| SNP ID | Position | Alleles | Trait | Variation Type |
|---|---|---|---|---|
| rs1800562 | chr6:26092913 (GRCh38.p7) | G>A | alcohol dependence | SNV(Single Nucleotide Variation) |
| Gene Symbol | Pearson Correlation Coefficient |
|---|---|
| CD302 | 0.848 |
| TGFBR3 | 0.819 |
| CD109 | 0.806 |
| CDC14A | 0.801 |
| LEPROT | 0.8 |
| RREB1 | 0.798 |
| SULT1C4 | 0.797 |
| AHNAK | 0.797 |
| CYBRD1 | 0.794 |
| ITPR2 | 0.792 |
| Gene Symbol | Pearson Correlation Coefficient |
|---|---|
| GALNT14 | -0.518 |
| ABCC12 | -0.48 |
| BCL11A | -0.474 |
| KCNB2 | -0.472 |
| HAS1 | -0.469 |
| MRAP2 | -0.467 |
| RHO | -0.464 |
| MCHR1 | -0.462 |
| B3GNT4 | -0.457 |
| CALHM1 | -0.456 |
| ID | Drug Name | Action | PubMed |
|---|---|---|---|
| C496492 | abrine | abrine results in increased expression of HFE mRNA | 22595364 |
| D000082 | Acetaminophen | Acetaminophen results in decreased expression of HFE mRNA | 29067470 |
| D000082 | Acetaminophen | Acetaminophen affects the expression of HFE mRNA | 17562736 |
| D020106 | Acrylamide | Acrylamide results in increased expression of HFE mRNA | 28959563 |
| D000393 | Air Pollutants | Air Pollutants analog results in decreased expression of HFE mRNA | 21757418 |
| D000393 | Air Pollutants | HFE gene polymorphism affects the susceptibility to Air Pollutants | 20194081 |
| D000643 | Ammonium Chloride | Ammonium Chloride affects the expression of HFE mRNA | 16483693 |
| D018501 | Antirheumatic Agents | Antirheumatic Agents results in decreased expression of HFE mRNA | 24449571 |
| C006632 | arsenic trioxide | HFE protein results in decreased susceptibility to arsenic trioxide | 20707922 |
| D001280 | Atrazine | Atrazine results in decreased expression of HFE mRNA | 25929836 |
| D001564 | Benzo(a)pyrene | Benzo(a)pyrene results in increased expression of HFE mRNA | 19770486|2222880 |
| D004958 | Estradiol | Estradiol affects the expression of HFE mRNA | 16684588 |
| C006780 | bisphenol A | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of HFE mRNA | 28628672 |
| C006780 | bisphenol A | bisphenol A affects the expression of HFE mRNA | 25181051 |
| C018475 | butyraldehyde | butyraldehyde results in decreased expression of HFE mRNA | 26079696 |
| D019256 | Cadmium Chloride | Cadmium Chloride results in increased expression of HFE mRNA | 21540277 |
| C030583 | ceric oxide | ceric oxide analog results in decreased expression of HFE mRNA | 24821434 |
| C012843 | cinnamic aldehyde | cinnamic aldehyde results in increased expression of HFE mRNA | 19524605 |
| C018021 | cobaltous chloride | cobaltous chloride results in decreased expression of HFE mRNA | 19376846 |
| C060728 | cobalt oxide | cobalt oxide analog results in increased expression of HFE mRNA | 24821434 |
| D003300 | Copper | Copper results in increased expression of HFE mRNA | 16629173 |
| D003300 | Copper | HFE protein affects the abundance of Copper | 18317567 |
| D016572 | Cyclosporine | Cyclosporine results in increased expression of HFE mRNA | 22147139 |
| C010902 | decabromobiphenyl ether | decabromobiphenyl ether results in increased expression of HFE mRNA | 23914054 |
| D003907 | Dexamethasone | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of HFE mRNA | 28628672 |
| D002945 | Cisplatin | [Cisplatin co-treated with jinfukang] results in increased expression of HFE mRNA | 27392435 |
| D018119 | Stavudine | HFE gene SNP affects the susceptibility to [Didanosine co-treated with Stavudine] | 16847405 |
| D016049 | Didanosine | HFE gene SNP affects the susceptibility to [Didanosine co-treated with Stavudine] | 16847405 |
| D004317 | Doxorubicin | HFE protein inhibits the reaction [Doxorubicin results in increased activity of CASP3 protein] | 16823846 |
| C118739 | entinostat | entinostat results in increased expression of HFE mRNA | 27188386 |
| D004997 | Ethinyl Estradiol | Ethinyl Estradiol affects the expression of HFE mRNA | 17555576 |
| D004997 | Ethinyl Estradiol | Ethinyl Estradiol results in increased expression of HFE mRNA | 17942748 |
| D004997 | Ethinyl Estradiol | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of HFE mRNA | 17942748 |
| D005038 | Ethylnitrosourea | Ethylnitrosourea results in increased mutagenesis of HFE mRNA | 27776689 |
| D028441 | F2-Isoprostanes | [HFE gene mutant form co-treated with TFR2 gene mutant form] results in increased abundance of F2-Isoprostanes | 22383097 |
| D028441 | F2-Isoprostanes | HFE gene mutant form results in increased abundance of F2-Isoprostanes | 22383097 |
| D005839 | Gentamicins | Gentamicins results in increased expression of HFE mRNA | 22061828 |
| D005978 | Glutathione | Glutathione deficiency results in increased expression of HFE mRNA | 15345336 |
| D017313 | Fenretinide | Fenretinide results in decreased expression of HFE mRNA | 28973697 |
| D006830 | Hydralazine | [Hydralazine co-treated with Valproic Acid] results in increased expression of HFE mRNA | 17183730 |
| D007213 | Indomethacin | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of HFE mRNA | 28628672 |
| D007501 | Iron | HFE gene mutant form results in increased abundance of Iron | 17101320 |
| D007501 | Iron | HFE gene mutant form results in increased uptake of Iron | 17101320 |
| D007501 | Iron | HFE gene polymorphism affects the abundance of Iron | 16877869 |
| D007501 | Iron | HFE gene polymorphism results in increased abundance of Iron | 17047092 |
| D007501 | Iron | HFE protein affects the abundance of Iron | 12393473 |
| D007501 | Iron | HFE protein affects the susceptibility to Iron | 16893896 |
| D007501 | Iron | [HFE protein binds to B2M protein binds to SLC11A2 protein] which results in decreased uptake of Iron | 16841247 |
| D007501 | Iron | [HFE protein binds to TFR2 protein] which affects the susceptibility to Iron | 16893896 |
| D007501 | Iron | HFE protein inhibits the reaction [TFRC protein results in increased uptake of Iron] | 10085150 |
| D007501 | Iron | HFE protein results in decreased uptake of Iron | 16823846|1684124 |
| D007501 | Iron | TNF gene SNP promotes the reaction [HFE protein mutant form results in increased uptake of Iron] | 16793930 |
| D007501 | Iron | [HFE gene mutant form co-treated with TFR2 gene mutant form] results in increased abundance of Iron | 22383097 |
| D007501 | Iron | HFE protein affects the abundance of Iron | 18317567 |
| D007501 | Iron | HFE protein affects the metabolism of Iron | 17194590 |
| D015056 | 1-Methyl-3-isobutylxanthine | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of HFE mRNA | 28628672 |
| D007545 | Isoproterenol | Isoproterenol results in increased expression of HFE mRNA | 20003209 |
| C544151 | jinfukang | [Cisplatin co-treated with jinfukang] results in increased expression of HFE mRNA | 27392435 |
| C544151 | jinfukang | jinfukang results in increased expression of HFE mRNA | 27392435 |
| D007854 | Lead | HFE gene polymorphism affects the susceptibility to Lead | 19165391|2596350 |
| D007854 | Lead | HFE protein polymorphism results in increased susceptibility to Lead | 20478760 |
| D007854 | Lead | HFE gene polymorphism affects the susceptibility to Lead | 20659343 |
| C008261 | lead acetate | lead acetate results in decreased expression of HFE mRNA | 21829687 |
| D008054 | Lipid Peroxides | [HFE gene mutant form co-treated with TFR2 gene mutant form] results in increased abundance of Lipid Peroxides | 22383097 |
| D058185 | Magnetite Nanoparticles | [Succimer co-treated with Magnetite Nanoparticles] results in decreased expression of HFE mRNA | 26378955 |
| D008345 | Manganese | HFE protein affects the abundance of Manganese | 18317567 |
| C025340 | manganese chloride | HFE gene mutant form inhibits the reaction [manganese chloride results in decreased activity of SOD1 protein] | 25874029 |
| C025340 | manganese chloride | HFE gene mutant form results in decreased susceptibility to manganese chloride | 25874029 |
| D037742 | Nanotubes, Carbon | "Nanotubes, Carbon results in decreased expression of HFE mRNA" | 25554681 |
| C051752 | nefazodone | nefazodone results in increased expression of HFE mRNA | 24136188 |
| D010634 | Phenobarbital | Phenobarbital results in increased expression of HFE mRNA | 19162173 |
| C006253 | pirinixic acid | pirinixic acid results in increased expression of HFE mRNA | 19162173 |
| D011285 | Pregnenolone Carbonitrile | Pregnenolone Carbonitrile results in increased expression of HFE mRNA | 19162173 |
| C045950 | propiconazole | propiconazole results in increased expression of HFE mRNA | 21278054 |
| C005556 | propionaldehyde | propionaldehyde results in decreased expression of HFE mRNA | 26079696 |
| D012822 | Silicon Dioxide | Silicon Dioxide results in increased expression of HFE mRNA | 23221170 |
| D012834 | Silver | Silver results in increased expression of HFE mRNA | 27131904 |
| D012906 | Smoke | Smoke results in decreased expression of HFE mRNA | 21095227 |
| C017947 | sodium arsenite | sodium arsenite results in increased expression of HFE mRNA | 22714537 |
| D053260 | Soot | HFE gene polymorphism affects the susceptibility to Soot | 20194081 |
| D004113 | Succimer | [Succimer co-treated with Magnetite Nanoparticles] results in decreased expression of HFE mRNA | 26378955 |
| D013749 | Tetrachlorodibenzodioxin | Tetrachlorodibenzodioxin affects the expression of HFE mRNA | 21570461 |
| D013749 | Tetrachlorodibenzodioxin | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of HFE mRNA | 17942748 |
| D013749 | Tetrachlorodibenzodioxin | Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to HFE gene] | 28213091 |
| D013749 | Tetrachlorodibenzodioxin | Tetrachlorodibenzodioxin results in decreased expression of HFE mRNA | 28213091 |
| D013853 | Thioacetamide | Thioacetamide results in decreased expression of HFE mRNA | 23411599 |
| C483909 | torcetrapib | torcetrapib results in increased expression of HFE mRNA | 23228038 |
| C032910 | triadimefon | triadimefon results in increased expression of HFE mRNA | 16730040 |
| D014635 | Valproic Acid | [Hydralazine co-treated with Valproic Acid] results in increased expression of HFE mRNA | 17183730 |
| D001335 | Vehicle Emissions | HFE gene polymorphism affects the susceptibility to Vehicle Emissions | 20194081 |
| D001335 | Vehicle Emissions | Vehicle Emissions results in increased methylation of HFE gene | 25560391 |
| D015032 | Zinc | HFE protein affects the abundance of Zinc | 18317567 |
| C017803 | zinc protoporphyrin | HFE gene polymorphism affects the abundance of zinc protoporphyrin | 25963508 |
| GO ID | GO Term | Qualifier | Evidence | PubMed |
|---|---|---|---|---|
| GO:0005102 | signaling receptor binding | - | IPI | 10638746 24904118 |
| GO:0005515 | protein binding | - | IPI | 15880641 15965644 20618438 |
| GO:0030881 | beta-2-microglobulin binding | - | IPI | 9465039 9546397 9990067 |
| GO:0039706 | co-receptor binding | - | IPI | 22728873 |
| GO:0042605 | peptide antigen binding | NOT | IDA | 9546397 |
| GO:0042605 | peptide antigen binding | NOT | IKR | 8696333 |
| GO:0046703 | natural killer cell lectin-like receptor binding | - | IBA | 21873635 |
| GO:1990459 | transferrin receptor binding | - | IPI | 9465039 9546397 9990067 18353247 22728873 |
| GO ID | GO Term | Qualifier | Evidence | PubMed |
|---|---|---|---|---|
| GO:0001913 | T cell mediated cytotoxicity | - | IBA | 21873635 |
| GO:0002474 | antigen processing and presentation of peptide antigen via MHC class I | NOT | IKR | 8696333 |
| GO:0002626 | negative regulation of T cell antigen processing and presentation | - | IEA | - |
| GO:0002725 | negative regulation of T cell cytokine production | - | IGI | 24643698 |
| GO:0006879 | cellular iron ion homeostasis | - | TAS | 10638746 |
| GO:0006953 | acute-phase response | - | IEA | - |
| GO:0006955 | immune response | - | IBA | 21873635 |
| GO:0007565 | female pregnancy | - | IEA | - |
| GO:0010039 | response to iron ion | - | IMP | 21173098 |
| GO:0010106 | cellular response to iron ion starvation | - | IEA | - |
| GO:0010628 | positive regulation of gene expression | - | ISS | - |
| GO:0010862 | positive regulation of pathway-restricted SMAD protein phosphorylation | - | IDA | 24904118 |
| GO:0019882 | antigen processing and presentation | NOT | IC | 9546397 |
| GO:0030101 | natural killer cell activation | - | IBA | 21873635 |
| GO:0030509 | BMP signaling pathway | - | IDA | 24904118 |
| GO:0032092 | positive regulation of protein binding | - | IGI | 18353247 |
| GO:0032435 | negative regulation of proteasomal ubiquitin-dependent protein catabolic process | - | IC | 24904118 |
| GO:0033572 | transferrin transport | - | TAS | - |
| GO:0042267 | natural killer cell mediated cytotoxicity | - | IBA | 21873635 |
| GO:0042271 | susceptibility to natural killer cell mediated cytotoxicity | - | IBA | 21873635 |
| GO:0042446 | hormone biosynthetic process | - | IEA | - |
| GO:0048260 | positive regulation of receptor-mediated endocytosis | - | IGI | 18353247 |
| GO:0055072 | iron ion homeostasis | - | IC | 18353247 |
| GO:0055072 | iron ion homeostasis | - | IMP | 21173098 |
| GO:0060586 | multicellular organismal iron ion homeostasis | - | IEA | - |
| GO:0065003 | protein-containing complex assembly | - | TAS | 10638746 |
| GO:0071281 | cellular response to iron ion | - | IGI | 18353247 |
| GO:0090277 | positive regulation of peptide hormone secretion | - | IMP | 21173098 |
| GO:0097421 | liver regeneration | - | IEA | - |
| GO:0098711 | iron ion import across plasma membrane | - | IDA | 10085150 |
| GO:1900121 | negative regulation of receptor binding | - | IDA | 9465039 |
| GO:1900122 | positive regulation of receptor binding | - | IGI | 18353247 |
| GO:1900390 | regulation of iron ion import | - | IGI | 18353247 |
| GO:1904283 | negative regulation of antigen processing and presentation of endogenous peptide antigen via MHC class I | - | IGI | 24643698 |
| GO:1904434 | positive regulation of ferrous iron binding | - | IGI | 18353247 |
| GO:1904437 | positive regulation of transferrin receptor binding | - | IGI | 18353247 |
| GO:1990641 | response to iron ion starvation | - | IEA | - |
| GO:2000008 | regulation of protein localization to cell surface | - | IMP | 12704209 |
| GO:2000059 | negative regulation of ubiquitin-dependent protein catabolic process | - | IDA | 24904118 |
| GO:2000272 | negative regulation of signaling receptor activity | - | IDA | 9465039 |
| GO:2000273 | positive regulation of signaling receptor activity | - | IGI | 18353247 |
| GO:2001186 | negative regulation of CD8-positive, alpha-beta T cell activation | - | IGI | 24643698 |
| GO ID | GO Term | Qualifier | Evidence | PubMed |
|---|---|---|---|---|
| GO:0005615 | extracellular space | - | IDA | 21173098 |
| GO:0005769 | early endosome | - | IDA | 15880641 |
| GO:0005886 | plasma membrane | - | IBA | 21873635 |
| GO:0005886 | plasma membrane | - | TAS | - |
| GO:0005887 | integral component of plasma membrane | - | TAS | 10638746 |
| GO:0009897 | external side of plasma membrane | - | IDA | 24904118 |
| GO:0031410 | cytoplasmic vesicle | - | IDA | 12704209 15880641 |
| GO:0042612 | MHC class I protein complex | NOT | IDA | 9546397 |
| GO:0042612 | MHC class I protein complex | NOT | IKR | 8696333 |
| GO:0045177 | apical part of cell | - | IDA | 15880641 |
| GO:0045178 | basal part of cell | - | IDA | 15880641 |
| GO:0048471 | perinuclear region of cytoplasm | - | IDA | 9990067 15880641 |
| GO:0055037 | recycling endosome | - | IDA | 15880641 |
| GO:1990357 | terminal web | - | IEA | - |
| GO:1990712 | HFE-transferrin receptor complex | - | IDA | 9465039 9546397 9990067 12704209 22728873 |
| KEGG ID | KEGG Term |
|---|
| Reactome ID | Reactome Term | Evidence |
|---|---|---|
| R-HSA-382551 | Transport of small molecules | TAS |
| R-HSA-917937 | Iron uptake and transport | TAS |
| R-HSA-917977 | Transferrin endocytosis and recycling | TAS |
| PMID | Title (Year) | Author | Journal |
|---|---|---|---|
| 22422567 | Clinical cofactors and hepatic fibrosis in hereditary hemochromatosis: the role of diabetes mellitus. (2012 Sep) | Wood MJ | Hepatology |
| 11257277 | A prospective study of coronary heart disease and the hemochromatosis gene (HFE) C282Y mutation: the Atherosclerosis Risk in Communities (ARIC) study. (2001 Feb 15) | Rasmussen ML | Atherosclerosis |
| 20640879 | HFE gene mutations increase the risk of coronary heart disease in women. (2010 Sep) | Pardo Silva MC | Eur J Epidemiol |
| 12948285 | Heterozygosity for the Cys282Tyr mutation in the HFE gene and the risk of colorectal cancer (Netherlands). (2003 Aug) | van der A DL | Cancer Causes Control |
| 11886425 | Haemochromatosis mutations and ferritin in myocardial infarction: a case-control study. (2002 Mar) | Claeys D | Eur J Clin Invest |
| 12364722 | Mutations in the hemochromatosis gene (HFE) and stroke. (2002 Oct) | Njajou OT | Stroke |
| 22510500 | Hepatitis C, porphyria cutanea tarda and liver iron: an update. (2012 Jul) | Ryan Caballes F | Liver Int |
| 23646229 | Lymphocyte subsets in alcoholic liver disease. (2013 Feb 27) | Matos LC | World J Hepatol |
| 15990686 | Hemochromatosis-causing mutations C282Y and H63D are not risk factors for atherothrombotic cerebral infarction. (2005 Jul) | Hruskovicova H | Med Sci Monit |
| 15139402 | [Hemochromatosis: the most common of rare diseases]. (2004 Mar) | Thielen V | Rev Med Liege |
| 20478760 | HFE H63D polymorphism as a modifier of the effect of cumulative lead exposure on pulse pressure: the Normative Aging Study. (2010 Sep) | Zhang A | Environ Health Perspect |
| 24988074 | The effect of the hemochromatosis (HFE) genotype on lead load and iron metabolism among lead smelter workers. (2014) | Fan G | PLoS One |
| 11855561 | Porphyria cutanea tarda: multiplicity of risk factors including HFE mutations, hepatitis C, and inherited uroporphyrinogen decarboxylase deficiency. (2002 Feb) | Egger NG | Dig Dis Sci |
| 10491369 | Heterozygosity for a hereditary hemochromatosis gene is associated with cardiovascular death in women. (1999 Sep 21) | Roest M | Circulation |
| 20101754 | Hemochromatosis in Italy in the last 30 years: role of genetic and acquired factors. (2010 Feb) | Fracanzani AL | Hepatology |
| 23681825 | Heme-related gene expression signatures of meat intakes in lung cancer tissues. (2014 Jul) | Lam TK | Mol Carcinog |
| 27170390 | Pathogenesis, Diagnosis and Treatment of Hemochromatosis. (2016) | Zoller H | Dig Dis |
| 11505030 | Effects of alcohol consumption on indices of iron stores and of iron stores on alcohol intake markers. (2001 Jul) | Whitfield JB | Alcohol Clin Exp Res |
| 20957336 | CYP1A2*1F and GSTM1 alleles are associated with susceptibility to porphyria cutanea tarda. (2011 Mar-Apr) | Wickliffe JK | Mol Med |
| 12957297 | Hemochromatosis and alcoholic liver disease. (2003 Jun) | Fletcher LM | Alcohol |
| 22732356 | Liver hepcidin mRNA expression is inappropriately low in alcoholic patients compared with healthy controls. (2012 Oct) | Costa-Matos L | Eur J Gastroenterol Hepatol |
| 10068114 | Premalignant lesions and hepatocellular carcinoma in a non-cirrhotic alcoholic patient with iron overload and normal transferrin saturation. (1999 Feb) | Blanc JF | J Hepatol |
| 18657084 | Behavioral, biochemical, and genetic analysis of iron metabolism in high-intensity blood donors. (2008 Oct) | Mast AE | Transfusion |
| 20107990 | Effects of C282Y, H63D, and S65C HFE gene mutations, diet, and life-style factors on iron status in a general Mediterranean population from Tarragona, Spain. (2010 Aug) | Aranda N | Ann Hematol |
| 26474245 | The role of genetic factors in patients with hepatocellular carcinoma and iron overload - a prospective series of 234 patients. (2016 May) | Funakoshi N | Liver Int |
| 17687451 | Evidence of genetic effects on blood lead concentration. (2007 Aug) | Whitfield JB | Environ Health Perspect |
| 26121922 | Cumulative lead exposure is associated with reduced olfactory recognition performance in elderly men: The Normative Aging Study. (2015 Jul) | Grashow R | Neurotoxicology |
| 23990522 | Diabetes in first-degree family members: a predictor of type 2 diabetes in 159 nonscreening Alabama hemochromatosis probands with HFE C282Y homozygosity. (2014) | Barton JC | Diabetes Care |
| 14675248 | Absence of hemochromatosis associated Cys282Tyr HFE gene mutation and low frequency of hemochromatosis phenotype in nonalcoholic chronic liver disease patients in India. (2004 Jan) | Thakur V | J Gastroenterol Hepatol |
| 23281741 | Cancer risk in HFE C282Y homozygotes: results from the HUNT 2 study. (2013 Feb) | Asberg A | Scand J Gastroenterol |
| 14966054 | Haemochromatosis gene mutations and risk of coronary heart disease: a west of Scotland coronary prevention study (WOSCOPS) substudy. (2004 Mar) | Gunn IR | Heart |
| 24068123 | Precipitating factors of porphyria cutanea tarda in Brazil with emphasis on hemochromatosis gene (HFE) mutations. Study of 60 patients. (2013 Jul-Aug) | Vieira FM | An Bras Dermatol |
| 12170286 | [Hereditary hemochromatosis]. (2001 Jan-Mar) | Dantas W | Rev Gastroenterol Peru |
| 11084432 | [Premalignant lesions and hepatocellular carcinoma on non cirrhotic liver overloaded with iron]. (2000 Oct) | Attia A | Gastroenterol Clin Biol |
| 25822977 | Effect of C282Y genotype on self-reported musculoskeletal complications in hereditary hemochromatosis. (2015) | Camacho A | PLoS One |
| 17639389 | The relationship between iron overload and clinical characteristics in a Spanish cohort of 100 C282Y homozygous hemochromatosis patients. (2007 Nov) | Altes A | Ann Hematol |
| 19948245 | Associations among behavior-related susceptibility factors in porphyria cutanea tarda. (2010 Mar) | Jalil S | Clin Gastroenterol Hepatol |
| 18661088 | Association between iron overload and osteoporosis in patients with hereditary hemochromatosis. (2009 Apr) | Valenti L | Osteoporos Int |
| 25654085 | HFE genotyping in patients with elevated serum iron indices and liver diseases. (2015) | Evangelista AS | Biomed Res Int |
| 22469802 | Iron biomarkers in plasma, HFE genotypes, and the risk for colorectal cancer in a prospective setting. (2012 Mar) | Ekblom K | Dis Colon Rectum |
| 19034258 | Hereditary hemochromatosis. (2008 Dec) | Fix OK | Minerva Med |
| 15121519 | Association between hemochromatosis genotype and lead exposure among elderly men: the normative aging study. (2004 May) | Wright RO | Environ Health Perspect |
| 26840933 | [Porphyria cutanea tarda: the benefit of additional diagnostics]. (2016) | Vossen AR | Ned Tijdschr Geneeskd |