Gene: GSTM1

2944
GST1|GSTM1-1|GSTM1a-1a|GSTM1b-1b|GTH4|GTM1|H-B|MU|MU-1
glutathione S-transferase mu 1
protein-coding
1p13.3
Ensembl:ENSG00000134184 MIM:138350 Vega:OTTHUMG00000011635 UniprotKB:P09488
NG_009246.1
PubMed
ND|AD
750   
NA (AD)  NA (ND)   (Frontal_Cortex)
3.567e-1 (AD)  9.732e-1 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
GSTM30.293
SOX10.275
FAM171B0.272
MARC10.271
RASA4B0.271
GABRG10.269
SPDYE40.269
AKAP70.257
TBL1Y0.254
TMEM470.253

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
ARHGEF15-0.276
ACVRL1-0.264
GATA2-0.262
NOTCH4-0.259
THSD4-0.258
TNFRSF10C-0.256
LEF1-0.255
VWA2-0.254
VSTM1-0.254
ADCY4-0.253

Drugs/Compounds

ID Drug Name Drug Type CAS Num Status Role
DB00143GlutathioneSmall Molecule70-18-8Approved|Investigational|NutraceuticalTarget
DB01834(9R,10R)-9-(S-glutathionyl)-10-hydroxy-9,10-dihydrophenanthreneSmall MoleculeExperimentalTarget
DB02165Zinc TrihydroxideSmall MoleculeExperimentalTarget
DB02458S-(2,4-dinitrophenyl)glutathioneSmall Molecule26289-39-4ExperimentalTarget
DB03314FluorotryptophaneSmall Molecule16626-02-1ExperimentalTarget
DB04187(9S,10S)-9-(S-glutathionyl)-10-hydroxy-9,10-dihydrophenanthreneSmall MoleculeExperimentalTarget
DB00515CisplatinSmall Molecule15663-27-1ApprovedEnzyme
DB00526OxaliplatinSmall Molecule61825-94-3Approved|InvestigationalEnzyme
DB00958CarboplatinSmall Molecule41575-94-4ApprovedEnzyme
DB00993AzathioprineSmall Molecule446-86-6ApprovedEnzyme
DB01008BusulfanSmall Molecule55-98-1Approved|InvestigationalEnzyme
ID Drug Name Action PubMed
C0264861,2,5,6-dibenzanthracene"GSTM1 protein affects the metabolism of [1,2,5,6-dibenzanthracene co-treated with Glutathione]"9403173
C0122771,2-diamino-4-nitrobenzene"1,2-diamino-4-nitrobenzene results in increased expression of GSTM1 mRNA"17070881
C0283281,2-dichloro-4-nitrobenzene"GSTM1 protein affects the metabolism of 1,2-dichloro-4-nitrobenzene"1859377
C0283281,2-dichloro-4-nitrobenzene"GSTM1 protein affects the metabolism of 1,2-dichloro-4-nitrobenzene"7733673
C0493251,2-dithiol-3-thione"1,2-dithiol-3-thione results in increased expression of GSTM1 mRNA"18367636
C0493251,2-dithiol-3-thione"NFE2L2 gene mutant form inhibits the reaction [1,2-dithiol-3-thione results in increased expression of GSTM1 mRNA]"18367636
C0493251,2-dithiol-3-thione"1,2-dithiol-3-thione results in increased expression of GSTM1 mRNA"19162173|1969523
C0407561,2-naphthoquinone"GSTM1 protein results in decreased susceptibility to 1,2-naphthoquinone"10661898
C5768821-(2-trifluoromethoxyphenyl)-2-nitroethanone1-(2-trifluoromethoxyphenyl)-2-nitroethanone results in increased expression of GSTM1 protein22527513
C0317631,3-butadiene"GSTM1 gene polymorphism promotes the reaction [EPHX1 gene polymorphism results in increased susceptibility to 1,3-butadiene]"11238181
C0284741,4-bis(2-(3,5-dichloropyridyloxy))benzene"[1,4-bis(2-(3,5-dichloropyridyloxy))benzene results in increased activity of NR1I3 protein] which results in increased expression of GSTM1 mRNA"22496397
C0284741,4-bis(2-(3,5-dichloropyridyloxy))benzene"1,4-bis(2-(3,5-dichloropyridyloxy))benzene results in increased expression of GSTM1 mRNA"18723825|2249639
C0284741,4-bis(2-(3,5-dichloropyridyloxy))benzene"NR1I3 protein affects the reaction [1,4-bis(2-(3,5-dichloropyridyloxy))benzene results in increased expression of GSTM1 mRNA]"22496397
C09724015-deoxy-delta(12,14)-prostaglandin J2"GSTM1 protein affects the metabolism of [15-deoxy-delta(12,14)-prostaglandin J2 co-treated with Glutathione]"14979731
C0340861,5-naphthalenediamine"1,5-naphthalenediamine affects the expression of GSTM1 mRNA"17114358
C0152621,6-hexamethylene diisocyanate"GSTM1 protein polymorphism results in increased susceptibility to 1,6-hexamethylene diisocyanate"11927838
C0426301-chloro-2,4-dinitrobenzene-glutathione conjugate"GSTM1 protein affects the metabolism of 1-chloro-2,4-dinitrobenzene-glutathione conjugate"11684093
C0331461-hydroxypyreneGSTM1 gene polymorphism results in decreased secretion of 1-hydroxypyrene21787681
C0353141-nitropropane1-nitropropane results in decreased expression of GSTM1 mRNA17070881
C0142112,3,7,8-tetrachlorodibenzofuran"2,3,7,8-tetrachlorodibenzofuran affects the expression of GSTM1 mRNA"20702594
C0140242,4,5,2',4',5'-hexachlorobiphenyl"[2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Diethylnitrosamine] results in increased expression of GSTM1 protein"23457121
C0140242,4,5,2',4',5'-hexachlorobiphenyl"[Tetrachlorodibenzodioxin co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Diethylhexyl Phthalate co-treated with bisphenol A] results in decreased expression of GSTM1 mRNA"28433925
C0109142,4-diaminotoluene"2,4-diaminotoluene results in increased expression of GSTM1 mRNA"17070881
C0164032,4-dinitrotoluene"2,4-dinitrotoluene affects the expression of GSTM1 mRNA"21346803
C0859112-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in increased expression of GSTM1 mRNA22406437
C0094972-(4-toluidino)-6-naphthalenesulfonic acid2-(4-toluidino)-6-naphthalenesulfonic acid binds to GSTM1 protein7725348
C0252352,6-diaminotoluene"2,6-diaminotoluene results in decreased expression of GSTM1 mRNA"17070881
C0235142,6-dinitrotoluene"2,6-dinitrotoluene affects the expression of GSTM1 mRNA"21346803
C0993282-allylphenol2-allylphenol results in decreased activity of GSTM1 protein8620581
C0993282-allylphenol2-allylphenol results in decreased activity of GSTM1 protein8620581
C0495842-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine"GSTM1 gene polymorphism affects the susceptibility to 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine"22564066
C0369902-amino-3,8-dimethylimidazo(4,5-f)quinoxaline"GSTM1 gene polymorphism affects the susceptibility to 2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline"22564066
C0352082-amino-4,6-dinitrotoluene"2-amino-4,6-dinitrotoluene affects the expression of GSTM1 mRNA"21346803
C0605332-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine"2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of GSTM1 protein"17122891
C0147062-nitro-4-phenylenediamine2-nitro-4-phenylenediamine results in increased expression of GSTM1 mRNA17070881
C0166172-nitropropane2-nitropropane results in increased expression of GSTM1 mRNA17070881
C0823982-S-glutathionylcaffeic acid2-S-glutathionylcaffeic acid results in decreased activity of GSTM1 protein8340025
C0188552-tert-butylhydroquinone2-tert-butylhydroquinone results in increased expression of GSTM1 protein21443188
C0163923,3'-diindolylmethane"3,3'-diindolylmethane results in decreased expression of GSTM1 mRNA"19770484
C0163923,3'-diindolylmethane"[3,3'-diindolylmethane results in decreased expression of GSTM1 mRNA] which results in increased abundance of aflatoxin B1-DNA adduct"19770484
C0230353,4,5,3',4'-pentachlorobiphenyl"[3,4,5,3',4'-pentachlorobiphenyl co-treated with Sunphenon] affects the expression of GSTM1 mRNA"24378064
C0230353,4,5,3',4'-pentachlorobiphenyl"3,4,5,3',4'-pentachlorobiphenyl results in increased expression of GSTM1 mRNA"18723825
C0230353,4,5,3',4'-pentachlorobiphenyl"3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of GSTM1 mRNA"23196670
C0230353,4,5,3',4'-pentachlorobiphenyl"3,4,5,3',4'-pentachlorobiphenyl results in increased expression of GSTM1 mRNA"20959002
C0074303,4-dihydroxyphenylacetaldehyde"3,4-dihydroxyphenylacetaldehyde binds to GSTM1 protein"21238438
C0502243,5,5-trimethylhexanoylferrocene"3,5,5-trimethylhexanoylferrocene results in increased expression of GSTM1 protein"22649188
C0536033-methylpyridine3-methylpyridine results in decreased expression of GSTM1 protein7986210
C0095054,4'-diaminodiphenylmethane"4,4'-diaminodiphenylmethane results in decreased expression of GSTM1 mRNA"18648102
C0059694,4'-diphenylmethane diisocyanate"GSTM1 protein polymorphism results in increased susceptibility to 4,4'-diphenylmethane diisocyanate"11927838
C0286764-acetylaminofluorene4-acetylaminofluorene results in increased expression of GSTM1 mRNA17070881
C0352074-amino-2,6-dinitrotoluene"4-amino-2,6-dinitrotoluene affects the expression of GSTM1 mRNA"21346803
C0104074-chloronitrobenzeneGSTM1 protein affects the metabolism of [4-chloronitrobenzene analog co-treated with Glutathione]8867999
C0104074-chloronitrobenzeneGSTM1 protein affects the metabolism of [4-chloronitrobenzene analog co-treated with Glutathione]8973562
C0275764-hydroxy-2-nonenalGSTM1 protein affects the metabolism of 4-hydroxy-2-nonenal analog11256969
C0275764-hydroxy-2-nonenal[GSTM1 protein binds to GSTM2 protein] which affects the metabolism of 4-hydroxy-2-nonenal analog11256969
C0275764-hydroxy-2-nonenal[GSTM1 protein binds to GSTM3 protein] which affects the metabolism of 4-hydroxy-2-nonenal analog11256969
C0275764-hydroxy-2-nonenal4-hydroxy-2-nonenal results in increased expression of GSTM1 protein12020353
C0275764-hydroxy-2-nonenal[GSTM1 protein co-treated with 4-hydroxy-2-nonenal] results in decreased abundance of Glutathione21925487
C0275764-hydroxy-2-nonenal[GSTM1 protein co-treated with ABCC1 protein] results in increased susceptibility to 4-hydroxy-2-nonenal21925487
C0275764-hydroxy-2-nonenalGSTM1 protein affects the metabolism of 4-hydroxy-2-nonenal analog11256969
C0275764-hydroxy-2-nonenal[GSTM1 protein binds to GSTM2 protein] which affects the metabolism of 4-hydroxy-2-nonenal analog11256969
C5705404-O-decyl-gabosine D4-O-decyl-gabosine D inhibits the reaction [Glutathione binds to GSTM1 protein]22085405
C0022024-oxoretinoic acid4-oxoretinoic acid results in decreased expression of GSTM1 mRNA15982314
C0993274-propylphenol4-propylphenol results in decreased activity of GSTM1 protein8620581
C0993274-propylphenol4-propylphenol results in decreased activity of GSTM1 protein8620581
C0293704-toluidine4-toluidine results in increased expression of GSTM1 mRNA27638505
C5225895,6-dihydrocyclopenta-1,2-dithiole-3-thione"5,6-dihydrocyclopenta-1,2-dithiole-3-thione results in increased expression of GSTM1 mRNA"19695238
C5444715-hydroxythalidomide5-hydroxythalidomide binds to GSTM1 protein27464947
C5444715-hydroxythalidomide5-hydroxythalidomide binds to GSTM1 protein27464947
C0863965-S-glutathionyl-alpha-methyldopa5-S-glutathionyl-alpha-methyldopa results in decreased activity of GSTM1 protein8131222
C0863945-S-glutathionyldopamine5-S-glutathionyldopamine results in decreased activity of GSTM1 protein8131222
C0084507-methylguanineGSTM1 gene polymorphism affects the susceptibility to and affects the metabolism of 7-methylguanine15066569
C0371129-deoxy-delta-9-prostaglandin D2GSTM1 protein affects the metabolism of 9-deoxy-delta-9-prostaglandin D29084911
D000082AcetaminophenAcetaminophen results in decreased expression of GSTM1 mRNA29067470
D000082AcetaminophenGSTM1 protein inhibits the reaction [[CYP2E1 protein co-treated with CYP1A2 protein] results in increased susceptibility to Acetaminophen]28762043
D000082AcetaminophenAcetaminophen results in decreased expression of GSTM1 mRNA16611625
D000082Acetaminophen[CTH gene mutant form results in increased susceptibility to Acetaminophen] which results in decreased expression of GSTM1 protein25499718
D000082AcetaminophenGSTM1 gene mutant form inhibits the reaction [Acetaminophen results in increased phosphorylation of GSK3B protein]22687999
D000082AcetaminophenGSTM1 gene mutant form inhibits the reaction [Acetaminophen results in increased phosphorylation of MAP2K4 protein]22687999
D000082AcetaminophenGSTM1 results in increased susceptibility to Acetaminophen22687999
D000111AcetylcysteineAcetylcysteine inhibits the reaction [alpha-methylepinine results in increased expression of GSTM1 mRNA]21871945
D000111Acetylcysteine[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in increased expression of GSTM1 mRNA22129741
D020106Acrylamide[CYP2E1 gene polymorphism co-treated with GSTM1 gene polymorphism] affects the metabolism of Acrylamide19131562
D020106Acrylamide[CYP2E1 gene polymorphism co-treated with GSTM1 gene polymorphism co-treated with GSTT1 gene polymorphism] affects the metabolism of Acrylamide19131562
D020106AcrylamideGSTM1 gene polymorphism affects the metabolism of Acrylamide19131562|2140213
D020106Acrylamide[GSTM1 gene polymorphism affects the metabolism of Acrylamide] which affects the chemical synthesis of N-acetyl-S-(2-carbamoylethyl)cysteine21402133
D020106AcrylamideAcrylamide results in increased expression of GSTM1 mRNA27836571|2852632
D020106AcrylamideAcrylamide results in increased expression of GSTM1 protein28526328
D020106AcrylamideAcrylamide results in increased expression of GSTM1 mRNA28959563
C109238acylineacyline results in decreased expression of GSTM1 mRNA17510436
D016604Aflatoxin B1GSTM1 gene mutant form results in increased susceptibility to Aflatoxin B17892276
D016604Aflatoxin B1Aflatoxin B1 results in decreased expression of GSTM1 mRNA19770486
D016604Aflatoxin B1Aflatoxin B1 results in increased expression of GSTM1 mRNA23630614
C006426aflatoxin B1-2,3-oxide"GSTM1 protein affects the metabolism of and results in decreased activity of aflatoxin B1-2,3-oxide"1638515
C052669aflatoxin B1-bovine serum albuminGSTM1 gene mutant form results in increased abundance of aflatoxin B1-bovine serum albumin7892276
C072611aflatoxin B1-DNA adduct"[3,3'-diindolylmethane results in decreased expression of GSTM1 mRNA] which results in increased abundance of aflatoxin B1-DNA adduct"19770484
C072611aflatoxin B1-DNA adductGSTM1 gene polymorphism affects the abundance of aflatoxin B1-DNA adduct20442190
D000348AflatoxinsGSTM1 gene polymorphism results in increased susceptibility to Aflatoxins15734960
D000393Air PollutantsGSTM1 gene polymorphism affects the susceptibility to Air Pollutants22732554
D000395Air Pollutants, Occupational"GSTM1 gene polymorphism affects the susceptibility to Air Pollutants, Occupational"20723587
C103303alitretinoinalitretinoin results in decreased expression of GSTM1 mRNA15982314
C004471allyl isothiocyanateGSTM1 protein affects the metabolism of allyl isothiocyanate7826396
C038491allyl sulfideallyl sulfide results in increased expression of GSTM1 mRNA18723825
C038491allyl sulfideallyl sulfide results in increased expression of GSTM1 mRNA19695238|8627517
C038491allyl sulfideallyl sulfide results in increased expression of GSTM1 protein8627517
D000517alpha-Chlorohydrinalpha-Chlorohydrin analog results in increased expression of GSTM1 protein26597043
C069512alpha-methylepinineAcetylcysteine inhibits the reaction [alpha-methylepinine results in increased expression of GSTM1 mRNA]21871945
C069512alpha-methylepininealpha-methylepinine results in increased expression of GSTM1 mRNA21871945
C069512alpha-methylepininesulforafan inhibits the reaction [alpha-methylepinine results in increased expression of GSTM1 mRNA]21871945
D024502alpha-Tocopherol[alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of GSTM1 mRNA]22389237
C100057ametryneametryne results in increased expression of GSTM1 mRNA26310382
D000643Ammonium ChlorideAmmonium Chloride affects the expression of GSTM1 mRNA16483693
C019257angelica lactoneangelica lactone results in increased expression of GSTM1 protein11309284
C000228aristolochic acid Iaristolochic acid I results in increased expression of GSTM1 mRNA17483316
D001151ArsenicGSTM1 gene mutant form results in decreased susceptibility to Arsenic16353154
D001151ArsenicGSTM1 gene polymorphism affects the metabolism of and affects the susceptibility to Arsenic17365577
D001151ArsenicGSTM1 gene polymorphism affects the methylation of Arsenic25876999
D001151ArsenicGSTM1 polymorphism affects the metabolism of Arsenic17365577
D001151ArsenicGSTM1 protein affects the susceptibility to Arsenic18053222
D001151ArsenicGSTM1 mutant form affects the metabolism of Arsenic22136492
C006632arsenic trioxidearsenic trioxide results in increased expression of GSTM1 mRNA20458559|2252195
C006632arsenic trioxideGSTM1 protein results in decreased susceptibility to arsenic trioxide20067466
C015001arsenitearsenite results in increased expression of GSTM1 mRNA18929588
D001194AsbestosGSTM1 gene polymorphism affects the susceptibility to Asbestos20847076
D001194AsbestosGSTM1 gene polymorphism results in increased susceptibility to Asbestos18420450
D001205Ascorbic AcidGSTM1 affects the susceptibility to Ascorbic Acid deficiency19710200
D001205Ascorbic Acid"GSTM1 gene polymorphism affects the susceptibility to [Ascorbic Acid co-treated with tocotrienol, alpha]"15668500
D001205Ascorbic AcidAscorbic Acid inhibits the reaction [chromium hexavalent ion results in decreased expression of GSTM1 mRNA]23470461
D001205Ascorbic AcidAscorbic Acid inhibits the reaction [Potassium Dichromate results in decreased expression of GSTM1 mRNA]23470461
D001241AspirinGSTM1 mutant form affects the susceptibility to Aspirin16433794
D001280Atrazine[Atrazine co-treated with Chlorpyrifos co-treated with Endosulfan] results in increased expression of GSTM1 mRNA22515965
D001379AzathioprineGSTM1 gene polymorphism affects the susceptibility to Azathioprine17206640
D001379AzathioprineGSTM1 protein affects the metabolism of Azathioprine18155239|2043443
D001554BenzeneGSTM1 gene mutant form affects the susceptibility to Benzene14694614
D001554BenzeneGSTM1 gene polymorphism affects the reaction [GSTT1 gene polymorphism affects the reaction [NQO1 gene SNP results in increased susceptibility to Benzene]]17178637
D001554BenzeneGSTM1 gene polymorphism affects the susceptibility to Benzene15226677
D001554BenzeneGSTM1 gene polymorphism results in increased susceptibility to Benzene15226677|1574850
D001554BenzeneGSTM1 protein affects the metabolism of Benzene10511268|1522667
D001554Benzene[GSTM1 protein affects the metabolism of Benzene] which affects the abundance of muconic acid10511268
D001554BenzeneGSTM1 protein affects the susceptibility to Benzene29204680
D001554BenzeneGSTM1 protein results in increased metabolism of Benzene17885617
D001554BenzeneGSTM1 gene polymorphism affects the susceptibility to Benzene18848868
C023372benzene oxideGSTM1 protein affects the metabolism of benzene oxide22153878
C017228benzo(a)pyrene 7,8-dihydrodiol"GSTM1 protein inhibits the reaction [CYP1A1 protein promotes the reaction [benzo(a)pyrene 7,8-dihydrodiol results in increased mutagenesis of HPRT1 gene]]"17525473
C006703benzo(b)fluoranthene[Docosahexaenoic Acids co-treated with benzo(b)fluoranthene] results in decreased expression of GSTM1 protein25956473
D019324beta-Naphthoflavonebeta-Naphthoflavone results in increased expression of GSTM1 mRNA18723825
D019324beta-Naphthoflavonebeta-Naphthoflavone results in increased expression of GSTM1 mRNA22687991
D019324beta-Naphthoflavone[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of GSTM1 mRNA18164116|2004503
D019324beta-Naphthoflavoneisoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of GSTM1 mRNA]20045035
C105430benzofuranbenzofuran affects the expression of GSTM1 mRNA17114358
C089231benzo(g)chrysene-11,12-dihydrodiol-13,14-epoxide"GSTM1 protein results in increased glutathionylation of benzo(g)chrysene-11,12-dihydrodiol-13,14-epoxide"9308905
C022921benzo(k)fluoranthenebenzo(k)fluoranthene results in decreased expression of GSTM1 mRNA17253728
C022921benzo(k)fluoranthene[Docosahexaenoic Acids co-treated with benzo(k)fluoranthene] results in decreased expression of GSTM1 protein25956473
D001564Benzo(a)pyreneBenzo(a)pyrene results in decreased expression of GSTM1 mRNA17253728
D001564Benzo(a)pyrene[Docosahexaenoic Acids co-treated with Benzo(a)pyrene] results in decreased expression of GSTM1 protein25956473
D001564Benzo(a)pyreneGSTM1 gene polymorphism affects the susceptibility to Benzo(a)pyrene15471894
D001564Benzo(a)pyreneGSTM1 gene polymorphism results in increased susceptibility to Benzo(a)pyrene7728947
D001564Benzo(a)pyreneGSTM1 protein affects the metabolism of [Benzo(a)pyrene co-treated with Glutathione]9403173
D001564Benzo(a)pyreneGSTM1 protein inhibits the reaction [CYP1A1 protein promotes the reaction [Benzo(a)pyrene results in increased mutagenesis of HPRT1 gene]]17525473
D001564Benzo(a)pyreneGSTM1 protein inhibits the reaction [CYP1A1 protein results in increased susceptibility to Benzo(a)pyrene]17525473
D001564Benzo(a)pyreneGSTM1 protein polymorphism affects the metabolism of and affects the activity of Benzo(a)pyrene15298956
D001564Benzo(a)pyreneGSTM1 protein results in decreased susceptibility to Benzo(a)pyrene metabolite17525473
D001564Benzo(a)pyreneAHR protein promotes the reaction [Benzo(a)pyrene results in increased expression of GSTM1 mRNA]15034205
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of GSTM1 mRNA15034205|1977048
D001564Benzo(a)pyrene"[lipopolysaccharide, E coli O55-B5 co-treated with Benzo(a)pyrene] affects the expression of GSTM1 mRNA"28987381
D0151237,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide"7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased expression of GSTM1 mRNA"19150397
D0151237,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide"GSTM1 protein affects the metabolism of [7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide co-treated with Glutathione]"9403173
D0151237,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide"GSTM1 protein affects the metabolism of and results in decreased activity of [7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide co-treated with Glutathione]"11849043
C005465benzothiazolebenzothiazole results in increased expression of GSTM1 mRNA8951341
C012771benzotriazolebenzotriazole results in increased expression of GSTM1 mRNA8951341
C006710benzotriphenylenebenzotriphenylene results in decreased expression of GSTM1 mRNA17253728
D001583BenzoxazolesBenzoxazoles results in increased expression of GSTM1 mRNA8951341
C031403benzyl isothiocyanateGSTM1 protein affects the metabolism of benzyl isothiocyanate7826396
C072553benzyloxycarbonylleucyl-leucyl-leucine aldehydebenzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of GSTM1 mRNA20061341
C038328BEP protocolBEP protocol results in increased expression of GSTM1 mRNA18987330|2320077
D004958Estradiol[alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of GSTM1 mRNA]22389237
D004958EstradiolEstradiol affects the expression of GSTM1 mRNA22389237
C023888beta-hexachlorocyclohexaneGSTM1 gene polymorphism affects the susceptibility to beta-hexachlorocyclohexane22310945
D024503beta-Tocopherol[alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of GSTM1 mRNA]22389237
C099952bifenthrinbifenthrin results in increased expression of GSTM1 mRNA26071804
D001663BilirubinBilirubin results in decreased expression of GSTM1 mRNA20196124
C006780bisphenol AGSTM1 protein results in increased susceptibility to bisphenol A27491884
C006780bisphenol A"[Tetrachlorodibenzodioxin co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Diethylhexyl Phthalate co-treated with bisphenol A] results in decreased expression of GSTM1 mRNA"28433925
C006780bisphenol Abisphenol A affects the expression of GSTM1 mRNA25181051
C006780bisphenol Abisphenol A results in decreased expression of GSTM1 mRNA29097150
C006780bisphenol Abisphenol A results in increased expression of GSTM1 mRNA27208089
D001761BleomycinBleomycin results in decreased expression of GSTM1 protein25933445
C584056BMS-764459BMS-764459 results in increased expression of GSTM1 mRNA23831372
C032036bromobenzenebromobenzene metabolite binds to GSTM1 protein17305373
C032036bromobenzenebromobenzene results in increased expression of GSTM1 mRNA12628495
C026405bromotriethylstannanebromotriethylstannane inhibits the reaction [GSTM1 protein affects the metabolism of Dinitrochlorobenzene]7733673
C026405bromotriethylstannanebromotriethylstannane results in decreased activity of GSTM1 protein7733673
D002066BusulfanGSTM1 gene polymorphism affects the abundance of Busulfan20672371
D002066BusulfanGSTM1 gene polymorphism affects the susceptibility to Busulfan15142875|1958482
D002066Busulfan[GSTM1 gene polymorphism co-treated with GSTT1 gene polymorphism] affects the metabolism of Busulfan21215809
D002066BusulfanGSTM1 protein affects the metabolism of Busulfan8886613
D002066Busulfan[GSTM1 protein co-treated with CYP2C9 protein] results in increased susceptibility to [Busulfan co-treated with Cyclophosphamide]28744217
D019328Buthionine SulfoximineButhionine Sulfoximine results in increased expression of GSTM1 mRNA15878706
D002083Butylated HydroxyanisoleButylated Hydroxyanisole results in increased activity of GSTM1 protein11895860
D002083Butylated HydroxyanisoleButylated Hydroxyanisole results in increased expression of GSTM1 mRNA18723825
D002083Butylated HydroxyanisoleButylated Hydroxyanisole results in increased expression of GSTM1 protein11309284|1199180
D002083Butylated HydroxyanisoleNFE2L2 protein affects the reaction [Butylated Hydroxyanisole results in increased activity of GSTM1 protein]11895860
D002085ButylhydroxybutylnitrosamineButylhydroxybutylnitrosamine results in decreased expression of GSTM1 protein24998975
C018475butyraldehydebutyraldehyde results in increased expression of GSTM1 mRNA26079696
D020148Butyric AcidButyric Acid results in increased expression of GSTM1 mRNA12800193
D002101Cacodylic AcidCacodylic Acid results in increased expression of GSTM1 mRNA16436460
D002101Cacodylic AcidCacodylic Acid results in increased expression of GSTM1 protein16436460
D002104CadmiumCadmium results in increased expression of GSTM1 mRNA24067728
C028031cadmium acetatecadmium acetate affects the expression of GSTM1 mRNA16249259
D019256Cadmium ChlorideCadmium Chloride results in decreased expression of GSTM1 mRNA19031917
D019256Cadmium ChlorideCadmium Chloride results in decreased expression of GSTM1 mRNA25993096
C053400cafestol[cafestol co-treated with kahweol] results in increased expression of GSTM1 protein11346484
C053400cafestol[cafestol co-treated with kahweol palmitate] results in increased expression of GSTM1 protein11309284
C040048caffeic acidcaffeic acid results in decreased activity of GSTM1 protein8340025
D002185CannabidiolCannabidiol results in increased expression of GSTM1 mRNA21542829
D002220CarbamazepineGSTM1 gene mutant form results in increased susceptibility to Carbamazepine17465707
D002220CarbamazepineCarbamazepine results in increased expression of GSTM1 mRNA17381134
D002244CarbonGSTM1 gene SNP affects the susceptibility to Carbon21138591
D002246Carbon DisulfideGSTM1 gene polymorphism affects the metabolism of Carbon Disulfide17333241
D002251Carbon TetrachlorideCarbon Tetrachloride results in increased expression of GSTM1 protein15650968
D002251Carbon Tetrachloride[Carbon Tetrachloride co-treated with Diethylnitrosamine] results in decreased activity of GSTM1 protein12725062
D002251Carbon TetrachlorideCarbon Tetrachloride results in decreased activity of GSTM1 protein polymorphism12611589
D002251Carbon TetrachlorideGSTM1 protein polymorphism affects the susceptibility to Carbon Tetrachloride12611589
D002251Carbon TetrachlorideTea inhibits the reaction [[Carbon Tetrachloride co-treated with Diethylnitrosamine] results in decreased activity of GSTM1 protein]12725062
D002330CarmustineGSTM1 gene affects the susceptibility to Carmustine16087946
D002330CarmustineGSTM1 gene affects the susceptibility to [Carmustine co-treated with Cyclophosphamide co-treated with Cisplatin]16087946
D002330CarmustineGSTM1 protein results in decreased susceptibility to Carmustine20067466
D002509CephaloridineCephaloridine results in increased expression of GSTM1 mRNA18172885|1850078
D002635Chenodeoxycholic AcidChenodeoxycholic Acid binds to and results in decreased activity of GSTM1 protein3954743
D002699ChlorambucilGSTM1 protein results in decreased susceptibility to Chlorambucil15044619|2006746
D020111Chlorodiphenyl (54% Chlorine)Chlorodiphenyl (54% Chlorine) results in increased expression of GSTM1 mRNA18178546
D002737ChloropreneChloroprene results in increased expression of GSTM1 mRNA23125180
D004390Chlorpyrifos[Atrazine co-treated with Chlorpyrifos co-treated with Endosulfan] results in increased expression of GSTM1 mRNA22515965
D004390ChlorpyrifosChlorpyrifos affects the expression of GSTM1 mRNA19440498
D004390ChlorpyrifosChlorpyrifos results in increased expression of GSTM1 mRNA17452286
D019826Cholic AcidCholic Acid binds to and results in decreased activity of GSTM1 protein3954743
C074702chromium hexavalent ionAscorbic Acid inhibits the reaction [chromium hexavalent ion results in decreased expression of GSTM1 mRNA]23470461
C074702chromium hexavalent ionchromium hexavalent ion results in decreased expression of GSTM1 mRNA23470461
C031180chryseneGSTM1 protein affects the metabolism of [chrysene co-treated with Glutathione]9403173
C021977chrysene,2-diol-3,4-epoxide-1"GSTM1 protein results in increased glutathionylation of chrysene,2-diol-3,4-epoxide-1"9308905
C012842Cibacron Blue F 3GACibacron Blue F 3GA inhibits the reaction [GSTM1 protein affects the metabolism of Dinitrochlorobenzene]7733673
C012842Cibacron Blue F 3GACibacron Blue F 3GA results in decreased activity of GSTM1 protein7733673
C012843cinnamic aldehydecinnamic aldehyde results in increased expression of GSTM1 mRNA28219650
C019304ciprofibrateciprofibrate results in decreased expression of GSTM1 mRNA7676460
D002994ClofibrateClofibrate results in decreased expression of GSTM1 mRNA19952500
D002994ClofibrateClofibrate results in increased expression of GSTM1 mRNA22496397
D002994ClofibrateClofibrate results in decreased expression of GSTM1 mRNA11328961
D002994ClofibrateClofibrate results in decreased expression of GSTM1 protein16470657
D002994ClofibrateGSTM1 affects the susceptibility to Clofibrate16800819
D003024ClozapineGSTM1 protein results in decreased activity of Clozapine20849150
D003024ClozapineGSTM1 protein results in increased glutathionylation of Clozapine20849150
D003024ClozapineClozapine results in increased expression of GSTM1 mRNA15860345
D003300Copper[ATP7A gene mutant form results in increased abundance of Copper] which results in increased expression of GSTM1 mRNA15467011
C515714copper (N-2-hydroxyacetophenone)glycinatecopper (N-2-hydroxyacetophenone)glycinate results in decreased expression of GSTM1 protein16289015
C515714copper (N-2-hydroxyacetophenone)glycinate[copper (N-2-hydroxyacetophenone)glycinate results in decreased expression of GSTM1 protein] which results in increased susceptibility to Doxorubicin16289015
D003407CreosoteCreosote results in increased expression of GSTM1 mRNA19389177
C007164cumene hydroperoxideGSTM1 protein affects the metabolism of cumene hydroperoxide10973735
C007164cumene hydroperoxideGSTM1 protein affects the metabolism of cumene hydroperoxide11684093
D003471CuprizoneCuprizone results in increased expression of GSTM1 mRNA26577399
C057862cyanoginosin LRGSTM1 protein results in increased glutathionylation of and affects the susceptibility to cyanoginosin LR21504230
C057862cyanoginosin LRcyanoginosin LR results in decreased expression of GSTM1 mRNA17383702
C057862cyanoginosin LRcyanoginosin LR results in increased expression of GSTM1 mRNA17654400
D003520CyclophosphamideGSTM1 gene affects the susceptibility to [Carmustine co-treated with Cyclophosphamide co-treated with Cisplatin]16087946
D003520Cyclophosphamide[GSTM1 protein co-treated with CYP2C9 protein] results in increased susceptibility to [Busulfan co-treated with Cyclophosphamide]28744217
C093628cyproconazolecyproconazole results in increased expression of GSTM1 mRNA22334560
C093628cyproconazolecyproconazole results in increased expression of GSTM1 mRNA25182419
D003545CysteineCysteine affects the expression of GSTM1 mRNA11040448
D003561CytarabineGSTM1 gene polymorphism affects the susceptibility to Cytarabine15713801
D003630DaunorubicinGSTM1 gene polymorphism affects the susceptibility to Daunorubicin15713801
C010902decabromobiphenyl etherdecabromobiphenyl ether results in increased expression of GSTM1 mRNA19270788
D013759DronabinolDronabinol results in increased expression of GSTM1 mRNA21542829
C479072delta-tocopherol[alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of GSTM1 mRNA]22389237
D003907DexamethasoneGSTM1 protein inhibits the reaction [Dexamethasone results in increased phosphorylation of BCL2L11 protein]20067466
D003907DexamethasoneGSTM1 protein results in decreased susceptibility to Dexamethasone20067466
D003907DexamethasoneDexamethasone results in increased expression of GSTM1 mRNA21041162|2273378
D003907DexamethasoneDexamethasone results in increased expression of GSTM1 mRNA11328961|1394205
D003976DiazinonDiazinon results in increased expression of GSTM1 mRNA17452286
C041517dibenzo(a,l)pyrene"GSTM1 protein affects the metabolism of and results in decreased activity of [dibenzo(a,l)pyrene co-treated with Glutathione]"11849043
C061481dibenzoylmethanedibenzoylmethane results in increased expression of GSTM1 mRNA17942926
C061481dibenzoylmethane[sulforafan co-treated with dibenzoylmethane] results in increased expression of GSTM1 mRNA17942926
D003999Dichloroacetic AcidDichloroacetic Acid results in increased expression of GSTM1 mRNA28962523
D002945CisplatinGSTM1 gene affects the susceptibility to [Carmustine co-treated with Cyclophosphamide co-treated with Cisplatin]16087946
D002945CisplatinGSTM1 gene polymorphism affects the susceptibility to [Paclitaxel co-treated with Cisplatin]12851839
D002945CisplatinGSTM1 protein affects the susceptibility to Cisplatin16217747|2208540
D002945CisplatinCisplatin results in increased expression of GSTM1 mRNA21151649
D004008DiclofenacDiclofenac results in decreased activity of GSTM1 protein27183920
D004008DiclofenacDiclofenac results in decreased expression of GSTM1 mRNA26934552
C121718dicyclanildicyclanil results in increased expression of GSTM1 mRNA15664270
C036042dicyclohexyl phthalatedicyclohexyl phthalate results in increased expression of GSTM1 mRNA26924002
D004041Dietary FatsDietary Fats affects the expression of GSTM1 mRNA19680557
D004041Dietary Fats[Dietary Fats co-treated with Dietary Sucrose] results in decreased expression of GSTM1 mRNA28433925
D004041Dietary Fats[Dietary Fats co-treated with Thioctic Acid] results in increased expression of GSTM1 mRNA18367378
D004041Dietary FatsDietary Fats results in decreased expression of GSTM1 mRNA25016146
D004042Dietary Fats, Unsaturated"[perfluorooctanoic acid co-treated with Dietary Fats, Unsaturated] results in increased expression of GSTM1 mRNA"23626681
D019422Dietary Sucrose[Dietary Fats co-treated with Dietary Sucrose] results in decreased expression of GSTM1 mRNA28433925
D004051Diethylhexyl PhthalateDiethylhexyl Phthalate results in increased expression of GSTM1 mRNA19245819|1985064
D004051Diethylhexyl PhthalatePPARA protein inhibits the reaction [Diethylhexyl Phthalate results in increased expression of GSTM1 mRNA]19850644
D004051Diethylhexyl Phthalate"[Tetrachlorodibenzodioxin co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Diethylhexyl Phthalate co-treated with bisphenol A] results in decreased expression of GSTM1 mRNA"28433925
C014476diethyl maleatediethyl maleate results in decreased expression of GSTM1 protein21161181
D004052Diethylnitrosamine"[2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Diethylnitrosamine] results in increased expression of GSTM1 protein"23457121
D004052Diethylnitrosamine[Carbon Tetrachloride co-treated with Diethylnitrosamine] results in decreased activity of GSTM1 protein12725062
D004052Diethylnitrosamine[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of GSTM1 mRNA18164116|2004503
D004052Diethylnitrosamine[Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of GSTM1 mRNA18544905
D004052Diethylnitrosamine[Diethylnitrosamine co-treated with kojic acid] results in increased expression of GSTM1 mRNA18544905
D004052Diethylnitrosamine[Diethylnitrosamine co-treated with oxfendazole co-treated with isoquercitrin] results in increased expression of GSTM1 mRNA20033131
D004052Diethylnitrosamine[Diethylnitrosamine co-treated with oxfendazole co-treated with Melatonin] results in increased expression of GSTM1 mRNA20033131
D004052Diethylnitrosamine[Diethylnitrosamine co-treated with oxfendazole] results in increased expression of GSTM1 mRNA20033131
D004052Diethylnitrosamine[Diethylnitrosamine co-treated with Thioacetamide co-treated with Thioctic Acid] results in increased expression of GSTM1 mRNA23830814
D004052Diethylnitrosamine[Diethylnitrosamine co-treated with Thioacetamide] results in increased expression of GSTM1 mRNA23830814|2894339
D004052Diethylnitrosamine[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in increased expression of GSTM1 mRNA22129741
D004052Diethylnitrosamine[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of GSTM1 mRNA22129741
D004052Diethylnitrosamineisoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of GSTM1 mRNA]20045035
D004052Diethylnitrosamine[oxfendazole co-treated with Diethylnitrosamine] results in increased expression of GSTM1 mRNA18754104
D004052Diethylnitrosamine[Phenobarbital co-treated with Diethylnitrosamine] results in increased expression of GSTM1 protein20935162
D004052DiethylnitrosamineTea inhibits the reaction [[Carbon Tetrachloride co-treated with Diethylnitrosamine] results in decreased activity of GSTM1 protein]12725062
D004054DiethylstilbestrolDiethylstilbestrol results in increased expression of GSTM1 mRNA21041162
D002117CalcitriolCalcitriol results in increased expression of GSTM1 mRNA21592394
D002117Calcitriol[Testosterone co-treated with Calcitriol] results in increased expression of GSTM1 mRNA21592394
C015835dimethyl-4-toluidinedimethyl-4-toluidine results in increased expression of GSTM1 mRNA27638505
C024629dimethyl phthalatedimethyl phthalate results in increased expression of GSTM1 mRNA26924002
D004121Dimethyl SulfoxideDimethyl Sulfoxide inhibits the reaction [Thioacetamide results in decreased expression of GSTM1 protein]12370186
D004137DinitrochlorobenzeneGSTM1 protein affects the metabolism of Dinitrochlorobenzene14508638
D004137DinitrochlorobenzeneGSTM1 protein affects the metabolism of Dinitrochlorobenzene9571047
D004137DinitrochlorobenzeneDinitrochlorobenzene binds to GSTM1 protein22085405
D004137DinitrochlorobenzeneGSTM1 protein affects the metabolism of Dinitrochlorobenzene3570286|9545290
D004137DinitrochlorobenzeneGSTM1 protein results in increased glutathionylation of Dinitrochlorobenzene28762043
D004137DinitrochlorobenzeneDinitrochlorobenzene affects the expression of GSTM1 mRNA28219650
D004137DinitrochlorobenzeneGSTM1 protein affects the metabolism of Dinitrochlorobenzene12069689
D004137Dinitrochlorobenzenebromotriethylstannane inhibits the reaction [GSTM1 protein affects the metabolism of Dinitrochlorobenzene]7733673
D004137DinitrochlorobenzeneCibacron Blue F 3GA inhibits the reaction [GSTM1 protein affects the metabolism of Dinitrochlorobenzene]7733673
D004137DinitrochlorobenzeneHemin inhibits the reaction [GSTM1 protein affects the metabolism of Dinitrochlorobenzene]7733673
D004137DinitrochlorobenzeneSulfobromophthalein inhibits the reaction [GSTM1 protein affects the metabolism of Dinitrochlorobenzene]7733673
D004137Dinitrochlorobenzenetriphenyltin chloride inhibits the reaction [GSTM1 protein affects the metabolism of Dinitrochlorobenzene]7733673
D004137DinitrochlorobenzeneGSTM1 protein affects the metabolism of Dinitrochlorobenzene11368767
D004137DinitrochlorobenzeneGSTM1 protein affects the metabolism of [Dinitrochlorobenzene analog co-treated with Glutathione]8867999
D004137DinitrochlorobenzeneGSTM1 protein affects the metabolism of [Dinitrochlorobenzene co-treated with Glutathione]2375757
D004137DinitrochlorobenzeneGSTM1 protein affects the metabolism of [Dinitrochlorobenzene co-treated with Glutathione analog]2375757
D004137DinitrochlorobenzeneGSTM1 protein affects the metabolism of [Dinitrochlorobenzene co-treated with Glutathione analog]2904809
C051904dinophysistoxin 1dinophysistoxin 1 results in increased expression of GSTM1 mRNA28939011
D004147DioxinsGSTM1 gene mutant form results in increased susceptibility to Dioxins27939992
D004178DiquatDiquat results in decreased expression of GSTM1 mRNA7676460
D004050DitiocarbDitiocarb binds to and results in decreased activity of GSTM1 protein6095330
D004237DiuronDiuron results in increased expression of GSTM1 mRNA21551480
D004281Docosahexaenoic Acids[Docosahexaenoic Acids co-treated with Benzo(a)pyrene] results in decreased expression of GSTM1 protein25956473
D004281Docosahexaenoic Acids[Docosahexaenoic Acids co-treated with benzo(b)fluoranthene] results in decreased expression of GSTM1 protein25956473
D004281Docosahexaenoic Acids[Docosahexaenoic Acids co-treated with benzo(k)fluoranthene] results in decreased expression of GSTM1 protein25956473
D004281Docosahexaenoic Acids[Docosahexaenoic Acids co-treated with pyrene] results in decreased expression of GSTM1 protein25956473
D004298DopamineDopamine analog results in decreased activity of GSTM1 protein8131222
D004317Doxorubicin[copper (N-2-hydroxyacetophenone)glycinate results in decreased expression of GSTM1 protein] which results in increased susceptibility to Doxorubicin16289015
D004317DoxorubicinDoxorubicin results in increased expression of GSTM1 mRNA16243910
D004317DoxorubicinGSTM1 protein results in decreased susceptibility to Doxorubicin16289015
D004317DoxorubicinDoxorubicin results in increased oxidation of GSTM1 protein28818578
C509867E804 bisindoleE804 bisindole results in decreased expression of GSTM1 mRNA23107598
C509867E804 bisindoleLipopolysaccharides inhibits the reaction [E804 bisindole results in decreased expression of GSTM1 mRNA]23107598
C042986ebselenebselen binds to and results in decreased activity of [GSTM1 protein binds to GSTM2 protein]8147899
D004726Endosulfan[Atrazine co-treated with Chlorpyrifos co-treated with Endosulfan] results in increased expression of GSTM1 mRNA22515965
D004785Environmental PollutantsEnvironmental Pollutants results in increased expression of GSTM1 mRNA12655031
D004785Environmental PollutantsGSTM1 gene polymorphism affects the susceptibility to Environmental Pollutants24036326
D004811EpichlorohydrinGSTM1 gene polymorphism affects the susceptibility to Epichlorohydrin15091291
C045651epigallocatechin gallateepigallocatechin gallate results in increased expression of GSTM1 mRNA25585349
C109476epoxiconazoleepoxiconazole results in increased expression of GSTM1 mRNA22334560
C109476epoxiconazoleepoxiconazole results in increased expression of GSTM1 mRNA25182419
C073539erucinerucin results in increased expression of GSTM1 protein18823965
D002393Estrogens, Catechol"GSTM1 protein affects the metabolism of Estrogens, Catechol metabolite"15455371
D004976Ethacrynic AcidGSTM1 protein affects the metabolism of Ethacrynic Acid12069689
D000431EthanolGSTM1 gene mutant form affects the susceptibility to Ethanol20171022
D000431EthanolGSTM1 gene polymorphism affects the susceptibility to Ethanol15932176
D000431EthanolEthanol results in increased expression of GSTM1 mRNA23273579
D004997Ethinyl EstradiolEthinyl Estradiol affects the expression of GSTM1 mRNA17351261
D004997Ethinyl EstradiolEthinyl Estradiol results in decreased expression of GSTM1 mRNA15834898
D005015EthoxyquinEthoxyquin results in increased expression of GSTM1 mRNA18723825
D005015EthoxyquinEthoxyquin results in increased expression of GSTM1 protein11309284
D005015EthoxyquinEthoxyquin results in increased expression of GSTM1 mRNA19695238
D005015EthoxyquinEthoxyquin results in increased expression of GSTM1 protein8198522
D005034Ethylmercuric ChlorideEthylmercuric Chloride results in decreased activity of GSTM1 protein1793546
D005047EtoposideGSTM1 gene polymorphism affects the susceptibility to Etoposide15713801
D005054EugenolEugenol analog results in decreased activity of GSTM1 protein8620581
D005054EugenolEugenol analog results in decreased activity of GSTM1 protein8620581
C436526EUK-189EUK-189 inhibits the reaction [SOD2 gene mutant form results in increased expression of GSTM1 mRNA]15964507
D005227Fatty AcidsFatty Acids binds to and results in increased activity of GSTM1 protein2277038
C047360felbamatefelbamate results in increased expression of GSTM1 mRNA17381134
C540355fenamidonefenamidone results in increased expression of GSTM1 mRNA27029645
C540355fenamidonesulforafan inhibits the reaction [fenamidone results in increased expression of GSTM1 mRNA]27029645
D018120FinasterideFinasteride results in increased expression of GSTM1 mRNA24136188
C082360fipronilfipronil results in increased expression of GSTM1 mRNA23962444
D015725FluconazoleFluconazole results in increased expression of GSTM1 mRNA16730040
D0150732-Acetylaminofluorene2-Acetylaminofluorene results in increased expression of GSTM1 mRNA17070881
D005485FlutamideFlutamide results in increased expression of GSTM1 mRNA24136188
C056933fumonisin B1fumonisin B1 results in increased expression of GSTM1 mRNA16221962
C039281furanfuran results in increased expression of GSTM1 mRNA20194422|2418370
C039281furanfuran results in increased expression of GSTM1 mRNA25539665|2619464
C040029gabapentingabapentin results in increased expression of GSTM1 mRNA17381134
D024504gamma-Tocopherolgamma-Tocopherol results in increased expression of GSTM1 mRNA19115203
D024504gamma-Tocopherolgamma-Tocopherol results in increased expression of GSTM1 protein19115203
D024504gamma-Tocopherol[alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of GSTM1 mRNA]22389237
C007835geniposidegeniposide results in increased expression of GSTM1 mRNA14646352
C007835geniposidegeniposide results in increased expression of GSTM1 protein14646352
D005839GentamicinsGentamicins results in increased expression of GSTM1 mRNA22061828
D005961GlucosinolatesGlucosinolates results in increased expression of GSTM1 protein15570060
D005978GlutathioneGSTM1 protein affects the metabolism of Glutathione10973735
D005978Glutathione4-O-decyl-gabosine D inhibits the reaction [Glutathione binds to GSTM1 protein]22085405
D005978GlutathioneGlutathione binds to GSTM1 protein22085405
D005978GlutathioneGSTM1 gene mutant form results in decreased abundance of Glutathione25420021
D005978Glutathione"GSTM1 protein affects the metabolism of [1,2,5,6-dibenzanthracene co-treated with Glutathione]"9403173
D005978Glutathione"GSTM1 protein affects the metabolism of [15-deoxy-delta(12,14)-prostaglandin J2 co-treated with Glutathione]"14979731
D005978Glutathione"GSTM1 protein affects the metabolism of [7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide co-treated with Glutathione]"9403173
D005978Glutathione"GSTM1 protein affects the metabolism of and results in decreased activity of [7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide co-treated with Glutathione]"11849043
D005978Glutathione"GSTM1 protein affects the metabolism of and results in decreased activity of [dibenzo(a,l)pyrene co-treated with Glutathione]"11849043
D005978GlutathioneGSTM1 protein affects the metabolism of [Benzo(a)pyrene co-treated with Glutathione]9403173
D005978GlutathioneGSTM1 protein affects the metabolism of [chrysene co-treated with Glutathione]9403173
D005978GlutathioneGSTM1 protein affects the metabolism of Glutathione7826396|8886613|
D005978GlutathioneGSTM1 protein affects the metabolism of [hydratropic aldehyde co-treated with Glutathione]11368548
D005978Glutathione[GSTM1 protein co-treated with 4-hydroxy-2-nonenal] results in decreased abundance of Glutathione21925487
D005978GlutathioneGSTM1 protein affects the metabolism of [4-chloronitrobenzene analog co-treated with Glutathione]8867999
D005978GlutathioneGSTM1 protein affects the metabolism of [Dinitrochlorobenzene analog co-treated with Glutathione]8867999
D005978GlutathioneGSTM1 protein affects the metabolism of [Dinitrochlorobenzene co-treated with Glutathione]2375757
D005978GlutathioneGSTM1 protein affects the metabolism of [Dinitrochlorobenzene co-treated with Glutathione analog]2375757
D005978GlutathioneGlutathione analog binds to and results in decreased activity of GSTM1 protein1883342
D005978GlutathioneGlutathione deficiency results in increased expression of GSTM1 mRNA15345336
D005978GlutathioneGSTM1 protein affects the metabolism of [4-chloronitrobenzene analog co-treated with Glutathione]8973562
D005978GlutathioneGSTM1 protein affects the metabolism of [Dinitrochlorobenzene co-treated with Glutathione analog]2904809
D005978GlutathioneGSTM1 protein affects the metabolism of Glutathione6095330
D005978GlutathioneGSTM1 protein affects the metabolism of [styrene oxide co-treated with Glutathione]2604743
C071834glycidamide[CYP2E1 gene polymorphism co-treated with GSTM1 gene polymorphism] affects the abundance of glycidamide19131562
C071834glycidamide[CYP2E1 gene polymorphism co-treated with GSTM1 gene polymorphism co-treated with GSTT1 gene polymorphism] affects the abundance of glycidamide19131562
C071834glycidamideGSTM1 gene polymorphism affects the abundance of glycidamide19131562
D006016GlycolatesGlycolates analog binds to and results in decreased activity of GSTM1 protein6686184
C412815GW 4064GW 4064 results in increased expression of GSTM1 mRNA26655953
D006220HaloperidolHaloperidol results in increased expression of GSTM1 mRNA15860345
D006427HeminHemin inhibits the reaction [GSTM1 protein affects the metabolism of Dinitrochlorobenzene]7733673
D006427HeminHemin results in decreased activity of GSTM1 protein7733673
D006540HerbicidesHerbicides binds to and results in decreased activity of GSTM1 protein6686184
D006581HexachlorobenzeneHexachlorobenzene results in decreased expression of GSTM1 mRNA15159207
C001335hexachlorobutadienehexachlorobutadiene results in increased expression of GSTM1 protein21259293|2190505
C033550hexylglutathionehexylglutathione binds to and results in decreased activity of GSTM1 protein9571047
D017313FenretinideFenretinide results in increased expression of GSTM1 mRNA28973697
C013026hydratropic aldehydeGSTM1 protein affects the metabolism of [hydratropic aldehyde co-treated with Glutathione]11368548
C013026hydratropic aldehydeGSTM1 protein results in decreased activity of hydratropic aldehyde11368548
C013026hydratropic aldehydehydratropic aldehyde results in decreased activity of GSTM1 protein11368548
C029424hydrazineGSTM1 gene mutant form results in increased abundance of hydrazine18544910
D006843Hydrocarbons, Chlorinated"GSTM1 gene polymorphism affects the susceptibility to Hydrocarbons, Chlorinated"26479327
D006861Hydrogen PeroxideGSTM1 protein results in decreased susceptibility to Hydrogen Peroxide10661898
D006861Hydrogen Peroxide[HP gene polymorphism co-treated with GSTM1 gene polymorphism] affects the susceptibility to Hydrogen Peroxide20444272
C031927hydroquinoneGSTM1 gene polymorphism affects the susceptibility to hydroquinone15141365
C029899imidazoleimidazole results in increased expression of GSTM1 mRNA8951341
C016517indole-3-carbinolindole-3-carbinol results in increased expression of GSTM1 protein11309284
C016517indole-3-carbinol[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in increased expression of GSTM1 mRNA22129741
C016517indole-3-carbinol[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of GSTM1 mRNA22129741
D007213IndomethacinIndomethacin results in increased expression of GSTM1 mRNA18299717
D007306InsecticidesGSTM1 gene polymorphism affects the susceptibility to Insecticides12930676
D007460IodoacetamideIodoacetamide results in decreased activity of GSTM1 protein1520269
D007501IronIron results in decreased expression of GSTM1 protein11755321
D007501IronIron results in increased expression of GSTM1 mRNA11755321
D007501IronIron results in increased expression of GSTM1 protein11755321
D007505Iron-Dextran Complex[Iron-Dextran Complex co-treated with Tetrachlorodibenzodioxin] results in increased expression of GSTM1 protein9443932
D007505Iron-Dextran ComplexIron-Dextran Complex results in increased expression of GSTM1 protein9443932
C031050isomethyleugenolisomethyleugenol results in decreased activity of GSTM1 protein8620581
C031050isomethyleugenolisomethyleugenol results in decreased activity of GSTM1 protein8620581
D007538IsoniazidGSTM1 protein inhibits the reaction [CYP2E1 protein results in increased susceptibility to Isoniazid]28762043
D007538IsoniazidGSTM1 protein results in decreased susceptibility to Isoniazid28762043
C016527isoquercitrin[Diethylnitrosamine co-treated with oxfendazole co-treated with isoquercitrin] results in increased expression of GSTM1 mRNA20033131
C016527isoquercitrinisoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of GSTM1 mRNA]20045035
C098607JP8 aviation fuelJP8 aviation fuel results in increased expression of GSTM1 protein10959803
C053401kahweol[cafestol co-treated with kahweol] results in increased expression of GSTM1 protein11346484
C033997kahweol palmitate[cafestol co-treated with kahweol palmitate] results in increased expression of GSTM1 protein11309284
D007654KetoconazoleKetoconazole results in increased expression of GSTM1 protein17966066
C011890kojic acid[Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of GSTM1 mRNA18544905
C011890kojic acid[Diethylnitrosamine co-treated with kojic acid] results in increased expression of GSTM1 mRNA18544905
D007854Lead[GSTM1 gene mutant form co-treated with GSTT1 gene mutant form] promotes the reaction [Lead results in increased expression of CRP protein]23484121
D007854Lead[GSTM1 gene mutant form co-treated with GSTT1 gene mutant form] results in increased susceptibility to Lead23484121
D007854LeadGSTM1 gene mutant form promotes the reaction [Lead results in increased expression of CRP protein]23484121
D007854LeadGSTM1 gene mutant form results in increased susceptibility to Lead23484121
C008261lead acetatelead acetate affects the localization of GSTM1 protein9750042
C008261lead acetatelead acetate results in increased expression of GSTM1 mRNA9750042
C008261lead acetatelead acetate results in increased expression of GSTM1 protein7878682|9750042
D017705LignansLignans results in increased expression of GSTM1 mRNA26678224
C008281limonenelimonene results in increased expression of GSTM1 protein23159986
D008054Lipid PeroxidesGSTM1 protein affects the metabolism of and results in decreased susceptibility to Lipid Peroxides9576856
C482199lipopolysaccharide, E coli O55-B5"[lipopolysaccharide, E coli O55-B5 co-treated with Benzo(a)pyrene] affects the expression of GSTM1 mRNA"28987381
D008070LipopolysaccharidesLipopolysaccharides results in increased expression of GSTM1 mRNA24001438
D008070LipopolysaccharidesPlant Extracts inhibits the reaction [Lipopolysaccharides results in increased expression of GSTM1 mRNA]24001438
D008070LipopolysaccharidesLipopolysaccharides inhibits the reaction [E804 bisindole results in decreased expression of GSTM1 mRNA]23107598
D008070LipopolysaccharidesLipopolysaccharides results in decreased expression of GSTM1 mRNA27339419
D008094LithiumLithium results in increased expression of GSTM1 mRNA18082333
D008094LithiumLithium results in increased expression of GSTM1 protein18296634
D008095Lithocholic AcidLithocholic Acid results in increased expression of GSTM1 mRNA20977460
D008095Lithocholic AcidNFE2L2 protein promotes the reaction [Lithocholic Acid results in increased expression of GSTM1 mRNA]20977460
D008095Lithocholic AcidLithocholic Acid binds to and results in decreased activity of GSTM1 protein3954743
D008528Mefenamic AcidGSTM1 protein results in increased glutathionylation of Mefenamic Acid analog25372302
D008550Melatonin[Diethylnitrosamine co-treated with oxfendazole co-treated with Melatonin] results in increased expression of GSTM1 mRNA20033131
D008558MelphalanGSTM1 protein results in decreased susceptibility to Melphalan20067466
D015122MercaptopurineGSTM1 gene polymorphism affects the susceptibility to Mercaptopurine15713801
D008627Mercuric ChlorideMercuric Chloride results in increased expression of GSTM1 protein9434069
D008628MercuryGSTM1 gene polymorphism affects the abundance of Mercury25728017
D008628MercuryGSTM1 gene polymorphism affects the susceptibility to Mercury20194072
D008628Mercury[GSTM1 gene polymorphism co-treated with GSTT1 gene polymorphism] affects the susceptibility to Mercury24319713
D008628MercuryGSTM1 polymorphism affects the susceptibility to Mercury17716707
D008628Mercury[GSTP1 gene polymorphism co-treated with GSTM1 gene polymorphism] affects the abundance of Mercury19515364
D058955MetalloidsGSTM1 gene polymorphism affects the susceptibility to Metalloids24036326
D008670MetalsGSTM1 gene polymorphism affects the susceptibility to Metals14504370|2403632
D008694MethamphetamineGSTM1 gene polymorphism affects the susceptibility to Methamphetamine15048646
D008694MethamphetamineGSTM1 protein results in decreased susceptibility to Methamphetamine19254865
D008715MethionineMethionine affects the expression of GSTM1 mRNA11040448
D008727MethotrexateGSTM1 gene polymorphism affects the susceptibility to Methotrexate15713801
D008727MethotrexateGSTM1 mRNA results in decreased susceptibility to Methotrexate23675469
D008727MethotrexateMethotrexate affects the expression of GSTM1 mRNA18502557
D008748MethylcholanthreneMethylcholanthrene results in increased expression of GSTM1 mRNA11328961|2327357
D008750MethyldopaMethyldopa analog results in decreased activity of GSTM1 protein8131222
C005223methyleugenolmethyleugenol results in decreased activity of GSTM1 protein8620581
C005223methyleugenolmethyleugenol results in decreased activity of GSTM1 protein8620581
C004925methylmercuric chloridemethylmercuric chloride results in decreased expression of GSTM1 mRNA12215206
C004925methylmercuric chloridemethylmercuric chloride results in decreased activity of GSTM1 protein1793546
D008767Methylmercury CompoundsGSTM1 gene polymorphism affects the metabolism of Methylmercury Compounds24696865
D0156551-Methyl-4-phenylpyridiniumU 0126 affects the reaction [1-Methyl-4-phenylpyridinium affects the expression of GSTM1 mRNA]12710931
D0156551-Methyl-4-phenylpyridinium1-Methyl-4-phenylpyridinium results in decreased expression of GSTM1 mRNA16026605
C063855microcystin RRGSTM1 protein results in increased glutathionylation of microcystin RR23538035
D052998MicrocystinsMicrocystins affects the expression of GSTM1 mRNA19790251
C016599mono-(2-ethylhexyl)phthalatemono-(2-ethylhexyl)phthalate results in increased expression of GSTM1 protein27384973
D016686Monocrotaline[Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of GSTM1 protein21224054
C020300monomethylarsonic acidmonomethylarsonic acid results in increased expression of GSTM1 mRNA16436460
C020300monomethylarsonic acidmonomethylarsonic acid results in increased expression of GSTM1 protein16436460
C517284monomethyl phthalatemonomethyl phthalate results in increased expression of GSTM1 mRNA26924002
C005939muconic acid[GSTM1 protein affects the metabolism of Benzene] which affects the abundance of muconic acid10511268
D009151Mustard GasMustard Gas results in decreased expression of GSTM1 mRNA18955075
C583365N-(2-(1,1'-bicyclopropyl)-2-ylphenyl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide"N-(2-(1,1'-bicyclopropyl)-2-ylphenyl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide results in increased expression of GSTM1 mRNA"29244179
C569465N-acetyl-S-(2-carbamoylethyl)cysteine[GSTM1 gene polymorphism affects the metabolism of Acrylamide] which affects the chemical synthesis of N-acetyl-S-(2-carbamoylethyl)cysteine21402133
D037742Nanotubes, Carbon"Nanotubes, Carbon analog results in decreased expression of GSTM1 mRNA"25554681|2562005
D037742Nanotubes, Carbon"Nanotubes, Carbon results in decreased expression of GSTM1 mRNA"25554681|2562005
C031721naphthalenenaphthalene results in increased expression of GSTM1 mRNA20500019
C031721naphthalenenaphthalene affects the expression of GSTM1 protein10959795
C031721naphthalenenaphthalene results in decreased expression of GSTM1 protein19438287
C051752nefazodonenefazodone results in increased expression of GSTM1 mRNA24136188
D019829NevirapineGSTM1 protein results in increased glutathionylation of Nevirapine metabolite27989146
D009532NickelNickel results in decreased expression of GSTM1 mRNA24768652|2558310
C012655nimesulidenimesulide results in increased expression of GSTM1 mRNA24136188
D009569Nitric OxideNitric Oxide deficiency results in increased expression of GSTM1 mRNA15878706
D009585Nitrogen DioxideGSTM1 gene polymorphism affects the susceptibility to Nitrogen Dioxide22732554
C025589ochratoxin Aochratoxin A results in decreased expression of GSTM1 mRNA23358140
C025589ochratoxin Aochratoxin A results in decreased expression of GSTM1 protein17110534
C014138octachlorostyreneoctachlorostyrene results in increased expression of GSTM1 mRNA18036774
D019319Okadaic AcidOkadaic Acid results in increased expression of GSTM1 mRNA28939011
C026209oltiprazNFE2L2 protein affects the reaction [oltipraz results in increased expression of GSTM1 mRNA]22496397
C026209oltipraz[oltipraz results in increased activity of NFE2L2 protein] which results in increased expression of GSTM1 mRNA22496397
C026209oltiprazoltipraz results in increased expression of GSTM1 mRNA18723825|2249639
C026209oltiprazoltipraz results in increased expression of GSTM1 mRNA9203627
D015525Fatty Acids, Omega-3"GSTM1 gene polymorphism affects the susceptibility to Fatty Acids, Omega-3"15256483
D010755OrganophosphatesGSTM1 gene polymorphism affects the susceptibility to Organophosphates26318115
C011030oxfendazole[Diethylnitrosamine co-treated with oxfendazole co-treated with isoquercitrin] results in increased expression of GSTM1 mRNA20033131
C011030oxfendazole[Diethylnitrosamine co-treated with oxfendazole co-treated with Melatonin] results in increased expression of GSTM1 mRNA20033131
C011030oxfendazole[Diethylnitrosamine co-treated with oxfendazole] results in increased expression of GSTM1 mRNA20033131
C011030oxfendazole[oxfendazole co-treated with Diethylnitrosamine] results in increased expression of GSTM1 mRNA18754104
D010100OxygenOxygen deficiency results in decreased expression of GSTM1 mRNA19695866
D010126OzoneGSTM1 gene polymorphism affects the susceptibility to Ozone22732554
D010126OzoneGSTM1 gene polymorphism promotes the reaction [NQO1 gene SNP results in increased susceptibility to Ozone]17652311
D010126OzoneGSTM1 gene SNP affects the reaction [MS4A2 gene SNP affects the susceptibility to Ozone]18269668
D010126OzoneGSTM1 gene SNP affects the reaction [TNF gene SNP affects the susceptibility to Ozone]16456144
D010126OzoneGSTM1 gene SNP results in increased susceptibility to Ozone16870661
D010126OzoneGSTM1 protein affects the susceptibility to Ozone11371413
D010126OzoneOzone results in decreased expression of GSTM1 mRNA12763052
D017239PaclitaxelGSTM1 gene polymorphism affects the susceptibility to [Paclitaxel co-treated with Cisplatin]12851839
D000073878Palm OilPalm Oil affects the expression of GSTM1 mRNA19680557
D010269ParaquatParaquat results in increased expression of GSTM1 mRNA16128001
D052638Particulate MatterGSTM1 gene polymorphism affects the susceptibility to Particulate Matter22732554
D052638Particulate MatterGSTM1 mutant form promotes the reaction [Particulate Matter results in increased expression of CD40]21169129
D052638Particulate MatterGSTM1 mutant form promotes the reaction [Particulate Matter results in increased expression of CD80]21169129
D052638Particulate MatterGSTM1 mutant form promotes the reaction [Particulate Matter results in increased expression of CD86]21169129
D052638Particulate MatterGSTM1 mutant form promotes the reaction [Particulate Matter results in increased expression of CXCL8 protein]22867088
D052638Particulate MatterGSTM1 mutant form promotes the reaction [Particulate Matter results in increased expression of FCER2]21169129
D052638Particulate MatterGSTM1 mutant form promotes the reaction [Particulate Matter results in increased expression of IL1B protein]22867088
D052638Particulate MatterGSTM1 mutant form promotes the reaction [Particulate Matter results in increased phosphorylation of AKT1 protein]22867088
D052638Particulate MatterGSTM1 mutant form promotes the reaction [Particulate Matter results in increased phosphorylation of MAPK1 protein]22867088
D052638Particulate MatterGSTM1 mutant form promotes the reaction [Particulate Matter results in increased phosphorylation of MAPK3 protein]22867088
D052638Particulate MatterGSTM1 results in decreased susceptibility to Particulate Matter21169129
D052638Particulate MatterNFE2L2 gene mutant form inhibits the reaction [Particulate Matter results in increased expression of GSTM1 mRNA]18614404
D052638Particulate MatterParticulate Matter results in decreased expression of GSTM1 mRNA18307122
D052638Particulate MatterParticulate Matter results in decreased expression of GSTM1 protein18307122
D052638Particulate MatterParticulate Matter results in increased expression of GSTM1 mRNA18614404
D052638Particulate MatterParticulate Matter results in increased expression of GSTM1 mRNA22352393
C086401pentabromodiphenyl etherpentabromodiphenyl ether results in increased expression of GSTM1 mRNA19270788
D010416PentachlorophenolPentachlorophenol results in increased expression of GSTM1 mRNA23892564
C076994perfluorooctane sulfonic acidperfluorooctane sulfonic acid affects the expression of GSTM1 mRNA19429403
C023036perfluorooctanoic acidperfluorooctanoic acid affects the expression of GSTM1 mRNA18281256|1942940
C023036perfluorooctanoic acid"[perfluorooctanoic acid co-treated with Dietary Fats, Unsaturated] results in increased expression of GSTM1 mRNA"23626681
C023036perfluorooctanoic acidperfluorooctanoic acid results in decreased expression of GSTM1 mRNA18467677
C023036perfluorooctanoic acidPPARA protein promotes the reaction [perfluorooctanoic acid results in decreased expression of GSTM1 mRNA]18467677
D010575PesticidesGSTM1 gene polymorphism affects the susceptibility to Pesticides14504370|1592252
D010575PesticidesGSTM1 protein results in increased susceptibility to Pesticides18550589
C031181phenanthreneGSTM1 gene polymorphism promotes the reaction [CYP1A1 gene polymorphism results in increased metabolism of phenanthrene]17035385
C031181phenanthreneGSTM1 protein affects the metabolism of phenanthrene22674470
C058305phenethyl isothiocyanateGSTM1 protein affects the metabolism of phenethyl isothiocyanate7826396
D010634PhenobarbitalPhenobarbital results in decreased expression of GSTM1 mRNA19952500
D010634PhenobarbitalPhenobarbital results in decreased expression of GSTM1 protein7986210
D010634PhenobarbitalPhenobarbital results in increased expression of GSTM1 mRNA18723825|2040396
D010634Phenobarbital[Phenobarbital co-treated with Diethylnitrosamine] results in increased expression of GSTM1 protein20935162
D010634PhenobarbitalPhenobarbital results in increased expression of GSTM1 mRNA11328961|1738113
D010634PhenobarbitalPhenobarbital results in increased expression of GSTM1 protein8242872
C509597phenylpropylene oxideGSTM1 protein affects the metabolism of phenylpropylene oxide17689871
D010672Phenytoin[Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of GSTM1 protein21224054
D010672PhenytoinPhenytoin results in increased expression of GSTM1 mRNA17381134
D010695PhlorhizinPhlorhizin results in decreased expression of GSTM1 mRNA22538082
D010847PicolinesPicolines results in decreased expression of GSTM1 protein7986210
C004479pimagedinepimagedine inhibits the reaction [Spermidine results in increased expression of GSTM1 mRNA]12763045
D010882Piperonyl ButoxidePiperonyl Butoxide results in increased expression of GSTM1 mRNA18544911
D010882Piperonyl ButoxideTriterpenes promotes the reaction [Piperonyl Butoxide results in increased expression of GSTM1 mRNA]18544911
C006253pirinixic acidpirinixic acid results in decreased expression of GSTM1 mRNA18467677|2081375
C006253pirinixic acidPPARA protein promotes the reaction [pirinixic acid results in decreased expression of GSTM1 mRNA]18467677
D010936Plant ExtractsPlant Extracts inhibits the reaction [Lipopolysaccharides results in increased expression of GSTM1 mRNA]24001438
D010936Plant ExtractsPlant Extracts results in increased expression of GSTM1 protein15570060
D017671Platinum CompoundsGSTM1 affects the susceptibility to Platinum Compounds21844884
D011084Polycyclic Aromatic HydrocarbonsGSTM1 gene polymorphism affects the secretion of Polycyclic Aromatic Hydrocarbons21359562
D011084Polycyclic Aromatic HydrocarbonsGSTM1 gene polymorphism affects the susceptibility to Polycyclic Aromatic Hydrocarbons15036119|1506191
D011084Polycyclic Aromatic HydrocarbonsGSTM1 protein affects the metabolism of and results in decreased activity of Polycyclic Aromatic Hydrocarbons15122594
D011084Polycyclic Aromatic HydrocarbonsGSTM1 protein polymorphism results in increased susceptibility to Polycyclic Aromatic Hydrocarbons11740339
D011084Polycyclic Aromatic HydrocarbonsGSTM1 protein results in decreased activity of Polycyclic Aromatic Hydrocarbons15122594
C095911polycyclic aromatic hydrocarbons-DNA adductGSTM1 protein polymorphism results in increased abundance of polycyclic aromatic hydrocarbons-DNA adduct11967624
D011192Potassium DichromateAscorbic Acid inhibits the reaction [Potassium Dichromate results in decreased expression of GSTM1 mRNA]23470461
D011192Potassium DichromatePotassium Dichromate results in decreased expression of GSTM1 mRNA23470461
D011241PrednisoneGSTM1 gene polymorphism affects the susceptibility to Prednisone15713801
D011285Pregnenolone CarbonitrileNR1I2 protein affects the reaction [Pregnenolone Carbonitrile results in increased expression of GSTM1 mRNA]22496397
D011285Pregnenolone CarbonitrilePregnenolone Carbonitrile promotes the reaction [NR1I2 protein binds to GSTM1 5' UTR]20693526
D011285Pregnenolone Carbonitrile[Pregnenolone Carbonitrile results in increased activity of NR1I2 protein] which results in increased expression of GSTM1 mRNA22496397
D011285Pregnenolone CarbonitrilePregnenolone Carbonitrile results in increased expression of GSTM1 mRNA18723825|2249639
D011285Pregnenolone CarbonitrilePregnenolone Carbonitrile results in increased expression of GSTM1 mRNA19162173
C045950propiconazolepropiconazole results in increased expression of GSTM1 mRNA21278054|2233456
C045950propiconazolepropiconazole affects the expression of GSTM1 mRNA17383973
C100008prostaglandin A2GSTM1 protein affects the metabolism of prostaglandin A29084911
D054328Proton Pump InhibitorsProton Pump Inhibitors results in increased expression of GSTM1 mRNA25626140
C513428pyrachlostrobinpyrachlostrobin results in increased expression of GSTM1 mRNA27029645
D011719PyrazinesPyrazines results in decreased expression of GSTM1 protein7986210
C031280pyrazolepyrazole results in increased expression of GSTM1 mRNA17945193
C031280pyrazolepyrazole results in increased expression of GSTM1 protein14610226
C030984pyrene[Docosahexaenoic Acids co-treated with pyrene] results in decreased expression of GSTM1 protein25956473
C030984pyrenepyrene results in increased expression of GSTM1 mRNA26160115
D011802QuinidineQuinidine results in decreased activity of GSTM1 protein11807801
D011803QuinineQuinine results in decreased activity of GSTM1 protein11807801
C502234r-1,t-2,3,c-4-tetrahydroxy-1,2,3,4-tetrahydrophenanthrene"GSTM1 protein affects the chemical synthesis of r-1,t-2,3,c-4-tetrahydroxy-1,2,3,4-tetrahydrophenanthrene"22674470
C059514resveratrolresveratrol results in increased expression of GSTM1 mRNA19228061
D015474IsotretinoinIsotretinoin results in decreased expression of GSTM1 mRNA15982314
C013672riddelliineriddelliine results in decreased expression of GSTM1 mRNA18047727
D012293Rifampin[Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of GSTM1 protein21224054
D012294RifamycinsRifamycins results in decreased expression of GSTM1 protein7986210
C089730rosiglitazonerosiglitazone affects the expression of GSTM1 mRNA17245590
D012402RotenoneRotenone affects the expression of GSTM1 mRNA23186747
D012822Silicon DioxideSilicon Dioxide analog results in decreased expression of GSTM1 mRNA25895662
D012834SilverSilver results in increased expression of GSTM1 mRNA27131904
D012906SmokeGSTM1 affects the susceptibility to Smoke19464563
D012906Smoke[GSTM1 polymorphism co-treated with Smoke] affects the abundance of S-phenyl-N-acetylcysteine21300142
C017947sodium arseniteGSTM1 gene polymorphism affects the susceptibility to sodium arsenite25395496
C017947sodium arseniteNFE2L1 protein alternative form inhibits the reaction [sodium arsenite results in increased expression of GSTM1 mRNA]28549828
C017947sodium arsenitesodium arsenite results in increased expression of GSTM1 mRNA28549828
D012982Sodium, Dietary"GSTM1 gene polymorphism affects the susceptibility to Sodium, Dietary"14696128
D012969Sodium FluorideSodium Fluoride results in decreased expression of GSTM1 mRNA28089781
D012997SolventsGSTM1 gene polymorphism affects the susceptibility to Solvents17449559
D012997SolventsGSTM1 polymorphism affects the susceptibility to Solvents24914957
D012999SomanSoman results in decreased expression of GSTM1 mRNA19281266
D053260SootGSTM1 affects the susceptibility to Soot21385671
D053260SootGSTM1 gene SNP affects the susceptibility to Soot19884647
D053260SootSoot results in decreased expression of GSTM1 mRNA22461453
D053260SootSoot affects the expression of GSTM1 mRNA23065132
D053260SootSoot results in decreased expression of GSTM1 mRNA21914721
D013095Spermidinepimagedine inhibits the reaction [Spermidine results in increased expression of GSTM1 mRNA]12763045
D013095SpermidineSpermidine results in increased expression of GSTM1 mRNA12763045
C053003S-phenyl-N-acetylcysteineGSTA1 gene polymorphism affects the reaction [GSTM1 gene polymorphism affects the abundance of S-phenyl-N-acetylcysteine]20100551
C053003S-phenyl-N-acetylcysteineGSTM1 gene polymorphism affects the abundance of S-phenyl-N-acetylcysteine20100551
C053003S-phenyl-N-acetylcysteineGSTM1 polymorphism affects the abundance of S-phenyl-N-acetylcysteine17056211
C053003S-phenyl-N-acetylcysteine[GSTM1 polymorphism co-treated with Smoke] affects the abundance of S-phenyl-N-acetylcysteine21300142
C053003S-phenyl-N-acetylcysteineGSTT1 gene polymorphism affects the reaction [GSTM1 gene polymorphism affects the abundance of S-phenyl-N-acetylcysteine]20100551
D013148SpironolactoneSpironolactone results in increased expression of GSTM1 mRNA18723825
D020058StyreneGSTM1 gene polymorphism affects the susceptibility to Styrene12717779|1475167
D020058StyreneGSTM1 gene polymorphism promotes the reaction [GSTT1 gene polymorphism results in increased susceptibility to Styrene]12016165
D020058StyreneGSTM1 gene polymorphism results in increased susceptibility to Styrene12016165
D020058StyreneGSTM1 protein affects the reaction [CYP2E1 protein affects the metabolism of Styrene]12464798
C013690styrene oxideGSTM1 protein affects the metabolism of styrene oxide11599931|1768987
C013690styrene oxideGSTM1 protein results in decreased susceptibility to styrene oxide11424177|1469856
C013690styrene oxideGSTM1 protein affects the metabolism of styrene oxide1638515
C013690styrene oxideGSTM1 protein affects the metabolism of [styrene oxide co-treated with Glutathione]2604743
D013442SulfinpyrazoneSulfinpyrazone inhibits the reaction [GSTM1 protein results in decreased susceptibility to Vincristine]15044619
D013448SulfobromophthaleinSulfobromophthalein inhibits the reaction [GSTM1 protein affects the metabolism of Dinitrochlorobenzene]7733673
D013448SulfobromophthaleinSulfobromophthalein results in decreased activity of GSTM1 protein7733673
C014202sulfolithocholic acidsulfolithocholic acid binds to and results in decreased activity of GSTM1 protein3954743
C016766sulforafanGSTM1 gene polymorphism affects the susceptibility to sulforafan15623468
C016766sulforafanGSTM1 protein affects the metabolism of sulforafan7826396
C016766sulforafansulforafan inhibits the reaction [alpha-methylepinine results in increased expression of GSTM1 mRNA]21871945
C016766sulforafansulforafan results in increased expression of GSTM1 protein16905640
C016766sulforafanNFE2L2 protein promotes the reaction [sulforafan results in increased expression of GSTM1 mRNA]20932822
C016766sulforafan[sulforafan co-treated with dibenzoylmethane] results in increased expression of GSTM1 mRNA17942926
C016766sulforafansulforafan inhibits the reaction [fenamidone results in increased expression of GSTM1 mRNA]27029645
C016766sulforafansulforafan results in increased expression of GSTM1 mRNA17942926|1907115
C016766sulforafansulforafan results in increased expression of GSTM1 protein11309284|1930389
C016766sulforafansulforafan results in increased expression of GSTM1 protein18823965
D013457Sulfur CompoundsGSTM1 gene polymorphism affects the susceptibility to Sulfur Compounds15033463
C074269Sunphenon"[3,4,5,3',4'-pentachlorobiphenyl co-treated with Sunphenon] affects the expression of GSTM1 mRNA"24378064
D013481SuperoxidesGSTM1 protein results in decreased susceptibility to Superoxides10661898
C013698tallowtallow affects the expression of GSTM1 mRNA19680557
C061133tamibarotenetamibarotene results in increased expression of GSTM1 mRNA15498508
C003377taxifolintaxifolin results in increased expression of GSTM1 mRNA17541156
D013662TeaTea inhibits the reaction [[Carbon Tetrachloride co-treated with Diethylnitrosamine] results in decreased activity of GSTM1 protein]12725062
D013739Testosterone[Testosterone co-treated with Calcitriol] results in increased expression of GSTM1 mRNA21592394
D013739TestosteroneTestosterone results in increased expression of GSTM1 mRNA21592394
C004648testosterone enanthatetestosterone enanthate affects the expression of GSTM1 mRNA17440010
D013749TetrachlorodibenzodioxinGSTM1 protein affects the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]7585625
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of GSTM1 mRNA12377990
D013749TetrachlorodibenzodioxinAHR protein affects the reaction [Tetrachlorodibenzodioxin results in increased expression of GSTM1 mRNA]22496397
D013749Tetrachlorodibenzodioxin[Iron-Dextran Complex co-treated with Tetrachlorodibenzodioxin] results in increased expression of GSTM1 protein9443932
D013749TetrachlorodibenzodioxinNFE2L2 protein affects the reaction [Tetrachlorodibenzodioxin results in increased expression of GSTM1 mRNA]19474220
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of GSTM1 mRNA20702594|2157046
D013749Tetrachlorodibenzodioxin[Tetrachlorodibenzodioxin binds to AHR protein] which results in increased expression of GSTM1 mRNA16214954
D013749Tetrachlorodibenzodioxin"[Tetrachlorodibenzodioxin co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Diethylhexyl Phthalate co-treated with bisphenol A] results in decreased expression of GSTM1 mRNA"28433925
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of GSTM1 mRNA15034205|1794905
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of GSTM1 protein9443932
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of GSTM1 mRNA20959002
D013844ThiazolesThiazoles results in increased expression of GSTM1 mRNA8951341
D013844ThiazolesThiazoles results in increased expression of GSTM1 protein8951341
D013849ThimerosalGSTM1 affects the susceptibility to Thimerosal11007341
D013853Thioacetamide[Diethylnitrosamine co-treated with Thioacetamide co-treated with Thioctic Acid] results in increased expression of GSTM1 mRNA23830814
D013853Thioacetamide[Diethylnitrosamine co-treated with Thioacetamide] results in increased expression of GSTM1 mRNA23830814|2894339
D013853ThioacetamideDimethyl Sulfoxide inhibits the reaction [Thioacetamide results in decreased expression of GSTM1 protein]12370186
D013853ThioacetamideThioacetamide results in decreased expression of GSTM1 protein12370186
D013853ThioacetamideThioacetamide results in increased expression of GSTM1 mRNA15497818
D008063Thioctic Acid[Dietary Fats co-treated with Thioctic Acid] results in increased expression of GSTM1 mRNA18367378
D008063Thioctic Acid[Diethylnitrosamine co-treated with Thioacetamide co-treated with Thioctic Acid] results in increased expression of GSTM1 mRNA23830814
C009495titanium dioxidetitanium dioxide results in decreased expression of GSTM1 mRNA23557971
D014028Tobacco Smoke PollutionTobacco Smoke Pollution results in increased susceptibility to GSTM1 protein polymorphism23643483
D014028Tobacco Smoke Pollution[APOE gene mutant form affects the susceptibility to Tobacco Smoke Pollution] which results in increased expression of GSTM1 mRNA24096154
D014028Tobacco Smoke PollutionTobacco Smoke Pollution results in increased expression of GSTM1 protein22609517|2731939
C082032tocotrienol, alpha"GSTM1 gene polymorphism affects the susceptibility to [Ascorbic Acid co-treated with tocotrienol, alpha]"15668500
D014050TolueneGSTM1 gene polymorphism affects the susceptibility to Toluene17292523
D014051Toluene 2,4-Diisocyanate"GSTM1 protein polymorphism results in increased susceptibility to Toluene 2,4-Diisocyanate"11927838
D014212TretinoinTretinoin metabolite results in decreased expression of GSTM1 mRNA15982314
D014212TretinoinTretinoin results in increased expression of GSTM1 mRNA15498508
C032910triadimefontriadimefon affects the expression of GSTM1 mRNA17383973
D014230TriazolesTriazoles results in increased expression of GSTM1 mRNA8951341
C010360triethylleadtriethyllead results in increased expression of GSTM1 mRNA9020200
C015559trimellitic anhydridetrimellitic anhydride results in decreased expression of GSTM1 mRNA19042947
C052920trimethylarsine oxidetrimethylarsine oxide results in increased expression of GSTM1 mRNA16436460
C052920trimethylarsine oxidetrimethylarsine oxide results in increased expression of GSTM1 protein16436460
D014303TrinitrotolueneTrinitrotoluene affects the expression of GSTM1 mRNA21346803
C012594triphenyltin chloridetriphenyltin chloride inhibits the reaction [GSTM1 protein affects the metabolism of Dinitrochlorobenzene]7733673
C012594triphenyltin chloridetriphenyltin chloride results in decreased activity of GSTM1 protein7733673
C016805tris(1,3-dichloro-2-propyl)phosphate"tris(1,3-dichloro-2-propyl)phosphate results in decreased expression of GSTM1 mRNA"26179874
D014315TriterpenesTriterpenes promotes the reaction [Piperonyl Butoxide results in increased expression of GSTM1 mRNA]18544911
C057693troglitazoneGSTM1 gene polymorphism affects the susceptibility to troglitazone12732844
C113580U 0126U 0126 affects the reaction [1-Methyl-4-phenylpyridinium affects the expression of GSTM1 mRNA]12710931
D014635Valproic AcidValproic Acid affects the expression of GSTM1 mRNA17292431
D014635Valproic AcidValproic Acid results in increased expression of GSTM1 mRNA17381134
D014638VanadatesVanadates results in decreased expression of GSTM1 mRNA22714537
D001335Vehicle EmissionsGSTM1 mutant form promotes the reaction [Vehicle Emissions results in increased expression of CXCL8 protein]22867088
D001335Vehicle EmissionsGSTM1 mutant form promotes the reaction [Vehicle Emissions results in increased expression of IL1B protein]22867088
D001335Vehicle EmissionsGSTM1 mutant form promotes the reaction [Vehicle Emissions results in increased phosphorylation of AKT1 protein]22867088
D001335Vehicle EmissionsGSTM1 mutant form promotes the reaction [Vehicle Emissions results in increased phosphorylation of MAPK1 protein]22867088
D001335Vehicle EmissionsGSTM1 mutant form promotes the reaction [Vehicle Emissions results in increased phosphorylation of MAPK3 protein]22867088
D001335Vehicle EmissionsNFE2L2 gene mutant form inhibits the reaction [Vehicle Emissions results in increased expression of GSTM1 mRNA]18614404
D001335Vehicle EmissionsVehicle Emissions results in decreased expression of GSTM1 mRNA18307122
D001335Vehicle EmissionsVehicle Emissions results in decreased expression of GSTM1 protein18307122
D001335Vehicle EmissionsVehicle Emissions results in decreased methylation of GSTM1 gene25560391
D001335Vehicle EmissionsVehicle Emissions results in increased expression of GSTM1 mRNA18614404
D001335Vehicle EmissionsVehicle Emissions results in decreased expression of GSTM1 mRNA23905969
D001335Vehicle EmissionsVehicle Emissions results in increased expression of GSTM1 mRNA22352393
C025643vinclozolinvinclozolin affects the expression of GSTM1 mRNA23034163
C025643vinclozolinvinclozolin results in increased expression of GSTM1 mRNA23034163
D014750VincristineGSTM1 gene polymorphism affects the susceptibility to Vincristine15713801
D014750VincristineGSTM1 protein results in decreased susceptibility to Vincristine15044619
D014750VincristineSulfinpyrazone inhibits the reaction [GSTM1 protein results in decreased susceptibility to Vincristine]15044619
D014752Vinyl ChlorideGSTM1 gene polymorphism affects the reaction [XRCC1 gene polymorphism affects the reaction [Vinyl Chloride affects the mutagenesis of TP53 gene]]16097394
D014752Vinyl Chloride[GSTM1 gene polymorphism co-treated with GSTT1 gene polymorphism] results in increased susceptibility to Vinyl Chloride16977343
C029297vinylidene chloridevinylidene chloride results in decreased expression of GSTM1 mRNA26682919
D024483Vitamin K 3Vitamin K 3 results in increased expression of GSTM1 mRNA14610226

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0004364glutathione transferase activity-IDA8373352  
GO:0004364glutathione transferase activity-TAS-  
GO:0019899enzyme binding-IPI8373352  
GO:0042803protein homodimerization activity-IPI8373352  
GO:0043295glutathione binding-IDA8373352  
GO ID GO Term Qualifier Evidence PubMed
GO:0006749glutathione metabolic process-IDA8373352  
GO:0018916nitrobenzene metabolic process-IDA8373352  
GO:0042178xenobiotic catabolic process-IDA8373352  
GO:0070458cellular detoxification of nitrogen compound-IDA8373352  
GO:1901687glutathione derivative biosynthetic process-TAS-  
GO ID GO Term Qualifier Evidence PubMed
GO:0005737cytoplasm-IDA8373352  
GO:0005829cytosol-IDA-  
GO:0005829cytosol-TAS-  
GO:0045171intercellular bridge-IDA-  
KEGG ID KEGG Term
hsa00480Glutathione metabolism
hsa00980Metabolism of xenobiotics by cytochrome P450
hsa00982Drug metabolism - cytochrome P450
Reactome ID Reactome Term Evidence
R-HSA-1430728MetabolismTAS
R-HSA-156580Phase II - Conjugation of compoundsTAS
R-HSA-156590Glutathione conjugationTAS
R-HSA-211859Biological oxidationsTAS

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
11257276Interaction of the glutathione S-transferase genes and cigarette smoking on risk of lower extremity arterial disease: the Atherosclerosis Risk in Communities (ARIC) study. (2001 Feb 15)Li RAtherosclerosis
28397463Colorectal Cancer Carcinogenesis: a Multivariate Genetic Model in a Cohort of Romanian Population. (2017 Apr 1)Procopciuc LMClin Lab
18690546CYP1A2, CYP2D6, GSTM1, GSTP1, and GSTT1 gene polymorphisms in patients with bladder cancer in a Turkish population. (2009)Altayli EInt Urol Nephrol
23840148CYP1A1, GSTM1, GSTT1 and NQO1 polymorphisms and colorectal adenomas in Japanese men. (2013 Jul 7)Hamachi TWorld J Gastroenterol
22809837BPDE-like DNA adduct level in oral tissue may act as a risk biomarker of oral cancer. (2013 Jan)Chuang CYArch Oral Biol
15829318Polymorphisms in genes involved in xenobiotic metabolism and lung cancer risk under the age of 60 years. A pooled study of lung cancer patients in Denmark and Norway. (2005 May)Skuladottir HLung Cancer
11137199Gender differences in genetic susceptibility for lung cancer. (2000 Dec)Dresler CMLung Cancer
8439946Genotype and phenotype of glutathione S-transferase class mu isoenzymes mu and psi in lung cancer patients and controls. (1993 Mar 1)Brockmoller JCancer Res
26600754Prostate cancer and glutathione S-transferase deletions. (2015)Malik SSEXCLI J
15840612Cigarette smoking and colorectal cancer: APC mutations, hMLH1 expression, and GSTM1 and GSTT1 polymorphisms. (2005 May 1)Luchtenborg MAm J Epidemiol
10511265Variations in urinary 1-hydroxypyrene glucuronide in relation to smoking and the modification effects of GSTM1 and GSTT1. (1999 Sep 5)Hong YCToxicol Lett
18261353[Combined effects of genetic polymorphisms in cytochrome P450s and GSTM1 on lung cancer susceptibility]. (2007 Nov 20)Gu YFZhonghua Yi Xue Za Zhi
20847076Genetic susceptibility to asbestos-related fibrotic pleuropulmonary changes. (2011 Sep)Kukkonen MKEur Respir J
15646021Genetic polymorphism of the CYP1A1, CYP2E1, GSTM1 and GSTT1 genes and lung cancer susceptibility in a north indian population. (2004 Nov)Sobti RCMol Cell Biochem
19960570Glutathione-S-transferase (GSTM1, GSTT1) and the risk of gastrointestinal cancer in a Korean population. (2009 Dec 7)Piao JMWorld J Gastroenterol
16273625Interaction models of CYP1A1, GSTM1 polymorphisms and tobacco smoking in intestinal gastric cancer. (2005 Oct 14)Shen JWorld J Gastroenterol
11097350Influence of glutathione S-transferase M1 and T1 genotypes on larynx cancer risk among Korean smokers. (2000 Sep)Hong YJClin Chem Lab Med
18226074Exploiting gene-environment interaction to detect adverse health effects of environmental chemicals on the next generation. (2008 Feb)Kishi RBasic Clin Pharmacol Toxicol
24467372GSTM1-null genotype as a risk factor for sporadic colorectal cancer in a Romanian population. Association with the NAT2-rapid-acetylator phenotype and exposure to environmental factors. (2014 Feb)Procopciuc LMCancer Invest
20957336CYP1A2*1F and GSTM1 alleles are associated with susceptibility to porphyria cutanea tarda. (2011 Mar-Apr)Wickliffe JKMol Med
12050092Incorporating genetic susceptibility feedback into a smoking cessation program for African-American smokers with low income. (2002 Jun)McBride CMCancer Epidemiol Biomarkers Prev
23643483Interactive effects of smoking and glutathione S-transferase polymorphisms on the development of non-alcoholic fatty liver disease. (2013 Jul 4)Oniki KToxicol Lett
12037246Organic solvent exposure, genes, and risk of neuropsychological impairment. (2002 Jun)Dick FQJM
28696897Polymorphisms of xenobiotic metabolizing enzymes in bladder cancer patients of the Semmelweis University Budapest, Hungary. (2017)Ebbinghaus DJ Toxicol Environ Health A
9329644Interactions between genetic predisposition and environmental toxicants for development of lung cancer. (1997)el-Zein REnviron Mol Mutagen
23661016Association between GSTP1, GSTM1 and GSTT1 polymorphisms involved in xenobiotic metabolism and head and neck cancer development. (2013 Jul)Russo AMol Biol Rep
11401922Feasibility of collecting buccal cell DNA by mail in a cohort study. (2001 Jun)Le Marchand LCancer Epidemiol Biomarkers Prev
8988674Glutathione S-transferase and cytochrome-P-450 polymorphism as risk factors for squamous cell carcinoma of the larynx. (1996 Dec)Jahnke VAm J Surg
29111615Glutathione S-transferase genes and the risk of type 2 diabetes mellitus: Role of sexual dimorphism, gene-gene and gene-smoking interactions in disease susceptibility. (2018 May)Azarova IJ Diabetes
9725993Coke oven workers study: the effect of exposure and GSTM1 and NAT2 genotypes on DNA adduct levels in white blood cells and lymphocytes as determined by 32P-postlabelling. (1998 Aug 7)Binkova BMutat Res
24075358GSTA1, GSTM1, GSTP1, and GSTT1 polymorphisms and susceptibility to smoking-related bladder cancer: a case-control study. (2013 Oct)Matic MUrol Oncol
12376511Influence of metabolic genotypes on biomarkers of exposure to 1,3-butadiene in humans. (2002 Oct)Fustinoni SCancer Epidemiol Biomarkers Prev
15093278Cytogenetic biomarkers and genetic polymorphisms. (2004 Apr 1)Norppa HToxicol Lett
8665871Cytogenetic monitoring of occupational exposure to pesticides: characterization of GSTM1, GSTT1, and NAT2 genotypes. (1996)Scarpato REnviron Mol Mutagen
22502660An updated pooled analysis of glutathione S-transferase genotype polymorphisms and risk of adult gliomas. (2012)Yao LAsian Pac J Cancer Prev
14618622Effect of SULT1A1 and NAT2 genetic polymorphism on the association between cigarette smoking and colorectal adenomas. (2004 Jan 1)Tiemersma EWInt J Cancer
9850050Association between lung cancer and microsomal epoxide hydrolase genotypes. (1998 Dec 1)Benhamou SCancer Res
10840461Polymorphisms of N-acetyltransferase 2, glutathione S-transferase mu and theta genes as risk factors of bladder cancer in relation to asthma and tuberculosis. (2000 Jul)Kim WJJ Urol
15223862Glutathione S transferase deficiency and passive smoking increase childhood asthma. (2004 Jul)Kabesch MThorax
16535824[Relationship between GSTM1 and GSTT1 gene polymorphisms and noise induced hearing loss in Chinese workers]. (2005 Nov)Yang MWei Sheng Yan Jiu
18463401CYP1A1, GSTM1, and GSTT1 polymorphisms, smoking, and lung cancer risk in a pooled analysis among Asian populations. (2008 May)Lee KMCancer Epidemiol Biomarkers Prev
11854392A population-based, case-control study of polymorphisms in carcinogen-metabolizing genes, smoking, and pancreatic adenocarcinoma risk. (2002 Feb 20)Duell EJJ Natl Cancer Inst
22234881Copy number variations of GSTT1 and GSTM1, colorectal cancer risk and possible effect modification of cigarette smoking and menopausal hormone therapy. (2012 Sep 1)Rudolph AInt J Cancer
17855160Relationship between the capacity to repair 8-oxoguanine, biomarkers of genotoxicity and individual susceptibility in styrene-exposed workers. (2007 Dec 1)Slyskova JMutat Res
9077484Truncal tumor site is associated with high risk of multiple basal cell carcinoma and is influenced by glutathione S-transferase, GSTT1, and cytochrome P450, CYP1A1 genotypes, and their interaction. (1997 Apr)Lear JTJ Invest Dermatol
10371337Glutathione-S-transferase polymorphisms and risk of squamous-cell carcinoma of the head and neck. (1999 Jun 21)Cheng LInt J Cancer
11984214Glutathione S-transferase mu1 deficiency, cigarette smoking and coronary artery disease. (2002 Feb)Wang XLJ Cardiovasc Risk
21872227Maternal smoking during pregnancy, polymorphic CYP1A1 and GSTM1, and lung-function measures in urban family children. (2011 Nov)Chen XEnviron Res
9804932Chromosomal aberrations, sister-chromatid exchanges, cells with high frequency of SCE, micronuclei and comet assay parameters in 1, 3-butadiene-exposed workers. (1998 Nov 9)Sram RJMutat Res
12296511Cigarette smoking, glutathione-s-transferase M1 and t1 genetic polymorphisms, and breast cancer risk (United States). (2002 Sep)Zheng TCancer Causes Control
9748537Comparison of DNA adduct levels associated with oxidative stress in human pancreas. (1998 Sep 20)Kadlubar FFMutat Res
25603868[Molecular epidemiology study in Xuanwei: the relationship among coal type, genotype and lung cancer risk]. (2015 Jan)Li JZhongguo Fei Ai Za Zhi
10923314[GSTM1 gene polymorphism in patients with head and neck tumors]. (2000 Jun)Gronau SLaryngorhinootologie
23275234Glutathione S-transferase M1 and T1 genotypes and myocardial infarction. (2013 Apr)Cora TMol Biol Rep
24651583Genetic polymorphisms in metabolizing enzymes modifying the association between smoking and inflammatory bowel diseases. (2014 May)Ananthakrishnan ANInflamm Bowel Dis
9255556Interaction between dose and susceptibility to environmental cancer: a short review. (1997 Jun)Hietanen EEnviron Health Perspect
24266295Polymorphisms of genes involved in polycyclic aromatic hydrocarbons' biotransformation and atherosclerosis. (2013)Marinkovic NBiochem Med (Zagreb)
12712736[Glutathione S-transferase GSTM1 and GSTT1 genotypes and susceptibility to lung cancer]. (1999 Jan 30)Lan QWei Sheng Yan Jiu
23845145Risk factors for serious adverse effects of thiopurines in patients with Crohn's disease. (2013 Jul)Mazor YCurr Drug Saf
7917923Progression of cervical intraepithelial neoplasia to cervical cancer: interactions of cytochrome P450 CYP2D6 EM and glutathione s-transferase GSTM1 null genotypes and cigarette smoking. (1994 Oct)Warwick APBr J Cancer
10744635Glutathione S-transferase M1 null genotype is associated with a decreased risk of myocardial infarction. (2000 Apr)Wilson MHFASEB J
15138035Life style, environmental and genetic susceptibility to cervical cancer. (2004 May 20)Au WWToxicology
22330623Association of manganese superoxide dismutase and glutathione S-transferases genotypes with carotid atherosclerosis in patients with diabetes mellitus type 2. (2012 Feb)Santl Letonja MInt Angiol
25348056Joint effect of glutathione S-transferase genotypes and cigarette smoking on idiopathic male infertility. (2015 Nov)Yarosh SLAndrologia
16638627Distribution of glutathione S-transferase M1, P1 and T1 genotypes in different age-groups of Finns without diagnosed cancer. (2006)Voho ACancer Detect Prev
19917083Examination of polymorphic glutathione S-transferase (GST) genes, tobacco smoking and prostate cancer risk among men of African descent: a case-control study. (2009 Nov 16)Lavender NABMC Cancer
21436184Glutathione S-transferase M1 (GSTM1) and glutathione S-transferase T1 (GSTT1) null polymorphisms, smoking, and their interaction in oral cancer: a HuGE review and meta-analysis. (2011 Apr 15)Zhang ZJAm J Epidemiol
17530260Epidemiology of urinary bladder cancer: from tumor development to patient's death. (2007 Jun)Murta-Nascimento CWorld J Urol
16206220A multi-biomarker analysis of DNA damage in automobile painters. (2005 Oct)Testa AEnviron Mol Mutagen
19701675Genetic susceptibility in solvent induced neurobehavioral effects. (2010 Apr)Godderis LNeurotox Res
21359562Modulation of urinary polycyclic aromatic hydrocarbon metabolites by enzyme polymorphisms in workers of the German Human Bitumen Study. (2011 Jun)Rihs HPArch Toxicol
28192769Disorganization at the stage of schizophrenia clinical outcome: Clinical-biological study. (2017 May)Nestsiarovich AEur Psychiatry
20937634Cigarette smoking, genetic variants in carcinogen-metabolizing enzymes, and colorectal cancer risk. (2010 Nov 1)Cleary SPAm J Epidemiol
25040976Susceptibility of lung cancer with polymorphisms of CYP1A1, GSTM1, GSTM3, GSTT1 and GSTP1 genotypes in the population of Inner Mongolia region. (2014)Jiang XYAsian Pac J Cancer Prev
19811334Meta-analysis study of glutathione-S-transferases (GSTM1, GSTP1, and GSTT1) gene polymorphisms and risk of acute myeloid leukemia. (2009 Aug)Das PLeuk Lymphoma
9679751Combined effect of polymorphic GST genes on individual susceptibility to lung cancer. (1998 Aug 12)Saarikoski STInt J Cancer
15141365GSTM1, GSTT1, and GSTP1 genotypes and the genotoxicity of hydroquinone in human lymphocytes. (2004)Silva Mdo CEnviron Mol Mutagen
21445357Effects of GSTM1 in rheumatoid arthritis; results from the Swedish EIRA study. (2011 Mar 22)Lundstrom EPLoS One
24318990GSTM1 null genotype is associated with increased risk of gastric cancer in both ever-smokers and non-smokers: a meta-analysis of case-control studies. (2014 Apr)Gu JTumour Biol
25531380[Relation of polymorphisms of the XPD and GSTM1 genes with susceptibility to hepatocellular carcinoma in Qinghai Tibetans]. (2014 Nov)Zhao JHZhonghua Gan Zang Bing Za Zhi
10935938Impairment of colour vision in workers exposed to organic solvents. (2000 Sep)Semple SOccup Environ Med
23054023Glutathione S-transferase P1 gene polymorphism and bladder cancer susceptibility: an updated analysis. (2013 Jan)Wu KMol Biol Rep
15536330CYP2E1 polymorphism, cigarette smoking, p53 expression, and survival in non-small cell lung cancer: a long term follow-up study. (2004 Dec)Haque AKAppl Immunohistochem Mol Morphol
15927971Increased cardiovascular morbidity and mortality in type 2 diabetes is associated with the glutathione S transferase theta-null genotype: a Go-DARTS study. (2005 Jun 7)Doney ASCirculation
19963114Effect of combined genetic polymorphisms on lung cancer risk in northern Thai women. (2009 Dec)Klinchid JCancer Genet Cytogenet
10223202Decreased expression of glutathione S-transferase M1 in HPV16-transfected human cervical keratinocytes in culture. (1999 Apr)Chen CCarcinogenesis
17953974Inherited susceptibility to bleomycin-induced micronuclei: correlating polymorphisms in GSTT1, GSTM1 and DNA repair genes with mutagen sensitivity. (2008 Feb 1)Angelini SMutat Res
16906563Risk of limb deficiency defects associated with NAT1, NAT2, GSTT1, GSTM1, and NOS3 genetic variants, maternal smoking, and vitamin supplement intake. (2006 Sep 15)Carmichael SLAm J Med Genet A
15495595[Genetic susceptibility and risk of gastric cancer in a human population of Cauca, Colombia]. (2004 Jun)Torres MMBiomedica
17563610Glutathione S-transferases GSTM1 and GSTT1 polymorphisms and asbestosis. (2007 Jun)Franko AJ Occup Environ Med
19102712Glutathione S-transferase T1- and M1-null genotypes and coronary artery disease risk in patients with Type 2 diabetes mellitus. (2009 Jan)Manfredi SPharmacogenomics
23019974[Polymorphism of GSTT1 and GSNM1 glutathione transferase genes in smokers and patients at the early stages of chronic obstructive pulmonary disease]. (2012)Nevzorova VAKlin Med (Mosk)
11920399Smoking and disease severity in rheumatoid arthritis: association with polymorphism at the glutathione S-transferase M1 locus. (2002 Mar)Mattey DLArthritis Rheum
23570881GSTM1, GSTT1, GSTP1, and GSTA1 genetic variants are not associated with coronary artery disease in Taiwan. (2013 Jul 1)Yeh HLGene
7728947Expression and polymorphism of glutathione S-transferase in human lungs: risk factors in smoking-related lung cancer. (1995 Apr)Nakajima TCarcinogenesis
11948486Polycyclic aromatic hydrocarbon-DNA adducts in liver tissues of hepatocellular carcinoma patients and controls. (2002 May 1)Chen SYInt J Cancer
19933708Protein carbonyl levels, glutathione S-transferase polymorphisms and risk of colorectal cancer. (2010 Feb)Yeh CCCarcinogenesis
20029178Glutathione s-transferase m1 and t1 polymorphisms and susceptibility to oxidative damage in healthy korean smokers. (2010)Lee SHAnn Nutr Metab
11352866Hemoglobin adducts and sister chromatid exchanges in hospital workers exposed to ethylene oxide: effects of glutathione S-transferase T1 and M1 genotypes. (2001 May)Yong LCCancer Epidemiol Biomarkers Prev
16614098Is the association between cigarette smoking and breast cancer modified by genotype? A review of epidemiologic studies and meta-analysis. (2006 Apr)Terry PDCancer Epidemiol Biomarkers Prev
8706015Prognostic significance of germ line polymorphisms of the CYP1A1 and glutathione S-transferase genes in patients with non-small cell lung cancer. (1996 Aug 15)Goto ICancer Res
16235998Multiplex PCR with confronting two-pair primers for CYP1A1 Ile462Val, GSTM1, GSTT1, and NQO1 C609T. (2005 Jul-Sep)Kawai SAsian Pac J Cancer Prev
11844594Genetic determinants of lung cancer short-term survival: the role of glutathione-related genes. (2002 Mar)Yang PLung Cancer
20402821Polymorphism of glutathione S-transferase M1 and T1 gene loci in COPD. (2010 Aug)Mehrotra SInt J Immunogenet
10729397Glutathione S-transferase genotype as a susceptibility factor in smoking-related coronary heart disease. (2000 Apr)Li RAtherosclerosis
10435155Polymorphisms of the CYP1A1 and GSTM1 gene involved in oral squamous cell carcinoma in association with a cigarette dose. (1999 Mar)Tanimoto KOral Oncol
21738036Familial bladder cancer and the related genes. (2011 Sep)Hemminki KCurr Opin Urol
12397651Genetic polymorphism in myeloperoxidase but not GSTM1 is associated with risk of lung squamous cell carcinoma in a Chinese population. (2002 Nov 20)Lu WInt J Cancer
12468438CYP1A1*2B (Val) allele is overrepresented in a subgroup of acute myeloid leukemia patients with poor-risk karyotype associated with NRAS mutation, but not associated with FLT3 internal tandem duplication. (2003 Apr 1)Bowen DTBlood
15769360[The relationship between genetic polymorphism of metabolizing enzymes and the genetic susceptibility to lung cancer]. (2004 Dec)Li WYZhonghua Liu Xing Bing Xue Za Zhi
27641673Arginine intake is associated with oxidative stress in a general population. (2017 Jan)Carvalho AMNutrition
22783438Correlation of CYP1A1, GSTP1 and GSTM1 gene polymorphisms and lung cancer risk among smokers. (2012 Jun)Pliarchopoulou KOncol Lett
16504378Does occupational exposure to PAHs, diesel and aromatic amines interact with smoking and metabolic genetic polymorphisms to increase the risk on bladder cancer?; The Belgian case control study on bladder cancer risk. (2007 Jan 8)Kellen ECancer Lett
12419833Genetic polymorphisms of alcohol and aldehyde dehydrogenases and glutathione S-transferase M1 and drinking, smoking, and diet in Japanese men with esophageal squamous cell carcinoma. (2002 Nov)Yokoyama ACarcinogenesis
20391126Functional alterations in the glutathione S-transferase family associated with enhanced occurrence of esophageal carcinoma in China. (2010)Liu RJ Toxicol Environ Health A
19174490Tobacco and estrogen metabolic polymorphisms and risk of non-small cell lung cancer in women. (2009 Apr)Cote MLCarcinogenesis
27911277GSTM1 and GSTT1 polymorphisms are associated with increased bladder cancer risk: Evidence from updated meta-analysis. (2017 Jan 10)Yu COncotarget
18647550Lack of association of GSTT1, GSTM1, GSTO1, GSTP1 and CYP1A1 polymorphisms for susceptibility and outcome in Brazilian prostate cancer patients. (2008)Lima MM JrFolia Biol (Praha)
9434875Combined genetic polymorphism and risk for development of lung cancer. (1997 Nov 28)el-Zein RMutat Res
7788847Transplacental transfer of environmental genotoxins: polycyclic aromatic hydrocarbon-albumin in non-smoking women, and the effect of maternal GSTM1 genotype. (1995 Jun)Autrup HCarcinogenesis
12919719Susceptibility and exposure biomarkers in people exposed to PAHs from diesel exhaust. (2003 Sep 15)Adonis MToxicol Lett
9330622Predisposing genes and increased chromosome aberrations in lung cancer cigarette smokers. (1997 Sep 5)Conforti-Froes NMutat Res
16030123GSTM1, GSTT1, and GSTP1 polymorphisms and risk of advanced colorectal adenoma. (2005 Jul)Moore LECancer Epidemiol Biomarkers Prev
7640212Phenotype of glutathione S-transferase Mu (GSTM1) and susceptibility to malignant melanoma. MMM group. Multidisciplinary Malignant Melanoma Group. (1995 Aug)Lafuente ABr J Cancer
23628324Genetic polymorphisms of CYP2E1, GST, and NAT2 enzymes are not associated with risk of breast cancer in a sample of Lebanese women. (2013 Jul-Aug)Zgheib NKMutat Res
8313538Lung cancer risk of GSTM1 null genotype is dependent on the extent of tobacco smoke exposure. (1994 Feb)Kihara MCarcinogenesis
16625286Joint effect among p53, CYP1A1, GSTM1 polymorphism combinations and smoking on prostate cancer risk: an exploratory genotype-environment interaction study. (2006 May)Quinones LAAsian J Androl
15661231Association of the NAD(P)H: quinone oxidoreductase C609T polymorphism and the risk of cervical cancer in Japanese subjects. (2005 Feb)Niwa YGynecol Oncol
19874347Polymorphism of glutathione S-transferases M1 and T1: susceptibility to solar keratoses in an Italian population. (2010 Oct)Guarneri FClin Exp Dermatol
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