Gene info: ID 283

Gene: ANG

GENE ID: 283

Synonyms: ALS9|HEL168|RAA1|RNASE4|RNASE5

Description: angiogenin

Gene type: protein-coding

Location: 14q11.2

dbXrefs: Ensembl:ENSG00000214274 MIM:105850 Vega:OTTHUMG00000029576 UniprotKB:P03950

RefSeq: NG_008717.2

Retrived from: PubMed

SNPs: 0 ANCO-SNPs

Phenotype: ND|AD

# Publications: 43

Sherlock p-value : NA (AD) NA (ND) (Frontal_Cortex)

Pascal p-value : NA (AD) NA (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol	Pearson Correlation Coefficient
RNASE4	0.798
PLP2	0.784
AGTRAP	0.783
S100A10	0.779
ADAMTSL4	0.773
RARRES3	0.764
BCL2L12	0.754
STAT5A	0.751
MVP	0.75
APOBEC3F	0.746

Top 10 negatively co-expressed genes

Gene Symbol	Pearson Correlation Coefficient
ABCC12	-0.577
KCNIP3	-0.562
WNT7A	-0.562
MARCH4	-0.56
NEUROD6	-0.554
ADRA1D	-0.547
KIT	-0.544
SLC7A4	-0.543
GPR61	-0.534
PPEF1	-0.528

ID	Drug Name	Drug Type	CAS Num	Status	Role
DB03088	Pidolic Acid	Small Molecule	98-79-3	Approved\|Experimental\|Investigational	Target
DB04272	Citric Acid	Small Molecule	77-92-9	Approved\|Nutraceutical	Target
DB09130	Copper	Small Molecule	7440-50-8	Approved\|Investigational	Enzyme

ID	Drug Name	Action	PubMed
C028474	1,4-bis(2-(3,5-dichloropyridyloxy))benzene	"1,4-bis(2-(3,5-dichloropyridyloxy))benzene affects the expression of ANG mRNA"	18281256
C028474	1,4-bis(2-(3,5-dichloropyridyloxy))benzene	"1,4-bis(2-(3,5-dichloropyridyloxy))benzene results in decreased expression of ANG mRNA"	28903501
C032668	1-nitropyrene	1-nitropyrene results in decreased expression of ANG mRNA	19041380
C511295	2,2',4,4'-tetrabromodiphenyl ether	"2,2',4,4'-tetrabromodiphenyl ether results in decreased expression of ANG mRNA"	23146750
C016392	3,3'-diindolylmethane	"3,3'-diindolylmethane results in decreased expression of ANG mRNA"	16192472
C459179	4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide	"[NOG protein co-treated with entinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ANG mRNA"	27188386
C459179	4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide	"[NOG protein co-treated with panobinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ANG mRNA"	27188386
C459179	4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide	"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ANG mRNA"	27188386
C517041	(4-amino-1,4-dihydro-3-(2-pyridyl)-5-thioxo-1,2,4-triazole)copper(II)	"(4-amino-1,4-dihydro-3-(2-pyridyl)-5-thioxo-1,2,4-triazole)copper(II) results in increased expression of ANG mRNA"	19561079
C029370	4-toluidine	4-toluidine results in decreased expression of ANG mRNA	27638505
C516138	(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine	"[NOG protein co-treated with entinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ANG mRNA"	27188386
C516138	(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine	"[NOG protein co-treated with panobinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ANG mRNA"	27188386
C516138	(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine	"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ANG mRNA"	27188386
D000082	Acetaminophen	Acetaminophen affects the expression of ANG mRNA	21420995
D000082	Acetaminophen	Acetaminophen results in decreased expression of ANG mRNA	11793227\|2906747
D000082	Acetaminophen	Acetaminophen affects the expression of ANG mRNA	17562736
D000111	Acetylcysteine	Acetylcysteine inhibits the reaction [Cadmium Chloride results in decreased secretion of ANG protein]	26138014
D016604	Aflatoxin B1	Aflatoxin B1 affects the expression of ANG protein	20106945
D016604	Aflatoxin B1	Aflatoxin B1 results in decreased expression of ANG mRNA	27153756
D016604	Aflatoxin B1	Aflatoxin B1 results in decreased methylation of ANG gene	27153756
D000393	Air Pollutants	Air Pollutants analog results in decreased expression of ANG mRNA	21757418
D001280	Atrazine	Atrazine results in increased expression of ANG mRNA	22378314
D001379	Azathioprine	Azathioprine results in decreased expression of ANG mRNA	22623647
D001564	Benzo(a)pyrene	Benzo(a)pyrene metabolite results in decreased expression of ANG mRNA	26314263
D004958	Estradiol	[Estradiol co-treated with Tetrachlorodibenzodioxin] results in decreased expression of ANG mRNA	19619570
D004958	Estradiol	Estradiol results in decreased expression of ANG mRNA	20106945
D004958	Estradiol	Estradiol results in increased expression of ANG mRNA	19429434\|1961957
D004958	Estradiol	Estradiol results in decreased expression of ANG mRNA	16192472
C006780	bisphenol A	bisphenol A results in increased expression of ANG mRNA	25181051
C005961	bis(tri-n-butyltin)oxide	bis(tri-n-butyltin)oxide results in decreased expression of ANG mRNA	26314263
C584509	C646 compound	C646 compound results in decreased expression of ANG mRNA	26191083
D019256	Cadmium Chloride	Acetylcysteine inhibits the reaction [Cadmium Chloride results in decreased secretion of ANG protein]	26138014
D019256	Cadmium Chloride	Cadmium Chloride results in decreased secretion of ANG protein	26138014
D002110	Caffeine	Caffeine results in decreased expression of ANG mRNA	11793227
D002121	Calcium Channel Blockers	Calcium Channel Blockers results in decreased susceptibility to ANG protein alternative form	9605596
C039671	ciglitazone	[ciglitazone binds to PPARG protein alternative form] which results in increased expression of ANG mRNA	16197558
D002995	Clofibric Acid	[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of ANG mRNA	17602206
C018021	cobaltous chloride	cobaltous chloride affects the expression of ANG mRNA	26314263
C018021	cobaltous chloride	cobaltous chloride results in increased expression of ANG mRNA	22202117
C018021	cobaltous chloride	cobaltous chloride results in increased secretion of ANG protein	16490744
C018021	cobaltous chloride	zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of ANG mRNA]	22202117
D003300	Copper	Copper affects the expression of ANG mRNA	25596488
D003300	Copper	Copper affects the localization of ANG protein	25596488
D019327	Copper Sulfate	Copper Sulfate results in decreased expression of ANG mRNA	19549813
D003471	Cuprizone	Cuprizone results in decreased expression of ANG mRNA	26577399
D016572	Cyclosporine	Cyclosporine affects the expression of ANG mRNA	20106945
D016572	Cyclosporine	Cyclosporine results in decreased expression of ANG mRNA	25562108
D016572	Cyclosporine	Cyclosporine results in increased expression of ANG mRNA	21632981\|2214713
C014347	decitabine	decitabine affects the expression of ANG mRNA	23300844
D002945	Cisplatin	Cisplatin affects the expression of ANG mRNA	23300844
D002945	Cisplatin	[Cisplatin co-treated with jinfukang] results in increased expression of ANG mRNA	27392435
D002945	Cisplatin	[Cisplatin co-treated with Paclitaxel] results in increased expression of ANG mRNA	20705681
D002945	Cisplatin	Cisplatin results in increased expression of ANG mRNA	19561079
D004008	Diclofenac	Diclofenac results in increased expression of ANG mRNA	26934552
D004041	Dietary Fats	Dietary Fats results in decreased expression of ANG mRNA	18042831
D004052	Diethylnitrosamine	Diethylnitrosamine results in decreased expression of ANG mRNA	24535843
D004052	Diethylnitrosamine	[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of ANG mRNA	17602206
D004052	Diethylnitrosamine	Diethylnitrosamine results in decreased expression of ANG mRNA	19638242
C015835	dimethyl-4-toluidine	dimethyl-4-toluidine results in decreased expression of ANG mRNA	27638505
D004318	Doxycycline	Doxycycline inhibits the reaction [Isoproterenol results in increased expression of ANG mRNA]	18089841
D004656	Enalapril	Enalapril results in decreased expression of ANG protein	3038326
D004726	Endosulfan	[Endosulfan co-treated with Tetrachlorodibenzodioxin] results in decreased expression of ANG mRNA	26159488
C118739	entinostat	entinostat results in increased expression of ANG mRNA	26272509
C118739	entinostat	"[NOG protein co-treated with entinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ANG mRNA"	27188386
D004997	Ethinyl Estradiol	Ethinyl Estradiol affects the expression of ANG mRNA	17555576
D005472	Fluorouracil	ANG protein affects the susceptibility to Fluorouracil	16217747
D005485	Flutamide	Flutamide results in decreased expression of ANG mRNA	24136188
C039281	furan	furan results in decreased expression of ANG mRNA	25539665\|2619464
D005665	Furosemide	Furosemide affects the expression of ANG mRNA	16526316
D005897	Glafenine	Glafenine results in decreased expression of ANG mRNA	24136188
C412815	GW 4064	GW 4064 results in increased expression of ANG mRNA	26655953
C492448	ICG 001	ICG 001 results in decreased expression of ANG mRNA	26191083
C016517	indole-3-carbinol	indole-3-carbinol results in decreased expression of ANG mRNA	16192472
D007545	Isoproterenol	Doxycycline inhibits the reaction [Isoproterenol results in increased expression of ANG mRNA]	18089841
D007545	Isoproterenol	Isoproterenol results in increased expression of ANG mRNA	18089841\|2000320
C544151	jinfukang	[Cisplatin co-treated with jinfukang] results in increased expression of ANG mRNA	27392435
C544151	jinfukang	jinfukang results in increased expression of ANG mRNA	27392435
C410337	K 7174	K 7174 results in decreased expression of ANG mRNA	24086573
C545385	Mequindox	Mequindox results in increased expression of ANG mRNA	20553828
C030957	methylmercury II	methylmercury II results in decreased expression of ANG mRNA	26314263
D008741	Methyl Methanesulfonate	Methyl Methanesulfonate results in increased expression of ANG mRNA	23649840
D037742	Nanotubes, Carbon	"Nanotubes, Carbon analog results in decreased expression of ANG mRNA"	25554681
C051752	nefazodone	nefazodone results in decreased expression of ANG mRNA	24136188
D009532	Nickel	Nickel results in decreased expression of ANG mRNA	24768652\|2558310
C012655	nimesulide	nimesulide results in decreased expression of ANG mRNA	24136188
C025589	ochratoxin A	ochratoxin A metabolite results in decreased expression of ANG mRNA	26314263
C025589	ochratoxin A	ochratoxin A results in decreased expression of ANG mRNA	26314263
C510784	ormosil	[ormosil binds to Polyethylene Glycols] which results in decreased expression of ANG mRNA	24888373
D010100	Oxygen	Oxygen deficiency results in increased expression of ANG mRNA	16490744
D010100	Oxygen	Oxygen deficiency results in increased secretion of ANG protein	16490744
D017239	Paclitaxel	[Cisplatin co-treated with Paclitaxel] results in increased expression of ANG mRNA	20705681
D000073878	Palm Oil	Palm Oil results in decreased expression of ANG mRNA	18042831
C496932	panobinostat	"[NOG protein co-treated with panobinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ANG mRNA"	27188386
C016030	pantogab	pantogab results in increased expression of ANG mRNA	17379144
C086401	pentabromodiphenyl ether	pentabromodiphenyl ether results in increased expression of ANG mRNA	26705709
D010634	Phenobarbital	Phenobarbital affects the expression of ANG mRNA	23091169
C006253	pirinixic acid	pirinixic acid results in decreased expression of ANG mRNA	20059764
C006253	pirinixic acid	pirinixic acid results in increased expression of ANG mRNA	17426115
C006253	pirinixic acid	PPARA protein promotes the reaction [pirinixic acid results in decreased expression of ANG mRNA]	20059764
D011092	Polyethylene Glycols	[ormosil binds to Polyethylene Glycols] which results in decreased expression of ANG mRNA	24888373
D011374	Progesterone	Progesterone results in increased expression of ANG mRNA	21795739
D011374	Progesterone	Progesterone affects the expression of ANG mRNA	17251523
C045950	propiconazole	propiconazole results in decreased expression of ANG mRNA	21278054
D011441	Propylthiouracil	Propylthiouracil results in decreased expression of ANG mRNA	24780913
D011794	Quercetin	Quercetin results in decreased expression of ANG mRNA	21632981
C502851	quinocetone	quinocetone results in increased expression of ANG mRNA	26296292
D020849	Raloxifene Hydrochloride	Raloxifene Hydrochloride results in increased expression of ANG mRNA	19429434
C541923	sandostatinLAR	sandostatinLAR results in decreased expression of ANG mRNA	17210224
D018038	Sodium Selenite	Sodium Selenite results in increased expression of ANG mRNA	18175754
D013749	Tetrachlorodibenzodioxin	[Endosulfan co-treated with Tetrachlorodibenzodioxin] results in decreased expression of ANG mRNA	26159488
D013749	Tetrachlorodibenzodioxin	[Estradiol co-treated with Tetrachlorodibenzodioxin] results in decreased expression of ANG mRNA	19619570
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin results in decreased expression of ANG mRNA	20106945
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin results in increased expression of ANG mRNA	19619570
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin affects the expression of ANG mRNA	12167310\|2157046
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to ANG gene]	28213091
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin results in decreased expression of ANG mRNA	28213091
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin results in decreased expression of ANG mRNA	16495355
D013853	Thioacetamide	Thioacetamide results in decreased expression of ANG mRNA	11793227
D013853	Thioacetamide	Thioacetamide results in decreased expression of ANG mRNA	23411599
D013864	Thioglycolates	Thioglycolates results in increased expression of ANG protein	9464241
C096900	thrombin receptor-activating peptide SFLLRNPNDKY	thrombin receptor-activating peptide SFLLRNPNDKY analog results in increased secretion of ANG protein	17303692
D014212	Tretinoin	Tretinoin results in increased expression of ANG mRNA	23830798
C011559	tributyltin	tributyltin results in decreased expression of ANG mRNA	26314263
C012589	trichostatin A	trichostatin A affects the expression of ANG mRNA	28542535
C012589	trichostatin A	trichostatin A results in increased expression of ANG mRNA	24935251
C057693	troglitazone	troglitazone results in decreased expression of ANG mRNA	25572481
D014520	Urethane	Urethane results in decreased expression of ANG mRNA	28818685
D014635	Valproic Acid	"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ANG mRNA"	27188386
D014635	Valproic Acid	Valproic Acid affects the expression of ANG mRNA	25979313
D014635	Valproic Acid	Valproic Acid results in decreased expression of ANG mRNA	29154799
D014635	Valproic Acid	Valproic Acid results in decreased methylation of ANG gene	29154799
D014635	Valproic Acid	Valproic Acid results in increased expression of ANG mRNA	19101580\|2317975
D014635	Valproic Acid	Valproic Acid results in increased expression of ANG mRNA	24896083
D000068756	Valsartan	Valsartan results in decreased expression of ANG mRNA	22768174
D024483	Vitamin K 3	Vitamin K 3 affects the expression of ANG mRNA	20044591
C111237	vorinostat	vorinostat results in increased expression of ANG mRNA	27188386
C016837	zinc chloride	zinc chloride inhibits the reaction [cobaltous chloride results in increased expression of ANG mRNA]	22202117

GO/Pathway

GO ID	GO Term	Qualifier	Evidence	PubMed
GO:0003677	DNA binding	-	IC	10649442
GO:0003779	actin binding	-	IDA	7679494 11782452
GO:0004519	endonuclease activity	-	IBA	21873635
GO:0004519	endonuclease activity	-	TAS	10103013
GO:0004540	ribonuclease activity	-	IBA	21873635
GO:0004540	ribonuclease activity	-	IDA	2424496 2730651
GO:0005102	signaling receptor binding	-	IDA	9122172
GO:0005507	copper ion binding	-	IDA	9245697
GO:0005515	protein binding	-	IPI	2742853 3470787 10413501 15737636 17991437 24457100 28777577
GO:0008201	heparin binding	-	IDA	10103013
GO:0019843	rRNA binding	-	TAS	2457905
GO:0042277	peptide binding	-	IDA	11782452
GO:0042803	protein homodimerization activity	-	IDA	25372031

GO ID	GO Term	Qualifier	Evidence	PubMed
GO:0001525	angiogenesis	-	IDA	8448182
GO:0001525	angiogenesis	-	IMP	2479414 17125737
GO:0001525	angiogenesis	-	TAS	16567967
GO:0001541	ovarian follicle development	-	NAS	12770725
GO:0001556	oocyte maturation	-	NAS	11438326
GO:0001666	response to hypoxia	-	IDA	10999833 15979542 16490744
GO:0001666	response to hypoxia	-	NAS	15776477
GO:0001890	placenta development	-	NAS	11984825
GO:0001938	positive regulation of endothelial cell proliferation	-	IDA	9122172 9707554
GO:0006651	diacylglycerol biosynthetic process	-	IDA	2457905
GO:0007154	cell communication	-	NAS	10103013
GO:0007202	activation of phospholipase C activity	-	IMP	2457905
GO:0009303	rRNA transcription	-	IMP	15735021
GO:0009725	response to hormone	-	IDA	10999833
GO:0016477	cell migration	-	IMP	17125737
GO:0017148	negative regulation of translation	-	IEA	-
GO:0030041	actin filament polymerization	-	ISS	-
GO:0032148	activation of protein kinase B activity	-	IMP	17125737
GO:0032431	activation of phospholipase A2 activity	-	IMP	2646638
GO:0034332	adherens junction organization	-	TAS	-
GO:0042327	positive regulation of phosphorylation	-	IDA	17125737
GO:0042592	homeostatic process	-	NAS	15166501
GO:0048662	negative regulation of smooth muscle cell proliferation	-	IDA	10103013
GO:0050714	positive regulation of protein secretion	-	IDA	2646638
GO:0050714	positive regulation of protein secretion	-	ISS	-
GO:0090501	RNA phosphodiester bond hydrolysis	-	IEA	-

GO ID	GO Term	Qualifier	Evidence	PubMed
GO:0005576	extracellular region	-	TAS	-
GO:0005605	basal lamina	-	IDA	15166501
GO:0005615	extracellular space	-	IDA	3663649 16461950 16490744
GO:0005634	nucleus	-	IDA	10649442 15735021 25372031
GO:0005730	nucleolus	-	ISS	-
GO:0030426	growth cone	-	ISS	-
GO:0031410	cytoplasmic vesicle	-	IEA	-
GO:0032311	angiogenin-PRI complex	-	IDA	3470787
GO:0032311	angiogenin-PRI complex	-	IPI	3470787
GO:0043025	neuronal cell body	-	ISS	-

KEGG ID	KEGG Term

Reactome ID	Reactome Term	Evidence
R-HSA-1500931	Cell-Cell communication	TAS
R-HSA-418990	Adherens junctions interactions	TAS
R-HSA-421270	Cell-cell junction organization	TAS
R-HSA-446728	Cell junction organization	TAS

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID	Title (Year)	Author	Journal
2178480	Angiotensin converting enzyme inhibitors reduce alcohol consumption: some possible mechanisms and important conditions for its therapeutic use. (1990 Feb)	Lingham T	Alcohol Clin Exp Res
19504428	First-trimester angiopoietin-2: relationships with maternal and placental characteristics. (2010 Jan)	Baschat AA	Am J Perinatol
27295092	Prenatal Nicotine Exposure Results in the Inhibition of Baroreflex Sensitivity Induced by Intravenous Injection Angiotensin II in the Adult Male Offspring Rats. (2017 Apr)	Yu F	Cardiovasc Toxicol
22494858	Ethnic/racial differences in circulating markers of angiogenesis and their association with cardiovascular risk factors and cardiovascular disease. (2013 Aug 20)	Bennett PC	Int J Cardiol
28537660	Relation between blood pressure variability and early renal damage in hypertensive patients. (2017 May)	Yin LH	Eur Rev Med Pharmacol Sci
20359117	[Expression and clinical significance of Ang-2 and MMP-7 in laryngeal carcinoma]. (2009 Nov)	Qin G	Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi
21479477	Angiopoietin-3 overexpression in tobacco smoke-induced mouse lung tumors and its relation to vitamin E intervention. (2008 Sep-Oct)	Zhang S	Mol Med Rep
23797033	Clinical perspective on oxidative stress in sporadic amyotrophic lateral sclerosis. (2013 Dec)	D'Amico E	Free Radic Biol Med
26003281	Staphylococcus aureus in former Portuguese colonies from Africa and the Far East: missing data to help fill the world map. (2015 Sep)	Conceicao T	Clin Microbiol Infect
16401677	Possible role for mast cell-derived cathepsin G in the adverse remodelling of stenotic aortic valves. (2006 Jun)	Helske S	Eur Heart J
15517881	Alteration of the vascular endothelial growth factor and angiopoietins-1 and -2 pathways in transitional cell carcinomas of the urinary bladder associated with tumor progression. (2004 Sep-Oct)	Quentin T	Anticancer Res
17258096	Lipopolysaccharide activates calcineurin in ventricular myocytes. (2007 Jan 30)	Suzuki J	J Am Coll Cardiol
21532855	Prevalence and risk factor of erosive esophagitis observed in Korean National Cancer Screening Program. (2011 May)	Kim BJ	J Korean Med Sci
23959951	Effects of nicotine on cardiovascular remodeling in a mouse model of systemic hypertension. (2013 Dec)	Colombo ES	Cardiovasc Toxicol
20409863	Central arterial aging and the epidemic of systolic hypertension and atherosclerosis. (2007 Sep-Oct)	Lakatta EG	J Am Soc Hypertens
11881123	The effects of candesartan on vascular responses to angiotensin II and norepinephrine in normal volunteers. (2001 Sep)	Tran D	J Renin Angiotensin Aldosterone Syst
25402718	Angiopoietins 1 and 2 in sputum supernatant of optimally treated asthmatics: the effect of smoking. (2015 Jan)	Petta V	Eur J Clin Invest
17577432	[Relationship between angiotensin converting enzyme gene and ischemic stroke]. (2007 Jun)	Li CM	Zhongguo Wei Zhong Bing Ji Jiu Yi Xue
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