Gene: RBM15B

29890
HUMAGCGB|OTT3
RNA binding motif protein 15B
protein-coding
3p21.2
Ensembl:ENSG00000259956 MIM:612602 Vega:OTTHUMG00000156896 UniprotKB:Q8NDT2
NC_000003.12
SNP Mapped
1   ANCO-SNPs
AD
0   
NA (AD)  NA (ND)   (Frontal_Cortex)
3.458e-1 (AD)  6.822e-1 (ND)

ANCO-SNPs

SNP ID Position Alleles Trait Variation Type
rs3804766chr3:51393226 (GRCh38.p7)A>Calcohol dependenceSNV(Single Nucleotide Variation)

DNA Methylation

There is no related methylation information for this gene.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
OTUD50.946
TESK10.944
DNAJC50.942
GSK3A0.942
CRMP10.941
VPS26B0.941
PSMD30.94
DHX300.939
UBE2I0.938
RIC8A0.937

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
OR4F5-0.7
OR4F29-0.641
CTNNA3-0.382
TFPI2-0.369
RAI14-0.365
MTRNR2L6-0.354
SGMS2-0.349
SH2D1A-0.346
MTRNR2L9-0.343
CST7-0.331

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C0067181,12-benzoperylene"1,12-benzoperylene results in decreased expression of RBM15B mRNA"26377693
C0284741,4-bis(2-(3,5-dichloropyridyloxy))benzene"1,4-bis(2-(3,5-dichloropyridyloxy))benzene results in increased expression of RBM15B mRNA"22698814
D000082AcetaminophenAcetaminophen affects the expression of RBM15B mRNA17562736
C030935benz(a)anthracenebenz(a)anthracene results in decreased expression of RBM15B mRNA26377693
C018475butyraldehydebutyraldehyde results in decreased expression of RBM15B mRNA26079696
C018021cobaltous chloridecobaltous chloride results in decreased expression of RBM15B mRNA19320972
D003300Copper[NSC 689534 binds to Copper] which results in decreased expression of RBM15B mRNA20971185
D016572CyclosporineCyclosporine results in decreased expression of RBM15B mRNA25562108
C014347decitabinedecitabine affects the expression of RBM15B mRNA23300844
D003976DiazinonDiazinon results in increased methylation of RBM15B gene22964155
D002945CisplatinCisplatin affects the expression of RBM15B mRNA23300844
D004041Dietary FatsDietary Fats results in decreased expression of RBM15B mRNA25016146
C045651epigallocatechin gallate[potassium chromate(VI) co-treated with epigallocatechin gallate] results in increased expression of RBM15B mRNA22079256
D005839GentamicinsGentamicins results in decreased expression of RBM15B mRNA22061828
D015759Ionomycin[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of RBM15B mRNA25613284
D008741Methyl MethanesulfonateMethyl Methanesulfonate results in decreased expression of RBM15B mRNA23649840
C558013NSC 689534[NSC 689534 binds to Copper] which results in decreased expression of RBM15B mRNA20971185
D010416PentachlorophenolPentachlorophenol results in increased expression of RBM15B mRNA23892564
C046012pentanalpentanal results in decreased expression of RBM15B mRNA26079696
C027373potassium chromate(VI)[potassium chromate(VI) co-treated with epigallocatechin gallate] results in increased expression of RBM15B mRNA22079256
C027373potassium chromate(VI)potassium chromate(VI) results in increased expression of RBM15B mRNA22079256
C012526quercitrinquercitrin results in increased expression of RBM15B mRNA25193878
C513635S-2-pentyl-4-pentynoic hydroxamic acidS-2-pentyl-4-pentynoic hydroxamic acid results in decreased expression of RBM15B mRNA21427059
C017947sodium arsenitesodium arsenite results in increased expression of RBM15B mRNA17879257
D018038Sodium SeleniteSodium Selenite results in increased expression of RBM15B mRNA18175754
D013755Tetradecanoylphorbol Acetate[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of RBM15B mRNA25613284
C016805tris(1,3-dichloro-2-propyl)phosphate"tris(1,3-dichloro-2-propyl)phosphate results in decreased expression of RBM15B mRNA"26179874
D014520UrethaneUrethane results in decreased expression of RBM15B mRNA28818685
D014635Valproic AcidValproic Acid results in decreased expression of RBM15B mRNA29154799
D014635Valproic AcidValproic Acid results in increased methylation of RBM15B gene29154799
D014635Valproic AcidValproic Acid results in decreased expression of RBM15B mRNA21427059

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0003676nucleic acid binding-IBA21873635  
GO:0003723RNA binding-HDA22658674  22681889  
GO:0003723RNA binding-IDA27602518  
GO:0003723RNA binding-NAS16129689  
GO:0005515protein binding-IPI16129689  25416956  
GO ID GO Term Qualifier Evidence PubMed
GO:0000381regulation of alternative mRNA splicing, via spliceosome-IBA21873635  
GO:0000381regulation of alternative mRNA splicing, via spliceosome-IDA16129689  
GO:0000398mRNA splicing, via spliceosome-IBA21873635  
GO:0001510RNA methylation-IDA27602518  
GO:0006351transcription, DNA-templated-IEA-  
GO:0006397mRNA processing-IEA-  
GO:0006406mRNA export from nucleus-ISS-  
GO:0006913nucleocytoplasmic transportNOTIDA16129689  
GO:0008380RNA splicing-IEA-  
GO:0009048dosage compensation by inactivation of X chromosome-IDA27602518  
GO:0016032viral process-IEA-  
GO:0045892negative regulation of transcription, DNA-templatedNOTIDA16129689  
GO ID GO Term Qualifier Evidence PubMed
GO:0005634nucleus-IBA21873635  
GO:0005635nuclear envelope-IDA19586903  
GO:0005654nucleoplasm-IDA16129689  
GO:0005730nucleolusNOTIDA16129689  
GO:0016607nuclear speck-IDA19586903  
GO:0036396RNA N6-methyladenosine methyltransferase complex-IDA27602518  
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal