Gene: OLFML1

283298
UNQ564
olfactomedin like 1
protein-coding
11p15.4
Ensembl:ENSG00000183801 Vega:OTTHUMG00000165527 UniprotKB:Q6UWY5
NC_000011.10
SNP Mapped
1   ANCO-SNPs
ND
0   
NA (AD)  NA (ND)   (Frontal_Cortex)
2.198e-1 (AD)  7.846e-1 (ND)

ANCO-SNPs

SNP ID Position Alleles Trait Variation Type
rs12805648chr11:7488335 (GRCh38.p7)A>Tnicotine dependenceSNV(Single Nucleotide Variation)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
PDE5A0.811
ATP2A30.789
GPX80.787
EBF10.765
OLFML2A0.754
FOXS10.753
LUM0.752
TBX180.748
ECM20.731
CHMP4C0.73

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
PTCHD1-0.416
GPR150-0.383
KHDC1-0.38
KIAA0319-0.378
ADPRHL1-0.373
AQP11-0.373
PTPRF-0.371
NME9-0.37
TENM3-0.369
DGAT2-0.368

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C0264861,2,5,6-dibenzanthracene"1,2,5,6-dibenzanthracene results in increased expression of OLFML1 mRNA"26377693
C0284741,4-bis(2-(3,5-dichloropyridyloxy))benzene"1,4-bis(2-(3,5-dichloropyridyloxy))benzene results in decreased expression of OLFML1 mRNA"21354444
C5850042-monochloropropanediol2-monochloropropanediol results in increased expression of OLFML1 mRNA28522335
C0230353,4,5,3',4'-pentachlorobiphenyl"3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of OLFML1 mRNA"23196670
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with mercuric bromide co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of OLFML1 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of OLFML1 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of OLFML1 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with mercuric bromide co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of OLFML1 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of OLFML1 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of OLFML1 mRNA"27188386
D016604Aflatoxin B1Aflatoxin B1 results in increased methylation of OLFML1 gene27153756
D016604Aflatoxin B1Aflatoxin B1 results in decreased expression of OLFML1 mRNA19770486
D016604Aflatoxin B1Aflatoxin B1 results in increased expression of OLFML1 mRNA23630614
D000517alpha-Chlorohydrinalpha-Chlorohydrin results in increased expression of OLFML1 mRNA28522335
D001104ArbutinArbutin results in decreased expression of OLFML1 mRNA17103032
D001151ArsenicArsenic affects the methylation of OLFML1 gene25304211
D001280AtrazineAtrazine results in increased expression of OLFML1 mRNA25929836
D019324beta-Naphthoflavone[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of OLFML1 mRNA18164116
D001564Benzo(a)pyreneBenzo(a)pyrene results in decreased expression of OLFML1 mRNA21632981
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased mutagenesis of OLFML1 gene25435355
D004958Estradiol[Estradiol co-treated with Progesterone] results in decreased expression of OLFML1 mRNA20660070
C006780bisphenol A[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of OLFML1 mRNA28628672
C006780bisphenol Abisphenol A affects the expression of OLFML1 mRNA25181051
C000611646bisphenol F[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of OLFML1 mRNA28628672
D002251Carbon TetrachlorideCarbon Tetrachloride affects the expression of OLFML1 mRNA17484886
D002251Carbon TetrachlorideCarbon Tetrachloride results in decreased expression of OLFML1 mRNA27339419
C018021cobaltous chloridecobaltous chloride results in decreased expression of OLFML1 mRNA24612858
D016572CyclosporineCyclosporine results in decreased expression of OLFML1 mRNA25562108
D016572CyclosporineCyclosporine results in decreased expression of OLFML1 mRNA19770486
D003907Dexamethasone[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of OLFML1 mRNA28628672
D003907Dexamethasone[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of OLFML1 mRNA28628672
D003999Dichloroacetic AcidDichloroacetic Acid results in decreased expression of OLFML1 mRNA28962523
D004052Diethylnitrosamine[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of OLFML1 mRNA18164116
D002117CalcitriolCalcitriol results in decreased expression of OLFML1 mRNA26485663
D0151279,10-Dimethyl-1,2-benzanthracene"9,10-Dimethyl-1,2-benzanthracene results in decreased expression of OLFML1 mRNA"22485181
D004237DiuronDiuron results in decreased expression of OLFML1 mRNA25152437
C118739entinostatentinostat results in increased expression of OLFML1 mRNA27188386
D004397FonofosFonofos results in increased methylation of OLFML1 promoter22847954
C039281furanfuran results in decreased expression of OLFML1 mRNA24183702
C039281furanfuran results in increased expression of OLFML1 mRNA27387713
C412815GW 4064GW 4064 results in increased expression of OLFML1 mRNA26655953
D017313FenretinideFenretinide results in decreased expression of OLFML1 mRNA28973697
D007213Indomethacin[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of OLFML1 mRNA28628672
D007213Indomethacin[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of OLFML1 mRNA28628672
D0150561-Methyl-3-isobutylxanthine[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of OLFML1 mRNA28628672
D0150561-Methyl-3-isobutylxanthine[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of OLFML1 mRNA28628672
C011890kojic acidkojic acid results in decreased expression of OLFML1 mRNA16595896
C042720mercuric bromidemercuric bromide results in increased expression of OLFML1 mRNA26272509
C042720mercuric bromide"[NOG protein co-treated with mercuric bromide co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of OLFML1 mRNA"27188386
D008627Mercuric ChlorideMercuric Chloride results in decreased expression of OLFML1 mRNA16507785
D008741Methyl MethanesulfonateMethyl Methanesulfonate results in decreased expression of OLFML1 mRNA26011545
D037742Nanotubes, Carbon"Nanotubes, Carbon analog results in decreased expression of OLFML1 mRNA"25554681|2562005
D037742Nanotubes, Carbon"Nanotubes, Carbon results in decreased expression of OLFML1 mRNA"25554681|2562005
D009532NickelNickel results in decreased expression of OLFML1 mRNA25583101
C572573N-nitroso-tris-chloroethylurea[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of OLFML1 mRNA27935865
C572573N-nitroso-tris-chloroethylurea[N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of OLFML1 mRNA27935865
C016030pantogabpantogab results in decreased expression of OLFML1 mRNA17379144
D010278ParathionParathion results in increased methylation of OLFML1 promoter22847954
D010634PhenobarbitalPhenobarbital results in increased expression of OLFML1 mRNA19270015
D010662Phenylmercuric Acetate"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of OLFML1 mRNA"27188386
D010662Phenylmercuric AcetatePhenylmercuric Acetate results in increased expression of OLFML1 mRNA26272509
C060836pioglitazone[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of OLFML1 mRNA27935865
C006253pirinixic acid[pirinixic acid co-treated with PPARA] results in decreased expression of OLFML1 mRNA20813756
C006253pirinixic acidpirinixic acid results in decreased expression of OLFML1 mRNA20813756|2381119
D011374Progesterone[Estradiol co-treated with Progesterone] results in decreased expression of OLFML1 mRNA20660070
C045950propiconazolepropiconazole results in decreased expression of OLFML1 mRNA21278054
D011441PropylthiouracilPropylthiouracil results in decreased expression of OLFML1 mRNA24780913
D011794QuercetinQuercetin results in decreased expression of OLFML1 mRNA21632981
D012822Silicon DioxideSilicon Dioxide analog results in increased expression of OLFML1 mRNA25895662
D012822Silicon DioxideSilicon Dioxide results in decreased expression of OLFML1 mRNA23221170
D053260SootSoot results in decreased expression of OLFML1 mRNA26551751
C012568terbufosterbufos results in increased methylation of OLFML1 promoter22847954
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of OLFML1 mRNA21570461
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of OLFML1 mRNA19770486
D014635Valproic Acid"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of OLFML1 mRNA"27188386
D014635Valproic AcidValproic Acid affects the expression of OLFML1 mRNA25979313
D014635Valproic AcidValproic Acid results in increased expression of OLFML1 mRNA23179753|2627250
D001335Vehicle EmissionsVehicle Emissions affects the methylation of OLFML1 gene25560391
C581157XL147[N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of OLFML1 mRNA27935865

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO ID GO Term Qualifier Evidence PubMed
GO ID GO Term Qualifier Evidence PubMed
GO:0005576extracellular region-IEA-  
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence

Interactions (STRING v10.5, Interaction Score >= 0.400)

There is no Interaction data for this gene.

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal