Gene: SULT1C4

27233
SULT1C|SULT1C2
sulfotransferase family 1C member 4
protein-coding
2q12.3
Ensembl:ENSG00000198075 MIM:608357 Vega:OTTHUMG00000130958 UniprotKB:O75897
NC_000002.12
PubMed
0   ANCO-SNPs
OD
1   
NA (AD)  NA (ND)   (Frontal_Cortex)
7.542e-1 (AD)  1.144e-1 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
YAP10.853
PLSCR40.852
LEPROT0.851
MAML20.85
CD3020.849
CYBRD10.843
FERMT20.84
LIX10.834
TSPAN60.834
CDC14A0.833

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
GALNT14-0.56
ABCC12-0.547
ADTRP-0.537
CACNA1F-0.537
PIP5KL1-0.524
AGMAT-0.523
BCL11A-0.52
CALHM1-0.517
KCNB2-0.512
RHO-0.508

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SULT1C4 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SULT1C4 mRNA"27188386
D000082AcetaminophenAcetaminophen results in increased expression of SULT1C4 mRNA22230336
D016604Aflatoxin B1Aflatoxin B1 affects the expression of SULT1C4 protein20106945
D016604Aflatoxin B1Aflatoxin B1 results in increased expression of SULT1C4 mRNA21632981|2715375
C006632arsenic trioxidearsenic trioxide results in increased expression of SULT1C4 mRNA26705709
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of SULT1C4 mRNA21632981|2187194
C036042dicyclohexyl phthalatedicyclohexyl phthalate affects the expression of SULT1C4 mRNA26924002
C004925methylmercuric chloridemethylmercuric chloride results in increased expression of SULT1C4 mRNA28001369
C517284monomethyl phthalatemonomethyl phthalate affects the expression of SULT1C4 mRNA26924002
D010662Phenylmercuric Acetate"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SULT1C4 mRNA"27188386
D010662Phenylmercuric AcetatePhenylmercuric Acetate results in increased expression of SULT1C4 mRNA26272509
C005556propionaldehydepropionaldehyde results in decreased expression of SULT1C4 mRNA26079696
C012589trichostatin Atrichostatin A results in increased expression of SULT1C4 mRNA24935251
D014635Valproic AcidValproic Acid results in decreased expression of SULT1C4 mRNA29154799
D014635Valproic AcidValproic Acid results in increased expression of SULT1C4 mRNA24383497|2493525

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0004062aryl sulfotransferase activity-IDA23207770  
GO:0004062aryl sulfotransferase activity-TAS-  
GO:0008146sulfotransferase activity-IDA20056724  
GO:0008146sulfotransferase activity-NAS9852044  
GO:0008146sulfotransferase activity-TAS-  
GO ID GO Term Qualifier Evidence PubMed
GO:0006068ethanol catabolic process-IDA23207770  
GO:00504273'-phosphoadenosine 5'-phosphosulfate metabolic process-IDA23207770  
GO:00504273'-phosphoadenosine 5'-phosphosulfate metabolic process-TAS-  
GO:0051923sulfation-IDA20056724  23207770  
GO ID GO Term Qualifier Evidence PubMed
GO:0005575cellular_component-ND-  
GO:0005829cytosol-IDA-  
GO:0005829cytosol-TAS-  
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence
R-HSA-1430728MetabolismTAS
R-HSA-156580Phase II - Conjugation of compoundsTAS
R-HSA-156584Cytosolic sulfonation of small moleculesTAS
R-HSA-211859Biological oxidationsTAS

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
22946908Sulfation of buprenorphine, pentazocine, and naloxone by human cytosolic sulfotransferases. (2012 Jun 1)Kurogi KDrug Metab Lett