| C060229 | 1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione | "1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [[[6alpha-ethyl-23(S)-methylcholic acid binds to and results in increased activity of GPBAR1 protein] which results in increased activity of GNAS protein] which results in increased hydrolysis of Phosphatidylinositols]" | 23022524 |
| C060229 | 1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione | "1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [[[Oleanolic Acid binds to and results in increased activity of GPBAR1 protein] which results in increased activity of GNAS protein] which results in increased hydrolysis of Phosphatidylinositols]" | 23022524 |
| C029790 | 2,2',3',4,4',5-hexachlorobiphenyl | "2,2',3',4,4',5-hexachlorobiphenyl results in decreased expression of GNAS mRNA" | 23829299 |
| C029497 | 2,3-bis(3'-hydroxybenzyl)butyrolactone | "2,3-bis(3'-hydroxybenzyl)butyrolactone results in decreased expression of GNAS mRNA" | 19167446 |
| C016392 | 3,3'-diindolylmethane | "3,3'-diindolylmethane inhibits the reaction [Estradiol results in decreased expression of GNAS mRNA]" | 11179685 |
| C549543 | 3-hydroxy-4-prenyl-5-methoxystilbene-2-carboxylic acid | 3-hydroxy-4-prenyl-5-methoxystilbene-2-carboxylic acid analog results in decreased expression of GNAS mRNA | 25716159 |
| C110258 | 4,4,',4'',4'''-(carbonylbis(imino-5,1,3-benzenetriylbis(carbonylimino)))tetrakis(benzene-1,3-disulfonate) | "4,4,',4'',4'''-(carbonylbis(imino-5,1,3-benzenetriylbis(carbonylimino)))tetrakis(benzene-1,3-disulfonate) inhibits the reaction [[[6alpha-ethyl-23(S)-methylcholic acid binds to and results in increased activity of GPBAR1 protein] which results in increased activity of GNAS protein] which results in increased hydrolysis of Phosphatidylinositols]" | 23022524 |
| C110258 | 4,4,',4'',4'''-(carbonylbis(imino-5,1,3-benzenetriylbis(carbonylimino)))tetrakis(benzene-1,3-disulfonate) | "4,4,',4'',4'''-(carbonylbis(imino-5,1,3-benzenetriylbis(carbonylimino)))tetrakis(benzene-1,3-disulfonate) inhibits the reaction [[[Oleanolic Acid binds to and results in increased activity of GPBAR1 protein] which results in increased activity of GNAS protein] which results in increased hydrolysis of Phosphatidylinositols]" | 23022524 |
| C110258 | 4,4,',4'',4'''-(carbonylbis(imino-5,1,3-benzenetriylbis(carbonylimino)))tetrakis(benzene-1,3-disulfonate) | "4,4,',4'',4'''-(carbonylbis(imino-5,1,3-benzenetriylbis(carbonylimino)))tetrakis(benzene-1,3-disulfonate) results in decreased activity of GNAS protein" | 23022524 |
| C110258 | 4,4,',4'',4'''-(carbonylbis(imino-5,1,3-benzenetriylbis(carbonylimino)))tetrakis(benzene-1,3-disulfonate) | "4,4,',4'',4'''-(carbonylbis(imino-5,1,3-benzenetriylbis(carbonylimino)))tetrakis(benzene-1,3-disulfonate) results in decreased activity of GNAS protein" | 19654912 |
| C459179 | 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide | "[NOG protein co-treated with entinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of GNAS mRNA" | 27188386 |
| C459179 | 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide | "[NOG protein co-treated with panobinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of GNAS mRNA" | 27188386 |
| C459179 | 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide | "[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of GNAS mRNA" | 27188386 |
| C459179 | 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide | "[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of GNAS mRNA" | 27188386 |
| C459179 | 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide | "[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of GNAS mRNA" | 27188386 |
| C027576 | 4-hydroxy-2-nonenal | 4-hydroxy-2-nonenal results in decreased expression of GNAS mRNA | 12419474 |
| C516138 | (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine | "[NOG protein co-treated with entinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of GNAS mRNA" | 27188386 |
| C516138 | (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine | "[NOG protein co-treated with panobinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of GNAS mRNA" | 27188386 |
| C516138 | (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine | "[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of GNAS mRNA" | 27188386 |
| C516138 | (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine | "[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of GNAS mRNA" | 27188386 |
| C516138 | (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine | "[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of GNAS mRNA" | 27188386 |
| C545501 | 6alpha-ethyl-23(S)-methylcholic acid | "1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [[[6alpha-ethyl-23(S)-methylcholic acid binds to and results in increased activity of GPBAR1 protein] which results in increased activity of GNAS protein] which results in increased hydrolysis of Phosphatidylinositols]" | 23022524 |
| C545501 | 6alpha-ethyl-23(S)-methylcholic acid | "4,4,',4'',4'''-(carbonylbis(imino-5,1,3-benzenetriylbis(carbonylimino)))tetrakis(benzene-1,3-disulfonate) inhibits the reaction [[[6alpha-ethyl-23(S)-methylcholic acid binds to and results in increased activity of GPBAR1 protein] which results in increased activity of GNAS protein] which results in increased hydrolysis of Phosphatidylinositols]" | 23022524 |
| C545501 | 6alpha-ethyl-23(S)-methylcholic acid | [6alpha-ethyl-23(S)-methylcholic acid binds to and results in increased activity of GPBAR1 protein] which results in increased activity of GNAS protein | 23022524 |
| C545501 | 6alpha-ethyl-23(S)-methylcholic acid | [[6alpha-ethyl-23(S)-methylcholic acid binds to and results in increased activity of GPBAR1 protein] which results in increased activity of GNAS protein] which results in increased abundance of Calcium | 23022524 |
| C545501 | 6alpha-ethyl-23(S)-methylcholic acid | [[6alpha-ethyl-23(S)-methylcholic acid binds to and results in increased activity of GPBAR1 protein] which results in increased activity of GNAS protein] which results in increased abundance of Cyclic AMP | 23022524 |
| C545501 | 6alpha-ethyl-23(S)-methylcholic acid | [[6alpha-ethyl-23(S)-methylcholic acid binds to and results in increased activity of GPBAR1 protein] which results in increased activity of GNAS protein] which results in increased hydrolysis of Phosphatidylinositols | 23022524 |
| D000242 | Cyclic AMP | GNAS protein promotes the reaction [[cicaprost results in increased activity of PTGIR protein] which results in increased abundance of Cyclic AMP] | 11895442 |
| D000242 | Cyclic AMP | [[GNAS protein results in increased susceptibility to citronellal] which results in increased activity of OLFR49 protein] which results in increased abundance of Cyclic AMP | 15598656 |
| D000242 | Cyclic AMP | [[6alpha-ethyl-23(S)-methylcholic acid binds to and results in increased activity of GPBAR1 protein] which results in increased activity of GNAS protein] which results in increased abundance of Cyclic AMP | 23022524 |
| D000242 | Cyclic AMP | [[Oleanolic Acid binds to and results in increased activity of GPBAR1 protein] which results in increased activity of GNAS protein] which results in increased abundance of Cyclic AMP | 23022524 |
| D016604 | Aflatoxin B1 | Aflatoxin B1 results in decreased methylation of GNAS gene | 27153756 |
| D000526 | Alprenolol | [Alprenolol co-treated with ADRB2 protein] results in increased expression of GNAS protein | 10455254 |
| C032311 | aluminum fluoride | aluminum fluoride results in increased activity of GNAS protein | 7961906 |
| D000638 | Amiodarone | Amiodarone results in increased expression of GNAS mRNA | 19774075 |
| D000643 | Ammonium Chloride | Ammonium Chloride affects the expression of GNAS mRNA | 16483693 |
| D018501 | Antirheumatic Agents | Antirheumatic Agents results in increased expression of GNAS mRNA | 24449571 |
| C015001 | arsenite | arsenite affects the methylation of GNAS promoter | 23974009 |
| D001280 | Atrazine | Atrazine results in decreased expression of GNAS mRNA | 25929836 |
| C028559 | bathocuproine sulfonate | [pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of GNAS mRNA | 15477007 |
| D004958 | Estradiol | "3,3'-diindolylmethane inhibits the reaction [Estradiol results in decreased expression of GNAS mRNA]" | 11179685 |
| D004958 | Estradiol | Estradiol results in decreased expression of GNAS mRNA | 11179685 |
| D004958 | Estradiol | Tetrachlorodibenzodioxin inhibits the reaction [Estradiol results in decreased expression of GNAS mRNA] | 11179685 |
| D017298 | Bisoprolol | Bisoprolol results in increased expression of GNAS mRNA | 20668454 |
| C006780 | bisphenol A | bisphenol A results in decreased methylation of GNAS promoter | 27271280 |
| C006780 | bisphenol A | bisphenol A results in increased expression of GNAS mRNA | 29275510 |
| C006780 | bisphenol A | bisphenol A affects the expression of GNAS mRNA | 21636974 |
| C006780 | bisphenol A | bisphenol A results in decreased methylation of GNAS promoter | 27312807 |
| C006780 | bisphenol A | bisphenol A results in increased expression of GNAS mRNA | 26063408 |
| C006780 | bisphenol A | bisphenol A results in increased methylation of GNAS promoter | 27312807 |
| C006780 | bisphenol A | bisphenol A results in increased expression of GNAS mRNA | 25181051 |
| C006780 | bisphenol A | bisphenol A results in increased methylation of GNAS gene | 28505145 |
| D020122 | tert-Butylhydroperoxide | tert-Butylhydroperoxide results in decreased expression of GNAS mRNA | 12419474 |
| C018475 | butyraldehyde | butyraldehyde results in decreased expression of GNAS mRNA | 26079696 |
| D002110 | Caffeine | Caffeine results in decreased expression of GNAS protein | 15708489 |
| D002118 | Calcium | [[6alpha-ethyl-23(S)-methylcholic acid binds to and results in increased activity of GPBAR1 protein] which results in increased activity of GNAS protein] which results in increased abundance of Calcium | 23022524 |
| D002118 | Calcium | [[Oleanolic Acid binds to and results in increased activity of GPBAR1 protein] which results in increased activity of GNAS protein] which results in increased abundance of Calcium | 23022524 |
| D002220 | Carbamazepine | Carbamazepine affects the expression of GNAS mRNA | 24752500 |
| C043211 | carvedilol | [carvedilol co-treated with ADRB2 protein] results in increased expression of GNAS protein | 10455254 |
| C043211 | carvedilol | carvedilol results in increased expression of GNAS mRNA | 20668454 |
| D000068579 | Celecoxib | Celecoxib results in increased expression of GNAS mRNA | 28201806 |
| D002713 | Chlorine | [Ozone co-treated with Chlorine] results in decreased expression of GNAS mRNA | 18636392 |
| D020111 | Chlorodiphenyl (54% Chlorine) | Chlorodiphenyl (54% Chlorine) results in decreased expression of GNAS mRNA | 23650126 |
| C100187 | chloropicrin | chloropicrin results in decreased expression of GNAS mRNA | 26352163 |
| D002737 | Chloroprene | Chloroprene results in increased expression of GNAS mRNA | 23125180 |
| D002772 | Cholera Toxin | Cholera Toxin promotes the reaction [GNAS protein modified form binds to Guanosine Triphosphate] | 17136323 |
| D002772 | Cholera Toxin | Cholera Toxin results in increased activity of and results in increased ADP-ribosylation of GNAS protein | 17136323 |
| D002784 | Cholesterol | Cholesterol inhibits the reaction [Progesterone results in increased expression of GNAS protein] | 19221014 |
| C043867 | cicaprost | cicaprost promotes the reaction [PTGIR protein binds to GNAS protein] | 11895442 |
| C043867 | cicaprost | GNAS protein promotes the reaction [[cicaprost results in increased activity of PTGIR protein] which results in increased abundance of Cyclic AMP] | 11895442 |
| C108217 | citronellal | Egtazic Acid inhibits the reaction [GNAS protein results in increased susceptibility to citronellal] | 15598656 |
| C108217 | citronellal | Egtazic Acid inhibits the reaction [[GNAS protein results in increased susceptibility to citronellal] which results in increased activity of OLFR49 protein] | 15598656 |
| C108217 | citronellal | GNAS protein results in increased susceptibility to citronellal | 15598656 |
| C108217 | citronellal | [GNAS protein results in increased susceptibility to citronellal] which results in increased activity of OLFR49 protein | 15598656 |
| C108217 | citronellal | [[GNAS protein results in increased susceptibility to citronellal] which results in increased activity of OLFR49 protein] which results in increased abundance of Cyclic AMP | 15598656 |
| D003024 | Clozapine | Clozapine results in decreased expression of GNAS mRNA | 15860345 |
| C018021 | cobaltous chloride | cobaltous chloride results in decreased expression of GNAS mRNA | 19320972 |
| D019327 | Copper Sulfate | Copper Sulfate results in decreased activity of GNAS protein | 15546818 |
| D019327 | Copper Sulfate | Copper Sulfate results in decreased activity of GNAS protein | 15546818 |
| D019327 | Copper Sulfate | Copper Sulfate inhibits the reaction [Guanosine 5'-O-(3-Thiotriphosphate) binds to GNAS protein] | 15546818 |
| D019327 | Copper Sulfate | Copper Sulfate inhibits the reaction [Guanosine Diphosphate binds to GNAS protein] | 15546818 |
| D019327 | Copper Sulfate | Copper Sulfate inhibits the reaction [Guanosine Triphosphate binds to GNAS protein] | 15546818 |
| D016572 | Cyclosporine | Cyclosporine results in decreased methylation of GNAS promoter | 27989131 |
| D003907 | Dexamethasone | Dexamethasone results in increased expression of GNAS mRNA | 7730645 |
| D003993 | Dibutyl Phthalate | Dibutyl Phthalate results in decreased expression of GNAS mRNA | 21266533 |
| D002945 | Cisplatin | Cisplatin inhibits the reaction [GNAS protein results in increased expression of XIAP mRNA] | 21255191 |
| D002945 | Cisplatin | GNAS protein inhibits the reaction [Cisplatin results in increased cleavage of CASP3 protein] | 21255191 |
| D002945 | Cisplatin | [GNAS protein results in increased expression of XIAP protein] which results in decreased susceptibility to Cisplatin | 21255191 |
| D002945 | Cisplatin | GNAS results in decreased susceptibility to Cisplatin | 21849418 |
| D004008 | Diclofenac | Diclofenac affects the expression of GNAS mRNA | 24752500 |
| D004051 | Diethylhexyl Phthalate | Diethylhexyl Phthalate affects the expression of GNAS mRNA | 21636974 |
| D004280 | Dobutamine | GNAS gene SNP results in increased susceptibility to Dobutamine | 19542315 |
| D004317 | Doxorubicin | Doxorubicin affects the expression of GNAS protein | 29385562 |
| D004317 | Doxorubicin | [GNAS protein results in increased expression of XIAP protein] which results in decreased susceptibility to Doxorubicin | 21255191 |
| D004317 | Doxorubicin | Doxorubicin results in decreased expression of GNAS mRNA | 15353854 |
| D004533 | Egtazic Acid | Egtazic Acid inhibits the reaction [GNAS protein results in increased susceptibility to citronellal] | 15598656 |
| D004533 | Egtazic Acid | Egtazic Acid inhibits the reaction [[GNAS protein results in increased susceptibility to citronellal] which results in increased activity of OLFR49 protein] | 15598656 |
| D004533 | Egtazic Acid | Egtazic Acid inhibits the reaction [GNAS protein results in increased susceptibility to Isoproterenol] | 15598656 |
| C118739 | entinostat | entinostat results in increased expression of GNAS mRNA | 26272509 |
| C118739 | entinostat | "[NOG protein co-treated with entinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of GNAS mRNA" | 27188386 |
| D004785 | Environmental Pollutants | Environmental Pollutants results in decreased expression of GNAS mRNA | 12655031 |
| D005020 | Ethyl Methanesulfonate | Ethyl Methanesulfonate results in decreased expression of GNAS mRNA | 23649840 |
| D005038 | Ethylnitrosourea | Ethylnitrosourea results in increased mutagenesis of GNAS gene | 16724327 |
| D018120 | Finasteride | Finasteride results in increased expression of GNAS mRNA | 24136188 |
| D005419 | Flavonoids | Flavonoids results in decreased expression of GNAS mRNA | 18035473 |
| D005473 | Fluoxetine | Fluoxetine results in decreased expression of GNAS mRNA | 1426031 |
| D005473 | Fluoxetine | Fluoxetine results in increased expression of GNAS mRNA | 21852994 |
| D005492 | Folic Acid | [Folic Acid co-treated with sodium arsenite] results in increased methylation of GNAS mRNA | 22959928 |
| C056933 | fumonisin B1 | fumonisin B1 results in increased expression of GNAS mRNA | 16221962 |
| D019833 | Genistein | [Genistein co-treated with Methoxychlor] results in increased expression of GNAS mRNA | 21782745 |
| C002963 | geranylgeranyl pyrophosphate | geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin results in decreased expression of GNAS protein] | 22144680 |
| D006153 | Guanosine Diphosphate | Copper Sulfate inhibits the reaction [Guanosine Diphosphate binds to GNAS protein] | 15546818 |
| D006153 | Guanosine Diphosphate | tetrafluoroaluminate promotes the reaction [Guanosine Diphosphate binds to GNAS protein] | 15546818 |
| D006153 | Guanosine Diphosphate | Zinc Sulfate inhibits the reaction [Guanosine Diphosphate binds to GNAS protein] | 15546818 |
| D016244 | Guanosine 5'-O-(3-Thiotriphosphate) | Copper Sulfate inhibits the reaction [Guanosine 5'-O-(3-Thiotriphosphate) binds to GNAS protein] | 15546818 |
| D016244 | Guanosine 5'-O-(3-Thiotriphosphate) | Zinc Sulfate inhibits the reaction [Guanosine 5'-O-(3-Thiotriphosphate) binds to GNAS protein] | 15546818 |
| D006160 | Guanosine Triphosphate | Cholera Toxin promotes the reaction [GNAS protein modified form binds to Guanosine Triphosphate] | 17136323 |
| D006160 | Guanosine Triphosphate | Copper Sulfate inhibits the reaction [Guanosine Triphosphate binds to GNAS protein] | 15546818 |
| D006160 | Guanosine Triphosphate | Zinc Sulfate inhibits the reaction [Guanosine Triphosphate binds to GNAS protein] | 15546818 |
| D006220 | Haloperidol | Haloperidol results in decreased expression of GNAS mRNA | 15860345 |
| D006861 | Hydrogen Peroxide | Hydrogen Peroxide results in decreased expression of GNAS mRNA | 12419474 |
| D006861 | Hydrogen Peroxide | Hydrogen Peroxide results in decreased secretion of GNAS mRNA | 21179422 |
| C026777 | ICI 118551 | [ICI 118551 co-treated with ADRB2 protein] results in increased expression of GNAS protein | 10455254 |
| C026777 | ICI 118551 | ICI 118551 results in increased expression of GNAS protein | 10455254 |
| D007213 | Indomethacin | Indomethacin results in decreased expression of GNAS protein | 15579502 |
| D007545 | Isoproterenol | Egtazic Acid inhibits the reaction [GNAS protein results in increased susceptibility to Isoproterenol] | 15598656 |
| D007545 | Isoproterenol | GNAS protein results in increased susceptibility to Isoproterenol | 15598656 |
| D007545 | Isoproterenol | GNAS protein affects the susceptibility to [Potassium Chloride co-treated with Isoproterenol] | 10696522 |
| D007545 | Isoproterenol | Isoproterenol affects the expression of and affects the localization of GNAS protein | 12376418 |
| C561695 | (+)-JQ1 compound | GNAS protein results in decreased susceptibility to (+)-JQ1 compound | 23430699 |
| C561695 | (+)-JQ1 compound | (+)-JQ1 compound results in decreased expression of GNAS mRNA | 23086925 |
| D007854 | Lead | Lead affects the expression of GNAS mRNA | 28903495 |
| D007854 | Lead | Lead affects the splicing of GNAS mRNA | 28903495 |
| D007854 | Lead | Lead results in increased expression of GNAS mRNA | 19921347 |
| C042720 | mercuric bromide | mercuric bromide results in increased expression of GNAS mRNA | 26272509 |
| D008731 | Methoxychlor | [Genistein co-treated with Methoxychlor] results in increased expression of GNAS mRNA | 21782745 |
| D008731 | Methoxychlor | Methoxychlor results in decreased expression of GNAS mRNA | 23303685 |
| D008731 | Methoxychlor | Methoxychlor results in increased expression of GNAS mRNA | 21782745 |
| C004925 | methylmercuric chloride | methylmercuric chloride results in decreased expression of GNAS protein | 25809596 |
| C004925 | methylmercuric chloride | methylmercuric chloride results in increased expression of GNAS mRNA | 28001369 |
| D008798 | Mevalonic Acid | Mevalonic Acid inhibits the reaction [Simvastatin results in decreased expression of GNAS protein] | 22144680 |
| D009020 | Morphine | Morphine results in increased expression of GNAS mRNA | 17893922 |
| D009020 | Morphine | Morphine results in increased expression of GNAS protein | 17893922 |
| D037742 | Nanotubes, Carbon | "Nanotubes, Carbon results in increased expression of GNAS mRNA" | 25620056 |
| C051752 | nefazodone | nefazodone results in decreased expression of GNAS mRNA | 24136188 |
| C012655 | nimesulide | nimesulide results in decreased expression of GNAS mRNA | 24136188 |
| D009638 | Norepinephrine | Norepinephrine promotes the reaction [ADRB1 protein results in increased activity of GNAS protein] | 17200720 |
| D009828 | Oleanolic Acid | "1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [[[Oleanolic Acid binds to and results in increased activity of GPBAR1 protein] which results in increased activity of GNAS protein] which results in increased hydrolysis of Phosphatidylinositols]" | 23022524 |
| D009828 | Oleanolic Acid | "4,4,',4'',4'''-(carbonylbis(imino-5,1,3-benzenetriylbis(carbonylimino)))tetrakis(benzene-1,3-disulfonate) inhibits the reaction [[[Oleanolic Acid binds to and results in increased activity of GPBAR1 protein] which results in increased activity of GNAS protein] which results in increased hydrolysis of Phosphatidylinositols]" | 23022524 |
| D009828 | Oleanolic Acid | [Oleanolic Acid binds to and results in increased activity of GPBAR1 protein] which results in increased activity of GNAS protein | 23022524 |
| D009828 | Oleanolic Acid | [[Oleanolic Acid binds to and results in increased activity of GPBAR1 protein] which results in increased activity of GNAS protein] which results in increased abundance of Calcium | 23022524 |
| D009828 | Oleanolic Acid | [[Oleanolic Acid binds to and results in increased activity of GPBAR1 protein] which results in increased activity of GNAS protein] which results in increased abundance of Cyclic AMP | 23022524 |
| D009828 | Oleanolic Acid | [[Oleanolic Acid binds to and results in increased activity of GPBAR1 protein] which results in increased activity of GNAS protein] which results in increased hydrolysis of Phosphatidylinositols | 23022524 |
| D010100 | Oxygen | Oxygen deficiency results in increased expression of GNAS mRNA | 20862257 |
| D010100 | Oxygen | Oxygen deficiency results in decreased expression of GNAS protein | 10192281 |
| D010126 | Ozone | Ozone results in decreased expression of GNAS mRNA | 24336422 |
| D010126 | Ozone | [Ozone co-treated with Chlorine] results in decreased expression of GNAS mRNA | 18636392 |
| C496932 | panobinostat | "[NOG protein co-treated with panobinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of GNAS mRNA" | 27188386 |
| C496932 | panobinostat | panobinostat results in increased expression of GNAS mRNA | 26272509 |
| D010269 | Paraquat | Paraquat results in increased expression of GNAS mRNA | 16797015 |
| D010269 | Paraquat | Paraquat affects the expression of GNAS mRNA | 15206577 |
| D010424 | Pentobarbital | Pentobarbital affects the expression of GNAS mRNA | 12199159 |
| D010622 | Phencyclidine | Phencyclidine results in increased expression of GNAS mRNA | 12105081 |
| D010634 | Phenobarbital | Phenobarbital results in increased expression of GNAS mRNA | 12082028 |
| D010656 | Phenylephrine | GNAS protein affects the susceptibility to Phenylephrine | 10696522 |
| D010662 | Phenylmercuric Acetate | "[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of GNAS mRNA" | 27188386 |
| D010662 | Phenylmercuric Acetate | Phenylmercuric Acetate affects the expression of GNAS mRNA | 26272509 |
| D010716 | Phosphatidylinositols | "1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [[[6alpha-ethyl-23(S)-methylcholic acid binds to and results in increased activity of GPBAR1 protein] which results in increased activity of GNAS protein] which results in increased hydrolysis of Phosphatidylinositols]" | 23022524 |
| D010716 | Phosphatidylinositols | "1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [[[Oleanolic Acid binds to and results in increased activity of GPBAR1 protein] which results in increased activity of GNAS protein] which results in increased hydrolysis of Phosphatidylinositols]" | 23022524 |
| D010716 | Phosphatidylinositols | "4,4,',4'',4'''-(carbonylbis(imino-5,1,3-benzenetriylbis(carbonylimino)))tetrakis(benzene-1,3-disulfonate) inhibits the reaction [[[6alpha-ethyl-23(S)-methylcholic acid binds to and results in increased activity of GPBAR1 protein] which results in increased activity of GNAS protein] which results in increased hydrolysis of Phosphatidylinositols]" | 23022524 |
| D010716 | Phosphatidylinositols | "4,4,',4'',4'''-(carbonylbis(imino-5,1,3-benzenetriylbis(carbonylimino)))tetrakis(benzene-1,3-disulfonate) inhibits the reaction [[[Oleanolic Acid binds to and results in increased activity of GPBAR1 protein] which results in increased activity of GNAS protein] which results in increased hydrolysis of Phosphatidylinositols]" | 23022524 |
| D010716 | Phosphatidylinositols | [[6alpha-ethyl-23(S)-methylcholic acid binds to and results in increased activity of GPBAR1 protein] which results in increased activity of GNAS protein] which results in increased hydrolysis of Phosphatidylinositols | 23022524 |
| D010716 | Phosphatidylinositols | [[Oleanolic Acid binds to and results in increased activity of GPBAR1 protein] which results in increased activity of GNAS protein] which results in increased hydrolysis of Phosphatidylinositols | 23022524 |
| C006253 | pirinixic acid | pirinixic acid results in increased expression of GNAS mRNA | 16221962|1830175 |
| C006253 | pirinixic acid | pirinixic acid results in increased expression of GNAS mRNA | 16940010 |
| D011189 | Potassium Chloride | GNAS protein affects the susceptibility to [Potassium Chloride co-treated with Isoproterenol] | 10696522 |
| D011285 | Pregnenolone Carbonitrile | Pregnenolone Carbonitrile results in increased expression of GNAS mRNA | 22698814 |
| D011374 | Progesterone | CAV3 mutant form inhibits the reaction [Progesterone results in increased expression of GNAS protein] | 19221014 |
| D011374 | Progesterone | Progesterone results in increased expression of GNAS protein | 19221014 |
| D011374 | Progesterone | CAV3 mutant form inhibits the reaction [Progesterone results in increased expression of GNAS protein] | 19221014 |
| D011374 | Progesterone | Cholesterol inhibits the reaction [Progesterone results in increased expression of GNAS protein] | 19221014 |
| D011374 | Progesterone | Progesterone results in increased expression of GNAS protein | 19221014 |
| D011374 | Progesterone | Progesterone results in increased expression of GNAS protein | 15469997 |
| D011433 | Propranolol | [Propranolol co-treated with ADRB2 protein] results in increased expression of GNAS protein | 10455254 |
| D011433 | Propranolol | Propranolol results in increased expression of GNAS mRNA | 20668454 |
| D011441 | Propylthiouracil | Propylthiouracil results in increased expression of GNAS mRNA | 24780913 |
| C020972 | pyrrolidine dithiocarbamic acid | [pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of GNAS mRNA | 15477007 |
| D012110 | Reserpine | Reserpine results in decreased expression of GNAS protein alternative form | 1336118 |
| D012110 | Reserpine | Reserpine results in increased expression of GNAS mRNA | 8419537 |
| D012110 | Reserpine | Reserpine results in increased expression of GNAS protein | 11264240 |
| C059514 | resveratrol | resveratrol results in decreased expression of GNAS mRNA | 22610192 |
| D012524 | Sarin | Sarin results in decreased expression of GNAS mRNA | 19522546 |
| D012643 | Selenium | [Selenium co-treated with Vitamin E] results in decreased expression of GNAS mRNA | 19244175 |
| D012643 | Selenium | Selenium results in decreased expression of GNAS mRNA | 19244175 |
| D012822 | Silicon Dioxide | Silicon Dioxide results in increased expression of GNAS mRNA | 18685790 |
| D019821 | Simvastatin | geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin results in decreased expression of GNAS protein] | 22144680 |
| D019821 | Simvastatin | Mevalonic Acid inhibits the reaction [Simvastatin results in decreased expression of GNAS protein] | 22144680 |
| D019821 | Simvastatin | Simvastatin results in decreased expression of GNAS protein | 22144680 |
| D019821 | Simvastatin | Simvastatin results in increased expression of GNAS mRNA | 22144680 |
| C017947 | sodium arsenite | [Folic Acid co-treated with sodium arsenite] results in increased methylation of GNAS mRNA | 22959928 |
| D012999 | Soman | Soman results in increased expression of GNAS mRNA | 19281266 |
| D013467 | Sulindac | Sulindac results in increased expression of GNAS mRNA | 24136188 |
| D013726 | Terbutaline | Terbutaline affects the localization of GNAS protein | 12376418 |
| D013726 | Terbutaline | Terbutaline results in increased localization of GNAS protein alternative form | 12376418 |
| D013749 | Tetrachlorodibenzodioxin | Tetrachlorodibenzodioxin inhibits the reaction [Estradiol results in decreased expression of GNAS mRNA] | 11179685 |
| D013749 | Tetrachlorodibenzodioxin | Tetrachlorodibenzodioxin affects the expression of GNAS mRNA | 21570461|2637764 |
| C050992 | tetrafluoroaluminate | tetrafluoroaluminate promotes the reaction [Guanosine Diphosphate binds to GNAS protein] | 15546818 |
| D013806 | Theophylline | Theophylline results in decreased expression of GNAS protein | 15708489 |
| C009495 | titanium dioxide | titanium dioxide results in decreased expression of GNAS mRNA | 23557971 |
| D014028 | Tobacco Smoke Pollution | Tobacco Smoke Pollution results in increased expression of GNAS mRNA | 28065790 |
| D014212 | Tretinoin | Tretinoin results in decreased expression of GNAS mRNA | 21934132 |
| D014241 | Trichloroethylene | PPARA protein inhibits the reaction [Trichloroethylene results in decreased expression of GNAS mRNA] | 15363585 |
| C012589 | trichostatin A | "[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of GNAS mRNA" | 27188386 |
| C012589 | trichostatin A | trichostatin A results in increased expression of GNAS mRNA | 24935251|2627250 |
| C016805 | tris(1,3-dichloro-2-propyl)phosphate | "tris(1,3-dichloro-2-propyl)phosphate results in increased expression of GNAS mRNA" | 26179874 |
| D014415 | Tunicamycin | Tunicamycin results in decreased expression of GNAS mRNA | 17127020 |
| D014635 | Valproic Acid | "[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of GNAS mRNA" | 27188386 |
| D014635 | Valproic Acid | Valproic Acid affects the expression of GNAS mRNA | 23179753 |
| D014635 | Valproic Acid | Valproic Acid results in increased expression of GNAS mRNA | 24383497|2493525 |
| D014635 | Valproic Acid | Valproic Acid affects the expression of GNAS mRNA | 17292431 |
| D001335 | Vehicle Emissions | Vehicle Emissions results in increased methylation of GNAS gene | 25560391 |
| D014810 | Vitamin E | [Selenium co-treated with Vitamin E] results in decreased expression of GNAS mRNA | 19244175 |
| C111237 | vorinostat | vorinostat results in decreased expression of GNAS mRNA | 27188386 |
| D019287 | Zinc Sulfate | Zinc Sulfate results in decreased activity of GNAS protein | 15546818 |
| D019287 | Zinc Sulfate | Zinc Sulfate results in decreased activity of GNAS protein | 15546818 |
| D019287 | Zinc Sulfate | Zinc Sulfate inhibits the reaction [Guanosine 5'-O-(3-Thiotriphosphate) binds to GNAS protein] | 15546818 |
| D019287 | Zinc Sulfate | Zinc Sulfate inhibits the reaction [Guanosine Diphosphate binds to GNAS protein] | 15546818 |
| D019287 | Zinc Sulfate | Zinc Sulfate inhibits the reaction [Guanosine Triphosphate binds to GNAS protein] | 15546818 |