Gene: GC

2638
DBP|DBP-maf|DBP/GC|GRD3|Gc-MAF|GcMAF|HEL-S-51|VDB|VDBG|VDBP
GC, vitamin D binding protein
protein-coding
4q13.3
Ensembl:ENSG00000145321 MIM:139200 Vega:OTTHUMG00000129915 UniprotKB:P02774
NG_012837.2
PubMed
CD|OD|ND|AD
229   
NA (AD)  NA (ND)   (Frontal_Cortex)
1.208e-1 (AD)  7.622e-1 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
APOH0.655
FGA0.635
FGG0.626
FGB0.623
AMBP0.612
HP0.6
ALB0.589
ORM10.583
APOC30.566
APCS0.528

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
PRKXP1-0.176
TMOD4-0.176
CHRND-0.175
GOLGA8N-0.172
GAS2L2-0.171
CCDC40-0.17
PPP1R14D-0.169
RGR-0.167
PCDHB11-0.164
SLC13A2-0.159

Drugs/Compounds

ID Drug Name Drug Type CAS Num Status Role
DB00136CalcitriolSmall Molecule32222-06-3Approved|NutraceuticalTarget
DB11094Vitamin DSmall Molecule1406-16-2Approved|NutraceuticalTarget
DB00169CholecalciferolSmall Molecule67-97-0Approved|NutraceuticalCarrier
DB01436AlfacalcidolSmall Molecule41294-56-8Approved|NutraceuticalCarrier
DB04224Oleic AcidSmall Molecule112-80-1Approved|InvestigationalCarrier
ID Drug Name Action PubMed
C5112952,2',4,4'-tetrabromodiphenyl ether"2,2',4,4'-tetrabromodiphenyl ether results in decreased expression of GC mRNA"25614096
C1111182',3,3',4',5-pentachloro-4-hydroxybiphenyl"2',3,3',4',5-pentachloro-4-hydroxybiphenyl results in decreased expression of GC mRNA"19114083
C10445025-hydroxyvitamin DGC gene SNP affects the abundance of 25-hydroxyvitamin D20363324|2458711
C0235142,6-dinitrotoluene"2,6-dinitrotoluene affects the expression of GC mRNA"21346803
C5211672-methylene-19-nor-(20S)-1 alpha-hydroxy-bishomopregnacalciferol2-methylene-19-nor-(20S)-1 alpha-hydroxy-bishomopregnacalciferol binds to GC protein17444814
C0095054,4'-diaminodiphenylmethane"4,4'-diaminodiphenylmethane results in decreased expression of GC mRNA"25380136
C0293704-toluidine4-toluidine results in increased expression of GC mRNA27638505
D000082AcetaminophenAcetaminophen results in decreased expression of GC protein3115882
D000082AcetaminophenAcetaminophen results in decreased expression of GC mRNA26946349
D000082AcetaminophenAcetaminophen results in decreased expression of GC mRNA29067470
D000082AcetaminophenAcetaminophen results in decreased expression of GC protein11510020
D000082AcetaminophenAcetaminophen affects the expression of GC mRNA17562736
D000082AcetaminophenAcetaminophen affects the expression of GC protein16099942
D000082AcetaminophenAcetaminophen results in increased expression of GC mRNA23288050
D000082AcetaminophenAcetaminophen results in increased expression of GC protein16687475
C006418adrenocorticotropin zincadrenocorticotropin zinc results in increased expression of GC mRNA19920212
D016604Aflatoxin B1Aflatoxin B1 affects the expression of GC protein20106945
D016604Aflatoxin B1Aflatoxin B1 results in decreased methylation of GC gene27153756
D016604Aflatoxin B1[Aflatoxin B1 co-treated with Buthionine Sulfoximine] results in increased expression of GC mRNA23288050
D016604Aflatoxin B1Aflatoxin B1 results in increased expression of GC mRNA23288050
D000638AmiodaroneAmiodarone results in decreased expression of GC mRNA26946349
D000643Ammonium ChlorideAmmonium Chloride affects the expression of GC mRNA16483693
C015001arsenitearsenite results in increased expression of GC mRNA18929588
C015001arseniteTRP53 protein affects the reaction [arsenite results in increased expression of GC mRNA]18929588
C006703benzo(b)fluoranthenebenzo(b)fluoranthene results in increased expression of GC mRNA26377693
C041512benzo(b)fluorene[Benzophenanthridines analog co-treated with benzo(b)fluorene co-treated with retene] results in decreased expression of GC mRNA22120849
D053119Benzophenanthridines[Benzophenanthridines analog co-treated with benzo(b)fluorene co-treated with retene] results in decreased expression of GC mRNA22120849
D053119BenzophenanthridinesBenzophenanthridines analog results in decreased expression of GC mRNA22120849
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of GC mRNA26001963
C095105bexarotenebexarotene results in decreased expression of GC mRNA16648578
C006780bisphenol Abisphenol A results in decreased expression of GC mRNA25181051
D001761BleomycinBleomycin results in increased expression of GC protein25933445
C032036bromobenzenebromobenzene results in increased expression of GC mRNA15056800|2328805
D019328Buthionine Sulfoximine[Aflatoxin B1 co-treated with Buthionine Sulfoximine] results in increased expression of GC mRNA23288050
D002104CadmiumGC protein binds to Cadmium23896426
D002104CadmiumCadmium results in increased expression of GC mRNA24067728
C055494caffeic acid phenethyl ester[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of GC mRNA20360939
D002118CalciumCalcium affects the expression of GC mRNA15913539
D002244CarbonGC gene SNP affects the susceptibility to Carbon21138591
D002251Carbon TetrachlorideCarbon Tetrachloride affects the expression of GC mRNA17484886
D002251Carbon TetrachlorideCarbon Tetrachloride results in decreased expression of GC mRNA24381012
C041167chromium nitratechromium nitrate results in decreased expression of GC protein23618972
D002994ClofibrateClofibrate results in decreased expression of GC mRNA12851107
D002995Clofibric Acid[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of GC mRNA17602206
C018021cobaltous chloridecobaltous chloride results in decreased expression of GC mRNA24386269
D003300CopperGC protein binds to Copper23896426
C030123coumarincoumarin results in decreased expression of GC mRNA26946349
D016572CyclosporineCyclosporine results in decreased expression of GC mRNA20106945|2798913
D016572CyclosporineCyclosporine results in decreased expression of GC mRNA21865292
D016572CyclosporineCyclosporine results in increased expression of GC mRNA21865292
D002945CisplatinCisplatin results in increased secretion of GC protein28885000
D004008Diclofenac"[Diclofenac co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of GC protein"25772430
D004052Diethylnitrosamine[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of GC mRNA20360939
D004052Diethylnitrosamine[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of GC mRNA17602206
D002117CalcitriolGC protein affects the abundance of Calcitriol6894152
D002117CalcitriolGC protein affects the transport of Calcitriol15820770
D002117CalcitriolGC protein polymorphism binds to Calcitriol8370586
D002117CalcitriolCalcitriol binds to GC protein17444814
D004128DimethylnitrosamineDimethylnitrosamine results in decreased expression of GC mRNA25380136
D004317DoxorubicinDoxorubicin results in increased expression of GC mRNA15033991
D004317DoxorubicinDoxorubicin results in increased secretion of GC protein28885000
D004997Ethinyl EstradiolEthinyl Estradiol affects the expression of GC mRNA17555576
D004997Ethinyl EstradiolEthinyl Estradiol results in increased expression of GC mRNA17942748
D004997Ethinyl Estradiol[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of GC mRNA17942748
C039281furanfuran binds to GC protein22240984
C039281furanfuran results in increased methylation of GC gene22079235
D019833GenisteinGenistein results in increased expression of GC protein22649256
C561695(+)-JQ1 compound(+)-JQ1 compound results in decreased expression of GC mRNA26752646
D007854LeadGC protein binds to Lead23896426
C008261lead acetatelead acetate results in increased expression of GC mRNA22641619
C482199lipopolysaccharide, E coli O55-B5"[Diclofenac co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of GC protein"25772430
C482199lipopolysaccharide, E coli O55-B5"lipopolysaccharide, E coli O55-B5 results in increased expression of GC protein"25772430
C030957methylmercury IImethylmercury II results in decreased expression of GC mRNA17905399
D037742Nanotubes, Carbon"Nanotubes, Carbon affects the expression of GC protein"21135415
D037742Nanotubes, Carbon"Nanotubes, Carbon analog results in increased expression of GC mRNA"25554681
D037742Nanotubes, Carbon"Nanotubes, Carbon results in increased expression of GC mRNA"25554681
D037742Nanotubes, Carbon"Nanotubes, Carbon results in increased secretion of GC protein"25598225
D0150581-Naphthylisothiocyanate1-Naphthylisothiocyanate results in decreased expression of GC mRNA25380136
C051752nefazodonenefazodone results in decreased expression of GC mRNA24136188
D009532NickelGC protein binds to Nickel23896426
C012655nimesulidenimesulide results in decreased expression of GC mRNA24136188
C002741N-nitrosomorpholineN-nitrosomorpholine results in increased expression of GC mRNA23288050
C025589ochratoxin Aochratoxin A results in decreased expression of GC mRNA18417182
C076029olanzapineolanzapine affects the phosphorylation of GC protein25821032
D010278ParathionGC gene SNP affects the susceptibility to Parathion23833127
C522391perfluorododecanoic acidperfluorododecanoic acid results in decreased expression of GC protein26168851
C101814perfluoro-n-undecanoic acidperfluoro-n-undecanoic acid results in decreased expression of GC mRNA23602845
C006253pirinixic acid[pirinixic acid co-treated with PPARA] results in decreased expression of GC mRNA20813756
C006253pirinixic acidpirinixic acid results in decreased expression of GC mRNA20813756
D028321Plant PreparationsPlant Preparations results in increased expression of GC protein28284660
C027373potassium chromate(VI)potassium chromate(VI) results in decreased expression of GC protein23618972
D011192Potassium DichromatePotassium Dichromate results in decreased expression of GC mRNA23608068
C009007potassium persulfatepotassium persulfate results in increased expression of GC protein20815409
C447880retene[Benzophenanthridines analog co-treated with benzo(b)fluorene co-treated with retene] results in decreased expression of GC mRNA22120849
D012439SaccharinSaccharin results in decreased expression of GC mRNA26946349
D012524SarinSarin results in increased expression of GC protein26778279
D012822Silicon DioxideSilicon Dioxide results in increased expression of GC mRNA22431001
C017947sodium arsenitesodium arsenite affects the expression of GC mRNA17450228
D053260SootSoot results in increased expression of GC mRNA26551751
D010042OuabainOuabain affects the expression of GC protein17268060
D016559TacrolimusTacrolimus results in decreased expression of GC mRNA21865292
C012568terbufosGC gene SNP affects the susceptibility to terbufos23833127
D013749Tetrachlorodibenzodioxin[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of GC mRNA17942748
D013792ThalidomideThalidomide results in decreased expression of GC mRNA28892372
D013853ThioacetamideThioacetamide results in increased expression of GC mRNA23288050
C009495titanium dioxidetitanium dioxide results in decreased expression of GC mRNA23557971
D014212TretinoinTretinoin results in increased expression of GC mRNA23830798
D014502Uranyl NitrateUranyl Nitrate results in increased expression of GC protein23261757
D001335Vehicle EmissionsVehicle Emissions results in decreased methylation of GC gene25487561
D001335Vehicle EmissionsVehicle Emissions results in decreased methylation of GC gene25560391
D014807Vitamin DGC protein polymorphism binds to Vitamin D metabolite8370586
D014807Vitamin DVitamin D binds to GC protein25590278
D014807Vitamin DLRP2 protein binds to and results in increased uptake of [Vitamin D binds to GC protein]10052453
D014807Vitamin DVitamin D binds to GC protein10052453
D014807Vitamin DGC protein binds to Vitamin D24381012
C088658zoledronic acidzoledronic acid results in increased expression of GC protein28871336

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0003779actin binding-IPI12119014  
GO:0005499vitamin D binding-TAS1696927  
GO:0090482vitamin transmembrane transporter activity-IEA-  
GO:1902118calcidiol binding-IDA11799400  
GO ID GO Term Qualifier Evidence PubMed
GO:0035461vitamin transmembrane transport-IEA-  
GO:0042359vitamin D metabolic process-TAS-  
GO:0051180vitamin transport-TAS1696927  
GO ID GO Term Qualifier Evidence PubMed
GO:0005576extracellular region-NAS14718574  
GO:0005576extracellular region-TAS-  
GO:0005615extracellular space-HDA16502470  
GO:0005829cytosol-TAS-  
GO:0043202lysosomal lumen-TAS-  
GO:0070062extracellular exosome-HDA23533145  
GO:0072562blood microparticle-HDA22516433  
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence
R-HSA-1430728MetabolismTAS
R-HSA-196791Vitamin D (calciferol) metabolismTAS
R-HSA-556833Metabolism of lipidsTAS
R-HSA-8957322Metabolism of steroidsTAS

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
22864938Dietary, lifestyle and clinicopathological factors associated with APC mutations and promoter methylation in colorectal cancers from the EPIC-Norfolk study. (2012 Nov)Gay LJJ Pathol
10578664[Monoamine oxidase, tribulin, isatin: basic and applied medical aspects]. (1999)Medvedev AEVestn Ross Akad Med Nauk
26485766Genetic variant of PRKAA1 and gastric cancer risk in an eastern Chinese population. (2015 Dec 15)Qiu LXOncotarget
19960570Glutathione-S-transferase (GSTM1, GSTT1) and the risk of gastrointestinal cancer in a Korean population. (2009 Dec 7)Piao JMWorld J Gastroenterol
21215087[Study on the association between DNA double-strand break repair gene NBS1 polymorphisms and susceptibility on lung cancer]. (2010 Feb)Fan LHZhonghua Liu Xing Bing Xue Za Zhi
28423629Polymorphisms in human telomerase reverse transcriptase (hTERT) gene, gene- gene and gene-smoking interaction with susceptibility to gastric cancer in Chinese Han population. (2017 Mar 21)Zhang JOncotarget
25874489Association between ADH1B and ADH1C polymorphisms and the risk of head and neck squamous cell carcinoma. (2015 Jun)Ji YBTumour Biol
23399681Pioglitazone potentiates development of morphine-dependence in mice: possible role of NO/cGMP pathway. (2013 May 13)Javadi SBrain Res
24857306[The correlation of vitamin D level and vitamin D-binding protein gene polymorphism in chronic obstructive pulmonary disease]. (2014 Apr)Li XZhonghua Nei Ke Za Zhi
24396479Study of the polymorphisms of cyclooxygenase-2 (-765G>C) and 5-lipoxygenase (1708G>A) in patients with colorectal cancer. (2014 Feb)Pimenta CAOncol Lett
1439542Location and type of gastric carcinoma in relation to pepsinogen I level in blood. (1992 Oct)Chang FYScand J Gastroenterol
28153673Quantitative analysis of menthol in human urine using solid phase microextraction and stable isotope dilution gas chromatography-mass spectrometry. (2017 Feb 15)Huang WJ Chromatogr B Analyt Technol Biomed Life Sci
12024803Effects of whole deletion of CYP2A6 on nicotine metabolism in humans. (2002 May)Zhang XDrug Chem Toxicol
21321788N-nitrosamines are associated with shorter telomere length. (2011 Jul)Li HScand J Work Environ Health
26680482The steroid spectrum during and after quitting smoking. (2015)Jandikova HPhysiol Res
8692183DNA adducts in human carcinogenesis: etiological relevance and structure-activity relationship. (1996 Jun)Bartsch HMutat Res
1394847Enhanced hprt mutant frequency but no significant difference in mutation spectrum between a smoking and a non-smoking human population. (1992 Sep)Vrieling HCarcinogenesis
22475777Association between PPAR-gamma and RXR-alpha gene polymorphism and metabolic syndrome risk: a case-control study of a Chinese Han population. (2012 Apr)Shi HArch Med Res
29796641Tryptophan Metabolism through the Kynurenine Pathway is Associated with Endoscopic Inflammation in Ulcerative Colitis. (2018 May 22)Sofia MAInflamm Bowel Dis
28811774Effects of supervised structured aerobic exercise training program on fasting blood glucose level, plasma insulin level, glycemic control, and insulin resistance in type 2 diabetes mellitus. (2017 May-Jun)Shakil-Ur-Rehman SPak J Med Sci
21750916Macrophage migration inhibitory factor gene -173G>C polymorphism and risk of bladder cancer in southeast China: a case-control analysis. (2012 Mar)Yuan QMol Biol Rep
23850851Plasma 27-hydroxycholesterol/cholesterol ratio is increased in low high density lipoprotein-cholesterol healthy subjects. (2013 Oct)Nunes VSClin Biochem
24198121Cigarette smoking exposure alters pebp1 DNA methylation and protein profile involved in MAPK signaling pathway in mice testis. (2013 Dec)Xu WBiol Reprod
7586163Mutation spectrum of cigarette smoke condensate in Salmonella: comparison to mutations in smoking-associated tumors. (1995 Oct)DeMarini DMCarcinogenesis
15767339PTGS2 (COX-2) -765G > C promoter variant reduces risk of colorectal adenoma among nonusers of nonsteroidal anti-inflammatory drugs. (2005 Mar)Ulrich CMCancer Epidemiol Biomarkers Prev
24365123Association of polymorphisms on chromosome 9p21.3 region with increased susceptibility of abdominal aortic aneurysm in a Chinese Han population. (2014 Apr)Wei YJ Vasc Surg
29086360Evaluation of genotoxic effects in Brazilian agricultural workers exposed to pesticides and cigarette smoke using machine-learning algorithms. (2018 Jan)Tomiazzi JSEnviron Sci Pollut Res Int
8818386p53 mutations in head and neck squamous cell carcinomas from Sudanese snuff (toombak) users. (1996)Lazarus PCancer Detect Prev
26445944Clinicopathologic features of gastric cancer with synchronous and metachronous colorectal cancer in Korea: are microsatellite instability and p53 overexpression useful markers for predicting colorectal cancer in gastric cancer patients? (2016 Jul)Kim HJGastric Cancer
23317230Polymorphisms of XRCC1 and ADPRT genes and risk of noncardia gastric cancer in a Chinese population: a case-control study. (2012)Pan XFAsian Pac J Cancer Prev
17094900[Correlation of p73 polymorphisms to genetic susceptibilities to esophageal carcinoma and gastric cardiac carcinoma]. (2006 Nov)Ge HAi Zheng
28300138Reduced DNA methylation and psychopathology following endogenous hypercortisolism - a genome-wide study. (2017 Mar 16)Glad CASci Rep
8711952Determination of polycyclic aromatic hydrocarbons in smoked fishery products from different smoking kilns. (1996 Jun)Karl HZ Lebensm Unters Forsch
22887904Cyclooxygenase-2-765G>C functional promoter polymorphism and its association with oral squamous cell carcinoma. (2012 Aug)Lakshmi AJ Investig Clin Dent
29777315The MDM2 rs937283 A > G variant significantly increases the risk of lung and gastric cancer in Chinese population. (2018 May 18)Chen BInt J Clin Oncol
23192911The risk of infections associated with rheumatoid arthritis, with its comorbidity and treatment. (2013 Jan)Listing JRheumatology (Oxford)
11562787Molecular analysis of p53 and K-ras in lung carcinomas of coal miners. (2001 Oct)Sarkar FHInt J Mol Med
15495595[Genetic susceptibility and risk of gastric cancer in a human population of Cauca, Colombia]. (2004 Jun)Torres MMBiomedica
18173398Cyclooxygenase-2 Gene-765 single nucleotide polymorphism as a protective factor against periodontitis in Taiwanese. (2008 Jan)Ho YPJ Clin Periodontol
17055359IL6 G-174C associated with sudden infant death syndrome in a Caucasian Australian cohort. (2006 Oct)Moscovis SMHum Immunol
29108239Interactions between vitamin D receptor (VDR) gene and Interleukin-6 gene and environment factors on coronary heart disease risk in a Chinese Han population. (2017 Oct 3)Jun MOncotarget
15069555P53 codon 72 polymorphism and risk of gastric cancer in a Chinese population. (2004 May)Shen HOncol Rep
26622766Cyclooxygenase-2 gene polymorphisms and the risk of colorectal cancer: A population-based study. (2015 Sep)Li HOncol Lett
21655952Functional polymorphism of cyclooxygenase-2 gene (G-765C) in chronic obstructive pulmonary disease patients. (2012 Mar)Pietras TMol Biol Rep
24838369Variation in AKR1C3, which encodes the neuroactive steroid synthetic enzyme 3alpha-HSD type 2 (17beta-HSD type 5), moderates the subjective effects of alcohol. (2014 Sep)Milivojevic VPsychopharmacology (Berl)
22595727Gastric cancer carcinogenesis and tumor progression. (2012 May-Jun)Corso GAnn Ital Chir
23406618High concentrations of plasma n3 fatty acids are associated with decreased risk for late age-related macular degeneration. (2013 Apr)Merle BMJ Nutr
8168608Carbamylation of human lens gamma-crystallins: relevance to cataract formation. (1993 Sep)Liu XYan Ke Xue Bao
24975047Transmembrane protein 106A is silenced by promoter region hypermethylation and suppresses gastric cancer growth by inducing apoptosis. (2014 Aug)Xu DJ Cell Mol Med
22901197Elevated circulating CD19+ lymphocytes predict survival advantage in patients with gastric cancer. (2012)Yu QMAsian Pac J Cancer Prev
9288889Immunochemical, 32P-postlabeling, and GC/MS detection of 4-aminobiphenyl-DNA adducts in human peripheral lung in relation to metabolic activation pathways involving pulmonary N-oxidation, conjugation, and peroxidation. (1997 Aug 1)Culp SJMutat Res
15895459Gastric cancer: new genetic developments. (2005 Jun 1)Lynch HTJ Surg Oncol
26295909In vivo detection of the new psychoactive substance AM-694 and its metabolites. (2015 Nov)Bertol EForensic Sci Int
29748531XRCC2 Polymorphisms and Environmental Factors Predict High Risk of Colorectal Cancer. (2018 May 7)Wang LMed Sci Monit
28101114Dietary and Socio-Demographic Determinants of Serum Persistent Organic Pollutants (POPs) Levels in Pregnant Women in Tehran. (2016 Sep)Eslami BJ Family Reprod Health
27583352The hOGG1 Ser326Cys gene polymorphism and susceptibility for bladder cancer: a meta-analysis. (2016 Sep-Oct)Wenjuan CInt Braz J Urol
28415781Relevance of DNA repair gene polymorphisms to gastric cancer risk and phenotype. (2017 May 30)Carrera-Lasfuentes POncotarget
23979980Quantitative assessment of the influence of glutathione S-transferase T1 null variant on gastric cancer risk. (2014 Jan)Wang QTumour Biol
26895959Association Between MIF-AS rs755622 and Nephrolithiasis Risk in a Chinese Population. (2016 Feb 20)Ma GMed Sci Monit
24824149Use of floss/interdental brushes is associated with lower risk for new cardiovascular events among patients with coronary heart disease. (2015 Apr)Reichert SJ Periodontal Res
24776622Efficacy and safety of combined parenteral and oral steroid therapy in Graves' orbitopathy. (2014 Apr-Jun)Nedeljkovic Beleslin BHormones (Athens)
25434319Phospholipase C epsilon 1 (PLCE1) haplotypes are associated with increased risk of gastric cancer in Kashmir Valley. (2014 Nov-Dec)Malik MASaudi J Gastroenterol
23085321Haplotype study of the CYP4A11 gene and coronary artery disease in Han and Uygur populations in China. (2013 Jan 10)Fu ZGene
25197540Pepsinogen I and II, Gastrin and Cag A Serum Levels in Shiraz. (2011 Sep)Shamsdin SAMiddle East J Dig Dis
17963453Quantitative profiling of folate and one-carbon metabolism in large-scale epidemiological studies by mass spectrometry. (2007)Ueland PMClin Chem Lab Med
26191352Association of endothelial nitric oxide synthase gene T-786C promoter polymorphism with gastric cancer. (2015 Jul 15)Krishnaveni DWorld J Gastrointest Oncol
21383443Compounds enhanced in a mass spectrometric profile of smokers' exhaled breath versus non-smokers as determined in a pilot study using PTR-MS. (2008 Jun)Kushch IJ Breath Res
21502924Intrafamilial aggregation of gastric cancer: a comprehensive approach including environmental factors, Helicobacter pylori virulence, and genetic susceptibility. (2011 May)Shin CMEur J Gastroenterol Hepatol
23007982Meta-analysis confirms that a common G/C variant in the pre-miR-146a gene contributes to cancer susceptibility and that ethnicity, gender and smoking status are risk factors. (2012 Aug 31)Wang AXGenet Mol Res
24568525Lack of associations between Vitamin D metabolism-related gene variants and risk of colorectal cancer. (2014)Mahmoudi TAsian Pac J Cancer Prev
25326754MiR-146a rs2910164 G/C polymorphism and gastric cancer susceptibility: a meta-analysis. (2014 Oct 20)Xu ZBMC Med Genet
26828318Volatile organic compounds discriminate between eosinophilic and neutrophilic inflammation in vitro. (2016 Feb 1)Schleich FNJ Breath Res
21700414Association of death receptor 4, Caspase 3 and 5 gene polymorphism with increased risk to bladder cancer in North Indians. (2011 Aug)Mittal RDEur J Surg Oncol
28657413Dynamic measurement of newly formed carbonyl compounds in vapors from electronic cigarettes. (2017 Apr)Sala CEur J Mass Spectrom (Chichester)
8986227Alteration of glutamyltranspeptidase binding proteins in postmortem brains of heroin addicts. (1996 Dec)Hashimoto EAlcohol Clin Exp Res
21850685The polymorphism and haplotypes of PIN1 gene are associated with the risk of lung cancer in Southern and Eastern Chinese populations. (2011 Nov)Lu JHum Mutat
19493696Assessment of polychlorinated biphenyl congeners, thyroid stimulating hormone, and free thyroxine among New York state anglers. (2009 Nov)Bloom MSInt J Hyg Environ Health
27457487Genetic variations of DICKKOPF family genes might not be associated with gastric cancer susceptibility. (2016 Jul 26)Wu JBMC Gastroenterol
26911630Lipoprotein(a) level and MIF gene variant predict incident metabolic syndrome and mortality. (2016 Feb)Onat AJ Investig Med
19021927A gas chromatography-isotope dilution high-resolution mass spectrometry method for quantification of isomeric benzo[a]pyrene diol epoxide hemoglobin adducts in humans. (2008 Nov-Dec)Ragin ADJ Anal Toxicol
16207551Additive effects of the chemokine receptor 2, vitamin D receptor, interleukin-6 polymorphisms and cardiovascular risk factors on the prevalence of myocardial infarction in patients below 65 years. (2005 Oct 20)Ortlepp JRInt J Cardiol
27328977A mucoactive drug carbocisteine ameliorates steroid resistance in rat COPD model. (2016 Aug)Song YPulm Pharmacol Ther
21517234Role of the metalloproteinase-7 (181A>G) polymorphism in gastric cancer susceptibility: a case control study in Kashmir valley. (2011)Malik MAAsian Pac J Cancer Prev
28215083Development of a Zeolite Filter for Removing Polycyclic Aromatic Hydrocarbons (PAHs) from Smoke and Smoked Ingredients while Retaining the Smoky Flavor. (2018 Mar 14)Parker JKJ Agric Food Chem
25253367Role of interstitial collagenase gene promoter polymorphism in the etiology of gastric cancer. (2014 Sep-Oct)Devulapalli KSaudi J Gastroenterol
21044285Analyses of association between PPAR gamma and EPHX1 polymorphisms and susceptibility to COPD in a Hungarian cohort, a case-control study. (2010 Nov 2)Penyige ABMC Med Genet
25479069Serum OPN expression for identification of gastric cancer and atrophic gastritis and its influencing factors. (2014)Chen TPLoS One
20137269[Association of ENA-78, IP-10 and VEGF gene polymorphism with idiopathic pulmonary fibrosis]. (2009 Oct 20)Liu LZhonghua Yi Xue Za Zhi
10863157Mutational spectra at the hypoxanthine-guanine phosphoribosyltransferase (HPRT) locus in T-lymphocytes of nonsmoking and smoking lung cancer patients. (2000 Jun 22)Hackman PMutat Res
26275945Relative importance of summer sun exposure, vitamin D intake, and genes to vitamin D status in Dutch older adults: The B-PROOF study. (2016 Nov)Brouwer-Brolsma EMJ Steroid Biochem Mol Biol
28415779Relationship of p73 gene polymorphism and additional gene-smoking and gene-obesity interaction with non-small cell lung cancer risk. (2017 May 23)Wu QOncotarget
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