Gene: GNAI2

2771
GIP|GNAI2B|H_LUCA15.1|H_LUCA16.1
G protein subunit alpha i2
protein-coding
3p21.31
Ensembl:ENSG00000114353 MIM:139360 Vega:OTTHUMG00000156940 UniprotKB:P04899
NG_016002.2
PubMed
0   ANCO-SNPs
ND
1   
NA (AD)  NA (ND)   (Frontal_Cortex)
6.199e-1 (AD)  7.206e-1 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
RHOA0.911
CD630.909
HNRNPUL10.897
PFN10.893
PKN10.89
GSTP10.889
CORO1B0.889
CTNNA10.888
RPL100.886
RPL80.882

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
OR4F29-0.798
OR4F5-0.788
TYRP1-0.163
CDH7-0.163
ASB18-0.159
GABRG3-0.158
OR2M4-0.156
ATP12A-0.155
IL1RAPL2-0.154
OPRD1-0.151

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C0495842-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine"2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of GNAI2 mRNA"15215175
C0095054,4'-diaminodiphenylmethane"4,4'-diaminodiphenylmethane results in increased expression of GNAI2 mRNA"25380136
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide results in increased expression of GNAI2 protein"25670856
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of GNAI2 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of GNAI2 mRNA"27188386
D000082AcetaminophenAcetaminophen results in increased expression of GNAI2 mRNA22230336
D000111AcetylcysteineAcetylcysteine affects the reaction [IER3 protein affects the expression of GNAI2 mRNA]20713914
D000111AcetylcysteineAcetylcysteine inhibits the reaction [Glucose results in decreased expression of GNAI2 protein]18441196
D000111AcetylcysteineAcetylcysteine inhibits the reaction [Streptozocin results in decreased expression of GNAI2 protein]18441196
D000242Cyclic AMP[[IER3 protein affects the chemical synthesis of Reactive Oxygen Species] which results in increased expression of GNAI2] which results in decreased chemical synthesis of Cyclic AMP20713914
D016604Aflatoxin B1Aflatoxin B1 results in increased methylation of GNAI2 gene27153756
D024502alpha-Tocopherolalpha-Tocopherol inhibits the reaction [Glucose results in decreased expression of GNAI2 protein]18441196
D000535AluminumAluminum results in decreased expression of GNAI2 protein9626627
D000596Amino AcidsGNAI2 gene mutant form inhibits the reaction [[Glucose co-treated with Amino Acids] results in increased secretion of INS1 protein]25205820
D001280AtrazineAtrazine results in increased expression of GNAI2 mRNA22378314
C006780bisphenol Abisphenol A affects the expression of GNAI2 mRNA21786754
C006780bisphenol Abisphenol A affects the expression of GNAI2 mRNA21786754
C006780bisphenol Abisphenol A results in increased expression of GNAI2 mRNA25181051
D0151248-Bromo Cyclic Adenosine Monophosphate8-Bromo Cyclic Adenosine Monophosphate inhibits the reaction [S-Nitroso-N-Acetylpenicillamine results in decreased expression of GNAI2 protein]19252090
D001971BromocriptineGNAI2 protein mutant form inhibits the reaction [Bromocriptine results in increased activity of ABCB1B promoter]9111066
C584509C646 compoundC646 compound results in decreased expression of GNAI2 mRNA26191083
D002110CaffeineCaffeine results in decreased expression of GNAI2 protein15708489
D002118CalciumCalcium affects the expression of GNAI2 mRNA15913539
D002251Carbon TetrachlorideCarbon Tetrachloride results in increased expression of GNAI2 mRNA27339419
D002273CarcinogensCarcinogens results in increased expression of GNAI2 mRNA16316942
D002713Chlorine[Ozone co-treated with Chlorine] results in decreased expression of GNAI2 mRNA18636392
C100187chloropicrinchloropicrin results in decreased expression of GNAI2 mRNA28476498
D004390ChlorpyrifosChlorpyrifos results in increased expression of GNAI2 mRNA17452286
D003024ClozapineClozapine results in decreased expression of GNAI2 mRNA15860345
C034456CMF regimenGNAI2 mRNA results in increased susceptibility to CMF regimen18925433
C018021cobaltous chloridecobaltous chloride results in decreased expression of GNAI2 mRNA19320972
D003300Copper[ATP7A gene mutant form results in increased abundance of Copper] which results in increased expression of GNAI2 mRNA15467011
D003300CopperCopper results in decreased expression of GNAI2 protein23882024
D003345CorticosteroneCorticosterone results in decreased expression of GNAI2 mRNA19477151
D003345CorticosteroneFluoxetine inhibits the reaction [Corticosterone results in decreased expression of GNAI2 mRNA]19477151
C030973cupric oxidecupric oxide analog results in decreased expression of GNAI2 protein23882024
D016572CyclosporineCyclosporine results in decreased expression of GNAI2 mRNA25562108
D003907Dexamethasone[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in decreased expression of GNAI2 mRNA16054899
D003907DexamethasoneDexamethasone results in increased expression of GNAI2 mRNA7730645
D003976DiazinonDiazinon affects the expression of GNAI2 mRNA17452286
D002945Cisplatin[Cisplatin co-treated with jinfukang] results in increased expression of GNAI2 mRNA27392435
D002945CisplatinCisplatin results in increased expression of GNAI2 mRNA27392435
D004128DimethylnitrosamineDimethylnitrosamine results in increased expression of GNAI2 mRNA25380136
D004155DiphenhydramineGNAI2 results in increased susceptibility to Diphenhydramine14614911
C007517diphenyleneiodoniumdiphenyleneiodonium affects the reaction [Glucose results in decreased expression of GNAI2 protein]18441196
C007517diphenyleneiodoniumdiphenyleneiodonium inhibits the reaction [Streptozocin results in decreased expression of GNAI2 protein]18441196
D004317DoxorubicinDoxorubicin results in decreased expression of GNAI2 mRNA19915844
D000431EthanolEthanol results in increased expression of GNAI2 mRNA20655511
D004997Ethinyl EstradiolEthinyl Estradiol results in increased expression of GNAI2 mRNA17108234
D015025ZearalenoneZearalenone results in increased expression of GNAI2 mRNA25455459
D005419FlavonoidsFlavonoids results in increased expression of GNAI2 mRNA18035473
D005473FluoxetineFluoxetine inhibits the reaction [Corticosterone results in decreased expression of GNAI2 mRNA]19477151
D005473FluoxetineFluoxetine results in decreased expression of GNAI2 mRNA21852994
C056933fumonisin B1fumonisin B1 results in increased expression of GNAI2 mRNA16221962
D005897GlafenineGlafenine results in increased expression of GNAI2 mRNA24136188
D005947GlucoseGNAI2 gene mutant form inhibits the reaction [[Glucose co-treated with Amino Acids] results in increased secretion of INS1 protein]25205820
D005947GlucoseGNAI2 gene mutant form inhibits the reaction [Glucose results in increased secretion of INS1 protein]25205820
D005947GlucoseAcetylcysteine inhibits the reaction [Glucose results in decreased expression of GNAI2 protein]18441196
D005947Glucosealpha-Tocopherol inhibits the reaction [Glucose results in decreased expression of GNAI2 protein]18441196
D005947Glucosediphenyleneiodonium affects the reaction [Glucose results in decreased expression of GNAI2 protein]18441196
D005947GlucoseGlucose results in decreased expression of GNAI2 protein18441196
D005947Glucosemanganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [Glucose results in decreased expression of GNAI2 protein]18441196
D005947GlucoseUric Acid inhibits the reaction [Glucose results in decreased expression of GNAI2 protein]18441196
C424943glutamyl-Se-methylselenocysteineglutamyl-Se-methylselenocysteine results in decreased expression of GNAI2 mRNA11306469
D006220HaloperidolHaloperidol results in decreased expression of GNAI2 mRNA15860345
C492448ICG 001ICG 001 results in decreased expression of GNAI2 mRNA26191083
D015759Ionomycin[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of GNAI2 mRNA25613284
D0150561-Methyl-3-isobutylxanthine[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in decreased expression of GNAI2 mRNA16054899
C544151jinfukang[Cisplatin co-treated with jinfukang] results in increased expression of GNAI2 mRNA27392435
C544151jinfukangjinfukang results in increased expression of GNAI2 mRNA27392435
D048628KetolidesKetolides analog results in increased expression of GNAI2 mRNA24967691
D008070LipopolysaccharidesLipopolysaccharides results in increased activity of GNAI2 protein21255617
D058185Magnetite Nanoparticles[Succimer co-treated with Magnetite Nanoparticles] results in decreased expression of GNAI2 mRNA26378955
C097284manganese(III)-tetrakis(4-benzoic acid)porphyrinmanganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [Glucose results in decreased expression of GNAI2 protein]18441196
C097284manganese(III)-tetrakis(4-benzoic acid)porphyrinmanganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [Peroxynitrous Acid results in decreased expression of GNAI2 protein]18055527
C097284manganese(III)-tetrakis(4-benzoic acid)porphyrinmanganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [S-Nitroso-N-Acetylpenicillamine results in decreased expression of GNAI2 protein]16962941
D008627Mercuric ChlorideMercuric Chloride affects the expression of GNAI2 mRNA20353558
D008727MethotrexateMethotrexate affects the expression of GNAI2 mRNA18502557
D018817N-Methyl-3,4-methylenedioxyamphetamine"N-Methyl-3,4-methylenedioxyamphetamine results in decreased expression of GNAI2 mRNA"20188158
D018817N-Methyl-3,4-methylenedioxyamphetamine"N-Methyl-3,4-methylenedioxyamphetamine results in increased expression of GNAI2 mRNA"20188158
D0156321-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine"1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of GNAI2 mRNA"20230807
D0156321-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine"[Nicotine co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in decreased expression of GNAI2 mRNA"20230807
D0156321-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine"Nicotine inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of GNAI2 mRNA]"20230807
C429014mitoquinonemitoquinone affects the reaction [IER3 protein affects the expression of GNAI2 mRNA]20713914
D009020MorphineMorphine promotes the reaction [GNAI2 protein binds to RGS17 protein]18652891
D009020MorphineMorphine results in decreased expression of GNAI2 mRNA15183518
D009020MorphineMorphine results in increased expression of GNAI2 mRNA15183518
D0150581-Naphthylisothiocyanate1-Naphthylisothiocyanate results in increased expression of GNAI2 mRNA25380136
C051752nefazodonenefazodone results in decreased expression of GNAI2 mRNA24136188
C028007nickel monoxidenickel monoxide results in decreased expression of GNAI2 mRNA19167457
D009538NicotineNicotine results in increased splicing of GNAI2 mRNA alternative form23825647
D009538Nicotine"[Nicotine co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in decreased expression of GNAI2 mRNA"20230807
D009538Nicotine"Nicotine inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of GNAI2 mRNA]"20230807
D009599NitroprussideNitroprusside results in decreased expression of GNAI2 protein16962941
D026423S-Nitroso-N-Acetylpenicillamine8-Bromo Cyclic Adenosine Monophosphate inhibits the reaction [S-Nitroso-N-Acetylpenicillamine results in decreased expression of GNAI2 protein]19252090
D026423S-Nitroso-N-Acetylpenicillaminemanganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [S-Nitroso-N-Acetylpenicillamine results in decreased expression of GNAI2 protein]16962941
D026423S-Nitroso-N-AcetylpenicillamineS-Nitroso-N-Acetylpenicillamine results in decreased expression of GNAI2 protein16962941|1925209
D026423S-Nitroso-N-AcetylpenicillamineUric Acid inhibits the reaction [S-Nitroso-N-Acetylpenicillamine results in decreased expression of GNAI2 protein]16962941
D010100OxygenOxygen deficiency results in decreased expression of GNAI2 protein10192281
D010126Ozone[Ozone co-treated with Chlorine] results in decreased expression of GNAI2 mRNA18636392
D052638Particulate MatterParticulate Matter results in increased expression of GNAI2 mRNA28412507
D010416PentachlorophenolPentachlorophenol results in increased expression of GNAI2 mRNA23892564
C023036perfluorooctanoic acidperfluorooctanoic acid results in decreased expression of GNAI2 protein26879310
D030421Peroxynitrous Acidmanganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [Peroxynitrous Acid results in decreased expression of GNAI2 protein]18055527
D030421Peroxynitrous AcidPeroxynitrous Acid results in decreased expression of GNAI2 protein18055527
D030421Peroxynitrous AcidUric Acid inhibits the reaction [Peroxynitrous Acid results in decreased expression of GNAI2 protein]18055527
D010634PhenobarbitalPhenobarbital affects the expression of GNAI2 mRNA23091169
D010852PicrotoxinPicrotoxin results in decreased expression of GNAI2 mRNA15170462
D010936Plant ExtractsPlant Extracts results in decreased expression of GNAI2 mRNA23557933
D011441PropylthiouracilPropylthiouracil results in increased expression of GNAI2 mRNA24780913
D011794QuercetinQuercetin results in increased expression of GNAI2 protein9590266
D017382Reactive Oxygen Species[IER3 protein affects the chemical synthesis of Reactive Oxygen Species] which results in increased expression of GNAI220713914
D017382Reactive Oxygen Species[[IER3 protein affects the chemical synthesis of Reactive Oxygen Species] which results in increased expression of GNAI2] which results in decreased chemical synthesis of Cyclic AMP20713914
D012110ReserpineReserpine results in increased expression of GNAI2 mRNA8419537
D012110ReserpineReserpine results in increased expression of GNAI2 protein11264240
C089730rosiglitazone[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in decreased expression of GNAI2 mRNA16054899
D012402RotenoneRotenone affects the reaction [IER3 protein affects the expression of GNAI2 mRNA]20713914
D012643SeleniumSelenium results in increased expression of GNAI2 mRNA19244175
C078903seocalcitolseocalcitol results in increased expression of GNAI2 mRNA12040012
D012822Silicon DioxideSilicon Dioxide results in increased expression of GNAI2 mRNA18685790
C080703SK&F 83959SK&F 83959 results in decreased expression of GNAI2 protein25852303
C017947sodium arsenitesodium arsenite results in increased expression of GNAI2 mRNA20020861
D012999SomanSoman results in increased expression of GNAI2 mRNA19281266
D013311StreptozocinAcetylcysteine inhibits the reaction [Streptozocin results in decreased expression of GNAI2 protein]18441196
D013311Streptozocindiphenyleneiodonium inhibits the reaction [Streptozocin results in decreased expression of GNAI2 protein]18441196
D013311StreptozocinStreptozocin results in decreased expression of GNAI2 protein18441196
D004113Succimer[Succimer co-treated with Magnetite Nanoparticles] results in decreased expression of GNAI2 mRNA26378955
D013739TestosteroneTestosterone affects the expression of GNAI2 mRNA20403060
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of GNAI2 mRNA22298810
D013755Tetradecanoylphorbol Acetate[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of GNAI2 mRNA25613284
D013806TheophyllineTheophylline results in decreased expression of GNAI2 protein15708489
C402769tipifarnibtipifarnib results in decreased expression of GNAI2 mRNA16403772
D014050TolueneToluene affects the expression of GNAI2 mRNA21827849
C052342topiramatetopiramate results in decreased expression of GNAI2 mRNA16979414
C012589trichostatin Atrichostatin A results in increased expression of GNAI2 mRNA15901671
C012589trichostatin A"[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of GNAI2 mRNA"27188386
C012589trichostatin Atrichostatin A affects the expression of GNAI2 mRNA28542535
C012589trichostatin Atrichostatin A results in decreased expression of GNAI2 mRNA24935251|2627250
D014520UrethaneUrethane results in increased expression of GNAI2 mRNA28818685
D014527Uric AcidUric Acid inhibits the reaction [Glucose results in decreased expression of GNAI2 protein]18441196
D014527Uric AcidUric Acid inhibits the reaction [Peroxynitrous Acid results in decreased expression of GNAI2 protein]18055527
D014527Uric AcidUric Acid inhibits the reaction [S-Nitroso-N-Acetylpenicillamine results in decreased expression of GNAI2 protein]16962941
D014635Valproic AcidValproic Acid results in increased expression of GNAI2 mRNA15901671
D014635Valproic AcidValproic Acid results in increased methylation of GNAI2 gene29154799
D014635Valproic AcidValproic Acid results in increased expression of GNAI2 mRNA19136453
D014640VancomycinVancomycin results in decreased expression of GNAI2 mRNA18930951
D014801Vitamin AVitamin A results in increased expression of GNAI2 protein16757122

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0001664G-protein coupled receptor binding-IBA21873635  
GO:0003924GTPase activity-IBA21873635  
GO:0003924GTPase activity-TAS-  
GO:0005515protein binding-IPI15251452  16189514  16263121  16782902  18599439  23773523  
25241761  25416956  
GO:0005525GTP binding-TAS-  
GO:0031683G-protein beta/gamma-subunit complex binding-IBA21873635  
GO:0046872metal ion binding-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO:0001973adenosine receptor signaling pathway-IBA21873635  
GO:0006457protein folding-TAS-  
GO:0007049cell cycle-IEA-  
GO:0007165signal transduction-TAS7961880  9637720  
GO:0007186G-protein coupled receptor signaling pathway-TAS-  
GO:0007188adenylate cyclase-modulating G-protein coupled receptor signaling pathway-IBA21873635  
GO:0007189adenylate cyclase-activating G-protein coupled receptor signaling pathway-IEA-  
GO:0007193adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway-IBA21873635  
GO:0007193adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway-TAS-  
GO:0007194negative regulation of adenylate cyclase activity-TAS9637720  
GO:0007213G-protein coupled acetylcholine receptor signaling pathway-IEA-  
GO:0007214gamma-aminobutyric acid signaling pathway-IBA21873635  
GO:0007584response to nutrient-TAS8587610  
GO:0008283cell proliferation-IEA-  
GO:0030335positive regulation of cell migration-IEA-  
GO:0032930positive regulation of superoxide anion generation-IEA-  
GO:0033864positive regulation of NAD(P)H oxidase activity-IEA-  
GO:0035810positive regulation of urine volume-IEA-  
GO:0035815positive regulation of renal sodium excretion-IEA-  
GO:0045955negative regulation of calcium ion-dependent exocytosis-IEA-  
GO:0046628positive regulation of insulin receptor signaling pathway-IEA-  
GO:0050805negative regulation of synaptic transmission-IEA-  
GO:0051301cell division-IMP17635935  
GO:0051924regulation of calcium ion transport-IEA-  
GO:0070374positive regulation of ERK1 and ERK2 cascade-IEA-  
GO:0140199negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process-IEA-  
GO:1903614negative regulation of protein tyrosine phosphatase activity-IEA-  
GO:1904707positive regulation of vascular smooth muscle cell proliferation-IEA-  
GO:2000179positive regulation of neural precursor cell proliferation-IEA-  
GO:2001234negative regulation of apoptotic signaling pathway-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO:0005654nucleoplasm-IDA-  
GO:0005737cytoplasm-IDA17635935  
GO:0005813centrosome-IDA17635935  
GO:0005829cytosol-IDA-  
GO:0005834heterotrimeric G-protein complex-IBA21873635  
GO:0005886plasma membrane-IDA17635935  
GO:0005886plasma membrane-TAS-  
GO:0016020membrane-HDA19946888  
GO:0030425dendrite-IEA-  
GO:0030496midbody-IDA17635935  
GO:0044297cell body-IEA-  
GO:0045121membrane raft-IEA-  
GO:0070062extracellular exosome-HDA12519789  19056867  19199708  20458337  
GO:1903561extracellular vesicle-HDA24769233  
KEGG ID KEGG Term
hsa04062Chemokine signaling pathway
hsa04360Axon guidance
hsa04530Tight junction
hsa04540Gap junction
hsa04670Leukocyte transendothelial migration
hsa04730Long-term depression
hsa04914Progesterone-mediated oocyte maturation
hsa04916Melanogenesis
hsa04971Gastric acid secretion
hsa05142Chagas disease (American trypanosomiasis)
hsa05145Toxoplasmosis
Reactome ID Reactome Term Evidence
R-HSA-109582HemostasisTAS
R-HSA-111885Opioid SignallingTAS
R-HSA-111885Opioid SignallingIEA
R-HSA-112040G-protein mediated eventsTAS
R-HSA-112040G-protein mediated eventsIEA
R-HSA-112043PLC beta mediated eventsTAS
R-HSA-112043PLC beta mediated eventsIEA
R-HSA-112314Neurotransmitter receptors and postsynaptic signal transmissionTAS
R-HSA-112314Neurotransmitter receptors and postsynaptic signal transmissionIEA
R-HSA-112315Transmission across Chemical SynapsesTAS
R-HSA-112315Transmission across Chemical SynapsesIEA
R-HSA-112316Neuronal SystemTAS
R-HSA-112316Neuronal SystemIEA
R-HSA-1430728MetabolismIEA
R-HSA-1430728MetabolismTAS
R-HSA-162582Signal TransductionTAS
R-HSA-162582Signal TransductionIEA
R-HSA-163685Integration of energy metabolismIEA
R-HSA-163685Integration of energy metabolismTAS
R-HSA-170670Adenylate cyclase inhibitory pathwayTAS
R-HSA-170670Adenylate cyclase inhibitory pathwayIEA
R-HSA-202040G-protein activationTAS
R-HSA-372790Signaling by GPCRTAS
R-HSA-372790Signaling by GPCRIEA
R-HSA-388396GPCR downstream signallingTAS
R-HSA-388396GPCR downstream signallingIEA
R-HSA-390466Chaperonin-mediated protein foldingTAS
R-HSA-391251Protein foldingTAS
R-HSA-392170ADP signalling through P2Y purinoceptor 12TAS
R-HSA-392499Metabolism of proteinsTAS
R-HSA-392518Signal amplificationTAS
R-HSA-400042Adrenaline,noradrenaline inhibits insulin secretionTAS
R-HSA-400042Adrenaline,noradrenaline inhibits insulin secretionIEA
R-HSA-418555G alpha (s) signalling eventsIEA
R-HSA-418594G alpha (i) signalling eventsTAS
R-HSA-418594G alpha (i) signalling eventsIEA
R-HSA-418597G alpha (z) signalling eventsIEA
R-HSA-422356Regulation of insulin secretionIEA
R-HSA-422356Regulation of insulin secretionTAS
R-HSA-6814122Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta foldingTAS
R-HSA-76002Platelet activation, signaling and aggregationTAS
R-HSA-977443GABA receptor activationTAS
R-HSA-977443GABA receptor activationIEA
R-HSA-977444GABA B receptor activationTAS
R-HSA-977444GABA B receptor activationIEA
R-HSA-991365Activation of GABAB receptorsTAS
R-HSA-991365Activation of GABAB receptorsIEA
R-HSA-997269Inhibition of adenylate cyclase pathwayTAS
R-HSA-997269Inhibition of adenylate cyclase pathwayIEA

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
28420501Bioinformatics analysis of gene expression profiles in B cells of postmenopausal osteoporosis patients. (2017 Apr)Ma MTaiwan J Obstet Gynecol