Gene: CABYR

26256
CABYRa|CABYRc|CABYRc/d|CABYRe|CBP86|CT88|FSP-2|FSP2
calcium binding tyrosine phosphorylation regulated
protein-coding
18q11.2
Ensembl:ENSG00000154040 MIM:612135 Vega:OTTHUMG00000037365 UniprotKB:O75952
NC_000018.10
PubMed
0   ANCO-SNPs
ND
1   
2.034e-1 (AD)  7.759e-1 (ND)   (Frontal_Cortex)
2.137e-1 (AD)  6.659e-1 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
ZNF3650.895
AMPH0.893
WDR70.892
NELL20.892
ATL10.891
CEP410.889
DYNC1I10.889
HSPA12A0.889
AK50.889
PPM1H0.887

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
RNF135-0.508
YES1-0.48
HEY2-0.478
RAB13-0.473
LRAT-0.47
GNG11-0.46
ASB4-0.453
EVC2-0.452
MAPKAPK3-0.451
COPZ2-0.45

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C0095054,4'-diaminodiphenylmethane"4,4'-diaminodiphenylmethane results in decreased expression of CABYR mRNA"18648102
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CABYR mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CABYR mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CABYR mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CABYR mRNA"27188386
D016604Aflatoxin B1Aflatoxin B1 affects the expression of CABYR protein20106945
D016604Aflatoxin B1Aflatoxin B1 results in decreased methylation of CABYR gene27153756
D016604Aflatoxin B1Aflatoxin B1 results in increased expression of CABYR mRNA21632981|2164198
D000393Air PollutantsAir Pollutants analog results in decreased expression of CABYR mRNA21757418
C547126AZM551248AZM551248 results in increased expression of CABYR mRNA22323515
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of CABYR mRNA20064835|2010694
C044887beta-methylcholinebeta-methylcholine affects the expression of CABYR mRNA21179406
C006780bisphenol Abisphenol A results in decreased expression of CABYR mRNA25181051
C006780bisphenol Abisphenol A results in increased methylation of CABYR gene28505145
D020245p-Chloromercuribenzoic Acid"[NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CABYR mRNA"27188386
D020245p-Chloromercuribenzoic Acidp-Chloromercuribenzoic Acid results in increased expression of CABYR mRNA26272509
D002922CiguatoxinsCiguatoxins affects the expression of CABYR mRNA18353800
D016572CyclosporineCyclosporine results in decreased expression of CABYR mRNA27989131
D002945Cisplatin[Cisplatin co-treated with jinfukang] results in increased expression of CABYR mRNA27392435
D002945CisplatinCisplatin results in increased expression of CABYR mRNA27392435
D000431EthanolEthanol affects the expression of CABYR mRNA19167417
D004997Ethinyl Estradiol[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of CABYR mRNA17942748
D005472FluorouracilCABYR protein affects the susceptibility to Fluorouracil16217747
D004397FonofosFonofos results in increased methylation of CABYR promoter22847954
C039281furanfuran results in increased expression of CABYR mRNA24183702
D006861Hydrogen PeroxideHydrogen Peroxide affects the expression of CABYR mRNA20044591
C544151jinfukang[Cisplatin co-treated with jinfukang] results in increased expression of CABYR mRNA27392435
D007854LeadLead affects the splicing of CABYR mRNA28903495
D008694MethamphetamineMethamphetamine results in increased expression of CABYR mRNA26307267
D008727MethotrexateMethotrexate affects the expression of CABYR mRNA18502557
C004925methylmercuric chloridemethylmercuric chloride results in increased expression of CABYR mRNA28001369
D009151Mustard GasMustard Gas results in increased expression of CABYR mRNA25102026
D037742Nanotubes, Carbon"Nanotubes, Carbon results in decreased expression of CABYR mRNA"25620056
D009532NickelNickel results in decreased expression of CABYR mRNA24768652|2558310
D010278ParathionParathion results in increased methylation of CABYR promoter22847954
D010634PhenobarbitalPhenobarbital affects the expression of CABYR mRNA23091169
D010662Phenylmercuric Acetate"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CABYR mRNA"27188386
D010662Phenylmercuric AcetatePhenylmercuric Acetate results in increased expression of CABYR mRNA26272509
C006253pirinixic acidNCF1 protein promotes the reaction [pirinixic acid results in decreased expression of CABYR mRNA]17950772
C006253pirinixic acidpirinixic acid results in decreased expression of CABYR mRNA17950772
D011374ProgesteroneProgesterone results in decreased expression of CABYR mRNA23018184
D011441PropylthiouracilPropylthiouracil results in increased expression of CABYR mRNA24780913
C428725pyridabenpyridaben results in increased expression of CABYR mRNA22563483
D012822Silicon DioxideSilicon Dioxide results in increased expression of CABYR mRNA22300531|2535159
C017947sodium arsenitesodium arsenite results in increased expression of CABYR mRNA25879800
D012999SomanSoman results in decreased expression of CABYR mRNA19281266
D053260SootSoot results in increased expression of CABYR mRNA26551751
D013629TamoxifenTamoxifen results in increased expression of CABYR mRNA25123088
C012568terbufosterbufos results in increased methylation of CABYR promoter22847954
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased expression of CABYR mRNA27913140
D013749TetrachlorodibenzodioxinAHR protein affects the reaction [Tetrachlorodibenzodioxin results in decreased expression of CABYR mRNA]16891777
D013749Tetrachlorodibenzodioxin[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of CABYR mRNA17942748
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased expression of CABYR mRNA16891777|2791314
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased expression of CABYR mRNA27913140
D019772TopotecanCABYR protein affects the susceptibility to Topotecan16217747
D014212TretinoinTretinoin results in decreased expression of CABYR mRNA23724009
D014241TrichloroethyleneTrichloroethylene results in decreased expression of CABYR mRNA25549359
D014635Valproic AcidValproic Acid affects the expression of CABYR mRNA25979313
D014635Valproic AcidValproic Acid results in decreased methylation of CABYR gene29154799

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0005509calcium ion binding-IDA11820818  
GO:0017124SH3 domain binding-NAS11820818  
GO:0046982protein heterodimerization activity-ISS20731842  
GO ID GO Term Qualifier Evidence PubMed
GO:0003351epithelial cilium movement-NAS18421703  
GO:0048240sperm capacitation-NAS11820818  
GO ID GO Term Qualifier Evidence PubMed
GO:0005634nucleus-HDA21630459  
GO:0005634nucleus-IDA-  
GO:0005737cytoplasm-IDA11820818  18421703  
GO:0005829cytosol-IDA-  
GO:0005856cytoskeleton-IEA-  
GO:0031514motile cilium-IDA18421703  
GO:0035686sperm fibrous sheath-IDA11820818  
GO:0097228sperm principal piece-IEA-  
GO:0097229sperm end piece-IEA-  
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
17727719Effect of active smoking on the human bronchial epithelium transcriptome. (2007 Aug 29)Chari RBMC Genomics