Gene: BBC3

27113
JFY-1|JFY1|PUMA
BCL2 binding component 3
protein-coding
19q13.32
Ensembl:ENSG00000105327 MIM:605854 Vega:OTTHUMG00000183489 UniprotKB:Q96PG8
NG_031991.1
PubMed
ND
1   
NA (AD)  NA (ND)   (Frontal_Cortex)
9.500e-1 (AD)  4.661e-1 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
LRFN10.797
DAPK30.797
RAC30.792
WDR240.792
ZNF8210.791
PHKG20.789
ASGR10.789
GPSM10.789
CAMSAP30.789
OGFR0.786

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
OR4F5-0.441
OR4F29-0.399
ARHGEF35-0.385
EBF1-0.384
C1orf87-0.38
MTRNR2L9-0.364
UPK1B-0.359
C9orf153-0.357
MTRNR2L10-0.357
PPBP-0.354

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C0264861,2,5,6-dibenzanthracene"1,2,5,6-dibenzanthracene results in increased expression of BBC3 mRNA"26377693
D0140131,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt"1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt inhibits the reaction [arsenic trioxide results in increased expression of BBC3 mRNA]"23892647
C0284741,4-bis(2-(3,5-dichloropyridyloxy))benzene"1,4-bis(2-(3,5-dichloropyridyloxy))benzene results in decreased expression of BBC3 mRNA"21354444|2269881
C5112952,2',4,4'-tetrabromodiphenyl ether"2,2',4,4'-tetrabromodiphenyl ether results in decreased expression of BBC3 mRNA"27589474
C5112952,2',4,4'-tetrabromodiphenyl ether"2,2',4,4'-tetrabromodiphenyl ether results in increased expression of BBC3 mRNA"27589474
C4512192,2-bis(hydroxymethyl)-1-azabicyclo(2,2,2,)octan-3-one"2,2-bis(hydroxymethyl)-1-azabicyclo(2,2,2,)octan-3-one promotes the reaction [Cisplatin results in increased expression of BBC3 mRNA]"21109480
C0140242,4,5,2',4',5'-hexachlorobiphenyl"2,4,5,2',4',5'-hexachlorobiphenyl inhibits the reaction [Benzo(a)pyrene results in increased expression of BBC3 protein]"24954032
C0140242,4,5,2',4',5'-hexachlorobiphenyl"2,4,5,2',4',5'-hexachlorobiphenyl inhibits the reaction [dibenzo(a,l)pyrene affects the expression of BBC3 protein]"24954032
C0140242,4,5,2',4',5'-hexachlorobiphenyl"Okadaic Acid inhibits the reaction [2,4,5,2',4',5'-hexachlorobiphenyl inhibits the reaction [Benzo(a)pyrene results in increased expression of BBC3 protein]]"24954032
C5290612-(4,5-dihydro-1,3-thiazol-2-ylthio)-1-(3,4-dihydroxyphenyl)ethanone"TP53 protein mutant form affects the reaction [2-(4,5-dihydro-1,3-thiazol-2-ylthio)-1-(3,4-dihydroxyphenyl)ethanone results in increased expression of BBC3 mRNA]"18424558
C0859112-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one[Doxorubicin co-treated with 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one] results in increased expression of BBC3 protein20856197
C0859112-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-oneTP53 protein promotes the reaction [[Doxorubicin co-treated with 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one] results in increased expression of BBC3 protein]20856197
C0859112-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in increased expression of BBC3 protein24567336
C0163923,3'-diindolylmethane"[3,3'-diindolylmethane results in increased phosphorylation of and results in increased activity of TP53 protein] which results in increased expression of BBC3"22290291
C4727913-(4'-hydroxy-3'-adamantylbiphenyl-4-yl)acrylic acid3-(4'-hydroxy-3'-adamantylbiphenyl-4-yl)acrylic acid results in increased expression of BBC3 mRNA16788091
C0179063-dinitrobenzene3-dinitrobenzene results in increased expression of BBC3 mRNA22841810|2414075
C0275764-hydroxy-2-nonenal4-hydroxy-2-nonenal results in increased expression of BBC3 mRNA24291486
C0275764-hydroxy-2-nonenal4-phenylbutylamine inhibits the reaction [4-hydroxy-2-nonenal results in increased expression of BBC3 mRNA]24291486
C0275764-hydroxy-2-nonenalAcetylcysteine inhibits the reaction [4-hydroxy-2-nonenal results in increased expression of BBC3 mRNA]24291486
C0789564-methylthioamphetamine4-methylthioamphetamine results in increased expression of BBC3 mRNA23820845
C0789564-methylthioamphetamine4-methylthioamphetamine results in increased expression of BBC3 protein23820845
C0789564-methylthioamphetamine"[N-Methyl-3,4-methylenedioxyamphetamine co-treated with Methamphetamine co-treated with 4-methylthioamphetamine co-treated with Dextroamphetamine] results in increased expression of BBC3 mRNA"23820845
C0789564-methylthioamphetamine"[N-Methyl-3,4-methylenedioxyamphetamine co-treated with Methamphetamine co-treated with 4-methylthioamphetamine co-treated with Dextroamphetamine] results in increased expression of BBC3 protein"23820845
C1213584-phenylbutylamine4-phenylbutylamine inhibits the reaction [4-hydroxy-2-nonenal results in increased expression of BBC3 mRNA]24291486
C5805985-OH-BDE-475-OH-BDE-47 results in decreased expression of BBC3 mRNA27589474
C5505476-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide"6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [resveratrol inhibits the reaction [Cisplatin results in increased expression of BBC3 protein]]"21593185
C5505476-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide"pifithrin inhibits the reaction [6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [resveratrol inhibits the reaction [Cisplatin results in increased expression of BBC3 protein]]]"21593185
C5805996-OH-BDE-476-OH-BDE-47 results in decreased expression of BBC3 mRNA27589474
C0053999,10-phenanthrenequinone"9,10-phenanthrenequinone results in increased expression of BBC3 protein"29108775
C011651acadesineacadesine results in increased expression of BBC3 protein20664053
D000082AcetaminophenAcetaminophen results in decreased expression of BBC3 mRNA26690555
D000082AcetaminophenAcetaminophen affects the expression of BBC3 mRNA17562736
C487680acetylbritannilatoneacetylbritannilatone analog results in increased expression of BBC3 mRNA27262408
C487680acetylbritannilatoneTP53 protein affects the reaction [acetylbritannilatone analog results in increased expression of BBC3 mRNA]27262408
D000111AcetylcysteineAcetylcysteine inhibits the reaction [4-hydroxy-2-nonenal results in increased expression of BBC3 mRNA]24291486
D016604Aflatoxin B1Aflatoxin B1 results in increased expression of BBC3 mRNA21641981
D003913DextroamphetamineDextroamphetamine results in increased expression of BBC3 mRNA23820845
D003913DextroamphetamineDextroamphetamine results in increased expression of BBC3 protein23820845
D003913Dextroamphetamine"[N-Methyl-3,4-methylenedioxyamphetamine co-treated with Methamphetamine co-treated with 4-methylthioamphetamine co-treated with Dextroamphetamine] results in increased expression of BBC3 mRNA"23820845
D003913Dextroamphetamine"[N-Methyl-3,4-methylenedioxyamphetamine co-treated with Methamphetamine co-treated with 4-methylthioamphetamine co-treated with Dextroamphetamine] results in increased expression of BBC3 protein"23820845
C540917anthraceno(1,2-c)(1,2,5)selenadiazolo-6,11-dione"anthraceno(1,2-c)(1,2,5)selenadiazolo-6,11-dione results in increased expression of BBC3 protein"19146838
C006632arsenic trioxidearsenic trioxide results in decreased expression of BBC3 protein20723298
C006632arsenic trioxidearsenic trioxide results in increased expression of BBC3 mRNA24345465
C006632arsenic trioxidearsenic trioxide results in increased expression of BBC3 protein17374990|2145452
C006632arsenic trioxide[sanguinarine co-treated with arsenic trioxide] results in increased expression of BBC3 mRNA24345465
C006632arsenic trioxide"1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt inhibits the reaction [arsenic trioxide results in increased expression of BBC3 mRNA]"23892647
C006632arsenic trioxidearsenic trioxide results in increased expression of BBC3 mRNA23892647
C006632arsenic trioxideThioctic Acid inhibits the reaction [arsenic trioxide results in increased expression of BBC3 mRNA]23892647
C015001arsenitearsenite results in increased expression of BBC3 protein20083129
D001194AsbestosAsbestos results in decreased expression of BBC327042963
D001205Ascorbic Acid[Ascorbic Acid co-treated with Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of BBC3 protein20530418
D001205Ascorbic Acidbenzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[Ascorbic Acid co-treated with Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of BBC3 protein]20530418
D001241AspirinAspirin results in increased expression of BBC3 mRNA19936928
D001241AspirinBBC3 results in increased susceptibility to Aspirin19936928
D001280AtrazineAtrazine results in increased expression of BBC3 mRNA22378314
C072019benzo(a)pyrene diolepoxide Ibenzo(a)pyrene diolepoxide I results in increased expression of BBC3 mRNA27694624
D001564Benzo(a)pyrene"2,4,5,2',4',5'-hexachlorobiphenyl inhibits the reaction [Benzo(a)pyrene results in increased expression of BBC3 protein]"24954032
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of BBC3 mRNA20064835|2139335
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of BBC3 protein24954032
D001564Benzo(a)pyreneEstradiol inhibits the reaction [Benzo(a)pyrene results in increased expression of BBC3 protein]24954032
D001564Benzo(a)pyrenefostriecin inhibits the reaction [Tetrachlorodibenzodioxin inhibits the reaction [Benzo(a)pyrene results in increased expression of BBC3 protein]]24954032
D001564Benzo(a)pyrene"Okadaic Acid inhibits the reaction [2,4,5,2',4',5'-hexachlorobiphenyl inhibits the reaction [Benzo(a)pyrene results in increased expression of BBC3 protein]]"24954032
D001564Benzo(a)pyreneOkadaic Acid inhibits the reaction [Estradiol inhibits the reaction [Benzo(a)pyrene results in increased expression of BBC3 protein]]24954032
D001564Benzo(a)pyreneOkadaic Acid inhibits the reaction [Tetrachlorodibenzodioxin inhibits the reaction [Benzo(a)pyrene results in increased expression of BBC3 protein]]24954032
D001564Benzo(a)pyreneTetrachlorodibenzodioxin inhibits the reaction [Benzo(a)pyrene results in increased expression of BBC3 protein]24954032
D001564Benzo(a)pyreneBenzo(a)pyrene results in decreased expression of BBC3 mRNA27195522
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of BBC3 mRNA19770486|2156981
D0151237,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide"7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased expression of BBC3 mRNA"26238291|2859349
C072553benzyloxycarbonylleucyl-leucyl-leucine aldehydebenzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[Ascorbic Acid co-treated with Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of BBC3 protein]20530418
D001599Berberine[Berberine co-treated with Niacinamide] results in increased expression of BBC3 mRNA26712469
D001599BerberineBerberine results in increased expression of BBC3 mRNA26712469
D004958EstradiolEstradiol inhibits the reaction [Benzo(a)pyrene results in increased expression of BBC3 protein]24954032
D004958Estradiol"Estradiol inhibits the reaction [dibenzo(a,l)pyrene affects the expression of BBC3 protein]"24954032
D004958EstradiolEstradiol results in decreased expression of BBC3 mRNA25321415
D004958EstradiolEstradiol results in increased expression of BBC3 mRNA23373633
D004958EstradiolOkadaic Acid inhibits the reaction [Estradiol inhibits the reaction [Benzo(a)pyrene results in increased expression of BBC3 protein]]24954032
D004958EstradiolEstradiol results in decreased expression of BBC3 mRNA22467019
C006780bisphenol Abisphenol A results in increased expression of BBC3 mRNA27685785
C006780bisphenol Abisphenol A results in increased expression of BBC3 mRNA25181051
D000069286BortezomibBortezomib results in increased expression of BBC3 mRNA20051518
D000069286BortezomibBortezomib results in increased expression of BBC3 protein17898295|2005151
D002110CaffeineCaffeine inhibits the reaction [kaempferol results in increased expression of BBC3 protein]19028473
D002166CamptothecinBBC3 protein affects the susceptibility to Camptothecin20477944
C006698carbendazimcarbendazim affects the expression of BBC3 mRNA25304545|2605522
D000068579CelecoxibBBC3 mutant form inhibits the reaction [Celecoxib results in increased activity of and results in increased localization of BAX protein]17368424
D000068579CelecoxibBBC3 results in increased susceptibility to Celecoxib17368424
D000068579CelecoxibCelecoxib results in increased expression of BBC317368424
D000068579CelecoxibCelecoxib results in increased expression of BBC3 protein18760266
D000068579CelecoxibTP53 protein promotes the reaction [Celecoxib results in increased expression of BBC3 protein]18760266
D002699ChlorambucilChlorambucil results in increased expression of BBC3 mRNA17476690
C004656chloroacetaldehydechloroacetaldehyde results in increased expression of BBC3 mRNA25596134
D002791Cholesterol, Dietary"Cholesterol, Dietary results in increased expression of BBC3 mRNA"27239252
D002791Cholesterol, Dietary"Rutin inhibits the reaction [Cholesterol, Dietary results in increased expression of BBC3 mRNA]"27239252
D002794Choline[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of BBC3 gene20938992
D002857ChromiumChromium promotes the reaction [TP53 protein binds to BBC3 promoter]18602874
D002857ChromiumChromium results in increased expression of BBC3 mRNA18602874
C074702chromium hexavalent ionchromium hexavalent ion results in increased expression of BBC3 protein16166740
C074702chromium hexavalent ionTP53 protein affects the reaction [chromium hexavalent ion results in increased expression of BBC3 protein]16166740
C059262cidofovircidofovir results in increased expression of BBC3 mRNA25596134
D002922CiguatoxinsCiguatoxins affects the expression of BBC3 mRNA18353800
D003035CobaltCobalt results in increased expression of BBC3 mRNA24068677
D003035CobaltTP53 protein affects the reaction [Cobalt results in increased expression of BBC3 mRNA]24068677
D003035Cobalt[tungsten carbide co-treated with Cobalt] results in increased expression of BBC3 mRNA18078969
C018021cobaltous chloride[cobaltous chloride co-treated with TP53 gene mutant form] results in decreased expression of BBC3 protein21687937
C018021cobaltous chloridecobaltous chloride inhibits the reaction [[Doxorubicin results in increased phosphorylation of and results in increased activity of TP53 protein] which results in increased expression of BBC3 mRNA]19714248
C018021cobaltous chloridecobaltous chloride results in increased expression of BBC3 mRNA19376846
C018021cobaltous chloridecobaltous chloride results in increased expression of BBC3 protein21687937|2338047
D003300CopperCopper results in increased expression of BBC3 mRNA16391388
D019327Copper SulfateCopper Sulfate results in increased expression of BBC3 mRNA19549813
D003474CurcuminCurcumin results in increased expression of BBC3 mRNA17332930
D003474CurcuminCurcumin results in decreased expression of BBC3 mRNA22714040
C017160cypermethrincypermethrin results in increased expression of BBC3 mRNA21316461
D003561CytarabineBBC3 protein affects the susceptibility to Cytarabine20477944
D003609DactinomycinDactinomycin results in increased expression of BBC3 mRNA17581298
D003609DactinomycinDactinomycin results in increased expression of BBC3 protein17581298
C014347decitabine[decitabine affects the methylation of BBC3 gene] which affects the expression of BBC3 mRNA18573879|1857387
C014347decitabine[decitabine affects the methylation of BBC3 gene] which affects the expression of BBC3 protein18573879|1857387
C014347decitabinedecitabine affects the methylation of BBC3 promoter17488656
C014347decitabinedecitabine results in increased expression of BBC3 protein19732952
C007262deoxynivalenoldeoxynivalenol results in increased expression of BBC3 mRNA22846391
D003907DexamethasoneDexamethasone inhibits the reaction [RX3 gene mutant form affects the expression of BBC3 mRNA]27941970
D003907DexamethasoneDexamethasone results in decreased expression of BBC3 mRNA25047013
D003907DexamethasoneDexamethasone results in increased expression of BBC3 mRNA22733784
C042577diallyl trisulfidediallyl trisulfide results in increased expression of BBC3 mRNA24460275
C042577diallyl trisulfidediallyl trisulfide results in increased expression of BBC3 protein24460275
D003976DiazinonDiazinon affects the expression of BBC3 mRNA22546817
C041517dibenzo(a,l)pyrene"2,4,5,2',4',5'-hexachlorobiphenyl inhibits the reaction [dibenzo(a,l)pyrene affects the expression of BBC3 protein]"24954032
C041517dibenzo(a,l)pyrene"dibenzo(a,l)pyrene affects the expression of BBC3 protein"24954032
C041517dibenzo(a,l)pyrene"Estradiol inhibits the reaction [dibenzo(a,l)pyrene affects the expression of BBC3 protein]"24954032
C041517dibenzo(a,l)pyrene"Tetrachlorodibenzodioxin inhibits the reaction [dibenzo(a,l)pyrene affects the expression of BBC3 protein]"24954032
C041517dibenzo(a,l)pyrene"dibenzo(a,l)pyrene results in increased expression of BBC3 mRNA"26496743
D003993Dibutyl PhthalateDibutyl Phthalate results in increased expression of BBC3 mRNA17361019|2126653
D003999Dichloroacetic AcidDichloroacetic Acid results in increased expression of BBC3 mRNA22705712
D002945Cisplatin"2,2-bis(hydroxymethyl)-1-azabicyclo(2,2,2,)octan-3-one promotes the reaction [Cisplatin results in increased expression of BBC3 mRNA]"21109480
D002945CisplatinBBC3 protein results in increased susceptibility to Cisplatin16481741|2153299
D002945CisplatinCisplatin inhibits the reaction [[HDAC1 protein co-treated with TP63 protein modified form] binds to BBC3 promoter]21527555
D002945CisplatinCisplatin promotes the reaction [TP53 protein results in increased expression of BBC3 mRNA]21532991
D002945CisplatinCisplatin results in increased expression of BBC3 mRNA16481741|2110948
D002945CisplatinCisplatin results in increased expression of BBC3 protein16481741|2128535
D002945CisplatinMSH2 protein promotes the reaction [Cisplatin results in increased expression of BBC3 protein]21285353
D002945Cisplatinnutlin 3 promotes the reaction [Cisplatin results in increased expression of BBC3 mRNA]21109480
D002945Cisplatin[[Sirolimus co-treated with Cisplatin] results in increased expression of TP73 protein] which results in increased expression of BBC3 protein20686837
D002945CisplatinTP73 protein modified form promotes the reaction [Cisplatin results in increased expression of BBC3 protein]21516125
D002945CisplatinTretinoin inhibits the reaction [Cisplatin results in increased expression of BBC3 mRNA]21532991
D002945Cisplatin"6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [resveratrol inhibits the reaction [Cisplatin results in increased expression of BBC3 protein]]"21593185
D002945CisplatinBBC3 protein affects the susceptibility to Cisplatin20477944
D002945CisplatinCisplatin results in increased expression of BBC3 protein21285353|2159318
D002945Cisplatinerdosteine inhibits the reaction [Cisplatin results in increased expression of BBC3 protein]26193055
D002945CisplatinMSH2 protein promotes the reaction [Cisplatin results in increased expression of BBC3 protein]21285353
D002945Cisplatin"pifithrin inhibits the reaction [6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [resveratrol inhibits the reaction [Cisplatin results in increased expression of BBC3 protein]]]"21593185
D002945Cisplatinresveratrol inhibits the reaction [Cisplatin results in increased expression of BBC3 protein]21593185
D002945CisplatinSB 216763 inhibits the reaction [Cisplatin results in increased expression of BBC3 protein]24560772
D002945CisplatinCisplatin results in increased expression of BBC3 protein20650967
D004026DieldrinDieldrin affects the expression of BBC3 mRNA22546817
D004041Dietary FatsDietary Fats results in increased expression of BBC3 mRNA18042831
C558638DLBS 1425DLBS 1425 results in increased expression of BBC3 mRNA20703095
D004298Dopamine[Dopamine results in increased expression of HIF1A protein] which results in increased expression of BBC3 mRNA19410601
D004298Dopamine[Dopamine results in increased expression of HIF1A protein] which results in increased expression of BBC3 protein19410601
D004317Doxorubicincobaltous chloride inhibits the reaction [[Doxorubicin results in increased phosphorylation of and results in increased activity of TP53 protein] which results in increased expression of BBC3 mRNA]19714248
D004317Doxorubicin[Doxorubicin co-treated with 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one] results in increased expression of BBC3 protein20856197
D004317Doxorubicin[Doxorubicin co-treated with PI103] results in increased expression of BBC3 protein20856197
D004317DoxorubicinDoxorubicin promotes the reaction [[TP53 protein binds to BBC3 promoter] which results in increased expression of BBC3 mRNA]19714248|1971424
D004317DoxorubicinDoxorubicin results in increased expression of BBC3 mRNA16439685
D004317DoxorubicinDoxorubicin results in increased expression of BBC3 protein20856197|2481618
D004317Doxorubicin[Doxorubicin results in increased phosphorylation of and results in increased activity of TP53 protein] which results in increased expression of BBC3 mRNA19714248
D004317DoxorubicinTP53 protein mutant form affects the reaction [Doxorubicin results in increased expression of BBC3 protein]24816189
D004317DoxorubicinTP53 protein promotes the reaction [[Doxorubicin co-treated with 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one] results in increased expression of BBC3 protein]20856197
D004317DoxorubicinTP53 protein promotes the reaction [[Doxorubicin co-treated with PI103] results in increased expression of BBC3 protein]20856197
D004317DoxorubicinDoxorubicin results in increased expression of BBC3 mRNA16018998
D004317Doxorubicinzinc chloride promotes the reaction [Doxorubicin results in increased expression of BBC3 mRNA]19714248
D004317DoxorubicinDoxorubicin results in increased expression of BBC3 mRNA27181935
D004317DoxorubicinDoxorubicin results in increased expression of BBC3 protein18775851
D004317DoxorubicinFungal Polysaccharides inhibits the reaction [Doxorubicin results in increased expression of BBC3 mRNA]27181935
D004317Doxorubicinpifithrin inhibits the reaction [Doxorubicin results in increased expression of BBC3 protein]18775851
D004317DoxorubicinU 0126 inhibits the reaction [Doxorubicin results in increased expression of BBC3 protein]18775851
D004365Drugs, Chinese Herbal"Drugs, Chinese Herbal results in increased expression of BBC3 mRNA"23811387
C118739entinostatentinostat promotes the reaction [Etoposide results in increased expression of BBC3 protein]25699604
C118739entinostatentinostat results in increased expression of BBC3 protein25699604
C118739entinostatEtoposide promotes the reaction [entinostat results in increased expression of BBC3 protein]25699604
C048498erdosteineerdosteine inhibits the reaction [Cisplatin results in increased expression of BBC3 protein]26193055
D000069347Erlotinib HydrochlorideErlotinib Hydrochloride promotes the reaction [resveratrol results in increased expression of BBC3 protein]25895606
D000069347Erlotinib HydrochlorideErlotinib Hydrochloride results in increased expression of BBC3 protein25895606
D000069347Erlotinib Hydrochlorideresveratrol promotes the reaction [Erlotinib Hydrochloride results in increased expression of BBC3 protein]25895606
D000431EthanolEthanol results in increased expression of BBC3 protein27270636
D000431EthanolSIAH1 protein promotes the reaction [Ethanol results in increased expression of BBC3 protein]27270636
D004997Ethinyl EstradiolEthinyl Estradiol results in increased expression of BBC3 mRNA17942748
D004997Ethinyl Estradiol[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of BBC3 mRNA17942748
D005020Ethyl MethanesulfonateEthyl Methanesulfonate results in increased expression of BBC3 mRNA23649840
D005047Etoposideentinostat promotes the reaction [Etoposide results in increased expression of BBC3 protein]25699604
D005047EtoposideEtoposide promotes the reaction [entinostat results in increased expression of BBC3 protein]25699604
D005047EtoposideEtoposide promotes the reaction [trichostatin A results in increased expression of BBC3 protein]25699604
D005047EtoposideEtoposide promotes the reaction [UF010 compound results in increased expression of BBC3 protein]25699604
D005047EtoposideEtoposide results in increased expression of BBC3 mRNA21801448
D005047EtoposideEtoposide results in increased expression of BBC3 protein25699604
D005047Etoposidetrichostatin A promotes the reaction [Etoposide results in increased expression of BBC3 protein]25699604
D005047EtoposideUF010 compound promotes the reaction [Etoposide results in increased expression of BBC3 protein]25699604
D005047EtoposideBBC3 protein affects the susceptibility to Etoposide20477944
C020326ferric nitrilotriacetateferric nitrilotriacetate results in increased expression of BBC3 mRNA23208426
D005411Flame RetardantsFlame Retardants results in increased expression of BBC3 mRNA19356805
C024352fludarabinefludarabine results in increased expression of BBC3 mRNA16439685
D005472FluorouracilBBC3 protein results in increased susceptibility to Fluorouracil16481741
D005472FluorouracilFluorouracil results in increased expression of BBC3 mRNA16481741|1655759
D005472FluorouracilFluorouracil results in increased expression of BBC3 protein14665630|1548989
D005472Fluorouracilmithramycin A inhibits the reaction [Fluorouracil results in increased expression of BBC3 protein]15489892
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in increased expression of BBC3 mRNA]15016801
D005472FluorouracilTP53 protein affects the reaction [Fluorouracil results in increased expression of BBC3 protein]14665630
D005492Folic Acid[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of BBC3 gene20938992
D005557FormaldehydeFormaldehyde results in increased expression of BBC3 mRNA23649840
C040313fostriecinfostriecin inhibits the reaction [Tetrachlorodibenzodioxin inhibits the reaction [Benzo(a)pyrene results in increased expression of BBC3 protein]]24954032
D062610Fungal PolysaccharidesFungal Polysaccharides inhibits the reaction [Doxorubicin results in increased expression of BBC3 mRNA]27181935
D005839GentamicinsGentamicins results in increased expression of BBC3 mRNA22061828
C040155geranylgeranic acidgeranylgeranic acid results in increased expression of BBC3 mRNA24658405
C040155geranylgeranic acidIvermectin inhibits the reaction [geranylgeranic acid results in increased expression of BBC3 mRNA]24658405
D005947Glucose[Palmitic Acid co-treated with Glucose] results in increased expression of BBC3 mRNA24451382
D005947GlucoseSIRT1 protein mutant form inhibits the reaction [[Palmitic Acid co-treated with Glucose] results in increased expression of BBC3 mRNA]24451382
D005947Glucose[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of BBC3 protein modified form28675767
D005947GlucoseSIRT7 protein inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of BBC3 protein]28675767
D006072GossypolGossypol results in increased expression of BBC3 protein18840529
C042349heminordihydroguaiaretic acidheminordihydroguaiaretic acid results in increased expression of BBC3 protein17393435
C089796hexabromocyclododecanehexabromocyclododecane results in increased expression of BBC3 mRNA19356805
D017313FenretinideBBC3 protein results in increased susceptibility to Fenretinide16091745
D017313FenretinideFenretinide results in increased expression of BBC3 mRNA16091745
D017313FenretinideFenretinide results in increased expression of BBC3 protein16091745
D006861Hydrogen PeroxideHydrogen Peroxide affects the expression of BBC3 mRNA20044591
D006861Hydrogen PeroxideBBC3 protein affects the susceptibility to Hydrogen Peroxide20477944
C031927hydroquinonehydroquinone results in increased expression of BBC3 mRNA23416264
D006918HydroxyureaHydroxyurea results in increased expression of BBC3 mRNA27208086
C559745hyperforin dicyclohexylammoniumhyperforin dicyclohexylammonium results in increased expression of BBC3 protein21376709
D007559IvermectinIvermectin inhibits the reaction [geranylgeranic acid results in increased expression of BBC3 mRNA]24658405
C410337K 7174K 7174 results in increased expression of BBC3 mRNA24086573
C006552kaempferolCaffeine inhibits the reaction [kaempferol results in increased expression of BBC3 protein]19028473
C006552kaempferolkaempferol promotes the reaction [BBC3 protein binds to BCL2L1 protein]19028473
C006552kaempferolkaempferol results in increased expression of BBC3 protein19028473
C006552kaempferolTP53 protein affects the reaction [kaempferol promotes the reaction [BBC3 protein binds to BCL2L1 protein]]19028473
D008344ManebManeb results in increased expression of BBC3 protein18266926
D008694MethamphetamineBBC3 protein affects the reaction [Methamphetamine results in decreased cleavage of CASP3 protein]26524635
D008694MethamphetamineBBC3 protein affects the reaction [Methamphetamine results in decreased cleavage of PARP1 protein]26524635
D008694MethamphetamineBBC3 protein affects the reaction [Methamphetamine results in decreased expression of BCL2 protein]26524635
D008694MethamphetamineBBC3 protein affects the reaction [Methamphetamine results in increased expression of BAX protein]26524635
D008694MethamphetamineMethamphetamine results in increased expression of BBC3 mRNA23820845
D008694MethamphetamineMethamphetamine results in increased expression of BBC3 protein23820845|2652463
D008694Methamphetamine"[N-Methyl-3,4-methylenedioxyamphetamine co-treated with Methamphetamine co-treated with 4-methylthioamphetamine co-treated with Dextroamphetamine] results in increased expression of BBC3 mRNA"23820845
D008694Methamphetamine"[N-Methyl-3,4-methylenedioxyamphetamine co-treated with Methamphetamine co-treated with 4-methylthioamphetamine co-treated with Dextroamphetamine] results in increased expression of BBC3 protein"23820845
D008694MethamphetamineBBC3 protein affects the reaction [Methamphetamine results in decreased cleavage of CASP3 protein]26524635
D008694MethamphetamineBBC3 protein affects the reaction [Methamphetamine results in decreased cleavage of PARP1 protein]26524635
D008694MethamphetamineBBC3 protein affects the reaction [Methamphetamine results in decreased expression of BCL2 protein]26524635
D008694MethamphetamineBBC3 protein affects the reaction [Methamphetamine results in increased expression of BAX protein]26524635
D008694MethamphetamineMethamphetamine results in increased expression of BBC3 protein26524635
D008715Methionine[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of BBC3 gene20938992
D008727MethotrexateMethotrexate results in increased expression of BBC3 mRNA21114963|2167806
D008727MethotrexateMethotrexate affects the expression of BBC3 mRNA18502557
C553655methyl antcinate Amethyl antcinate A results in increased expression of BBC3 protein20557081
D008741Methyl MethanesulfonateMethyl Methanesulfonate results in increased expression of BBC3 mRNA23649840
D018817N-Methyl-3,4-methylenedioxyamphetamine"[N-Methyl-3,4-methylenedioxyamphetamine co-treated with Methamphetamine co-treated with 4-methylthioamphetamine co-treated with Dextroamphetamine] results in increased expression of BBC3 mRNA"23820845
D018817N-Methyl-3,4-methylenedioxyamphetamine"[N-Methyl-3,4-methylenedioxyamphetamine co-treated with Methamphetamine co-treated with 4-methylthioamphetamine co-treated with Dextroamphetamine] results in increased expression of BBC3 protein"23820845
D018817N-Methyl-3,4-methylenedioxyamphetamine"N-Methyl-3,4-methylenedioxyamphetamine results in increased expression of BBC3 mRNA"23820845
D018817N-Methyl-3,4-methylenedioxyamphetamine"N-Methyl-3,4-methylenedioxyamphetamine results in increased expression of BBC3 protein"23820845
D0156551-Methyl-4-phenylpyridinium1-Methyl-4-phenylpyridinium results in increased expression of BBC3 mRNA18266926
D0156551-Methyl-4-phenylpyridinium1-Methyl-4-phenylpyridinium results in increased expression of BBC3 mRNA23500530
D0156551-Methyl-4-phenylpyridiniumBBC3 protein affects the susceptibility to 1-Methyl-4-phenylpyridinium23500530
C008493methylselenic acidmethylselenic acid results in increased expression of BBC3 mRNA28161410
D008798Mevalonic AcidMevalonic Acid inhibits the reaction [Simvastatin results in increased expression of BBC3 protein]20045437
C066851mithramycin Amithramycin A inhibits the reaction [Fluorouracil results in increased expression of BBC3 protein]15489892
C066851mithramycin Amithramycin A inhibits the reaction [[TP53 protein binds to SP1 protein] which results in increased expression of BBC3 mRNA]15489892
C016599mono-(2-ethylhexyl)phthalatemono-(2-ethylhexyl)phthalate results in increased expression of BBC3 protein24706461
D008999MonocrotophosMonocrotophos results in increased expression of BBC3 mRNA20957986
D009020MorphineMorphine results in increased expression of BBC3 mRNA19397953
C437683motexafin gadolinium[Ascorbic Acid co-treated with Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of BBC3 protein20530418
C437683motexafin gadoliniumbenzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[Ascorbic Acid co-treated with Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of BBC3 protein]20530418
C523799MRK 003MRK 003 results in increased expression of BBC3 mRNA21169257
C583365N-(2-(1,1'-bicyclopropyl)-2-ylphenyl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide"N-(2-(1,1'-bicyclopropyl)-2-ylphenyl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide results in decreased expression of BBC3 mRNA"29244179
D037742Nanotubes, Carbon"Nanotubes, Carbon analog results in decreased expression of BBC3 mRNA"25554681|2562005
D037742Nanotubes, Carbon"Nanotubes, Carbon results in decreased expression of BBC3 mRNA"25554681|2562005
D009285NaphthoquinonesNaphthoquinones results in increased expression of BBC3 mRNA23811387
C051752nefazodonenefazodone results in increased expression of BBC3 mRNA27288927
C022838nickel chloridenickel chloride results in increased expression of BBC3 mRNA23566959|2855277
C022838nickel chlorideTP53 protein affects the reaction [nickel chloride results in increased expression of BBC3 mRNA]23566959
C022838nickel chloridenickel chloride affects the expression of BBC3 mRNA22546817
D009569Nitric OxideNitric Oxide results in increased expression of BBC3 mRNA15126337
D009585Nitrogen DioxideNitrogen Dioxide results in increased expression of BBC3 mRNA27206323
C014707nitrosobenzylmethylaminenitrosobenzylmethylamine results in increased expression of BBC3 mRNA17616710
C044387N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine"N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of BBC3 mRNA"12756304
C010615Nonidet P-40Nonidet P-40 results in increased expression of BBC3 mRNA26552463
C482205nutlin 3nutlin 3 promotes the reaction [Cisplatin results in increased expression of BBC3 mRNA]21109480
C482205nutlin 3nutlin 3 results in increased expression of BBC320422343
C482205nutlin 3nutlin 3 results in increased expression of BBC3 mRNA16439685
C482205nutlin 3nutlin 3 results in increased expression of BBC3 protein16014563|1643968
C482205nutlin 3TP53 protein affects the reaction [nutlin 3 results in increased expression of BBC3 protein]16439685
C025589ochratoxin Aochratoxin A results in decreased expression of BBC3 protein19367635
C025589ochratoxin A[NFE2L2 protein affects the susceptibility to ochratoxin A] which results in increased expression of BBC3 protein28710020
C025589ochratoxin Aochratoxin A promotes the reaction [NFE2L2 protein affects the expression of BBC3 mRNA]28710020
C025589ochratoxin Aochratoxin A results in increased expression of BBC3 mRNA28710020
C025589ochratoxin Asulforafan inhibits the reaction [ochratoxin A results in increased expression of BBC3 mRNA]28710020
C025589ochratoxin Aochratoxin A results in increased expression of BBC3 mRNA23208426
D019319Okadaic Acid"Okadaic Acid inhibits the reaction [2,4,5,2',4',5'-hexachlorobiphenyl inhibits the reaction [Benzo(a)pyrene results in increased expression of BBC3 protein]]"24954032
D019319Okadaic AcidOkadaic Acid inhibits the reaction [Estradiol inhibits the reaction [Benzo(a)pyrene results in increased expression of BBC3 protein]]24954032
D019319Okadaic AcidOkadaic Acid inhibits the reaction [Tetrachlorodibenzodioxin inhibits the reaction [Benzo(a)pyrene results in increased expression of BBC3 protein]]24954032
D019319Okadaic AcidBBC3 protein affects the susceptibility to Okadaic Acid20477944
D009966OrphenadrineOrphenadrine affects the expression of BBC3 mRNA23665939
C030110oxaliplatin[oxaliplatin co-treated with Topotecan] results in increased expression of BBC3 mRNA25729387
C030110oxaliplatinoxaliplatin results in increased expression of BBC3 mRNA25729387
D010100OxygenOxygen deficiency results in increased expression of BBC3 mRNA25596134
D010100Oxygen[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of BBC3 protein modified form28675767
D010100OxygenSIRT7 protein inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of BBC3 protein]28675767
D017239PaclitaxelBBC3 protein results in increased susceptibility to Paclitaxel16481741
D017239PaclitaxelPaclitaxel results in increased expression of BBC3 mRNA16481741
D017239PaclitaxelPaclitaxel results in increased expression of BBC3 protein16481741
D019308Palmitic Acid[Palmitic Acid co-treated with Glucose] results in increased expression of BBC3 mRNA24451382
D019308Palmitic AcidSIRT1 protein mutant form inhibits the reaction [[Palmitic Acid co-treated with Glucose] results in increased expression of BBC3 mRNA]24451382
D000073878Palm OilPalm Oil results in increased expression of BBC3 mRNA18042831
D010269ParaquatParaquat results in increased expression of BBC3 mRNA27288846
D010269ParaquatParaquat results in increased expression of BBC3 protein18266926
D052638Particulate MatterParticulate Matter results in increased expression of BBC3 mRNA24216475
D010396PenicillaminePenicillamine results in decreased expression of BBC3 protein22843330
C023036perfluorooctanoic acidperfluorooctanoic acid results in increased expression of BBC3 protein26879310
C011272perfosfamideperfosfamide results in increased expression of BBC3 mRNA17068108
C027579periodate-oxidized adenosineperiodate-oxidized adenosine affects the expression of BBC3 mRNA17097637
C539933pevonedistatpevonedistat affects the expression of BBC3 mRNA24634471
D010634PhenobarbitalPhenobarbital affects the expression of BBC3 mRNA19159669
C030090phosphoramide mustardphosphoramide mustard results in increased expression of BBC3 mRNA26708502|2788807
C522973PI103[Doxorubicin co-treated with PI103] results in increased expression of BBC3 protein20856197
C522973PI103TP53 protein promotes the reaction [[Doxorubicin co-treated with PI103] results in increased expression of BBC3 protein]20856197
C121565pifithrinpifithrin inhibits the reaction [Simvastatin results in increased expression of BBC3 mRNA]20045437
C121565pifithrinpifithrin inhibits the reaction [Simvastatin results in increased expression of BBC3 protein]20045437
C121565pifithrin"pifithrin inhibits the reaction [6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [resveratrol inhibits the reaction [Cisplatin results in increased expression of BBC3 protein]]]"21593185
C121565pifithrinpifithrin inhibits the reaction [APP protein alternative form results in increased expression of BBC3 protein]24567336
C121565pifithrinpifithrin inhibits the reaction [Doxorubicin results in increased expression of BBC3 protein]18775851
C121565pifithrinpifithrin results in decreased expression of BBC3 mRNA19475672
C121565pifithrinpifithrin results in decreased expression of BBC3 protein18364113|1909596
D010936Plant ExtractsPlant Extracts results in decreased expression of BBC3 mRNA23557933
C060540polyhexamethyleneguanidinepolyhexamethyleneguanidine results in increased expression of BBC3 mRNA24583197
C060540polyhexamethyleneguanidinepolyhexamethyleneguanidine results in increased expression of BBC3 protein24583197
C472086polyphenon Epolyphenon E results in increased expression of BBC3 protein23285096
D011192Potassium DichromatePotassium Dichromate results in increased expression of BBC3 protein26348139
D011441PropylthiouracilPropylthiouracil results in increased expression of BBC3 mRNA24780913
C010423pyrithione zincpyrithione zinc results in increased expression of BBC3 protein20151177
C059514resveratrolErlotinib Hydrochloride promotes the reaction [resveratrol results in increased expression of BBC3 protein]25895606
C059514resveratrolresveratrol promotes the reaction [Erlotinib Hydrochloride results in increased expression of BBC3 protein]25895606
C059514resveratrolresveratrol results in increased expression of BBC3 mRNA26341291
C059514resveratrolresveratrol results in increased expression of BBC3 protein17636462|2553394
C059514resveratrol"6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [resveratrol inhibits the reaction [Cisplatin results in increased expression of BBC3 protein]]"21593185
C059514resveratrol"pifithrin inhibits the reaction [6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [resveratrol inhibits the reaction [Cisplatin results in increased expression of BBC3 protein]]]"21593185
C059514resveratrolresveratrol inhibits the reaction [Cisplatin results in increased expression of BBC3 protein]21593185
D012431Rutin"Rutin inhibits the reaction [Cholesterol, Dietary results in increased expression of BBC3 mRNA]"27239252
C005705sanguinarine[sanguinarine co-treated with arsenic trioxide] results in increased expression of BBC3 mRNA24345465
C417521SB 216763SB 216763 inhibits the reaction [Cisplatin results in increased expression of BBC3 protein]24560772
D012822Silicon DioxideSilicon Dioxide analog results in decreased expression of BBC3 mRNA25895662
D012822Silicon DioxideSilicon Dioxide analog results in increased expression of BBC3 mRNA23806026
D012822Silicon DioxideSilicon Dioxide results in increased expression of BBC3 mRNA19073995
D012822Silicon DioxideSilicon Dioxide results in increased expression of BBC3 protein26865670
D012822Silicon DioxideZC3H12A affects the reaction [Silicon Dioxide results in increased expression of BBC3 protein]26865670
D019821SimvastatinMevalonic Acid inhibits the reaction [Simvastatin results in increased expression of BBC3 protein]20045437
D019821Simvastatinpifithrin inhibits the reaction [Simvastatin results in increased expression of BBC3 mRNA]20045437
D019821Simvastatinpifithrin inhibits the reaction [Simvastatin results in increased expression of BBC3 protein]20045437
D019821SimvastatinSimvastatin affects the localization of BBC3 protein20045437
D019821SimvastatinSimvastatin results in increased expression of BBC3 mRNA17428261|2004543
D019821SimvastatinSimvastatin results in increased expression of BBC3 protein20045437
D020123Sirolimus[[Sirolimus co-treated with Cisplatin] results in increased expression of TP73 protein] which results in increased expression of BBC3 protein20686837
D020123SirolimusSirolimus promotes the reaction [TP53 protein results in increased expression of BBC3 protein]19560264
C017947sodium arseniteBBC3 results in increased susceptibility to sodium arsenite16166651
C017947sodium arsenitesodium arsenite results in increased expression of and affects the localization of BBC3 protein16166651
C017947sodium arsenitesodium arsenite results in increased expression of and results in increased activity of BBC3 protein20477944
C017947sodium arsenitesodium arsenite results in increased expression of BBC3 mRNA16166651|2047794
C017947sodium arseniteTRP53 gene mutant form affects the reaction [sodium arsenite results in increased expression of BBC3 mRNA]16166651
C017947sodium arseniteTRP53 gene mutant form affects the reaction [sodium arsenite results in increased expression of BBC3 protein]16166651
C017947sodium arseniteTRP73 protein affects the reaction [sodium arsenite results in increased activity of BBC3 protein]20477944
C017947sodium arseniteTRP73 protein affects the reaction [sodium arsenite results in increased expression of BBC3 mRNA]20477944
D018038Sodium SeleniteSodium Selenite results in increased expression of BBC3 mRNA28161410
D053260SootSoot results in decreased expression of BBC3 mRNA22461453
C016766sulforafansulforafan inhibits the reaction [ochratoxin A results in increased expression of BBC3 mRNA]28710020
D013467SulindacSulindac results in increased expression of BBC3 mRNA11906190
D013605T-2 ToxinT-2 Toxin results in increased expression of BBC3 mRNA26141394
D013629TamoxifenTamoxifen affects the expression of BBC3 mRNA20937368
D013629TamoxifenTamoxifen results in decreased expression of BBC3 mRNA25123088
C508490TDP 521252TDP 521252 results in increased expression of BBC3 mRNA16432175
C508490TDP 521252TDP 521252 results in increased expression of BBC3 protein16432175
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of BBC3 mRNA16714409
D013749Tetrachlorodibenzodioxinfostriecin inhibits the reaction [Tetrachlorodibenzodioxin inhibits the reaction [Benzo(a)pyrene results in increased expression of BBC3 protein]]24954032
D013749TetrachlorodibenzodioxinOkadaic Acid inhibits the reaction [Tetrachlorodibenzodioxin inhibits the reaction [Benzo(a)pyrene results in increased expression of BBC3 protein]]24954032
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin inhibits the reaction [Benzo(a)pyrene results in increased expression of BBC3 protein]24954032
D013749Tetrachlorodibenzodioxin"Tetrachlorodibenzodioxin inhibits the reaction [dibenzo(a,l)pyrene affects the expression of BBC3 protein]"24954032
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of BBC3 mRNA21570461
D013749Tetrachlorodibenzodioxin[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of BBC3 mRNA17942748
D019284ThapsigarginThapsigargin results in increased expression of BBC3 mRNA22378314
D019284ThapsigarginThapsigargin results in increased expression of BBC3 mRNA16018998
D008063Thioctic AcidThioctic Acid inhibits the reaction [arsenic trioxide results in increased expression of BBC3 mRNA]23892647
D014028Tobacco Smoke PollutionTobacco Smoke Pollution results in decreased expression of BBC3 mRNA27255386
D019772Topotecan[oxaliplatin co-treated with Topotecan] results in increased expression of BBC3 mRNA25729387
D019772TopotecanTopotecan results in increased expression of BBC3 mRNA25729387
D014212TretinoinTretinoin inhibits the reaction [Cisplatin results in increased expression of BBC3 mRNA]21532991
C012589trichostatin Atrichostatin A results in increased expression of BBC3 mRNA15901671
C012589trichostatin AEtoposide promotes the reaction [trichostatin A results in increased expression of BBC3 protein]25699604
C012589trichostatin Atrichostatin A promotes the reaction [Etoposide results in increased expression of BBC3 protein]25699604
C012589trichostatin Atrichostatin A results in increased expression of BBC3 mRNA21527555
C012589trichostatin Atrichostatin A results in increased expression of BBC3 protein25699604
C040533trimethyltin chloridetrimethyltin chloride results in increased expression of BBC3 mRNA23000284
C040533trimethyltin chloridetrimethyltin chloride promotes the reaction [TP53 protein results in increased expression of BBC3 mRNA]19655806
C016805tris(1,3-dichloro-2-propyl)phosphate"tris(1,3-dichloro-2-propyl)phosphate results in increased expression of BBC3 mRNA"26179874
C002802tungsten carbide[tungsten carbide co-treated with Cobalt] results in increased expression of BBC3 mRNA18078969
D014415TunicamycinTunicamycin results in increased expression of BBC3 mRNA22378314
C113580U 0126U 0126 inhibits the reaction [Doxorubicin results in increased expression of BBC3 protein]18775851
C000602704UF010 compoundEtoposide promotes the reaction [UF010 compound results in increased expression of BBC3 protein]25699604
C000602704UF010 compoundUF010 compound promotes the reaction [Etoposide results in increased expression of BBC3 protein]25699604
C000602704UF010 compoundUF010 compound results in increased expression of BBC3 protein25699604
D014520UrethaneUrethane results in increased expression of BBC3 mRNA28818685
C406224valdecoxibvaldecoxib results in increased expression of BBC3 mRNA24136188
D014635Valproic AcidValproic Acid results in increased expression of BBC3 mRNA15901671
D014635Valproic AcidValproic Acid affects the expression of BBC3 mRNA17292431|1796380
D001335Vehicle EmissionsVehicle Emissions results in increased expression of BBC3 mRNA24216475
C551177vemurafenib[BRAF protein mutant form results in increased susceptibility to vemurafenib] which results in increased expression of BBC3 protein27689874
C551177vemurafenib[MET protein affects the susceptibility to HGF protein] affects the reaction [[BRAF protein mutant form results in increased susceptibility to vemurafenib] which results in increased expression of BBC3 protein]27689874
C029297vinylidene chloridevinylidene chloride results in increased expression of BBC3 mRNA26682919
D009536Niacinamide[Berberine co-treated with Niacinamide] results in increased expression of BBC3 mRNA26712469
D009536NiacinamideNiacinamide results in increased expression of BBC3 mRNA26712469
D024483Vitamin K 3Vitamin K 3 affects the expression of BBC3 mRNA20044591
C111237vorinostatTNFSF10 protein promotes the reaction [vorinostat results in increased expression of BBC3 mRNA]19509267
C111237vorinostatTNFSF10 protein promotes the reaction [vorinostat results in increased expression of BBC3 protein]19509267
C111237vorinostatvorinostat results in increased expression of BBC3 mRNA19509267|2152755
C111237vorinostatvorinostat results in increased expression of BBC3 protein19509267
D019345Zinc Acetate[Ascorbic Acid co-treated with Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of BBC3 protein20530418
D019345Zinc Acetatebenzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[Ascorbic Acid co-treated with Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of BBC3 protein]20530418
C016837zinc chloridezinc chloride promotes the reaction [Doxorubicin results in increased expression of BBC3 mRNA]19714248
D019287Zinc SulfateZinc Sulfate results in increased expression of BBC3 mRNA12756304

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0005515protein binding-IPI26212789  
GO:0051117ATPase binding-IPI26212789  
GO ID GO Term Qualifier Evidence PubMed
GO:0001836release of cytochrome c from mitochondria-IBA21873635  
GO:0006915apoptotic process-IMP26212789  
GO:0006919activation of cysteine-type endopeptidase activity involved in apoptotic process-IBA21873635  
GO:0043065positive regulation of apoptotic process-IBA21873635  
GO:0043280positive regulation of cysteine-type endopeptidase activity involved in apoptotic process-IBA21873635  
GO:0070059intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress-IBA21873635  
GO:0090200positive regulation of release of cytochrome c from mitochondria-IBA21873635  
GO:0097194execution phase of apoptosis-IBA21873635  
GO:1900740positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway-IBA21873635  
GO:2001056positive regulation of cysteine-type endopeptidase activity-IBA21873635  
GO ID GO Term Qualifier Evidence PubMed
GO:0005739mitochondrion-IBA21873635  
GO:0005739mitochondrion-TAS26212789  
GO:0005764lysosomecolocalizes_withIDA26212789  
KEGG ID KEGG Term
hsa04115p53 signaling pathway
hsa05016Huntington's disease
Reactome ID Reactome Term Evidence
R-HSA-109581ApoptosisTAS
R-HSA-109606Intrinsic Pathway for ApoptosisTAS
R-HSA-111453BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 membersTAS
R-HSA-114452Activation of BH3-only proteinsTAS
R-HSA-139915Activation of PUMA and translocation to mitochondriaTAS
R-HSA-212436Generic Transcription PathwayTAS
R-HSA-3700989Transcriptional Regulation by TP53TAS
R-HSA-5357801Programmed Cell DeathTAS
R-HSA-5633008TP53 Regulates Transcription of Cell Death GenesTAS
R-HSA-6803204TP53 Regulates Transcription of Genes Involved in Cytochrome C ReleaseTAS
R-HSA-73857RNA Polymerase II TranscriptionTAS
R-HSA-74160Gene expression (Transcription)TAS

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
23144912DNA repair and cell cycle biomarkers of radiation exposure and inflammation stress in human blood. (2012)Budworth HPLoS One