Gene: GSTM3

2947
GST5|GSTB|GSTM3-3|GTM3
glutathione S-transferase mu 3
protein-coding
1p13.3
Ensembl:ENSG00000134202 MIM:138390 Vega:OTTHUMG00000011640 UniprotKB:P21266
NC_000001.11
PubMed
ND
36   
3.799e-1 (AD)  9.353e-1 (ND)   (Frontal_Cortex)
1.222e-1 (AD)  7.789e-1 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
ADH50.766
CPE0.741
CTNNA20.739
CASC40.738
ALDH5A10.735
NEBL0.733
BBS20.726
FAM213A0.725
DDAH10.723
SCP20.72

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
OR4F5-0.623
OR4F29-0.577
TMEM236-0.219
OR6C74-0.217
CETP-0.211
TRPV5-0.204
NANOGNB-0.203
SPOCD1-0.195
TNFRSF13B-0.194
KEL-0.193

Drugs/Compounds

ID Drug Name Drug Type CAS Num Status Role
DB00143GlutathioneSmall Molecule70-18-8Approved|Investigational|NutraceuticalTarget
DB00163Vitamin ESmall Molecule59-02-9Approved|NutraceuticalEnzyme
DB14001alpha-Tocopherol succinateSmall Molecule4345-03-3Approved|NutraceuticalEnzyme
DB14002D-alpha-Tocopherol acetateSmall Molecule58-95-7Approved|NutraceuticalEnzyme
ID Drug Name Action PubMed
C0283281,2-dichloro-4-nitrobenzene"GSTM3 protein affects the metabolism of 1,2-dichloro-4-nitrobenzene"3169012
C0284741,4-bis(2-(3,5-dichloropyridyloxy))benzene"[1,4-bis(2-(3,5-dichloropyridyloxy))benzene results in increased activity of NR1I3 protein] which results in increased expression of GSTM3 mRNA"22496397
C0284741,4-bis(2-(3,5-dichloropyridyloxy))benzene"1,4-bis(2-(3,5-dichloropyridyloxy))benzene results in increased expression of GSTM3 mRNA"18723825|2249639
C0284741,4-bis(2-(3,5-dichloropyridyloxy))benzene"CTNNB1 protein affects the reaction [1,4-bis(2-(3,5-dichloropyridyloxy))benzene results in increased expression of GSTM3 mRNA]"23578392
C0284741,4-bis(2-(3,5-dichloropyridyloxy))benzene"NR1I3 protein affects the reaction [1,4-bis(2-(3,5-dichloropyridyloxy))benzene results in increased expression of GSTM3 mRNA]"22496397
C0426301-chloro-2,4-dinitrobenzene-glutathione conjugate"GSTM3 protein affects the metabolism of 1-chloro-2,4-dinitrobenzene-glutathione conjugate"11684093
C0140242,4,5,2',4',5'-hexachlorobiphenyl"[2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Diethylnitrosamine] results in increased expression of GSTM3 mRNA"23457121
C0140242,4,5,2',4',5'-hexachlorobiphenyl"[Tetrachlorodibenzodioxin co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Diethylhexyl Phthalate co-treated with bisphenol A] results in decreased expression of GSTM3 mRNA"28433925
C0164032,4-dinitrotoluene"2,4-dinitrotoluene affects the expression of GSTM3 mRNA"21346803
C0094972-(4-toluidino)-6-naphthalenesulfonic acid2-(4-toluidino)-6-naphthalenesulfonic acid binds to GSTM3 protein7725348
C0235142,6-dinitrotoluene"2,6-dinitrotoluene affects the expression of GSTM3 mRNA"21346803
C0131662-nonenalGSTM3 protein polymorphism results in decreased metabolism of 2-nonenal15247628
C0131662-nonenalGSTM3 protein polymorphism results in increased metabolism of 2-nonenal15247628
C5724913-(2-hydroxy-4-(2-methylnonan-2-yl)phenyl)cyclohexan-1-ol3-(2-hydroxy-4-(2-methylnonan-2-yl)phenyl)cyclohexan-1-ol results in increased expression of GSTM3 protein26194647
C0230353,4,5,3',4'-pentachlorobiphenyl"3,4,5,3',4'-pentachlorobiphenyl results in increased expression of GSTM3 mRNA"24378064
C0230353,4,5,3',4'-pentachlorobiphenyl"Sunphenon promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of GSTM3 mRNA]"24378064
C0230353,4,5,3',4'-pentachlorobiphenyl"3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of GSTM3 mRNA"23196670
C0502243,5,5-trimethylhexanoylferrocene"3,5,5-trimethylhexanoylferrocene results in increased expression of GSTM3 protein"22649188
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of GSTM3 mRNA"27188386
C0275764-hydroxy-2-nonenal[GSTM1 protein binds to GSTM3 protein] which affects the metabolism of 4-hydroxy-2-nonenal analog11256969
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of GSTM3 mRNA"27188386
D000082AcetaminophenAcetaminophen results in decreased expression of GSTM3 mRNA16611625
D000082AcetaminophenAcetaminophen results in decreased expression of GSTM3 mRNA17522070
D016604Aflatoxin B1Aflatoxin B1 results in decreased expression of GSTM3 mRNA19770486
D000447AldehydesAldehydes results in increased expression of GSTM3 mRNA25014914
C038491allyl sulfideallyl sulfide results in increased expression of GSTM3 mRNA18723825
D000517alpha-Chlorohydrinalpha-Chlorohydrin analog results in decreased expression of GSTM3 protein26597043
D000517alpha-Chlorohydrinalpha-Chlorohydrin results in increased expression of GSTM3 protein26072098
D006710Homocysteine[Methionine deficiency co-treated with Homocysteine] affects the expression of GSTM3 protein17116298
D000643Ammonium ChlorideAmmonium Chloride affects the expression of GSTM3 mRNA16483693
C030419andrographolide[andrographolide co-treated with beta-Naphthoflavone] results in increased expression of GSTM3 mRNA19737545
C030419andrographolideandrographolide results in increased expression of GSTM3 mRNA19737545
C000228aristolochic acid Iaristolochic acid I results in increased expression of GSTM3 mRNA17483316
D034341Aristolochic AcidsAristolochic Acids results in increased expression of GSTM3 mRNA21834575
D001151ArsenicArsenic affects the methylation of GSTM3 gene25304211
D001151ArsenicArsenic results in increased expression of GSTM3 mRNA19945496
C006632arsenic trioxidearsenic trioxide results in increased expression of GSTM3 mRNA22521957
D001194AsbestosAsbestos affects the expression of GSTM3 protein7614465
D017636Asbestos, Amphibole"Asbestos, Amphibole affects the expression of GSTM3 protein"20855422
D001280Atrazine[Atrazine co-treated with Chlorpyrifos co-treated with Endosulfan] results in increased expression of GSTM3 mRNA22515965
D019324beta-Naphthoflavone[andrographolide co-treated with beta-Naphthoflavone] results in increased expression of GSTM3 mRNA19737545
D019324beta-Naphthoflavonebeta-Naphthoflavone results in increased expression of GSTM3 protein9794803
D001564Benzo(a)pyreneBenzo(a)pyrene results in decreased expression of GSTM3 protein22138271
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of GSTM3 mRNA20064835
D001564Benzo(a)pyreneMethionine inhibits the reaction [Benzo(a)pyrene results in decreased expression of GSTM3 protein]22138271
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of GSTM3 mRNA21569818|2196490
C031403benzyl isothiocyanatebenzyl isothiocyanate results in increased expression of GSTM3 protein9794803
C072553benzyloxycarbonylleucyl-leucyl-leucine aldehydebenzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of GSTM3 mRNA20061341
C038328BEP protocolBEP protocol results in increased expression of GSTM3 mRNA23200778
D004958EstradiolEstradiol results in increased expression of GSTM3 mRNA11331657
D004958EstradiolEstradiol results in decreased expression of GSTM3 mRNA14664709
D004958EstradiolEstradiol results in decreased expression of GSTM3 mRNA17522070
C452139BIRB 796BIRB 796 results in increased expression of GSTM3 mRNA21328587
C006780bisphenol Abisphenol A affects the expression of GSTM3 mRNA21786754
C006780bisphenol A"[Tetrachlorodibenzodioxin co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Diethylhexyl Phthalate co-treated with bisphenol A] results in decreased expression of GSTM3 mRNA"28433925
C006780bisphenol Abisphenol A affects the expression of GSTM3 mRNA25181051
C006780bisphenol Abisphenol A results in increased expression of GSTM3 mRNA26794494
C000611646bisphenol F[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of GSTM3 mRNA28628672
D002083Butylated HydroxyanisoleButylated Hydroxyanisole results in increased expression of GSTM3 mRNA18723825|6822548
D002083Butylated HydroxyanisoleButylated Hydroxyanisole results in increased expression of GSTM3 protein11991805
D002083Butylated HydroxyanisoleButylated Hydroxyanisole results in increased expression of GSTM3 protein9794803
C018475butyraldehydebutyraldehyde results in increased expression of GSTM3 mRNA26079696
D002104CadmiumCadmium results in increased expression of GSTM3 mRNA24376830
D019256Cadmium ChlorideCadmium Chloride results in increased expression of GSTM3 protein24527689
D002251Carbon TetrachlorideCarbon Tetrachloride results in increased expression of GSTM3 mRNA27339419
D002251Carbon TetrachloridePLG gene mutant form promotes the reaction [Carbon Tetrachloride results in increased expression of GSTM3 mRNA]16006527
D002251Carbon TetrachlorideCarbon Tetrachloride results in decreased expression of GSTM3 mRNA17522070
D002251Carbon TetrachlorideCarbon Tetrachloride results in increased expression of GSTM3 mRNA16239168
D002259Carbonyl Cyanide p-TrifluoromethoxyphenylhydrazoneCarbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of GSTM3 mRNA16039398
D002330CarmustineGSTM3 protein affects the metabolism of Carmustine15247628
D002330CarmustineGSTM3 protein results in decreased nitrosation of and results in decreased activity of Carmustine8395980
D002330CarmustineGSTM3 protein results in decreased nitrosation of Carmustine11841793
D002725ChloroformChloroform results in decreased expression of GSTM3 mRNA17522070
D002737ChloropreneChloroprene results in increased expression of GSTM3 mRNA23125180
D004390Chlorpyrifos[Atrazine co-treated with Chlorpyrifos co-treated with Endosulfan] results in increased expression of GSTM3 mRNA22515965
D004390ChlorpyrifosChlorpyrifos results in decreased expression of GSTM3 mRNA17452286
D019826Cholic AcidCholic Acid results in increased expression of GSTM3 mRNA17521389
D002994ClofibrateClofibrate results in increased expression of GSTM3 mRNA22496397
D002994ClofibratePPARA protein affects the reaction [Clofibrate results in increased expression of GSTM3 mRNA]22496397
D002995Clofibric AcidClofibric Acid affects the expression of GSTM3 mRNA17602206
D003035CobaltCobalt results in increased expression of GSTM3 mRNA22147119
D003300Copper[Copper co-treated with Diethylnitrosamine co-treated with Iron] results in increased expression of GSTM3 mRNA20302851
D003300Copper[Copper co-treated with Diethylnitrosamine] results in increased expression of GSTM3 mRNA20302851
C030123coumarincoumarin results in increased expression of GSTM3 protein9794803
C007164cumene hydroperoxideGSTM3 protein polymorphism results in decreased metabolism of cumene hydroperoxide15247628
C007164cumene hydroperoxideGSTM3 protein polymorphism results in increased metabolism of cumene hydroperoxide15247628
C007164cumene hydroperoxideGSTM3 protein affects the metabolism of cumene hydroperoxide11684093
C057862cyanoginosin LRcyanoginosin LR results in increased expression of GSTM3 mRNA17654400
D016572CyclosporineCyclosporine results in decreased expression of GSTM3 mRNA25562108|2798913
D016572CyclosporineCyclosporine results in decreased expression of GSTM3 mRNA19770486
C089595cylindrospermopsincylindrospermopsin results in increased expression of GSTM3 mRNA23726867
C093628cyproconazolecyproconazole results in increased expression of GSTM3 mRNA22334560|2397080
C014347decitabine[decitabine affects the methylation of GSTM3 promoter] which affects the expression of GSTM3 mRNA18664505|1866450
D003907Dexamethasone[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of GSTM3 mRNA28628672
D003907DexamethasoneDexamethasone results in increased expression of GSTM3 mRNA18723825
D003907DexamethasoneDexamethasone results in decreased expression of GSTM3 mRNA17522070
D003976DiazinonDiazinon results in increased methylation of GSTM3 gene22964155
D003976DiazinonDiazinon results in decreased expression of GSTM3 mRNA17452286|1944049
C061481dibenzoylmethanedibenzoylmethane results in increased expression of GSTM3 mRNA17942926
C061481dibenzoylmethane[sulforafan co-treated with dibenzoylmethane] results in increased expression of GSTM3 mRNA17942926
D003999Dichloroacetic AcidDichloroacetic Acid results in increased expression of GSTM3 mRNA28962523
D002945CisplatinCisplatin results in increased expression of GSTM3 mRNA27594783
D002945CisplatinGSTM3 gene polymorphism affects the susceptibility to Cisplatin11081456
D002945CisplatinGSTM3 protein affects the susceptibility to Cisplatin16217747
D004008DiclofenacDiclofenac results in increased expression of GSTM3 mRNA26934552
C000944dicrotophosdicrotophos results in decreased expression of GSTM3 mRNA28302478
C121718dicyclanildicyclanil results in increased expression of GSTM3 mRNA15664270
D004026DieldrinDieldrin affects the expression of GSTM3 mRNA19440498
D004041Dietary FatsDietary Fats affects the expression of GSTM3 mRNA19680557
D004041Dietary Fats[Dietary Fats co-treated with Dietary Sucrose] results in decreased expression of GSTM3 mRNA28433925
D004041Dietary FatsDietary Fats results in increased expression of GSTM3 mRNA25016146
D004042Dietary Fats, Unsaturated"[perfluorooctanoic acid co-treated with Dietary Fats, Unsaturated] results in increased expression of GSTM3 mRNA"23626681
D019422Dietary Sucrose[Dietary Fats co-treated with Dietary Sucrose] results in decreased expression of GSTM3 mRNA28433925
D004051Diethylhexyl PhthalateDiethylhexyl Phthalate results in increased expression of GSTM3 mRNA19850644
D004051Diethylhexyl PhthalatePPARA protein inhibits the reaction [Diethylhexyl Phthalate results in increased expression of GSTM3 mRNA]19850644
D004051Diethylhexyl Phthalate"[Tetrachlorodibenzodioxin co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Diethylhexyl Phthalate co-treated with bisphenol A] results in decreased expression of GSTM3 mRNA"28433925
D004052Diethylnitrosamine"[2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Diethylnitrosamine] results in increased expression of GSTM3 mRNA"23457121
D004052Diethylnitrosamine[Diethylnitrosamine co-treated with kojic acid] results in increased expression of GSTM3 mRNA17917374
D004052Diethylnitrosamine[Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of GSTM3 mRNA24535843
D004052Diethylnitrosamine[Copper co-treated with Diethylnitrosamine co-treated with Iron] results in increased expression of GSTM3 mRNA20302851
D004052Diethylnitrosamine[Copper co-treated with Diethylnitrosamine] results in increased expression of GSTM3 mRNA20302851
D004052Diethylnitrosamine[Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of GSTM3 mRNA18544905
D004052Diethylnitrosamine[Diethylnitrosamine co-treated with kojic acid] results in increased expression of GSTM3 mRNA18544905
D004052Diethylnitrosamine[Diethylnitrosamine co-treated with Thioacetamide] results in decreased expression of GSTM3 mRNA28943392
D004052DiethylnitrosamineDiethylnitrosamine results in decreased expression of GSTM3 mRNA19638242
D004052DiethylnitrosamineDiethylnitrosamine results in increased expression of GSTM3 mRNA14965361
D004052Diethylnitrosamine[Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of GSTM3 mRNA18253720|1877588
D004052Diethylnitrosamine[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of GSTM3 mRNA22129741
D004052Diethylnitrosamine[Orphenadrine co-treated with Diethylnitrosamine] results in increased expression of GSTM3 mRNA23665939
D004054DiethylstilbestrolDiethylstilbestrol results in increased expression of GSTM3 mRNA11331657
C472511dimethylarsinous aciddimethylarsinous acid results in increased expression of GSTM3 mRNA20886546
D0151279,10-Dimethyl-1,2-benzanthracene"9,10-Dimethyl-1,2-benzanthracene results in decreased expression of GSTM3 mRNA"22485181
D004137DinitrochlorobenzeneGSTM3 protein affects the metabolism of Dinitrochlorobenzene9545290
D004137DinitrochlorobenzeneGSTM3 protein polymorphism results in decreased metabolism of Dinitrochlorobenzene15247628
D004137DinitrochlorobenzeneGSTM3 protein polymorphism results in increased metabolism of Dinitrochlorobenzene15247628
D004137DinitrochlorobenzeneDinitrochlorobenzene results in increased expression of GSTM3 protein9794801
D004137DinitrochlorobenzeneGSTM3 protein affects the metabolism of Dinitrochlorobenzene3169012
C051904dinophysistoxin 1dinophysistoxin 1 results in increased expression of GSTM3 mRNA28939011
D004281Docosahexaenoic AcidsPPARA protein promotes the reaction [Docosahexaenoic Acids results in increased expression of GSTM3 mRNA]18489776
D004317DoxorubicinDoxorubicin results in increased expression of GSTM3 mRNA26873546
D004317DoxorubicinDoxorubicin results in increased oxidation of GSTM3 protein28818578
D004365Drugs, Chinese Herbal"Drugs, Chinese Herbal results in increased expression of GSTM3 mRNA"23262642
D004391DustDust results in increased expression of GSTM3 mRNA17805423
D015118Eicosapentaenoic AcidPPARA protein promotes the reaction [Eicosapentaenoic Acid results in increased expression of GSTM3 mRNA]18489776
D004642EmodinEmodin results in decreased expression of GSTM3 mRNA16045814
D004726Endosulfan[Atrazine co-treated with Chlorpyrifos co-treated with Endosulfan] results in increased expression of GSTM3 mRNA22515965
D004726EndosulfanEndosulfan results in increased expression of GSTM3 mRNA22515965
D004791Enzyme Inhibitors[Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation of GSTM3 protein23301498
C109476epoxiconazoleepoxiconazole results in increased expression of GSTM3 mRNA22334560|2397080
D004918Erythromycin EstolateErythromycin Estolate results in decreased expression of GSTM3 mRNA17522070
C010452estradiol-17 beta-benzoateestradiol-17 beta-benzoate results in decreased expression of GSTM3 mRNA15972882
C015854estradiol valerateestradiol valerate results in decreased expression of GSTM3 mRNA15972882
D000431EthanolEthanol results in increased expression of GSTM3 mRNA19167417
D000431EthanolEthanol results in increased expression of GSTM3 mRNA16098508
D004997Ethinyl EstradiolEthinyl Estradiol affects the expression of GSTM3 mRNA17555576
D004997Ethinyl EstradiolEthinyl Estradiol results in decreased expression of GSTM3 mRNA17942748
D004997Ethinyl Estradiol[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in decreased expression of GSTM3 mRNA17942748
D004997Ethinyl EstradiolEthinyl Estradiol results in decreased expression of GSTM3 mRNA15576828|1583489
D005015EthoxyquinEthoxyquin results in increased expression of GSTM3 mRNA18723825
D005015EthoxyquinEthoxyquin results in increased expression of GSTM3 protein9794803
C024565ethylene dichlorideethylene dichloride results in decreased expression of GSTM3 mRNA28189721
D011345Fenofibrate[Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of GSTM3 mRNA18253720|1877588
D011345FenofibrateFenofibrate results in decreased expression of GSTM3 mRNA18775883
D005419FlavonoidsFlavonoids results in decreased expression of GSTM3 mRNA18035473
D005485FlutamideFlutamide results in increased expression of GSTM3 mRNA24136188
C056933fumonisin B1fumonisin B1 results in increased expression of GSTM3 mRNA16221962
C039281furanfuran results in increased expression of GSTM3 mRNA20194422
D005907GliclazideGliclazide inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of GSTM3 mRNA]21439372
D005978GlutathioneGSTM3 protein affects the metabolism of Glutathione9545290
D006108GraphiteGraphite results in decreased expression of GSTM3 protein22157353
C412815GW 4064GW 4064 results in increased expression of GSTM3 mRNA26655953
D017313FenretinideFenretinide results in increased expression of GSTM3 mRNA28973697
C016517indole-3-carbinolindole-3-carbinol affects the expression of GSTM3 mRNA21396975
C016517indole-3-carbinol[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of GSTM3 mRNA22129741
C016517indole-3-carbinol[indole-3-carbinol co-treated with Phenobarbital] results in increased expression of GSTM3 mRNA24418717
C016517indole-3-carbinolindole-3-carbinol results in increased expression of GSTM3 mRNA24418717
C016517indole-3-carbinolindole-3-carbinol results in increased expression of GSTM3 protein9794803
D007213Indomethacin[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of GSTM3 mRNA28628672
D015759Ionomycin[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of GSTM3 mRNA25613284
D007501Iron[Copper co-treated with Diethylnitrosamine co-treated with Iron] results in increased expression of GSTM3 mRNA20302851
D0150561-Methyl-3-isobutylxanthine[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of GSTM3 mRNA28628672
C410337K 7174K 7174 results in decreased expression of GSTM3 mRNA24086573
D007657Ketone BodiesKetone Bodies results in increased expression of GSTM3 mRNA16807920
C011890kojic acid[Diethylnitrosamine co-treated with kojic acid] results in increased expression of GSTM3 mRNA17917374
C011890kojic acid[Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of GSTM3 mRNA18544905
C011890kojic acid[Diethylnitrosamine co-treated with kojic acid] results in increased expression of GSTM3 mRNA18544905
D008070LipopolysaccharidesLipopolysaccharides results in decreased expression of GSTM3 mRNA27339419
D008094LithiumLithium results in increased expression of GSTM3 mRNA18082333
D018021Lithium Chloride[Lithium Chloride results in increased activity of CTNNB1 protein] which results in increased expression of GSTM3 mRNA20118494
D058185Magnetite NanoparticlesMagnetite Nanoparticles affects the expression of GSTM3 mRNA25532727
D017258Medroxyprogesterone AcetateMedroxyprogesterone Acetate results in increased expression of GSTM3 mRNA18497975
D008528Mefenamic AcidGSTM3 protein results in increased glutathionylation of Mefenamic Acid analog25372302
D008628MercuryMercury results in increased expression of GSTM3 mRNA24788667
D008715Methionine[Methionine deficiency co-treated with Homocysteine] affects the expression of GSTM3 protein17116298
D008715MethionineMethionine inhibits the reaction [Benzo(a)pyrene results in decreased expression of GSTM3 protein]22138271
C004925methylmercuric chloridemethylmercuric chloride results in increased expression of GSTM3 mRNA23103053
D052998MicrocystinsMicrocystins affects the expression of GSTM3 mRNA19790251
D052998MicrocystinsMicrocystins results in decreased expression of GSTM3 mRNA19790251
C540575MK2i peptide[TGFB1 protein co-treated with MK2i peptide] results in decreased expression of GSTM3 protein20864298
D016686Monocrotaline[Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of GSTM3 mRNA21224054
C406082monomethylarsonous acidmonomethylarsonous acid results in increased expression of GSTM3 mRNA20886546|2210804
C583365N-(2-(1,1'-bicyclopropyl)-2-ylphenyl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide"N-(2-(1,1'-bicyclopropyl)-2-ylphenyl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide results in increased expression of GSTM3 mRNA"29244179
D009270NaloxoneNaloxone results in decreased expression of GSTM3 mRNA17522070
D037742Nanotubes, Carbon"Nanotubes, Carbon affects the expression of GSTM3 protein"22001959
D037742Nanotubes, Carbon"Nanotubes, Carbon results in decreased expression of GSTM3 protein"22157353
D037742Nanotubes, Carbon"Nanotubes, Carbon analog results in decreased expression of GSTM3 mRNA"25554681|2562005
D037742Nanotubes, Carbon"Nanotubes, Carbon results in decreased expression of GSTM3 mRNA"25554681|2562005
D0150581-Naphthylisothiocyanate1-Naphthylisothiocyanate results in decreased expression of GSTM3 mRNA17522070
D009532NickelNickel affects the expression of GSTM3 mRNA14575637
D009532NickelNickel results in decreased expression of GSTM3 mRNA24768652|2558310
D009532Nickeltrichostatin A inhibits the reaction [Nickel affects the expression of GSTM3 mRNA]14575637
D009532NickelNickel affects the expression of GSTM3 mRNA19440498
C014707nitrosobenzylmethylaminenitrosobenzylmethylamine results in decreased expression of GSTM3 mRNA17616710
C025589ochratoxin Aochratoxin A results in increased acetylation of GSTM3 promoter29098329
C025589ochratoxin A[ochratoxin A results in increased acetylation of GSTM3 promoter] which results in increased expression of GSTM3 mRNA29098329|2909832
C025589ochratoxin Aochratoxin A results in increased expression of GSTM3 mRNA29098329
D019319Okadaic AcidOkadaic Acid results in increased expression of GSTM3 mRNA28939011
D000069463Olive OilOlive Oil analog affects the expression of GSTM3 mRNA17349074
C026209oltiprazNFE2L2 protein affects the reaction [oltipraz results in increased expression of GSTM3 mRNA]22496397
C026209oltipraz[oltipraz results in increased activity of NFE2L2 protein] which results in increased expression of GSTM3 mRNA22496397
C026209oltiprazoltipraz results in increased expression of GSTM3 mRNA18723825|2249639
C026209oltiprazoltipraz results in increased expression of GSTM3 protein9794803
D009966OrphenadrineOrphenadrine affects the expression of GSTM3 mRNA23665940
D009966Orphenadrine[Orphenadrine co-treated with Diethylnitrosamine] results in increased expression of GSTM3 mRNA23665939
D009966Orphenadrine[Phenobarbital co-treated with Orphenadrine] affects the expression of GSTM3 mRNA23665940
D010126OzoneOzone results in decreased expression of GSTM3 mRNA12763052
D000073878Palm OilPalm Oil affects the expression of GSTM3 mRNA19680557
D010269ParaquatParaquat results in increased expression of GSTM3 mRNA20883675
D010269ParaquatParaquat results in increased expression of GSTM3 mRNA16128001
D052638Particulate MatterParticulate Matter results in increased expression of GSTM3 mRNA18952161
D010396PenicillaminePenicillamine results in increased expression of GSTM3 mRNA22843330
D010416PentachlorophenolPentachlorophenol results in increased expression of GSTM3 mRNA23892564
C046012pentanalpentanal results in increased expression of GSTM3 mRNA26079696
C471071perfluorohexanesulfonic acidperfluorohexanesulfonic acid results in increased expression of GSTM3 mRNA28558994
C101816perfluoro-n-nonanoic acidperfluoro-n-nonanoic acid results in decreased expression of GSTM3 mRNA21984479
C584865perfluorononanoic acidperfluorononanoic acid results in increased expression of GSTM3 mRNA28558994
C076994perfluorooctane sulfonic acidNR1H3 gene mutant form inhibits the reaction [perfluorooctane sulfonic acid results in increased expression of GSTM3 mRNA]25949234
C076994perfluorooctane sulfonic acidperfluorooctane sulfonic acid affects the expression of GSTM3 mRNA19429403
C076994perfluorooctane sulfonic acidperfluorooctane sulfonic acid results in decreased expression of GSTM3 mRNA26300304
C076994perfluorooctane sulfonic acidperfluorooctane sulfonic acid results in increased expression of GSTM3 mRNA20936131|2594923
C023036perfluorooctanoic acid[NR1H3 gene mutant form results in increased susceptibility to perfluorooctanoic acid] which results in increased expression of GSTM3 mRNA25949234
C023036perfluorooctanoic acidperfluorooctanoic acid affects the expression of GSTM3 mRNA18281256|1942940
C023036perfluorooctanoic acid"[perfluorooctanoic acid co-treated with Dietary Fats, Unsaturated] results in increased expression of GSTM3 mRNA"23626681
C023036perfluorooctanoic acid[perfluorooctanoic acid co-treated with PPARA] results in decreased expression of GSTM3 mRNA20118188
C023036perfluorooctanoic acidperfluorooctanoic acid results in increased expression of GSTM3 mRNA18281256|2011818
C023036perfluorooctanoic acidPPARA protein inhibits the reaction [perfluorooctanoic acid results in increased expression of GSTM3 mRNA]18281256
D015232DinoprostoneGSTM3 protein affects the chemical synthesis of Dinoprostone10905636
D044262Prostaglandin H2GSTM3 protein affects the metabolism of Prostaglandin H210905636
D010634Phenobarbital[Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of GSTM3 mRNA24535843
D010634PhenobarbitalNR1I3 protein affects the reaction [Phenobarbital results in increased expression of GSTM3 mRNA]19482888
D010634Phenobarbital[Phenobarbital co-treated with CTNNB1 protein mutant form] results in increased expression of GSTM3 mRNA20118494
D010634PhenobarbitalPhenobarbital results in increased expression of GSTM3 mRNA18723825|1927001
D010634Phenobarbital[indole-3-carbinol co-treated with Phenobarbital] results in increased expression of GSTM3 mRNA24418717
D010634PhenobarbitalPhenobarbital affects the expression of GSTM3 mRNA23665940|2402578
D010634Phenobarbital[Phenobarbital co-treated with Orphenadrine] affects the expression of GSTM3 mRNA23665940
D010634PhenobarbitalPhenobarbital results in increased expression of GSTM3 mRNA24418717
D010634PhenobarbitalPhenobarbital results in increased expression of GSTM3 protein9794803
D010634PhenobarbitalPiperonyl Butoxide affects the reaction [Phenobarbital affects the expression of GSTM3 mRNA]24025784
D010656PhenylephrinePhenylephrine results in decreased expression of GSTM3 mRNA18158353
D010672Phenytoin[Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of GSTM3 mRNA21224054
D010882Piperonyl ButoxidePiperonyl Butoxide affects the reaction [Phenobarbital affects the expression of GSTM3 mRNA]24025784
D010882Piperonyl ButoxidePiperonyl Butoxide results in increased expression of GSTM3 mRNA18544911|2248451
C006253pirinixic acidpirinixic acid results in decreased expression of GSTM3 mRNA16221962|1742611
D010936Plant ExtractsPlant Extracts results in increased expression of GSTM3 mRNA23262642
D011084Polycyclic Aromatic HydrocarbonsGSTM3 protein polymorphism results in increased susceptibility to Polycyclic Aromatic Hydrocarbons11289100|1174033
D059808PolyphenolsPolyphenols results in decreased expression of GSTM3 mRNA16293270
D011285Pregnenolone CarbonitrileNR1I2 protein affects the reaction [Pregnenolone Carbonitrile results in increased expression of GSTM3 mRNA]22496397
D011285Pregnenolone Carbonitrile[Pregnenolone Carbonitrile results in increased activity of NR1I2 protein] which results in increased expression of GSTM3 mRNA22496397
D011285Pregnenolone CarbonitrilePregnenolone Carbonitrile results in increased expression of GSTM3 mRNA18723825|2249639
C045950propiconazoleNR1H3 gene mutant form promotes the reaction [propiconazole results in increased expression of GSTM3 mRNA]25949234
C045950propiconazolepropiconazole results in increased expression of GSTM3 mRNA21278054|2233456
C045950propiconazolepropiconazole results in increased expression of GSTM3 mRNA16643972
C005556propionaldehydepropionaldehyde results in increased expression of GSTM3 mRNA26079696
D011458Prostaglandins EGSTM3 protein affects the chemical synthesis of Prostaglandins E10905636
C030984pyrenepyrene results in increased expression of GSTM3 mRNA26160115
C010423pyrithione zincpyrithione zinc results in increased expression of GSTM3 mRNA21424779
D011794QuercetinQuercetin results in decreased expression of GSTM3 mRNA16455785
D011802QuinidineQuinidine results in decreased expression of GSTM3 mRNA17522070
C059514resveratrolresveratrol inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of GSTM3 mRNA]21439372
D012293Rifampin[Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of GSTM3 mRNA21224054
D012312RitodrineRitodrine results in increased expression of GSTM3 mRNA23370008
D012822Silicon DioxideSilicon Dioxide analog results in decreased expression of GSTM3 mRNA25895662
C017947sodium arsenitesodium arsenite results in increased expression of GSTM3 mRNA20886546
C017947sodium arsenitesodium arsenite affects the expression of GSTM3 mRNA16507464
D0150862,6-Dichloroindophenol"[2,6-Dichloroindophenol co-treated with NQO1 protein polymorphism] results in increased expression of GSTM3 mRNA"21034357
D018038Sodium SeleniteSodium Selenite results in increased expression of GSTM3 mRNA24383545
D012999SomanSoman results in decreased expression of GSTM3 mRNA19281266
D053260SootSoot results in decreased expression of GSTM3 mRNA22461453
D053260SootSoot results in decreased expression of GSTM3 mRNA21914721
D013148SpironolactoneSpironolactone results in increased expression of GSTM3 mRNA18723825
C025906stilbene oxidestilbene oxide results in increased expression of GSTM3 protein9794803
D013311StreptozocinGliclazide inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of GSTM3 mRNA]21439372
D013311Streptozocinresveratrol inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of GSTM3 mRNA]21439372
D013311Streptozocin[Streptozocin co-treated with Niacinamide] results in decreased expression of GSTM3 mRNA21439372
C016766sulforafan[sulforafan co-treated with dibenzoylmethane] results in increased expression of GSTM3 mRNA17942926
C016766sulforafansulforafan results in increased expression of GSTM3 mRNA17942926
C074269Sunphenon"Sunphenon promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of GSTM3 mRNA]"24378064
C446685systhanesysthane results in increased expression of GSTM3 mRNA23970803
C446685systhanesysthane results in increased expression of GSTM3 mRNA16643972
C013698tallowtallow affects the expression of GSTM3 mRNA19680557
D013629TamoxifenTamoxifen affects the expression of GSTM3 mRNA17555576
C030141taurine-ursodeoxycholate conjugatetaurine-ursodeoxycholate conjugate inhibits the reaction [LEP gene mutant form results in increased expression of GSTM3 mRNA]21079772
C031655tauroursodeoxycholic acidtauroursodeoxycholic acid results in decreased expression of GSTM3 mRNA15885361
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased expression of GSTM3 mRNA16039398
D013749TetrachlorodibenzodioxinAHR protein affects the reaction [Tetrachlorodibenzodioxin results in increased expression of GSTM3 mRNA]22496397
D013749TetrachlorodibenzodioxinNFE2L2 protein affects the reaction [Tetrachlorodibenzodioxin results in increased expression of GSTM3 mRNA]19474220
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of GSTM3 mRNA24680724|2637764
D013749Tetrachlorodibenzodioxin[Tetrachlorodibenzodioxin binds to AHR protein] which results in increased expression of GSTM3 mRNA16214954
D013749Tetrachlorodibenzodioxin"[Tetrachlorodibenzodioxin co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Diethylhexyl Phthalate co-treated with bisphenol A] results in decreased expression of GSTM3 mRNA"28433925
D013749Tetrachlorodibenzodioxin[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in decreased expression of GSTM3 mRNA17942748
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased expression of GSTM3 mRNA19465110
D013749Tetrachlorodibenzodioxin[Tetrachlorodibenzodioxin results in increased activity of AHR protein] which results in increased expression of GSTM3 mRNA22496397
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of GSTM3 mRNA18172886|1879615
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of GSTM3 mRNA21215274
D013752TetracyclineTetracycline results in decreased activity of GSTM3 protein11807801
D013752TetracyclineTetracycline results in decreased expression of GSTM3 mRNA17522070
D013755Tetradecanoylphorbol Acetate[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of GSTM3 mRNA25613284
D013806TheophyllineTheophylline results in decreased expression of GSTM3 mRNA17522070
D013853Thioacetamide[Diethylnitrosamine co-treated with Thioacetamide] results in decreased expression of GSTM3 mRNA28943392
D013853ThioacetamideThioacetamide results in increased expression of GSTM3 mRNA23411599
C009495titanium dioxidetitanium dioxide results in decreased expression of GSTM3 mRNA23557971
D014050TolueneToluene affects the expression of GSTM3 mRNA18653662
D014212TretinoinTretinoin results in increased expression of GSTM3 mRNA21934132
C032910triadimefonNR1H3 gene mutant form promotes the reaction [triadimefon results in increased expression of GSTM3 mRNA]25949234
C032910triadimefontriadimefon results in increased expression of GSTM3 mRNA23970803|2594923
C032910triadimefontriadimefon results in increased expression of GSTM3 mRNA16643972
D014241TrichloroethyleneTrichloroethylene results in increased expression of GSTM3 mRNA25549359
C012589trichostatin Atrichostatin A inhibits the reaction [Nickel affects the expression of GSTM3 mRNA]14575637
C012589trichostatin Atrichostatin A results in increased expression of GSTM3 mRNA24935251
C010360triethylleadtriethyllead results in decreased expression of GSTM3 mRNA9020200
C015559trimellitic anhydridetrimellitic anhydride results in decreased expression of GSTM3 mRNA19042947
C016805tris(1,3-dichloro-2-propyl)phosphate"tris(1,3-dichloro-2-propyl)phosphate results in decreased expression of GSTM3 mRNA"26179874
D014315TriterpenesTriterpenes results in increased expression of GSTM3 mRNA18544911
C057693troglitazonetroglitazone results in decreased expression of GSTM3 mRNA19631733
C057693troglitazonetroglitazone results in increased expression of GSTM3 mRNA19631733
D014415TunicamycinTunicamycin results in decreased expression of GSTM3 mRNA17127020
C112106UAB 30UAB 30 analog results in decreased expression of GSTM3 mRNA23292798
C112106UAB 30UAB 30 results in increased expression of GSTM3 mRNA23292798
D014580Ursodeoxycholic AcidUrsodeoxycholic Acid results in decreased expression of GSTM3 mRNA15885361
D014635Valproic Acid"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of GSTM3 mRNA"27188386
D014635Valproic AcidValproic Acid results in increased expression of GSTM3 mRNA23179753|2438349
D001335Vehicle EmissionsVehicle Emissions results in increased methylation of GSTM3 gene25560391
D014800VitalliumVitallium analog results in increased expression of GSTM3 mRNA23825117
D009536NiacinamideGliclazide inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of GSTM3 mRNA]21439372
D009536Niacinamideresveratrol inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of GSTM3 mRNA]21439372
D009536Niacinamide[Streptozocin co-treated with Niacinamide] results in decreased expression of GSTM3 mRNA21439372
D015029ZeranolZeranol results in increased expression of GSTM3 mRNA11331657

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0004364glutathione transferase activity-IDA8373352  9545290  10587441  
GO:0004364glutathione transferase activity-TAS-  
GO:0005515protein binding-IPI23355646  
GO:0019899enzyme binding-IPI8373352  
GO:0042802identical protein binding-IPI16189514  19060904  21516116  
GO:0042803protein homodimerization activity-IDA9545290  
GO:0042803protein homodimerization activity-IPI8373352  
GO:0043295glutathione binding-IDA8373352  
GO ID GO Term Qualifier Evidence PubMed
GO:0006749glutathione metabolic process-IDA8373352  10587441  
GO:0008065establishment of blood-nerve barrier-TAS2345169  
GO:0018916nitrobenzene metabolic process-IDA8373352  
GO:0042178xenobiotic catabolic process-IDA8373352  
GO:0043627response to estrogen-IEP10037815  
GO:0070458cellular detoxification of nitrogen compound-IDA8373352  
GO:1901687glutathione derivative biosynthetic process-TAS-  
GO ID GO Term Qualifier Evidence PubMed
GO:0005634nucleus-HDA21630459  
GO:0005737cytoplasm-IDA8373352  
GO:0005829cytosol-IDA-  
GO:0005829cytosol-TAS-  
GO:0035686sperm fibrous sheath-IEA-  
GO:0045171intercellular bridge-IDA-  
GO:0070062extracellular exosome-HDA23533145  
KEGG ID KEGG Term
hsa00480Glutathione metabolism
hsa00980Metabolism of xenobiotics by cytochrome P450
hsa00982Drug metabolism - cytochrome P450
Reactome ID Reactome Term Evidence
R-HSA-1430728MetabolismTAS
R-HSA-156580Phase II - Conjugation of compoundsTAS
R-HSA-156590Glutathione conjugationTAS
R-HSA-211859Biological oxidationsTAS

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
7614465Pulmonary expression of glutathione S-transferase M3 in lung cancer patients: association with GSTM1 polymorphism, smoking, and asbestos exposure. (1995 Aug 1)Anttila SCancer Res
17565746Prospective study of urinary excretion of 7-methylguanine and the risk of lung cancer: Effect modification by mu class glutathione-S-transferases. (2007 Oct 1)Loft SInt J Cancer
20847076Genetic susceptibility to asbestos-related fibrotic pleuropulmonary changes. (2011 Sep)Kukkonen MKEur Respir J
18668224Association of GSTM3 intron 6 variant with cigarette smoking, tobacco chewing and alcohol as modifier factors for prostate cancer risk. (2009 Apr)Kesarwani PArch Toxicol
9592753[Effect of gene polymorphism on detoxifying glutathione-S-transferase enzymes on chromosomal stability of squamous epithelial carcinomas in the area of the head-neck]. (1998 Apr)Matthias CLaryngorhinootologie
22027651Genetic polymorphisms of xenobiotic-metabolizing enzymes influence the risk of pulmonary emphysema. (2011 Dec)Kukkonen MKPharmacogenet Genomics
15654505Association of habitual smoking and drinking with single nucleotide polymorphism (SNP) in 40 candidate genes: data from random population-based Japanese samples. (2005)Liu YJ Hum Genet
16886896Glutathione S-transferases mu 1, theta 1, pi 1, alpha 1 and mu 3 genetic polymorphisms and the risk of colorectal and gastric cancers in humans. (2006 Jul)Martinez CPharmacogenomics
15829318Polymorphisms in genes involved in xenobiotic metabolism and lung cancer risk under the age of 60 years. A pooled study of lung cancer patients in Denmark and Norway. (2005 May)Skuladottir HLung Cancer
10077151Glutathione S-transferase GSTM1, GSTM3, GSTP1 and GSTT1 genotypes and the risk of smoking-related oral and pharyngeal cancers. (1999 Mar 31)Jourenkova-Mironova NInt J Cancer
18569590The influence of polymorphisms of glutathione S-transferases M1 and M3 on the development of human urothelial cancer. (2008)Golka KJ Toxicol Environ Health A
10080124[Genetic predisposition for the development of head and neck carcinomas]. (1999 Jan)Jahnke VLaryngorhinootologie
25040976Susceptibility of lung cancer with polymorphisms of CYP1A1, GSTM1, GSTM3, GSTT1 and GSTP1 genotypes in the population of Inner Mongolia region. (2014)Jiang XYAsian Pac J Cancer Prev
25892883Polymorphisms of glutathione S-transferase genes and survival of resected hepatocellular carcinoma patients. (2015 Apr 14)Qu KWorld J Gastroenterol
10022746Polymorphism in cytochrome P450 CYP2D6, CYP1A1, CYP2E1 and glutathione S-transferase, GSTM1, GSTM3, GSTT1 and susceptibility to tobacco-related cancers: studies in upper aerodigestive tract cancers. (1998 Apr)Matthias CPharmacogenetics
8988674Glutathione S-transferase and cytochrome-P-450 polymorphism as risk factors for squamous cell carcinoma of the larynx. (1996 Dec)Jahnke VAm J Surg
14735473Glutathione S-transferase M3 (A/A) genotype as a risk factor for oral cancer and leukoplakia among Indian tobacco smokers. (2004 Mar)Sikdar NInt J Cancer
11408349Glutathione-S-transferase gene polymorphisms in colorectal cancer patients: interaction between GSTM1 and GSTM3 allele variants as a risk-modulating factor. (2001 Jul)Loktionov ACarcinogenesis
10493261The glutathione S-transferases: influence of polymorphism on cancer susceptibility. (1999)Strange RCIARC Sci Publ
21513434Association of genetic polymorphism of GSTT1, GSTM1 and GSTM3 in COPD patients in a north Indian population. (2011 Jun)Shukla RKCOPD
10676631High-activity microsomal epoxide hydrolase genotypes and the risk of oral, pharynx, and larynx cancers. (2000 Feb 1)Jourenkova-Mironova NCancer Res
18258609A comprehensive analysis of phase I and phase II metabolism gene polymorphisms and risk of non-small cell lung cancer in smokers. (2008 Jun)Zienolddiny SCarcinogenesis
19407363GSTM1, GSTM3 and GSTT1 gene variants and risk of benign prostate hyperplasia in North India. (2009)Mittal RDDis Markers
9918133Role of glutathione S-transferase GSTM1, GSTM3, GSTP1 and GSTT1 genotypes in modulating susceptibility to smoking-related lung cancer. (1998 Dec)Jourenkova-Mironova NPharmacogenetics
11040079Polymorphic glutathione S-transferase M1 is a risk factor of primary open-angle glaucoma among Estonians. (2000 Nov)Juronen EExp Eye Res
17372252An international case-control study of glutathione transferase and functionally related polymorphisms and risk of primary adult brain tumors. (2007 Mar)Schwartzbaum JACancer Epidemiol Biomarkers Prev
7728947Expression and polymorphism of glutathione S-transferase in human lungs: risk factors in smoking-related lung cancer. (1995 Apr)Nakajima TCarcinogenesis
10407823[Immunohistologic and molecular genetic studies of the effect of glutathione-S-transferases on the development of squamous epithelial carcinomas in the area of the head-neck]. (1999 Apr)Matthias CLaryngorhinootologie
22108414Human GSTs polymorphisms in the Hakka population of south China and their associations with family history of several chronic diseases. (2011 Oct)Pan SBiomed Environ Sci
9077484Truncal tumor site is associated with high risk of multiple basal cell carcinoma and is influenced by glutathione S-transferase, GSTT1, and cytochrome P450, CYP1A1 genotypes, and their interaction. (1997 Apr)Lear JTJ Invest Dermatol
11548073Significance of genetic polymorphisms in glutathione S-transferase multigene family and lung cancer risk. (2001)Reszka EInt J Occup Med Environ Health
12359356Microsomal epoxide hydrolase and glutathione S-transferase polymorphisms in relation to laryngeal carcinoma risk. (2002 Dec 10)To-Figueras JCancer Lett
20661821Association of xenobiotic metabolizing enzymes genetic polymorphisms with esophageal cancer in Kashmir Valley and influence of environmental factors. (2010)Malik MANutr Cancer
16112301NAT2 slow acetylation, GSTM1 null genotype, and risk of bladder cancer: results from the Spanish Bladder Cancer Study and meta-analyses. (2005 Aug 20-26)Garcia-Closas MLancet
9679751Combined effect of polymorphic GST genes on individual susceptibility to lung cancer. (1998 Aug 12)Saarikoski STInt J Cancer
24177223Significant interactions between maternal PAH exposure and haplotypes in candidate genes on B[a]P-DNA adducts in a NYC cohort of non-smoking African-American and Dominican mothers and newborns. (2014 Jan)Iyer SCarcinogenesis