribenzoic Acid results in increased expression of GATA3 mRNA26272509
D002737ChloropreneChloroprene results in decreased expression of GATA3 mRNA23125180
D002794Choline[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of GATA3 gene20938992
C561036clodinafop-propargylclodinafop-propargyl results in decreased expression of GATA321495064
C018021cobaltous chloridecobaltous chloride results in increased expression of GATA3 mRNA24386269
D003375CoumestrolCoumestrol results in decreased expression of GATA3 mRNA19167446
D003520CyclophosphamideCyclophosphamide results in decreased expression of GATA3 mRNA21041162
C556733dechlorane 602dechlorane 602 results in increased expression of GATA3 mRNA27081854
C014347decitabine[decitabine co-treated with trichostatin A] results in decreased expression of GATA3 mRNA17891453
D013759DronabinolDronabinol results in increased expression of GATA3 mRNA16434616|1704100
D013759DronabinolGATA3 affects the reaction [Dronabinol results in increased expression of OPRM1 mRNA]16434616
D013759DronabinolIL4 protein mutant form inhibits the reaction [Dronabinol results in increased expression of GATA3 mRNA]16434616
D013759DronabinolSTAT5A affects the reaction [Dronabinol results in increased expression of GATA3 mRNA]16434616
D013759DronabinolSTAT6 affects the reaction [Dronabinol results in increased expression of GATA3 mRNA]16434616
D013759DronabinolDronabinol results in increased expression of GATA3 mRNA14741435
D013759DronabinolSR 144528 inhibits the reaction [Dronabinol results in increased expression of GATA3 mRNA]14741435
D003907DexamethasoneDexamethasone results in decreased expression of GATA3 mRNA21041162
D002945Cisplatin[Cisplatin co-treated with jinfukang] results in decreased expression of GATA3 mRNA27392435
D004041Dietary FatsDietary Fats results in increased expression of GATA3 mRNA22010203
D004041Dietary FatsTestosterone inhibits the reaction [Dietary Fats results in increased expression of GATA3 mRNA]22010203
D004041Dietary FatsDietary Fats results in decreased expression of GATA3 mRNA21852083
D004041Dietary Fatsresveratrol inhibits the reaction [Dietary Fats results in decreased expression of GATA3 mRNA]21852083
D004051Diethylhexyl PhthalateDiethylhexyl Phthalate results in increased expression of GATA3 mRNA28286118
D004052Diethylnitrosamine[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of GATA3 mRNA18164116
D004054DiethylstilbestrolDiethylstilbestrol results in decreased expression of GATA3 mRNA21041162
D002117CalcitriolCalcitriol results in increased expression of GATA3 mRNA26485663
D004237DiuronDiuron results in decreased expression of GATA3 mRNA21551480
D004391DustDust results in increased expression of GATA3 mRNA17805423
C118739entinostatentinostat results in increased expression of GATA3 mRNA26272509
C118739entinostat"[NOG protein co-treated with entinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of GATA3 mRNA"27188386
D000431EthanolEthanol results in increased expression of GATA3 protein19428696
C018063ethyl protocatechuateethyl protocatechuate inhibits the reaction [rosiglitazone results in increased ubiquitination of and results in increased degradation of GATA3 protein]24338020
D005492Folic Acid[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of GATA3 gene20938992
D015248GemfibrozilGemfibrozil results in decreased expression of GATA3 mRNA20006695
D005839GentamicinsGentamicins results in increased expression of GATA3 mRNA22061828
D006861Hydrogen PeroxideHydrogen Peroxide affects the expression of GATA3 mRNA20044591
D007052IbuprofenIbuprofen results in decreased expression of GATA3 mRNA17630191
D015759Ionomycin[PSMB8 protein co-treated with PSMB10 protein] affects the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of GATA3 mRNA]22398747
D015759Ionomycin[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of GATA3 mRNA22398747
C051890irinotecanirinotecan metabolite results in decreased expression of GATA3 mRNA15956246
C051890irinotecanirinotecan results in decreased expression of GATA3 mRNA15956246
C544151jinfukang[Cisplatin co-treated with jinfukang] results in decreased expression of GATA3 mRNA27392435
C544151jinfukangjinfukang results in decreased expression of GATA3 mRNA27392435
C561695(+)-JQ1 compoundGATA3 mutant form results in increased susceptibility to (+)-JQ1 compound24874954
C561695(+)-JQ1 compound(+)-JQ1 compound results in increased expression of GATA3 mRNA24874954
D007840LatexLatex analog results in increased expression of GATA3 mRNA24768652
C008261lead acetatelead acetate results in decreased expression of GATA3 mRNA22613225
D001556LindaneLindane results in increased expression of GATA3 mRNA24356939
D008464MecamylamineMecamylamine inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased activity of GATA3 protein]16835749
D008464MecamylamineMecamylamine inhibits the reaction [N'-nitrosonornicotine results in increased activity of GATA3 protein]16835749
D008464MecamylamineMecamylamine inhibits the reaction [N'-nitrosonornicotine results in increased expression of GATA3 mRNA]16835749
C042720mercuric bromidemercuric bromide results in increased expression of GATA3 mRNA26272509
C042720mercuric bromide"[NOG protein co-treated with mercuric bromide co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of GATA3 mRNA"27188386
D008713Methimazole[Methimazole co-treated with Buthionine Sulfoximine] results in increased expression of GATA3 mRNA22407903|2742157
D008713MethimazoleMethimazole results in increased expression of GATA3 mRNA22407903|2617783
D008713MethimazoleMethimazole results in decreased expression of GATA3 mRNA22504374
D008715Methionine[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of GATA3 gene20938992
D008727MethotrexateMethotrexate results in increased expression of GATA3 mRNA17400583
C004925methylmercuric chloridemethylmercuric chloride results in decreased expression of GATA3 mRNA23179753
C004925methylmercuric chloridemethylmercuric chloride results in increased expression of GATA3 mRNA28001369
D008767Methylmercury CompoundsMethylmercury Compounds results in increased expression of GATA3 mRNA21664453
D0156551-Methyl-4-phenylpyridinium1-Methyl-4-phenylpyridinium results in decreased expression of GATA3 mRNA27037955
D037742Nanotubes, Carbon"Nanotubes, Carbon analog results in decreased expression of GATA3 mRNA"25554681
D037742Nanotubes, Carbon"Nanotubes, Carbon results in decreased expression of GATA3 mRNA"25554681
D037742Nanotubes, Carbon"Nanotubes, Carbon results in increased expression of GATA3 protein"27106021
D0150581-Naphthylisothiocyanate1-Naphthylisothiocyanate affects the expression of GATA3 mRNA20594950
D009532NickelNickel results in decreased expression of GATA3 mRNA24768652
D009532NickelNickel results in increased expression of GATA3 mRNA23195993
C028007nickel monoxidenickel monoxide results in increased expression of GATA3 mRNA27464988
C028007nickel monoxidenickel monoxide results in increased expression of GATA3 protein27464988
C008655N'-nitrosonornicotineBungarotoxins inhibits the reaction [N'-nitrosonornicotine results in increased activity of GATA3 protein]16835749
C008655N'-nitrosonornicotineBungarotoxins inhibits the reaction [N'-nitrosonornicotine results in increased expression of GATA3 mRNA]16835749
C008655N'-nitrosonornicotineMecamylamine inhibits the reaction [N'-nitrosonornicotine results in increased activity of GATA3 protein]16835749
C008655N'-nitrosonornicotineMecamylamine inhibits the reaction [N'-nitrosonornicotine results in increased expression of GATA3 mRNA]16835749
C008655N'-nitrosonornicotineN'-nitrosonornicotine results in increased activity of GATA3 protein16835749
C008655N'-nitrosonornicotineN'-nitrosonornicotine results in increased expression of GATA3 mRNA16582591|1683574
D010047OvalbuminOvalbumin results in increased expression of GATA3 mRNA28344896
C030110oxaliplatin[oxaliplatin co-treated with Topotecan] results in increased expression of GATA3 mRNA25729387
D010126OzoneOzone results in decreased expression of GATA3 mRNA17460151
C496932panobinostat"[NOG protein co-treated with panobinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of GATA3 mRNA"27188386
C496932panobinostatpanobinostat results in increased expression of GATA3 mRNA26272509
D010269ParaquatParaquat results in decreased expression of GATA325496228
D052638Particulate Matter"GATA3 protein affects the reaction [[Particulate Matter co-treated with Antigens, Dermatophagoides] results in increased expression of IL13 protein]"27315767
D052638Particulate MatterParticulate Matter results in increased expression of GATA3 mRNA23416701
D052638Particulate MatterParticulate Matter results in increased expression of GATA3 mRNA22134058
C410127PCB 180"[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in increased expression of GATA3 mRNA"25510870
D010476PerfumePerfume results in increased expression of GATA3 mRNA24768652
D010662Phenylmercuric Acetate"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of GATA3 mRNA"27188386
D010662Phenylmercuric AcetatePhenylmercuric Acetate results in increased expression of GATA3 mRNA26272509
D010672Phenytoin[Phenytoin co-treated with Buthionine Sulfoximine] results in decreased expression of GATA3 mRNA23986454
D010672PhenytoinPhenytoin results in decreased expression of GATA3 mRNA23986454
D064209PhytochemicalsPhytochemicals inhibits the reaction [bisphenol A results in increased expression of GATA3 protein]20553123
C006253pirinixic acid[pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of GATA3 mRNA19710929
D010936Plant ExtractsPlant Extracts results in decreased expression of GATA3 mRNA20580249
D028321Plant PreparationsPlant Preparations results in decreased expression of GATA3 protein15330010
D011189Potassium ChloridePotassium Chloride results in increased expression of GATA3 mRNA21624428
D011441PropylthiouracilPropylthiouracil results in decreased expression of GATA3 mRNA22504374
C004532quinonequinone results in increased expression of GATA3 mRNA28986286
C059514resveratrolresveratrol results in decreased expression of GATA3 mRNA22962611
C059514resveratrolresveratrol inhibits the reaction [Dietary Fats results in decreased expression of GATA3 mRNA]21852083
D015474Isotretinoin[vorinostat co-treated with Isotretinoin] results in increased expression of GATA3 mRNA18769122
C116926rofecoxibrofecoxib results in decreased expression of GATA3 mRNA17070997
C045282roquinimexroquinimex results in decreased expression of GATA3 mRNA21195814
C089730rosiglitazoneethyl protocatechuate inhibits the reaction [rosiglitazone results in increased ubiquitination of and results in increased degradation of GATA3 protein]24338020
C089730rosiglitazonerosiglitazone results in increased ubiquitination of and results in increased degradation of GATA3 protein24338020
D012906SmokeSmoke results in decreased expression of GATA3 mRNA21095227
C017947sodium arsenitesodium arsenite affects the methylation of GATA3 gene28589171
C017947sodium arsenitesodium arsenite results in decreased expression of GATA3 mRNA12634122|2549360
C017947sodium arsenitesodium arsenite results in increased stability of GATA3 mRNA25493608
C017947sodium arsenitesodium arsenite results in increased expression of GATA3 mRNA28843991
D018038Sodium SeleniteSodium Selenite results in increased expression of GATA3 mRNA18175754
D053260SootSoot results in decreased expression of GATA3 mRNA26551751
C110630SR 144528SR 144528 inhibits the reaction [Dronabinol results in increased expression of GATA3 mRNA]14741435
D013619TacrineTacrine results in increased expression of GATA3 mRNA12832660
D013629TamoxifenESR1 protein affects the reaction [GATA3 protein affects the susceptibility to Tamoxifen]19084267
D013629TamoxifenTamoxifen results in increased expression of GATA3 mRNA19031437
D013739TestosteroneTestosterone inhibits the reaction [Dietary Fats results in increased expression of GATA3 mRNA]22010203
D013739Testosterone[bisphenol A co-treated with Testosterone] results in decreased expression of GATA3 mRNA26496021
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of GATA3 mRNA26377647
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of GATA3 mRNA18684927|2405805
D013755Tetradecanoylphorbol Acetate[PSMB8 protein co-treated with PSMB10 protein] affects the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of GATA3 mRNA]22398747
D013755Tetradecanoylphorbol Acetate[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of GATA3 mRNA22398747
D013792ThalidomideThalidomide results in increased expression of GATA3 protein19428696
D013893ThiramThiram results in increased expression of GATA3 mRNA20530235
C009495titanium dioxidetitanium dioxide results in decreased expression of GATA3 mRNA23409001|2776080
D014028Tobacco Smoke PollutionTobacco Smoke Pollution results in decreased methylation of GATA3 gene26756918
D014050TolueneToluene affects the expression of GATA3 mRNA21601613
D014050TolueneToluene results in decreased expression of GATA3 mRNA19571489
D019772Topotecan[oxaliplatin co-treated with Topotecan] results in increased expression of GATA3 mRNA25729387
D019772TopotecanTopotecan results in increased expression of GATA3 mRNA25729387
D014118Toxins, Biological"Toxins, Biological affects the expression of GATA3 mRNA"19682533
D014212TretinoinTretinoin results in increased expression of GATA3 mRNA17118196|1713896
C012589trichostatin A[decitabine co-treated with trichostatin A] results in decreased expression of GATA3 mRNA17891453
C012589trichostatin A"[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of GATA3 mRNA"27188386
C012589trichostatin Atrichostatin A results in increased expression of GATA3 mRNA24935251|2627250
C015559trimellitic anhydridetrimellitic anhydride results in increased expression of GATA3 mRNA19042947|2021965
D014635Valproic Acid"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of GATA3 mRNA"27188386
D014635Valproic AcidValproic Acid results in increased expression of GATA3 mRNA23179753|2438349
D014635Valproic AcidValproic Acid results in increased methylation of GATA3 gene29154799
D014635Valproic AcidValproic Acid affects the expression of GATA3 mRNA17292431
D014635Valproic AcidValproic Acid results in decreased expression of GATA3 mRNA24896083
D014635Valproic AcidValproic Acid results in increased expression of GATA3 protein19428696
D014638VanadatesVanadates results in increased expression of GATA3 mRNA22714537
D001335Vehicle Emissions"GATA3 protein affects the reaction [[Vehicle Emissions co-treated with Antigens, Dermatophagoides] results in increased expression of IL13 protein]"27315767
D001335Vehicle EmissionsVehicle Emissions results in increased methylation of GATA3 gene25560391
C025643vinclozolinvinclozolin results in increased expression of GATA3 mRNA23034163
C029297vinylidene chloridevinylidene chloride results in decreased expression of GATA3 mRNA26682919
C111237vorinostat"[NOG protein co-treated with vorinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of GATA3 mRNA"27188386
C111237vorinostat[vorinostat co-treated with Isotretinoin] results in increased expression of GATA3 mRNA18769122
C111237vorinostatvorinostat results in increased expression of GATA3 mRNA26272509

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0000976transcription regulatory region sequence-specific DNA binding-IDA19723756  
GO:0000978RNA polymerase II proximal promoter sequence-specific DNA binding-IBA21873635  
GO:0000978RNA polymerase II proximal promoter sequence-specific DNA binding-IDA19674970  
GO:0000981RNA polymerase II transcription factor activity, sequence-specific DNA binding-ISA-  
GO:0000981RNA polymerase II transcription factor activity, sequence-specific DNA binding-ISM19274049  
GO:0000981RNA polymerase II transcription factor activity, sequence-specific DNA binding-NAS19274049  
GO:0000987proximal promoter sequence-specific DNA binding-IDA19232384  
GO:0001076transcription factor activity, RNA polymerase II transcription factor binding-IBA21873635  
GO:0001077transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding-IBA21873635  
GO:0001077transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding-IEA-  
GO:0001078transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding-IMP19674970  
GO:0001158enhancer sequence-specific DNA binding-IEA-  
GO:0003677DNA binding-TAS1871134  
GO:0003700DNA-binding transcription factor activity-IBA21873635  
GO:0003700DNA-binding transcription factor activity-IDA19232384  19805038  20189993  
GO:0003700DNA-binding transcription factor activity-IMP19674970  20368097  
GO:0003713transcription coactivator activity-IDA20484083  
GO:0005134interleukin-2 receptor binding-IEA-  
GO:0005515protein binding-IPI15662016  17075044  19674970  19723756  20484083  25416956  
25910212  26028330  26871637  
GO:0008134transcription factor binding-IPI15016828  
GO:0008270zinc ion binding-IEA-  
GO:0044212transcription regulatory region DNA binding-IDA19735555  19805038  20189993  20484083  
GO:0046983protein dimerization activity-IEA-  
GO:0070888E-box binding-IDA20855495  
GO:0071837HMG box domain binding-IPI18445004  
GO ID GO Term Qualifier Evidence PubMed
GO:0000122negative regulation of transcription by RNA polymerase II-IEA-  
GO:0001701in utero embryonic development-IEA-  
GO:0001709cell fate determination-ISS-  
GO:0001764neuron migration-IEA-  
GO:0001806type IV hypersensitivity-IEA-  
GO:0001822kidney development-IMP19248180  19723756  
GO:0001823mesonephros development-ISS-  
GO:0002088lens development in camera-type eye-IEA-  
GO:0002572pro-T cell differentiation-IEA-  
GO:0003180aortic valve morphogenesis-ISS-  
GO:0003215cardiac right ventricle morphogenesis-ISS-  
GO:0003281ventricular septum development-ISS-  
GO:0006338chromatin remodeling-IEA-  
GO:0006366transcription by RNA polymerase II-TAS1871134  
GO:0006952defense response-TAS7592673  
GO:0006959humoral immune response-IEA-  
GO:0007165signal transduction-ISS-  
GO:0007411axon guidance-IEA-  
GO:0007507heart development-IBA21873635  
GO:0007596blood coagulation-TAS-  
GO:0008285negative regulation of cell proliferation-ISS-  
GO:0008584male gonad development-ISS-  
GO:0009615response to virus-IEP20583921  
GO:0009653anatomical structure morphogenesis-TAS10935639  
GO:0009791post-embryonic development-IEA-  
GO:0009887animal organ morphogenesis-IBA21873635  
GO:0009888tissue development-IBA21873635  
GO:0009967positive regulation of signal transduction-IMP19674970  
GO:0010332response to gamma radiation-IEA-  
GO:0010595positive regulation of endothelial cell migration-IMP19674970  
GO:0010975regulation of neuron projection development-IEA-  
GO:0014065phosphatidylinositol 3-kinase signaling-ISS-  
GO:0016579protein deubiquitination-TAS-  
GO:0019221cytokine-mediated signaling pathway-TAS-  
GO:0030218erythrocyte differentiation-IEA-  
GO:0031929TOR signaling-ISS-  
GO:0032689negative regulation of interferon-gamma production-IEA-  
GO:0032703negative regulation of interleukin-2 production-IEA-  
GO:0032753positive regulation of interleukin-4 production-ISS-  
GO:0033600negative regulation of mammary gland epithelial cell proliferation-IDA19483726  
GO:0035162embryonic hemopoiesis-IEA-  
GO:0035457cellular response to interferon-alpha-IEP20554961  
GO:0035799ureter maturation-IEA-  
GO:0035898parathyroid hormone secretion-IEA-  
GO:0042035regulation of cytokine biosynthetic process-ISS-  
GO:0042421norepinephrine biosynthetic process-ISS-  
GO:0042472inner ear morphogenesis-IEA-  
GO:0043370regulation of CD4-positive, alpha-beta T cell differentiation-IEA-  
GO:0043523regulation of neuron apoptotic process-IEA-  
GO:0043583ear development-IMP19248180  19723756  
GO:0043627response to estrogen-IEP10037815  
GO:0045061thymic T cell selection-IEA-  
GO:0045064T-helper 2 cell differentiation-IEA-  
GO:0045087innate immune response-IEA-  
GO:0045165cell fate commitment-IBA21873635  
GO:0045471response to ethanol-IEA-  
GO:0045582positive regulation of T cell differentiation-ISS-  
GO:0045599negative regulation of fat cell differentiation-IMP20705609  
GO:0045786negative regulation of cell cycle-IMP20189993  
GO:0045892negative regulation of transcription, DNA-templated-IMP19674970  
GO:0045893positive regulation of transcription, DNA-templated-IDA19723756  19805038  
GO:0045893positive regulation of transcription, DNA-templated-IMP19674970  20368097  
GO:0045893positive regulation of transcription, DNA-templated-ISS-  
GO:0045944positive regulation of transcription by RNA polymerase II-IDA19232384  20189993  20484083  
GO:0045944positive regulation of transcription by RNA polymerase II-IMP20855495  
GO:0045944positive regulation of transcription by RNA polymerase II-ISS-  
GO:0048468cell development-IBA21873635  
GO:0048469cell maturation-IEA-  
GO:0048485sympathetic nervous system development-ISS-  
GO:0048538thymus development-IEA-  
GO:0048565digestive tract development-IBA21873635  
GO:0048589developmental growth-IEA-  
GO:0048646anatomical structure formation involved in morphogenesis-IBA21873635  
GO:0048646anatomical structure formation involved in morphogenesis-ISS-  
GO:0050728negative regulation of inflammatory response-IMP19674970  
GO:0050852T cell receptor signaling pathway-ISS-  
GO:0051569regulation of histone H3-K4 methylation-IEA-  
GO:0051897positive regulation of protein kinase B signaling-IMP19674970  
GO:0060017parathyroid gland development-IEA-  
GO:0060037pharyngeal system development-ISS-  
GO:0060065uterus development-ISS-  
GO:0060231mesenchymal to epithelial transition-IDA20189993  
GO:0060374mast cell differentiation-IEA-  
GO:0060676ureteric bud formation-ISS-  
GO:0061085regulation of histone H3-K27 methylation-IEA-  
GO:0061290canonical Wnt signaling pathway involved in metanephric kidney development-ISS-  
GO:0071353cellular response to interleukin-4-IEP20554961  
GO:0071356cellular response to tumor necrosis factor-IEP19674970  
GO:0071442positive regulation of histone H3-K14 acetylation-IEA-  
GO:0071599otic vesicle development-IEA-  
GO:0071773cellular response to BMP stimulus-IEA-  
GO:0072107positive regulation of ureteric bud formation-ISS-  
GO:0072178nephric duct morphogenesis-ISS-  
GO:0072179nephric duct formation-ISS-  
GO:0072182regulation of nephron tubule epithelial cell differentiation-ISS-  
GO:0072602interleukin-4 secretion-IEA-  
GO:0072643interferon-gamma secretion-IEA-  
GO:0072676lymphocyte migration-IDA19805038  
GO:0090102cochlea development-IEA-  
GO:1901536negative regulation of DNA demethylation-IEA-  
GO:1902036regulation of hematopoietic stem cell differentiation-TAS-  
GO:2000114regulation of establishment of cell polarity-IEA-  
GO:2000146negative regulation of cell motility-IMP20189993  
GO:2000352negative regulation of endothelial cell apoptotic process-IMP19674970  
GO:2000553positive regulation of T-helper 2 cell cytokine production-IEA-  
GO:2000607negative regulation of cell proliferation involved in mesonephros development-ISS-  
GO:2000611positive regulation of thyroid hormone generation-IMP19248180  19723756  
GO:2000617positive regulation of histone H3-K9 acetylation-IEA-  
GO:2000664positive regulation of interleukin-5 secretion-IDA20554961  
GO:2000667positive regulation of interleukin-13 secretion-IDA20554961  
GO:2000667positive regulation of interleukin-13 secretion-IMP20368097  
GO:2000679positive regulation of transcription regulatory region DNA binding-IMP20368097  
GO:2000683regulation of cellular response to X-ray-IMP19735555  
GO:2000703negative regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation-ISS-  
GO:2000734negative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation-ISS-  
GO ID GO Term Qualifier Evidence PubMed
GO:0000790nuclear chromatin-IDA20855495  
GO:0005634nucleus-IBA21873635  
GO:0005634nucleus-IDA19674970  19723756  20189993  22529382  
GO:0005654nucleoplasm-IDA-  
GO:0005654nucleoplasm-TAS-  
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence
R-HSA-109582HemostasisTAS
R-HSA-1280215Cytokine Signaling in Immune systemTAS
R-HSA-162582Signal TransductionTAS
R-HSA-168256Immune SystemTAS
R-HSA-212436Generic Transcription PathwayTAS
R-HSA-392499Metabolism of proteinsTAS
R-HSA-449147Signaling by InterleukinsTAS
R-HSA-5688426DeubiquitinationTAS
R-HSA-5689880Ub-specific processing proteasesTAS
R-HSA-597592Post-translational protein modificationTAS
R-HSA-6785807Interleukin-4 and 13 signalingTAS
R-HSA-73857RNA Polymerase II TranscriptionTAS
R-HSA-74160Gene expression (Transcription)TAS
R-HSA-8878171Transcriptional regulation by RUNX1TAS
R-HSA-8939211ESR-mediated signalingTAS
R-HSA-8939236RUNX1 regulates transcription of genes involved in differentiation of HSCsTAS
R-HSA-9006931Signaling by Nuclear ReceptorsTAS
R-HSA-9018519Estrogen-dependent gene expressionTAS
R-HSA-983231Factors involved in megakaryocyte development and platelet productionTAS

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
28950145Determination of poor prognostic immune features of tumour microenvironment in non-smoking patients with lung adenocarcinoma. (2017 Nov)Kinoshita TEur J Cancer
27568346Programmed Cell Death Ligand 1 Expression in Resected Lung Adenocarcinomas: Association with Immune Microenvironment. (2016 Nov)Huynh TGJ Thorac Oncol
26986948An Interleukin 13 Polymorphism Is Associated with Symptom Severity in Adult Subjects with Ever Asthma. (2016)Accordini SPLoS One
22797725Association analyses identify multiple new lung cancer susceptibility loci and their interactions with smoking in the Chinese population. (2012 Jul 15)Dong JNat Genet
25001933[Imbalance in the expression of Foxp3, T-bet and GATA-3 is correlated with inflammation of chronic obstructive pulmonary disease]. (2014 Jul)Wang CXi Bao Yu Fen Zi Mian Yi Xue Za Zhi
25720858An acute bout of exercise modulate the inflammatory response in peripheral blood mononuclear cells in healthy young men. (2015 May)Ulven SMArch Physiol Biochem
28658564A clustering approach to identify and characterize the asthma and chronic obstructive pulmonary disease overlap phenotype. (2017 Nov)Hirai KClin Exp Allergy
27134767Genome-wide time-to-event analysis on smoking progression stages in a family-based study. (2016 May)He LBrain Behav
21930963Prenatal secondhand cigarette smoke promotes Th2 polarization and impairs goblet cell differentiation and airway mucus formation. (2011 Nov 1)Singh SPJ Immunol
27323854Tobacco smoking and methylation of genes related to lung cancer development. (2016 Sep 13)Gao XOncotarget