Gene: GFAP

2670
ALXDRD
glial fibrillary acidic protein
protein-coding
17q21.31
Ensembl:ENSG00000131095 MIM:137780 Vega:OTTHUMG00000179866 UniprotKB:P14136
NG_008401.1
PubMed
OD|ND|AD
22   
NA (AD)  NA (ND)   (Frontal_Cortex)
5.208e-1 (AD)  5.241e-1 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
SERPINB60.845
NPC20.832
RHOC0.825
ROM10.824
TSPO0.823
RARRES30.82
IFITM30.818
DBI0.812
DTNA0.802
BGN0.802

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
OR4F29-0.516
OR4F5-0.493
ADRA1D-0.492
PPEF1-0.471
ABCC12-0.462
F7-0.46
OR1F1-0.448
NEK10-0.446
MARCH4-0.445
TPBGL-0.444

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C0703791,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester"[1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester co-treated with Egtazic Acid] inhibits the reaction [diphenylditelluride results in increased phosphorylation of GFAP protein]"21879721
C09724015-deoxy-delta(12,14)-prostaglandin J2"15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of GFAP"15254749
C09724015-deoxy-delta(12,14)-prostaglandin J2"15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [ochratoxin A results in decreased expression of GFAP mRNA]"15994020
C09724015-deoxy-delta(12,14)-prostaglandin J2"15-deoxy-delta(12,14)-prostaglandin J2 results in decreased expression of GFAP mRNA"15994020
C0602291-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione"1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [diphenylditelluride results in increased phosphorylation of GFAP protein]"21879721
C0939732-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [diphenylditelluride results in increased phosphorylation of GFAP protein]21879721
C0005162-(2-cresyl)-4H-1-3-2-benzodioxaphosphorin-2-oxide8-Hydroxy-2-(di-n-propylamino)tetralin inhibits the reaction [[Sarin co-treated with 2-(2-cresyl)-4H-1-3-2-benzodioxaphosphorin-2-oxide] results in increased expression of GFAP protein]23692952
C0005162-(2-cresyl)-4H-1-3-2-benzodioxaphosphorin-2-oxide[Sarin co-treated with 2-(2-cresyl)-4H-1-3-2-benzodioxaphosphorin-2-oxide] results in increased expression of GFAP protein23692952
C0942102,2'-(hydroxynitrosohydrazono)bis-ethanamine"2,2'-(hydroxynitrosohydrazono)bis-ethanamine results in decreased expression of GFAP mRNA"16580782
C0142112,3,7,8-tetrachlorodibenzofuran"2,3,7,8-tetrachlorodibenzofuran affects the expression of GFAP mRNA"18343893
C0792702,4,6-tris(dimethylaminomethyl)phenol"2,4,6-tris(dimethylaminomethyl)phenol results in increased expression of GFAP mRNA"22954530
C0112692,5-hexanedione"2,5-hexanedione results in decreased expression of GFAP protein"19033394
C0112692,5-hexanedione"2,5-hexanedione results in increased expression of GFAP protein"19033394
C0303702-methoxy-5-(2',3',4'-trimethoxyphenyl)tropone"2-methoxy-5-(2',3',4'-trimethoxyphenyl)tropone results in increased expression of GFAP mRNA"20206263
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide results in increased expression of GFAP protein"25670856
C5605976,7-epoxy-5,17-dihydroxy-1-oxowitha-2,24-dienolide"6,7-epoxy-5,17-dihydroxy-1-oxowitha-2,24-dienolide inhibits the reaction [Scopolamine Hydrobromide results in decreased expression of GFAP protein]"22096544
C0801227-nitroindazole[7-nitroindazole co-treated with pimagedine] promotes the reaction [Capsaicin results in increased expression of GFAP protein]20826152
C0801227-nitroindazole[7-nitroindazole co-treated with pimagedine] results in increased expression of GFAP protein20826152
C0801227-nitroindazole7-nitroindazole inhibits the reaction [Capsaicin results in increased expression of GFAP protein]20826152
C106538abacavirabacavir results in increased expression of GFAP protein19358275
D000082Acetaminophen[Clofibrate co-treated with Acetaminophen] affects the expression of GFAP mRNA17585979
D000082AcetaminophenPPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of GFAP mRNA]17585979
D019342Acetic AcidAcetic Acid results in decreased expression of GFAP protein21296659
D000108AcetylcarnitineAcetylcarnitine results in decreased expression of GFAP mRNA19555370
D000111AcetylcysteineAcetylcysteine inhibits the reaction [Streptozocin results in decreased expression of GFAP protein]28499986
D020106AcrylamideAcrylamide results in increased expression of GFAP protein19426797
D000376AgmatineAgmatine inhibits the reaction [MBP protein results in increased expression of GFAP protein]24070732
D000376AgmatineNOS2 gene mutant form promotes the reaction [Agmatine inhibits the reaction [MBP protein results in increased expression of GFAP protein]]24070732
D000393Air PollutantsAir Pollutants affects the expression of GFAP protein24690596
D000395Air Pollutants, Occupational"Air Pollutants, Occupational results in decreased expression of GFAP mRNA"20224926
D000395Air Pollutants, Occupational"Air Pollutants, Occupational results in increased expression of GFAP mRNA"20224926
C069512alpha-methylepininealpha-methylepinine results in decreased expression of GFAP protein10580546
D024502alpha-Tocopherolalpha-Tocopherol results in increased expression of GFAP protein18942769
D000535AluminumAluminum results in increased expression of GFAP protein16545059
D000535AluminumVitamin E inhibits the reaction [Aluminum results in increased expression of GFAP protein]16545059
C010845aluminum chloridealuminum chloride results in decreased expression of GFAP mRNA9826787
C010845aluminum chloridealuminum chloride results in increased expression of GFAP protein26339337
C010845aluminum chlorideCaffeine inhibits the reaction [aluminum chloride results in increased expression of GFAP protein]26339337
C104223aluminum lactatealuminum lactate results in increased expression of GFAP protein14743440
C104223aluminum lactatealuminum lactate affects the localization of GFAP protein12397369
C011164amentoflavone"amentoflavone inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of GFAP protein]"28185818
D005680gamma-Aminobutyric Acidgamma-Aminobutyric Acid results in increased expression of GFAP protein17845906
D000638AmiodaroneAmiodarone results in increased expression of GFAP mRNA22954530|2565976
D000639AmitriptylineAmitriptyline results in increased expression of GFAP mRNA22954530
D000641AmmoniaAmmonia results in decreased expression of GFAP mRNA20217200
D000641AmmoniaIL1B protein promotes the reaction [Ammonia results in decreased expression of GFAP mRNA]20217200
D000643Ammonium ChlorideAmmonium Chloride results in decreased expression of GFAP mRNA16483693
D000643Ammonium ChlorideAmmonium Chloride results in decreased expression of GFAP protein16483693
D003913DextroamphetamineDextroamphetamine results in increased expression of GFAP protein15337264
D000661AmphetamineAmphetamine results in increased expression of GFAP protein15814102
D000661AmphetamineAmphetamine results in increased expression of GFAP mRNA15183010|2022327
D000661AmphetamineAmphetamine results in increased expression of GFAP protein15183010
D001151ArsenicArsenic affects the methylation of GFAP gene25304211
D001205Ascorbic AcidAscorbic Acid results in decreased expression of GFAP protein15372504
C030693AshwagandhaAshwagandha inhibits the reaction [Scopolamine Hydrobromide results in decreased expression of GFAP mRNA]22096544
C030693AshwagandhaAshwagandha inhibits the reaction [Scopolamine Hydrobromide results in decreased expression of GFAP protein]22096544
C030693AshwagandhaAshwagandha inhibits the reaction [lead nitrate results in increased expression of GFAP mRNA]24987671
C030693AshwagandhaAshwagandha inhibits the reaction [lead nitrate results in increased expression of GFAP protein]24987671
D001241AspirinAspirin results in decreased expression of GFAP mRNA16516312
D001241AspirinAspirin results in decreased expression of GFAP protein16516312
D001241AspirinAspirin results in decreased expression of GFAP mRNA21353610
D001241AspirinAspirin results in increased expression of GFAP mRNA22954530
C005948astaxanthineastaxanthine results in decreased expression of GFAP mRNA19555370
D001285AtropineAtropine inhibits the reaction [Methyl Parathion results in decreased expression of GFAP mRNA]20826231
C005177benserazide, levodopa drug combination"benserazide, levodopa drug combination inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of GFAP protein]"28185818
D001564Benzo(a)pyreneBenzo(a)pyrene results in decreased expression of GFAP mRNA22316170
D001564Benzo(a)pyreneBenzo(a)pyrene results in decreased expression of GFAP mRNA20127859
D004958Estradiol[Estradiol co-treated with Progesterone] promotes the reaction [Cuprizone results in increased expression of GFAP mRNA]19031445
C006780bisphenol Abisphenol A results in decreased methylation of GFAP promoter27312807
C006780bisphenol Abisphenol A results in increased expression of GFAP mRNA24824810
C006780bisphenol Abisphenol A results in increased expression of GFAP protein16684133|1686091
C006780bisphenol ATamoxifen inhibits the reaction [bisphenol A results in increased expression of GFAP protein]16860915
C006780bisphenol Abisphenol A affects the expression of GFAP mRNA25181051
C006780bisphenol Abisphenol A results in increased expression of GFAP mRNA25381574|2596372
C006780bisphenol ACurcumin inhibits the reaction [bisphenol A results in increased expression of GFAP mRNA]25963729
D001786Blood Glucose[Oxygen deficiency co-treated with Blood Glucose deficiency] results in increased expression of GFAP protein25727173
D001786Blood Glucoseresveratrol inhibits the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in increased expression of GFAP protein]25727173
C013418bromfenacoumbromfenacoum results in decreased expression of GFAP protein28903499
D0151248-Bromo Cyclic Adenosine Monophosphate8-Bromo Cyclic Adenosine Monophosphate inhibits the reaction [ochratoxin A results in decreased expression of GFAP mRNA]15994020
D0151248-Bromo Cyclic Adenosine Monophosphate8-Bromo Cyclic Adenosine Monophosphate results in increased expression of GFAP mRNA15994020
C099813bromochloroacetic acidbromochloroacetic acid results in decreased expression of GFAP protein21296659
D020122tert-Butylhydroperoxidetert-Butylhydroperoxide results in decreased expression of GFAP protein24394546
D020122tert-Butylhydroperoxidetert-Butylhydroperoxide results in increased expression of GFAP protein24394546
D002087ButyratesButyrates results in increased expression of GFAP mRNA19360904
D002087ButyratesButyrates results in increased expression of GFAP protein19360904
D002087ButyratesFinasteride inhibits the reaction [Butyrates results in increased expression of GFAP mRNA]19360904
D002087ButyratesFinasteride inhibits the reaction [Butyrates results in increased expression of GFAP protein]19360904
D019256Cadmium ChlorideCadmium Chloride results in decreased expression of GFAP protein27080906
D019256Cadmium ChlorideCadmium Chloride results in increased expression of GFAP protein21796402
D019256Cadmium ChlorideCadmium Chloride results in increased expression of GFAP mRNA24982889
D019256Cadmium Chloride[Cadmium Chloride co-treated with sodium arsenite co-treated with lead acetate] results in decreased expression of GFAP protein20829427
D019256Cadmium ChlorideCadmium Chloride results in decreased expression of GFAP protein20829427
D019256Cadmium ChlorideCR8 compound inhibits the reaction [[sodium arsenite co-treated with lead acetate co-treated with Cadmium Chloride] results in decreased expression of GFAP protein]24481447
D019256Cadmium Chloride[sodium arsenite co-treated with Cadmium Chloride co-treated with lead acetate] results in increased expression of GFAP protein26396915
D019256Cadmium Chloride[sodium arsenite co-treated with lead acetate co-treated with Cadmium Chloride] promotes the reaction [PPARG protein binds to GFAP promoter]24481447
D019256Cadmium Chloride[sodium arsenite co-treated with lead acetate co-treated with Cadmium Chloride] results in decreased expression of GFAP mRNA24481447
D019256Cadmium Chloride[sodium arsenite co-treated with lead acetate co-treated with Cadmium Chloride] results in decreased expression of GFAP protein24481447
D019256Cadmium Chloride[[sodium arsenite co-treated with lead acetate co-treated with Cadmium Chloride] results in increased phosphorylation of and results in increased activity of PPARG protein] which results in decreased expression of GFAP protein24481447
C055494caffeic acid phenethyl estercaffeic acid phenethyl ester results in increased expression of GFAP protein20836997
C055494caffeic acid phenethyl esterNGFR protein affects the susceptibility to [caffeic acid phenethyl ester results in increased expression of GFAP protein]20836997
D002110Caffeine"Caffeine promotes the reaction [N-Methyl-3,4-methylenedioxyamphetamine results in increased expression of GFAP protein]"19882200
D002110CaffeineCaffeine inhibits the reaction [aluminum chloride results in increased expression of GFAP protein]26339337
D002118CalciumCalcium affects the reaction [diphenylditelluride results in increased phosphorylation of GFAP protein]21879721
D002118CalciumCalcium deficiency inhibits the reaction [Ethanol results in increased expression of GFAP protein]17888892
C059041calyculin Acalyculin A inhibits the reaction [diphenylditelluride results in decreased phosphorylation of GFAP protein]21863293
D002211CapsaicinCapsaicin results in increased expression of GFAP mRNA18405923
D002211Capsaicin[7-nitroindazole co-treated with pimagedine] promotes the reaction [Capsaicin results in increased expression of GFAP protein]20826152
D002211Capsaicin7-nitroindazole inhibits the reaction [Capsaicin results in increased expression of GFAP protein]20826152
D002211CapsaicinCapsaicin inhibits the reaction [IL6 protein results in increased expression of GFAP mRNA]19285962
D002211CapsaicinCapsaicin results in increased expression of GFAP protein20826152
D002211Capsaicincapsazepine inhibits the reaction [Capsaicin results in increased expression of GFAP protein]20826152
D002211Capsaicinpimagedine inhibits the reaction [Capsaicin results in increased expression of GFAP protein]20826152
C071423capsazepinecapsazepine inhibits the reaction [Capsaicin results in increased expression of GFAP protein]20826152
D002235CarbofuranCarbofuran results in decreased expression of GFAP protein22240977
D002235CarbofuranCarbofuran results in increased expression of GFAP mRNA28982980
D002251Carbon TetrachlorideCarbon Tetrachloride results in increased expression of GFAP protein19747501
D002251Carbon TetrachlorideLuteolin inhibits the reaction [Carbon Tetrachloride results in increased expression of GFAP protein]19747501
C010063carbonyl sulfidecarbonyl sulfide affects the expression of GFAP mRNA19395590
D002330CarmustineCarmustine results in decreased expression of GFAP mRNA15980968
D002330CarmustineCarmustine results in decreased expression of GFAP protein17572393
D002330CarmustineMelatonin inhibits the reaction [Carmustine results in decreased expression of GFAP protein]17572393
D010133p-Chloroamphetaminep-Chloroamphetamine results in increased expression of GFAP protein15337264
D004390ChlorpyrifosChlorpyrifos results in decreased expression of GFAP mRNA27018022
D004390ChlorpyrifosChlorpyrifos results in decreased expression of GFAP mRNA17452286|2069171
D004390ChlorpyrifosChlorpyrifos results in increased expression of GFAP mRNA16675515
D002794Choline[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of GFAP gene20938992
D002994Clofibrate[Clofibrate co-treated with Acetaminophen] affects the expression of GFAP mRNA17585979
D002994ClofibratePPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of GFAP mRNA]17585979
D003022ClotrimazoleClotrimazole results in increased expression of GFAP protein10223459
D003024ClozapineClozapine results in decreased expression of GFAP protein18585900
D003024ClozapineClozapine results in increased expression of GFAP mRNA19441803
C529348CNB 001"CNB 001 inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of GFAP protein]"24995576
C018021cobaltous chloridecobaltous chloride results in increased expression of GFAP mRNA23978538
C018021cobaltous chloridecobaltous chloride results in increased expression of GFAP protein23978538
C018021cobaltous chloridecobaltous chloride results in increased expression of GFAP mRNA23978538
C018021cobaltous chloridecobaltous chloride results in increased expression of GFAP protein23978538
D003042CocaineCocaine results in increased expression of GFAP protein15814102
D003042CocaineCocaine affects the expression of GFAP protein11882367
D003042CocaineCocaine affects the expression of GFAP mRNA20187946
D003042CocaineCocaine affects the expression of GFAP protein12670315
D003042CocaineCocaine results in decreased expression of GFAP protein11391778
C024989coenzyme Q10coenzyme Q10 results in decreased expression of GFAP mRNA19555370
D003300CopperCopper deficiency results in increased expression of GFAP mRNA26033743
C532131CR8 compoundCR8 compound inhibits the reaction [[sodium arsenite co-treated with lead acetate co-treated with Cadmium Chloride] results in decreased expression of GFAP protein]24481447
C532131CR8 compoundCR8 compound inhibits the reaction [troglitazone results in decreased expression of GFAP protein]24481447
D003471CuprizoneCuprizone results in increased expression of GFAP mRNA19031445
D003471Cuprizone[Estradiol co-treated with Progesterone] promotes the reaction [Cuprizone results in increased expression of GFAP mRNA]19031445
D003471CuprizoneCuprizone results in increased expression of GFAP mRNA27523638
D003471CuprizoneCuprizone results in increased expression of GFAP protein27523638
D003474CurcuminCurcumin results in decreased expression of GFAP mRNA19555370
D003474CurcuminCurcumin inhibits the reaction [bisphenol A results in increased expression of GFAP mRNA]25963729
D003474CurcuminCurcumin results in decreased expression of GFAP mRNA25963729
D0187506-Cyano-7-nitroquinoxaline-2,3-dione"6-Cyano-7-nitroquinoxaline-2,3-dione inhibits the reaction [diphenylditelluride results in decreased phosphorylation of GFAP protein]"21863293
C009160cyclonitecyclonite results in increased expression of GFAP mRNA19417177
C009160cyclonitecyclonite results in increased expression of GFAP mRNA25559034
D0150842,4-Dichlorophenoxyacetic Acid"2,4-Dichlorophenoxyacetic Acid results in increased expression of GFAP mRNA"22954530
D003620DantroleneDantrolene inhibits the reaction [diphenylditelluride results in decreased phosphorylation of GFAP protein]21863293
D003620DantroleneDantrolene inhibits the reaction [diphenylditelluride results in increased phosphorylation of GFAP protein]21879721
D003671DEET[DEET co-treated with Permethrin] results in increased expression of GFAP protein11681848
D003671DEETDEET results in increased expression of GFAP protein11681848
D013759DronabinolDronabinol results in decreased expression of GFAP mRNA21955143
D003907DexamethasoneDexamethasone results in increased expression of GFAP protein22048647
D003976DiazinonDiazinon affects the expression of GFAP mRNA17452286
D004026Dieldrin"Dieldrin promotes the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of GFAP protein]"16809432
D004051Diethylhexyl PhthalateDiethylhexyl Phthalate results in increased expression of GFAP protein28934723
D004052DiethylnitrosamineDiethylnitrosamine affects the expression of GFAP mRNA20387270
D004077DigoxinDigoxin results in increased expression of GFAP mRNA22954530
D002117CalcitriolCalcitriol affects the expression of GFAP mRNA15138306
D004117DimethoateDimethoate results in increased expression of GFAP mRNA21941777
D004117DimethoateDimethoate results in increased expression of GFAP protein21941777
D008559MemantineMemantine inhibits the reaction [Streptozocin results in increased expression of GFAP mRNA]24333387
D008559MemantineMemantine inhibits the reaction [Streptozocin results in increased expression of GFAP protein]24333387
C061132diphenyldiselenidediphenyldiselenide results in decreased expression of GFAP protein19926633
C434247diphenylditelluride"[1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester co-treated with Egtazic Acid] inhibits the reaction [diphenylditelluride results in increased phosphorylation of GFAP protein]"21879721
C434247diphenylditelluride"1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [diphenylditelluride results in increased phosphorylation of GFAP protein]"21879721
C434247diphenylditelluride2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [diphenylditelluride results in increased phosphorylation of GFAP protein]21879721
C434247diphenylditelluride"6-Cyano-7-nitroquinoxaline-2,3-dione inhibits the reaction [diphenylditelluride results in decreased phosphorylation of GFAP protein]"21863293
C434247diphenylditellurideCalcium affects the reaction [diphenylditelluride results in increased phosphorylation of GFAP protein]21879721
C434247diphenylditelluridecalyculin A inhibits the reaction [diphenylditelluride results in decreased phosphorylation of GFAP protein]21863293
C434247diphenylditellurideDantrolene inhibits the reaction [diphenylditelluride results in decreased phosphorylation of GFAP protein]21863293
C434247diphenylditellurideDantrolene inhibits the reaction [diphenylditelluride results in increased phosphorylation of GFAP protein]21879721
C434247diphenylditelluridediphenylditelluride results in decreased phosphorylation of GFAP protein21863293
C434247diphenylditelluridediphenylditelluride results in increased expression of GFAP mRNA22885153|2318294
C434247diphenylditelluridediphenylditelluride results in increased phosphorylation of and results in increased expression of GFAP protein23182946
C434247diphenylditelluridediphenylditelluride results in increased phosphorylation of GFAP protein21879721|2288515
C434247diphenylditellurideDizocilpine Maleate inhibits the reaction [diphenylditelluride results in decreased phosphorylation of GFAP protein]21863293
C434247diphenylditellurideExcitatory Amino Acid Antagonists inhibits the reaction [diphenylditelluride results in increased phosphorylation of GFAP protein]21879721
C434247diphenylditellurideFG 9041 inhibits the reaction [diphenylditelluride results in decreased phosphorylation of GFAP protein]21863293
C434247diphenylditellurideKN 93 inhibits the reaction [diphenylditelluride results in increased phosphorylation of GFAP protein]21879721
C434247diphenylditellurideNifedipine inhibits the reaction [diphenylditelluride results in decreased phosphorylation of GFAP protein]21863293
C434247diphenylditellurideStaurosporine inhibits the reaction [diphenylditelluride results in increased phosphorylation of GFAP protein]21879721
C434247diphenylditellurideVerapamil inhibits the reaction [diphenylditelluride results in decreased phosphorylation of GFAP protein]21863293
C434247diphenylditellurideVerapamil inhibits the reaction [diphenylditelluride results in increased phosphorylation of GFAP protein]21879721
D016291Dizocilpine MaleateDizocilpine Maleate inhibits the reaction [diphenylditelluride results in decreased phosphorylation of GFAP protein]21863293
D004317DoxorubicinDoxorubicin results in increased oxidation of GFAP protein28818578
C042986ebselenebselen results in increased phosphorylation of GFAP protein27282967
D004533Egtazic Acid"[1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester co-treated with Egtazic Acid] inhibits the reaction [diphenylditelluride results in increased phosphorylation of GFAP protein]"21879721
D000431EthanolEthanol results in increased expression of GFAP mRNA19460430
D000431EthanolEthanol results in increased expression of GFAP protein20621659
D000431EthanolEthanol results in decreased expression of GFAP mRNA21955143
D000431EthanolEthanol results in increased expression of GFAP protein23500890
D000431EthanolTLR4 gene mutant form inhibits the reaction [Ethanol results in increased expression of GFAP protein]23500890
D000431EthanolCalcium deficiency inhibits the reaction [Ethanol results in increased expression of GFAP protein]17888892
D000431EthanolEthanol affects the expression of GFAP protein17262233
D000431EthanolEthanol results in decreased expression of GFAP mRNA16770775|2083713
D000431EthanolEthanol results in decreased expression of GFAP protein16770775|2083713
D000431EthanolEthanol results in increased expression of GFAP protein17888892
D000431Ethanolresveratrol inhibits the reaction [Ethanol results in increased expression of GFAP protein]17888892
D000431EthanolCAT protein inhibits the reaction [Ethanol results in increased expression of GFAP protein]17888892
D004997Ethinyl EstradiolEthinyl Estradiol affects the expression of GFAP mRNA20227414
D004997Ethinyl EstradiolEthinyl Estradiol affects the expression of GFAP mRNA17555576
D004997Ethinyl Estradiol[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in decreased expression of GFAP mRNA17942748
D004997Ethinyl Estradiol[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of GFAP mRNA17942748
D018691Excitatory Amino Acid AntagonistsExcitatory Amino Acid Antagonists inhibits the reaction [diphenylditelluride results in increased phosphorylation of GFAP protein]21879721
C056723FG 9041FG 9041 inhibits the reaction [diphenylditelluride results in decreased phosphorylation of GFAP protein]21863293
D018120FinasterideFinasteride inhibits the reaction [Butyrates results in increased expression of GFAP mRNA]19360904
D018120FinasterideFinasteride inhibits the reaction [Butyrates results in increased expression of GFAP protein]19360904
D018120FinasterideFinasteride inhibits the reaction [Progesterone results in increased expression of GFAP mRNA]19360904
D018120FinasterideFinasteride inhibits the reaction [trichostatin A results in increased expression of GFAP mRNA]19360904
D018120FinasterideFinasteride inhibits the reaction [trichostatin A results in increased expression of GFAP protein]19360904
D018120FinasterideFinasteride inhibits the reaction [Valproic Acid results in increased expression of GFAP mRNA]19360904
D018120FinasterideFinasteride inhibits the reaction [Valproic Acid results in increased expression of GFAP protein]19360904
D005472FluorouracilFluorouracil results in increased expression of GFAP protein21296659
D005473FluoxetineFluoxetine results in increased expression of GFAP mRNA20857517
D005473FluoxetineFluoxetine results in increased expression of GFAP protein20857517
D005473FluoxetineGFAP protein results in increased susceptibility to Fluoxetine22113448
D005492Folic Acid[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of GFAP gene20938992
C039281furanfuran results in decreased expression of GFAP mRNA25539665
C039281furanfuran results in increased expression of GFAP mRNA25539665
C419708gefitinibgefitinib inhibits the reaction [HBEGF protein inhibits the reaction [sodium arsenite results in decreased expression of GFAP protein]]29228391
C004312glycidolglycidol results in decreased expression of GFAP mRNA24915197
C511402Grape Seed ProanthocyanidinsGrape Seed Proanthocyanidins affects the expression of GFAP protein16414080
D011745PyrithiaminePyrithiamine results in increased expression of GFAP protein27984051
D006861Hydrogen PeroxideHydrogen Peroxide results in increased expression of GFAP mRNA17997286
D006861Hydrogen PeroxideSodium Selenite inhibits the reaction [Hydrogen Peroxide results in increased expression of GFAP mRNA]17997286
D002112CalcifediolCalcifediol deficiency results in decreased expression of GFAP mRNA17293106
D007052IbuprofenIbuprofen inhibits the reaction [Streptozocin results in increased expression of GFAP mRNA]24333387
D007052IbuprofenIbuprofen inhibits the reaction [Streptozocin results in increased expression of GFAP protein]24333387
C082359imidaclopridimidacloprid results in increased expression of GFAP protein18080902
C040920isoliquiritigeninisoliquiritigenin inhibits the reaction [Methamphetamine results in increased expression of GFAP protein]19834288
D007608Kainic AcidEPO protein inhibits the reaction [Kainic Acid results in increased expression of GFAP protein]18711747
D007608Kainic AcidKainic Acid results in increased expression of GFAP mRNA17997037|2158991
D007608Kainic AcidKainic Acid results in increased expression of GFAP protein17997037
D007608Kainic AcidPTGS2 affects the reaction [Kainic Acid results in increased expression of GFAP mRNA]21589914
D007608Kainic AcidKainic Acid results in increased expression of GFAP mRNA19700661
D007608Kainic AcidKainic Acid results in increased expression of GFAP protein18711747|2279097
D007649KetamineKetamine results in increased expression of GFAP mRNA20080153
C072105KN 93KN 93 inhibits the reaction [diphenylditelluride results in increased phosphorylation of GFAP protein]21879721
D007854LeadLead results in decreased expression of GFAP mRNA25703175
D007854Leadtitanium dioxide promotes the reaction [Lead results in decreased expression of GFAP mRNA]25703175
D007854LeadLead affects the expression of GFAP mRNA28903495
C008261lead acetatelead acetate results in decreased expression of GFAP mRNA21868162
C008261lead acetatelead acetate results in increased expression of GFAP mRNA21322097
C008261lead acetate[Cadmium Chloride co-treated with sodium arsenite co-treated with lead acetate] results in decreased expression of GFAP protein20829427
C008261lead acetateCR8 compound inhibits the reaction [[sodium arsenite co-treated with lead acetate co-treated with Cadmium Chloride] results in decreased expression of GFAP protein]24481447
C008261lead acetate[lead acetate co-treated with Morphine] results in increased expression of GFAP mRNA26478469
C008261lead acetatelead acetate results in decreased expression of GFAP protein20829427
C008261lead acetatelead acetate results in increased expression of GFAP protein17047031
C008261lead acetate[sodium arsenite co-treated with Cadmium Chloride co-treated with lead acetate] results in increased expression of GFAP protein26396915
C008261lead acetate[sodium arsenite co-treated with lead acetate co-treated with Cadmium Chloride] promotes the reaction [PPARG protein binds to GFAP promoter]24481447
C008261lead acetate[sodium arsenite co-treated with lead acetate co-treated with Cadmium Chloride] results in decreased expression of GFAP mRNA24481447
C008261lead acetate[sodium arsenite co-treated with lead acetate co-treated with Cadmium Chloride] results in decreased expression of GFAP protein24481447
C008261lead acetate[[sodium arsenite co-treated with lead acetate co-treated with Cadmium Chloride] results in increased phosphorylation of and results in increased activity of PPARG protein] which results in decreased expression of GFAP protein24481447
C029891lead chloridelead chloride results in decreased expression of GFAP mRNA19651682
C017461lead nitrateAshwagandha inhibits the reaction [lead nitrate results in increased expression of GFAP mRNA]24987671
C017461lead nitrateAshwagandha inhibits the reaction [lead nitrate results in increased expression of GFAP protein]24987671
C017461lead nitratelead nitrate results in increased expression of GFAP mRNA24987671
C017461lead nitratelead nitrate results in increased expression of GFAP protein24987671
D008070LipopolysaccharidesLipopolysaccharides results in increased expression of GFAP protein12967722|1576399
D008070LipopolysaccharidesNFE2L2 protein affects the reaction [Probucol inhibits the reaction [Lipopolysaccharides results in increased expression of GFAP protein]]28881715
D008070LipopolysaccharidesProbucol inhibits the reaction [Lipopolysaccharides results in increased expression of GFAP protein]28881715
D008070Lipopolysaccharidestroglitazone inhibits the reaction [Lipopolysaccharides results in increased expression of GFAP protein]24481447
D018021Lithium ChlorideLithium Chloride inhibits the reaction [wogonin results in increased expression of GFAP protein]23872260
D018021Lithium ChlorideLithium Chloride inhibits the reaction [wogonin results in increased expression of GFAP protein]23872260
D047311LuteolinLuteolin inhibits the reaction [Carbon Tetrachloride results in increased expression of GFAP protein]19747501
C081064LY 231617LY 231617 affects the expression of GFAP mRNA8915593
C015329lycopenelycopene results in decreased expression of GFAP mRNA19555370
C005498magnololmagnolol inhibits the reaction [trimethyltin results in increased expression of GFAP protein]26756313
D008345ManganeseManganese results in increased expression of GFAP protein18284614
D008345ManganeseManganese results in increased expression of GFAP mRNA23832297
D008345ManganeseManganese results in increased expression of GFAP protein23832297
D008345ManganeseManganese affects the expression of GFAP protein24885898
D008345ManganeseManganese results in decreased expression of GFAP mRNA20224926
D008345ManganeseManganese results in increased expression of GFAP mRNA19782702|2022492
D008345ManganeseManganese results in increased expression of GFAP protein19782702
C025340manganese chloridemanganese chloride results in decreased expression of GFAP protein24969583
C025340manganese chloridemanganese chloride results in increased expression of GFAP protein25288107|2853924
C025340manganese chlorideMelatonin inhibits the reaction [manganese chloride results in increased expression of GFAP protein]25288107
C025340manganese chloridemanganese chloride results in decreased expression of GFAP protein12009774
C025340manganese chloridemanganese chloride results in increased expression of GFAP protein12106697|2406043
D008550MelatoninMelatonin inhibits the reaction [manganese chloride results in increased expression of GFAP protein]25288107
D008550MelatoninMelatonin inhibits the reaction [Carmustine results in decreased expression of GFAP protein]17572393
D008694Methamphetamineisoliquiritigenin inhibits the reaction [Methamphetamine results in increased expression of GFAP protein]19834288
D008694MethamphetamineMethamphetamine results in increased expression of GFAP mRNA12766323|2186774
D008694MethamphetamineMethamphetamine results in increased expression of GFAP protein15337264|1608894
D008694MethamphetamineRaclopride inhibits the reaction [Methamphetamine results in increased expression of GFAP protein]16088948
D008694MethamphetamineSCH 23390 inhibits the reaction [Methamphetamine results in increased expression of GFAP protein]16088948
D008694MethamphetamineSLC6A3 protein affects the reaction [Methamphetamine results in increased expression of GFAP mRNA]9634552
D008694MethamphetamineSLC6A3 protein affects the reaction [Methamphetamine results in increased expression of GFAP protein]9634552
D008694MethamphetamineTAAR1 protein affects the reaction [Methamphetamine results in increased expression of GFAP protein]28919515
D008694MethamphetamineMethamphetamine affects the expression of GFAP protein17262233
D008694MethamphetamineMethamphetamine results in increased expression of GFAP mRNA15644446
D008694MethamphetamineMethamphetamine results in increased expression of GFAP protein10773198|9427479
D008713MethimazoleMethimazole results in increased expression of GFAP protein22504374
D008715Methionine[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of GFAP gene20938992
D008717Methionine SulfoximineMethionine Sulfoximine results in increased expression of GFAP protein2565645
D008751Methylene BlueMethylene Blue inhibits the reaction [MAPT protein mutant form results in increased expression of GFAP mRNA]24556215
D008751Methylene BlueMethylene Blue inhibits the reaction [MAPT protein mutant form results in increased expression of GFAP protein]24556215
C004925methylmercuric chloridemethylmercuric chloride affects the expression of GFAP protein27012723
C004925methylmercuric chloridemethylmercuric chloride results in increased expression of GFAP mRNA22863855
C004925methylmercuric chloridemethylmercuric chloride results in increased expression of GFAP protein22863855
C004925methylmercuric chloridemethylmercuric chloride results in increased expression of GFAP mRNA27729293
C004925methylmercuric chloridemethylmercuric chloride results in increased expression of GFAP protein28821999
D008767Methylmercury CompoundsMethylmercury Compounds results in increased expression of GFAP mRNA21947502
D008767Methylmercury CompoundsMethylmercury Compounds promotes the reaction [CNTF protein results in increased expression of GFAP protein]23845766
D008767Methylmercury CompoundsMethylmercury Compounds results in increased expression of GFAP mRNA21628967
D008767Methylmercury CompoundsMethylmercury Compounds results in decreased expression of GFAP protein15288508
D018817N-Methyl-3,4-methylenedioxyamphetamine"Caffeine promotes the reaction [N-Methyl-3,4-methylenedioxyamphetamine results in increased expression of GFAP protein]"19882200
D018817N-Methyl-3,4-methylenedioxyamphetamine"N-Methyl-3,4-methylenedioxyamphetamine results in increased expression of GFAP protein"15337264|1988220
D018817N-Methyl-3,4-methylenedioxyamphetamine"N-Methyl-3,4-methylenedioxyamphetamine results in increased expression of GFAP protein"16489401
D008770MethylnitrosoureaMethylnitrosourea results in decreased expression of GFAP mRNA28688903
D008770MethylnitrosoureaMethylnitrosourea results in increased expression of GFAP protein18155124
D008743Methyl ParathionAtropine inhibits the reaction [Methyl Parathion results in decreased expression of GFAP mRNA]20826231
D008743Methyl ParathionMethyl Parathion results in decreased expression of GFAP mRNA20826231
D008743Methyl ParathionMethyl Parathion results in decreased expression of GFAP protein20826231
D0156551-Methyl-4-phenylpyridinium1-Methyl-4-phenylpyridinium results in increased expression of GFAP mRNA15140182
D0156321-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine"1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of GFAP protein"19199078|2374757
D0156321-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine"amentoflavone inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of GFAP protein]"28185818
D0156321-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine"benserazide, levodopa drug combination inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of GFAP protein]"28185818
D0156321-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine"CNB 001 inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of GFAP protein]"24995576
D0156321-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine"Dieldrin promotes the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of GFAP protein]"16809432
D0156321-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine"[Probenecid co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in increased expression of GFAP protein"25064079
D0156321-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine"telmisartan inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of GFAP protein]"23747572
D0156321-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine"Trehalose inhibits the reaction [[Probenecid co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in decreased expression of GFAP protein]"25064079
D0156321-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine"zonisamide inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of GFAP protein]"19199078
D008775MethylprednisoloneMethylprednisolone results in decreased expression of GFAP protein18509235
C078588microcystinmicrocystin analog results in increased degradation of GFAP protein27864109
C524165microcystin-LFmicrocystin-LF results in increased degradation of GFAP protein27864109
D052998MicrocystinsMicrocystins results in decreased expression of GFAP protein22430071
D016686MonocrotalineMonocrotaline affects the expression of GFAP protein21781985
C091888monoisoamyl-2,3-dimercaptosuccinate"monoisoamyl-2,3-dimercaptosuccinate results in decreased expression of GFAP mRNA"19615344
D009020MorphineMorphine results in decreased expression of GFAP mRNA21955143
D009020Morphine[lead acetate co-treated with Morphine] results in increased expression of GFAP mRNA26478469
C031448musk ketonemusk ketone results in increased expression of GFAP mRNA22954530
D009538NicotineNicotine results in decreased expression of GFAP mRNA21955143
D009538NicotineNicotine results in increased expression of GFAP mRNA17997037
D009543NifedipineNifedipine inhibits the reaction [diphenylditelluride results in decreased phosphorylation of GFAP protein]21863293
D009569Nitric OxideNitric Oxide deficiency results in decreased expression of GFAP protein15763998
C510003nordynordy results in increased expression of GFAP mRNA18232056
C510003nordynordy results in increased expression of GFAP protein16516855|1823205
C025589ochratoxin A"15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [ochratoxin A results in decreased expression of GFAP mRNA]"15994020
C025589ochratoxin A8-Bromo Cyclic Adenosine Monophosphate inhibits the reaction [ochratoxin A results in decreased expression of GFAP mRNA]15994020
C025589ochratoxin Aochratoxin A results in decreased expression of GFAP mRNA15994020|2295453
C025589ochratoxin Aochratoxin A results in decreased expression of GFAP protein24792326
C025589ochratoxin ASHH protein inhibits the reaction [ochratoxin A results in decreased expression of GFAP mRNA]24792326
D016627OxidopamineOxidopamine results in decreased expression of GFAP protein24486959
D016627OxidopamineOxidopamine results in increased expression of GFAP protein22842585
D016627Oxidopaminerosiglitazone promotes the reaction [Oxidopamine results in increased expression of GFAP protein]22842585
D0173718-Hydroxy-2-(di-n-propylamino)tetralin8-Hydroxy-2-(di-n-propylamino)tetralin inhibits the reaction [[Sarin co-treated with 2-(2-cresyl)-4H-1-3-2-benzodioxaphosphorin-2-oxide] results in increased expression of GFAP protein]23692952
C030110oxaliplatinoxaliplatin results in decreased expression of GFAP mRNA25729387
D010100OxygenOxygen results in increased expression of GFAP protein25203536
D010100Oxygen[Oxygen deficiency co-treated with Blood Glucose deficiency] results in increased expression of GFAP protein25727173
D010100Oxygenresveratrol inhibits the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in increased expression of GFAP protein]25727173
D017239PaclitaxelPaclitaxel results in increased expression of GFAP protein18098270
D017239Paclitaxel[Tretinoin co-treated with Paclitaxel] results in increased expression of GFAP protein18098270
D017239PaclitaxelPaclitaxel results in increased expression of GFAP protein16854522|1700517
D010269ParaquatParaquat results in increased expression of GFAP mRNA25314302
D010269ParaquatAPOD protein affects the reaction [Paraquat results in increased expression of GFAP protein]21688324
D010269ParaquatParaquat results in increased expression of GFAP protein21688324
D010269Paraquat[Paraquat results in increased abundance of Reactive Oxygen Species] which results in increased expression of GFAP protein24376630
D010269ParaquatParaquat results in increased expression of GFAP mRNA24521700|2846789
D010269ParaquatParaquat results in increased expression of GFAP protein24521700
D052638Particulate MatterParticulate Matter affects the expression of GFAP protein24690596
D052638Particulate MatterParticulate Matter results in increased expression of GFAP protein29121345
C086401pentabromodiphenyl etherpentabromodiphenyl ether results in increased expression of GFAP protein25616259
D010424PentobarbitalPentobarbital affects the expression of GFAP mRNA1317493
C076994perfluorooctane sulfonic acidperfluorooctane sulfonic acid results in increased expression of GFAP protein20937303
D026023PermethrinPermethrin results in increased expression of GFAP protein14555407
D026023Permethrin[Pyridostigmine Bromide co-treated with Permethrin] results in increased expression of GFAP protein27984134
D026023Permethrin[DEET co-treated with Permethrin] results in increased expression of GFAP protein11681848
D026023PermethrinPermethrin results in increased expression of GFAP protein11681848
D010622PhencyclidinePhencyclidine results in increased expression of GFAP mRNA17266109
D010643PhenoxybenzaminePhenoxybenzamine results in increased expression of GFAP protein17845906
C003121phosphinothricinphosphinothricin results in increased expression of GFAP mRNA27031874
C003121phosphinothricinphosphinothricin results in increased expression of GFAP protein27031874
D010798PhycocyaninPhycocyanin inhibits the reaction [tributyltin results in increased expression of GFAP protein]26079211
D010830PhysostigminePhysostigmine inhibits the reaction [Streptozocin results in decreased expression of GFAP protein]28499986
C004479pimagedine[7-nitroindazole co-treated with pimagedine] promotes the reaction [Capsaicin results in increased expression of GFAP protein]20826152
C004479pimagedine[7-nitroindazole co-treated with pimagedine] results in increased expression of GFAP protein20826152
C004479pimagedinepimagedine inhibits the reaction [Capsaicin results in increased expression of GFAP protein]20826152
D010936Plant ExtractsPlant Extracts results in decreased expression of GFAP mRNA23557933
D010936Plant ExtractsPlant Extracts results in increased expression of GFAP mRNA24677778
D011070Poly I-CPoly I-C results in increased expression of GFAP mRNA27317300
D045542PQQ CofactorPQQ Cofactor results in increased expression of GFAP mRNA28578007
D011339Probenecid"[Probenecid co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in increased expression of GFAP protein"25064079
D011339Probenecid"Trehalose inhibits the reaction [[Probenecid co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in decreased expression of GFAP protein]"25064079
D011341ProbucolNFE2L2 protein affects the reaction [Probucol inhibits the reaction [Lipopolysaccharides results in increased expression of GFAP protein]]28881715
D011341ProbucolProbucol inhibits the reaction [Lipopolysaccharides results in increased expression of GFAP protein]28881715
D011374Progesterone[Estradiol co-treated with Progesterone] promotes the reaction [Cuprizone results in increased expression of GFAP mRNA]19031445
D011374ProgesteroneProgesterone results in decreased expression of GFAP protein23157231
D011374ProgesteroneFinasteride inhibits the reaction [Progesterone results in increased expression of GFAP mRNA]19360904
D011374ProgesteroneProgesterone results in increased expression of GFAP mRNA19360904|2177076
D011374ProgesteroneProgesterone affects the expression of GFAP mRNA10987130
C029658propionic acidpropionic acid results in increased expression of GFAP protein16950524
D011441PropylthiouracilPropylthiouracil affects the expression of GFAP mRNA24780913
D011441PropylthiouracilPropylthiouracil results in increased expression of GFAP mRNA24780913
D011441PropylthiouracilPropylthiouracil results in increased expression of GFAP protein22504374
D011729Pyridostigmine Bromide[Pyridostigmine Bromide co-treated with Permethrin] results in increased expression of GFAP protein27984134
D020891RacloprideRaclopride inhibits the reaction [Methamphetamine results in increased expression of GFAP protein]16088948
D017382Reactive Oxygen Species[Paraquat results in increased abundance of Reactive Oxygen Species] which results in increased expression of GFAP protein24376630
C059514resveratrolresveratrol promotes the reaction [temozolomide results in increased expression of GFAP protein]22530672
C059514resveratrolresveratrol results in increased expression of GFAP protein22530672|2365158
C059514resveratroltemozolomide promotes the reaction [resveratrol results in increased expression of GFAP protein]22530672
C059514resveratrolresveratrol inhibits the reaction [CDK5R1 protein results in increased expression of GFAP protein]17581637
C059514resveratrolresveratrol inhibits the reaction [PPT1 gene mutant form results in increased expression of GFAP protein]21224254
C059514resveratrolresveratrol inhibits the reaction [Ethanol results in increased expression of GFAP protein]17888892
C059514resveratrolresveratrol inhibits the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in increased expression of GFAP protein]25727173
C059514resveratrolresveratrol results in decreased expression of GFAP protein27093858
C089032rimonabantrimonabant results in decreased expression of GFAP protein21373835
C089730rosiglitazone[rosiglitazone binds to and results in increased activity of PPARG protein] which results in decreased expression of GFAP mRNA18543250
C089730rosiglitazonerosiglitazone promotes the reaction [Oxidopamine results in increased expression of GFAP protein]22842585
C089730rosiglitazonerosiglitazone results in increased expression of GFAP protein24481447
D012402RotenoneRotenone results in increased expression of GFAP protein23098804
D012524SarinSarin results in decreased expression of GFAP protein25842371
D012524Sarin8-Hydroxy-2-(di-n-propylamino)tetralin inhibits the reaction [[Sarin co-treated with 2-(2-cresyl)-4H-1-3-2-benzodioxaphosphorin-2-oxide] results in increased expression of GFAP protein]23692952
D012524Sarin[Sarin co-treated with 2-(2-cresyl)-4H-1-3-2-benzodioxaphosphorin-2-oxide] results in increased expression of GFAP protein23692952
D012524SarinSarin results in increased expression of GFAP protein27639427
C429533SB 3CT compoundSB 3CT compound inhibits the reaction [sodium arsenite results in decreased expression of GFAP protein]29228391
C534628SCH 23390SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of GFAP protein]16088948
D012601Scopolamine Hydrobromide"6,7-epoxy-5,17-dihydroxy-1-oxowitha-2,24-dienolide inhibits the reaction [Scopolamine Hydrobromide results in decreased expression of GFAP protein]"22096544
D012601Scopolamine HydrobromideAshwagandha inhibits the reaction [Scopolamine Hydrobromide results in decreased expression of GFAP mRNA]22096544
D012601Scopolamine HydrobromideAshwagandha inhibits the reaction [Scopolamine Hydrobromide results in decreased expression of GFAP protein]22096544
D012601Scopolamine HydrobromideScopolamine Hydrobromide results in decreased expression of GFAP mRNA22096544
D012601Scopolamine HydrobromideScopolamine Hydrobromide results in decreased expression of GFAP protein22096544
D012834SilverSilver affects the expression of GFAP mRNA25976698
C017947sodium arsenitesodium arsenite results in decreased expression of GFAP mRNA19615344
C017947sodium arsenite[Cadmium Chloride co-treated with sodium arsenite co-treated with lead acetate] results in decreased expression of GFAP protein20829427
C017947sodium arseniteCR8 compound inhibits the reaction [[sodium arsenite co-treated with lead acetate co-treated with Cadmium Chloride] results in decreased expression of GFAP protein]24481447
C017947sodium arsenitegefitinib inhibits the reaction [HBEGF protein inhibits the reaction [sodium arsenite results in decreased expression of GFAP protein]]29228391
C017947sodium arseniteHBEGF protein inhibits the reaction [sodium arsenite results in decreased expression of GFAP protein]29228391
C017947sodium arseniteSB 3CT compound inhibits the reaction [sodium arsenite results in decreased expression of GFAP protein]29228391
C017947sodium arsenite[sodium arsenite co-treated with Cadmium Chloride co-treated with lead acetate] results in increased expression of GFAP protein26396915
C017947sodium arsenite[sodium arsenite co-treated with lead acetate co-treated with Cadmium Chloride] promotes the reaction [PPARG protein binds to GFAP promoter]24481447
C017947sodium arsenite[sodium arsenite co-treated with lead acetate co-treated with Cadmium Chloride] results in decreased expression of GFAP mRNA24481447
C017947sodium arsenite[sodium arsenite co-treated with lead acetate co-treated with Cadmium Chloride] results in decreased expression of GFAP protein24481447
C017947sodium arsenite[[sodium arsenite co-treated with lead acetate co-treated with Cadmium Chloride] results in increased phosphorylation of and results in increased activity of PPARG protein] which results in decreased expression of GFAP protein24481447
C017947sodium arsenitesodium arsenite results in decreased expression of GFAP mRNA29228391
C017947sodium arsenitesodium arsenite results in decreased expression of GFAP protein20829427|2922839
D012965Sodium ChlorideSodium Chloride results in decreased expression of GFAP protein16280599
D012965Sodium ChlorideSodium Chloride results in increased expression of GFAP mRNA22954530
D018038Sodium SeleniteSodium Selenite inhibits the reaction [Hydrogen Peroxide results in increased expression of GFAP mRNA]17997286
D018038Sodium SeleniteSodium Selenite results in decreased expression of GFAP mRNA18209489
D012999SomanSoman results in increased expression of GFAP mRNA19281266
D019311StaurosporineStaurosporine inhibits the reaction [diphenylditelluride results in increased phosphorylation of GFAP protein]21879721
D013311StreptozocinAcetylcysteine inhibits the reaction [Streptozocin results in decreased expression of GFAP protein]28499986
D013311StreptozocinPhysostigmine inhibits the reaction [Streptozocin results in decreased expression of GFAP protein]28499986
D013311StreptozocinStreptozocin results in decreased expression of GFAP protein28499986
D013311StreptozocinIbuprofen inhibits the reaction [Streptozocin results in increased expression of GFAP mRNA]24333387
D013311StreptozocinIbuprofen inhibits the reaction [Streptozocin results in increased expression of GFAP protein]24333387
D013311StreptozocinMemantine inhibits the reaction [Streptozocin results in increased expression of GFAP mRNA]24333387
D013311StreptozocinMemantine inhibits the reaction [Streptozocin results in increased expression of GFAP protein]24333387
D013311StreptozocinStreptozocin results in increased expression of GFAP mRNA24333387
D013311StreptozocinStreptozocin results in increased expression of GFAP protein24333387
D013331StrychnineStrychnine results in increased expression of GFAP mRNA22954530
C061133tamibarotenetamibarotene results in increased expression of GFAP19182380
D013629TamoxifenTamoxifen affects the expression of GFAP mRNA17555576
D013629TamoxifenTamoxifen inhibits the reaction [bisphenol A results in increased expression of GFAP protein]16860915
C021751tanshinonetanshinone results in increased expression of GFAP mRNA16955220
C021751tanshinonetanshinone results in increased expression of GFAP protein16955220
C084178telmisartan"telmisartan inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of GFAP protein]"23747572
C047246temozolomideresveratrol promotes the reaction [temozolomide results in increased expression of GFAP protein]22530672
C047246temozolomidetemozolomide promotes the reaction [resveratrol results in increased expression of GFAP protein]22530672
C047246temozolomidetemozolomide results in increased expression of GFAP protein22530672
D013726TerbutalineTerbutaline results in increased expression of GFAP protein14610225
D013739TestosteroneTestosterone results in decreased expression of GFAP mRNA19693291
D013739TestosteroneTestosterone affects the expression of GFAP mRNA10987130
C020806tetrabromobisphenol Atetrabromobisphenol A results in decreased expression of GFAP mRNA25172293
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of GFAP mRNA18343893
D013749Tetrachlorodibenzodioxin[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in decreased expression of GFAP mRNA17942748
D013749Tetrachlorodibenzodioxin[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of GFAP mRNA17942748
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased expression of GFAP mRNA19490992
D013750TetrachloroethyleneTetrachloroethylene results in decreased expression of GFAP protein8372046
D008063Thioctic AcidThioctic Acid results in decreased expression of GFAP mRNA19555370
C009495titanium dioxidetitanium dioxide promotes the reaction [Lead results in decreased expression of GFAP mRNA]25703175
D014050TolueneToluene results in increased expression of GFAP mRNA22166486
D014050TolueneToluene results in increased expression of GFAP protein10987130
D014199Trehalose"Trehalose inhibits the reaction [[Probenecid co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in decreased expression of GFAP protein]"25064079
D014212Tretinoin[Tretinoin co-treated with Paclitaxel] results in increased expression of GFAP protein18098270
D014212TretinoinTretinoin results in increased expression of GFAP mRNA23903816
D014212TretinoinTretinoin results in increased expression of GFAP protein17960384|1809827
D014212TretinoinTretinoin results in increased expression of GFAP mRNA11311979
D014212TretinoinTretinoin results in increased expression of GFAP protein11311979
D014212TretinoinTretinoin results in decreased expression of GFAP protein16944780
C009524tributyl phosphatetributyl phosphate results in decreased expression of GFAP mRNA27018022
C011559tributyltinPhycocyanin inhibits the reaction [tributyltin results in increased expression of GFAP protein]26079211
C011559tributyltintributyltin results in decreased expression of GFAP protein23743147
C011559tributyltintributyltin results in increased expression of GFAP protein23743147|2607921
C012589trichostatin Atrichostatin A results in decreased expression of GFAP mRNA15901671
C012589trichostatin AFinasteride inhibits the reaction [trichostatin A results in increased expression of GFAP mRNA]19360904
C012589trichostatin AFinasteride inhibits the reaction [trichostatin A results in increased expression of GFAP protein]19360904
C012589trichostatin Atrichostatin A results in increased expression of GFAP mRNA19360904
C012589trichostatin Atrichostatin A results in increased expression of GFAP protein19360904
C039474trimethylleadtrimethyllead affects the expression of GFAP8670008
C046488trimethyltintrimethyltin results in increased expression of GFAP mRNA27729293
C046488trimethyltinmagnolol inhibits the reaction [trimethyltin results in increased expression of GFAP protein]26756313
C046488trimethyltintrimethyltin results in increased expression of GFAP mRNA24002884
C046488trimethyltintrimethyltin results in increased expression of GFAP protein24002884|2675631
C013320tris(2-butoxyethyl) phosphatetris(2-butoxyethyl) phosphate results in decreased expression of GFAP mRNA27018022
C031324tris(chloroethyl)phosphatetris(chloroethyl)phosphate results in increased expression of GFAP mRNA27018022
C057693troglitazoneCR8 compound inhibits the reaction [troglitazone results in decreased expression of GFAP protein]24481447
C057693troglitazonetroglitazone inhibits the reaction [Lipopolysaccharides results in increased expression of GFAP protein]24481447
C057693troglitazonetroglitazone promotes the reaction [PPARG protein binds to GFAP promoter]24481447
C057693troglitazonetroglitazone results in decreased expression of GFAP mRNA24481447
C057693troglitazonetroglitazone results in decreased expression of GFAP protein24481447
C057693troglitazone[troglitazone results in increased phosphorylation of and results in increased activity of PPARG protein] which results in decreased expression of GFAP protein24481447
D014635Valproic AcidValproic Acid results in decreased expression of GFAP mRNA15901671
D014635Valproic AcidValproic Acid results in increased methylation of GFAP gene29154799
D014635Valproic AcidFinasteride inhibits the reaction [Valproic Acid results in increased expression of GFAP mRNA]19360904
D014635Valproic AcidFinasteride inhibits the reaction [Valproic Acid results in increased expression of GFAP protein]19360904
D014635Valproic AcidValproic Acid results in decreased expression of GFAP mRNA22954530
D014635Valproic AcidValproic Acid results in decreased expression of GFAP protein18585900
D014635Valproic AcidValproic Acid results in increased expression of GFAP mRNA19360904
D014635Valproic AcidValproic Acid results in increased expression of GFAP protein19360904
D000069470Venlafaxine HydrochlorideVenlafaxine Hydrochloride results in increased expression of GFAP mRNA25423262
D014700VerapamilVerapamil inhibits the reaction [diphenylditelluride results in decreased phosphorylation of GFAP protein]21863293
D014700VerapamilVerapamil inhibits the reaction [diphenylditelluride results in increased phosphorylation of GFAP protein]21879721
D014700VerapamilVerapamil results in increased expression of GFAP mRNA22954530
D014810Vitamin EVitamin E inhibits the reaction [Aluminum results in increased expression of GFAP protein]16545059
C085514wogoninLithium Chloride inhibits the reaction [wogonin results in increased expression of GFAP protein]23872260
C085514wogoninwogonin results in increased expression of GFAP protein23872260
C085514wogoninLithium Chloride inhibits the reaction [wogonin results in increased expression of GFAP protein]23872260
C085514wogoninwogonin results in increased expression of GFAP protein23872260
C085514wogoninDKK1 protein promotes the reaction [wogonin results in increased expression of GFAP protein]23872260
C022189zonisamide"zonisamide inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of GFAP protein]"19199078

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0005178integrin binding-IEA-  
GO:0005200structural constituent of cytoskeleton-IEA-  
GO:0005515protein binding-IPI16189514  25416956  25910212  26871637  27107014  
GO:0019900kinase binding-IEA-  
GO:0042802identical protein binding-IPI25416956  25910212  
GO ID GO Term Qualifier Evidence PubMed
GO:0009611response to wounding-IEA-  
GO:0010625positive regulation of Schwann cell proliferation-IEA-  
GO:0010977negative regulation of neuron projection development-IEA-  
GO:0014002astrocyte development-IEA-  
GO:0030198extracellular matrix organization-IEA-  
GO:0031102neuron projection regeneration-IEA-  
GO:0043254regulation of protein complex assembly-TAS20176123  
GO:0045109intermediate filament organization-IDA15732097  
GO:0051580regulation of neurotransmitter uptake-IEA-  
GO:0060020Bergmann glial cell differentiation-IEA-  
GO:0060291long-term synaptic potentiation-IEA-  
GO:1904714regulation of chaperone-mediated autophagy-ISS-  
GO:1904714regulation of chaperone-mediated autophagy-TAS20176123  
GO ID GO Term Qualifier Evidence PubMed
GO:0005737cytoplasm-IDA12355421  
GO:0005764lysosomecolocalizes_withISS-  
GO:0005829cytosol-TAS-  
GO:0005882intermediate filament-IEA-  
GO:0043209myelin sheath-IEA-  
GO:0044297cell body-IEA-  
GO:0097450astrocyte end-foot-IEA-  
GO:0098574cytoplasmic side of lysosomal membrane-IEA-  
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence
R-HSA-1236394Signaling by ERBB4TAS
R-HSA-1251985Nuclear signaling by ERBB4TAS
R-HSA-162582Signal TransductionTAS
R-HSA-9006934Signaling by Receptor Tyrosine KinasesTAS

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
28738332Neuroprogression and Immune Activation in Major Depressive Disorder. (2017)Meyer JHMod Trends Pharmacopsychiatry
15795061Maternal exposure of rats to nicotine via infusion during gestation produces neurobehavioral deficits and elevated expression of glial fibrillary acidic protein in the cerebellum and CA1 subfield in the offspring at puberty. (2005 May 5)Abdel-Rahman AToxicology
16385227The effect of ethanol on cell fate determination of neural stem cells. (2005 Dec)Tateno MAlcohol Clin Exp Res
28364101[Expression levels of ubiquitin C-terminal hydrolase-L1 and serum glial fibrillary acidic protein and its clinical significance in patients with acute cerebral infarction]. (2017 Mar 28)Hu CZhong Nan Da Xue Xue Bao Yi Xue Ban
27894930Sex-dependent influence of chronic mild stress (CMS) on voluntary alcohol consumption; study of neurobiological consequences. (2017 Jan)Marco EMPharmacol Biochem Behav
22797933Impact of opiate addiction on neuroinflammation in HIV. (2012 Oct)Byrd DJ Neurovirol
12488057Glia pathology in the prefrontal cortex in alcohol dependence with and without depressive symptoms. (2002 Dec 15)Miguel-Hidalgo JJBiol Psychiatry
28802862MicroRNA-21: Expression in oligodendrocytes and correlation with low myelin mRNAs in depression and alcoholism. (2017 Oct 3)Miguel-Hidalgo JJProg Neuropsychopharmacol Biol Psychiatry
10758340Cellular localization of serotonin(2A) (5HT(2A)) receptors in the rat brain. (2000 Apr)Xu TBrain Res Bull
15750888[Mechanisms of protein expression in the rat optic nerve. Modifications by alcohol exposure]. (2005 Feb)Pinazo-Duran MDArch Soc Esp Oftalmol
14555401Increased expression of glial fibrillary acidic protein in cerebellum and hippocampus: differential effects on neonatal brain regional acetylcholinesterase following maternal exposure to combined chlorpyrifos and nicotine. (2003 Nov 14)Abdel-Rahman AJ Toxicol Environ Health A
14668080Sex-selective hippocampal alterations after adolescent nicotine administration: effects on neurospecific proteins. (2003 Dec)Xu ZNicotine Tob Res
8247224GFAP mRNA increases with age in rat and human brain. (1993 Sep-Oct)Nichols NRNeurobiol Aging
29146238CCR5 mediates HIV-1 Tat-induced neuroinflammation and influences morphine tolerance, dependence, and reward. (2018 Mar)Gonek MBrain Behav Immun
17123717Yohimbine prevents morphine-induced changes of glial fibrillary acidic protein in brainstem and alpha2-adrenoceptor gene expression in hippocampus. (2007 Jan 29)Alonso ENeurosci Lett
25631712Role of Sigma Receptor in Cocaine-Mediated Induction of Glial Fibrillary Acidic Protein: Implications for HAND. (2016 Mar)Yang LMol Neurobiol
15897721Lower packing density of glial fibrillary acidic protein-immunoreactive astrocytes in the prelimbic cortex of alcohol-naive and alcohol-drinking alcohol-preferring rats as compared with alcohol-nonpreferring and Wistar rats. (2005 May)Miguel-Hidalgo JJAlcohol Clin Exp Res
26314629High postnatal susceptibility of hippocampal cytoskeleton in response to ethanol exposure during pregnancy and lactation. (2015 Nov)Reis KPAlcohol
20580095Glial and glutamatergic markers in depression, alcoholism, and their comorbidity. (2010 Dec)Miguel-Hidalgo JJJ Affect Disord
23192463Differential responses of hippocampal neurons and astrocytes to nicotine and hypoxia in the fetal guinea pig. (2013 Jul)Blutstein TNeurotox Res
16631170A low chronic ethanol exposure induces morphological changes in the adolescent rat brain that are not fully recovered even after a long abstinence: an immunohistochemical study. (2006 Aug)Evrard SGExp Neurol
29477594Morphological changes in the cerebellum as a result of ethanol treatment and cigarette smoke exposure: A study on astrogliosis, apoptosis and Purkinje cells. (2018 Apr 13)Wallauer MMNeurosci Lett