Gene: GSK3B

2932
-
glycogen synthase kinase 3 beta
protein-coding
3q13.33
Ensembl:ENSG00000082701 MIM:605004 Vega:OTTHUMG00000133765 UniprotKB:P49841
NG_012922.1
PubMed
ND|AD
5   
NA (AD)  NA (ND)   (Frontal_Cortex)
9.662e-1 (AD)  9.979e-1 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
ATP6V1A0.975
ATP6V1C10.974
TRIM370.973
RNMT0.972
KIF3A0.972
UBE2K0.972
SYNJ10.971
ZYG11B0.971
WDR470.97
MTMR90.969

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
OR4F5-0.532
CSAG1-0.489
OR4F29-0.489
HEY2-0.464
RHOD-0.447
RAB13-0.443
MYL3-0.44
ROM1-0.426
COPZ2-0.426
CNN2-0.425

Drugs/Compounds

ID Drug Name Drug Type CAS Num Status Role
DB01356LithiumSmall Molecule7439-93-2ApprovedTarget
DB017723-[3-(2,3-Dihydroxy-Propylamino)-Phenyl]-4-(5-Fluoro-1-Methyl-1h-Indol-3-Yl)-Pyrrole-2,5-DioneSmall MoleculeExperimentalTarget
DB01793SB-409513Small MoleculeExperimentalTarget
DB01950N-(4-Methoxybenzyl)-N'-(5-Nitro-1,3-Thiazol-2-Yl)UreaSmall MoleculeExperimentalTarget
DB02010StaurosporineSmall Molecule62996-74-1ExperimentalTarget
DB02052Indirubin-3'-MonoximeSmall MoleculeExperimentalTarget
DB03444(3e)-6'-Bromo-2,3'-Biindole-2',3(1h,1'h)-Dione 3-OximeSmall MoleculeExperimentalTarget
DB04014AlsterpaulloneSmall MoleculeExperimentalTarget
DB04395Phosphoaminophosphonic Acid-Adenylate EsterSmall MoleculeExperimentalTarget
DB070142-(1,3-benzodioxol-5-yl)-5-[(3-fluoro-4-methoxybenzyl)sulfanyl]-1,3,4-oxadiazoleSmall MoleculeExperimentalTarget
DB070585-[1-(4-methoxyphenyl)-1H-benzimidazol-6-yl]-1,3,4-oxadiazole-2(3H)-thioneSmall MoleculeExperimentalTarget
DB07149(7S)-2-(2-aminopyrimidin-4-yl)-7-(2-fluoroethyl)-1,5,6,7-tetrahydro-4H-pyrrolo[3,2-c]pyridin-4-oneSmall MoleculeExperimentalTarget
DB07584N-[2-(5-methyl-4H-1,2,4-triazol-3-yl)phenyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amineSmall MoleculeExperimentalTarget
DB075855-(5-chloro-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridineSmall MoleculeExperimentalTarget
DB076763-({[(3S)-3,4-dihydroxybutyl]oxy}amino)-1H,2'H-2,3'-biindol-2'-oneSmall MoleculeExperimentalTarget
DB07812N-[(1S)-2-amino-1-phenylethyl]-5-(1H-pyrrolo[2,3-b]pyridin-4-yl)thiophene-2-carboxamideSmall MoleculeExperimentalTarget
DB078594-(4-CHLOROPHENYL)-4-[4-(1H-PYRAZOL-4-YL)PHENYL]PIPERIDINESmall MoleculeExperimentalTarget
DB07947ISOQUINOLINE-5-SULFONIC ACID (2-(2-(4-CHLOROBENZYLOXY)ETHYLAMINO)ETHYL)AMIDESmall MoleculeExperimentalTarget
DB08073(2S)-1-(1H-INDOL-3-YL)-3-{[5-(3-METHYL-1H-INDAZOL-5-YL)PYRIDIN-3-YL]OXY}PROPAN-2-AMINESmall MoleculeExperimentalTarget
DB12129TideglusibSmall Molecule865854-05-3Investigational|WithdrawnTarget
ID Drug Name Action PubMed
C0256031,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid"1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid inhibits the reaction [Rotenone results in decreased phosphorylation of GSK3B protein]"25433145
C0487921,2-diacetylbenzene"1,2-diacetylbenzene affects the phosphorylation of and results in increased activity of GSK3B protein"28734998
C0487921,2-diacetylbenzene"2-thio(3-iodobenzyl)-5-(1-pyridyl)-(1,3,4)oxadiazole inhibits the reaction [1,2-diacetylbenzene affects the phosphorylation of and results in increased activity of GSK3B protein]"28734998
C0487921,2-diacetylbenzene"1,2-diacetylbenzene affects the phosphorylation of and results in increased activity of GSK3B protein"28734998
C5172321,2-dibromo-4-(1,2-dibromoethyl)cyclohexane"1,2-dibromo-4-(1,2-dibromoethyl)cyclohexane results in decreased expression of GSK3B mRNA"23958786
C5326571,3-dihydro-1-(1-((4-(6-phenyl-1H-imidazo(4,5-g)quinoxalin-7-yl)phenyl)methyl)-4-piperidinyl)-2H-benzimidazol-2-one"1,3-dihydro-1-(1-((4-(6-phenyl-1H-imidazo(4,5-g)quinoxalin-7-yl)phenyl)methyl)-4-piperidinyl)-2H-benzimidazol-2-one analog inhibits the reaction [Asbestos, Serpentine results in increased phosphorylation of GSK3B protein]"26685284
C5326571,3-dihydro-1-(1-((4-(6-phenyl-1H-imidazo(4,5-g)quinoxalin-7-yl)phenyl)methyl)-4-piperidinyl)-2H-benzimidazol-2-one"1,3-dihydro-1-(1-((4-(6-phenyl-1H-imidazo(4,5-g)quinoxalin-7-yl)phenyl)methyl)-4-piperidinyl)-2H-benzimidazol-2-one inhibits the reaction [Bibenzyls inhibits the reaction [Rotenone results in decreased phosphorylation of GSK3B protein]]"28245986
C5326571,3-dihydro-1-(1-((4-(6-phenyl-1H-imidazo(4,5-g)quinoxalin-7-yl)phenyl)methyl)-4-piperidinyl)-2H-benzimidazol-2-one"1,3-dihydro-1-(1-((4-(6-phenyl-1H-imidazo(4,5-g)quinoxalin-7-yl)phenyl)methyl)-4-piperidinyl)-2H-benzimidazol-2-one inhibits the reaction [Bibenzyls inhibits the reaction [Rotenone results in decreased phosphorylation of GSK3B protein]]"28245986
C0284741,4-bis(2-(3,5-dichloropyridyloxy))benzene"1,4-bis(2-(3,5-dichloropyridyloxy))benzene results in decreased expression of GSK3B protein"21705713
C0952841H-(1,2,4)oxadiazolo(4,3-a)quinoxalin-1-one"1H-(1,2,4)oxadiazolo(4,3-a)quinoxalin-1-one inhibits the reaction [resveratrol results in increased activity of GSK3B protein]"19135050
C5321622-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine"2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine results in decreased phosphorylation of GSK3B protein"19584227|2280195
C5321622-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine"[ERBB2 gene mutant form results in increased susceptibility to 2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine] which results in decreased phosphorylation of GSK3B protein"20453058
C5321622-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine"[OGT mutant form results in increased susceptibility to 2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine] which results in decreased phosphorylation of GSK3B protein"23029544
C5321622-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine"[PTEN gene mutant form results in increased susceptibility to 2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine] which results in decreased phosphorylation of GSK3B protein"20453058
C4776942,2',4,4',5-brominated diphenyl ether"2,2',4,4',5-brominated diphenyl ether results in decreased phosphorylation of and results in increased activity of GSK3B protein"24218147
C0939732-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [resveratrol results in increased phosphorylation of and results in increased activity of GSK3B protein]20696143
C0939732-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one promotes the reaction [resveratrol results in decreased phosphorylation of and results in decreased activity of GSK3B protein]20696143
C0939732-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [manganese chloride results in decreased phosphorylation of GSK3B protein]20937724
C0939732-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [manganese chloride results in increased activity of GSK3B protein]20937724
C5054562-((2-piperidin-1-ylethyl)thio)quinazolin-4(3H)-one2-((2-piperidin-1-ylethyl)thio)quinazolin-4(3H)-one inhibits the reaction [Isoproterenol results in decreased phosphorylation of GSK3B protein]18806606
C5054562-((2-piperidin-1-ylethyl)thio)quinazolin-4(3H)-one2-((2-piperidin-1-ylethyl)thio)quinazolin-4(3H)-one inhibits the reaction [Isoproterenol results in increased phosphorylation of GSK3B protein]16716347
C5054562-((2-piperidin-1-ylethyl)thio)quinazolin-4(3H)-one2-((2-piperidin-1-ylethyl)thio)quinazolin-4(3H)-one promotes the reaction [Isoproterenol results in increased phosphorylation of GSK3B protein]15951400
C5054562-((2-piperidin-1-ylethyl)thio)quinazolin-4(3H)-one2-((2-piperidin-1-ylethyl)thio)quinazolin-4(3H)-one results in increased phosphorylation of GSK3B protein15951400
C0930262,3,5,4'-tetrahydroxystilbene 2-O-glucopyranoside"2,3,5,4'-tetrahydroxystilbene 2-O-glucopyranoside inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased phosphorylation of GSK3B protein]"23911879
C0140242,4,5,2',4',5'-hexachlorobiphenyl"2,4,5,2',4',5'-hexachlorobiphenyl results in decreased phosphorylation of GSK3B protein"20394812
C0859112-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Neomycin results in increased phosphorylation of GSK3B protein]15800129
C0859112-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [DEFA1 protein results in increased phosphorylation of GSK3B protein]19814765
C0859112-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [DEFA2 protein results in increased phosphorylation of GSK3B protein]19814765
C0859112-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [IGF1 protein promotes the reaction [1-Methyl-4-phenylpyridinium results in increased phosphorylation of GSK3B protein]]20064577
C0859112-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Polychlorinated Biphenyls analog results in decreased expression of GSK3B protein]24361488
C0859112-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [resveratrol results in increased phosphorylation of and results in increased activity of GSK3B protein]20696143
C0859112-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [resveratrol results in increased phosphorylation of GSK3B protein]14750165
C0859112-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Zinc results in increased phosphorylation of GSK3B protein]17513037
C0859112-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one promotes the reaction [resveratrol results in decreased phosphorylation of and results in decreased activity of GSK3B protein]20696143
C0859112-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in decreased phosphorylation of and results in increased activity of GSK3B protein15942663|1966122
C0859112-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in decreased phosphorylation of GSK3B protein21821001|2204644
C0859112-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one[2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in decreased phosphorylation of GSK3B protein] which results in decreased susceptibility to Bleomycin19429264
C0859112-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in increased activity of GSK3B protein15753396
C0859112-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-oneGSK3B mutant form inhibits the reaction [2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in increased expression of LGALS3 protein]21821001
C0859112-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-oneGSK3B results in decreased susceptibility to 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one21821001
C0859112-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-oneTamoxifen promotes the reaction [2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in decreased phosphorylation of GSK3B protein]22046442
C0859112-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [EPO protein results in increased phosphorylation of and results in increased activity of GSK3B protein]17928571
C0859112-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Estradiol results in increased phosphorylation of GSK3B protein]15845746
C0859112-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Quercetin inhibits the reaction [Okadaic Acid affects the phosphorylation of GSK3B protein]]27050422
C0859112-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [resveratrol results in increased phosphorylation of and results in decreased activity of GSK3B protein]20542495
C0859112-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one"2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Toluene 2,4-Diisocyanate results in increased phosphorylation of GSK3B protein]"26089345
C0859112-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in decreased phosphorylation of GSK3B protein16179367
C0859112-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-oneGSK3B mRNA affects the susceptibility to 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one21832246
C0859112-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased phosphorylation of GSK3B protein]20064577
C0859112-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [5-aminoisoquinolinone inhibits the reaction [Hydrogen Peroxide results in decreased phosphorylation of GSK3B protein]]23352507
C0859112-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Ecdysterone inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased phosphorylation of and results in decreased activity of GSK3B protein]]26048653
C0859112-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [EPO results in increased phosphorylation of GSK3B protein]17952604
C0859112-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [gypenoside analog results in increased phosphorylation of GSK3B protein]24726523
C0859112-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Phytoestrogens results in increased phosphorylation of GSK3B protein]24726523
C0859112-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Tetrachlorodibenzodioxin results in increased phosphorylation of GSK3B protein]24231000
C0235142,6-dinitrotoluene"2,6-dinitrotoluene affects the expression of GSK3B mRNA"21346803
C07699627-hydroxycholesterol27-hydroxycholesterol results in decreased expression of GSK3B protein20157255
C0292162-amino-3-methylimidazo(4,5-f)quinoline"[chlorophyllin affects the reaction [2-amino-3-methylimidazo(4,5-f)quinoline results in increased mutagenesis of CTNNB1 gene]] inhibits the reaction [GSK3B protein results in increased phosphorylation of and results in increased ubiquitination of CTNNB1 protein]"12628520
C4958182-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [IGF1 protein results in increased phosphorylation of GSK3B protein]20053781
C4958182-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [INS protein results in increased phosphorylation of GSK3B protein]20053781
C0299552-nitrotoluene2-nitrotoluene affects the expression of GSK3B mRNA16460773
C5295482-thio(3-iodobenzyl)-5-(1-pyridyl)-(1,3,4)oxadiazole"2-thio(3-iodobenzyl)-5-(1-pyridyl)-(1,3,4)oxadiazole inhibits the reaction [1,2-diacetylbenzene affects the phosphorylation of and results in increased activity of GSK3B protein]"28734998
C5295482-thio(3-iodobenzyl)-5-(1-pyridyl)-(1,3,4)oxadiazole"2-thio(3-iodobenzyl)-5-(1-pyridyl)-(1,3,4)oxadiazole results in decreased activity of GSK3B protein"28734998
C5295482-thio(3-iodobenzyl)-5-(1-pyridyl)-(1,3,4)oxadiazole"2-thio(3-iodobenzyl)-5-(1-pyridyl)-(1,3,4)oxadiazole results in decreased activity of GSK3B protein"23085120
C4175203-(3-chloro-4-hydroxyphenylamino)-4-(4-nitrophenyl)-1H-pyrrole-2,5-dione"3-(3-chloro-4-hydroxyphenylamino)-4-(4-nitrophenyl)-1H-pyrrole-2,5-dione results in decreased activity of GSK3B protein"19486905
C4175203-(3-chloro-4-hydroxyphenylamino)-4-(4-nitrophenyl)-1H-pyrrole-2,5-dione"[3-(3-chloro-4-hydroxyphenylamino)-4-(4-nitrophenyl)-1H-pyrrole-2,5-dione results in decreased activity of GSK3B protein] inhibits the reaction [Sirolimus results in decreased expression of CCND1 protein]"15753396
C4175203-(3-chloro-4-hydroxyphenylamino)-4-(4-nitrophenyl)-1H-pyrrole-2,5-dione"3-(3-chloro-4-hydroxyphenylamino)-4-(4-nitrophenyl)-1H-pyrrole-2,5-dione results in decreased activity of GSK3B protein"19159680
C4175203-(3-chloro-4-hydroxyphenylamino)-4-(4-nitrophenyl)-1H-pyrrole-2,5-dione"[3-(3-chloro-4-hydroxyphenylamino)-4-(4-nitrophenyl)-1H-pyrrole-2,5-dione results in decreased activity of GSK3B protein] which results in increased expression of CTNNB1 protein"19159680
C4175203-(3-chloro-4-hydroxyphenylamino)-4-(4-nitrophenyl)-1H-pyrrole-2,5-dione"3-(3-chloro-4-hydroxyphenylamino)-4-(4-nitrophenyl)-1H-pyrrole-2,5-dione results in decreased activity of GSK3B protein"15475000|1594266
C0163923,3'-diindolylmethane"3,3'-diindolylmethane results in decreased phosphorylation of GSK3B protein"22290291
C4972863,4',5-trimethoxystilbene"3,4',5-trimethoxystilbene results in decreased phosphorylation of and results in increased expression of GSK3B protein"23921149
C5464123-((4-chlorobenzyl)oxy)-N-((1S)-1-phenylethyl)-2-thiophenecarboxamide3-((4-chlorobenzyl)oxy)-N-((1S)-1-phenylethyl)-2-thiophenecarboxamide results in increased phosphorylation of GSK3B protein19694723
C0350553,4-dihydroxyphenyllactic acid"3,4-dihydroxyphenyllactic acid inhibits the reaction [tert-Butylhydroperoxide results in decreased phosphorylation of GSK3B protein]"29128606
C5622443-(5-(4-(2-hydroxy-2-methylpropionyl)piperazin-1-yl)-2-trifluoromethylphenyl)-4-(1H-indol-3-yl)pyrrole-2,5-dione"3-(5-(4-(2-hydroxy-2-methylpropionyl)piperazin-1-yl)-2-trifluoromethylphenyl)-4-(1H-indol-3-yl)pyrrole-2,5-dione results in decreased activity of GSK3B protein"21155605
C5307733,5-diethoxycarbonyl-1,4-dihydrocollidine"3,5-diethoxycarbonyl-1,4-dihydrocollidine results in increased phosphorylation of and results in decreased activity of GSK3B protein"20512997
C0087454,4'-bisphenol F"4,4'-bisphenol F results in decreased expression of GSK3B mRNA"26186136
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with entinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of GSK3B mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of GSK3B mRNA"27188386
C5550214-acetylantroquinonol B4-acetylantroquinonol B results in decreased phosphorylation of GSK3B protein28408137
C5529964-aminoethylamino-emodin4-aminoethylamino-emodin binds to and results in decreased activity of GSK3B protein19228266
C4943564-benzyl-2-methyl-1,2,4-thiadiazolidine-3,5-dione"4-benzyl-2-methyl-1,2,4-thiadiazolidine-3,5-dione results in decreased activity of GSK3B protein"24824809
C4943564-benzyl-2-methyl-1,2,4-thiadiazolidine-3,5-dione"4-benzyl-2-methyl-1,2,4-thiadiazolidine-3,5-dione inhibits the reaction [Kainic Acid results in decreased phosphorylation of GSK3B protein]"25453207
C4943564-benzyl-2-methyl-1,2,4-thiadiazolidine-3,5-dione"4-benzyl-2-methyl-1,2,4-thiadiazolidine-3,5-dione promotes the reaction [Valproic Acid inhibits the reaction [Kainic Acid results in decreased phosphorylation of GSK3B protein]]"25453207
C4943564-benzyl-2-methyl-1,2,4-thiadiazolidine-3,5-dione"4-benzyl-2-methyl-1,2,4-thiadiazolidine-3,5-dione results in decreased activity of GSK3B protein"22785175
C4943564-benzyl-2-methyl-1,2,4-thiadiazolidine-3,5-dione"4-benzyl-2-methyl-1,2,4-thiadiazolidine-3,5-dione results in decreased activity of GSK3B protein"15950778|2308512
C0275764-hydroxy-2-nonenal4-hydroxy-2-nonenal results in decreased expression of GSK3B mRNA12419474
C0275764-hydroxy-2-nonenal4-hydroxy-2-nonenal results in decreased phosphorylation of GSK3B protein24825450
C4067344-methylene-2-octyl-5-oxofuran-3-carboxylic acid4-methylene-2-octyl-5-oxofuran-3-carboxylic acid results in decreased phosphorylation of GSK3B protein21442130
C0165834-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone[4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased phosphorylation of and results in increased activity of AKT1 protein] which results in increased phosphorylation of GSK3B protein12511591
C0126064-vinyl-1-cyclohexene dioxide4-vinyl-1-cyclohexene dioxide affects the expression of GSK3B mRNA20829426
C0602985,7-dimethoxyflavone"5,7-dimethoxyflavone promotes the reaction [Diethylnitrosamine results in increased phosphorylation of GSK3B protein]"21554863
C4114255-aminoisoquinolinone2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [5-aminoisoquinolinone inhibits the reaction [Hydrogen Peroxide results in decreased phosphorylation of GSK3B protein]]23352507
C4114255-aminoisoquinolinone5-aminoisoquinolinone inhibits the reaction [Hydrogen Peroxide results in decreased phosphorylation of GSK3B protein]23352507
C4267455-iodo-3-(2-azetidinylmethoxy)pyridine[5-iodo-3-(2-azetidinylmethoxy)pyridine binds to and results in increased activity of CHRNB2 protein] inhibits the reaction [Okadaic Acid results in increased expression of GSK3B protein]21715663
C4267455-iodo-3-(2-azetidinylmethoxy)pyridine[5-iodo-3-(2-azetidinylmethoxy)pyridine binds to and results in increased activity of CHRNB2 protein] inhibits the reaction [Okadaic Acid results in increased expression of GSK3B protein modified form]21715663
C4267455-iodo-3-(2-azetidinylmethoxy)pyridine[5-iodo-3-(2-azetidinylmethoxy)pyridine binds to and results in increased activity of CHRNB2 protein] which results in increased phosphorylation of GSK3B protein21715663
C4718436-((3-chloro)anilino)-2-(isopropyl-2-hydroxyethylamino)-9-isopropylpurine6-((3-chloro)anilino)-2-(isopropyl-2-hydroxyethylamino)-9-isopropylpurine results in decreased activity of GSK3B protein15958644
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine inhibits the reaction [ginsenoside Rg2 results in increased phosphorylation of GSK3B protein]"22062806
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine inhibits the reaction [resveratrol results in decreased activity of GSK3B protein]"19620254
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine inhibits the reaction [resveratrol results in increased phosphorylation of GSK3B protein]"19620254
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with entinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of GSK3B mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of GSK3B mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine inhibits the reaction [[resveratrol results in increased phosphorylation of GSK3B protein] which results in increased uptake of Glucose]"22180358
C5582866,6'-bis(2,3-dimethoxybenzoyl)-alpha,alpha-trehalose"6,6'-bis(2,3-dimethoxybenzoyl)-alpha,alpha-trehalose analog results in decreased phosphorylation of GSK3B protein"25148938
C5582866,6'-bis(2,3-dimethoxybenzoyl)-alpha,alpha-trehalose"6,6'-bis(2,3-dimethoxybenzoyl)-alpha,alpha-trehalose analog results in increased expression of GSK3B mRNA"25148938
C4833216-bromoindirubin-3'-oxime6-bromoindirubin-3'-oxime promotes the reaction [Paraquat inhibits the reaction [TNFRSF10B protein binds to GSK3B protein]]28414160
C4833216-bromoindirubin-3'-oxime6-bromoindirubin-3'-oxime promotes the reaction [Paraquat results in decreased expression of GSK3B protein modified form]28414160
C4833216-bromoindirubin-3'-oxime6-bromoindirubin-3'-oxime results in decreased activity of GSK3B protein17991738
C4833216-bromoindirubin-3'-oxime6-bromoindirubin-3'-oxime results in increased phosphorylation of GSK3B protein19727391
C4833216-bromoindirubin-3'-oximeMethotrexate promotes the reaction [6-bromoindirubin-3'-oxime results in increased phosphorylation of GSK3B protein]19727391
C4833216-bromoindirubin-3'-oxime6-bromoindirubin-3'-oxime results in decreased activity of GSK3B protein18624906|2297544
C0538766-isopropoxy-9-oxoxanthene-2-carboxylic acid[6-isopropoxy-9-oxoxanthene-2-carboxylic acid co-treated with AH 23848] inhibits the reaction [GSK3B protein binds to AKT1 protein]19407222
C0538766-isopropoxy-9-oxoxanthene-2-carboxylic acid[6-isopropoxy-9-oxoxanthene-2-carboxylic acid co-treated with AH 23848] inhibits the reaction [GSK3B protein binds to MAPK1 protein binds to MAPK3 protein]19407222
C0538766-isopropoxy-9-oxoxanthene-2-carboxylic acid[6-isopropoxy-9-oxoxanthene-2-carboxylic acid co-treated with AH 23848] promotes the reaction [GSK3B protein binds to CTNNB1 protein]19407222
C0538766-isopropoxy-9-oxoxanthene-2-carboxylic acid[6-isopropoxy-9-oxoxanthene-2-carboxylic acid co-treated with AH 23848] results in decreased phosphorylation of GSK3B protein19407222
D000082AcetaminophenAcetaminophen results in increased expression of GSK3B protein modified form19679878
D000082AcetaminophenAcetaminophen results in increased phosphorylation of GSK3B protein22687999|2575261
D000082AcetaminophenGSTM1 gene mutant form inhibits the reaction [Acetaminophen results in increased phosphorylation of GSK3B protein]22687999
D000082AcetaminophenPARK2 gene mutant form affects the reaction [Acetaminophen results in increased phosphorylation of GSK3B protein]25752611
D000082AcetaminophenAcetaminophen affects the expression of GSK3B mRNA16701773
D000082AcetaminophenAcetaminophen results in decreased phosphorylation of GSK3B protein26767949
D000082Acetaminophenmorin inhibits the reaction [Acetaminophen results in decreased phosphorylation of GSK3B protein]26767949
D000111AcetylcysteineAcetylcysteine inhibits the reaction [arsenic trioxide results in increased phosphorylation of GSK3B protein]25246272
D000111AcetylcysteineAcetylcysteine inhibits the reaction [DDT results in increased phosphorylation of GSK3B protein]24968063
D000111AcetylcysteineAcetylcysteine inhibits the reaction [Fenretinide results in increased phosphorylation of GSK3B protein]25246272
D000111AcetylcysteineAcetylcysteine inhibits the reaction [phenethyl isothiocyanate results in increased phosphorylation of GSK3B protein]25246272
D000111AcetylcysteineAcetylcysteine inhibits the reaction [Cadmium results in increased phosphorylation of GSK3B protein]19126599
D000111AcetylcysteineAcetylcysteine inhibits the reaction [Chromium results in decreased phosphorylation of GSK3B protein]18569013
D000111AcetylcysteineAcetylcysteine inhibits the reaction [Cadmium results in increased phosphorylation of GSK3B protein]27658547
D000242Cyclic AMPGSK3B protein affects the reaction [Deamino Arginine Vasopressin results in increased abundance of Cyclic AMP]20056751
D016604Aflatoxin B1Aflatoxin B1 results in decreased methylation of GSK3B gene27153756
D016604Aflatoxin B1[CYP2A13 protein co-treated with Aflatoxin B1] results in increased phosphorylation of GSK3B protein26084420
D016604Aflatoxin B1MIR138-1 mRNA alternative form inhibits the reaction [[CYP2A13 protein co-treated with Aflatoxin B1] results in increased phosphorylation of GSK3B protein]26084420
C046926AH 23848[6-isopropoxy-9-oxoxanthene-2-carboxylic acid co-treated with AH 23848] inhibits the reaction [GSK3B protein binds to AKT1 protein]19407222
C046926AH 23848[6-isopropoxy-9-oxoxanthene-2-carboxylic acid co-treated with AH 23848] inhibits the reaction [GSK3B protein binds to MAPK1 protein binds to MAPK3 protein]19407222
C046926AH 23848[6-isopropoxy-9-oxoxanthene-2-carboxylic acid co-treated with AH 23848] promotes the reaction [GSK3B protein binds to CTNNB1 protein]19407222
C046926AH 23848[6-isopropoxy-9-oxoxanthene-2-carboxylic acid co-treated with AH 23848] results in decreased phosphorylation of GSK3B protein19407222
C000188alachlor[alachlor co-treated with Captan co-treated with Diazinon co-treated with Endosulfan co-treated with mancozeb co-treated with Maneb] affects the phosphorylation of GSK3B protein19883720
D0435825-alpha-Dihydroprogesterone5-alpha-Dihydroprogesterone results in decreased expression of GSK3B protein17443805
C120793alsterpaullonealsterpaullone results in decreased activity of GSK3B protein12534346
C120793alsterpaullonealsterpaullone results in decreased activity of GSK3B protein16055726
D000596Amino AcidsAmino Acids inhibits the reaction [KL gene mutant form results in decreased phosphorylation of GSK3B protein]25309793
D000596Amino AcidsH 1356 inhibits the reaction [Amino Acids inhibits the reaction [KL gene mutant form results in decreased phosphorylation of GSK3B protein]]25309793
D0151206-Aminonicotinamide6-Aminonicotinamide inhibits the reaction [Fenretinide results in increased phosphorylation of GSK3B protein]25246272
D000643Ammonium ChlorideAmmonium Chloride affects the expression of GSK3B mRNA16483693
D000661AmphetamineGSK3B gene mutant form results in increased susceptibility to Amphetamine20357757
D000661AmphetamineAmphetamine results in decreased expression of GSK3B protein16144542
C030419andrographolideandrographolide inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased phosphorylation of GSK3B protein]27475717
D000924Anticholesteremic AgentsAnticholesteremic Agents results in decreased phosphorylation of GSK3B protein28275691
D018501Antirheumatic AgentsAntirheumatic Agents results in increased expression of GSK3B mRNA24449571
C558369antrocinantrocin results in decreased phosphorylation of GSK3B protein21158420
C526219apple polyphenol extractapple polyphenol extract results in decreased activity of GSK3B protein16968061
C526219apple polyphenol extractapple polyphenol extract results in increased expression of GSK3B protein16968061
D016718Arachidonic Acid[SB 216763 results in decreased activity of GSK3B protein] results in decreased susceptibility to [Arachidonic Acid co-treated with Iron]19620254
D016718Arachidonic AcidGSK3B protein mutant form results in decreased susceptibility to [Arachidonic Acid co-treated with Iron]19620254
C071942arctigeninarctigenin results in decreased phosphorylation of GSK3B protein25380086
C071942arctigeninQuercetin promotes the reaction [arctigenin results in decreased phosphorylation of GSK3B protein]25380086
D001151ArsenicArsenic results in increased phosphorylation of GSK3B protein22552367
D001151ArsenicArsenic results in increased phosphorylation of GSK3B protein22552367
C006632arsenic trioxideAcetylcysteine inhibits the reaction [arsenic trioxide results in increased phosphorylation of GSK3B protein]25246272
C006632arsenic trioxidearsenic trioxide inhibits the reaction [sorafenib results in increased phosphorylation of GSK3B protein]25416439
C006632arsenic trioxidearsenic trioxide results in decreased phosphorylation of GSK3B protein25416439
C006632arsenic trioxidearsenic trioxide results in increased expression of GSK3B mRNA22521957
C006632arsenic trioxidearsenic trioxide results in increased phosphorylation of and results in increased activity of GSK3B protein23949314
C006632arsenic trioxide[arsenic trioxide results in increased phosphorylation of and results in increased activity of GSK3B protein] which results in increased phosphorylation of and results in increased ubiquitination of and results in increased degradation of CCND1 protein23949314
C006632arsenic trioxidearsenic trioxide results in increased phosphorylation of GSK3B protein21278055|2524627
C006632arsenic trioxideDeoxyglucose inhibits the reaction [arsenic trioxide results in increased phosphorylation of GSK3B protein]25246272
C006632arsenic trioxideGSK3B protein affects the susceptibility to arsenic trioxide21278055
C006632arsenic trioxideGSK3B protein modified form affects the reaction [arsenic trioxide results in increased expression of CDKN1A protein]21278055
C006632arsenic trioxidesorafenib inhibits the reaction [arsenic trioxide results in decreased phosphorylation of GSK3B protein]25416439
C006632arsenic trioxideU 0126 inhibits the reaction [arsenic trioxide results in increased phosphorylation of GSK3B protein]21278055
C006632arsenic trioxideMAP2K1 protein promotes the reaction [arsenic trioxide results in increased phosphorylation of GSK3B protein]21278055
C015001arsenitearsenite metabolite results in increased expression of GSK3B mRNA18242949
D017638Asbestos, Crocidolite"Asbestos, Crocidolite results in decreased phosphorylation of GSK3B protein"17191120
D001205Ascorbic AcidAscorbic Acid inhibits the reaction [Excitatory Amino Acid Agonists results in increased phosphorylation of GSK3B protein]24675465
D001205Ascorbic AcidAscorbic Acid results in decreased expression of GSK3B mRNA15372504
D001241AspirinAspirin results in decreased activity of GSK3B protein19966835
D001241AspirinAspirin results in decreased phosphorylation of GSK3B protein11593435
D001241AspirinAspirin results in increased phosphorylation of GSK3B protein12813129
D001280AtrazineAtrazine results in increased expression of GSK3B mRNA22378314
D001397AzoxymethaneAzoxymethane results in increased phosphorylation of GSK3B protein20681671
D001397Azoxymethanepterostilbene inhibits the reaction [Azoxymethane results in increased phosphorylation of GSK3B protein]20681671
C006680baicaleinbaicalein results in decreased phosphorylation of GSK3B protein22820424
C060988baohuoside Ibaohuoside I results in decreased phosphorylation of GSK3B protein25119583
C487081belinostatbelinostat results in increased phosphorylation of GSK3B protein23671600
D001554BenzeneBenzene analog results in decreased activity of GSK3B protein17764934
D001564Benzo(a)pyreneAHR protein promotes the reaction [Benzo(a)pyrene results in decreased expression of GSK3B mRNA]15034205
D001564Benzo(a)pyreneBenzo(a)pyrene results in decreased expression of GSK3B mRNA15034205
D001564Benzo(a)pyreneGSK3B protein affects the reaction [Benzo(a)pyrene results in increased expression of HK2 mRNA]22100782
D0151237,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide"7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide affects the expression of GSK3B mRNA"20382639
D0151237,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide"7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of GSK3B mRNA"19150397
C072553benzyloxycarbonylleucyl-leucyl-leucine aldehydebenzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Estradiol inhibits the reaction [ESR1 protein binds to GSK3B protein]]26990689
D001599BerberineBerberine inhibits the reaction [Glucose results in decreased phosphorylation of GSK3B protein]23954465
D001599BerberineBerberine results in increased phosphorylation of GSK3B protein23954465
D001599BerberineBerberine inhibits the reaction [Dexamethasone results in decreased expression of GSK3B mRNA]20462044
D004958Estradiolbenzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Estradiol inhibits the reaction [ESR1 protein binds to GSK3B protein]]26990689
D004958EstradiolEstradiol affects the expression of GSK3B mRNA22574217
D004958EstradiolEstradiol inhibits the reaction [ESR1 protein binds to GSK3B protein]26990689
D004958EstradiolEstradiol results in increased phosphorylation of GSK3B protein16076840
D004958Estradiolwortmannin inhibits the reaction [Estradiol results in increased phosphorylation of GSK3B protein]16076840
D004958Estradiol2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Estradiol results in increased phosphorylation of GSK3B protein]15845746
D004958EstradiolEstradiol results in increased phosphorylation of GSK3B protein15845746
D004958EstradiolProgesterone inhibits the reaction [Estradiol results in increased phosphorylation of GSK3B protein]15845746
D004958EstradiolEstradiol inhibits the reaction [Progesterone results in decreased expression of GSK3B mRNA]17170212
C044887beta-methylcholinebeta-methylcholine affects the expression of GSK3B mRNA21179406
D001632Bibenzyls"1,3-dihydro-1-(1-((4-(6-phenyl-1H-imidazo(4,5-g)quinoxalin-7-yl)phenyl)methyl)-4-piperidinyl)-2H-benzimidazol-2-one inhibits the reaction [Bibenzyls inhibits the reaction [Rotenone results in decreased phosphorylation of GSK3B protein]]"28245986
D001632BibenzylsBibenzyls inhibits the reaction [Rotenone results in decreased phosphorylation of GSK3B protein]28245986
D001632BibenzylsPARK7 protein affects the reaction [Bibenzyls inhibits the reaction [Rotenone results in decreased phosphorylation of GSK3B protein]]28245986
D001632Bibenzyls"1,3-dihydro-1-(1-((4-(6-phenyl-1H-imidazo(4,5-g)quinoxalin-7-yl)phenyl)methyl)-4-piperidinyl)-2H-benzimidazol-2-one inhibits the reaction [Bibenzyls inhibits the reaction [Rotenone results in decreased phosphorylation of GSK3B protein]]"28245986
D001632BibenzylsBibenzyls inhibits the reaction [Rotenone results in decreased phosphorylation of GSK3B protein]28245986
D001632BibenzylsPARK7 protein affects the reaction [Bibenzyls inhibits the reaction [Rotenone results in decreased phosphorylation of GSK3B protein]]28245986
C516541BI D1870BI D1870 inhibits the reaction [Fenretinide results in increased phosphorylation of GSK3B protein]25246272
C516541BI D1870BI D1870 results in decreased phosphorylation of GSK3B protein21488662
C528260bis(12)-hupyridonebis(12)-hupyridone results in increased expression of GSK3B protein modified form23085120
C577051bis(3)-cognitin"bis(3)-cognitin inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased phosphorylation of GSK3B protein]"22891246
C543008bis(4-hydroxyphenyl)sulfonebis(4-hydroxyphenyl)sulfone results in decreased expression of GSK3B mRNA26186136
C070515bisindolylmaleimide Ibisindolylmaleimide I results in decreased activity of GSK3B protein16055726
C467001bisindolylmaleimide IXbisindolylmaleimide IX results in decreased activity of GSK3B protein16055726
C006780bisphenol Abisphenol A inhibits the reaction [INS1 protein results in increased phosphorylation of GSK3B protein]28483554
C006780bisphenol Abisphenol A results in decreased phosphorylation of GSK3B protein25637671|2677993
C006780bisphenol Abisphenol A results in increased phosphorylation of GSK3B protein26923231
C006780bisphenol Abisphenol A promotes the reaction [Dietary Fats results in decreased phosphorylation of GSK3B protein]25112833
C006780bisphenol Abisphenol A results in decreased expression of GSK3B mRNA26186136
C006780bisphenol Abisphenol A results in decreased phosphorylation of GSK3B protein25112833|2596372
C006780bisphenol Abisphenol A results in increased expression of and results in decreased phosphorylation of GSK3B protein25381574
C006780bisphenol Abisphenol A results in increased expression of GSK3B mRNA25181051|2538157
C006780bisphenol Abisphenol A results in increased methylation of GSK3B gene28505145
C006780bisphenol ACurcumin inhibits the reaction [bisphenol A results in decreased phosphorylation of GSK3B protein]25963729
C006780bisphenol ACurcumin inhibits the reaction [bisphenol A results in increased expression of GSK3B mRNA]25963729
C006780bisphenol ACurcumin inhibits the reaction [bisphenol A results in increased phosphorylation of and affects the localization of GSK3B protein]25963729
C006780bisphenol ADietary Fats promotes the reaction [bisphenol A results in decreased phosphorylation of GSK3B protein]25112833
C006780bisphenol AGSK3B mutant form inhibits the reaction [bisphenol A results in increased phosphorylation of and affects the localization of GSK3B protein]25963729|2596372
C006780bisphenol AWNT3A protein affects the reaction [bisphenol A results in increased expression of and results in decreased phosphorylation of GSK3B protein]25381574
D001761Bleomycin[2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in decreased phosphorylation of GSK3B protein] which results in decreased susceptibility to Bleomycin19429264
D001761BleomycinBleomycin results in increased phosphorylation of GSK3B protein19429264
D001761Bleomycin[Bleomycin results in increased phosphorylation of GSK3B protein] inhibits the reaction [GSK3B protein binds to and results in increased stability of NFKBIA protein]19429264
D001786Blood Glucose[Oxygen deficiency co-treated with Blood Glucose deficiency] results in decreased phosphorylation of GSK3B protein24058562
D001786Blood Glucosesodium bisulfide inhibits the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in decreased phosphorylation of GSK3B protein]24058562
C428117BMS 191095BMS 191095 results in increased phosphorylation of GSK3B protein18212794
D000069286Bortezomib[Bortezomib co-treated with lonafarnib] results in decreased expression of GSK3B protein modified form16118318
C050295brazileinbrazilein results in decreased expression of GSK3B protein modified form23948132
C099813bromochloroacetic acidbromochloroacetic acid affects the expression of GSK3B mRNA16460773
D019328Buthionine SulfoximineButhionine Sulfoximine results in decreased phosphorylation of GSK3B protein18552690
C027561butylbenzyl phthalatebutylbenzyl phthalate results in increased phosphorylation of GSK3B protein22552774
C027561butylbenzyl phthalateHDAC6 mutant form inhibits the reaction [butylbenzyl phthalate results in increased phosphorylation of GSK3B protein]22552774
D020122tert-Butylhydroperoxide"3,4-dihydroxyphenyllactic acid inhibits the reaction [tert-Butylhydroperoxide results in decreased phosphorylation of GSK3B protein]"29128606
D020122tert-Butylhydroperoxidetert-Butylhydroperoxide results in decreased phosphorylation of GSK3B protein29128606
D020122tert-Butylhydroperoxidetert-Butylhydroperoxide results in increased expression of GSK3B mRNA15336504
D002104CadmiumCadmium results in increased phosphorylation of GSK3B protein22884995
D002104CadmiumCAT protein inhibits the reaction [Cadmium results in increased phosphorylation of GSK3B protein]22884995
D002104CadmiumGSK3B mutant form results in decreased susceptibility to Cadmium25273023
D002104Cadmium[GSK3B mutant form results in decreased susceptibility to Cadmium] which results in decreased expression of ABCC1 mRNA25273023
D002104Cadmium[GSK3B mutant form results in decreased susceptibility to Cadmium] which results in decreased expression of ABCC1 protein25273023
D002104CadmiumSOD1 protein inhibits the reaction [Cadmium results in increased phosphorylation of GSK3B protein]22884995
D002104CadmiumSOD2 protein inhibits the reaction [Cadmium results in increased phosphorylation of GSK3B protein]22884995
D002104CadmiumAcetylcysteine inhibits the reaction [Cadmium results in increased phosphorylation of GSK3B protein]19126599
D002104CadmiumCadmium results in increased phosphorylation of GSK3B protein19126599
D002104CadmiumGSK3B protein results in increased susceptibility to Cadmium19126599
D002104CadmiumAcetylcysteine inhibits the reaction [Cadmium results in increased phosphorylation of GSK3B protein]27658547
D002104Cadmium[Cadmium co-treated with rottlerin] results in decreased expression of GSK3B protein27658547
D002104CadmiumGSK3B protein affects the reaction [Cadmium results in increased cleavage of PARP1 protein]27658547
D002104CadmiumGSK3B protein affects the reaction [Cadmium results in increased expression of DDIT3 protein]27658547
D002104CadmiumGSK3B protein affects the reaction [Cadmium results in increased expression of HMOX1 protein]27658547
D002104CadmiumGSK3B protein affects the susceptibility to Cadmium27658547
D002104CadmiumLithium Chloride promotes the reaction [Cadmium results in increased phosphorylation of GSK3B protein]27658547
D002104Cadmiumrottlerin inhibits the reaction [Cadmium results in increased phosphorylation of GSK3B protein]27658547
D019256Cadmium ChlorideCadmium Chloride results in increased phosphorylation of and results in decreased activity of GSK3B protein28527916
D019256Cadmium ChlorideCadmium Chloride results in increased phosphorylation of GSK3B protein24057571|2511893
D019256Cadmium ChlorideACHE mRNA promotes the reaction [Cadmium Chloride results in increased expression of GSK3B mRNA]27377441
D019256Cadmium Chloride[[Cadmium Chloride results in decreased activity of CHRM1 protein] which affects the expression of ACHE mRNA alternative form] which results in increased expression of GSK3B mRNA27377441
D019256Cadmium Chloride[Cadmium Chloride results in decreased activity of CHRM1 protein] which results in increased expression of GSK3B mRNA27377441
D019256Cadmium ChlorideCadmium Chloride results in increased expression of GSK3B mRNA26026611|2737744
D019256Cadmium ChlorideCHRM1 mRNA inhibits the reaction [Cadmium Chloride results in increased expression of GSK3B mRNA]27377441
D019256Cadmium ChlorideGSK3B mutant form inhibits the reaction [Cadmium Chloride results in increased activity of CASP3 protein]26026611
D019256Cadmium ChlorideGSK3B mutant form inhibits the reaction [Cadmium Chloride results in increased activity of CASP7 protein]26026611
D019256Cadmium ChlorideGSK3B mutant form inhibits the reaction [Cadmium Chloride results in increased expression of and results in increased phosphorylation of MAPT protein]26026611
D002110CaffeineCaffeine results in increased phosphorylation of GSK3B protein21229324
D002110CaffeineN-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Caffeine results in increased phosphorylation of GSK3B protein]21229324
D002110CaffeineCaffeine results in decreased phosphorylation of GSK3B protein15126379
D002118CalciumCalcium results in increased phosphorylation of GSK3B protein15800129
C059041calyculin Acalyculin A promotes the reaction [Lithium Chloride results in increased phosphorylation of GSK3B protein]12813129
D002211CapsaicinCapsaicin promotes the reaction [CEBPB protein binds to ATF3 protein binds to GSK3B protein]20110283
D002211CapsaicinGSK3B mutant form inhibits the reaction [Capsaicin results in increased expression of GDF15 mRNA]20110283
D002215Captan[alachlor co-treated with Captan co-treated with Diazinon co-treated with Endosulfan co-treated with mancozeb co-treated with Maneb] affects the phosphorylation of GSK3B protein19883720
D002220CarbamazepineCarbamazepine affects the expression of GSK3B mRNA24752500
D002248Carbon MonoxideCarbon Monoxide inhibits the reaction [Doxorubicin results in decreased phosphorylation of GSK3B protein]18037988
D002248Carbon MonoxideCarbon Monoxide results in increased phosphorylation of GSK3B protein18845810
D000068579CelecoxibCelecoxib results in decreased phosphorylation of GSK3B protein17257745
D000068579CelecoxibGSK3B mutant form inhibits the reaction [Celecoxib results in increased expression of GDF15]17257745
D002518CeramidesCeramides promotes the reaction [IGF1 protein results in decreased phosphorylation of and results in increased activity of GSK3B protein]20696185
C019290chaetoglobosinschaetoglobosins results in increased phosphorylation of GSK3B protein18040759
C019290chaetoglobosinswortmannin inhibits the reaction [chaetoglobosins results in increased phosphorylation of GSK3B protein]18040759
C473711Chir 99021Chir 99021 affects the phosphorylation of GSK3B protein27752740
D048271Chitosan[Cromolyn Sodium co-treated with Chitosan] inhibits the reaction [Dimethylhydrazines results in increased expression of GSK3B protein]28732690
C084597chlorcyclizinechlorcyclizine results in decreased expression of GSK3B mRNA21058326
D005023Ethylene ChlorohydrinEthylene Chlorohydrin results in increased expression of GSK3B mRNA26962056
D002719ChlormethiazoleChlormethiazole inhibits the reaction [Ethanol results in decreased phosphorylation of GSK3B protein]24892905
C007020chlorophyllin"[chlorophyllin affects the reaction [1,2-Dimethylhydrazine results in increased mutagenesis of CTNNB1 gene]] inhibits the reaction [GSK3B protein results in increased phosphorylation of and results in increased ubiquitination of CTNNB1 protein]"12628520
C007020chlorophyllin"[chlorophyllin affects the reaction [2-amino-3-methylimidazo(4,5-f)quinoline results in increased mutagenesis of CTNNB1 gene]] inhibits the reaction [GSK3B protein results in increased phosphorylation of and results in increased ubiquitination of CTNNB1 protein]"12628520
D004390ChlorpyrifosChlorpyrifos results in decreased expression of GSK3B mRNA18668222
D002784CholesterolCholesterol results in increased phosphorylation of GSK3B protein28275691
D002784CholesterolCYP7A1 mRNA inhibits the reaction [Cholesterol results in increased phosphorylation of GSK3B protein]28275691
D002794Choline[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of GSK3B gene20938992
D002857ChromiumAcetylcysteine inhibits the reaction [Chromium results in decreased phosphorylation of GSK3B protein]18569013
D002857ChromiumChromium results in decreased phosphorylation of GSK3B protein18569013
C074702chromium hexavalent ionchromium hexavalent ion results in increased phosphorylation of GSK3B protein22552367
C045645cilostazolcilostazol affects the phosphorylation of GSK3B protein24254769
C045645cilostazolSIRT1 protein affects the reaction [cilostazol affects the phosphorylation of GSK3B protein]24254769
C012843cinnamic aldehydecinnamic aldehyde results in decreased expression of GSK3B mRNA28219650
C002471cinobufagincinobufagin results in increased expression of GSK3B protein modified form23164673
C002471cinobufaginGSK3B protein affects the susceptibility to cinobufagin23164673
C002471cinobufaginGSK3B protein mutant form inhibits the reaction [cinobufagin results in decreased expression of RELA protein]23164673
C002471cinobufaginGSK3B protein mutant form inhibits the reaction [cinobufagin results in increased expression of PARP1 protein modified form]23164673
C002471cinobufaginSB 216763 inhibits the reaction [cinobufagin results in increased expression of GSK3B protein modified form]23164673
D003024ClozapineClozapine results in increased phosphorylation of GSK3B protein19440698
D003024ClozapineClozapine results in increased expression of GSK3B protein16144542|1935914
D003024ClozapineDRD2 protein affects the reaction [Clozapine results in increased expression of GSK3B protein]16144542
C007095cobaltiprotoporphyrincobaltiprotoporphyrin affects the phosphorylation of GSK3B protein23497794
C007095cobaltiprotoporphyrincobaltiprotoporphyrin promotes the reaction [Oxygen deficiency results in increased phosphorylation of GSK3B protein]24658657
C007095cobaltiprotoporphyrintin protoporphyrin IX inhibits the reaction [cobaltiprotoporphyrin promotes the reaction [Oxygen deficiency results in increased phosphorylation of GSK3B protein]]24658657
C018021cobaltous chloride[lysophosphatidylethanolamine analog co-treated with cobaltous chloride] results in increased phosphorylation of GSK3B protein25125499
D003042CocaineCocaine results in decreased phosphorylation of and results in increased activity of GSK3B protein19328817
D003042CocaineCocaine results in increased activity of GSK3B protein19328817
D009243NADGSK3B protein mutant form results in increased abundance of NAD metabolite25246272
D009249NADPGSK3B protein mutant form results in increased abundance of NADP metabolite25246272
C024989coenzyme Q10coenzyme Q10 inhibits the reaction [APP protein results in decreased phosphorylation of GSK3B protein]22186599
D003078ColchicineColchicine results in decreased expression of GSK3B mRNA18255150
D003078ColchicineColchicine affects the phosphorylation of and results in increased activity of GSK3B protein15979805
D003078ColchicineLithium inhibits the reaction [Colchicine affects the phosphorylation of and results in increased activity of GSK3B protein]15979805
D005576ColforsinColforsin results in increased phosphorylation of and results in decreased activity of GSK3B protein15950778
D003300Copper[Copper binds to Thiosemicarbazones analog] which results in decreased activity of GSK3B protein19122148
D003300Copper[NSC 689534 binds to Copper] which results in increased expression of GSK3B mRNA20971185
D003300Copper[Thiosemicarbazones binds to Copper] which results in increased expression of GSK3B protein20931265
D019327Copper SulfateCopper Sulfate results in increased expression of GSK3B mRNA19549813
D004205Cromolyn Sodium[Cromolyn Sodium co-treated with Chitosan] inhibits the reaction [Dimethylhydrazines results in increased expression of GSK3B protein]28732690
D004205Cromolyn SodiumCromolyn Sodium results in decreased activity of GSK3B protein23784744
D003474CurcuminCurcumin inhibits the reaction [IL1B protein results in decreased expression of GSK3B mRNA]27645308
D003474CurcuminCurcumin inhibits the reaction [IL1B protein results in increased expression of GSK3B protein]27645308
D003474CurcuminCurcumin results in decreased expression of GSK3B mRNA27645308
D003474CurcuminCurcumin results in decreased phosphorylation of GSK3B protein18790744
D003474CurcuminCurcumin results in increased expression of and results in increased phosphorylation of GSK3B protein27645308
D003474CurcuminCurcumin results in increased expression of GSK3B protein19573523
D003474CurcuminCurcumin results in decreased phosphorylation of GSK3B protein18006147
D003474CurcuminCurcumin inhibits the reaction [bisphenol A results in decreased phosphorylation of GSK3B protein]25963729
D003474CurcuminCurcumin inhibits the reaction [bisphenol A results in increased expression of GSK3B mRNA]25963729
D003474CurcuminCurcumin inhibits the reaction [bisphenol A results in increased phosphorylation of and affects the localization of GSK3B protein]25963729
D003474CurcuminCurcumin inhibits the reaction [Streptozocin results in decreased phosphorylation of GSK3B protein]25541178
D003474CurcuminCurcumin results in decreased expression of GSK3B mRNA25963729
D003474CurcuminCurcumin results in increased phosphorylation of GSK3B protein25963729
C057862cyanoginosin LRcyanoginosin LR results in increased phosphorylation of GSK3B protein20421190
D003513CycloheximideCycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of GSK3B mRNA]11007951
D016572CyclosporineCyclosporine results in decreased expression of GSK3B mRNA22147139|2556210
D016572CyclosporineCyclosporine results in increased phosphorylation of GSK3B protein22416070
D016572Cyclosporine[GSK3A protein co-treated with GSK3B protein] affects the reaction [Cyclosporine results in increased expression of SNAI1 protein]22416070
D016572CyclosporineCyclosporine results in increased phosphorylation of GSK3B protein22416070
D003634DDTAcetylcysteine inhibits the reaction [DDT results in increased phosphorylation of GSK3B protein]24968063
D003634DDTDDT results in increased phosphorylation of GSK3B protein24968063
D003894Deamino Arginine VasopressinGSK3B protein affects the reaction [Deamino Arginine Vasopressin results in increased abundance of Cyclic AMP]20056751
D003676DeferoxamineDeferoxamine inhibits the reaction [Fenretinide results in increased phosphorylation of GSK3B protein]25246272
D003676DeferoxamineDeferoxamine results in decreased phosphorylation of GSK3B protein25246272
C107676deguelindeguelin results in decreased phosphorylation of GSK3B protein19336726|2147272
D013759DronabinolDronabinol results in decreased phosphorylation of GSK3B protein29082320
D013759Dronabinol[Dronabinol results in increased susceptibility to Dronabinol] which results in decreased phosphorylation of GSK3B protein29082320
D003847DeoxyglucoseDeoxyglucose inhibits the reaction [arsenic trioxide results in increased phosphorylation of GSK3B protein]25246272
D003847DeoxyglucoseDeoxyglucose inhibits the reaction [Fenretinide results in increased phosphorylation of GSK3B protein]25246272
C007262deoxynivalenoldeoxynivalenol results in increased phosphorylation of GSK3B protein15976193
D003907Dexamethasone[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased phosphorylation of GSK3B protein27475717
D003907Dexamethasoneandrographolide inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased phosphorylation of GSK3B protein]27475717
D003907DexamethasoneBerberine inhibits the reaction [Dexamethasone results in decreased expression of GSK3B mRNA]20462044
D003907DexamethasoneDexamethasone results in decreased expression of GSK3B mRNA20462044
D003907DexamethasoneDexamethasone results in increased expression of and results in decreased phosphorylation of GSK3B protein20501703
D003907DexamethasoneDexamethasone results in increased ubiquitination of GSK3B protein24451375
C028009diallyl disulfidediallyl disulfide results in increased phosphorylation of GSK3B protein23663050
C042577diallyl trisulfidediallyl trisulfide results in increased phosphorylation of GSK3B protein23663050
C042577diallyl trisulfidediallyl trisulfide results in decreased expression of GSK3B protein23453443
D003976Diazinon[alachlor co-treated with Captan co-treated with Diazinon co-treated with Endosulfan co-treated with mancozeb co-treated with Maneb] affects the phosphorylation of GSK3B protein19883720
D003976DiazinonDiazinon affects the expression of GSK3B mRNA22546817
D003993Dibutyl PhthalateDibutyl Phthalate results in increased phosphorylation of GSK3B protein22552774
D003993Dibutyl PhthalateHDAC6 mutant form inhibits the reaction [Dibutyl Phthalate results in increased phosphorylation of GSK3B protein]22552774
D003993Dibutyl PhthalateDibutyl Phthalate results in decreased expression of GSK3B mRNA21266533
D002945CisplatinCisplatin results in decreased expression of GSK3B mRNA27594783
D002945CisplatinCisplatin results in decreased phosphorylation of GSK3B protein21603599|2182100
D002945CisplatinGSK3B mutant form inhibits the reaction [Cisplatin results in increased expression of LGALS3 protein]21821001
D002945CisplatinCisplatin results in decreased expression of GSK3B mRNA21151649
D003633Dichlorodiphenyl DichloroethyleneDichlorodiphenyl Dichloroethylene affects the activity of GSK3B protein25386960
D004008DiclofenacDiclofenac affects the expression of GSK3B mRNA24752500
C036042dicyclohexyl phthalatedicyclohexyl phthalate affects the expression of GSK3B mRNA26924002
D004041Dietary FatsDietary Fats results in decreased expression of GSK3B mRNA18042831
D004041Dietary FatsDietary Fats results in increased expression of GSK3B mRNA24812660|2726046
D004041Dietary FatsQuercetin inhibits the reaction [Dietary Fats results in increased expression of GSK3B mRNA]27260466
D004041Dietary Fatsresveratrol inhibits the reaction [Dietary Fats results in increased expression of GSK3B mRNA]24812660|2726046
D004041Dietary FatsThioctic Acid inhibits the reaction [Dietary Fats results in increased expression of GSK3B mRNA]27260466
D004041Dietary Fatsbisphenol A promotes the reaction [Dietary Fats results in decreased phosphorylation of GSK3B protein]25112833
D004041Dietary FatsDietary Fats promotes the reaction [bisphenol A results in decreased phosphorylation of GSK3B protein]25112833
D004041Dietary FatsDietary Fats results in decreased phosphorylation of GSK3B protein25112833
D004051Diethylhexyl PhthalateDiethylhexyl Phthalate inhibits the reaction [INS1 protein results in increased phosphorylation of GSK3B protein]28526321
D004051Diethylhexyl PhthalateDiethylhexyl Phthalate results in decreased phosphorylation of GSK3B protein22610992
D004052DiethylnitrosamineCTNNB1 protein inhibits the reaction [Diethylnitrosamine results in increased phosphorylation of GSK3B protein]20583210
D004052DiethylnitrosamineDiethylnitrosamine affects the phosphorylation of GSK3B protein24535843
D004052DiethylnitrosamineDiethylnitrosamine results in increased phosphorylation of GSK3B protein20583210
D004052Diethylnitrosamine"5,7-dimethoxyflavone promotes the reaction [Diethylnitrosamine results in increased phosphorylation of GSK3B protein]"21554863
D004052DiethylnitrosamineDiethylnitrosamine results in increased expression of GSK3B protein modified form19931519
D004052DiethylnitrosamineDiethylnitrosamine results in increased phosphorylation of GSK3B protein21554863
D004052Diethylnitrosaminemorin inhibits the reaction [Diethylnitrosamine results in increased expression of GSK3B protein modified form]19931519
D0198131,2-Dimethylhydrazine"[chlorophyllin affects the reaction [1,2-Dimethylhydrazine results in increased mutagenesis of CTNNB1 gene]] inhibits the reaction [GSK3B protein results in increased phosphorylation of and results in increased ubiquitination of CTNNB1 protein]"12628520
D004127Dimethylhydrazines[Cromolyn Sodium co-treated with Chitosan] inhibits the reaction [Dimethylhydrazines results in increased expression of GSK3B protein]28732690
D004127DimethylhydrazinesDimethylhydrazines results in increased expression of GSK3B protein28732690
C024629dimethyl phthalatedimethyl phthalate results in decreased expression of GSK3B mRNA26924002
D004137DinitrochlorobenzeneDinitrochlorobenzene results in increased expression of GSK3B mRNA17374397
D004137DinitrochlorobenzeneDinitrochlorobenzene results in increased expression of GSK3B mRNA28219650
D004221DisulfiramDisulfiram results in decreased expression of GSK3B mRNA20530235
D016291Dizocilpine MaleateDizocilpine Maleate results in increased phosphorylation of GSK3B protein15877933
D004280DobutamineGSK3B gene mutant form affects the susceptibility to Dobutamine17901358
D007980LevodopaEPO protein inhibits the reaction [Levodopa results in decreased expression of GSK3B protein]21683736
D007980LevodopaLevodopa results in decreased expression of GSK3B protein21683736
D007980LevodopaLevodopa results in decreased phosphorylation of GSK3B protein19786063
D004317DoxorubicinDoxorubicin results in increased phosphorylation of GSK3B protein17339365
D004317Doxorubicinmethylselenic acid inhibits the reaction [Doxorubicin results in increased phosphorylation of GSK3B protein]17339365
D004317DoxorubicinSelenium inhibits the reaction [Doxorubicin results in increased phosphorylation of GSK3B protein]17339365
D004317DoxorubicinCarbon Monoxide inhibits the reaction [Doxorubicin results in decreased phosphorylation of GSK3B protein]18037988
D004317DoxorubicinDoxorubicin results in decreased phosphorylation of GSK3B protein18037988
D004365Drugs, Chinese Herbal"Drugs, Chinese Herbal results in increased expression of and results in decreased phosphorylation of GSK3B protein"28548306
D004365Drugs, Chinese Herbal"PPP2CA protein affects the reaction [Drugs, Chinese Herbal results in decreased phosphorylation of GSK3B protein]"28548306
D004656EnalaprilEnalapril inhibits the reaction [Isoproterenol results in decreased phosphorylation of GSK3B protein]18806606
D004726Endosulfan[alachlor co-treated with Captan co-treated with Diazinon co-treated with Endosulfan co-treated with mancozeb co-treated with Maneb] affects the phosphorylation of GSK3B protein19883720
C044101endotoxin, Escherichia coli"[endotoxin, Escherichia coli results in increased phosphorylation of and results in increased activity of AKT1 protein] which results in increased phosphorylation of GSK3B protein"23755222
C044101endotoxin, Escherichia coli"malvidin promotes the reaction [[endotoxin, Escherichia coli results in increased phosphorylation of and results in increased activity of AKT1 protein] which results in increased phosphorylation of GSK3B protein]"23755222
C040996enkephalin-Leu, Ala(2)-Arg(6)-"enkephalin-Leu, Ala(2)-Arg(6)- results in increased phosphorylation of GSK3B protein"23651617
C118739entinostatentinostat results in decreased expression of GSK3B mRNA26272509
C118739entinostat"[NOG protein co-treated with entinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of GSK3B mRNA"27188386
C045651epigallocatechin gallateepigallocatechin gallate results in increased phosphorylation of GSK3B protein16968065
C045651epigallocatechin gallate[potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of GSK3B mRNA22079256
C007633estragoleestragole results in increased phosphorylation of GSK3B protein29054680
D000431EthanolALDH2 protein inhibits the reaction [Ethanol results in decreased phosphorylation of GSK3B protein]19429258
D000431Ethanol[Ethanol co-treated with sodium arsenite] results in increased phosphorylation of GSK3B protein26220687
D000431EthanolEthanol results in decreased activity of and affects the phosphorylation of GSK3B protein26014148
D000431EthanolEthanol results in increased phosphorylation of GSK3B protein26220687
D000431Ethanol[sodium arsenite co-treated with Ethanol] results in increased phosphorylation of GSK3B protein22872060
D000431EthanolALDH2 protein inhibits the reaction [Ethanol results in increased phosphorylation of GSK3B protein]19332462
D000431EthanolChlormethiazole inhibits the reaction [Ethanol results in decreased phosphorylation of GSK3B protein]24892905
D000431EthanolEthanol results in decreased phosphorylation of GSK3B protein18377926|1942925
D000431EthanolEthanol results in increased phosphorylation of GSK3B protein19332462|2245917
D000431EthanolNR1H4 gene mutant form inhibits the reaction [Ethanol results in decreased phosphorylation of GSK3B protein]25460735
D000431Ethanoltetrakis(N-methyl-4-pyridiniumyl)porphine manganese(III) complex inhibits the reaction [Ethanol results in increased phosphorylation of GSK3B protein]28962519
D000431Ethanol[Ethanol results in decreased susceptibility to INS1 protein] which results in increased activity of GSK3B protein12700235
D000431EthanolEthanol results in increased activity of and results in decreased phosphorylation of GSK3B protein12700235
D004997Ethinyl EstradiolEthinyl Estradiol results in increased expression of GSK3B mRNA12655037|1557682
D005013EthosuximideDKK1 protein inhibits the reaction [Ethosuximide results in increased phosphorylation of GSK3B protein]26420483
D005013EthosuximideEthosuximide inhibits the reaction [APP protein modified form results in increased expression of GSK3B mRNA]26420483
D005013EthosuximideEthosuximide results in decreased expression of GSK3B mRNA26420483
D005013EthosuximideEthosuximide results in increased phosphorylation of GSK3B protein26420483
D005020Ethyl MethanesulfonateEthyl Methanesulfonate results in increased expression of GSK3B mRNA23649840
D005038EthylnitrosoureaEthylnitrosourea results in decreased expression of GSK3B protein28549617
D005047EtoposideBCL2 protein affects the reaction [[Etoposide results in increased activity of GSK3B protein] which results in increased activity of CASP3 protein]19408126
D005047EtoposideEtoposide results in increased activity of GSK3B protein19408126
D005047Etoposide[Etoposide results in increased activity of GSK3B protein] which results in increased activity of CASP3 protein19408126
D005054EugenolEugenol results in increased expression of GSK3B mRNA17374397
D018683Excitatory Amino Acid Agents[resveratrol co-treated with Excitatory Amino Acid Agents] results in increased phosphorylation of and results in decreased activity of GSK3B protein20542495
D018690Excitatory Amino Acid AgonistsExcitatory Amino Acid Agonists affects the phosphorylation of GSK3B protein24675465
D018690Excitatory Amino Acid Agonistsresveratrol inhibits the reaction [Excitatory Amino Acid Agonists affects the phosphorylation of GSK3B protein]24675465
D018690Excitatory Amino Acid AgonistsAscorbic Acid inhibits the reaction [Excitatory Amino Acid Agonists results in increased phosphorylation of GSK3B protein]24675465
D018690Excitatory Amino Acid AgonistsExcitatory Amino Acid Agonists affects the phosphorylation of and results in increased activity of GSK3B protein24675465
D018690Excitatory Amino Acid AgonistsGSK3B protein results in increased susceptibility to Excitatory Amino Acid Agonists24675465
D018690Excitatory Amino Acid Agonistsresveratrol inhibits the reaction [Excitatory Amino Acid Agonists affects the phosphorylation of GSK3B protein]24675465
D018690Excitatory Amino Acid AgonistsSB 216763 inhibits the reaction [Excitatory Amino Acid Agonists affects the phosphorylation of GSK3B protein]24675465
C020748ferrous sulfateferrous sulfate results in increased phosphorylation of GSK3B protein19608791
C082360fipronilfipronil results in decreased phosphorylation of GSK3B protein21296133
C082360fipronilGSK3B protein affects the susceptibility to fipronil21296133
C082360fipronilkenpaullone inhibits the reaction [fipronil results in decreased phosphorylation of GSK3B protein]21296133
C082360fipronilLithium Chloride inhibits the reaction [fipronil results in decreased phosphorylation of GSK3B protein]21296133
D005473FluoxetineFluoxetine results in increased expression of GSK3B protein19359144
D005492Folic AcidFolic Acid results in increased expression of GSK3B mRNA25006883
D005492Folic Acid[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of GSK3B gene20938992
D005557FormaldehydeFormaldehyde results in increased expression of GSK3B mRNA23649840
C058728fosbretabulinfosbretabulin results in decreased expression of GSK3B protein modified form18434188
C070081fulvestrantfulvestrant inhibits the reaction [notoginsenoside R1 inhibits the reaction [Lipopolysaccharides results in decreased expression of GSK3B protein modified form]]23170834
C070081fulvestrantfulvestrant inhibits the reaction [gypenoside analog results in increased phosphorylation of GSK3B protein]24726523
C070081fulvestrantfulvestrant inhibits the reaction [Phytoestrogens results in increased phosphorylation of GSK3B protein]24726523
C000599091fumosorinonefumosorinone results in increased phosphorylation of GSK3B protein25796170
C052659gambogic acidgambogic acid results in decreased activity of GSK3B protein19433130
C056507gemcitabinegemcitabine results in increased phosphorylation of GSK3B protein16570353
D019833GenisteinGenistein results in decreased phosphorylation of GSK3B protein18431742
C007845gingerolgingerol inhibits the reaction [IL1B protein results in increased expression of GSK3B protein]27645308
C007845gingerolgingerol inhibits the reaction [IL1B protein results in increased phosphorylation of GSK3B protein]27645308
C007845gingerolgingerol results in increased expression of GSK3B protein27645308
C007845gingerolGSK3B protein affects the reaction [gingerol results in increased expression of GDF15 protein]18058799
C007845gingerolgingerol results in increased phosphorylation of GSK3B protein26498061
C007845gingerolGSK3B protein promotes the reaction [gingerol results in decreased expression of CEBPA mRNA]26498061
C007845gingerolGSK3B protein promotes the reaction [gingerol results in decreased expression of CEBPA protein]26498061
C007845gingerolGSK3B protein promotes the reaction [gingerol results in decreased expression of PPARG mRNA]26498061
C007845gingerolGSK3B protein promotes the reaction [gingerol results in decreased expression of PPARG protein]26498061
C007845gingerolGSK3B protein results in increased susceptibility to gingerol26498061
C049864ginsenoside Reginsenoside Re results in increased phosphorylation of GSK3B protein17885204
C026474ginsenoside Rg2"(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine inhibits the reaction [ginsenoside Rg2 results in increased phosphorylation of GSK3B protein]"22062806
C026474ginsenoside Rg2ginsenoside Rg2 results in increased phosphorylation of GSK3B protein22062806
C026474ginsenoside Rg2[[ginsenoside Rg2 results in increased phosphorylation of GSK3B protein] co-treated with [ginsenoside Rg2 results in increased expression of NR0B2 mRNA]] results in decreased chemical synthesis of Glucose22062806
D005947GlucoseBerberine inhibits the reaction [Glucose results in decreased phosphorylation of GSK3B protein]23954465
D005947Glucose[[ginsenoside Rg2 results in increased phosphorylation of GSK3B protein] co-treated with [ginsenoside Rg2 results in increased expression of NR0B2 mRNA]] results in decreased chemical synthesis of Glucose22062806
D005947GlucoseGlucose results in decreased phosphorylation of GSK3B protein23954465
D005947GlucoseGlucose results in increased phosphorylation of GSK3B protein23690508
D005947Glucose"(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine inhibits the reaction [[resveratrol results in increased phosphorylation of GSK3B protein] which results in increased uptake of Glucose]"22180358
D005947Glucose[resveratrol results in increased phosphorylation of GSK3B protein] which results in increased uptake of Glucose22180358
D005947GlucoseGlucose results in decreased phosphorylation of and results in increased activity of GSK3B protein18004065
D005947GlucoseGlucose results in decreased phosphorylation of GSK3B protein26054749
D005947GlucoseSimvastatin inhibits the reaction [Glucose results in decreased phosphorylation of and results in increased activity of GSK3B protein]18004065
D005947Glucose[INS protein co-treated with Glucose] results in decreased expression of GSK3B mRNA22634610
D005947Glucose[INS protein co-treated with Glucose] results in increased expression of GSK3B mRNA22634610
D005978GlutathioneGSK3B protein mutant form results in increased abundance of Glutathione25246272
C474918gypenoside2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [gypenoside analog results in increased phosphorylation of GSK3B protein]24726523
C474918gypenosidefulvestrant inhibits the reaction [gypenoside analog results in increased phosphorylation of GSK3B protein]24726523
C474918gypenosidegypenoside analog results in increased phosphorylation of GSK3B protein24726523
C411572H 1356H 1356 inhibits the reaction [Amino Acids inhibits the reaction [KL gene mutant form results in decreased phosphorylation of GSK3B protein]]25309793
D006220HaloperidolDRD2 protein affects the reaction [Haloperidol results in increased expression of GSK3B protein]16144542
D006220HaloperidolHaloperidol results in increased expression of GSK3B mRNA19359144
D006220HaloperidolHaloperidol results in increased expression of GSK3B protein16144542|1935914
D006220HaloperidolHaloperidol results in increased phosphorylation of and results in decreased activity of GSK3B protein19328817
D006581HexachlorobenzeneHexachlorobenzene results in decreased activity of GSK3B protein16679308
D006581Hexachlorobenzene[Hexachlorobenzene results in decreased activity of GSK3B protein] which results in decreased expression of CDH1 protein16679308
D017313Fenretinide6-Aminonicotinamide inhibits the reaction [Fenretinide results in increased phosphorylation of GSK3B protein]25246272
D017313FenretinideAcetylcysteine inhibits the reaction [Fenretinide results in increased phosphorylation of GSK3B protein]25246272
D017313FenretinideBI D1870 inhibits the reaction [Fenretinide results in increased phosphorylation of GSK3B protein]25246272
D017313FenretinideDeferoxamine inhibits the reaction [Fenretinide results in increased phosphorylation of GSK3B protein]25246272
D017313FenretinideDeoxyglucose inhibits the reaction [Fenretinide results in increased phosphorylation of GSK3B protein]25246272
D017313FenretinideFenretinide results in increased phosphorylation of GSK3B protein25246272
D017313FenretinideGSK3B protein mutant form inhibits the reaction [Fenretinide results in increased expression of HMOX1 protein]25246272
D017313FenretinideGSK3B protein mutant form inhibits the reaction [Fenretinide results in increased phosphorylation of GSK3B protein]25246272
D017313FenretinideS-ethyl glutathione inhibits the reaction [Fenretinide results in increased phosphorylation of GSK3B protein]25246272
D017313FenretinideU 0126 inhibits the reaction [Fenretinide results in increased phosphorylation of GSK3B protein]25246272
D017313FenretinideFenretinide results in decreased expression of GSK3B mRNA28973697
D012701SerotoninSerotonin results in increased phosphorylation of GSK3B protein20190034
C062018HU 211HU 211 results in decreased phosphorylation of GSK3B protein19509271
D006861Hydrogen PeroxideHydrogen Peroxide affects the expression of GSK3B mRNA21179406
D006861Hydrogen PeroxideHydrogen Peroxide results in increased phosphorylation of GSK3B protein20302854
D006861Hydrogen PeroxideMycophenolic Acid inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of GSK3B protein]20302854
D006861Hydrogen Peroxide2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [5-aminoisoquinolinone inhibits the reaction [Hydrogen Peroxide results in decreased phosphorylation of GSK3B protein]]23352507
D006861Hydrogen Peroxide5-aminoisoquinolinone inhibits the reaction [Hydrogen Peroxide results in decreased phosphorylation of GSK3B protein]23352507
D006861Hydrogen PeroxideHydrogen Peroxide results in decreased phosphorylation of GSK3B protein23352507
D004441Ecdysterone2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Ecdysterone inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased phosphorylation of and results in decreased activity of GSK3B protein]]26048653
D004441EcdysteroneEcdysterone inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased phosphorylation of and results in decreased activity of GSK3B protein]26048653
C107079hymenialdisinehymenialdisine results in decreased activity of GSK3B protein21615147
C477872IC 87114IC 87114 results in decreased phosphorylation of GSK3B protein16179367
D007093ImidazolesImidazoles analog results in decreased activity of GSK3B protein17764934
C474021indirubin-3'-monoximeindirubin-3'-monoxime results in decreased activity of GSK3B protein12534346
D007213IndomethacinIndomethacin results in increased expression of GSK3B mRNA18299717
D007501Iron[SB 216763 results in decreased activity of GSK3B protein] results in decreased susceptibility to [Arachidonic Acid co-treated with Iron]19620254
D007501IronGSK3B protein mutant form results in decreased susceptibility to [Arachidonic Acid co-treated with Iron]19620254
D0150561-Methyl-3-isobutylxanthine[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased phosphorylation of GSK3B protein27475717
D0150561-Methyl-3-isobutylxanthineandrographolide inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased phosphorylation of GSK3B protein]27475717
D007545Isoproterenol2-((2-piperidin-1-ylethyl)thio)quinazolin-4(3H)-one inhibits the reaction [Isoproterenol results in decreased phosphorylation of GSK3B protein]18806606
D007545Isoproterenol2-((2-piperidin-1-ylethyl)thio)quinazolin-4(3H)-one inhibits the reaction [Isoproterenol results in increased phosphorylation of GSK3B protein]16716347
D007545Isoproterenol2-((2-piperidin-1-ylethyl)thio)quinazolin-4(3H)-one promotes the reaction [Isoproterenol results in increased phosphorylation of GSK3B protein]15951400
D007545IsoproterenolEnalapril inhibits the reaction [Isoproterenol results in decreased phosphorylation of GSK3B protein]18806606
D007545IsoproterenolIsoproterenol results in decreased phosphorylation of GSK3B protein18806606
D007545IsoproterenolIsoproterenol results in increased phosphorylation of GSK3B protein15951400|1671634
C053401kahweolkahweol results in increased phosphorylation of GSK3B protein27424123
D007608Kainic Acid"4-benzyl-2-methyl-1,2,4-thiadiazolidine-3,5-dione inhibits the reaction [Kainic Acid results in decreased phosphorylation of GSK3B protein]"25453207
D007608Kainic Acid"4-benzyl-2-methyl-1,2,4-thiadiazolidine-3,5-dione promotes the reaction [Valproic Acid inhibits the reaction [Kainic Acid results in decreased phosphorylation of GSK3B protein]]"25453207
D007608Kainic AcidKainic Acid results in decreased activity of GSK3B protein18619545
D007608Kainic AcidKainic Acid results in decreased phosphorylation of GSK3B protein25453207
D007608Kainic AcidValproic Acid inhibits the reaction [Kainic Acid results in decreased phosphorylation of GSK3B protein]25453207
C510621KCC 009KCC 009 results in decreased expression of GSK3B protein16170020
C510621KCC 009KCC 009 results in decreased phosphorylation of and results in increased activity of GSK3B protein16170020
C119620kenpaullonekenpaullone inhibits the reaction [fipronil results in decreased phosphorylation of GSK3B protein]21296133
C119620kenpaullonekenpaullone results in decreased activity of GSK3B protein12534346|2111172
C119620kenpaullonekenpaullone results in decreased phosphorylation of GSK3B protein17993264
C119620kenpaullonekenpaullone results in decreased activity of GSK3B protein18624906|2297544
D007649KetamineKetamine results in decreased phosphorylation of GSK3B protein17952604
C063302KN 62KN 62 results in decreased activity of GSK3B protein10998351
C073601KT 5823KT 5823 results in decreased activity of GSK3B protein12534346
D007854LeadLead affects the splicing of GSK3B mRNA28903495
C008261lead acetatelead acetate results in increased phosphorylation of GSK3B protein27012722
D044243Linoleic Acids, Conjugated"Linoleic Acids, Conjugated results in decreased phosphorylation of GSK3B protein"19800873
D044243Linoleic Acids, Conjugated"Linoleic Acids, Conjugated results in increased activity of GSK3B protein"19800873
D008070Lipopolysaccharidesfulvestrant inhibits the reaction [notoginsenoside R1 inhibits the reaction [Lipopolysaccharides results in decreased expression of GSK3B protein modified form]]23170834
D008070LipopolysaccharidesLipopolysaccharides results in decreased expression of GSK3B protein modified form23170834
D008070Lipopolysaccharidesnotoginsenoside R1 inhibits the reaction [Lipopolysaccharides results in decreased expression of GSK3B protein modified form]23170834
D008070Lipopolysaccharideswortmannin inhibits the reaction [notoginsenoside R1 inhibits the reaction [Lipopolysaccharides results in decreased expression of GSK3B protein modified form]]23170834
D008070LipopolysaccharidesLipopolysaccharides results in increased phosphorylation of GSK3B protein18047562
D008070LipopolysaccharidesSimvastatin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of GSK3B protein]18047562
D008094LithiumLithium results in decreased activity of GSK3B protein19932742
D008094LithiumLithium inhibits the reaction [GSK3B protein binds to TP53 protein]15475000
D008094LithiumLithium promotes the reaction [sodium arsenite results in increased phosphorylation of GSK3B protein]17849503
D008094LithiumLithium results in decreased activity of GSK3B protein10998351
D008094LithiumLithium results in increased phosphorylation of GSK3B protein15475000|1944069
D008094LithiumMagnesium affects the reaction [Lithium results in decreased activity of GSK3B protein]10998351
D008094LithiumLithium results in decreased activity of GSK3B protein19621015
D008094Lithium[Lithium results in decreased activity of GSK3B protein] which results in increased activity of MTOR protein17921520
D008094Lithium[Lithium results in decreased activity of GSK3B protein] which results in increased activity of NFE2L2 protein18619545
D008094LithiumLithium results in increased phosphorylation of and results in decreased activity of GSK3B protein19328817
D008094LithiumLithium results in decreased activity of GSK3B protein16288908
D008094LithiumLithium results in decreased phosphorylation of GSK3B protein25433145
D008094LithiumLithium results in increased expression of GSK3B mRNA19359144
D008094LithiumLithium results in increased expression of GSK3B protein18296634|1935914
D008094LithiumLithium results in increased phosphorylation of and results in decreased activity of GSK3B protein15950778|2171190
D008094LithiumLithium results in increased phosphorylation of GSK3B protein18296634
D008094LithiumLithium inhibits the reaction [Colchicine affects the phosphorylation of and results in increased activity of GSK3B protein]15979805
D008094LithiumLithium results in decreased activity of GSK3B protein14534419|1792152
D018021Lithium ChlorideLithium Chloride results in decreased activity of GSK3B protein19486905
D018021Lithium Chloride[Lithium Chloride results in decreased activity of GSK3B protein] which results in increased expression of SCN9A mRNA19486905
D018021Lithium ChlorideCTNNB1 protein affects the reaction [[Lithium Chloride results in decreased activity of GSK3B protein] which results in decreased expression of CDH11 protein]19274078
D018021Lithium ChlorideGSK3B protein mutant form inhibits the reaction [Lithium Chloride results in decreased expression of and results in decreased activity of ACHE protein]22944069
D018021Lithium ChlorideGSK3B protein mutant form inhibits the reaction [Lithium Chloride results in increased degradation of ACHE protein]22944069
D018021Lithium ChlorideLithium Chloride inhibits the reaction [fipronil results in decreased phosphorylation of GSK3B protein]21296133
D018021Lithium ChlorideLithium Chloride promotes the reaction [quinocetone affects the phosphorylation of and results in decreased activity of GSK3B protein]28343033
D018021Lithium ChlorideLithium Chloride results in decreased activity of and results in increased phosphorylation of GSK3B protein22493441
D018021Lithium Chloride[Lithium Chloride results in decreased activity of and results in increased phosphorylation of GSK3B protein] which results in increased expression of and results in increased phosphorylation of CTNNB1 protein22493441
D018021Lithium Chloride[Lithium Chloride results in decreased activity of and results in increased phosphorylation of GSK3B protein] which results in increased expression of EGFR mRNA22493441
D018021Lithium Chloride[Lithium Chloride results in decreased activity of and results in increased phosphorylation of GSK3B protein] which results in increased expression of EGFR protein22493441
D018021Lithium ChlorideLithium Chloride results in decreased activity of GSK3B protein19101580|1927407
D018021Lithium Chloride[Lithium Chloride results in decreased activity of GSK3B protein] inhibits the reaction [Sirolimus results in decreased expression of CCND1 protein]15753396
D018021Lithium Chloride[Lithium Chloride results in decreased activity of GSK3B protein] which results in decreased expression of CDH11 mRNA19274078
D018021Lithium Chloride[Lithium Chloride results in decreased activity of GSK3B protein] which results in decreased expression of CDH11 protein19274078
D018021Lithium Chloride[Lithium Chloride results in decreased activity of GSK3B protein] which results in increased expression of HSPA1A protein alternative form20090934
D018021Lithium Chloride[Lithium Chloride results in decreased activity of GSK3B protein] which results in increased expression of STARD7 mRNA19679347
D018021Lithium Chloride[Lithium Chloride results in decreased activity of GSK3B protein] which results in increased expression of STARD7 protein19679347
D018021Lithium ChlorideLithium Chloride results in decreased expression of and results in increased phosphorylation of GSK3B protein26990689
D018021Lithium ChlorideLithium Chloride results in decreased phosphorylation of GSK3B protein20093106
D018021Lithium ChlorideLithium Chloride results in increased expression of and results in increased phosphorylation of and results in decreased activity of GSK3B protein19196980
D018021Lithium ChlorideLithium Chloride results in increased expression of GSK3B protein modified form22944069
D018021Lithium ChlorideLithium Chloride results in increased phosphorylation of and results in decreased activity of GSK3B protein17868649|1967934
D018021Lithium ChlorideLithium Chloride results in increased phosphorylation of GSK3B protein18830594|2069614
D018021Lithium ChloridePIK3CA protein affects the reaction [Lithium Chloride results in increased phosphorylation of and results in decreased activity of GSK3B protein]19196980
D018021Lithium ChlorideLithium Chloride inhibits the reaction [Okadaic Acid affects the phosphorylation of GSK3B protein]27050422
D018021Lithium ChlorideLithium Chloride inhibits the reaction [perfluorooctane sulfonic acid results in decreased phosphorylation of GSK3B protein]27018151
D018021Lithium ChlorideLithium Chloride results in decreased activity of GSK3B protein15364539|1558566
D018021Lithium Chloride[Lithium Chloride results in decreased activity of GSK3B protein] which results in increased expression of AHR mRNA21498875
D018021Lithium Chloride[Lithium Chloride results in decreased activity of GSK3B protein] which results in increased expression of AXIN2 mRNA21498875
D018021Lithium ChlorideLithium Chloride results in increased phosphorylation of and results in decreased activity of GSK3B protein19440036|1958239
D018021Lithium Chloride[Lithium Chloride results in increased phosphorylation of and results in decreased activity of GSK3B protein] which results in decreased expression of SNAI1 protein19440036
D018021Lithium Chloride[Lithium Chloride results in increased phosphorylation of and results in decreased activity of GSK3B protein] which results in increased localization of CTNNB1 protein19582394
D018021Lithium Chloride[[Lithium Chloride results in increased phosphorylation of and results in decreased activity of GSK3B protein] which results in increased localization of CTNNB1 protein] which results in increased expression of GIP mRNA19582394
D018021Lithium ChlorideLithium Chloride results in increased phosphorylation of GSK3B protein27018151
D018021Lithium ChlorideLithium Chloride results in increased stability of GSK3B protein19448134
D018021Lithium Chloridecalyculin A promotes the reaction [Lithium Chloride results in increased phosphorylation of GSK3B protein]12813129
D018021Lithium ChlorideLithium Chloride affects the phosphorylation of GSK3B protein21364661
D018021Lithium ChlorideLithium Chloride inhibits the reaction [manganese chloride results in decreased phosphorylation of and results in increased activity of GSK3B protein]24464479
D018021Lithium ChlorideLithium Chloride inhibits the reaction [sevoflurane results in decreased phosphorylation of GSK3B protein]20807582
D018021Lithium ChlorideLithium Chloride promotes the reaction [Cadmium results in increased phosphorylation of GSK3B protein]27658547
D018021Lithium ChlorideLithium Chloride results in decreased activity of GSK3B protein15247282|1897223
D018021Lithium Chloride[Lithium Chloride results in decreased activity of GSK3B protein] inhibits the reaction [manganese chloride results in increased phosphorylation of MAPT protein]20937724
D018021Lithium Chloride[Lithium Chloride results in decreased activity of GSK3B protein] which results in increased expression of CTNNB1 protein18972237
D018021Lithium Chloride[[Lithium Chloride results in decreased activity of GSK3B protein] which results in increased expression of CTNNB1 protein] which affects the expression of GJA1 protein18972237
D018021Lithium ChlorideLithium Chloride results in decreased expression of GSK3B mRNA18932008
D018021Lithium ChlorideLithium Chloride results in increased phosphorylation of and results in decreased activity of GSK3B protein12813129|2645918
D018021Lithium ChlorideLithium Chloride results in increased phosphorylation of GSK3B protein23651617|2765854
D018021Lithium ChlorideLithium Chloride results in decreased activity of [GSK3A protein binds to GSK3B protein]16076840
D018021Lithium ChlorideLithium Chloride results in decreased activity of GSK3B protein16055726|1721070
D018021Lithium Chloride[Lithium Chloride results in decreased activity of GSK3B protein] which results in increased expression of CTNNB123872260
D008095Lithocholic AcidLithocholic Acid results in increased phosphorylation of and results in decreased activity of GSK3B protein20512997
C115354lonafarnib[Bortezomib co-treated with lonafarnib] results in decreased expression of GSK3B protein modified form16118318
D019808LosartanLosartan inhibits the reaction [AGT protein modified form results in increased phosphorylation of GSK3B protein]22982863
D008148LovastatinLovastatin results in decreased phosphorylation of GSK3B protein17234346
D008148LovastatinLovastatin results in increased phosphorylation of GSK3B protein19741129
C010480lupeollupeol binds to GSK3B protein18222664
C008301lysophosphatidylethanolamine[lysophosphatidylethanolamine analog co-treated with cobaltous chloride] results in increased phosphorylation of GSK3B protein25125499
D008274MagnesiumMagnesium affects the reaction [Lithium results in decreased activity of GSK3B protein]10998351
D058185Magnetite NanoparticlesMagnetite Nanoparticles results in decreased expression of GSK3B mRNA24525745
D058185Magnetite Nanoparticles[Succimer binds to Magnetite Nanoparticles] which results in decreased expression of GSK3B mRNA21641980
D058185Magnetite Nanoparticles[Succimer co-treated with Magnetite Nanoparticles] affects the expression of GSK3B mRNA26378955
D008294MalathionMalathion results in increased expression of GSK3B mRNA25449180
D008298MaleatesMaleates results in decreased phosphorylation of GSK3B protein21976531
C065861malvidin"malvidin promotes the reaction [[endotoxin, Escherichia coli results in increased phosphorylation of and results in increased activity of AKT1 protein] which results in increased phosphorylation of GSK3B protein]"23755222
C013099mancozeb[alachlor co-treated with Captan co-treated with Diazinon co-treated with Endosulfan co-treated with mancozeb co-treated with Maneb] affects the phosphorylation of GSK3B protein19883720
D008344Maneb[alachlor co-treated with Captan co-treated with Diazinon co-treated with Endosulfan co-treated with mancozeb co-treated with Maneb] affects the phosphorylation of GSK3B protein19883720
C025340manganese chloride2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [manganese chloride results in decreased phosphorylation of GSK3B protein]20937724
C025340manganese chloride2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [manganese chloride results in increased activity of GSK3B protein]20937724
C025340manganese chlorideGSK3B protein affects the reaction [manganese chloride results in increased phosphorylation of MAPT protein]20937724
C025340manganese chlorideLithium Chloride inhibits the reaction [manganese chloride results in decreased phosphorylation of and results in increased activity of GSK3B protein]24464479
C025340manganese chloride[Lithium Chloride results in decreased activity of GSK3B protein] inhibits the reaction [manganese chloride results in increased phosphorylation of MAPT protein]20937724
C025340manganese chloridemanganese chloride results in decreased phosphorylation of and results in increased activity of GSK3B protein24464479
C025340manganese chloridemanganese chloride results in decreased phosphorylation of GSK3B protein20937724
C025340manganese chloridemanganese chloride results in increased activity of GSK3B protein20937724
C078290manzamine Amanzamine A results in decreased activity of GSK3B protein22050263
D008550MelatoninMelatonin inhibits the reaction [wortmannin results in decreased expression of GSK3B protein modified form]15842767
D008627Mercuric ChlorideGSK3B protein promotes the reaction [Mercuric Chloride results in increased activity of BAX protein]22785175
D008627Mercuric ChlorideGSK3B protein promotes the reaction [Mercuric Chloride results in increased cleavage of CASP3 protein]22785175
D008687MetforminMetformin results in increased phosphorylation of GSK3B protein21054339
D008701MethapyrileneMethapyrilene results in increased expression of GSK3B mRNA16393664
D008715Methionine[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of GSK3B gene20938992
D008727MethotrexateMethotrexate promotes the reaction [6-bromoindirubin-3'-oxime results in increased phosphorylation of GSK3B protein]19727391
C445068methyl 2-cyano-3,12-dioxoolean-1,9-dien-28-oate"GSK3B protein mutant form inhibits the reaction [methyl 2-cyano-3,12-dioxoolean-1,9-dien-28-oate results in increased expression of HMOX1 protein]"25246272
C445068methyl 2-cyano-3,12-dioxoolean-1,9-dien-28-oate"GSK3B protein mutant form inhibits the reaction [methyl 2-cyano-3,12-dioxoolean-1,9-dien-28-oate results in increased phosphorylation of GSK3B protein]"25246272
C445068methyl 2-cyano-3,12-dioxoolean-1,9-dien-28-oate"methyl 2-cyano-3,12-dioxoolean-1,9-dien-28-oate results in increased phosphorylation of GSK3B protein"25246272
C004925methylmercuric chloridemethylmercuric chloride results in decreased expression of GSK3B mRNA28001369
C004925methylmercuric chloridemethylmercuric chloride results in increased expression of GSK3B mRNA28001369
C004925methylmercuric chloridemethylmercuric chloride results in increased expression of GSK3B mRNA20061341
C004925methylmercuric chloridemethylmercuric chloride results in decreased phosphorylation of and results in increased activity of GSK3B protein28821999
C004925methylmercuric chloridemethylmercuric chloride results in decreased phosphorylation of GSK3B protein29258870
C004925methylmercuric chloridemethylmercuric chloride results in increased phosphorylation of GSK3B protein28736149
D008741Methyl MethanesulfonateMethyl Methanesulfonate results in increased expression of GSK3B mRNA23649840
D018817N-Methyl-3,4-methylenedioxyamphetamine"N-Methyl-3,4-methylenedioxyamphetamine results in increased expression of GSK3B mRNA"19285098|2018815
D018817N-Methyl-3,4-methylenedioxyamphetamine"N-Methyl-3,4-methylenedioxyamphetamine results in increased expression of GSK3B protein"19285098
D008770Methylnitrosourea[Methylnitrosourea co-treated with Testosterone] results in decreased expression of GSK3B protein25164625
D008770MethylnitrosoureaQuercetin inhibits the reaction [[Methylnitrosourea co-treated with Testosterone] results in decreased expression of GSK3B protein]25164625
D0156551-Methyl-4-phenylpyridinium2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [IGF1 protein promotes the reaction [1-Methyl-4-phenylpyridinium results in increased phosphorylation of GSK3B protein]]20064577
D0156551-Methyl-4-phenylpyridiniumIGF1 protein promotes the reaction [1-Methyl-4-phenylpyridinium results in increased phosphorylation of GSK3B protein]20064577
D0156551-Methyl-4-phenylpyridinium1-Methyl-4-phenylpyridinium results in decreased phosphorylation of GSK3B protein22891246
D0156551-Methyl-4-phenylpyridinium1-Methyl-4-phenylpyridinium results in increased phosphorylation of and results in decreased activity of GSK3B protein26048653
D0156551-Methyl-4-phenylpyridinium1-Methyl-4-phenylpyridinium results in increased phosphorylation of GSK3B protein20064577
D0156551-Methyl-4-phenylpyridinium2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased phosphorylation of GSK3B protein]20064577
D0156551-Methyl-4-phenylpyridinium2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Ecdysterone inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased phosphorylation of and results in decreased activity of GSK3B protein]]26048653
D0156551-Methyl-4-phenylpyridiniumEcdysterone inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased phosphorylation of and results in decreased activity of GSK3B protein]26048653
D0156321-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine"1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased phosphorylation of GSK3B protein"22891246|2391187
D0156321-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine"2,3,5,4'-tetrahydroxystilbene 2-O-glucopyranoside inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased phosphorylation of GSK3B protein]"23911879
D0156321-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine"bis(3)-cognitin inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased phosphorylation of GSK3B protein]"22891246
C008493methylselenic acidmethylselenic acid inhibits the reaction [Doxorubicin results in increased phosphorylation of GSK3B protein]17339365
C008493methylselenic acidmethylselenic acid results in decreased phosphorylation of GSK3B protein17339365
D008777MethyltestosteroneMethyltestosterone results in decreased expression of GSK3B mRNA29191790
D015735MifepristoneMifepristone inhibits the reaction [Progesterone results in increased phosphorylation of GSK3B protein]16882987
D008911MinocyclineMinocycline results in increased phosphorylation of GSK3B protein15569265
C010052mizoribinemizoribine inhibits the reaction [Puromycin Aminonucleoside results in increased phosphorylation of GSK3B protein]20502051
C016599mono-(2-ethylhexyl)phthalatemono-(2-ethylhexyl)phthalate inhibits the reaction [INS1 protein results in increased phosphorylation of GSK3B protein]28526321
C008542monodansylcadaverinemonodansylcadaverine results in decreased expression of GSK3B protein16170020
C517284monomethyl phthalatemonomethyl phthalate affects the expression of GSK3B mRNA26924002
C008548morinmorin inhibits the reaction [Acetaminophen results in decreased phosphorylation of GSK3B protein]26767949
C008548morinmorin inhibits the reaction [Diethylnitrosamine results in increased expression of GSK3B protein modified form]19931519
D009020MorphineMorphine results in increased expression of GSK3B protein modified form20600172
D009020MorphineNaloxone inhibits the reaction [Morphine results in increased expression of GSK3B protein modified form]20600172
D009020MorphineGSK3B protein results in decreased activity of Morphine19966058
D009020MorphineMorphine results in increased phosphorylation of GSK3B protein19966058
D009020Morphine"N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [Morphine results in increased phosphorylation of GSK3B protein]"19966058
D009173Mycophenolic AcidMycophenolic Acid inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of GSK3B protein]20302854
C063509N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamideN-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Caffeine results in increased phosphorylation of GSK3B protein]21229324
C479831N-(4-methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea"N-(4-methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea inhibits the reaction [Okadaic Acid results in increased expression of GSK3B protein]"21715663
C479831N-(4-methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea"N-(4-methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea inhibits the reaction [Okadaic Acid results in increased expression of GSK3B protein modified form]"21715663
C479831N-(4-methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea"[N-(4-methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea results in decreased activity of GSK3B protein] inhibits the reaction [Okadaic Acid results in increased phosphorylation of MAPT protein]"21715663
C479831N-(4-methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea"[N-(4-methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea results in decreased activity of GSK3B protein] results in increased susceptibility to [troglitazone results in decreased expression of CCNB1 protein]"20540935
C479831N-(4-methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea"[N-(4-methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea results in decreased activity of GSK3B protein] results in increased susceptibility to [troglitazone results in decreased expression of CCND1 protein]"20540935
C479831N-(4-methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea"[N-(4-methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea results in decreased activity of GSK3B protein] results in increased susceptibility to [troglitazone results in decreased expression of CCNE1 protein]"20540935
C479831N-(4-methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea"[N-(4-methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea results in decreased activity of GSK3B protein] results in increased susceptibility to [troglitazone results in decreased expression of CDK2 protein]"20540935
C479831N-(4-methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea"[N-(4-methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea results in decreased activity of GSK3B protein] results in increased susceptibility to [troglitazone results in decreased expression of CDK4 protein]"20540935
C479831N-(4-methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea"[N-(4-methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea results in decreased activity of GSK3B protein] results in increased susceptibility to [troglitazone results in increased expression of BAX protein]"20540935
C479831N-(4-methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea"[N-(4-methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea results in decreased activity of GSK3B protein] results in increased susceptibility to [troglitazone results in increased expression of CASP3 protein]"20540935
C479831N-(4-methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea"[N-(4-methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea results in decreased activity of GSK3B protein] results in increased susceptibility to [troglitazone results in increased expression of CASP9 protein]"20540935
C479831N-(4-methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea"[N-(4-methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea results in decreased activity of GSK3B protein] which results in decreased susceptibility to Okadaic Acid"21715663
C479831N-(4-methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea"[N-(4-methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea results in decreased activity of GSK3B protein] which results in decreased susceptibility to Proadifen"22683934
C479831N-(4-methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea"[N-(4-methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea results in decreased activity of GSK3B protein] which results in increased susceptibility to troglitazone"20540935
C479831N-(4-methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea"N-(4-methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea results in decreased activity of GSK3B protein"16202587
C479831N-(4-methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea"N-(4-methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea results in decreased activity of GSK3B protein"20540935|2171566
C064769N-acetylsphingosineGSK3B mutant form inhibits the reaction [N-acetylsphingosine results in increased expression of LGALS3 protein]21821001
C064769N-acetylsphingosineN-acetylsphingosine results in decreased phosphorylation of GSK3B protein21821001
D009270NaloxoneNaloxone inhibits the reaction [Morphine results in increased expression of GSK3B protein modified form]20600172
D037742Nanotubes, Carbon"Nanotubes, Carbon affects the expression of GSK3B mRNA"23845593
D037742Nanotubes, Carbon"Nanotubes, Carbon analog results in decreased expression of GSK3B mRNA"25554681
C000621033napabucasinnapabucasin results in decreased expression of GSK3B mRNA25605917
D009288NaproxenNaproxen results in decreased activity of GSK3B protein23784744
C524653nectandrin-Bnectandrin-B results in increased phosphorylation of GSK3B protein27511913
C524653nectandrin-BGSK3B protein inhibits the reaction [nectandrin-B results in increased expression of GCLC mRNA]27511913
C524653nectandrin-BGSK3B protein inhibits the reaction [nectandrin-B results in increased expression of GCLC protein]27511913
D009355Neomycin2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Neomycin results in increased phosphorylation of GSK3B protein]15800129
D009355NeomycinNeomycin results in increased phosphorylation of GSK3B protein15800129
C022838nickel chloridenickel chloride promotes the reaction [Tretinoin results in increased phosphorylation of GSK3B protein]25614230
C022838nickel chloride[nickel chloride results in increased phosphorylation of AKT1 protein] which results in decreased activity of and results in increased phosphorylation of GSK3B protein21837363
C022838nickel chloridenickel chloride affects the expression of GSK3B mRNA22546817
C029938nickel sulfatenickel sulfate results in increased expression of GSK3B mRNA17374397
D009534NiclosamideNiclosamide results in decreased expression of GSK3B mRNA22576131
D009538Nicotine[Nicotine results in increased phosphorylation of and results in increased activity of AKT1 protein] which results in increased phosphorylation of GSK3B protein12511591
C012655nimesulidenimesulide results in decreased activity of GSK3B protein16331303
D009583NitrofurazoneNitrofurazone binds to GSK3B protein18222664
C562238N-methyl-3-(1-(4-(piperazin-1-yl)phenyl)-5-(4'-(trifluoromethyl)-(1,1'-biphenyl)-4-yl)-1H-pyrazol-3-yl)propanamide"ILK protein inhibits the reaction [N-methyl-3-(1-(4-(piperazin-1-yl)phenyl)-5-(4'-(trifluoromethyl)-(1,1'-biphenyl)-4-yl)-1H-pyrazol-3-yl)propanamide results in decreased phosphorylation of GSK3B protein]"21823616
C562238N-methyl-3-(1-(4-(piperazin-1-yl)phenyl)-5-(4'-(trifluoromethyl)-(1,1'-biphenyl)-4-yl)-1H-pyrazol-3-yl)propanamide"N-methyl-3-(1-(4-(piperazin-1-yl)phenyl)-5-(4'-(trifluoromethyl)-(1,1'-biphenyl)-4-yl)-1H-pyrazol-3-yl)propanamide results in decreased phosphorylation of GSK3B protein"21823616
C044387N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine"N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [Morphine results in increased phosphorylation of GSK3B protein]"19966058
C072936notoginsenoside R1fulvestrant inhibits the reaction [notoginsenoside R1 inhibits the reaction [Lipopolysaccharides results in decreased expression of GSK3B protein modified form]]23170834
C072936notoginsenoside R1notoginsenoside R1 inhibits the reaction [Lipopolysaccharides results in decreased expression of GSK3B protein modified form]23170834
C072936notoginsenoside R1wortmannin inhibits the reaction [notoginsenoside R1 inhibits the reaction [Lipopolysaccharides results in decreased expression of GSK3B protein modified form]]23170834
C072936notoginsenoside R1notoginsenoside R1 results in increased expression of GSK3B protein modified form24720662
C404397NSC 680410NSC 680410 results in decreased phosphorylation of GSK3B protein14647418
C558013NSC 689534[NSC 689534 binds to Copper] which results in increased expression of GSK3B mRNA20971185
C025589ochratoxin Aochratoxin A results in increased phosphorylation of GSK3B protein25002221
D019319Okadaic Acid[5-iodo-3-(2-azetidinylmethoxy)pyridine binds to and results in increased activity of CHRNB2 protein] inhibits the reaction [Okadaic Acid results in increased expression of GSK3B protein]21715663
D019319Okadaic Acid[5-iodo-3-(2-azetidinylmethoxy)pyridine binds to and results in increased activity of CHRNB2 protein] inhibits the reaction [Okadaic Acid results in increased expression of GSK3B protein modified form]21715663
D019319Okadaic Acid"N-(4-methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea inhibits the reaction [Okadaic Acid results in increased expression of GSK3B protein]"21715663
D019319Okadaic Acid"N-(4-methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea inhibits the reaction [Okadaic Acid results in increased expression of GSK3B protein modified form]"21715663
D019319Okadaic Acid"[N-(4-methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea results in decreased activity of GSK3B protein] inhibits the reaction [Okadaic Acid results in increased phosphorylation of MAPT protein]"21715663
D019319Okadaic Acid"[N-(4-methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea results in decreased activity of GSK3B protein] which results in decreased susceptibility to Okadaic Acid"21715663
D019319Okadaic AcidOkadaic Acid inhibits the reaction [resveratrol results in decreased phosphorylation of GSK3B protein]23292070
D019319Okadaic AcidOkadaic Acid results in increased expression of GSK3B protein21715663
D019319Okadaic AcidOkadaic Acid results in increased expression of GSK3B protein modified form21715663
D019319Okadaic Acid[PNU-282987 binds to and results in increased activity of CHRNA7 protein] inhibits the reaction [Okadaic Acid results in increased expression of GSK3B protein]21715663
D019319Okadaic Acid[PNU-282987 binds to and results in increased activity of CHRNA7 protein] inhibits the reaction [Okadaic Acid results in increased expression of GSK3B protein modified form]21715663
D019319Okadaic Acid2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Quercetin inhibits the reaction [Okadaic Acid affects the phosphorylation of GSK3B protein]]27050422
D019319Okadaic AcidLithium Chloride inhibits the reaction [Okadaic Acid affects the phosphorylation of GSK3B protein]27050422
D019319Okadaic AcidOkadaic Acid affects the phosphorylation of GSK3B protein27050422
D019319Okadaic AcidQuercetin inhibits the reaction [Okadaic Acid affects the phosphorylation of GSK3B protein]27050422
C076029olanzapineolanzapine results in increased phosphorylation of GSK3B protein19440698
D009942Organometallic CompoundsOrganometallic Compounds results in decreased activity of GSK3B protein17210701
C030110oxaliplatin[oxaliplatin co-treated with Topotecan] results in decreased expression of GSK3B mRNA25729387
D010100Oxygencobaltiprotoporphyrin promotes the reaction [Oxygen deficiency results in increased phosphorylation of GSK3B protein]24658657
D010100Oxygen[Oxygen deficiency co-treated with Blood Glucose deficiency] results in decreased phosphorylation of GSK3B protein24058562
D010100OxygenOxygen deficiency results in increased phosphorylation of GSK3B protein24658657
D010100Oxygensodium bisulfide inhibits the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in decreased phosphorylation of GSK3B protein]24058562
D010100Oxygentin protoporphyrin IX inhibits the reaction [cobaltiprotoporphyrin promotes the reaction [Oxygen deficiency results in increased phosphorylation of GSK3B protein]]24658657
D000073878Palm OilPalm Oil results in decreased expression of GSK3B mRNA18042831
D010269Paraquat6-bromoindirubin-3'-oxime promotes the reaction [Paraquat inhibits the reaction [TNFRSF10B protein binds to GSK3B protein]]28414160
D010269Paraquat6-bromoindirubin-3'-oxime promotes the reaction [Paraquat results in decreased expression of GSK3B protein modified form]28414160
D010269ParaquatParaquat inhibits the reaction [TNFRSF10B protein binds to GSK3B protein]28414160
D010269ParaquatParaquat results in decreased expression of GSK3B protein28414160
D010269ParaquatParaquat results in increased expression of and results in increased phosphorylation of GSK3B protein22292029
D010269ParaquatParaquat results in increased phosphorylation of GSK3B protein24634145
D052638Particulate MatterParticulate Matter results in decreased expression of GSK3B mRNA28412507
C522391perfluorododecanoic acidGSK3B protein affects the susceptibility to perfluorododecanoic acid23353032
C522391perfluorododecanoic acidperfluorododecanoic acid results in decreased expression of GSK3B protein23353032
C522391perfluorododecanoic acidperfluorododecanoic acid results in decreased expression of GSK3B protein modified form23353032
C101816perfluoro-n-nonanoic acidperfluoro-n-nonanoic acid results in increased expression of GSK3B protein modified form22387981
C076994perfluorooctane sulfonic acidLithium Chloride inhibits the reaction [perfluorooctane sulfonic acid results in decreased phosphorylation of GSK3B protein]27018151
C076994perfluorooctane sulfonic acidperfluorooctane sulfonic acid results in decreased phosphorylation of GSK3B protein27018151
C023036perfluorooctanoic acidperfluorooctanoic acid results in increased phosphorylation of GSK3B protein28947262
C027579periodate-oxidized adenosineperiodate-oxidized adenosine affects the expression of GSK3B mRNA17097637
D015232DinoprostoneDinoprostone results in increased phosphorylation of GSK3B protein18395713
D015232DinoprostoneDinoprostone results in increased phosphorylation of GSK3B protein20578217
C058305phenethyl isothiocyanateAcetylcysteine inhibits the reaction [phenethyl isothiocyanate results in increased phosphorylation of GSK3B protein]25246272
C058305phenethyl isothiocyanatephenethyl isothiocyanate results in increased phosphorylation of GSK3B protein25246272
D010634PhenobarbitalPhenobarbital results in decreased expression of GSK3B mRNA23091169
D010656PhenylephrineGRK2 protein affects the reaction [Phenylephrine results in increased phosphorylation of GSK3B protein]28759639
D010656PhenylephrinePhenylephrine results in increased phosphorylation of GSK3B protein15795328|2875963
D010656PhenylephrineSGK1 protein promotes the reaction [Phenylephrine results in increased phosphorylation of GSK3B protein]15795328
D010693PhloretinPhloretin results in decreased activity of GSK3B protein16968061
D010696PhloroglucinolPhloroglucinol analog results in decreased phosphorylation of GSK3B protein23178381
D010743PhospholipidsPhospholipids results in increased phosphorylation of GSK3B protein15956784
D064209PhytochemicalsPhytochemicals results in decreased phosphorylation of GSK3B protein22685690
D048789Phytoestrogens2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Phytoestrogens results in increased phosphorylation of GSK3B protein]24726523
D048789Phytoestrogensfulvestrant inhibits the reaction [Phytoestrogens results in increased phosphorylation of GSK3B protein]24726523
D048789PhytoestrogensPhytoestrogens results in increased phosphorylation of GSK3B protein24726523
C544307PI 620PI 620 results in decreased phosphorylation of GSK3B protein19584227
D010936Plant ExtractsPlant Extracts results in decreased phosphorylation of GSK3B protein22685690
D010936Plant ExtractsPlant Extracts results in decreased activity of GSK3B protein24380755
D010936Plant ExtractsPlant Extracts inhibits the reaction [Streptozocin results in increased expression of GSK3B mRNA]27038876
C498513PNU-282987[PNU-282987 binds to and results in increased activity of CHRNA7 protein] inhibits the reaction [Okadaic Acid results in increased expression of GSK3B protein]21715663
C498513PNU-282987[PNU-282987 binds to and results in increased activity of CHRNA7 protein] inhibits the reaction [Okadaic Acid results in increased expression of GSK3B protein modified form]21715663
C498513PNU-282987[PNU-282987 binds to and results in increased activity of CHRNA7 protein] which results in increased phosphorylation of GSK3B protein21715663
D011078Polychlorinated Biphenyls2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Polychlorinated Biphenyls analog results in decreased expression of GSK3B protein]24361488
D011078Polychlorinated BiphenylsPolychlorinated Biphenyls analog results in decreased expression of GSK3B protein24361488
D011188PotassiumPotassium results in increased phosphorylation of and results in decreased activity of GSK3B protein15950778
C027373potassium chromate(VI)[potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of GSK3B mRNA22079256
C027373potassium chromate(VI)potassium chromate(VI) results in decreased expression of GSK3B mRNA22079256
D011280PregnanolonePregnanolone results in decreased expression of GSK3B protein17443805
D011335ProadifenGSK3B protein affects the susceptibility to Proadifen22683934
D011335Proadifen"[N-(4-methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea results in decreased activity of GSK3B protein] which results in decreased susceptibility to Proadifen"22683934
C479580procyanidin B2procyanidin B2 inhibits the reaction [MFGE8 protein results in decreased expression of GSK3B protein modified form]21505870
C479580procyanidin B2procyanidin B2 results in increased expression of GSK3B protein modified form21505870
D011374ProgesteroneMifepristone inhibits the reaction [Progesterone results in increased phosphorylation of GSK3B protein]16882987
D011374ProgesteroneProgesterone results in increased phosphorylation of GSK3B protein16882987
D011374ProgesteroneProgesterone inhibits the reaction [Estradiol results in increased phosphorylation of GSK3B protein]15845746
D011374ProgesteroneEstradiol inhibits the reaction [Progesterone results in decreased expression of GSK3B mRNA]17170212
D011374ProgesteroneProgesterone results in decreased expression of GSK3B mRNA17170212
D011374ProgesteroneProgesterone results in decreased expression of GSK3B protein17443805
D011374ProgesteroneProgesterone results in decreased phosphorylation of GSK3B protein17443805
D011433PropranololPropranolol results in decreased phosphorylation of GSK3B protein22982863
C107773pterostilbenepterostilbene inhibits the reaction [Azoxymethane results in increased phosphorylation of GSK3B protein]20681671
D011692Puromycin Aminonucleosidemizoribine inhibits the reaction [Puromycin Aminonucleoside results in increased phosphorylation of GSK3B protein]20502051
D011692Puromycin AminonucleosidePuromycin Aminonucleoside results in increased phosphorylation of GSK3B protein20502051
C014175pyrazolo(3,4-d)pyrimidine"pyrazolo(3,4-d)pyrimidine analog affects the expression of GSK3B mRNA"21152443
C014175pyrazolo(3,4-d)pyrimidine"pyrazolo(3,4-d)pyrimidine analog affects the expression of GSK3B mRNA"21152443
C008704pyrithioneAKT1 protein promotes the reaction [[Zinc co-treated with pyrithione] results in increased phosphorylation of and results in increased activity of GSK3B protein]17098228
C008704pyrithioneGSK3B protein promotes the reaction [[Zinc co-treated with pyrithione] results in increased phosphorylation of MAPT protein]17098228
C008704pyrithione[Zinc co-treated with pyrithione] results in increased phosphorylation of and results in increased activity of GSK3B protein17098228
C020972pyrrolidine dithiocarbamic acidpyrrolidine dithiocarbamic acid results in increased phosphorylation of GSK3B protein17409235
D011794QuercetinQuercetin promotes the reaction [arctigenin results in decreased phosphorylation of GSK3B protein]25380086
D011794QuercetinQuercetin results in decreased activity of GSK3B protein16968061
D011794QuercetinQuercetin results in decreased expression of GSK3B mRNA23727915
D011794QuercetinQuercetin results in decreased expression of GSK3B protein16968065
D011794Quercetin2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Quercetin inhibits the reaction [Okadaic Acid affects the phosphorylation of GSK3B protein]]27050422
D011794QuercetinQuercetin inhibits the reaction [Dietary Fats results in increased expression of GSK3B mRNA]27260466
D011794QuercetinQuercetin inhibits the reaction [Okadaic Acid affects the phosphorylation of GSK3B protein]27050422
D011794QuercetinQuercetin inhibits the reaction [[Methylnitrosourea co-treated with Testosterone] results in decreased expression of GSK3B protein]25164625
D011794QuercetinQuercetin inhibits the reaction [[Warfarin co-treated with Vitamin K] results in increased phosphorylation of GSK3B protein]23117658
D011796QuinacrineGSK3B protein affects the reaction [Quinacrine results in decreased expression of CCND1 protein]28720477
D011796QuinacrineGSK3B protein affects the reaction [Quinacrine results in decreased expression of CTNNB1 protein]28720477
D011796QuinacrineGSK3B protein affects the reaction [Quinacrine results in decreased expression of GLI1 protein]28720477
D011796QuinacrineGSK3B protein affects the reaction [Quinacrine results in decreased expression of MYC protein]28720477
D011796QuinacrineGSK3B protein affects the reaction [Quinacrine results in increased activity of CASP3 protein]28720477
D011796QuinacrineGSK3B protein affects the reaction [Quinacrine results in increased expression of CSNK1A1 protein]28720477
D011796QuinacrineQuinacrine results in increased expression of and results in decreased phosphorylation of GSK3B protein28720477
D011796QuinacrineQuinacrine results in increased expression of GSK3B mRNA28720477
C502851quinocetoneLithium Chloride promotes the reaction [quinocetone affects the phosphorylation of and results in decreased activity of GSK3B protein]28343033
C502851quinocetonequinocetone affects the phosphorylation of and results in decreased activity of GSK3B protein28343033
C052785rebamipiderebamipide results in increased expression of GSK3B mRNA18299717
C059514resveratrol2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [resveratrol results in increased phosphorylation of and results in increased activity of GSK3B protein]20696143
C059514resveratrol2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one promotes the reaction [resveratrol results in decreased phosphorylation of and results in decreased activity of GSK3B protein]20696143
C059514resveratrol2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [resveratrol results in increased phosphorylation of and results in increased activity of GSK3B protein]20696143
C059514resveratrol2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [resveratrol results in increased phosphorylation of GSK3B protein]14750165
C059514resveratrol2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one promotes the reaction [resveratrol results in decreased phosphorylation of and results in decreased activity of GSK3B protein]20696143
C059514resveratrol"(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine inhibits the reaction [resveratrol results in decreased activity of GSK3B protein]"19620254
C059514resveratrol"(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine inhibits the reaction [resveratrol results in increased phosphorylation of GSK3B protein]"19620254
C059514resveratrolARRB2 protein affects the reaction [resveratrol results in decreased expression of GSK3B protein modified form]20457218
C059514resveratrolGSK3B protein affects the reaction [resveratrol results in increased expression of FTH1 mRNA]23829535
C059514resveratrolOkadaic Acid inhibits the reaction [resveratrol results in decreased phosphorylation of GSK3B protein]23292070
C059514resveratrolresveratrol affects the expression of GSK3B protein modified form22234583
C059514resveratrolresveratrol inhibits the reaction [Excitatory Amino Acid Agonists affects the phosphorylation of GSK3B protein]24675465
C059514resveratrolresveratrol inhibits the reaction [GSK3B protein binds to SIRT1 protein]23292070
C059514resveratrolresveratrol inhibits the reaction [MFGE8 protein results in decreased expression of GSK3B protein modified form]21505870
C059514resveratrolresveratrol results in decreased activity of GSK3B protein19620254
C059514resveratrolresveratrol results in decreased expression of GSK3B protein modified form20133117|2045721
C059514resveratrolresveratrol results in decreased phosphorylation of and results in decreased activity of GSK3B protein20696143
C059514resveratrol[resveratrol results in decreased phosphorylation of and results in decreased activity of GSK3B protein] which results in increased phosphorylation of and results in decreased localization of CTNNB1 protein20696143
C059514resveratrolresveratrol results in decreased phosphorylation of GSK3B protein14750165|2009093
C059514resveratrol[resveratrol results in decreased phosphorylation of GSK3B protein] which results in decreased expression of HSF1 mRNA20090934
C059514resveratrol[resveratrol results in decreased phosphorylation of GSK3B protein] which results in decreased expression of HSPA1A protein20090934
C059514resveratrolresveratrol results in increased activity of GSK3B protein17868649|2009093
C059514resveratrol[resveratrol results in increased activity of GSK3B protein] which results in decreased expression of HSF1 mRNA20090934
C059514resveratrolresveratrol results in increased expression of GSK3B protein modified form21505870
C059514resveratrolresveratrol results in increased phosphorylation of and results in increased activity of GSK3B protein20696143
C059514resveratrol[resveratrol results in increased phosphorylation of and results in increased activity of GSK3B protein] which results in decreased phosphorylation of and results in increased localization of CTNNB1 protein20696143
C059514resveratrolresveratrol results in increased phosphorylation of GSK3B protein14750165|1962025
C059514resveratrol2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [resveratrol results in increased phosphorylation of and results in decreased activity of GSK3B protein]20542495
C059514resveratrol"(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine inhibits the reaction [[resveratrol results in increased phosphorylation of GSK3B protein] which results in increased uptake of Glucose]"22180358
C059514resveratrolresveratrol affects the phosphorylation of GSK3B protein24254769
C059514resveratrol[resveratrol co-treated with Excitatory Amino Acid Agents] results in increased phosphorylation of and results in decreased activity of GSK3B protein20542495
C059514resveratrolresveratrol inhibits the reaction [Dietary Fats results in increased expression of GSK3B mRNA]24812660|2726046
C059514resveratrolresveratrol results in decreased activity of GSK3B protein19665018
C059514resveratrolresveratrol results in decreased expression of GSK3B protein19665018
C059514resveratrolresveratrol results in increased phosphorylation of and results in decreased activity of GSK3B protein20542495
C059514resveratrolresveratrol results in increased phosphorylation of GSK3B protein19665018|2218035
C059514resveratrol[resveratrol results in increased phosphorylation of GSK3B protein] which results in increased uptake of Glucose22180358
C059514resveratrol"1H-(1,2,4)oxadiazolo(4,3-a)quinoxalin-1-one inhibits the reaction [resveratrol results in increased activity of GSK3B protein]"19135050
C059514resveratrolresveratrol inhibits the reaction [APP protein modified form results in decreased expression of GSK3B protein modified form]25654502
C059514resveratrolresveratrol inhibits the reaction [Excitatory Amino Acid Agonists affects the phosphorylation of GSK3B protein]24675465
C059514resveratrolresveratrol results in decreased phosphorylation of GSK3B protein24675465
C059514resveratrol[resveratrol results in increased activity of GSK3B protein] which results in increased phosphorylation of VASP protein19135050
C059514resveratrolresveratrol results in increased phosphorylation of and results in decreased activity of GSK3B protein16860989
C059514resveratrolresveratrol results in increased phosphorylation of and results in increased localization of and results in increased activity of GSK3B protein19135050
C059514resveratrolresveratrol results in increased phosphorylation of GSK3B protein22857612
D018967RisperidoneDRD2 protein affects the reaction [Risperidone results in increased expression of GSK3B protein]16144542
D018967RisperidoneRisperidone results in increased expression of GSK3B protein16144542
C064758Ro 31-8220Ro 31-8220 results in decreased activity of GSK3B protein10998351
C089730rosiglitazonerosiglitazone results in increased phosphorylation of GSK3B protein25796170
C089730rosiglitazonerosiglitazone results in decreased activity of GSK3B protein19621015
C089730rosiglitazonerosiglitazone results in increased phosphorylation of GSK3B protein19566839
C089730rosiglitazonewortmannin inhibits the reaction [rosiglitazone results in increased phosphorylation of GSK3B protein]19566839
C089730rosiglitazoneGSK3B affects the reaction [rosiglitazone inhibits the reaction [TNF protein results in increased activity of MMP9 protein]]19201691
C089730rosiglitazoneGSK3B protein mutant form affects the reaction [rosiglitazone inhibits the reaction [TNF protein affects the localization of RELA protein]]19201691
C089730rosiglitazonerosiglitazone affects the reaction [PDGFB protein results in increased phosphorylation of GSK3B protein]19201691
D012402Rotenone"1,3-dihydro-1-(1-((4-(6-phenyl-1H-imidazo(4,5-g)quinoxalin-7-yl)phenyl)methyl)-4-piperidinyl)-2H-benzimidazol-2-one inhibits the reaction [Bibenzyls inhibits the reaction [Rotenone results in decreased phosphorylation of GSK3B protein]]"28245986
D012402RotenoneBibenzyls inhibits the reaction [Rotenone results in decreased phosphorylation of GSK3B protein]28245986
D012402RotenonePARK7 protein affects the reaction [Bibenzyls inhibits the reaction [Rotenone results in decreased phosphorylation of GSK3B protein]]28245986
D012402RotenoneRotenone results in decreased phosphorylation of GSK3B protein28245986
D012402RotenoneRotenone affects the expression of GSK3B mRNA23186747
D012402Rotenone"1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid inhibits the reaction [Rotenone results in decreased phosphorylation of GSK3B protein]"25433145
D012402Rotenone"1,3-dihydro-1-(1-((4-(6-phenyl-1H-imidazo(4,5-g)quinoxalin-7-yl)phenyl)methyl)-4-piperidinyl)-2H-benzimidazol-2-one inhibits the reaction [Bibenzyls inhibits the reaction [Rotenone results in decreased phosphorylation of GSK3B protein]]"28245986
D012402RotenoneBibenzyls inhibits the reaction [Rotenone results in decreased phosphorylation of GSK3B protein]28245986
D012402RotenonePARK7 protein affects the reaction [Bibenzyls inhibits the reaction [Rotenone results in decreased phosphorylation of GSK3B protein]]28245986
D012402RotenoneRotenone results in decreased phosphorylation of GSK3B protein25433145|2824598
C085746rottlerin[Cadmium co-treated with rottlerin] results in decreased expression of GSK3B protein27658547
C085746rottlerinrottlerin inhibits the reaction [Cadmium results in increased phosphorylation of GSK3B protein]27658547
C085746rottlerinrottlerin results in decreased expression of GSK3B protein27658547
C046245rubimaillinrubimaillin results in increased phosphorylation of GSK3B protein23466342
D012428RutheniumRuthenium results in decreased activity of GSK3B protein17210701
D017975Ruthenium CompoundsRuthenium Compounds results in decreased activity of GSK3B protein16858717|1721070
C010327salinomycinsalinomycin results in decreased expression of GSK3B mRNA19682730
C036617salsolinolsalsolinol results in decreased phosphorylation of GSK3B protein23261589
C093642SB 203580SB 203580 inhibits the reaction [DEFA1 protein results in increased phosphorylation of GSK3B protein]19814765
C093642SB 203580SB 203580 inhibits the reaction [DEFA2 protein results in increased phosphorylation of GSK3B protein]19814765
C093642SB 203580SB 203580 results in decreased activity of GSK3B protein10998351
C417521SB 216763SB 216763 results in decreased activity of GSK3B protein19486905
C417521SB 216763PIK3CA protein affects the reaction [SB 216763 results in increased phosphorylation of and results in decreased activity of GSK3B protein]19196980
C417521SB 216763SB 216763 inhibits the reaction [cinobufagin results in increased expression of GSK3B protein modified form]23164673
C417521SB 216763SB 216763 results in decreased activity of GSK3B protein19823589
C417521SB 216763[SB 216763 results in decreased activity of GSK3B protein] inhibits the reaction [Sirolimus results in decreased expression of CCND1 protein]15753396
C417521SB 216763[SB 216763 results in decreased activity of GSK3B protein] results in decreased susceptibility to [Arachidonic Acid co-treated with Iron]19620254
C417521SB 216763[SB 216763 results in decreased activity of GSK3B protein] which results in increased expression of HSPA1A protein alternative form20090934
C417521SB 216763SB 216763 results in decreased phosphorylation of and results in decreased activity of GSK3B protein21980429
C417521SB 216763SB 216763 results in decreased phosphorylation of GSK3B protein16170020
C417521SB 216763SB 216763 results in increased expression of and results in increased phosphorylation of and results in decreased activity of GSK3B protein19196980
C417521SB 216763SB 216763 results in decreased activity of GSK3B protein19159680
C417521SB 216763[SB 216763 results in decreased activity of GSK3B protein] which results in increased expression of CTNNB1 protein19159680
C417521SB 216763SB 216763 results in decreased phosphorylation of GSK3B protein19448134
C417521SB 216763SB 216763 inhibits the reaction [Excitatory Amino Acid Agonists affects the phosphorylation of GSK3B protein]24675465
C417521SB 216763SB 216763 results in decreased activity of GSK3B protein16288908
C417521SB 216763SB 216763 binds to and results in decreased activity of GSK3B protein15958644
C417521SB 216763SB 216763 results in decreased activity of GSK3B protein15979805|1721070
D012643Selenium[Selenium co-treated with Vitamin E] results in increased expression of GSK3B mRNA19244175
D012643SeleniumSelenium inhibits the reaction [Doxorubicin results in increased phosphorylation of GSK3B protein]17339365
D012643SeleniumSelenium results in decreased expression of GSK3B mRNA19244175
D012643SeleniumSelenium results in decreased phosphorylation of GSK3B protein17339365
D017632Asbestos, Serpentine"1,3-dihydro-1-(1-((4-(6-phenyl-1H-imidazo(4,5-g)quinoxalin-7-yl)phenyl)methyl)-4-piperidinyl)-2H-benzimidazol-2-one analog inhibits the reaction [Asbestos, Serpentine results in increased phosphorylation of GSK3B protein]"26685284
D017632Asbestos, Serpentine"Asbestos, Serpentine results in increased phosphorylation of GSK3B protein"26685284
D012715Sesame OilSesame Oil results in increased expression of GSK3B mRNA29191790
C042431S-ethyl glutathioneS-ethyl glutathione inhibits the reaction [Fenretinide results in increased phosphorylation of GSK3B protein]25246272
C042431S-ethyl glutathioneS-ethyl glutathione results in increased phosphorylation of GSK3B protein25246272
C009250sevofluraneLithium Chloride inhibits the reaction [sevoflurane results in decreased phosphorylation of GSK3B protein]20807582
C009250sevofluranesevoflurane results in decreased phosphorylation of GSK3B protein20807582
C040115shogaolshogaol results in increased expression of and results in increased phosphorylation of GSK3B protein27645308
D012822Silicon DioxideSilicon Dioxide analog results in decreased phosphorylation of GSK3B protein24831964
D012822Silicon DioxideSilicon Dioxide analog results in decreased phosphorylation of GSK3B protein24831964
D012834SilverSilver results in increased expression of GSK3B mRNA29283201
D012834SilverSilver affects the phosphorylation of GSK3B protein27593553
D019821SimvastatinSimvastatin results in increased expression of GSK3B19461118
D019821SimvastatinSimvastatin inhibits the reaction [Glucose results in decreased phosphorylation of and results in increased activity of GSK3B protein]18004065
D019821SimvastatinSimvastatin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of GSK3B protein]18047562
D019821SimvastatinSimvastatin results in increased expression of GSK3B protein modified form18004065
D020123Sirolimus[Sirolimus results in decreased activity of MTOR protein] which results in increased phosphorylation of GSK3B protein17908691
D020123Sirolimus"[3-(3-chloro-4-hydroxyphenylamino)-4-(4-nitrophenyl)-1H-pyrrole-2,5-dione results in decreased activity of GSK3B protein] inhibits the reaction [Sirolimus results in decreased expression of CCND1 protein]"15753396
D020123Sirolimus[Lithium Chloride results in decreased activity of GSK3B protein] inhibits the reaction [Sirolimus results in decreased expression of CCND1 protein]15753396
D020123Sirolimus[SB 216763 results in decreased activity of GSK3B protein] inhibits the reaction [Sirolimus results in decreased expression of CCND1 protein]15753396
D020123Sirolimus[Sirolimus results in decreased activity of MTOR protein] which results in increased phosphorylation of GSK3B protein17908691
D020123SirolimusSirolimus results in increased activity of GSK3B protein15753396
D020123Sirolimus[Sirolimus results in increased activity of GSK3B protein] which results in increased phosphorylation of and results in increased degradation of CCND1 protein15753396
D020123SirolimusSirolimus inhibits the reaction [TSC1 gene mutant form results in decreased phosphorylation of GSK3B protein]18495876
C009277sodium arsenatesodium arsenate results in decreased expression of GSK3B mRNA21795629
C009277sodium arsenatesodium arsenate results in increased expression of GSK3B mRNA21795629
C017947sodium arsenitesodium arsenite affects the expression of GSK3B mRNA22058191
C017947sodium arsenite[Ethanol co-treated with sodium arsenite] results in increased phosphorylation of GSK3B protein26220687
C017947sodium arseniteLithium promotes the reaction [sodium arsenite results in increased phosphorylation of GSK3B protein]17849503
C017947sodium arsenite[sodium arsenite co-treated with Ethanol] results in increased phosphorylation of GSK3B protein22872060
C017947sodium arsenitesodium arsenite results in decreased phosphorylation of GSK3B protein20043101
C017947sodium arsenitesodium arsenite results in increased expression of GSK3B protein modified form16054901
C017947sodium arsenitesodium arsenite results in increased phosphorylation of and results in increased activity of GSK3B protein12614848
C017947sodium arsenitesodium arsenite results in increased phosphorylation of GSK3B protein17849503|2285922
C017947sodium arsenitewortmannin inhibits the reaction [sodium arsenite results in increased phosphorylation of and results in increased activity of GSK3B protein]12614848
C017947sodium arsenitesodium arsenite results in increased phosphorylation of GSK3B protein12529330
C016104sodium bichromatesodium bichromate results in decreased expression of GSK3B mRNA22155349
C025451sodium bisulfidesodium bisulfide inhibits the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in decreased phosphorylation of GSK3B protein]24058562
D012969Sodium FluorideDKK1 protein inhibits the reaction [Sodium Fluoride results in increased phosphorylation of GSK3B protein]24300170
D012969Sodium FluorideSodium Fluoride results in increased phosphorylation of GSK3B protein24300170
D018038Sodium SeleniteSodium Selenite results in decreased expression of GSK3B mRNA18175754
C471405sorafenibarsenic trioxide inhibits the reaction [sorafenib results in increased phosphorylation of GSK3B protein]25416439
C471405sorafenibGSK3B inhibits the reaction [sorafenib affects the localization of AIFM1 protein]17991738
C471405sorafenibGSK3B inhibits the reaction [sorafenib affects the localization of DIABLO protein]17991738
C471405sorafenibsorafenib inhibits the reaction [arsenic trioxide results in decreased phosphorylation of GSK3B protein]25416439
C471405sorafenibsorafenib promotes the reaction [GSK3B protein results in increased phosphorylation of MYC protein]17991738
C471405sorafenibsorafenib promotes the reaction [GSK3B protein results in increased phosphorylation of TP53 protein]17991738
C471405sorafenibsorafenib results in decreased phosphorylation of and results in increased activity of GSK3B protein17991738
C471405sorafenibsorafenib results in increased phosphorylation of GSK3B protein25416439
D013311StreptozocinCurcumin inhibits the reaction [Streptozocin results in decreased phosphorylation of GSK3B protein]25541178
D013311StreptozocinPlant Extracts inhibits the reaction [Streptozocin results in increased expression of GSK3B mRNA]27038876
D013311StreptozocinStreptozocin results in decreased phosphorylation of GSK3B protein25541178
D013311StreptozocinStreptozocin results in increased expression of GSK3B mRNA27038876
D004113Succimer[Succimer binds to Magnetite Nanoparticles] which results in decreased expression of GSK3B mRNA21641980
D004113Succimer[Succimer co-treated with Magnetite Nanoparticles] affects the expression of GSK3B mRNA26378955
D013467SulindacSulindac results in decreased phosphorylation of GSK3B protein11593435
D013605T-2 ToxinT-2 Toxin results in decreased expression of GSK3B mRNA26141394
D016559Tacrolimus[GSK3A protein co-treated with GSK3B protein] affects the reaction [Tacrolimus results in increased expression of SNAI1 protein]22416070
D016559TacrolimusTacrolimus results in increased phosphorylation of GSK3B protein22416070
C061133tamibarotenetamibarotene affects the expression of GSK3B mRNA15498508
D013629TamoxifenTamoxifen promotes the reaction [2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in decreased phosphorylation of GSK3B protein]22046442
D013629TamoxifenTamoxifen results in decreased phosphorylation of and results in increased expression of GSK3B protein23921149
C112765tanespimycintanespimycin results in decreased expression of GSK3B protein modified form20090934
C021751tanshinonetanshinone results in decreased expression of GSK3B mRNA25186638
D013655Taurochenodeoxycholic AcidTaurochenodeoxycholic Acid results in increased phosphorylation of and results in decreased activity of GSK3B protein20512997
D013739TestosteroneTestosterone results in increased expression of GSK3B mRNA21880219
D013739TestosteroneTestosterone results in increased expression of GSK3B mRNA20843997
D013739Testosterone[Methylnitrosourea co-treated with Testosterone] results in decreased expression of GSK3B protein25164625
D013739TestosteroneQuercetin inhibits the reaction [[Methylnitrosourea co-treated with Testosterone] results in decreased expression of GSK3B protein]25164625
C004648testosterone enanthatetestosterone enanthate affects the expression of GSK3B mRNA17440010
C020806tetrabromobisphenol Atetrabromobisphenol A results in decreased expression of GSK3B mRNA27914987
D013749TetrachlorodibenzodioxinCycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of GSK3B mRNA]11007951
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased expression of GSK3B mRNA11007951
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased phosphorylation of GSK3B protein27312872
D013749TetrachlorodibenzodioxinAHR protein inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of GSK3B mRNA]15034205
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of GSK3B mRNA15034205
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased phosphorylation of GSK3B protein18996433
D013749Tetrachlorodibenzodioxin2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Tetrachlorodibenzodioxin results in increased phosphorylation of GSK3B protein]24231000
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased phosphorylation of GSK3B protein23639626
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased phosphorylation of GSK3B protein24231000
D013755Tetradecanoylphorbol AcetateTetradecanoylphorbol Acetate results in increased phosphorylation of GSK3B protein17993264
D013755Tetradecanoylphorbol AcetateU 0126 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of GSK3B protein]17993264
C050950tetrakis(N-methyl-4-pyridiniumyl)porphine manganese(III) complextetrakis(N-methyl-4-pyridiniumyl)porphine manganese(III) complex inhibits the reaction [Ethanol results in increased phosphorylation of GSK3B protein]28962519
C009438tetrandrinetetrandrine results in decreased expression of GSK3B protein modified form25266202
D013792ThalidomideThalidomide results in increased expression of GSK3B mRNA19751816
D008063Thioctic AcidThioctic Acid inhibits the reaction [Dietary Fats results in increased expression of GSK3B mRNA]27260466
D008063Thioctic AcidThioctic Acid results in increased phosphorylation of GSK3B protein19879292
D013882Thiosemicarbazones[Copper binds to Thiosemicarbazones analog] which results in decreased activity of GSK3B protein19122148
D013882Thiosemicarbazones[Thiosemicarbazones binds to Copper] which results in increased expression of GSK3B protein20931265
D013893ThiramThiram results in decreased expression of GSK3B mRNA20530235
C032628tin protoporphyrin IXtin protoporphyrin IX inhibits the reaction [cobaltiprotoporphyrin promotes the reaction [Oxygen deficiency results in increased phosphorylation of GSK3B protein]]24658657
D014028Tobacco Smoke PollutionGSK3B protein inhibits the reaction [Tobacco Smoke Pollution results in increased activity of [CTNNB1 protein binds to TCF4 protein]]19429245
D014028Tobacco Smoke PollutionTobacco Smoke Pollution results in decreased expression of GSK3B protein19429245
D014028Tobacco Smoke PollutionTobacco Smoke Pollution results in increased phosphorylation of and results in decreased activity of GSK3B protein19429245
D014051Toluene 2,4-Diisocyanate"2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Toluene 2,4-Diisocyanate results in increased phosphorylation of GSK3B protein]"26089345
D014051Toluene 2,4-Diisocyanate"Toluene 2,4-Diisocyanate results in increased phosphorylation of GSK3B protein"26089345
D019772Topotecan[oxaliplatin co-treated with Topotecan] results in decreased expression of GSK3B mRNA25729387
D014118Toxins, Biological"Toxins, Biological affects the expression of GSK3B mRNA"19682533
D014212TretinoinTretinoin results in increased expression of GSK3B mRNA20530235
D014212Tretinoinnickel chloride promotes the reaction [Tretinoin results in increased phosphorylation of GSK3B protein]25614230
D014212TretinoinTretinoin affects the expression of GSK3B mRNA15498508
D014212TretinoinTretinoin results in increased phosphorylation of GSK3B protein25614230
D014212TretinoinTretinoin results in decreased phosphorylation of GSK3B protein16288212
D014212TretinoinTretinoin results in increased phosphorylation of GSK3B protein16288212
C057693troglitazoneGSK3B protein affects the susceptibility to troglitazone20540935
C057693troglitazoneGSK3B protein affects the susceptibility to [troglitazone results in decreased expression of CCNB1 protein]20540935
C057693troglitazoneGSK3B protein affects the susceptibility to [troglitazone results in decreased expression of CCND1 protein]20540935
C057693troglitazoneGSK3B protein affects the susceptibility to [troglitazone results in decreased expression of CCNE1 protein]20540935
C057693troglitazoneGSK3B protein affects the susceptibility to [troglitazone results in decreased expression of CDK2 protein]20540935
C057693troglitazoneGSK3B protein affects the susceptibility to [troglitazone results in decreased expression of CDK4 protein]20540935
C057693troglitazoneGSK3B protein affects the susceptibility to [troglitazone results in increased expression of BAX protein]20540935
C057693troglitazoneGSK3B protein affects the susceptibility to [troglitazone results in increased expression of CASP3 protein]20540935
C057693troglitazoneGSK3B protein affects the susceptibility to [troglitazone results in increased expression of CASP9 protein]20540935
C057693troglitazone"[N-(4-methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea results in decreased activity of GSK3B protein] results in increased susceptibility to [troglitazone results in decreased expression of CCNB1 protein]"20540935
C057693troglitazone"[N-(4-methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea results in decreased activity of GSK3B protein] results in increased susceptibility to [troglitazone results in decreased expression of CCND1 protein]"20540935
C057693troglitazone"[N-(4-methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea results in decreased activity of GSK3B protein] results in increased susceptibility to [troglitazone results in decreased expression of CCNE1 protein]"20540935
C057693troglitazone"[N-(4-methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea results in decreased activity of GSK3B protein] results in increased susceptibility to [troglitazone results in decreased expression of CDK2 protein]"20540935
C057693troglitazone"[N-(4-methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea results in decreased activity of GSK3B protein] results in increased susceptibility to [troglitazone results in decreased expression of CDK4 protein]"20540935
C057693troglitazone"[N-(4-methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea results in decreased activity of GSK3B protein] results in increased susceptibility to [troglitazone results in increased expression of BAX protein]"20540935
C057693troglitazone"[N-(4-methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea results in decreased activity of GSK3B protein] results in increased susceptibility to [troglitazone results in increased expression of CASP3 protein]"20540935
C057693troglitazone"[N-(4-methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea results in decreased activity of GSK3B protein] results in increased susceptibility to [troglitazone results in increased expression of CASP9 protein]"20540935
C057693troglitazone"[N-(4-methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea results in decreased activity of GSK3B protein] which results in increased susceptibility to troglitazone"20540935
C057693troglitazonetroglitazone results in decreased activity of GSK3B protein20540935
C113580U 0126U 0126 inhibits the reaction [arsenic trioxide results in increased phosphorylation of GSK3B protein]21278055
C113580U 0126U 0126 inhibits the reaction [Fenretinide results in increased phosphorylation of GSK3B protein]25246272
C113580U 0126U 0126 inhibits the reaction [EDN1 protein results in increased phosphorylation of GSK3B protein]17993264
C113580U 0126U 0126 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of GSK3B protein]17993264
D014520UrethaneUrethane results in increased expression of GSK3B mRNA28818685
D014635Valproic Acid"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of GSK3B mRNA"27188386
D014635Valproic AcidValproic Acid affects the expression of GSK3B mRNA25979313
D014635Valproic AcidValproic Acid results in decreased activity of GSK3B protein19101580
D014635Valproic AcidValproic Acid results in decreased expression of GSK3B mRNA26272509
D014635Valproic AcidValproic Acid results in increased phosphorylation of and results in decreased activity of GSK3B protein19328817
D014635Valproic AcidValproic Acid results in increased phosphorylation of GSK3B protein19440698
D014635Valproic Acid"4-benzyl-2-methyl-1,2,4-thiadiazolidine-3,5-dione promotes the reaction [Valproic Acid inhibits the reaction [Kainic Acid results in decreased phosphorylation of GSK3B protein]]"25453207
D014635Valproic AcidValproic Acid inhibits the reaction [Kainic Acid results in decreased phosphorylation of GSK3B protein]25453207
D014635Valproic AcidValproic Acid results in decreased expression of GSK3B mRNA19359144
D001335Vehicle EmissionsVehicle Emissions results in decreased methylation of GSK3B gene25560391
C025643vinclozolinvinclozolin affects the expression of GSK3B mRNA19015723
D014752Vinyl ChlorideVinyl Chloride metabolite results in increased expression of GSK3B mRNA26962056
D012256RiboflavinRiboflavin analog results in increased phosphorylation of GSK3B protein20688149
D012256RiboflavinRiboflavin results in increased phosphorylation of GSK3B protein20688149
D014810Vitamin E[Selenium co-treated with Vitamin E] results in increased expression of GSK3B mRNA19244175
D014810Vitamin EVitamin E results in decreased expression of GSK3B mRNA19244175
D014810Vitamin EVitamin E inhibits the reaction [wortmannin results in decreased expression of GSK3B protein modified form]15842767
D014812Vitamin KQuercetin inhibits the reaction [[Warfarin co-treated with Vitamin K] results in increased phosphorylation of GSK3B protein]23117658
D014812Vitamin K[Warfarin co-treated with Vitamin K] results in increased phosphorylation of GSK3B protein23117658
D014859WarfarinQuercetin inhibits the reaction [[Warfarin co-treated with Vitamin K] results in increased phosphorylation of GSK3B protein]23117658
D014859Warfarin[Warfarin co-treated with Vitamin K] results in increased phosphorylation of GSK3B protein23117658
C085514wogoninwogonin results in decreased expression of GSK3B protein modified form23872260
C085514wogoninwogonin results in decreased expression of GSK3B protein modified form23872260
C085514wogoninwogonin results in increased expression of GSK3B protein23872260
C009687wortmanninwortmannin inhibits the reaction [Estradiol results in increased phosphorylation of GSK3B protein]16076840
C009687wortmanninwortmannin inhibits the reaction [sodium arsenite results in increased phosphorylation of and results in increased activity of GSK3B protein]12614848
C009687wortmanninwortmannin inhibits the reaction [Zinc results in increased phosphorylation of GSK3B protein]17513037
C009687wortmanninwortmannin results in decreased phosphorylation of GSK3B protein20090934|2317838
C009687wortmanninMelatonin inhibits the reaction [wortmannin results in decreased expression of GSK3B protein modified form]15842767
C009687wortmanninVitamin E inhibits the reaction [wortmannin results in decreased expression of GSK3B protein modified form]15842767
C009687wortmanninwortmannin inhibits the reaction [notoginsenoside R1 inhibits the reaction [Lipopolysaccharides results in decreased expression of GSK3B protein modified form]]23170834
C009687wortmanninwortmannin results in decreased expression of GSK3B protein modified form15842767
C009687wortmanninwortmannin inhibits the reaction [chaetoglobosins results in increased phosphorylation of GSK3B protein]18040759
C009687wortmanninwortmannin inhibits the reaction [GRK2 protein results in increased phosphorylation of GSK3B protein]28759639
C009687wortmanninwortmannin inhibits the reaction [rosiglitazone results in increased phosphorylation of GSK3B protein]19566839
D015032Zinc2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Zinc results in increased phosphorylation of GSK3B protein]17513037
D015032Zincwortmannin inhibits the reaction [Zinc results in increased phosphorylation of GSK3B protein]17513037
D015032ZincZinc results in increased phosphorylation of GSK3B protein17513037
D015032ZincAKT1 protein promotes the reaction [[Zinc co-treated with pyrithione] results in increased phosphorylation of and results in increased activity of GSK3B protein]17098228
D015032ZincGSK3B protein promotes the reaction [[Zinc co-treated with pyrithione] results in increased phosphorylation of MAPT protein]17098228
D015032Zinc[Zinc co-treated with pyrithione] results in increased phosphorylation of and results in increased activity of GSK3B protein17098228
D015032ZincZinc deficiency results in decreased phosphorylation of GSK3B protein21893222

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0001085RNA polymerase II transcription factor binding-IPI20864106  
GO:0002020protease binding-IPI25118933  
GO:0002039p53 binding-IDA14744935  
GO:0004672protein kinase activity-TAS22988876  24115276  26049140  
GO:0004674protein serine/threonine kinase activity-IDA8638126  9072970  11035810  11104755  11955436  14744935  
16315267  17139249  18348280  
GO:0004674protein serine/threonine kinase activity-ISS-  
GO:0004674protein serine/threonine kinase activity-NAS8725894  28386764  
GO:0004674protein serine/threonine kinase activity-TAS-  
GO:0005515protein binding-IPI8638126  9482734  9601641  9731200  10481074  11004522  
11035810  11738041  12421363  12434148  12927815  14744935  
15147888  15448698  15752768  16198352  16282323  16365045  
16890161  17078951  17139249  17317006  17318191  17353931  
17510365  17601533  18045539  18505846  19131971  19202075  
19249679  19303846  19411070  19706605  19759537  20007971  
20080667  20368287  20389281  20856200  21118991  21217772  
21242974  21743491  21900206  21985244  21988832  22470507  
22682247  22699938  22773187  23010592  23455922  23602568  
24165324  24391509  24976009  25241761  25897075  25920809  
26496610  27484798  29568061  
GO:0005524ATP binding-IEA-  
GO:0008013beta-catenin binding-IPI8638126  
GO:0016301kinase activity-IDA15448698  24391509  
GO:0016301kinase activity-TAS-  
GO:0019901protein kinase binding-IPI18348280  
GO:0031625ubiquitin protein ligase binding-IPI21118991  
GO:0034236protein kinase A catalytic subunit binding-IPI11035810  
GO:0034452dynactin binding-IPI17139249  
GO:0050321tau-protein kinase activity-IDA14690523  16365045  
GO:0051059NF-kappaB binding-IPI15465828  
GO ID GO Term Qualifier Evidence PubMed
GO:0001837epithelial to mesenchymal transition-IMP15448698  
GO:0001954positive regulation of cell-matrix adhesion-IMP18156211  
GO:0005977glycogen metabolic process-IDA8638126  
GO:0006468protein phosphorylation-IDA11035810  16315267  20937854  
GO:0006468protein phosphorylation-TAS26049140  
GO:0006983ER overload response-IDA14744935  
GO:0007212dopamine receptor signaling pathway-NAS21711983  
GO:0007623circadian rhythm-ISS-  
GO:0010628positive regulation of gene expression-ISS-  
GO:0010822positive regulation of mitochondrion organization-IMP25118933  
GO:0016055Wnt signaling pathway-TAS-  
GO:0018105peptidyl-serine phosphorylation-IDA8638126  11104755  11955436  14744935  17139249  
GO:0018107peptidyl-threonine phosphorylation-IDA11955436  17139249  25897075  
GO:0021766hippocampus development-IMP19581563  
GO:0030010establishment of cell polarity-ISS-  
GO:0030010establishment of cell polarity-TAS18268107  
GO:0030011maintenance of cell polarity-ISS-  
GO:0030011maintenance of cell polarity-TAS18268107  
GO:0030516regulation of axon extension-ISS-  
GO:0031175neuron projection development-IDA19830702  
GO:0031333negative regulation of protein complex assembly-IMP16188939  
GO:0031334positive regulation of protein complex assembly-IDA8638126  
GO:0032091negative regulation of protein binding-IDA16890161  
GO:0032092positive regulation of protein binding-ISS-  
GO:0032436positive regulation of proteasomal ubiquitin-dependent protein catabolic process-IC11955436  
GO:0032436positive regulation of proteasomal ubiquitin-dependent protein catabolic process-IMP25897075  
GO:0032515negative regulation of phosphoprotein phosphatase activity-TAS28386764  
GO:0032886regulation of microtubule-based process-IMP20937854  
GO:0035556intracellular signal transduction-IDA14749367  
GO:0035556intracellular signal transduction-TAS26049140  
GO:0036016cellular response to interleukin-3-ISS-  
GO:0043066negative regulation of apoptotic process-IDA14744935  
GO:0043547positive regulation of GTPase activity-IMP18156211  
GO:0045719negative regulation of glycogen biosynthetic process-TAS19366350  
GO:0045732positive regulation of protein catabolic process-IC16188939  
GO:0046777protein autophosphorylation-IDA23184662  
GO:0046827positive regulation of protein export from nucleus-IDA14744935  
GO:0048814regulation of dendrite morphogenesis-ISS-  
GO:0050770regulation of axonogenesis-ISS-  
GO:0060070canonical Wnt signaling pathway-IC9601641  
GO:0060070canonical Wnt signaling pathway-IDA18787224  
GO:0060070canonical Wnt signaling pathway-TAS26049140  
GO:0060079excitatory postsynaptic potential-NAS21711983  
GO:0070507regulation of microtubule cytoskeleton organization-IMP17139249  
GO:0070507regulation of microtubule cytoskeleton organization-ISS-  
GO:0070885negative regulation of calcineurin-NFAT signaling cascade-IMP9072970  
GO:0071109superior temporal gyrus development-IMP19581563  
GO:0090090negative regulation of canonical Wnt signaling pathway-IC11955436  
GO:0090090negative regulation of canonical Wnt signaling pathway-TAS19366350  
GO:0097191extrinsic apoptotic signaling pathway-ISS-  
GO:0097192extrinsic apoptotic signaling pathway in absence of ligand-ISS-  
GO:0106028neuron projection retraction-ISS-  
GO:1900034regulation of cellular response to heat-TAS-  
GO:1900181negative regulation of protein localization to nucleus-ISS-  
GO:1901030positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway-ISS-  
GO:1901215negative regulation of neuron death-IDA19830702  
GO:1901216positive regulation of neuron death-IDA18508033  
GO:1901984negative regulation of protein acetylation-ISS-  
GO:1904339negative regulation of dopaminergic neuron differentiation-TAS24431302  
GO:1904646cellular response to amyloid-beta-ISS-  
GO:1904781positive regulation of protein localization to centrosome-IMP17139249  
GO:1904885beta-catenin destruction complex assembly-TAS-  
GO:1904886beta-catenin destruction complex disassembly-TAS-  
GO:2000077negative regulation of type B pancreatic cell development-TAS19366350  
GO:2000466negative regulation of glycogen (starch) synthase activity-TAS19366350  
GO ID GO Term Qualifier Evidence PubMed
GO:0005634nucleus-IDA14744935  15448698  
GO:0005654nucleoplasm-TAS-  
GO:0005737cytoplasm-IDA14744935  15448698  18787224  19038973  20937854  
GO:0005739mitochondrion-IEA-  
GO:0005813centrosome-IDA17139249  21399614  
GO:0005829cytosol-TAS-  
GO:0005886plasma membrane-IDA20937854  
GO:0030424axon-ISS-  
GO:0030425dendrite-ISS-  
GO:0030877beta-catenin destruction complex-IDA8638126  9601641  16188939  
GO:0030877beta-catenin destruction complex-TAS11955436  19366350  
GO:0098794postsynapse-IEA-  
GO:1990909Wnt signalosome-TAS24115276  
KEGG ID KEGG Term
hsa04012ErbB signaling pathway
hsa04062Chemokine signaling pathway
hsa04110Cell cycle
hsa04310Wnt signaling pathway
hsa04340Hedgehog signaling pathway
hsa04360Axon guidance
hsa04510Focal adhesion
hsa04660T cell receptor signaling pathway
hsa04662B cell receptor signaling pathway
hsa04722Neurotrophin signaling pathway
hsa04910Insulin signaling pathway
hsa04916Melanogenesis
hsa05010Alzheimer's disease
hsa05160Hepatitis C
hsa05200Pathways in cancer
hsa05210Colorectal cancer
hsa05213Endometrial cancer
hsa05215Prostate cancer
hsa05217Basal cell carcinoma
Reactome ID Reactome Term Evidence
R-HSA-1257604PIP3 activates AKT signalingIEA
R-HSA-1266738Developmental BiologyTAS
R-HSA-162582Signal TransductionTAS
R-HSA-162582Signal TransductionIEA
R-HSA-1640170Cell CycleIEA
R-HSA-1643685DiseaseTAS
R-HSA-195253Degradation of beta-catenin by the destruction complexTAS
R-HSA-195721Signaling by WNTTAS
R-HSA-195721Signaling by WNTIEA
R-HSA-196299Beta-catenin phosphorylation cascadeTAS
R-HSA-198323AKT phosphorylates targets in the cytosolIEA
R-HSA-201681TCF dependent signaling in response to WNTTAS
R-HSA-201681TCF dependent signaling in response to WNTIEA
R-HSA-212165Epigenetic regulation of gene expressionTAS
R-HSA-212436Generic Transcription PathwayIEA
R-HSA-2219528PI3K/AKT Signaling in CancerTAS
R-HSA-2262752Cellular responses to stressTAS
R-HSA-3371453Regulation of HSF1-mediated heat shock responseTAS
R-HSA-3371556Cellular response to heat stressTAS
R-HSA-373755Semaphorin interactionsTAS
R-HSA-399956CRMPs in Sema3A signalingTAS
R-HSA-422475Axon guidanceTAS
R-HSA-4641262Disassembly of the destruction complex and recruitment of AXIN to the membraneTAS
R-HSA-4641262Disassembly of the destruction complex and recruitment of AXIN to the membraneIEA
R-HSA-4791275Signaling by WNT in cancerTAS
R-HSA-4839735AXIN mutants destabilize the destruction complex, activating WNT signalingTAS
R-HSA-4839743phosphorylation site mutants of CTNNB1 are not targeted to the proteasome by the destruction complexTAS
R-HSA-4839744truncated APC mutants destabilize the destruction complexTAS
R-HSA-4839748AMER1 mutants destabilize the destruction complexTAS
R-HSA-5250913Positive epigenetic regulation of rRNA expressionTAS
R-HSA-5250924B-WICH complex positively regulates rRNA expressionTAS
R-HSA-5339716Misspliced GSK3beta mutants stabilize beta-cateninTAS
R-HSA-5358351Signaling by HedgehogTAS
R-HSA-5358351Signaling by HedgehogIEA
R-HSA-5358747S33 mutants of beta-catenin aren't phosphorylatedTAS
R-HSA-5358749S37 mutants of beta-catenin aren't phosphorylatedTAS
R-HSA-5358751S45 mutants of beta-catenin aren't phosphorylatedTAS
R-HSA-5358752T41 mutants of beta-catenin aren't phosphorylatedTAS
R-HSA-5467337APC truncation mutants have impaired AXIN bindingTAS
R-HSA-5467340AXIN missense mutants destabilize the destruction complexTAS
R-HSA-5467348Truncations of AMER1 destabilize the destruction complexTAS
R-HSA-5610783Degradation of GLI2 by the proteasomeIEA
R-HSA-5610785GLI3 is processed to GLI3R by the proteasomeTAS
R-HSA-5610787Hedgehog 'off' stateTAS
R-HSA-5610787Hedgehog 'off' stateIEA
R-HSA-5663202Diseases of signal transductionTAS
R-HSA-5674400Constitutive Signaling by AKT1 E17K in CancerTAS
R-HSA-69229Ubiquitin-dependent degradation of Cyclin D1IEA
R-HSA-69242S PhaseIEA
R-HSA-69278Cell Cycle, MitoticIEA
R-HSA-73857RNA Polymerase II TranscriptionIEA
R-HSA-74160Gene expression (Transcription)IEA
R-HSA-74160Gene expression (Transcription)TAS
R-HSA-75815Ubiquitin-dependent degradation of Cyclin DIEA
R-HSA-8878166Transcriptional regulation by RUNX2IEA
R-HSA-8939902Regulation of RUNX2 expression and activityIEA
R-HSA-8953897Cellular responses to external stimuliTAS
R-HSA-9006925Intracellular signaling by second messengersIEA

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
28592245In silico identification of potential key regulatory factors in smoking-induced lung cancer. (2017 Jun 7)El-Aarag SABMC Med Genomics
17727719Effect of active smoking on the human bronchial epithelium transcriptome. (2007 Aug 29)Chari RBMC Genomics
28296937Effects of circadian clock genes and health-related behavior on metabolic syndrome in a Taiwanese population: Evidence from association and interaction analysis. (2017)Lin EPLoS One
22413565[The relationship between glycogen synthase kinase-3 beta (GSK3B) -50T/C -1727A/T polymorphisms and alcoholism]. (2011 Dec)Yoshihara ENihon Arukoru Yakubutsu Igakkai Zasshi
25484085Autophagy and ethanol neurotoxicity. (2014)Luo JAutophagy