Gene: STXBP6

29091
HSPC156|amisyn
syntaxin binding protein 6
protein-coding
14q12
Ensembl:ENSG00000168952 MIM:607958 Vega:OTTHUMG00000140186 UniprotKB:Q8NFX7
NC_000014.9
PubMed
ND
2   
NA (AD)  NA (ND)   (Frontal_Cortex)
1.674e-1 (AD)  8.178e-1 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
TMEM650.868
BTBD30.855
PBX10.851
GRIA40.841
PIP5K1B0.839
PPP4R40.836
MCFD20.833
SGTB0.832
CBLN40.83
C1orf210.828

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
OR4F5-0.519
OR4F29-0.48
CSAG1-0.396
SPINK8-0.384
SH2D1A-0.358
GNG8-0.35
TGFB3-0.349
SH2D2A-0.343
GJA4-0.337
PPBP-0.335

Drugs/Compounds

    There is no DrugBank record for this gene !

    There is no CTD record for this GENE !

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO ID GO Term Qualifier Evidence PubMed
GO ID GO Term Qualifier Evidence PubMed
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
28198450Identification of Methylation-Driven, Differentially Expressed STXBP6 as a Novel Biomarker in Lung Adenocarcinoma. (2017 Feb 15)Lenka GSci Rep
23897225Skin gene expression correlates of severity of interstitial lung disease in systemic sclerosis. (2013 Nov)Assassi SArthritis Rheum