Gene info: ID 301

Gene: ANXA1

GENE ID: 301

Synonyms: ANX1|LPC1

Description: annexin A1

Gene type: protein-coding

Location: 9q21.13

dbXrefs: Ensembl:ENSG00000135046 MIM:151690 Vega:OTTHUMG00000020016 UniprotKB:P04083

RefSeq: NC_000009.12

Retrived from: PubMed

SNPs: 0 ANCO-SNPs

Phenotype: ND

# Publications: 2

Sherlock p-value : NA (AD) NA (ND) (Frontal_Cortex)

Pascal p-value : 6.463e-1 (AD) 2.998e-1 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol	Pearson Correlation Coefficient
ANXA2	0.83
S100A10	0.81
CLIC1	0.797
IL1R1	0.793
TAGLN2	0.787
TM4SF1	0.784
CASP4	0.782
IFI16	0.781
GBP2	0.777
ANO6	0.775

Top 10 negatively co-expressed genes

Gene Symbol	Pearson Correlation Coefficient
MARCH4	-0.473
KIT	-0.443
KCNQ4	-0.437
DLGAP3	-0.434
FBLN7	-0.432
PAK6	-0.426
TPBGL	-0.424
WNT7A	-0.417
DLK2	-0.417
CDH22	-0.415

ID	Drug Name	Drug Type	CAS Num	Status	Role
DB00288	Amcinonide	Small Molecule	51022-69-6	Approved	Target
DB00741	Hydrocortisone	Small Molecule	50-23-7	Approved	Target
DB01234	Dexamethasone	Small Molecule	50-02-2	Approved\|Investigational	Target

ID	Drug Name	Action	PubMed
C052383	1,1-bis(4-hydroxyphenyl)-2-phenylbut-1-ene	"1,1-bis(4-hydroxyphenyl)-2-phenylbut-1-ene results in increased expression of ANXA1 mRNA"	23373633
C049325	1,2-dithiol-3-thione	"1,2-dithiol-3-thione results in decreased expression of ANXA1 mRNA"	19162173
C020175	16 alpha-ethyl-21-hydroxy-19-nor-4-pregnene-3,20-dione	"16 alpha-ethyl-21-hydroxy-19-nor-4-pregnene-3,20-dione results in increased expression of ANXA1 mRNA"	20519331
C111118	2',3,3',4',5-pentachloro-4-hydroxybiphenyl	"2',3,3',4',5-pentachloro-4-hydroxybiphenyl results in decreased expression of ANXA1 mRNA"	19114083
C023514	2,6-dinitrotoluene	"2,6-dinitrotoluene results in increased expression of ANXA1 mRNA"	20406850
C049584	2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine	"2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of ANXA1 mRNA"	12376462
C006593	2-anthramine	2-anthramine results in increased expression of ANXA1 mRNA	23038007
C030370	2-methoxy-5-(2',3',4'-trimethoxyphenyl)tropone	"2-methoxy-5-(2',3',4'-trimethoxyphenyl)tropone results in increased expression of ANXA1 mRNA"	20206263
C026137	3-hydroxyacetanilide	3-hydroxyacetanilide results in decreased expression of ANXA1 mRNA	18544908
C009505	4,4'-diaminodiphenylmethane	"4,4'-diaminodiphenylmethane results in increased expression of ANXA1 mRNA"	25380136
C459179	4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide	"[NOG protein co-treated with mercuric bromide co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ANXA1 mRNA"	27188386
C459179	4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide	"[NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ANXA1 mRNA"	27188386
C459179	4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide	"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ANXA1 mRNA"	27188386
C459179	4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide	"[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ANXA1 mRNA"	27188386
C108123	4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine	"4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [Dexamethasone results in increased phosphorylation of ANXA1 protein]"	10807665
C002202	4-oxoretinoic acid	4-oxoretinoic acid results in increased expression of ANXA1 mRNA	15982314
C029728	4-phenylenediamine	4-phenylenediamine results in increased expression of ANXA1 mRNA	16314067
C516138	(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine	"[NOG protein co-treated with mercuric bromide co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ANXA1 mRNA"	27188386
C516138	(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine	"[NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ANXA1 mRNA"	27188386
C516138	(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine	"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ANXA1 mRNA"	27188386
C516138	(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine	"[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ANXA1 mRNA"	27188386
C553817	7-(benzylamino)-1,3,4,8-tetrahydropyrrolo(4,3,2-de)quinolin-8(1H)-one	"7-(benzylamino)-1,3,4,8-tetrahydropyrrolo(4,3,2-de)quinolin-8(1H)-one results in increased expression of ANXA1 mRNA"	19936915
D000082	Acetaminophen	Acetaminophen results in increased expression of ANXA1 mRNA	29067470
D000082	Acetaminophen	Acetaminophen affects the expression of ANXA1 mRNA	17562736
D000082	Acetaminophen	Acetaminophen results in increased expression of ANXA1 mRNA	18544908
D000255	Adenosine Triphosphate	arsenite affects the reaction [[Magnesium co-treated with Adenosine Triphosphate] affects the activity of ANXA1 protein]	20655937
D000255	Adenosine Triphosphate	Cadmium affects the reaction [[Magnesium co-treated with Adenosine Triphosphate] affects the activity of ANXA1 protein]	20655937
D000255	Adenosine Triphosphate	chromium hexavalent ion affects the reaction [[Magnesium co-treated with Adenosine Triphosphate] affects the activity of ANXA1 protein]	20655937
D000255	Adenosine Triphosphate	Lead affects the reaction [[Magnesium co-treated with Adenosine Triphosphate] affects the activity of ANXA1 protein]	20655937
D000255	Adenosine Triphosphate	[Magnesium co-treated with Adenosine Triphosphate] affects the activity of ANXA1 protein	20655937
D016604	Aflatoxin B1	Aflatoxin B1 affects the expression of ANXA1 protein	20106945
D016604	Aflatoxin B1	Aflatoxin B1 results in increased expression of ANXA1 mRNA	22100608\|2715375
D016604	Aflatoxin B1	Aflatoxin B1 results in decreased expression of ANXA1 mRNA	19770486
C103303	alitretinoin	alitretinoin results in decreased expression of ANXA1 protein	28886987
D000517	alpha-Chlorohydrin	alpha-Chlorohydrin results in increased expression of ANXA1 protein	26072098
D000643	Ammonium Chloride	Ammonium Chloride affects the expression of ANXA1 mRNA	16483693
C023650	aniline	aniline results in increased nitrosation of ANXA1 protein	21708182
D001151	Arsenic	Arsenic results in decreased expression of ANXA1 protein	19818359
C006632	arsenic trioxide	ANXA1 mutant form results in increased susceptibility to arsenic trioxide	25983101
C006632	arsenic trioxide	arsenic trioxide results in decreased expression of ANXA1 protein	25258189
C006632	arsenic trioxide	arsenic trioxide results in increased expression of and results in increased secretion of ANXA1 protein	18081892
C006632	arsenic trioxide	arsenic trioxide results in increased expression of ANXA1 mRNA	22521957\|2598310
C006632	arsenic trioxide	arsenic trioxide results in increased expression of ANXA1 protein	25983101
C015001	arsenite	arsenite affects the activity of ANXA1 protein	20655937
C015001	arsenite	arsenite affects the reaction [[Magnesium co-treated with Adenosine Triphosphate] affects the activity of ANXA1 protein]	20655937
D001205	Ascorbic Acid	[Quercetin co-treated with Ascorbic Acid] results in increased expression of ANXA1 mRNA	17639512
D001205	Ascorbic Acid	Ascorbic Acid results in increased expression of ANXA1 mRNA	15372504
D001280	Atrazine	Atrazine affects the expression of ANXA1 mRNA	25929836
D001374	Azacitidine	Azacitidine results in decreased expression of ANXA1 protein	17105402
D019324	beta-Naphthoflavone	[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of ANXA1 mRNA	18164116
D001564	Benzo(a)pyrene	Benzo(a)pyrene results in decreased expression of ANXA1 mRNA	19770486
D001564	Benzo(a)pyrene	Benzo(a)pyrene results in increased expression of ANXA1 mRNA	22228805
D015123	7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide	"7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased expression of ANXA1 mRNA"	19150397\|2001819
D004958	Estradiol	Estradiol results in increased expression of ANXA1 mRNA	23373633
D004958	Estradiol	Estradiol results in increased expression of ANXA1 mRNA	19484750
D001663	Bilirubin	Bilirubin results in decreased expression of ANXA1 mRNA	20196124
C006780	bisphenol A	bisphenol A affects the expression of ANXA1 mRNA	25181051
C423844	BL 11282	BL 11282 results in increased expression of ANXA1 protein	17458497
C584509	C646 compound	C646 compound results in decreased expression of ANXA1 mRNA	26191083
D002104	Cadmium	Cadmium results in decreased expression of ANXA1 mRNA	16439709
D002104	Cadmium	Cadmium results in increased expression of ANXA1 mRNA	21120746
D002104	Cadmium	Cadmium affects the activity of ANXA1 protein	20655937
D002104	Cadmium	Cadmium affects the reaction [[Magnesium co-treated with Adenosine Triphosphate] affects the activity of ANXA1 protein]	20655937
D019256	Cadmium Chloride	Cadmium Chloride results in decreased expression of ANXA1 protein	24419708
D019256	Cadmium Chloride	Cadmium Chloride results in increased expression of ANXA1 protein	24527689
D019256	Cadmium Chloride	Cadmium Chloride affects the expression of ANXA1 mRNA	18804290
C037123	cadmium sulfate	cadmium sulfate results in increased expression of ANXA1 mRNA	12064557\|1467641
D002118	Calcium	Calcium affects the activity of ANXA1 protein	20655937
D002220	Carbamazepine	Carbamazepine affects the expression of ANXA1 mRNA	25979313
C010063	carbonyl sulfide	carbonyl sulfide results in increased expression of ANXA1 mRNA	19395590
D002273	Carcinogens	Carcinogens results in increased expression of ANXA1 mRNA	16316942
D002351	Carrageenan	ANXA1 protein affects the susceptibility to Carrageenan	12475898
D002351	Carrageenan	ANXA1 protein affects the susceptibility to [Dexamethasone co-treated with Carrageenan]	12475898
D020111	Chlorodiphenyl (54% Chlorine)	Chlorodiphenyl (54% Chlorine) results in decreased expression of ANXA1 mRNA	23650126
D020245	p-Chloromercuribenzoic Acid	"[NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ANXA1 mRNA"	27188386
D020245	p-Chloromercuribenzoic Acid	p-Chloromercuribenzoic Acid results in increased expression of ANXA1 mRNA	26272509
C100187	chloropicrin	chloropicrin results in increased expression of ANXA1 mRNA	26352163
D002794	Choline	[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of ANXA1 mRNA	20938992
C074702	chromium hexavalent ion	chromium hexavalent ion affects the activity of ANXA1 protein	20655937
C074702	chromium hexavalent ion	chromium hexavalent ion affects the reaction [[Magnesium co-treated with Adenosine Triphosphate] affects the activity of ANXA1 protein]	20655937
D003300	Copper	ANXA1 protein binds to Copper	14534351
D019327	Copper Sulfate	Copper Sulfate results in increased expression of ANXA1 mRNA	19549813
C423222	cotylenin A	cotylenin A results in increased expression of ANXA1 mRNA	16129123
D003471	Cuprizone	Cuprizone results in increased expression of ANXA1 mRNA	26577399
D016572	Cyclosporine	Cyclosporine results in increased expression of ANXA1 mRNA	20106945\|2798913
D016572	Cyclosporine	Cyclosporine results in decreased expression of ANXA1 mRNA	19770486
C014347	decitabine	decitabine affects the expression of ANXA1 mRNA	23300844
D003703	Demecolcine	Demecolcine results in increased expression of ANXA1 mRNA	23649840
D064791	Desoxycorticosterone Acetate	"[Desoxycorticosterone Acetate co-treated with Sodium Chloride, Dietary co-treated with Potassium Chloride] results in increased expression of ANXA1 mRNA"	22228705
D003907	Dexamethasone	"4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [Dexamethasone results in increased phosphorylation of ANXA1 protein]"	10807665
D003907	Dexamethasone	ANXA1 protein inhibits the reaction [Dexamethasone results in decreased susceptibility to CXCL8 protein]	7522859
D003907	Dexamethasone	Dexamethasone promotes the reaction [EGFR protein binds to ANXA1 protein modified form]	10807665
D003907	Dexamethasone	Dexamethasone results in increased expression of ANXA1 protein	10807665
D003907	Dexamethasone	Dexamethasone results in increased localization of ANXA1 protein modified form	10807665
D003907	Dexamethasone	Dexamethasone results in increased phosphorylation of ANXA1 protein	10807665
D003907	Dexamethasone	Mifepristone inhibits the reaction [Dexamethasone promotes the reaction [EGFR protein binds to ANXA1 protein modified form]]	10807665
D003907	Dexamethasone	Mifepristone inhibits the reaction [Dexamethasone results in increased localization of ANXA1 protein modified form]	10807665
D003907	Dexamethasone	Mifepristone inhibits the reaction [Dexamethasone results in increased phosphorylation of and results in increased expression of ANXA1 protein]	10807665
D003907	Dexamethasone	ANXA1 protein affects the susceptibility to Dexamethasone	12475898
D003907	Dexamethasone	ANXA1 protein affects the susceptibility to [Dexamethasone co-treated with Carrageenan]	12475898
D003907	Dexamethasone	ANXA1 protein affects the susceptibility to Dexamethasone	15472012
C042577	diallyl trisulfide	diallyl trisulfide results in increased expression of ANXA1 mRNA	16344271
C042577	diallyl trisulfide	diallyl trisulfide results in increased expression of ANXA1 protein	16344271
D003976	Diazinon	Diazinon affects the expression of ANXA1 mRNA	22546817
D003993	Dibutyl Phthalate	Dibutyl Phthalate results in increased expression of ANXA1 mRNA	17361019\|2126653
D003993	Dibutyl Phthalate	Dibutyl Phthalate results in increased expression of ANXA1 mRNA	21266533
D002945	Cisplatin	ANXA1 protein affects the susceptibility to Cisplatin	16217747
D002945	Cisplatin	Cisplatin affects the expression of ANXA1 mRNA	23300844
D002945	Cisplatin	Cisplatin results in increased expression of ANXA1 mRNA	27594783
D002945	Cisplatin	Cisplatin results in increased expression of ANXA1 protein	21924258
D002945	Cisplatin	Cisplatin results in increased expression of ANXA1 mRNA	21151649
D004026	Dieldrin	Dieldrin affects the expression of ANXA1 mRNA	22546817
D004041	Dietary Fats	Dietary Fats results in increased expression of ANXA1 mRNA	19030233
D004041	Dietary Fats	rimonabant inhibits the reaction [Dietary Fats results in increased expression of ANXA1 mRNA]	19030233
D004051	Diethylhexyl Phthalate	[Diethylhexyl Phthalate co-treated with Genistein] results in decreased expression of ANXA1 mRNA	25031359
D004052	Diethylnitrosamine	[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of ANXA1 mRNA	18164116
D004052	Diethylnitrosamine	[Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of ANXA1 protein	20935162
D004052	Diethylnitrosamine	[Diethylnitrosamine co-treated with Thioacetamide] results in increased expression of ANXA1 mRNA	28943392
D004052	Diethylnitrosamine	Diethylnitrosamine results in increased expression of ANXA1 mRNA	19638242
D004052	Diethylnitrosamine	Diethylnitrosamine results in increased expression of ANXA1 protein	20935162
D015127	9,10-Dimethyl-1,2-benzanthracene	"[9,10-Dimethyl-1,2-benzanthracene co-treated with Isoflavones] results in increased expression of ANXA1 protein"	22248470
D015127	9,10-Dimethyl-1,2-benzanthracene	"9,10-Dimethyl-1,2-benzanthracene results in increased expression of ANXA1 mRNA"	12376462
D015127	9,10-Dimethyl-1,2-benzanthracene	"9,10-Dimethyl-1,2-benzanthracene results in increased expression of ANXA1 protein"	22248470
D004128	Dimethylnitrosamine	Dimethylnitrosamine results in increased expression of ANXA1 mRNA	25380136
D004137	Dinitrochlorobenzene	Dinitrochlorobenzene results in increased expression of ANXA1 mRNA	16314067
D004050	Ditiocarb	Ditiocarb results in increased expression of ANXA1 mRNA	16603213
D004237	Diuron	Diuron results in decreased expression of ANXA1 mRNA	21551480\|2515243
D004317	Doxorubicin	Doxorubicin affects the expression of ANXA1 protein	29385562
C013525	ENNG	[ENNG co-treated with Isoflavones] results in increased expression of ANXA1 protein	22248470
C013525	ENNG	ENNG results in increased expression of ANXA1 protein	22248470
C118739	entinostat	entinostat results in decreased expression of ANXA1 mRNA	26272509
D000431	Ethanol	Ethanol results in decreased expression of ANXA1 mRNA	15513904
D000431	Ethanol	Ethanol results in decreased expression of ANXA1 mRNA	16946407
D004997	Ethinyl Estradiol	Ethinyl Estradiol results in increased expression of ANXA1 mRNA	17942748
D004997	Ethinyl Estradiol	Ethinyl Estradiol results in increased expression of ANXA1 mRNA	17557909
C024565	ethylene dichloride	ethylene dichloride results in decreased expression of ANXA1 mRNA	28189721
D005020	Ethyl Methanesulfonate	Ethyl Methanesulfonate results in decreased expression of ANXA1 mRNA	23649840
C506425	eurycomanone	eurycomanone results in decreased expression of ANXA1 mRNA	21903368
C506425	eurycomanone	eurycomanone results in decreased expression of ANXA1 protein	21903368
D005472	Fluorouracil	ANXA1 protein affects the susceptibility to Fluorouracil	15352031\|1621774
D005472	Fluorouracil	Fluorouracil results in decreased expression of ANXA1 protein	15352031
D005473	Fluoxetine	Fluoxetine results in decreased expression of ANXA1 mRNA	21852994
D005480	Flurbiprofen	Flurbiprofen results in increased expression of ANXA1 mRNA	16949054
D000068298	Fluticasone	Fluticasone affects the localization of ANXA1 protein	15753895
D005492	Folic Acid	[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of ANXA1 mRNA	20938992
D005557	Formaldehyde	Formaldehyde results in increased expression of ANXA1 mRNA	23649840\|2766457
C039281	furan	furan results in increased expression of ANXA1 mRNA	27387713
D019833	Genistein	ESR2 promotes the reaction [Genistein results in decreased expression of ANXA1 protein]	20884965
D019833	Genistein	Genistein results in decreased expression of ANXA1 protein	20884965
D019833	Genistein	[Diethylhexyl Phthalate co-treated with Genistein] results in decreased expression of ANXA1 mRNA	25031359
D019833	Genistein	[Genistein co-treated with Methoxychlor] results in decreased expression of ANXA1 mRNA	21782745
D019833	Genistein	Genistein results in decreased expression of ANXA1 protein	22649256
D005839	Gentamicins	Gentamicins results in increased expression of ANXA1 mRNA	22061828
D005839	Gentamicins	Gentamicins results in increased expression of ANXA1 protein	22061828
C071834	glycidamide	glycidamide results in decreased expression of ANXA1 mRNA	17822822
D006108	Graphite	Graphite results in increased expression of ANXA1 protein	22157353
D006581	Hexachlorobenzene	Hexachlorobenzene results in increased expression of ANXA1 mRNA	15159207
D017313	Fenretinide	Fenretinide results in decreased expression of ANXA1 mRNA	28973697
D006820	Hyaluronic Acid	Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of ANXA1 protein]	23178681
D006820	Hyaluronic Acid	Hyaluronic Acid analog results in decreased expression of ANXA1 protein	23178681
D006854	Hydrocortisone	Hydrocortisone results in increased expression of ANXA1 mRNA	25763180
D006854	Hydrocortisone	Mifepristone inhibits the reaction [Hydrocortisone results in increased expression of ANXA1 mRNA]	25763180
D006861	Hydrogen Peroxide	Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of ANXA1 protein]	23178681
D006861	Hydrogen Peroxide	Hydrogen Peroxide results in decreased expression of ANXA1 protein	23178681
D007052	Ibuprofen	Ibuprofen affects the expression of ANXA1 mRNA	17070997
C492448	ICG 001	ICG 001 results in decreased expression of ANXA1 mRNA	26191083
D015759	Ionomycin	[Tetradecanoylphorbol Acetate co-treated with Ionomycin] affects the expression of ANXA1 mRNA	25613284
D007501	Iron	Iron deficiency results in decreased expression of ANXA1 mRNA	19821111
D007529	Isoflavones	"[9,10-Dimethyl-1,2-benzanthracene co-treated with Isoflavones] results in increased expression of ANXA1 protein"	22248470
D007529	Isoflavones	[ENNG co-treated with Isoflavones] results in increased expression of ANXA1 protein	22248470
D007545	Isoproterenol	ANXA1 affects the reaction [Isoproterenol results in decreased secretion of IL6 protein]	16835395
D007545	Isoproterenol	Isoproterenol results in increased expression of ANXA1 mRNA	20003209
C561695	(+)-JQ1 compound	(+)-JQ1 compound results in decreased expression of ANXA1 mRNA	23086925
D007654	Ketoconazole	Ketoconazole results in decreased expression of ANXA1 mRNA	25787151
C011890	kojic acid	kojic acid results in decreased expression of ANXA1 mRNA	16595896
C060282	lariciresinol	lariciresinol results in increased expression of ANXA1 protein	27417256
D007854	Lead	Lead affects the activity of ANXA1 protein	20655937
D007854	Lead	Lead affects the reaction [[Magnesium co-treated with Adenosine Triphosphate] affects the activity of ANXA1 protein]	20655937
C008261	lead acetate	lead acetate results in decreased expression of ANXA1 mRNA	11578147
C008261	lead acetate	lead acetate results in decreased expression of ANXA1 protein	11578147
C029891	lead chloride	lead chloride results in increased expression of ANXA1 protein	24419708
D064704	Levofloxacin	Levofloxacin results in decreased expression of ANXA1 mRNA	24136188
D008070	Lipopolysaccharides	ANXA1 protein inhibits the reaction [Lipopolysaccharides results in increased abundance of Dinoprostone]	21777521
D008070	Lipopolysaccharides	ANXA1 protein inhibits the reaction [Lipopolysaccharides results in increased expression of CCL2 mRNA]	21777521
D008070	Lipopolysaccharides	ANXA1 protein inhibits the reaction [Lipopolysaccharides results in increased expression of CXCL2 mRNA]	21777521
D008070	Lipopolysaccharides	ANXA1 protein inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]	21777521
D008070	Lipopolysaccharides	ANXA1 protein inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]	21777521
D008070	Lipopolysaccharides	ANXA1 protein inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]	21777521
D008070	Lipopolysaccharides	ANXA1 protein inhibits the reaction [Lipopolysaccharides results in increased secretion of IL1B protein]	21777521
D008070	Lipopolysaccharides	ANXA1 protein inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]	21777521
D008070	Lipopolysaccharides	ANXA1 protein inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]	21777521
D008070	Lipopolysaccharides	ANXA1 protein affects the reaction [Lipopolysaccharides affects the secretion of IL6 protein]	16633358
D008070	Lipopolysaccharides	ANXA1 protein affects the reaction [Lipopolysaccharides affects the secretion of TNF protein]	16633358
D008070	Lipopolysaccharides	ANXA1 protein inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA]	21777521
D008070	Lipopolysaccharides	ANXA1 protein inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein]	21777521
D008070	Lipopolysaccharides	ANXA1 protein results in decreased susceptibility to Lipopolysaccharides	16835395
D008095	Lithocholic Acid	Lithocholic Acid results in increased expression of ANXA1 mRNA	20359477
D008274	Magnesium	arsenite affects the reaction [[Magnesium co-treated with Adenosine Triphosphate] affects the activity of ANXA1 protein]	20655937
D008274	Magnesium	Cadmium affects the reaction [[Magnesium co-treated with Adenosine Triphosphate] affects the activity of ANXA1 protein]	20655937
D008274	Magnesium	chromium hexavalent ion affects the reaction [[Magnesium co-treated with Adenosine Triphosphate] affects the activity of ANXA1 protein]	20655937
D008274	Magnesium	Lead affects the reaction [[Magnesium co-treated with Adenosine Triphosphate] affects the activity of ANXA1 protein]	20655937
D008274	Magnesium	[Magnesium co-treated with Adenosine Triphosphate] affects the activity of ANXA1 protein	20655937
C042720	mercuric bromide	mercuric bromide results in increased expression of ANXA1 mRNA	26272509
C042720	mercuric bromide	"[NOG protein co-treated with mercuric bromide co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ANXA1 mRNA"	27188386
D008715	Methionine	[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of ANXA1 mRNA	20938992
D008731	Methoxychlor	[Genistein co-treated with Methoxychlor] results in decreased expression of ANXA1 mRNA	21782745
C004925	methylmercuric chloride	methylmercuric chloride results in increased expression of ANXA1 mRNA	23179753\|2627250
D008741	Methyl Methanesulfonate	Methyl Methanesulfonate results in decreased expression of ANXA1 mRNA	23649840
D008825	Miconazole	Miconazole results in decreased expression of ANXA1 mRNA	22262564
D015735	Mifepristone	Mifepristone inhibits the reaction [Dexamethasone promotes the reaction [EGFR protein binds to ANXA1 protein modified form]]	10807665
D015735	Mifepristone	Mifepristone inhibits the reaction [Dexamethasone results in increased localization of ANXA1 protein modified form]	10807665
D015735	Mifepristone	Mifepristone inhibits the reaction [Dexamethasone results in increased phosphorylation of and results in increased expression of ANXA1 protein]	10807665
D015735	Mifepristone	Mifepristone inhibits the reaction [Hydrocortisone results in increased expression of ANXA1 mRNA]	25763180
D015735	Mifepristone	Mifepristone results in increased expression of ANXA1 mRNA	17584828
C523799	MRK 003	ANXA1 results in increased susceptibility to MRK 003	19903844
D009151	Mustard Gas	Mustard Gas results in increased expression of ANXA1 mRNA	18988085
D037742	Nanotubes, Carbon	"Nanotubes, Carbon results in increased expression of ANXA1 protein"	22157353
D037742	Nanotubes, Carbon	"Nanotubes, Carbon analog results in increased expression of ANXA1 mRNA"	25554681
D037742	Nanotubes, Carbon	"Nanotubes, Carbon results in increased expression of ANXA1 mRNA"	25554681
D015058	1-Naphthylisothiocyanate	1-Naphthylisothiocyanate results in increased expression of ANXA1 mRNA	25380136
C029938	nickel sulfate	nickel sulfate results in increased expression of ANXA1 mRNA	16314067
D009538	Nicotine	Nicotine results in decreased expression of ANXA1 mRNA	26776438
C014707	nitrosobenzylmethylamine	nitrosobenzylmethylamine results in increased expression of ANXA1 mRNA	17616710
D009638	Norepinephrine	ANXA1 affects the reaction [Norepinephrine results in decreased secretion of IL6 protein]	16835395
C025589	ochratoxin A	ochratoxin A results in increased expression of ANXA1 mRNA	23358140
C030110	oxaliplatin	oxaliplatin results in increased expression of ANXA1 mRNA	25729387
D010100	Oxygen	Oxygen affects the reaction [AHR protein results in increased expression of ANXA1 mRNA]	27103661
D010126	Ozone	Ozone results in increased expression of ANXA1 mRNA	12763052
D017239	Paclitaxel	ANXA1 protein results in increased susceptibility to Paclitaxel	16734730
C496932	panobinostat	panobinostat results in increased expression of ANXA1 mRNA	26272509
D010269	Paraquat	Paraquat results in increased expression of ANXA1 protein	24521700
D052638	Particulate Matter	Particulate Matter results in increased expression of ANXA1 protein	17520064
D010396	Penicillamine	Penicillamine results in decreased expression of ANXA1 mRNA	19575532
D010396	Penicillamine	Penicillamine results in increased expression of ANXA1 mRNA	19575532
C086401	pentabromodiphenyl ether	pentabromodiphenyl ether results in decreased expression of ANXA1 mRNA	23948077
C023036	perfluorooctanoic acid	perfluorooctanoic acid results in increased expression of ANXA1 mRNA	16221955
D015232	Dinoprostone	ANXA1 protein inhibits the reaction [Lipopolysaccharides results in increased abundance of Dinoprostone]	21777521
D010634	Phenobarbital	Phenobarbital affects the expression of ANXA1 mRNA	19159669
D010634	Phenobarbital	[Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of ANXA1 protein	20935162
D010662	Phenylmercuric Acetate	"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ANXA1 mRNA"	27188386
D010662	Phenylmercuric Acetate	Phenylmercuric Acetate results in increased expression of ANXA1 mRNA	26272509
D010705	Phosgene	Phosgene affects the expression of ANXA1 mRNA	16300373
D011189	Potassium Chloride	"[Desoxycorticosterone Acetate co-treated with Sodium Chloride, Dietary co-treated with Potassium Chloride] results in increased expression of ANXA1 mRNA"	22228705
D011192	Potassium Dichromate	Potassium Dichromate results in increased expression of ANXA1 protein	18563748
D011374	Progesterone	Progesterone results in decreased expression of ANXA1 mRNA	23018184
C015586	propiverine	propiverine binds to ANXA1 protein	29273565
D011441	Propylthiouracil	Propylthiouracil results in increased expression of ANXA1 mRNA	24780913
C513428	pyrachlostrobin	pyrachlostrobin results in increased expression of ANXA1 mRNA	27029645
D011794	Quercetin	[Quercetin co-treated with Ascorbic Acid] results in increased expression of ANXA1 mRNA	17639512
D011794	Quercetin	Quercetin results in increased expression of ANXA1 protein	15221776
D011794	Quercetin	Quercetin results in decreased expression of ANXA1 mRNA	18095365
C037219	quinoline	quinoline analog results in increased expression of ANXA1 protein	18645022
C059514	resveratrol	resveratrol results in increased expression of ANXA1 mRNA	25866375
C059514	resveratrol	resveratrol results in decreased expression of ANXA1 protein	25505154
C089032	rimonabant	rimonabant inhibits the reaction [Dietary Fats results in increased expression of ANXA1 mRNA]	19030233
C116926	rofecoxib	rofecoxib affects the expression of ANXA1 mRNA	17070997
C089730	rosiglitazone	rosiglitazone affects the expression of ANXA1 protein	19556978
C541923	sandostatinLAR	sandostatinLAR results in increased expression of ANXA1 mRNA	17210224
D012822	Silicon Dioxide	Silicon Dioxide analog affects the secretion of ANXA1 protein	25895662
D012822	Silicon Dioxide	Silicon Dioxide results in increased expression of ANXA1 mRNA	23221170
D012834	Silver	Silver results in increased expression of ANXA1 mRNA	28959546
D019821	Simvastatin	Simvastatin results in increased expression of ANXA1 protein	14973129
C017947	sodium arsenite	sodium arsenite results in increased expression of ANXA1 protein	15899475
D017673	Sodium Chloride, Dietary	"[Desoxycorticosterone Acetate co-treated with Sodium Chloride, Dietary co-treated with Potassium Chloride] results in increased expression of ANXA1 mRNA"	22228705
D012969	Sodium Fluoride	Sodium Fluoride results in increased expression of ANXA1 protein	27548804
D018038	Sodium Selenite	Sodium Selenite results in increased expression of ANXA1 mRNA	18175754
D053260	Soot	Soot results in increased expression of ANXA1 mRNA	26551751
D010042	Ouabain	Ouabain affects the expression of ANXA1 protein	17268060
C016766	sulforafan	sulforafan results in increased expression of ANXA1 mRNA	26833863
D016559	Tacrolimus	Tacrolimus results in increased expression of ANXA1	20484890
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin affects the expression of ANXA1 mRNA	22298810
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin results in increased expression of ANXA1 mRNA	20067830
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin affects the expression of ANXA1 mRNA	21570461
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin results in decreased expression of ANXA1 mRNA	15667827\|1977048
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin results in increased expression of ANXA1 mRNA	15591033\|1703548
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin results in increased expression of ANXA1 mRNA	16267337
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin affects the expression of ANXA1 mRNA	22298810
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin results in increased expression of ANXA1 mRNA	20959002\|2121527
D013755	Tetradecanoylphorbol Acetate	Tetradecanoylphorbol Acetate results in increased expression of ANXA1 mRNA	19945525
D013755	Tetradecanoylphorbol Acetate	[Tetradecanoylphorbol Acetate co-treated with Ionomycin] affects the expression of ANXA1 mRNA	25613284
D013853	Thioacetamide	[Diethylnitrosamine co-treated with Thioacetamide] results in increased expression of ANXA1 mRNA	28943392
D013876	Thiophenes	Thiophenes analog promotes the reaction [Tretinoin results in increased expression of ANXA1 mRNA]	16140955
D014028	Tobacco Smoke Pollution	Tobacco Smoke Pollution results in increased metabolism of ANXA1 protein	23396223
C483909	torcetrapib	torcetrapib results in increased expression of ANXA1 mRNA	23228038
D014212	Tretinoin	Thiophenes analog promotes the reaction [Tretinoin results in increased expression of ANXA1 mRNA]	16140955
D014212	Tretinoin	Tretinoin results in decreased expression of ANXA1 mRNA	23830798
D014212	Tretinoin	Tretinoin results in decreased expression of ANXA1 protein	28886987
D014212	Tretinoin	Tretinoin results in increased expression of ANXA1 mRNA	15982314\|1614095
D014212	Tretinoin	Tretinoin results in increased expression of ANXA1 mRNA	24977338
C032910	triadimefon	triadimefon results in decreased expression of ANXA1 mRNA	26705709
C012589	trichostatin A	"[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ANXA1 mRNA"	27188386
C012589	trichostatin A	trichostatin A results in increased expression of ANXA1 mRNA	24935251\|2627250
C012589	trichostatin A	trichostatin A results in decreased expression of ANXA1 mRNA	15901671
D014302	Trinitrobenzenesulfonic Acid	Trinitrobenzenesulfonic Acid results in increased expression of ANXA1 mRNA	17982090
C057693	troglitazone	troglitazone results in increased expression of ANXA1 mRNA	28973697
D014635	Valproic Acid	Valproic Acid affects the expression of ANXA1 mRNA	25979313\|2607246
D014635	Valproic Acid	Valproic Acid results in decreased methylation of ANXA1 gene	29154799
D014635	Valproic Acid	Valproic Acid results in increased expression of ANXA1 mRNA	23179753\|2438349
D014635	Valproic Acid	Valproic Acid affects the expression of ANXA1 mRNA	26072468
D014635	Valproic Acid	Valproic Acid results in decreased expression of ANXA1 mRNA	15901671
D014640	Vancomycin	Vancomycin results in decreased expression of ANXA1 mRNA	18930951
D001335	Vehicle Emissions	Vehicle Emissions results in increased expression of ANXA1 protein	17520064
C025643	vinclozolin	vinclozolin affects the expression of ANXA1 mRNA	19015723
C025643	vinclozolin	vinclozolin results in increased methylation of ANXA1 promoter	20927350
D014750	Vincristine	Vincristine results in increased expression of ANXA1 mRNA	23649840
C029297	vinylidene chloride	vinylidene chloride results in increased expression of ANXA1 mRNA	26682919
D015032	Zinc	Zinc affects the expression of ANXA1 mRNA	16979875
D015034	Zinc Oxide	Zinc Oxide analog results in increased expression of ANXA1 mRNA	27215404
D015054	Zymosan	ANXA1 gene mutant form results in decreased export of Zymosan	16633358
D015054	Zymosan	ANXA1 gene mutant form results in decreased uptake of Zymosan	16633358
D015054	Zymosan	ANXA1 protein affects the reaction [Zymosan affects the secretion of TNF protein]	16633358
D015054	Zymosan	ANXA1 protein affects the susceptibility to Zymosan	12475898
D015054	Zymosan	ANXA1 protein results in increased uptake of Zymosan	12475898

GO/Pathway

GO ID	GO Term	Qualifier	Evidence	PubMed
GO:0003697	single-stranded DNA binding	-	IEA	-
GO:0003727	single-stranded RNA binding	-	IEA	-
GO:0005102	signaling receptor binding	-	TAS	10882119
GO:0005198	structural molecule activity	-	IDA	10908733
GO:0005509	calcium ion binding	-	ISS	-
GO:0005515	protein binding	-	IPI	15581623 20029029 21383699 24189400
GO:0005543	phospholipid binding	-	TAS	2967291
GO:0005544	calcium-dependent phospholipid binding	-	IDA	2138016
GO:0019834	phospholipase A2 inhibitor activity	-	IDA	2936963 3013422
GO:0030674	protein binding, bridging	-	IDA	10908733
GO:0033676	double-stranded DNA-dependent ATPase activity	-	IEA	-
GO:0042803	protein homodimerization activity	-	IEA	-
GO:0048306	calcium-dependent protein binding	-	IPI	15226301
GO:0098641	cadherin binding involved in cell-cell adhesion	-	HDA	25468996
GO:1990814	DNA/DNA annealing activity	-	IEA	-

GO ID	GO Term	Qualifier	Evidence	PubMed
GO:0001780	neutrophil homeostasis	-	IMP	21957127
GO:0002250	adaptive immune response	-	IEA	-
GO:0002548	monocyte chemotaxis	-	IDA	15187149
GO:0002685	regulation of leukocyte migration	-	ISS	-
GO:0006909	phagocytosis	-	ISS	-
GO:0006954	inflammatory response	-	ISS	-
GO:0007165	signal transduction	-	TAS	16130169
GO:0007166	cell surface receptor signaling pathway	-	TAS	10882119
GO:0007186	G-protein coupled receptor signaling pathway	-	TAS	-
GO:0007187	G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger	-	IDA	25664854
GO:0007187	G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger	-	IMP	15187149
GO:0008360	regulation of cell shape	-	IDA	15187149
GO:0010165	response to X-ray	-	IEA	-
GO:0014839	myoblast migration involved in skeletal muscle regeneration	-	IEA	-
GO:0018149	peptide cross-linking	-	IDA	10908733
GO:0019221	cytokine-mediated signaling pathway	-	TAS	-
GO:0030073	insulin secretion	-	IEA	-
GO:0030216	keratinocyte differentiation	-	IDA	10908733
GO:0030850	prostate gland development	-	IEA	-
GO:0031018	endocrine pancreas development	-	IEA	-
GO:0031340	positive regulation of vesicle fusion	-	IDA	2138016
GO:0031394	positive regulation of prostaglandin biosynthetic process	-	IEA	-
GO:0031532	actin cytoskeleton reorganization	-	IDA	15187149
GO:0032355	response to estradiol	-	IEA	-
GO:0032508	DNA duplex unwinding	-	IEA	-
GO:0032652	regulation of interleukin-1 production	-	ISS	-
GO:0032743	positive regulation of interleukin-2 production	-	IDA	17008549
GO:0033031	positive regulation of neutrophil apoptotic process	-	IEA	-
GO:0035924	cellular response to vascular endothelial growth factor stimulus	-	IDA	22773844
GO:0042063	gliogenesis	-	IEA	-
GO:0042102	positive regulation of T cell proliferation	-	IDA	17008549
GO:0043066	negative regulation of apoptotic process	-	TAS	16130169
GO:0043434	response to peptide hormone	-	IEA	-
GO:0044849	estrous cycle	-	IEA	-
GO:0045087	innate immune response	-	IEA	-
GO:0045627	positive regulation of T-helper 1 cell differentiation	-	IDA	17008549
GO:0045629	negative regulation of T-helper 2 cell differentiation	-	IDA	17008549
GO:0045920	negative regulation of exocytosis	-	IMP	19625660
GO:0046632	alpha-beta T cell differentiation	-	ISS	-
GO:0046883	regulation of hormone secretion	-	IMP	19625660
GO:0050482	arachidonic acid secretion	-	IEA	-
GO:0050727	regulation of inflammatory response	-	ISS	-
GO:0070301	cellular response to hydrogen peroxide	-	IEA	-
GO:0070365	hepatocyte differentiation	-	IEA	-
GO:0070459	prolactin secretion	-	IEA	-
GO:0070555	response to interleukin-1	-	IEA	-
GO:0071385	cellular response to glucocorticoid stimulus	-	IDA	2936963
GO:0071621	granulocyte chemotaxis	-	IDA	15187149
GO:0090050	positive regulation of cell migration involved in sprouting angiogenesis	-	IDA	22773844
GO:0090303	positive regulation of wound healing	-	IDA	25664854
GO:0097350	neutrophil clearance	-	IMP	21957127
GO:0098609	cell-cell adhesion	-	IEA	-
GO:1900087	positive regulation of G1/S transition of mitotic cell cycle	-	IEA	-
GO:1900138	negative regulation of phospholipase A2 activity	-	IEA	-
GO:2000483	negative regulation of interleukin-8 secretion	-	IMP	22056994

GO ID	GO Term	Qualifier	Evidence	PubMed
GO:0001533	cornified envelope	-	IDA	10908733
GO:0001891	phagocytic cup	-	IEA	-
GO:0005576	extracellular region	-	TAS	-
GO:0005615	extracellular space	-	HDA	22664934 23580065
GO:0005615	extracellular space	-	IDA	17008549 19625660 25664854
GO:0005634	nucleus	-	IDA	22056994
GO:0005654	nucleoplasm	-	IDA	-
GO:0005737	cytoplasm	-	IDA	17008549 19625660 22056994
GO:0005737	cytoplasm	-	TAS	16130169
GO:0005768	endosome	-	IDA	18767904
GO:0005829	cytosol	-	IDA	-
GO:0005884	actin filament	colocalizes_with	IDA	22773844
GO:0005886	plasma membrane	-	IDA	-
GO:0005913	cell-cell adherens junction	-	HDA	25468996
GO:0005925	focal adhesion	-	HDA	21423176
GO:0009986	cell surface	-	IDA	22056994
GO:0016323	basolateral plasma membrane	-	IEA	-
GO:0016324	apical plasma membrane	-	ISS	-
GO:0016328	lateral plasma membrane	-	ISS	-
GO:0019898	extrinsic component of membrane	-	IDA	17008549
GO:0030659	cytoplasmic vesicle membrane	-	IEA	-
GO:0031232	extrinsic component of external side of plasma membrane	-	IDA	19625660
GO:0031313	extrinsic component of endosome membrane	-	ISS	-
GO:0031514	motile cilium	-	ISS	-
GO:0031901	early endosome membrane	-	ISS	-
GO:0031966	mitochondrial membrane	-	IEA	-
GO:0031982	vesicle	-	HDA	19190083
GO:0032991	protein-containing complex	-	IEA	-
GO:0042383	sarcolemma	-	IEA	-
GO:0042629	mast cell granule	-	IEA	-
GO:0070062	extracellular exosome	-	HDA	19056867 19199708 21362503 23533145
GO:0070062	extracellular exosome	-	IDA	25664854

KEGG ID	KEGG Term

Reactome ID	Reactome Term	Evidence
R-HSA-1280215	Cytokine Signaling in Immune system	TAS
R-HSA-162582	Signal Transduction	TAS
R-HSA-168256	Immune System	TAS
R-HSA-372790	Signaling by GPCR	TAS
R-HSA-373076	Class A/1 (Rhodopsin-like receptors)	TAS
R-HSA-375276	Peptide ligand-binding receptors	TAS
R-HSA-388396	GPCR downstream signalling	TAS
R-HSA-397014	Muscle contraction	IEA
R-HSA-416476	G alpha (q) signalling events	TAS
R-HSA-418594	G alpha (i) signalling events	TAS
R-HSA-444473	Formyl peptide receptors bind formyl peptides and many other ligands	TAS
R-HSA-445355	Smooth Muscle Contraction	IEA
R-HSA-449147	Signaling by Interleukins	TAS
R-HSA-500792	GPCR ligand binding	TAS
R-HSA-6785807	Interleukin-4 and 13 signaling	TAS

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID	Title (Year)	Author	Journal
24453033	Detection of circulating antibodies to linear peptide antigens derived from ANXA1 and DDX53 in lung cancer. (2014 May)	Wang W	Tumour Biol
23341933	Overexpression of ANXA1 in penile carcinomas positive for high-risk HPVs. (2013)	Calmon MF	PLoS One