Gene: C12orf40

283461
HEL-206|HEL-S-94
chromosome 12 open reading frame 40
protein-coding
12q12
Ensembl:ENSG00000180116 Vega:OTTHUMG00000133567 UniprotKB:Q86WS4
NC_000012.12
SNP Mapped
0   ANCO-SNPs
ND
0   
NA (AD)  NA (ND)   (Frontal_Cortex)
4.427e-1 (AD)  1.863e-2 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
SPO110.529
PCAT40.519
MMP130.514
ZIM30.5
FGF190.485
TAS2R600.48
HMGA20.479
AADACL30.474
OR14J10.47
MMP120.469

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
MCF2-0.313
SNAP25-AS1-0.307
DEPTOR-0.307
ARHGEF28-0.304
TMEFF2-0.303
REPS2-0.301
MFSD6-0.298
MAGEC3-0.297
SAMD12-0.293
EFCAB5-0.293

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C0272962-amino-4-chlorophenolC12ORF40 gene SNP affects the susceptibility to 2-amino-4-chlorophenol25622337
C006780bisphenol Abisphenol A results in decreased expression of C12ORF40 mRNA25181051

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0005515protein binding-IPI25416956  
GO ID GO Term Qualifier Evidence PubMed
GO ID GO Term Qualifier Evidence PubMed
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence

Interactions (STRING v10.5, Interaction Score >= 0.400)

There is no Interaction data for this gene.

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal