Gene: C1orf167

284498
-
chromosome 1 open reading frame 167
protein-coding
1p36.22
Ensembl:ENSG00000215910 Vega:OTTHUMG00000002228 UniprotKB:Q5SNV9
NC_000001.11
SNP Mapped
1   ANCO-SNPs
ND
0   
NA (AD)  NA (ND)   (Frontal_Cortex)
NA (AD)  NA (ND)

ANCO-SNPs

SNP ID Position Alleles Trait Variation Type
rs10864540chr1:11778042 (GRCh38.p7)A>Gnicotine dependenceSNV(Single Nucleotide Variation)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
IL17A0.601
CENPCP10.58
LALBA0.539
OR11G20.537
IL31RA0.534
NLRP100.532
DSG40.53
HES20.528
LINC004300.523
OR8H10.522

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
OMG-0.294
OPRK1-0.283
HRH3-0.258
TUBA3D-0.257
KCNH6-0.256
MLLT3-0.248
PURG-0.245
CXXC4-0.244
SFTPC-0.244
HSD17B1-0.241

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C006780bisphenol Abisphenol A results in increased expression of C1ORF167 mRNA29275510
C006780bisphenol A[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of C1ORF167 mRNA28628672
C018475butyraldehydebutyraldehyde results in increased expression of C1ORF167 mRNA26079696
D003907Dexamethasone[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of C1ORF167 mRNA28628672
D007213Indomethacin[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of C1ORF167 mRNA28628672
D0150561-Methyl-3-isobutylxanthine[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of C1ORF167 mRNA28628672
D012822Silicon DioxideSilicon Dioxide analog results in decreased expression of C1ORF167 mRNA25895662
C016805tris(1,3-dichloro-2-propyl)phosphate"tris(1,3-dichloro-2-propyl)phosphate results in decreased expression of C1ORF167 mRNA"26179874

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO ID GO Term Qualifier Evidence PubMed
GO ID GO Term Qualifier Evidence PubMed
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal