Gene info: ID 29970

SNP ID	Position	Alleles	Trait	Variation Type
rs2595248	chr3:159300738 (GRCh38.p7)	T>C	nicotine dependence	SNV(Single Nucleotide Variation)

Probe	Locus(GRCh37)	Gene	p-val	Trait	PubMed ID
cg23553912	chr3:159558031	SCHIP1	2.150e-8	Maternal smoking in pregnancy	27040690
cg23553912	chr3:159558031	SCHIP1	3.280e-8	Maternal smoking in pregnancy	27040690
cg23553912	chr3:159558031	SCHIP1	7.000e-8	Maternal smoking in pregnancy	27040690

Gene Symbol	Pearson Correlation Coefficient
AMN1	0.869
IQCJ-SCHIP1	0.859
DNAJC6	0.853
TPPP	0.849
CLCN4	0.843
VKORC1L1	0.838
WDR47	0.837
SRPK2	0.837
MAPK10	0.835
TDRKH	0.833

Gene Symbol	Pearson Correlation Coefficient
CSAG1	-0.498
EBF1	-0.486
MTRNR2L10	-0.48
MTRNR2L6	-0.48
FMO3	-0.477
CST7	-0.45
RNF135	-0.45
SIX1	-0.444
IL18RAP	-0.437
MTRNR2L9	-0.435

DrugBank
CTD

There is no DrugBank record for this gene !

ID	Drug Name	Action	PubMed
C459179	4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide	"[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SCHIP1 mRNA"	27188386
C516138	(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine	"[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SCHIP1 mRNA"	27188386
D000082	Acetaminophen	Acetaminophen results in decreased expression of SCHIP1 mRNA	21420995
D000086	Acetazolamide	Acetazolamide results in increased expression of SCHIP1 mRNA	19274763
C016601	afimoxifene	afimoxifene inhibits the reaction [Estrogens results in decreased expression of SCHIP1 mRNA]	21233418
D016604	Aflatoxin B1	Aflatoxin B1 results in decreased expression of SCHIP1 mRNA	19770486
D000535	Aluminum	[APP protein modified form binds to Aluminum] which results in decreased expression of SCHIP1 mRNA	21298039
D001151	Arsenic	Arsenic affects the methylation of SCHIP1 gene	25304211
D001280	Atrazine	Atrazine results in decreased expression of SCHIP1 mRNA	22378314
D019324	beta-Naphthoflavone	[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of SCHIP1 mRNA	18164116
D001564	Benzo(a)pyrene	Benzo(a)pyrene results in increased expression of SCHIP1 mRNA	20106945
D001564	Benzo(a)pyrene	Benzo(a)pyrene results in increased mutagenesis of SCHIP1 gene	25435355
D001564	Benzo(a)pyrene	Benzo(a)pyrene results in decreased expression of SCHIP1 mRNA	19770486
D001564	Benzo(a)pyrene	Benzo(a)pyrene results in increased expression of SCHIP1 mRNA	22228805
D015123	7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide	"7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of SCHIP1 mRNA"	19150397
C038328	BEP protocol	BEP protocol results in increased expression of SCHIP1 mRNA	18987330
C006780	bisphenol A	bisphenol A results in decreased expression of SCHIP1 mRNA	25047013\|2927551
C006780	bisphenol A	bisphenol A results in decreased expression of SCHIP1 mRNA	25181051
C006780	bisphenol A	bisphenol A results in increased methylation of SCHIP1 gene	28505145
D000069286	Bortezomib	Bortezomib results in decreased expression of SCHIP1 mRNA	20977926
D002251	Carbon Tetrachloride	Carbon Tetrachloride affects the expression of SCHIP1 mRNA	17484886
D002794	Choline	[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of SCHIP1 gene	20938992
D019327	Copper Sulfate	Copper Sulfate results in increased expression of SCHIP1 mRNA	19549813
D003471	Cuprizone	Cuprizone results in decreased expression of SCHIP1 mRNA	26577399
D016572	Cyclosporine	Cyclosporine results in decreased expression of SCHIP1 mRNA	20106945
D016572	Cyclosporine	Cyclosporine results in increased methylation of SCHIP1 promoter	27989131
D003907	Dexamethasone	Dexamethasone inhibits the reaction [RX3 gene mutant form affects the expression of SCHIP1 mRNA]	27941970
D003993	Dibutyl Phthalate	Dibutyl Phthalate results in increased expression of SCHIP1 mRNA	17361019\|2126653
D003993	Dibutyl Phthalate	Dibutyl Phthalate results in increased expression of SCHIP1 mRNA	21266533
D002945	Cisplatin	Cisplatin results in increased expression of SCHIP1 mRNA	27392435
D004041	Dietary Fats	Dietary Fats results in decreased expression of SCHIP1 mRNA	18042831
D004052	Diethylnitrosamine	[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of SCHIP1 mRNA	18164116
C118739	entinostat	entinostat results in decreased expression of SCHIP1 mRNA	27188386
D004967	Estrogens	afimoxifene inhibits the reaction [Estrogens results in decreased expression of SCHIP1 mRNA]	21233418
D004967	Estrogens	Estrogens results in decreased expression of SCHIP1 mRNA	21233418
D005492	Folic Acid	[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of SCHIP1 gene	20938992
C039281	furan	furan results in increased expression of SCHIP1 mRNA	27387713
D019833	Genistein	Genistein results in decreased expression of SCHIP1 mRNA	20884965
D017313	Fenretinide	Fenretinide results in increased expression of SCHIP1 mRNA	28973697
C544151	jinfukang	jinfukang results in decreased expression of SCHIP1 mRNA	27392435
C561695	(+)-JQ1 compound	(+)-JQ1 compound results in decreased expression of SCHIP1 mRNA	25307878
D007657	Ketone Bodies	Ketone Bodies results in increased expression of SCHIP1 mRNA	16807920
C008261	lead acetate	lead acetate results in increased expression of SCHIP1 mRNA	21829687
D008715	Methionine	[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of SCHIP1 gene	20938992
D008942	Mitoxantrone	SCHIP1 protein affects the susceptibility to Mitoxantrone	16217747
D000073878	Palm Oil	Palm Oil results in decreased expression of SCHIP1 mRNA	18042831
C568608	PCI 5002	[PCI 5002 co-treated with Zinc] results in increased expression of SCHIP1 mRNA	18593933
C006253	pirinixic acid	[pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of SCHIP1 mRNA	19710929
D012822	Silicon Dioxide	Silicon Dioxide results in increased expression of SCHIP1 mRNA	23221170
D012834	Silver	Silver results in increased expression of SCHIP1 mRNA	28959546
C009277	sodium arsenate	sodium arsenate results in increased expression of SCHIP1 mRNA	21795629
C501413	tesaglitazar	tesaglitazar results in increased expression of SCHIP1 mRNA	21515302
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin affects the expression of SCHIP1 mRNA	21570461
D014212	Tretinoin	Tretinoin results in increased expression of SCHIP1 mRNA	23724009
C012589	trichostatin A	"[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SCHIP1 mRNA"	27188386
D014635	Valproic Acid	Valproic Acid affects the expression of SCHIP1 mRNA	25979313
D014635	Valproic Acid	Valproic Acid results in decreased methylation of SCHIP1 gene	29154799
D014635	Valproic Acid	Valproic Acid affects the expression of SCHIP1 mRNA	17963808
D001335	Vehicle Emissions	Vehicle Emissions affects the methylation of SCHIP1 gene	25560391
D015032	Zinc	[PCI 5002 co-treated with Zinc] results in increased expression of SCHIP1 mRNA	18593933

GO ID	GO Term	Qualifier	Evidence	PubMed
GO:0005515	protein binding	-	IPI	20195357
GO:0042802	identical protein binding	-	IPI	10669747 20195357

Gene: SCHIP1

ANCO-SNPs

DNA Methylation

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Top 10 negatively co-expressed genes

Drugs/Compounds

There is no DrugBank record for this gene !

GO/Pathway

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)