Gene: C16orf72

29035
PRO0149
chromosome 16 open reading frame 72
protein-coding
16p13.2
Ensembl:ENSG00000182831 Vega:OTTHUMG00000178147 UniprotKB:Q14CZ0
NC_000016.10
SNP Mapped
1   ANCO-SNPs
AD
0   
NA (AD)  NA (ND)   (Frontal_Cortex)
1.122e-1 (AD)  2.194e-1 (ND)

ANCO-SNPs

SNP ID Position Alleles Trait Variation Type
rs3743832chr16:9120023 (GRCh38.p7)A>Calcohol dependenceSNV(Single Nucleotide Variation)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
CCT40.919
DNAJA10.906
SIAH20.905
HSPA40.903
NUFIP20.897
DNAJB60.895
CCT50.894
PPID0.889
ELAVL10.886
UBE2D30.883

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
OR4F5-0.609
OR4F29-0.564
COX4I2-0.288
KLRF1-0.279
KLRB1-0.276
P2RY14-0.274
FCRL1-0.264
TNFRSF13B-0.257
AKR1B15-0.255
ANPEP-0.251

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C5112952,2',4,4'-tetrabromodiphenyl ether"2,2',4,4'-tetrabromodiphenyl ether analog results in increased expression of C16ORF72 mRNA"19095052
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with methylmercuric chloride co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of C16ORF72 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with methylmercuric chloride co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of C16ORF72 mRNA"27188386
D000082AcetaminophenAcetaminophen results in increased expression of C16ORF72 mRNA21420995|2906747
D016604Aflatoxin B1Aflatoxin B1 results in decreased methylation of C16ORF72 gene27153756
D018501Antirheumatic AgentsAntirheumatic Agents results in increased expression of C16ORF72 mRNA24449571
D017638Asbestos, Crocidolite"Asbestos, Crocidolite results in increased expression of C16ORF72 mRNA"18687144
D004958EstradiolEstradiol results in increased expression of C16ORF72 mRNA23019147
C006780bisphenol Abisphenol A results in increased expression of C16ORF72 mRNA25181051
D016572CyclosporineCyclosporine results in increased expression of C16ORF72 mRNA20106945|2556210
D004365Drugs, Chinese Herbal"Drugs, Chinese Herbal results in increased expression of C16ORF72 mRNA"23811387
C045651epigallocatechin gallate[potassium chromate(VI) co-treated with epigallocatechin gallate] results in increased expression of C16ORF72 mRNA22079256
C410337K 7174K 7174 results in increased expression of C16ORF72 mRNA24086573
C004925methylmercuric chloridemethylmercuric chloride results in increased expression of C16ORF72 mRNA26272509
C004925methylmercuric chloride"[NOG protein co-treated with methylmercuric chloride co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of C16ORF72 mRNA"27188386
D009285NaphthoquinonesNaphthoquinones results in increased expression of C16ORF72 mRNA23811387
D009532NickelNickel results in increased expression of C16ORF72 mRNA25583101
C568608PCI 5002[PCI 5002 co-treated with Zinc] results in increased expression of C16ORF72 mRNA18593933
C086401pentabromodiphenyl etherpentabromodiphenyl ether analog results in increased expression of C16ORF72 mRNA19095052
D010426Pentosan Sulfuric PolyesterPentosan Sulfuric Polyester results in increased expression of C16ORF72 mRNA28973697
C027373potassium chromate(VI)[potassium chromate(VI) co-treated with epigallocatechin gallate] results in increased expression of C16ORF72 mRNA22079256
C027373potassium chromate(VI)potassium chromate(VI) results in increased expression of C16ORF72 mRNA22079256
D012834SilverSilver results in increased expression of C16ORF72 mRNA26014281
D014028Tobacco Smoke PollutionTobacco Smoke Pollution results in increased expression of C16ORF72 mRNA28065790
C483909torcetrapibtorcetrapib results in increased expression of C16ORF72 mRNA23228038
C057693troglitazonetroglitazone results in decreased expression of C16ORF72 mRNA28973697
D014520UrethaneUrethane results in increased expression of C16ORF72 mRNA28818685
D014635Valproic AcidValproic Acid affects the expression of C16ORF72 mRNA25979313
D014635Valproic AcidValproic Acid results in decreased expression of C16ORF72 mRNA27188386
D014635Valproic AcidValproic Acid results in decreased methylation of C16ORF72 gene29154799
D015032Zinc[PCI 5002 co-treated with Zinc] results in increased expression of C16ORF72 mRNA18593933

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0005515protein binding-IPI25416956  
GO ID GO Term Qualifier Evidence PubMed
GO ID GO Term Qualifier Evidence PubMed
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence

Interactions (STRING v10.5, Interaction Score >= 0.400)

There is no Interaction data for this gene.

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal