Gene: B4GALNT3

283358
-
beta-1,4-N-acetyl-galactosaminyltransferase 3
protein-coding
12p13.33
Ensembl:ENSG00000139044 MIM:612220 Vega:OTTHUMG00000129283 UniprotKB:Q6L9W6
NC_000012.12
SNP Mapped
1   ANCO-SNPs
AD
0   
NA (AD)  NA (ND)   (Frontal_Cortex)
5.435e-1 (AD)  4.948e-1 (ND)

ANCO-SNPs

SNP ID Position Alleles Trait Variation Type
rs2075033chr12:535171 (GRCh38.p7)G>Aalcohol dependenceSNV(Single Nucleotide Variation)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
STK11IP0.881
SRRM30.867
PRSS530.867
TMEM63C0.862
SNAPC40.861
DDX510.861
ZFR20.859
TRIM110.852
HCN30.85
ZFYVE280.849

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
MBNL3-0.485
ASB4-0.481
TSPAN12-0.477
YES1-0.454
SLC40A1-0.452
COPZ2-0.434
TRDN-0.426
NXT2-0.423
ANTXR1-0.422
LRAT-0.42

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C5172321,2-dibromo-4-(1,2-dibromoethyl)cyclohexane"1,2-dibromo-4-(1,2-dibromoethyl)cyclohexane results in increased expression of B4GALNT3 mRNA"24375616
D016604Aflatoxin B1Aflatoxin B1 results in decreased methylation of B4GALNT3 gene27153756
D0151248-Bromo Cyclic Adenosine Monophosphate8-Bromo Cyclic Adenosine Monophosphate results in increased expression of B4GALNT3 mRNA22079614
D003976DiazinonDiazinon results in increased methylation of B4GALNT3 gene22964155
C000944dicrotophosdicrotophos results in increased expression of B4GALNT3 mRNA28302478
D004026DieldrinDieldrin results in increased expression of B4GALNT3 mRNA20438755
D004041Dietary FatsDietary Fats results in decreased expression of B4GALNT3 mRNA28031460
D017313FenretinideFenretinide results in increased expression of B4GALNT3 mRNA28973697
C561695(+)-JQ1 compound(+)-JQ1 compound results in decreased expression of B4GALNT3 mRNA26752646
D007854LeadLead results in increased expression of B4GALNT3 mRNA19921347
D0156551-Methyl-4-phenylpyridinium1-Methyl-4-phenylpyridinium results in increased expression of B4GALNT3 mRNA24810058
C572573N-nitroso-tris-chloroethylurea[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of B4GALNT3 mRNA27935865
C060836pioglitazone[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of B4GALNT3 mRNA27935865
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of B4GALNT3 mRNA24680724

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0008376acetylgalactosaminyltransferase activity-IDA12966086  
GO:0033842N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO ID GO Term Qualifier Evidence PubMed
GO:0016021integral component of membrane-IEA-  
GO:0032580Golgi cisterna membrane-IEA-  
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal