Gene: GPC3

2719
DGSX|GTR2-2|MXR7|OCI-5|SDYS|SGB|SGBS|SGBS1
glypican 3
protein-coding
Xq26.2
Ensembl:ENSG00000147257 MIM:300037 Vega:OTTHUMG00000022448 UniprotKB:P51654
NG_009286.1
PubMed
0   ANCO-SNPs
ND
1   
NA (AD)  NA (ND)   (Frontal_Cortex)
NA (AD)  NA (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
OGN0.792
TSPAN20.745
ESM10.716
PLN0.713
COL14A10.71
TRABD2B0.706
ITIH20.706
MYOCD0.705
COL8A10.699
LUM0.694

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
FEZF2-0.354
PLIN5-0.325
CABLES1-0.322
PLIN4-0.321
GRIN2C-0.31
IGFALS-0.309
CNTFR-0.309
SORCS2-0.306
PNPLA7-0.297
RHCG-0.291

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C4049102,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane"2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of GPC3 mRNA]"19414516
C4049102,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane"2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [FSHB protein affects the expression of GPC3 mRNA]"19414516
C0495842-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine"2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of GPC3 mRNA"15215175
C0065512-amino-2-methyl-1-propanol2-amino-2-methyl-1-propanol results in decreased expression of GPC3 mRNA25088246
C0230353,4,5,3',4'-pentachlorobiphenyl"3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of GPC3 mRNA"23196670
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with entinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of GPC3 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with panobinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of GPC3 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of GPC3 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of GPC3 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of GPC3 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with vorinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of GPC3 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with entinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of GPC3 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with panobinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of GPC3 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of GPC3 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of GPC3 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of GPC3 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with vorinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of GPC3 mRNA"27188386
D000082AcetaminophenAcetaminophen affects the expression of GPC3 mRNA17562736
D020106AcrylamideAcrylamide results in decreased expression of GPC3 mRNA28959563
D000242Cyclic AMP"2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of GPC3 mRNA]"19414516
D016604Aflatoxin B1Aflatoxin B1 results in decreased expression of GPC3 mRNA27153756
D016604Aflatoxin B1Aflatoxin B1 results in decreased methylation of GPC3 gene27153756
D016604Aflatoxin B1Aflatoxin B1 results in increased expression of GPC3 mRNA23630614
D018501Antirheumatic AgentsAntirheumatic Agents results in increased expression of GPC3 mRNA24449571
D001104ArbutinArbutin results in decreased expression of GPC3 mRNA17103032
D001205Ascorbic Acid[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in increased expression of GPC3 mRNA28189605
D001205Ascorbic Acidcadmium sulfate inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in increased expression of GPC3 mRNA]28189605
D001280AtrazineAtrazine results in increased expression of GPC3 mRNA22378314
C547126AZM551248AZM551248 results in decreased expression of GPC3 mRNA22323515
D019324beta-Naphthoflavone[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of GPC3 mRNA18164116
D004958Estradiol[bisphenol A co-treated with Estradiol] results in decreased expression of GPC3 mRNA26496021
C031463beta-glycerophosphoric acid[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in increased expression of GPC3 mRNA28189605
C031463beta-glycerophosphoric acidcadmium sulfate inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in increased expression of GPC3 mRNA]28189605
C006780bisphenol A[bisphenol A co-treated with Estradiol] results in decreased expression of GPC3 mRNA26496021
C006780bisphenol A[bisphenol A co-treated with Testosterone] results in decreased expression of GPC3 mRNA26496021
C006780bisphenol Abisphenol A results in decreased expression of GPC3 mRNA25181051
C037123cadmium sulfatecadmium sulfate inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in increased expression of GPC3 mRNA]28189605
D002110CaffeineCaffeine affects the expression of GPC3 mRNA20864626
D002220CarbamazepineCarbamazepine affects the expression of GPC3 mRNA25979313
D002251Carbon TetrachlorideAFR2 protein affects the reaction [Carbon Tetrachloride results in increased expression of GPC3 mRNA]17668883
D002251Carbon TetrachlorideCarbon Tetrachloride results in increased expression of GPC3 mRNA17668883
D004390ChlorpyrifosChlorpyrifos results in increased expression of GPC3 mRNA20691718
D003471CuprizoneCuprizone results in increased expression of GPC3 mRNA26577399
D016572CyclosporineCyclosporine results in decreased expression of GPC3 mRNA25562108|2798913
D003907DexamethasoneDexamethasone results in increased expression of GPC3 mRNA25047013
D003907Dexamethasone[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in increased expression of GPC3 mRNA28189605
D003907Dexamethasonecadmium sulfate inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in increased expression of GPC3 mRNA]28189605
D002945CisplatinGPC3 mRNA results in increased susceptibility to Cisplatin25199881
C036042dicyclohexyl phthalatedicyclohexyl phthalate affects the expression of GPC3 mRNA26924002
D004052Diethylnitrosamine[Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of GPC3 mRNA24535843
D004052DiethylnitrosamineDiethylnitrosamine results in increased expression of GPC3 mRNA24535843
D004052Diethylnitrosamine[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of GPC3 mRNA18164116
D0151279,10-Dimethyl-1,2-benzanthracene"9,10-Dimethyl-1,2-benzanthracene results in decreased expression of GPC3 mRNA"22485181
D004237DiuronDiuron results in decreased expression of GPC3 mRNA21551480|2515243
D004317DoxorubicinGPC3 mRNA results in increased susceptibility to Doxorubicin25199881
C118739entinostatentinostat results in decreased expression of GPC3 mRNA26272509
C118739entinostatentinostat results in increased expression of GPC3 mRNA27188386
C118739entinostat"[NOG protein co-treated with entinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of GPC3 mRNA"27188386
D004997Ethinyl EstradiolEthinyl Estradiol results in decreased expression of GPC3 mRNA17942748
D004997Ethinyl EstradiolEthinyl Estradiol results in decreased expression of GPC3 mRNA15576828|1583489
D0150732-Acetylaminofluorene2-Acetylaminofluorene results in increased expression of GPC3 mRNA17187413
C039281furanfuran results in increased expression of GPC3 mRNA27387713
C056507gemcitabinegemcitabine results in increased expression of GPC3 mRNA17039268
C016517indole-3-carbinolindole-3-carbinol affects the expression of GPC3 mRNA21396975
C410337K 7174K 7174 results in decreased expression of GPC3 mRNA24086573
D008727MethotrexateGPC3 mRNA results in increased susceptibility to Methotrexate25199881
C004925methylmercuric chloridemethylmercuric chloride results in decreased expression of GPC3 mRNA28001369
D008741Methyl MethanesulfonateMethyl Methanesulfonate results in decreased expression of GPC3 mRNA26011545
C406082monomethylarsonous acidmonomethylarsonous acid affects the expression of GPC3 mRNA25177542
C406082monomethylarsonous acidmonomethylarsonous acid results in increased expression of GPC3 mRNA22108045
C517284monomethyl phthalatemonomethyl phthalate affects the expression of GPC3 mRNA26924002
C500085muraglitazarmuraglitazar results in increased expression of GPC3 mRNA21515302
D037742Nanotubes, Carbon"Nanotubes, Carbon analog results in decreased expression of GPC3 mRNA"25554681
D037742Nanotubes, Carbon"Nanotubes, Carbon results in decreased expression of GPC3 mRNA"25554681
D009532NickelNickel results in decreased expression of GPC3 mRNA24768652|2558310
D017239PaclitaxelGPC3 mRNA results in increased susceptibility to Paclitaxel25199881
C496932panobinostat"[NOG protein co-treated with panobinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of GPC3 mRNA"27188386
C496932panobinostatpanobinostat results in decreased expression of GPC3 mRNA26272509
C023036perfluorooctanoic acidperfluorooctanoic acid results in decreased expression of GPC3 protein26879310
D010634Phenobarbital[Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of GPC3 mRNA24535843
D010662Phenylmercuric Acetate"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of GPC3 mRNA"27188386
D010662Phenylmercuric AcetatePhenylmercuric Acetate results in decreased expression of GPC3 mRNA26272509
C006253pirinixic acidpirinixic acid results in increased expression of GPC3 mRNA23811191
C006253pirinixic acidpirinixic acid results in decreased expression of GPC3 mRNA19162173
D011441PropylthiouracilPropylthiouracil results in increased expression of GPC3 mRNA24780913
D020849Raloxifene HydrochlorideRaloxifene Hydrochloride results in increased expression of GPC3 mRNA15576828
C089730rosiglitazonerosiglitazone results in increased expression of GPC3 mRNA21515302
D012601Scopolamine HydrobromideScopolamine Hydrobromide results in decreased expression of GPC3 mRNA12818353
D053260SootSoot results in decreased expression of GPC3 mRNA26551751
C501413tesaglitazartesaglitazar results in increased expression of GPC3 mRNA21515302
D013739Testosterone[bisphenol A co-treated with Testosterone] results in decreased expression of GPC3 mRNA26496021
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of GPC3 mRNA21570461
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin promotes the reaction [AHR protein binds to GPC3 promoter]19654925
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of GPC3 mRNA21215274
C009495titanium dioxidetitanium dioxide results in decreased expression of GPC3 mRNA23557971
D014028Tobacco Smoke PollutionTobacco Smoke Pollution affects the expression of GPC3 mRNA20133372
C066340tolcaponetolcapone binds to GPC3 protein19783845
D019772TopotecanGPC3 mRNA results in increased susceptibility to Topotecan25199881
D014212TretinoinTretinoin results in decreased expression of GPC3 mRNA23724009
C012589trichostatin A"[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of GPC3 mRNA"27188386
C012589trichostatin Atrichostatin A results in decreased expression of GPC3 mRNA24935251|2627250
C015559trimellitic anhydridetrimellitic anhydride results in decreased expression of GPC3 mRNA19042947
D014635Valproic Acid"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of GPC3 mRNA"27188386
D014635Valproic AcidValproic Acid affects the expression of GPC3 mRNA25979313
D014635Valproic AcidValproic Acid results in decreased expression of GPC3 mRNA23179753|2438349
D014635Valproic AcidValproic Acid results in increased expression of GPC3 mRNA23179753|2718838
D014635Valproic AcidValproic Acid results in increased methylation of GPC3 gene29154799
D014635Valproic AcidValproic Acid results in increased expression of GPC3 mRNA24896083
D014640VancomycinVancomycin results in decreased expression of GPC3 mRNA18930951
D001335Vehicle EmissionsVehicle Emissions results in decreased methylation of GPC3 gene25560391
C025643vinclozolinvinclozolin affects the expression of GPC3 mRNA19015723
D014750VincristineGPC3 mRNA results in increased susceptibility to Vincristine25199881
C111237vorinostat"[NOG protein co-treated with vorinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of GPC3 mRNA"27188386
C111237vorinostatvorinostat results in decreased expression of GPC3 mRNA26272509
C088658zoledronic acidzoledronic acid results in decreased expression of GPC3 mRNA24714768

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0005515protein binding-IPI17549790  29162697  
GO:0060422peptidyl-dipeptidase inhibitor activity-IDA17549790  
GO ID GO Term Qualifier Evidence PubMed
GO:0001523retinoid metabolic process-TAS-  
GO:0001658branching involved in ureteric bud morphogenesis-IEA-  
GO:0006024glycosaminoglycan biosynthetic process-TAS-  
GO:0006027glycosaminoglycan catabolic process-TAS-  
GO:0009653anatomical structure morphogenesis-TAS8589713  
GO:0009948anterior/posterior axis specification-IEA-  
GO:0010171body morphogenesis-IEA-  
GO:0010466negative regulation of peptidase activity-IEA-  
GO:0030282bone mineralization-IEA-  
GO:0030316osteoclast differentiation-IEA-  
GO:0030324lung development-IEA-  
GO:0030513positive regulation of BMP signaling pathway-IEA-  
GO:0035116embryonic hindlimb morphogenesis-IEA-  
GO:0043687post-translational protein modification-TAS-  
GO:0044267cellular protein metabolic process-TAS-  
GO:0045732positive regulation of protein catabolic process-IEA-  
GO:0045807positive regulation of endocytosis-IEA-  
GO:0045879negative regulation of smoothened signaling pathway-IEA-  
GO:0045880positive regulation of smoothened signaling pathway-IEA-  
GO:0045926negative regulation of growth-IEA-  
GO:0046326positive regulation of glucose import-IEA-  
GO:0050680negative regulation of epithelial cell proliferation-IEA-  
GO:0060976coronary vasculature development-IEA-  
GO:0072138mesenchymal cell proliferation involved in ureteric bud development-ISS-  
GO:0072180mesonephric duct morphogenesis-IEA-  
GO:0072203cell proliferation involved in metanephros development-IEA-  
GO:0090090negative regulation of canonical Wnt signaling pathway-IEA-  
GO:2000096positive regulation of Wnt signaling pathway, planar cell polarity pathway-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO:0005615extracellular space-IEA-  
GO:0005788endoplasmic reticulum lumen-TAS-  
GO:0005796Golgi lumen-TAS-  
GO:0005886plasma membrane-TAS-  
GO:0031226intrinsic component of plasma membrane-TAS7657705  
GO:0043202lysosomal lumen-TAS-  
GO:0046658anchored component of plasma membrane-IEA-  
GO:0062023collagen-containing extracellular matrix-IEA-  
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence
R-HSA-1430728MetabolismTAS
R-HSA-1430728MetabolismIEA
R-HSA-162582Signal TransductionTAS
R-HSA-1630316Glycosaminoglycan metabolismTAS
R-HSA-1630316Glycosaminoglycan metabolismIEA
R-HSA-1638091Heparan sulfate/heparin (HS-GAG) metabolismTAS
R-HSA-1638091Heparan sulfate/heparin (HS-GAG) metabolismIEA
R-HSA-1643685DiseaseTAS
R-HSA-1793185Chondroitin sulfate/dermatan sulfate metabolismTAS
R-HSA-196854Metabolism of vitamins and cofactorsTAS
R-HSA-1971475A tetrasaccharide linker sequence is required for GAG synthesisTAS
R-HSA-2022928HS-GAG biosynthesisTAS
R-HSA-2022928HS-GAG biosynthesisIEA
R-HSA-2024096HS-GAG degradationTAS
R-HSA-2187338Visual phototransductionTAS
R-HSA-3560782Diseases associated with glycosaminoglycan metabolismTAS
R-HSA-3560783Defective B4GALT7 causes EDS, progeroid typeTAS
R-HSA-3560801Defective B3GAT3 causes JDSSDHDTAS
R-HSA-3656237Defective EXT2 causes exostoses 2TAS
R-HSA-3656253Defective EXT1 causes exostoses 1, TRPS2 and CHDSTAS
R-HSA-372790Signaling by GPCRTAS
R-HSA-3781865Diseases of glycosylationTAS
R-HSA-381426Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)TAS
R-HSA-388396GPCR downstream signallingTAS
R-HSA-392499Metabolism of proteinsTAS
R-HSA-418594G alpha (i) signalling eventsTAS
R-HSA-4420332Defective B3GALT6 causes EDSP2 and SEMDJL1TAS
R-HSA-597592Post-translational protein modificationTAS
R-HSA-6806667Metabolism of fat-soluble vitaminsTAS
R-HSA-71387Metabolism of carbohydratesTAS
R-HSA-71387Metabolism of carbohydratesIEA
R-HSA-8957275Post-translational protein phosphorylationTAS
R-HSA-975634Retinoid metabolism and transportTAS

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
12816733The heparan sulfate proteoglycan GPC3 is a potential lung tumor suppressor. (2003 Dec)Kim HAm J Respir Cell Mol Biol