Gene: HIF1A

3091
HIF-1-alpha|HIF-1A|HIF-1alpha|HIF1|HIF1-ALPHA|MOP1|PASD8|bHLHe78
hypoxia inducible factor 1 subunit alpha
protein-coding
14q23.2
Ensembl:ENSG00000100644 MIM:603348 Vega:OTTHUMG00000140344 UniprotKB:Q16665
NG_029606.1
PubMed
ND
9   
NA (AD)  NA (ND)   (Frontal_Cortex)
2.567e-2 (AD)  1.664e-1 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
PNPLA80.901
SH3GLB10.859
LMAN10.856
MCMBP0.853
SSR30.848
RAP1B0.841
ARFGAP30.834
TMED100.833
TMED70.833
NMD30.831

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
OR4F5-0.588
OR4F29-0.556
LYPD8-0.22
EDN3-0.216
KCNG2-0.21
NOTUM-0.205
ABCC12-0.204
ADRA1D-0.191
LCN1-0.189
RERGL-0.187

Drugs/Compounds

ID Drug Name Drug Type CAS Num Status Role
DB01136CarvedilolSmall Molecule72956-09-3Approved|InvestigationalTarget
DB023422-MethoxyestradiolSmall Molecule362-07-2InvestigationalTarget
DB05959ENMD-1198Small Molecule864668-87-1InvestigationalTarget
DB06082PX-478Small Molecule685898-44-6InvestigationalTarget
DB08687FG-2216Small Molecule223387-75-5InvestigationalTarget
ID Drug Name Action PubMed
C496879103D5R103D5R inhibits the reaction [cobaltous chloride results in increased expression of HIF1A protein]15695405
C496879103D5R103D5R results in decreased expression of and results in decreased activity of HIF1A protein15695405
C496879103D5R103D5R results in decreased expression of HIF1A mRNA15695405
C0252051,10-phenanthroline"1,10-phenanthroline results in increased activity of HIF1A protein"19502547
C0252051,10-phenanthroline"4'-O-methylalpinumisoflavone inhibits the reaction [1,10-phenanthroline deficiency results in increased activity of HIF1A protein]"19091749
C0252051,10-phenanthroline"alpinumisoflavone inhibits the reaction [1,10-phenanthroline deficiency results in increased activity of HIF1A protein]"19091749
C0252051,10-phenanthroline"HIF1A protein promotes the reaction [1,10-phenanthroline results in increased expression of VEGFA protein]"19502547
C4327471,1-dimethylbutyl-1-deoxy-Delta(9)-THC"1,1-dimethylbutyl-1-deoxy-Delta(9)-THC results in decreased expression of HIF1A mRNA"15313899
C0264861,2,5,6-dibenzanthracene"1,2,5,6-dibenzanthracene results in increased activity of HIF1A protein"19502547
C0264861,2,5,6-dibenzanthracene"[Benzo(a)pyrene co-treated with 1,2,5,6-dibenzanthracene] affects the expression of HIF1A mRNA"17690111
C0171391-(2-chloroethyl)-1-nitrosourea1-(2-chloroethyl)-1-nitrosourea inhibits the reaction [Acetylcysteine inhibits the reaction [Oxygen deficiency results in increased activity of HIF1A protein]]19374849
C0171391-(2-chloroethyl)-1-nitrosourea1-(2-chloroethyl)-1-nitrosourea inhibits the reaction [glutathione glycylethyl ester inhibits the reaction [Oxygen deficiency results in increased activity of HIF1A protein]]19374849
C0685431,2-diethyl-3-hydroxypyridin-4-one"1,2-diethyl-3-hydroxypyridin-4-one results in increased expression of HIF1A protein"21558026
C0685431,2-diethyl-3-hydroxypyridin-4-one"1,2-diethyl-3-hydroxypyridin-4-one results in decreased hydroxylation of HIF1A protein"21558026
C0685431,2-diethyl-3-hydroxypyridin-4-one"1,2-diethyl-3-hydroxypyridin-4-one results in increased expression of HIF1A protein"21558026
C0685431,2-diethyl-3-hydroxypyridin-4-one"1,2-diethyl-3-hydroxypyridin-4-one results in increased expression of HIF1A protein"21558026
D0140131,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt"1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt inhibits the reaction [nickel chloride results in increased expression of HIF1A protein]"22648416
C0493251,2-dithiol-3-thione"1,2-dithiol-3-thione results in decreased expression of HIF1A mRNA"19162173
C40193215,16-dihydrotanshinone I"15,16-dihydrotanshinone I inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Oxygen deficiency results in increased expression of HIF1A protein]]"26282490
C40193215,16-dihydrotanshinone I"15,16-dihydrotanshinone I inhibits the reaction [cobaltous chloride results in increased expression of HIF1A protein]"26282490
C40193215,16-dihydrotanshinone I"15,16-dihydrotanshinone I inhibits the reaction [Deferoxamine results in increased expression of HIF1A protein]"26282490
C40193215,16-dihydrotanshinone I"15,16-dihydrotanshinone I results in decreased expression of HIF1A protein"26282490
C5598531-(5-chloro-6-(trifluoromethoxy)-1H-benzoimidazol-2-yl)-1H-pyrazole-4-carboxylic acid1-(5-chloro-6-(trifluoromethoxy)-1H-benzoimidazol-2-yl)-1H-pyrazole-4-carboxylic acid results in increased expression of HIF1A protein26723917
C09724015-deoxy-delta(12,14)-prostaglandin J2"15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of HIF1A protein"17658243
C09724015-deoxy-delta(12,14)-prostaglandin J2"15-deoxy-delta(12,14)-prostaglandin J2 affects the stability of HIF1A protein"17658243
C09724015-deoxy-delta(12,14)-prostaglandin J2"15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of HIF1A protein"17658243
C09724015-deoxy-delta(12,14)-prostaglandin J2"Acetylcysteine inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of HIF1A protein]"17658243
C09724015-deoxy-delta(12,14)-prostaglandin J2"Buthionine Sulfoximine promotes the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of HIF1A protein]"17658243
C09724015-deoxy-delta(12,14)-prostaglandin J2"Dithiothreitol inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of HIF1A protein]"17658243
C09724015-deoxy-delta(12,14)-prostaglandin J2"Glutathione inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of HIF1A protein]"17658243
C44865917-(dimethylaminoethylamino)-17-demethoxygeldanamycin17-(dimethylaminoethylamino)-17-demethoxygeldanamycin inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]27899277
C0005915411-cyclopropyl-4-(4-((5-methyl-3-(3-(4-(trifluoromethoxy)phenyl)-1,2,4-oxadiazol-5-yl)-1H-pyrazol-1-yl)methyl)pyridin-2-yl)piperazine"1-cyclopropyl-4-(4-((5-methyl-3-(3-(4-(trifluoromethoxy)phenyl)-1,2,4-oxadiazol-5-yl)-1H-pyrazol-1-yl)methyl)pyridin-2-yl)piperazine inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]"24403227
C0005915411-cyclopropyl-4-(4-((5-methyl-3-(3-(4-(trifluoromethoxy)phenyl)-1,2,4-oxadiazol-5-yl)-1H-pyrazol-1-yl)methyl)pyridin-2-yl)piperazine"1-cyclopropyl-4-(4-((5-methyl-3-(3-(4-(trifluoromethoxy)phenyl)-1,2,4-oxadiazol-5-yl)-1H-pyrazol-1-yl)methyl)pyridin-2-yl)piperazine results in decreased expression of HIF1A protein"24403227
C1053511-hydroxy-2-oxo-3,3-bis(2-aminoethyl)-1-triazene"1-hydroxy-2-oxo-3,3-bis(2-aminoethyl)-1-triazene results in decreased degradation of and results in increased activity of HIF1A protein"18424783
C1053511-hydroxy-2-oxo-3,3-bis(2-aminoethyl)-1-triazene"[1-hydroxy-2-oxo-3,3-bis(2-aminoethyl)-1-triazene results in decreased degradation of HIF1A protein] which results in increased phosphorylation of and results in increased activity of TP53 protein"18424783
C1053511-hydroxy-2-oxo-3,3-bis(2-aminoethyl)-1-triazene"HIF1A protein promotes the reaction [1-hydroxy-2-oxo-3,3-bis(2-aminoethyl)-1-triazene results in increased expression of SERPINE1 protein]"18424783
C1053511-hydroxy-2-oxo-3,3-bis(2-aminoethyl)-1-triazene"U 0126 promotes the reaction [1-hydroxy-2-oxo-3,3-bis(2-aminoethyl)-1-triazene results in decreased degradation of HIF1A protein]"18424783
C0415071-methylphenanthrene[Benzo(a)pyrene co-treated with 1-methylphenanthrene] affects the expression of HIF1A mRNA17690111
C0326681-nitropyrene1-nitropyrene results in increased expression of HIF1A mRNA19041380
C5321622-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine"2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine results in decreased expression of HIF1A protein"21994956
C0297902,2',3',4,4',5-hexachlorobiphenyl"[2,4,4'-trichlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,3',4,4',5-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in increased expression of HIF1A mRNA"15808785
C1016702-(2-(4-(4-nitrobenzyloxy)phenyl)ethyl)isothiourea methanesulfonate2-(2-(4-(4-nitrobenzyloxy)phenyl)ethyl)isothiourea methanesulfonate inhibits the reaction [Digoxin affects the localization of HIF1A protein]19647009
C1016702-(2-(4-(4-nitrobenzyloxy)phenyl)ethyl)isothiourea methanesulfonate2-(2-(4-(4-nitrobenzyloxy)phenyl)ethyl)isothiourea methanesulfonate inhibits the reaction [Digoxin results in increased phosphorylation of HIF1A protein]19647009
C1016702-(2-(4-(4-nitrobenzyloxy)phenyl)ethyl)isothiourea methanesulfonate2-(2-(4-(4-nitrobenzyloxy)phenyl)ethyl)isothiourea methanesulfonate inhibits the reaction [Ouabain affects the localization of HIF1A protein]19647009
C1016702-(2-(4-(4-nitrobenzyloxy)phenyl)ethyl)isothiourea methanesulfonate2-(2-(4-(4-nitrobenzyloxy)phenyl)ethyl)isothiourea methanesulfonate inhibits the reaction [Ouabain results in increased phosphorylation of HIF1A protein]19647009
C0939732-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [cobaltous chloride results in increased activity of HIF1A protein]19808899
C0939732-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [cobaltous chloride results in increased expression of HIF1A protein]17015263
C0939732-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Deferoxamine results in increased expression of HIF1A protein]16527254
C0939732-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [FGF2 protein results in increased activity of HIF1A protein]15631803
C0939732-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [manganese chloride results in increased expression of and results in increased activity of HIF1A protein]20152896
C0939732-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Oxygen deficiency results in increased activity of HIF1A protein]19808899
C0939732-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of HIF1A protein alternative form]14695184
C0939732-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one results in decreased expression of HIF1A mRNA15169887
C0939732-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one results in decreased expression of HIF1A protein16227395
C0939732-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Deferoxamine results in increased expression of HIF1A protein]16527254
C0939732-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [PDGFB protein promotes the reaction [Nickel analog results in increased expression of HIF1A protein]]22700867
C1111182',3,3',4',5-pentachloro-4-hydroxybiphenyl"2',3,3',4',5-pentachloro-4-hydroxybiphenyl results in decreased expression of HIF1A mRNA"19114083
C0700552,3',4,4',5-pentachlorobiphenyl"[2,4,4'-trichlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,3',4,4',5-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in increased expression of HIF1A mRNA"15808785
C0388902,3,4,7,8-pentachlorodibenzofuran"2,3,4,7,8-pentachlorodibenzofuran results in decreased expression of HIF1A mRNA"21724226
C0142112,3,7,8-tetrachlorodibenzofuran"2,3,7,8-tetrachlorodibenzofuran affects the expression of HIF1A mRNA"18343893
C0630022,3-dimethoxy-1,4-naphthoquinone"2,3-dimethoxy-1,4-naphthoquinone inhibits the reaction [S-Nitrosoglutathione results in increased expression of HIF1A protein]"11514583
C0630022,3-dimethoxy-1,4-naphthoquinone"2,3-dimethoxy-1,4-naphthoquinone inhibits the reaction [TNF protein results in increased expression of HIF1A protein]"11514583
C5736932-(4-((4-(6-methoxy-3-pyridinyl)-5-(4-(trifluoromethoxy)phenyl)-2-thiazolyl)methoxy)-2-methylphenoxy)acetic acid2-(4-((4-(6-methoxy-3-pyridinyl)-5-(4-(trifluoromethoxy)phenyl)-2-thiazolyl)methoxy)-2-methylphenoxy)acetic acid results in decreased expression of HIF1A mRNA22193206
C0817662,4,4'-trichlorobiphenyl"[2,4,4'-trichlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,3',4,4',5-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in increased expression of HIF1A mRNA"15808785
C0140242,4,5,2',4',5'-hexachlorobiphenyl"[2,4,4'-trichlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,3',4,4',5-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in increased expression of HIF1A mRNA"15808785
C0098282,4,5,2',5'-pentachlorobiphenyl"[2,4,4'-trichlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,3',4,4',5-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in increased expression of HIF1A mRNA"15808785
C0859112-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [4-hydroxyestradiol results in increased expression of HIF1A protein]15050414
C0859112-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Cadmium Chloride results in increased expression of HIF1A protein]21984483
C0859112-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [cobaltous chloride results in increased activity of HIF1A protein]17082639|1980889
C0859112-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [cobaltous chloride results in increased expression of HIF1A protein]17015263|1708263
C0859112-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [FGF2 protein results in increased expression of and results in increased activity of HIF1A protein]15631803
C0859112-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [IGF1 protein results in increased expression of HIF1A protein]16682453
C0859112-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A mRNA]11424089|1892413
C0859112-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]17307335|1980889
C0859112-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [sodium arsenite results in increased expression of HIF1A protein]23968725
C0859112-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in decreased activity of HIF1A protein15631803
C0859112-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in decreased expression of HIF1A protein14726529|1521331
C07699627-hydroxycholesterol27-hydroxycholesterol results in increased expression of HIF1A protein27856279
C0495842-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine"2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of HIF1A protein"22307971
C5706622-amino-8-(4-(2-hydroxyethoxy)cyclohexyl)-6-(6-methoxypyridin-3-yl)-4-methylpyrido(2,3-d)pyrimidin-7(8H)-one"2-amino-8-(4-(2-hydroxyethoxy)cyclohexyl)-6-(6-methoxypyridin-3-yl)-4-methylpyrido(2,3-d)pyrimidin-7(8H)-one results in decreased expression of HIF1A protein"23639247
C0065932-anthramine2-anthramine results in increased activity of HIF1A protein19502547
C0069952-chloroethyl isocyanate[cobaltous chloride results in increased activity of HIF1A protein] which results in decreased susceptibility to 2-chloroethyl isocyanate14980978
C0228302-methoxyestradiol2-methoxyestradiol inhibits the reaction [Glucose results in increased expression of HIF1A protein]21617913
C0415253,3',4,5'-tetrahydroxystilbene"[3,3',4,5'-tetrahydroxystilbene results in increased activity of SIRT1 protein] which results in increased expression of HIF1A protein"22245592
C0415253,3',4,5'-tetrahydroxystilbene"3,3',4,5'-tetrahydroxystilbene results in increased expression of HIF1A protein"22245592
C0284513,4,3',4'-tetrachlorobiphenyl"[3,4,3',4'-tetrachlorobiphenyl co-treated with 3,4,5,3',4'-pentachlorobiphenyl co-treated with 3,4,5,3',4',5'-hexachlorobiphenyl] results in decreased expression of HIF1A mRNA"15808785
C0273093,4,5,3',4',5'-hexachlorobiphenyl"[3,4,3',4'-tetrachlorobiphenyl co-treated with 3,4,5,3',4'-pentachlorobiphenyl co-treated with 3,4,5,3',4',5'-hexachlorobiphenyl] results in decreased expression of HIF1A mRNA"15808785
C0230353,4,5,3',4'-pentachlorobiphenyl"3,4,5,3',4'-pentachlorobiphenyl affects the localization of HIF1A protein"24916446
C0230353,4,5,3',4'-pentachlorobiphenyl"[3,4,3',4'-tetrachlorobiphenyl co-treated with 3,4,5,3',4'-pentachlorobiphenyl co-treated with 3,4,5,3',4',5'-hexachlorobiphenyl] results in decreased expression of HIF1A mRNA"15808785
C0230353,4,5,3',4'-pentachlorobiphenyl"3,4,5,3',4'-pentachlorobiphenyl affects the localization of HIF1A protein"24916446
C5287403-(4-bromophenyl)-2-(ethylsulfonyl)-6-methylquinoxaline-1,4-dioxide"3-(4-bromophenyl)-2-(ethylsulfonyl)-6-methylquinoxaline-1,4-dioxide inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Oxygen deficiency results in increased expression of HIF1A protein]]"20524035
C5287403-(4-bromophenyl)-2-(ethylsulfonyl)-6-methylquinoxaline-1,4-dioxide"3-(4-bromophenyl)-2-(ethylsulfonyl)-6-methylquinoxaline-1,4-dioxide inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]"20524035
C5202903,4-dihydroxybenzoate"[3,4-dihydroxybenzoate co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in increased expression of HIF1A mRNA"19679656
C5202903,4-dihydroxybenzoate"3,4-dihydroxybenzoate results in increased expression of HIF1A mRNA"19679656
C5202903,4-dihydroxybenzoate"3,4-dihydroxybenzoate affects the localization of HIF1A protein"19679656
C5202903,4-dihydroxybenzoate"[3,4-dihydroxybenzoate co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine metabolite] affects the localization of HIF1A protein"19679656
C5758943,4-dimethoxy-N-((2,2-dimethyl-2H-chromen-6-yl)methyl)-N-phenylbenzenesulfonamide"3,4-dimethoxy-N-((2,2-dimethyl-2H-chromen-6-yl)methyl)-N-phenylbenzenesulfonamide inhibits the reaction [[HIF1A protein binds to ARNT protein] binds to [EP300 protein binds to CREBBP protein]]"22032632
C5240423,5-bis(2-fluorobenzylidene)piperidin-4-one"3,5-bis(2-fluorobenzylidene)piperidin-4-one results in decreased expression of and results in decreased activity of HIF1A protein"18682687
C5240423,5-bis(2-fluorobenzylidene)piperidin-4-one"VHL protein promotes the reaction [3,5-bis(2-fluorobenzylidene)piperidin-4-one results in decreased expression of HIF1A protein]"18682687
C4390243,5-dihydroxy-4'-methoxystilbene"3,5-dihydroxy-4'-methoxystilbene inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]"24975222
C0909373-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole inhibits the reaction [Cobalt results in increased expression of HIF1A protein]11286986
C0909373-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole inhibits the reaction [Deferoxamine results in increased expression of HIF1A protein]11286986
C0909373-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole inhibits the reaction [Digoxin affects the localization of HIF1A protein]19647009
C0909373-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole inhibits the reaction [HIF1A protein promotes the reaction [Oxygen deficiency results in increased expression of CD36 mRNA]]19640849
C0909373-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole inhibits the reaction [HIF1A protein promotes the reaction [Oxygen deficiency results in increased expression of CD36 protein]]19640849
C0909373-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole inhibits the reaction [Ouabain affects the localization of HIF1A protein]19647009
C0909373-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]11286986
C0909373-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole results in decreased activity of HIF1A protein19640849|2427097
C0909373-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole inhibits the reaction [cobaltous chloride results in decreased expression of HIF1A protein]24265542
C0909373-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole inhibits the reaction [cobaltous chloride results in increased expression of HIF1A protein]24265542
C0909373-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole inhibits the reaction [Glucose results in increased expression of HIF1A protein]21617913
C0909373-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole[3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole results in decreased activity of HIF1A protein] results in decreased susceptibility to [Oxygen deficiency co-treated with Glucose deficiency]23108914
C0909373-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole results in increased expression of HIF1A mRNA24265542
C0909373-(5'-hydroxymethyl-2'-furyl)-1-benzylindazolecobaltous chloride inhibits the reaction [3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole results in increased expression of HIF1A mRNA]24265542
C0909373-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole results in decreased activity of HIF1A protein23108914
C5542893-hydroxylup-20(29)-ene-27,28-dioic acid dimethyl ester"3-hydroxylup-20(29)-ene-27,28-dioic acid dimethyl ester results in decreased expression of HIF1A protein"20670616
C0259463-methyladenine3-methyladenine inhibits the reaction [CR 3294 results in decreased expression of HIF1A protein]18927491
C0909424-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [Potassium Dichromate results in increased expression of HIF1A protein]12213806
C0909424-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [sodium arsenite results in increased expression of HIF1A protein]12482858
C5688624-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline"4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline inhibits the reaction [bisphenol A results in increased expression of HIF1A protein]"28964603
C1081234-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine"4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]"15913578
C0140364-hydroxyestradiol2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [4-hydroxyestradiol results in increased expression of HIF1A protein]15050414
C0140364-hydroxyestradiol4-hydroxyestradiol results in increased expression of HIF1A protein15050414
C0140364-hydroxyestradiolSirolimus inhibits the reaction [4-hydroxyestradiol results in increased expression of HIF1A protein]15050414
C0140364-hydroxyestradiolwortmannin inhibits the reaction [4-hydroxyestradiol results in increased expression of HIF1A protein]15050414
C0021664-methyl-7-diethylaminocoumarin4-methyl-7-diethylaminocoumarin results in increased activity of HIF1A protein19502547
C5075534'-O-methylalpinumisoflavone"4'-O-methylalpinumisoflavone inhibits the reaction [1,10-phenanthroline deficiency results in increased activity of HIF1A protein]"19091749
C5075534'-O-methylalpinumisoflavone4'-O-methylalpinumisoflavone inhibits the reaction [Oxygen deficiency results in increased activity of HIF1A protein]19091749
C5075534'-O-methylalpinumisoflavone4'-O-methylalpinumisoflavone inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]19091749
C0297284-phenylenediamine4-phenylenediamine results in increased expression of HIF1A mRNA16314067
C0126064-vinyl-1-cyclohexene dioxide4-vinyl-1-cyclohexene dioxide affects the expression of HIF1A mRNA20829426
C0587225-hydroxy-6,8,11,14,17-eicosapentaenoic acid"5-hydroxy-6,8,11,14,17-eicosapentaenoic acid affects the expression of HIF1A mRNA"26984781
C000601052(6,7-dimethoxyquinolin-4-yl)(5-methoxy-2,2-dimethyl-2H-chromen-6-yl)methyl acetate"(6,7-dimethoxyquinolin-4-yl)(5-methoxy-2,2-dimethyl-2H-chromen-6-yl)methyl acetate results in decreased expression of HIF1A protein"25976766
C0106436-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid"6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [Cadmium inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]]"10866824
C0106436-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid"6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [cobaltous chloride results in increased expression of HIF1A protein]"17015263
C1217077,3'-dihydroxy-4'-methoxyisoflavone"7,3'-dihydroxy-4'-methoxyisoflavone results in increased expression of and results in decreased degradation of HIF1A protein"21309574
C1217077,3'-dihydroxy-4'-methoxyisoflavone"7,3'-dihydroxy-4'-methoxyisoflavone results in increased expression of HIF1A mRNA"21309574
D000082AcetaminophenAcetaminophen affects the expression of HIF1A mRNA17562736
D000082AcetaminophenAcetaminophen results in increased expression of HIF1A protein16530163|2012375
D000082AcetaminophenAcetylcysteine inhibits the reaction [Acetaminophen results in increased expression of HIF1A protein]16530163
D000082AcetaminophenCyclosporine inhibits the reaction [Acetaminophen results in increased expression of HIF1A]21316383
D000082AcetaminophenCyclosporine inhibits the reaction [Acetaminophen results in increased expression of HIF1A protein]16530163
C056165acetovanilloneacetovanillone inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]23144690
C056165acetovanilloneacetovanillone results in increased expression of HIF1A protein12595275
D000111Acetylcysteine1-(2-chloroethyl)-1-nitrosourea inhibits the reaction [Acetylcysteine inhibits the reaction [Oxygen deficiency results in increased activity of HIF1A protein]]19374849
D000111Acetylcysteine"Acetylcysteine inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of HIF1A protein]"17658243
D000111AcetylcysteineAcetylcysteine inhibits the reaction [Cadmium inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]]10866824
D000111AcetylcysteineAcetylcysteine inhibits the reaction [Cisplatin affects the localization of HIF1A protein]17066447
D000111AcetylcysteineAcetylcysteine inhibits the reaction [cobaltous chloride results in increased expression of HIF1A protein]11886167|1367921
D000111AcetylcysteineAcetylcysteine inhibits the reaction [Dopamine results in increased expression of HIF1A protein]19410601
D000111AcetylcysteineAcetylcysteine inhibits the reaction [Fluorouracil affects the localization of HIF1A protein]17066447
D000111AcetylcysteineAcetylcysteine inhibits the reaction [nickel chloride results in increased expression of HIF1A protein]22648416
D000111AcetylcysteineAcetylcysteine inhibits the reaction [Oxygen deficiency results in increased activity of HIF1A protein]19374849
D000111AcetylcysteineAcetylcysteine inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A mRNA]19374849
D000111AcetylcysteineAcetylcysteine inhibits the reaction [sodium arsenite results in increased expression of HIF1A protein]11641398
D000111AcetylcysteineAcetylcysteine inhibits the reaction [titanium dioxide results in increased expression of HIF1A protein]25406100
D000111Acetylcysteineebselen inhibits the reaction [Acetylcysteine inhibits the reaction [Oxygen deficiency results in increased activity of HIF1A protein]]19374849
D000111Acetylcysteineebselen inhibits the reaction [Acetylcysteine inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A mRNA]]19374849
D000111AcetylcysteineAcetylcysteine inhibits the reaction [Acetaminophen results in increased expression of HIF1A protein]16530163
D000111AcetylcysteineAcetylcysteine inhibits the reaction [titanium dioxide results in increased expression of HIF1A protein]25406100
D000111AcetylcysteineAcetylcysteine inhibits the reaction [Nickel analog results in increased expression of HIF1A protein]22700867
D000111AcetylcysteineAcetylcysteine inhibits the reaction [PDGFB protein promotes the reaction [Nickel analog results in increased expression of HIF1A protein]]22700867
D000241AdenosineAdenosine results in increased expression of HIF1A mRNA20067761
D000255Adenosine TriphosphateAdenosine Triphosphate inhibits the reaction [protoporphyrin IX results in decreased activity of HIF1A protein]23624237
D016604Aflatoxin B1Aflatoxin B1 affects the expression of HIF1A protein20106945
D016604Aflatoxin B1Aflatoxin B1 results in increased expression of HIF1A mRNA27153756
C412373AG 1879AG 1879 inhibits the reaction [[cobaltous chloride results in increased activity of SRC protein] which results in increased expression of HIF1A protein]15735682
C412373AG 1879AG 1879 inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]15913578
C029743alpha-ketoglutaric acid[benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with alpha-ketoglutaric acid co-treated with Ascorbic Acid co-treated with ferrous chloride] promotes the reaction [VHL protein binds to HIF1A protein]19263519
C029743alpha-ketoglutaric acidmanganese chloride inhibits the reaction [[benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with alpha-ketoglutaric acid co-treated with Ascorbic Acid co-treated with ferrous chloride] promotes the reaction [VHL protein binds to HIF1A protein]]19263519
C029743alpha-ketoglutaric acidalpha-ketoglutaric acid results in increased hydroxylation of and results in increased degradation of HIF1A protein24128854
C029743alpha-ketoglutaric acid[alpha-ketoglutaric acid results in increased hydroxylation of and results in increased degradation of HIF1A protein] which results in decreased expression of VEGFA24128854
C000154alpinumisoflavone"alpinumisoflavone inhibits the reaction [1,10-phenanthroline deficiency results in increased activity of HIF1A protein]"19091749
C000154alpinumisoflavonealpinumisoflavone inhibits the reaction [Oxygen deficiency results in increased activity of HIF1A protein]19091749
D000535AluminumAluminum results in increased localization of HIF1A protein16979867
D000596Amino AcidsAmino Acids inhibits the reaction [cobaltous chloride results in increased expression of HIF1A protein]21036805
D000585AminacrineAminacrine results in increased activity of HIF1A protein19502547
D000643Ammonium ChlorideAmmonium Chloride affects the expression of HIF1A mRNA16483693
D000666Amphotericin BAmphotericin B inhibits the reaction [[HIF1A protein binds to ARNT protein] which binds to EPO enhancer]16189267
D000666Amphotericin BAmphotericin B inhibits the reaction [Oxygen deficiency promotes the reaction [HIF1A protein binds to EP300 protein]]16189267
D000666Amphotericin BAmphotericin B promotes the reaction [HIF1AN protein binds to and results in increased hydroxylation of and results in decreased activity of HIF1A protein]16189267
D000666Amphotericin BAmphotericin B results in decreased activity of HIF1A protein16189267
C553921amurensin G[amurensin G results in decreased activity of SIRT1 protein] inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]22245592
C030419andrographolide[andrographolide co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] results in increased ubiquitination of HIF1A protein28651835
C030419andrographolide[andrographolide co-treated with cobaltous chloride] results in increased hydroxylation of HIF1A protein27297870
C030419andrographolideandrographolide inhibits the reaction [cobaltous chloride results in increased expression of HIF1A mRNA]27297870
C030419andrographolideandrographolide inhibits the reaction [HIF1A protein binds to VEGFA promoter]21134392
C030419andrographolideandrographolide results in decreased expression of and affects the localization of HIF1A protein28651835
C030419andrographolideandrographolide results in decreased expression of and results in increased degradation of HIF1A protein21134392
C030419andrographolideandrographolide results in decreased expression of HIF1A protein28651835
C030419andrographolideandrographolide results in increased expression of HIF1A protein modified form21134392
C030419andrographolidebenzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [andrographolide results in decreased expression of HIF1A protein]28651835
C030419andrographolidebenzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [andrographolide results in increased degradation of HIF1A protein]21134392
C030419andrographolideEGLN1 mutant form inhibits the reaction [andrographolide results in decreased expression of HIF1A protein]21134392
C030419andrographolideHMOX1 protein affects the reaction [andrographolide inhibits the reaction [cobaltous chloride results in increased expression of HIF1A mRNA]]27297870
C030419andrographolideNFE2L2 protein affects the reaction [andrographolide inhibits the reaction [cobaltous chloride results in increased expression of HIF1A mRNA]]27297870
C030419andrographolidepyrazolanthrone inhibits the reaction [andrographolide results in decreased expression of HIF1A protein]28651835
C053442annonacinannonacin inhibits the reaction [Oxygen deficiency results in increased expression of and affects the localization of HIF1A protein]20423107
D000968Antimycin AAntimycin A affects the expression of HIF1A protein16034640
D018501Antirheumatic AgentsAntirheumatic Agents results in decreased expression of HIF1A mRNA24449571
D047310ApigeninApigenin inhibits the reaction [Oxygen deficiency promotes the reaction [HIF1A protein binds to EP300 protein]]20153296
D047310ApigeninApigenin inhibits the reaction [Oxygen deficiency results in increased activity of HIF1A protein]19958256
D047310ApigeninApigenin results in decreased activity of HIF1A protein19958256
D047310ApigeninApigenin results in decreased expression of HIF1A protein15947208
D047310ApigeninApigenin results in decreased expression of HIF1A23743303
C000228aristolochic acid Iaristolochic acid I affects the localization of HIF1A protein21554934
D001151Arsenic[Arsenic results in increased abundance of Reactive Oxygen Species] which results in increased expression of HIF1A protein21687637
D001151Arsenic[[Arsenic results in increased abundance of Reactive Oxygen Species] which results in increased expression of HIF1A protein] which results in increased expression of VEGFA mRNA21687637
D001151ArsenicCAT protein inhibits the reaction [[Arsenic results in increased abundance of Reactive Oxygen Species] which results in increased expression of HIF1A protein]21687637
D001151ArsenicCAT protein inhibits the reaction [[[Arsenic results in increased abundance of Reactive Oxygen Species] which results in increased expression of HIF1A protein] which results in increased expression of VEGFA mRNA]21687637
D001151Arsenicdiphenyleneiodonium inhibits the reaction [[Arsenic results in increased abundance of Reactive Oxygen Species] which results in increased expression of HIF1A protein]21687637
D001151Arsenicdiphenyleneiodonium inhibits the reaction [[[Arsenic results in increased abundance of Reactive Oxygen Species] which results in increased expression of HIF1A protein] which results in increased expression of VEGFA mRNA]21687637
D001151Arsenic[Nickel co-treated with Arsenic] results in increased expression of HIF1A protein16386771
C006632arsenic trioxidearsenic trioxide affects the expression of HIF1A mRNA20458559
C006632arsenic trioxidearsenic trioxide promotes the reaction [cobaltous chloride results in increased expression of HIF1A protein]16330433
C006632arsenic trioxidearsenic trioxide promotes the reaction [Deferoxamine results in increased expression of HIF1A protein]16330433
C006632arsenic trioxidearsenic trioxide results in decreased expression of HIF1A25088040
C006632arsenic trioxidearsenic trioxide results in decreased expression of HIF1A mRNA19769630
C006632arsenic trioxidearsenic trioxide results in decreased expression of HIF1A protein25047463
C006632arsenic trioxidearsenic trioxide results in increased expression of HIF1A protein12482858
C006632arsenic trioxide[Oxygen deficiency co-treated with arsenic trioxide] results in increased expression of HIF1A protein19825857
C006632arsenic trioxidearsenic trioxide results in increased expression of HIF1A protein15888669
C015001arsenitearsenite results in increased expression of HIF1A protein14604972|1497164
C015001arsenitearsenite affects the localization of HIF1A protein20835880
C015001arsenitearsenite promotes the reaction [PIK3R1 protein results in increased expression of HIF1A mRNA]20835880
C015001arsenitearsenite promotes the reaction [PIK3R1 protein results in increased expression of HIF1A protein]20835880
C015001arsenitearsenite results in increased expression of HIF1A mRNA15868481
C015001arsenitearsenite results in increased expression of HIF1A protein20835880
C015001arsenitePIK3R1 gene mutant form inhibits the reaction [arsenite results in increased expression of HIF1A protein]20835880
D017638Asbestos, Crocidolite"Asbestos, Crocidolite results in increased activity of HIF1A protein"18385176
D017638Asbestos, Crocidolite"ferric nitrilotriacetate inhibits the reaction [Asbestos, Crocidolite results in increased activity of HIF1A protein]"18385176
D001205Ascorbic AcidAscorbic Acid inhibits the reaction [chromium hexavalent ion results in increased stability of HIF1A protein]17382205
D001205Ascorbic AcidAscorbic Acid inhibits the reaction [cupric chloride results in decreased hydroxylation of HIF1A protein]19074761
D001205Ascorbic AcidAscorbic Acid inhibits the reaction [cupric chloride results in increased stability of HIF1A protein]19074761
D001205Ascorbic AcidAscorbic Acid inhibits the reaction [manganese chloride results in decreased hydroxylation of HIF1A protein]19074761
D001205Ascorbic AcidAscorbic Acid inhibits the reaction [manganese chloride results in increased stability of HIF1A protein]19074761
D001205Ascorbic AcidAscorbic Acid inhibits the reaction [nickel sulfate results in decreased hydroxylation of HIF1A protein]19074761
D001205Ascorbic AcidAscorbic Acid inhibits the reaction [nickel sulfate results in increased expression of HIF1A protein]16288478
D001205Ascorbic AcidAscorbic Acid inhibits the reaction [nickel sulfate results in increased stability of HIF1A protein]17382205
D001205Ascorbic AcidAscorbic Acid inhibits the reaction [potassium chromate(VI) results in increased stability of HIF1A protein]17382205
D001205Ascorbic AcidAscorbic Acid inhibits the reaction [Quercetin results in increased expression of HIF1A protein]17364964
D001205Ascorbic AcidAscorbic Acid inhibits the reaction [sodium arsenite results in decreased hydroxylation of HIF1A protein]19074761
D001205Ascorbic AcidAscorbic Acid inhibits the reaction [sodium arsenite results in increased expression of HIF1A protein]24188932
D001205Ascorbic AcidAscorbic Acid inhibits the reaction [sodium arsenite results in increased stability of HIF1A protein]19074761|2418893
D001205Ascorbic AcidAscorbic Acid inhibits the reaction [Vanadates results in decreased hydroxylation of HIF1A protein]19074761
D001205Ascorbic AcidAscorbic Acid inhibits the reaction [Vanadates results in increased stability of HIF1A protein]19074761
D001205Ascorbic AcidAscorbic Acid results in increased degradation of HIF1A protein19074761
D001205Ascorbic Acid[benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with alpha-ketoglutaric acid co-treated with Ascorbic Acid co-treated with ferrous chloride] promotes the reaction [VHL protein binds to HIF1A protein]19263519
D001205Ascorbic Acidmanganese chloride inhibits the reaction [[benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with alpha-ketoglutaric acid co-treated with Ascorbic Acid co-treated with ferrous chloride] promotes the reaction [VHL protein binds to HIF1A protein]]19263519
D001205Ascorbic AcidAscorbic Acid inhibits the reaction [AGT protein modified form results in decreased hydroxylation of HIF1A protein]20881940
D001205Ascorbic AcidAscorbic Acid inhibits the reaction [Hydrogen Peroxide results in decreased hydroxylation of HIF1A protein]20881940
D001280AtrazineAtrazine results in increased expression of HIF1A mRNA22982499
C406592azaspiracidazaspiracid results in decreased expression of HIF1A mRNA28939011
C547126AZM551248AZM551248 results in increased expression of HIF1A mRNA22323515
C040929bafilomycin A1bafilomycin A1 results in increased expression of HIF1A protein25981168
C040929bafilomycin A1HIF1A mutant form inhibits the reaction [bafilomycin A1 results in increased expression of BNIP3 mRNA]25981168
C040929bafilomycin A1HIF1A mutant form promotes the reaction [bafilomycin A1 results in increased cleavage of PARP1 protein]25981168
C040929bafilomycin A1lapatinib inhibits the reaction [bafilomycin A1 results in increased expression of HIF1A protein]25981168
C013830baysilon[baysilon results in increased abundance of Oxygen] which results in decreased expression of HIF1A mRNA29156398
C013830baysilon[baysilon results in increased abundance of Oxygen] which results in decreased expression of HIF1A protein29156398
C006703benzo(b)fluoranthene[Benzo(a)pyrene co-treated with benzo(b)fluoranthene] affects the expression of HIF1A mRNA17690111
C006703benzo(b)fluoranthenebenzo(b)fluoranthene results in increased activity of HIF1A protein19502547
C022921benzo(k)fluoranthenebenzo(k)fluoranthene results in increased activity of HIF1A protein19502547
C022921benzo(k)fluoranthenebenzo(k)fluoranthene promotes the reaction [Oxygen deficiency results in increased activity of HIF1A protein]19539049
D001564Benzo(a)pyreneBenzo(a)pyrene affects the activity of HIF1A protein20624995
D001564Benzo(a)pyrene"[Benzo(a)pyrene co-treated with 1,2,5,6-dibenzanthracene] affects the expression of HIF1A mRNA"17690111
D001564Benzo(a)pyrene[Benzo(a)pyrene co-treated with 1-methylphenanthrene] affects the expression of HIF1A mRNA17690111
D001564Benzo(a)pyrene[Benzo(a)pyrene co-treated with benzo(b)fluoranthene] affects the expression of HIF1A mRNA17690111
D001564Benzo(a)pyrene"[Benzo(a)pyrene co-treated with dibenzo(a,l)pyrene] affects the expression of HIF1A mRNA"17690111
D001564Benzo(a)pyrene[Benzo(a)pyrene co-treated with fluoranthene] affects the expression of HIF1A mRNA17690111
D001564Benzo(a)pyreneBenzo(a)pyrene inhibits the reaction [cobaltous chloride affects the localization of HIF1A protein]26350169
D001564Benzo(a)pyreneBenzo(a)pyrene inhibits the reaction [cobaltous chloride promotes the reaction [HIF1A protein binds to ARNT protein]]20228066
D001564Benzo(a)pyreneBenzo(a)pyrene affects the expression of HIF1A mRNA22342234
D001564Benzo(a)pyreneBenzo(a)pyrene inhibits the reaction [Oxygen deficiency results in increased activity of HIF1A protein]19539049
D001564Benzo(a)pyreneBenzo(a)pyrene results in decreased activity of HIF1A protein19539049
D001564Benzo(a)pyreneBenzo(a)pyrene results in decreased expression of HIF1A protein21467743
C072553benzyloxycarbonylleucyl-leucyl-leucine aldehydebenzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased degradation of and results in increased expression of HIF1A protein15878343
C072553benzyloxycarbonylleucyl-leucyl-leucine aldehyde"15,16-dihydrotanshinone I inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Oxygen deficiency results in increased expression of HIF1A protein]]"26282490
C072553benzyloxycarbonylleucyl-leucyl-leucine aldehyde"3-(4-bromophenyl)-2-(ethylsulfonyl)-6-methylquinoxaline-1,4-dioxide inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Oxygen deficiency results in increased expression of HIF1A protein]]"20524035
C072553benzyloxycarbonylleucyl-leucyl-leucine aldehyde[andrographolide co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] results in increased ubiquitination of HIF1A protein28651835
C072553benzyloxycarbonylleucyl-leucyl-leucine aldehyde[benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with alpha-ketoglutaric acid co-treated with Ascorbic Acid co-treated with ferrous chloride] promotes the reaction [VHL protein binds to HIF1A protein]19263519
C072553benzyloxycarbonylleucyl-leucyl-leucine aldehydebenzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [andrographolide results in decreased expression of HIF1A protein]28651835
C072553benzyloxycarbonylleucyl-leucyl-leucine aldehydebenzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [andrographolide results in increased degradation of HIF1A protein]21134392
C072553benzyloxycarbonylleucyl-leucyl-leucine aldehydebenzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [deguelin results in increased degradation of HIF1A protein]17764071
C072553benzyloxycarbonylleucyl-leucyl-leucine aldehydebenzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [geldanamycin results in increased degradation of HIF1A protein]11980636
C072553benzyloxycarbonylleucyl-leucyl-leucine aldehydebenzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [L-4F peptide inhibits the reaction [INS protein results in increased expression of HIF1A protein]]22537771
C072553benzyloxycarbonylleucyl-leucyl-leucine aldehydebenzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [MALAT1 mRNA affects the reaction [sodium arsenite results in increased expression of HIF1A protein]]27287256
C072553benzyloxycarbonylleucyl-leucyl-leucine aldehydebenzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [resveratrol inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]]24975222
C072553benzyloxycarbonylleucyl-leucyl-leucine aldehydebenzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [scutellarin inhibits the reaction [[cobaltous chloride co-treated with Glucose] results in increased expression of HIF1A protein]]25192544
C072553benzyloxycarbonylleucyl-leucyl-leucine aldehydebenzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [scutellarin results in decreased expression of HIF1A protein]25192544
C072553benzyloxycarbonylleucyl-leucyl-leucine aldehydebenzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [[Dinoprostone binds to and results in increased activity of PTGER1 protein] which results in increased expression of HIF1A protein]20335389
C072553benzyloxycarbonylleucyl-leucyl-leucine aldehydebenzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [HIF1A protein binds to VHL protein]17973296
C072553benzyloxycarbonylleucyl-leucyl-leucine aldehydebenzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Oxygen deficiency results in increased expression of HIF1A protein]20524035|2055453
C072553benzyloxycarbonylleucyl-leucyl-leucine aldehydebenzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [VHL protein binds to HIF1A protein]19263519
C072553benzyloxycarbonylleucyl-leucyl-leucine aldehydebenzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased degradation of and results in increased expression of HIF1A protein18682687
C072553benzyloxycarbonylleucyl-leucyl-leucine aldehydebenzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased degradation of HIF1A protein17764071
C072553benzyloxycarbonylleucyl-leucyl-leucine aldehydebenzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of HIF1A protein19254699|2449796
C072553benzyloxycarbonylleucyl-leucyl-leucine aldehydebenzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of HIF1A protein modified form17973296|2055453
C072553benzyloxycarbonylleucyl-leucyl-leucine aldehydeCurcumin analog inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Oxygen deficiency results in increased expression of HIF1A protein]]20554536
C072553benzyloxycarbonylleucyl-leucyl-leucine aldehydeCurcumin analog inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of HIF1A protein modified form]20554536
C072553benzyloxycarbonylleucyl-leucyl-leucine aldehydeGlucosamine affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of HIF1A protein]19254699
C072553benzyloxycarbonylleucyl-leucyl-leucine aldehydemanganese chloride inhibits the reaction [[benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with alpha-ketoglutaric acid co-treated with Ascorbic Acid co-treated with ferrous chloride] promotes the reaction [VHL protein binds to HIF1A protein]]19263519
C072553benzyloxycarbonylleucyl-leucyl-leucine aldehydeQuercetin inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [HIF1A protein binds to VHL protein]]17973296
C072553benzyloxycarbonylleucyl-leucyl-leucine aldehyderesveratrol inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Oxygen deficiency results in increased expression of HIF1A protein]]24975222
C072553benzyloxycarbonylleucyl-leucyl-leucine aldehydebenzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [resveratrol results in decreased expression of HIF1A protein]24221993
C072553benzyloxycarbonylleucyl-leucyl-leucine aldehydebenzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of HIF1A protein23593480
C072553benzyloxycarbonylleucyl-leucyl-leucine aldehydeCycloheximide inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of HIF1A protein]23593480
C072553benzyloxycarbonylleucyl-leucyl-leucine aldehydebenzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased degradation of HIF1A protein20335389
C038328BEP protocolBEP protocol results in increased expression of HIF1A mRNA18987330
D004958EstradiolEstradiol inhibits the reaction [Progesterone results in increased expression of HIF1A mRNA]17275223
D004958EstradiolEstradiol promotes the reaction [[HIF1A protein binds to VEGFA promoter] which results in increased expression of VEGFA mRNA]15774498
D004958EstradiolEstradiol results in increased expression of HIF1A mRNA15774498
D004958EstradiolEstradiol results in increased expression of HIF1A protein15774498
C002503betulinbetulin analog inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]26540049
C002503betulinbetulin analog results in decreased expression of HIF1A protein26540049
C002070betulinic acidbetulinic acid results in decreased expression of HIF1A protein26540049
D001663BilirubinBilirubin inhibits the reaction [cobaltous chloride results in increased expression of HIF1A mRNA]27297870
D001663BilirubinBilirubin inhibits the reaction [cobaltous chloride results in increased expression of HIF1A protein]27297870
D0150822,2'-Dipyridyl"2,2'-Dipyridyl results in increased expression of HIF1A protein"18674879
D0150822,2'-Dipyridyl"resveratrol inhibits the reaction [2,2'-Dipyridyl results in increased expression of HIF1A protein]"18674879
C070515bisindolylmaleimide Ibisindolylmaleimide I inhibits the reaction [sodium arsenite results in increased expression of HIF1A mRNA]15089098
C006780bisphenol A"4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline inhibits the reaction [bisphenol A results in increased expression of HIF1A protein]"28964603
C006780bisphenol Abisphenol A inhibits the reaction [Cobalt results in decreased ubiquitination of and results in decreased degradation of HIF1A protein]15147973
C006780bisphenol Abisphenol A inhibits the reaction [HIF1A protein results in increased expression of EPO mRNA]15147973
C006780bisphenol Abisphenol A results in decreased expression of HIF1A mRNA25047013
C006780bisphenol Abisphenol A results in increased degradation of HIF1A protein15147973
C006780bisphenol Abisphenol A results in increased expression of HIF1A protein28964603
C006780bisphenol Abisphenol A affects the methylation of HIF1A promoter27334623
C006780bisphenol Abisphenol A analog results in decreased activity of HIF1A protein20432243
C006780bisphenol Abisphenol A affects the expression of HIF1A mRNA25181051
C006780bisphenol Abisphenol A results in increased expression of HIF1A mRNA28721559
D001761BleomycinBleomycin results in increased expression of HIF1A mRNA28434932
D001761BleomycinDinoprostone inhibits the reaction [Bleomycin results in increased expression of HIF1A mRNA]28434932
D001761BleomycinHIF1A protein affects the reaction [Dinoprostone inhibits the reaction [Bleomycin results in increased expression of TGFB3 mRNA]]28434932
D001761Bleomycin[HIF1A protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of CTGF mRNA]28434932
D001761Bleomycin[HIF1A protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFB1 mRNA]28434932
D001761Bleomycin[HIF1A protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFB2 mRNA]28434932
D001761Bleomycin[HIF1A protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFBR1 mRNA]28434932
D001761Bleomycin[HIF1A protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFBR2 mRNA]28434932
D000069286BortezomibBortezomib results in increased expression of HIF1A protein16061869
D000069286BortezomibBortezomib promotes the reaction [HIF1AN protein binds to HIF1A protein]18174379
D000069286BortezomibBortezomib results in decreased activity of HIF1A protein18174379
C032036bromobenzene[bromobenzene co-treated with EGLN1 mutant form] results in increased expression of HIF1A protein24190904
C017092bromopyruvatebromopyruvate results in decreased expression of HIF1A28433571
D019328Buthionine Sulfoximine"Buthionine Sulfoximine promotes the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of HIF1A protein]"17658243
D019328Buthionine SulfoximineButhionine Sulfoximine promotes the reaction [sodium arsenite results in increased expression of HIF1A protein]11641398
D019328Buthionine SulfoximineButhionine Sulfoximine results in increased activity of HIF1A protein11841787
D020122tert-Butylhydroperoxide[HIF1A protein results in increased expression of MCL1 protein] which results in decreased susceptibility to tert-Butylhydroperoxide15611089
D002104Cadmium"6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [Cadmium inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]]"10866824
D002104CadmiumAcetylcysteine inhibits the reaction [Cadmium inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]]10866824
D002104CadmiumCadmium inhibits the reaction [Cobalt results in increased expression of HIF1A protein]10866824
D002104CadmiumCadmium inhibits the reaction [Deferoxamine results in increased expression of HIF1A protein]10866824
D002104CadmiumCadmium inhibits the reaction [Oxygen deficiency promotes the reaction [HIF1A protein binds to EPO promoter]]10866824
D002104CadmiumCadmium inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]10866824
D002104CadmiumCadmium results in increased expression of HIF1A protein22884995
D019256Cadmium Chloride2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Cadmium Chloride results in increased expression of HIF1A protein]21984483
D019256Cadmium ChlorideCadmium Chloride affects the activity of HIF1A protein25596134
D019256Cadmium ChlorideCadmium Chloride affects the expression of HIF1A mRNA20580663
D019256Cadmium ChlorideCadmium Chloride inhibits the reaction [cobaltous chloride results in increased activity of HIF1A protein]11090055
D019256Cadmium ChlorideCadmium Chloride inhibits the reaction [Oxygen deficiency results in increased activity of HIF1A protein]11090055
D019256Cadmium ChlorideCadmium Chloride results in increased expression of HIF1A mRNA23811327
D019256Cadmium ChlorideCadmium Chloride results in increased expression of HIF1A protein21984483|2763445
D019256Cadmium Chloridediphenyleneiodonium inhibits the reaction [Cadmium Chloride results in increased expression of HIF1A protein]21984483
D019256Cadmium ChlorideSirolimus inhibits the reaction [Cadmium Chloride results in increased expression of HIF1A protein]21984483
D019256Cadmium ChlorideU 0126 inhibits the reaction [Cadmium Chloride results in increased expression of HIF1A protein]21984483
D019256Cadmium ChlorideCadmium Chloride inhibits the reaction [Oxygen deficiency affects the localization of HIF1A protein]15967517
D019256Cadmium ChlorideCadmium Chloride inhibits the reaction [cobaltous chloride promotes the reaction [HIF1A protein binds to LOX promoter]]23161664
D019256Cadmium ChlorideCadmium Chloride inhibits the reaction [cobaltous chloride results in increased activity of HIF1A protein]14980978
D019256Cadmium ChlorideCadmium Chloride inhibits the reaction [[cobaltous chloride results in increased activity of HIF1A protein] which results in decreased susceptibility to Hydrazines]14980978
D019256Cadmium ChlorideCadmium Chloride inhibits the reaction [cobaltous chloride results in increased expression of HIF1A mRNA]23161664
D019256Cadmium ChlorideCAT protein inhibits the reaction [Cadmium Chloride results in increased expression of HIF1A protein]21984483
C526426calycosin-7-O-beta-D-glucosidecalycosin-7-O-beta-D-glucoside results in increased expression of and results in decreased degradation of HIF1A protein21309574
C526426calycosin-7-O-beta-D-glucosidecalycosin-7-O-beta-D-glucoside results in increased expression of HIF1A mRNA21309574
D000069287CapecitabineHIF1A protein results in decreased susceptibility to Capecitabine16734730
D002211CapsaicinCapsaicin results in increased expression of HIF1A mRNA12242509
C098734carbobenzoxy-leucyl-leucyl-leucinecarbobenzoxy-leucyl-leucyl-leucine results in increased expression of HIF1A protein10866824
C098734carbobenzoxy-leucyl-leucyl-leucinecarbobenzoxy-leucyl-leucyl-leucine results in decreased expression of HIF1A mRNA12595275
C098734carbobenzoxy-leucyl-leucyl-leucinecarbobenzoxy-leucyl-leucyl-leucine results in increased expression of HIF1A protein12595275
C098734carbobenzoxy-leucyl-leucyl-leucineVitamin K 3 inhibits the reaction [carbobenzoxy-leucyl-leucyl-leucine results in increased expression of HIF1A protein]12595275
C098734carbobenzoxy-leucyl-leucyl-leucine[Xanthine co-treated with XDH protein] inhibits the reaction [carbobenzoxy-leucyl-leucyl-leucine results in increased expression of HIF1A protein]12595275
D002251Carbon TetrachlorideHIF1A protein affects the reaction [Carbon Tetrachloride results in increased expression of ACTA2 mRNA]24639359
D002251Carbon TetrachlorideHIF1A protein affects the reaction [Carbon Tetrachloride results in increased expression of ACTA2 protein]24639359
D002251Carbon TetrachlorideHIF1A protein affects the reaction [Carbon Tetrachloride results in increased expression of CCL3 mRNA]24639359
D002251Carbon TetrachlorideHIF1A protein affects the reaction [Carbon Tetrachloride results in increased expression of CCL4 mRNA]24639359
D002251Carbon TetrachlorideHIF1A protein affects the reaction [Carbon Tetrachloride results in increased expression of COL1A1 mRNA]24639359
D002251Carbon TetrachlorideHIF1A protein affects the reaction [Carbon Tetrachloride results in increased expression of CXCL1 mRNA]24639359
D002251Carbon TetrachlorideHIF1A protein affects the reaction [Carbon Tetrachloride results in increased expression of CXCL2 mRNA]24639359
D002251Carbon TetrachlorideHIF1A protein affects the reaction [Carbon Tetrachloride results in increased expression of MMP13 mRNA]24639359
D002251Carbon TetrachlorideHIF1A protein affects the reaction [Carbon Tetrachloride results in increased expression of NOS2 mRNA]24639359
D002251Carbon TetrachlorideHIF1A protein affects the reaction [Carbon Tetrachloride results in increased expression of PLAU mRNA]24639359
D002251Carbon TetrachlorideHIF1A protein affects the reaction [Carbon Tetrachloride results in increased expression of TNF mRNA]24639359
D002251Carbon TetrachlorideCarbon Tetrachloride results in increased expression of HIF1A mRNA16713642|2384585
D002251Carbon TetrachlorideCarbon Tetrachloride results in increased expression of HIF1A protein23845850
D002251Carbon TetrachlorideCurcumin inhibits the reaction [Carbon Tetrachloride results in increased expression of HIF1A mRNA]23845850
D002251Carbon TetrachlorideCurcumin inhibits the reaction [Carbon Tetrachloride results in increased expression of HIF1A protein]23845850
D002330Carmustine[cobaltous chloride results in increased activity of HIF1A protein] which results in decreased susceptibility to Carmustine14980978
D002330Carmustine[Deferoxamine results in increased activity of HIF1A protein] which results in decreased susceptibility to Carmustine14980978
D002330CarmustineHIF1A protein results in decreased susceptibility to Carmustine15965067
D002336CarnosineCarnosine inhibits the reaction [Sodium Nitrite results in increased expression of HIF1A protein]28266762
D002392Catechin[Catechin co-treated with Grape Seed Proanthocyanidins] results in increased expression of HIF1A mRNA24763279
C532683CellfoodCellfood affects the activity of HIF1A protein21893688
C532683CellfoodCellfood results in decreased expression of HIF1A protein24016597
D057846Cell-Penetrating Peptides[Cell-Penetrating Peptides binds to ARNT protein] inhibits the reaction [cobaltous chloride results in increased activity of HIF1A protein]23454269
D057846Cell-Penetrating Peptides[Cell-Penetrating Peptides binds to ARNT protein] inhibits the reaction [HIF1A protein binds to ARNT protein]23454269
D057846Cell-Penetrating Peptides[[Cell-Penetrating Peptides binds to ARNT protein] inhibits the reaction [HIF1A protein binds to ARNT protein]] which results in decreased activity of HIF1A protein23454269
D057846Cell-Penetrating Peptides[Cell-Penetrating Peptides binds to ARNT protein] which results in decreased activity of HIF1A protein23454269
D002614Chelating AgentsChelating Agents results in increased expression of HIF1A16046841
D002635Chenodeoxycholic AcidHIF1A mutant form inhibits the reaction [Chenodeoxycholic Acid results in increased expression of SLC51A mRNA]24703425
C001598chetominchetomin inhibits the reaction [HIF1A protein promotes the reaction [Lipopolysaccharides results in increased expression of VEGFA protein]]19744167
C001598chetominchetomin inhibits the reaction [HIF1A protein promotes the reaction [TNF protein results in decreased metabolism of Oxygen]]19744167
C001598chetominchetomin results in decreased expression of HIF1A mRNA19744167
D002706ChlordanChlordan results in decreased expression of HIF1A mRNA23153324
C004656chloroacetaldehydechloroacetaldehyde affects the activity of HIF1A protein25596134
D002746ChlorpromazineChlorpromazine affects the activity of HIF1A protein25596134
D002784Cholesterol[cocoa butter co-treated with Sodium Cholate co-treated with Cholesterol] results in increased expression of HIF1A mRNA26606054
D002794Choline[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of HIF1A gene20938992
D002857ChromiumChromium results in increased expression of HIF1A protein16386771
D002857Chromiumferrous sulfate inhibits the reaction [Chromium results in increased expression of HIF1A protein]16386771
D002857Chromium[Nickel co-treated with Chromium] results in increased expression of HIF1A protein16386771
C074702chromium hexavalent ionAscorbic Acid inhibits the reaction [chromium hexavalent ion results in increased stability of HIF1A protein]17382205
C074702chromium hexavalent ion[chromium hexavalent ion co-treated with nickel sulfate] results in increased expression of HIF1A protein17382205
C074702chromium hexavalent ionchromium hexavalent ion inhibits the reaction [Nickel results in increased stability of and results in increased expression of HIF1A protein]19403854
C074702chromium hexavalent ionchromium hexavalent ion results in increased expression of and affects the localization of HIF1A protein17382205
C074702chromium hexavalent ionchromium hexavalent ion results in increased expression of HIF1A mRNA19616015|2544843
C074702chromium hexavalent ionchromium hexavalent ion results in increased expression of HIF1A protein23748240|2544843
C074702chromium hexavalent ionchromium hexavalent ion results in increased stability of HIF1A protein17382205
C074702chromium hexavalent ionLuteolin inhibits the reaction [chromium hexavalent ion results in increased expression of HIF1A mRNA]25448439
C074702chromium hexavalent ionLuteolin inhibits the reaction [chromium hexavalent ion results in increased expression of HIF1A protein]25448439
C074702chromium hexavalent ionMIR143 inhibits the reaction [chromium hexavalent ion results in increased expression of HIF1A protein]23748240
C074702chromium hexavalent ionSTAT1 protein affects the reaction [chromium hexavalent ion inhibits the reaction [Nickel results in increased stability of and results in increased expression of HIF1A protein]]19403854
C011585ciclopiroxciclopirox results in increased stability of HIF1A protein15741220
C011585ciclopiroxciclopirox results in increased expression of and results in increased localization of HIF1A protein14600837
C059262cidofovircidofovir affects the activity of HIF1A protein25596134
C039671ciglitazoneciglitazone results in decreased expression of HIF1A mRNA22193206
C011730clay[clay analog co-treated with deoxynivalenol] results in decreased expression of HIF1A mRNA23922676
C011730clayclay analog results in decreased expression of HIF1A mRNA23922676
D007464ClioquinolClioquinol inhibits the reaction [HIF1AN protein results in increased hydroxylation of HIF1A protein]16973622
D007464ClioquinolClioquinol results in decreased hydroxylation of HIF1A protein16973622
D007464ClioquinolClioquinol results in decreased ubiquitination of HIF1A protein16973622
D007464ClioquinolClioquinol results in increased activity of HIF1A protein19502547
D007464ClioquinolClioquinol results in increased expression of HIF1A protein16973622
D007464Clioquinol[Zinc co-treated with Copper] inhibits the reaction [Clioquinol results in increased expression of HIF1A protein]16973622
D007464Clioquinol"[Clioquinol co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in increased expression of HIF1A protein"19679656
D007464ClioquinolClioquinol results in increased expression of HIF1A protein19679656
D007464ClioquinolHIF1A protein promotes the reaction [Clioquinol results in increased expression of VEGFA protein]19502547
D004002Clodronic AcidClodronic Acid affects the activity of HIF1A protein25596134
D004002Clodronic AcidClodronic Acid inhibits the reaction [Dopamine results in decreased expression of HIF1A protein]25818600
D002994ClofibrateClofibrate results in decreased activity of HIF1A protein19528198
D002994ClofibrateClofibrate affects the expression of HIF1A mRNA16081524
D003035Cobalt3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole inhibits the reaction [Cobalt results in increased expression of HIF1A protein]11286986
D003035Cobaltbisphenol A inhibits the reaction [Cobalt results in decreased ubiquitination of and results in decreased degradation of HIF1A protein]15147973
D003035CobaltCadmium inhibits the reaction [Cobalt results in increased expression of HIF1A protein]10866824
D003035CobaltCobalt results in decreased ubiquitination of and results in decreased degradation of HIF1A protein15147973
D003035CobaltCobalt results in increased expression of and results in increased stability of HIF1A protein23052192|2449796
D003035CobaltCobalt results in increased expression of HIF1A protein10866824|1128698
D003035CobaltCobalt results in increased stability of and results in increased expression of and results in increased activity of HIF1A protein16386771
D003035CobaltCobalt results in increased stability of HIF1A protein16877034
D003035CobaltCycloheximide promotes the reaction [Cobalt results in increased expression of HIF1A protein]24497960
D003035Cobaltferrous sulfate inhibits the reaction [Cobalt results in increased expression of HIF1A protein]16386771
D003035CobaltHIF1A protein promotes the reaction [Cobalt results in increased expression of NDRG1 mRNA]15341671
D003035CobaltHIF1A protein promotes the reaction [Cobalt results in increased expression of NDRG1 protein]15341671
D003035Cobalt[tungsten carbide co-treated with Cobalt] results in increased expression of and results in increased stability of HIF1A protein23052192
D003035CobaltCobalt results in increased expression of HIF1A mRNA17967803
D003035CobaltCobalt results in increased expression of HIF1A protein17967803
D003035CobaltCobalt inhibits the reaction [HIF1A protein modified form binds to VHL protein]12606543
D003035CobaltCobalt results in increased activity of [ARNT protein binds to HIF1A protein]11739637
D003035CobaltCobalt results in increased expression of HIF1A protein12606543
C521309cobalt(II) acetatecobalt(II) acetate results in increased expression of HIF1A protein16357179
C007095cobaltiprotoporphyrincobaltiprotoporphyrin inhibits the reaction [IL1B protein results in increased expression of HIF1A protein]23406266
C491689cobalt-nickel-chromium-molybdenum alloycobalt-nickel-chromium-molybdenum alloy results in increased expression of HIF1A protein23840602
C018021cobaltous chloridecobaltous chloride results in increased expression of HIF1A mRNA28964603
C018021cobaltous chloridecobaltous chloride results in increased expression of HIF1A protein28964603
C018021cobaltous chloridecobaltous chloride affects the localization of HIF1A protein15967517
C018021cobaltous chloridecobaltous chloride inhibits the reaction [Oxygen results in increased degradation of HIF1A protein]15967517
C018021cobaltous chloridecobaltous chloride results in decreased degradation of HIF1A protein15967517
C018021cobaltous chloridecobaltous chloride results in increased expression of HIF1A protein15967517
C018021cobaltous chloride103D5R inhibits the reaction [cobaltous chloride results in increased expression of HIF1A protein]15695405
C018021cobaltous chloride"15,16-dihydrotanshinone I inhibits the reaction [cobaltous chloride results in increased expression of HIF1A protein]"26282490
C018021cobaltous chloride2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [cobaltous chloride results in increased activity of HIF1A protein]19808899
C018021cobaltous chloride2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [cobaltous chloride results in increased expression of HIF1A protein]17015263
C018021cobaltous chloride2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [cobaltous chloride results in increased activity of HIF1A protein]17082639|1980889
C018021cobaltous chloride2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [cobaltous chloride results in increased expression of HIF1A protein]17015263|1708263
C018021cobaltous chloride"6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [cobaltous chloride results in increased expression of HIF1A protein]"17015263
C018021cobaltous chlorideAcetylcysteine inhibits the reaction [cobaltous chloride results in increased expression of HIF1A protein]11886167|1367921
C018021cobaltous chlorideAG 1879 inhibits the reaction [[cobaltous chloride results in increased activity of SRC protein] which results in increased expression of HIF1A protein]15735682
C018021cobaltous chlorideAmino Acids inhibits the reaction [cobaltous chloride results in increased expression of HIF1A protein]21036805
C018021cobaltous chloride[andrographolide co-treated with cobaltous chloride] results in increased hydroxylation of HIF1A protein27297870
C018021cobaltous chlorideandrographolide inhibits the reaction [cobaltous chloride results in increased expression of HIF1A mRNA]27297870
C018021cobaltous chloridearsenic trioxide promotes the reaction [cobaltous chloride results in increased expression of HIF1A protein]16330433
C018021cobaltous chlorideBenzo(a)pyrene inhibits the reaction [cobaltous chloride affects the localization of HIF1A protein]26350169
C018021cobaltous chlorideBenzo(a)pyrene inhibits the reaction [cobaltous chloride promotes the reaction [HIF1A protein binds to ARNT protein]]20228066
C018021cobaltous chloridebenzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [scutellarin inhibits the reaction [[cobaltous chloride co-treated with Glucose] results in increased expression of HIF1A protein]]25192544
C018021cobaltous chlorideBilirubin inhibits the reaction [cobaltous chloride results in increased expression of HIF1A mRNA]27297870
C018021cobaltous chlorideBilirubin inhibits the reaction [cobaltous chloride results in increased expression of HIF1A protein]27297870
C018021cobaltous chlorideCadmium Chloride inhibits the reaction [cobaltous chloride results in increased activity of HIF1A protein]11090055
C018021cobaltous chlorideCisplatin inhibits the reaction [cobaltous chloride results in increased activity of HIF1A protein]11090055
C018021cobaltous chloridecobaltous chloride affects the localization of HIF1A protein19196431|2186306
C018021cobaltous chloride[cobaltous chloride co-treated with Glucose] promotes the reaction [HIF1A protein binds to EP300 protein]25192544
C018021cobaltous chloride[cobaltous chloride co-treated with Glucose] results in increased expression of and results in decreased ubiquitination of HIF1A protein25192544
C018021cobaltous chloride[cobaltous chloride co-treated with VEGFA protein] results in increased expression of HIF1A protein16499871
C018021cobaltous chloridecobaltous chloride inhibits the reaction [Doxorubicin promotes the reaction [HIPK2 protein binds to HIF1A promoter]]19714248
C018021cobaltous chloridecobaltous chloride inhibits the reaction [HDAC1 protein binds to HIF1A promoter]19714248
C018021cobaltous chloridecobaltous chloride inhibits the reaction [HIPK2 protein binds to HIF1A promoter]19714248
C018021cobaltous chloridecobaltous chloride promotes the reaction [HIF1A protein binds to ARNT protein]20228066
C018021cobaltous chloridecobaltous chloride promotes the reaction [HIF1A protein binds to ARNT protein binds to EDN1 promoter]10939628
C018021cobaltous chloridecobaltous chloride promotes the reaction [HIF1A protein binds to CD36 promoter]19640849
C018021cobaltous chloridecobaltous chloride promotes the reaction [HIF1A protein binds to CXCL8 promoter]17082639
C018021cobaltous chloridecobaltous chloride promotes the reaction [HIF1A protein binds to MME gene]23138928
C018021cobaltous chloridecobaltous chloride promotes the reaction [HIF1A protein binds to VEGFA gene]23138928
C018021cobaltous chloridecobaltous chloride promotes the reaction [HIF1A protein results in increased expression of ABCB1 mRNA]19128456
C018021cobaltous chloridecobaltous chloride promotes the reaction [HIF1A protein results in increased expression of BCL2 mRNA]19128456
C018021cobaltous chloridecobaltous chloride promotes the reaction [HIF1A protein results in increased expression of CTGF mRNA]17034590
C018021cobaltous chloridecobaltous chloride promotes the reaction [HIF1A protein results in increased expression of CTGF protein]17034590
C018021cobaltous chloridecobaltous chloride promotes the reaction [HIF1A protein results in increased expression of EPO mRNA]19128456
C018021cobaltous chloride[cobaltous chloride results in decreased abundance of Oxygen] which results in increased expression of HIF1A mRNA22269387|2332641
C018021cobaltous chloride[cobaltous chloride results in decreased abundance of Oxygen] which results in increased expression of HIF1A protein22269387
C018021cobaltous chloridecobaltous chloride results in decreased degradation of and results in increased activity of HIF1A protein19128456
C018021cobaltous chloridecobaltous chloride results in decreased degradation of HIF1A protein19695866|2004264
C018021cobaltous chloridecobaltous chloride results in decreased expression of HIF1A mRNA19320972
C018021cobaltous chloridecobaltous chloride results in decreased expression of HIF1A protein16775626
C018021cobaltous chloridecobaltous chloride results in increased activity of HIF1A protein11090055|1560427
C018021cobaltous chloride[cobaltous chloride results in increased activity of SRC protein] promotes the reaction [[HIF1A protein binds to STAT3 protein modified form] which binds to VEGFA promoter]15735682
C018021cobaltous chloride[cobaltous chloride results in increased activity of SRC protein] promotes the reaction [[[HIF1A protein binds to STAT3 protein modified form] which binds to VEGFA promoter] binds to [APEX1 protein binds to CREBBP promoter]]15735682
C018021cobaltous chloride[cobaltous chloride results in increased activity of SRC protein] which results in increased expression of HIF1A protein15735682
C018021cobaltous chloridecobaltous chloride results in increased expression of and affects the localization of HIF1A protein26174737|2635016
C018021cobaltous chloridecobaltous chloride results in increased expression of and results in increased activity of HIF1A protein19808899
C018021cobaltous chloridecobaltous chloride results in increased expression of and results in increased secretion of HIF1A protein22652775
C018021cobaltous chloride[cobaltous chloride results in increased expression of EPAS1 protein] which results in decreased expression of HIF1A protein25805230
C018021cobaltous chloridecobaltous chloride results in increased expression of HIF1A mRNA16504308|1685912
C018021cobaltous chloridecobaltous chloride results in increased expression of HIF1A protein11886167|1281183
C018021cobaltous chloride[cobaltous chloride results in increased expression of HIF1A protein] which results in decreased expression of EPAS1 protein25805230
C018021cobaltous chloride[Cycloheximide co-treated with cobaltous chloride] results in decreased expression of HIF1A protein22537771
C018021cobaltous chlorideCycloheximide inhibits the reaction [[cobaltous chloride co-treated with Glucose] results in increased expression of HIF1A protein]25192544
C018021cobaltous chloride[Cyclosporine co-treated with cobaltous chloride] results in increased expression of HIF1A protein22343435
C018021cobaltous chlorideCyclosporine inhibits the reaction [cobaltous chloride results in increased activity of HIF1A protein]16682453
C018021cobaltous chlorideepoxomicin inhibits the reaction [scutellarin inhibits the reaction [[cobaltous chloride co-treated with Glucose] results in increased expression of HIF1A protein]]25192544
C018021cobaltous chlorideFlavanones inhibits the reaction [cobaltous chloride results in increased expression of HIF1A protein]25446852
C018021cobaltous chloridegeldanamycin inhibits the reaction [cobaltous chloride results in increased expression of HIF1A protein]12811834
C018021cobaltous chlorideGenistein affects the reaction [cobaltous chloride promotes the reaction [HIF1A protein binds to ARNT protein binds to EDN1 promoter]]10939628
C018021cobaltous chloride[Gentamicins co-treated with cobaltous chloride] results in increased expression of HIF1A protein23145036
C018021cobaltous chlorideGlutathione Disulfide analog promotes the reaction [cobaltous chloride results in increased activity of HIF1A protein]19374849
C018021cobaltous chlorideHIF1A mutant form inhibits the reaction [cobaltous chloride results in increased expression of BNIP3 mRNA]25100165
C018021cobaltous chlorideHIF1A mutant form inhibits the reaction [cobaltous chloride results in increased expression of IGF2 mRNA]25100165
C018021cobaltous chlorideHIF1A protein affects the reaction [cobaltous chloride results in decreased expression of S100A1 protein]24244340
C018021cobaltous chlorideHIF1A protein affects the reaction [cobaltous chloride results in increased expression of DDIT4 mRNA]17307335
C018021cobaltous chlorideHIF1A protein affects the reaction [cobaltous chloride results in increased expression of HIF1A protein]17307335
C018021cobaltous chlorideHIF1A protein affects the reaction [cobaltous chloride results in increased expression of VEGFA mRNA]17307335
C018021cobaltous chlorideHIF1A protein promotes the reaction [cobaltous chloride results in decreased expression of MME mRNA]23138928
C018021cobaltous chlorideHIF1A protein promotes the reaction [cobaltous chloride results in decreased expression of MME protein]23138928
C018021cobaltous chlorideHIF1A protein promotes the reaction [cobaltous chloride results in increased expression of EPO mRNA]23065176
C018021cobaltous chlorideHIF1A protein promotes the reaction [SP1 protein promotes the reaction [cobaltous chloride results in increased expression of DDIT4]]17307335
C018021cobaltous chlorideHIF1A protein results in increased susceptibility to cobaltous chloride23065176|2580523
C018021cobaltous chloride[HIF1A protein results in increased susceptibility to cobaltous chloride] which results in increased expression of CD44 mRNA25805230
C018021cobaltous chloride[HIF1A protein results in increased susceptibility to cobaltous chloride] which results in increased expression of NANOG mRNA25805230
C018021cobaltous chloride[HIF1A protein results in increased susceptibility to cobaltous chloride] which results in increased expression of POU5F1 mRNA25805230
C018021cobaltous chloride[HIF1A protein results in increased susceptibility to cobaltous chloride] which results in increased expression of PROM1 mRNA25805230
C018021cobaltous chloride[HIF1A protein results in increased susceptibility to cobaltous chloride] which results in increased expression of SOX2 mRNA25805230
C018021cobaltous chlorideHIPK2 protein inhibits the reaction [cobaltous chloride promotes the reaction [HIF1A protein results in increased expression of ABCB1 mRNA]]19128456
C018021cobaltous chlorideHIPK2 protein inhibits the reaction [cobaltous chloride promotes the reaction [HIF1A protein results in increased expression of BCL2 mRNA]]19128456
C018021cobaltous chlorideHIPK2 protein inhibits the reaction [cobaltous chloride promotes the reaction [HIF1A protein results in increased expression of EPO mRNA]]19128456
C018021cobaltous chlorideHIPK2 protein inhibits the reaction [cobaltous chloride results in decreased degradation of and results in increased activity of HIF1A protein]19128456
C018021cobaltous chlorideHMOX1 protein affects the reaction [andrographolide inhibits the reaction [cobaltous chloride results in increased expression of HIF1A mRNA]]27297870
C018021cobaltous chlorideIGF1 protein promotes the reaction [cobaltous chloride results in increased expression of HIF1A protein]16499871
C018021cobaltous chlorideIndican inhibits the reaction [cobaltous chloride affects the localization of HIF1A protein]21863063
C018021cobaltous chlorideL-4F peptide inhibits the reaction [cobaltous chloride results in increased expression of HIF1A protein]22537771
C018021cobaltous chlorideL-4F peptide promotes the reaction [[Cycloheximide co-treated with cobaltous chloride] results in decreased expression of HIF1A protein]22537771
C018021cobaltous chlorideMercuric Chloride inhibits the reaction [cobaltous chloride results in increased activity of HIF1A protein]11090055
C018021cobaltous chlorideMG 262 inhibits the reaction [scutellarin inhibits the reaction [[cobaltous chloride co-treated with Glucose] results in increased expression of HIF1A protein]]25192544
C018021cobaltous chloride"Mn(III) 5,10,15,20-tetrakis(N-methylpyridinium-2-yl)porphyrin inhibits the reaction [cobaltous chloride results in increased expression of HIF1A protein]"21036805
C018021cobaltous chlorideNFE2L2 protein affects the reaction [andrographolide inhibits the reaction [cobaltous chloride results in increased expression of HIF1A mRNA]]27297870
C018021cobaltous chloridePDK4 protein affects the reaction [cobaltous chloride results in increased expression of HIF1A protein]25630799
C018021cobaltous chloridepeoniflorin inhibits the reaction [[cobaltous chloride results in decreased abundance of Oxygen] which results in increased expression of HIF1A mRNA]22269387
C018021cobaltous chloridepeoniflorin inhibits the reaction [[cobaltous chloride results in decreased abundance of Oxygen] which results in increased expression of HIF1A protein]22269387
C018021cobaltous chloridepeptide 5F inhibits the reaction [cobaltous chloride results in increased expression of HIF1A protein]22537771
C018021cobaltous chlorideplastochromanol 8 inhibits the reaction [cobaltous chloride results in increased expression of HIF1A protein]20452389
C018021cobaltous chloridePTEN protein inhibits the reaction [cobaltous chloride results in increased activity of HIF1A protein]19808899
C018021cobaltous chloridePTGES protein promotes the reaction [cobaltous chloride results in increased expression of HIF1A mRNA]20042640
C018021cobaltous chlorideR 59949 inhibits the reaction [cobaltous chloride results in increased activity of HIF1A protein]17082639
C018021cobaltous chlorideR 59949 inhibits the reaction [cobaltous chloride results in increased expression of HIF1A protein]17082639
C018021cobaltous chlorideReactive Oxygen Species affects the reaction [cobaltous chloride results in increased expression of HIF1A protein]17015263
C018021cobaltous chlorideresveratrol inhibits the reaction [cobaltous chloride results in increased expression of HIF1A protein]25815440|2617495
C018021cobaltous chloriderhein inhibits the reaction [cobaltous chloride results in increased expression of HIF1A protein]21457705
C018021cobaltous chlorideromidepsin inhibits the reaction [cobaltous chloride results in increased expression of HIF1A protein]21295294
C018021cobaltous chloridesauchinone inhibits the reaction [cobaltous chloride results in increased expression of HIF1A protein]25451574|2787189
C018021cobaltous chlorideSB 203580 inhibits the reaction [cobaltous chloride results in increased activity of HIF1A protein]17082639
C018021cobaltous chlorideSB 203580 inhibits the reaction [cobaltous chloride results in increased expression of HIF1A mRNA]27297870
C018021cobaltous chlorideSB 203580 inhibits the reaction [cobaltous chloride results in increased expression of HIF1A protein]17082639|2729787
C018021cobaltous chloridescutellarin inhibits the reaction [[cobaltous chloride co-treated with Glucose co-treated with Cycloheximide] results in decreased expression of HIF1A protein]25192544
C018021cobaltous chloridescutellarin inhibits the reaction [[cobaltous chloride co-treated with Glucose] promotes the reaction [HIF1A protein binds to EP300 protein]]25192544
C018021cobaltous chloridescutellarin inhibits the reaction [[cobaltous chloride co-treated with Glucose] results in increased expression of and results in decreased ubiquitination of HIF1A protein]25192544
C018021cobaltous chloridescutellarin promotes the reaction [Cycloheximide inhibits the reaction [[cobaltous chloride co-treated with Glucose] results in increased expression of HIF1A protein]]25192544
C018021cobaltous chlorideSIRT1 protein promotes the reaction [resveratrol inhibits the reaction [cobaltous chloride results in increased expression of HIF1A protein]]26174951
C018021cobaltous chloridetetraethylenepentamine inhibits the reaction [cobaltous chloride results in increased activity of HIF1A protein]26174737
C018021cobaltous chloridetetraethylenepentamine inhibits the reaction [cobaltous chloride results in increased expression of and affects the localization of HIF1A protein]26174737
C018021cobaltous chlorideTP53 gene mutant form promotes the reaction [cobaltous chloride results in increased expression of HIF1A protein]16527254
C018021cobaltous chloridetricarbonyldichlororuthenium (II) dimer inhibits the reaction [cobaltous chloride results in increased expression of HIF1A mRNA]27297870
C018021cobaltous chloridetricarbonyldichlororuthenium (II) dimer inhibits the reaction [cobaltous chloride results in increased expression of HIF1A protein]27297870
C018021cobaltous chlorideU 0126 inhibits the reaction [cobaltous chloride results in increased expression of HIF1A protein]20452389
C018021cobaltous chloride[wortmannin co-treated with U 0126] inhibits the reaction [IGF1 protein promotes the reaction [cobaltous chloride results in increased expression of HIF1A protein]]16499871
C018021cobaltous chloridewortmannin inhibits the reaction [cobaltous chloride results in increased expression of HIF1A protein]13679210
C018021cobaltous chloridezinc chloride inhibits the reaction [cobaltous chloride inhibits the reaction [Doxorubicin promotes the reaction [HIPK2 protein binds to HIF1A promoter]]]19714248
C018021cobaltous chloridezinc chloride inhibits the reaction [cobaltous chloride results in increased expression of HIF1A protein]19714248
C018021cobaltous chlorideZM323881 inhibits the reaction [[cobaltous chloride co-treated with VEGFA protein] results in increased expression of HIF1A protein]16499871
C018021cobaltous chloridecobaltous chloride results in increased expression of HIF1A16046841
C018021cobaltous chloride3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole inhibits the reaction [cobaltous chloride results in decreased expression of HIF1A protein]24265542
C018021cobaltous chloride3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole inhibits the reaction [cobaltous chloride results in increased expression of HIF1A protein]24265542
C018021cobaltous chloridecobaltous chloride affects the localization of HIF1A protein16772336
C018021cobaltous chloridecobaltous chloride inhibits the reaction [3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole results in increased expression of HIF1A mRNA]24265542
C018021cobaltous chloridecobaltous chloride promotes the reaction [[HIF1A protein binds to IL1B promoter] which results in increased expression of IL1B mRNA]16504308
C018021cobaltous chloridecobaltous chloride results in decreased expression of HIF1A mRNA24265542
C018021cobaltous chloridecobaltous chloride results in decreased expression of HIF1A protein24265542
C018021cobaltous chloridecobaltous chloride results in increased activity of HIF1A protein16772336
C018021cobaltous chloridecobaltous chloride results in increased expression of HIF1A mRNA16504308|1650759
C018021cobaltous chloridecobaltous chloride results in increased expression of HIF1A protein12479793|1650430
C018021cobaltous chloridecobaltous chloride results in increased stability of HIF1A protein17169330|2085041
C018021cobaltous chlorideEchinomycin inhibits the reaction [cobaltous chloride results in increased activity of HIF1A protein]16772336
C018021cobaltous chlorideHIF1A gene mutant form inhibits the reaction [cobaltous chloride affects the secretion of APLN protein]17878221
C018021cobaltous chlorideHIF1A inhibits the reaction [cobaltous chloride results in increased expression of IL10 protein]20511350
C018021cobaltous chlorideHIF1A inhibits the reaction [cobaltous chloride results in increased expression of IL4 protein]20511350
C018021cobaltous chlorideHIF1A inhibits the reaction [cobaltous chloride results in increased expression of IL5 protein]20511350
C018021cobaltous chlorideHIF1A promotes the reaction [cobaltous chloride results in increased expression of IL6 protein]20511350
C018021cobaltous chlorideHIF1A promotes the reaction [cobaltous chloride results in increased expression of TNF protein]20511350
C018021cobaltous chlorideHIF1A protein affects the reaction [cobaltous chloride results in increased expression of GAPDH mRNA]10646848
C018021cobaltous chlorideHIF1A protein affects the reaction [cobaltous chloride results in increased expression of NDRG1 mRNA]10646848
C018021cobaltous chlorideHIF1A protein promotes the reaction [cobaltous chloride promotes the reaction [GDF2 protein results in increased activity of ALPL protein]]23203800
C018021cobaltous chlorideHIF1A protein promotes the reaction [cobaltous chloride results in increased expression of VEGFA protein]19502547
C018021cobaltous chlorideHIF1A protein results in increased susceptibility to cobaltous chloride15375294
C018021cobaltous chlorideY 27632 promotes the reaction [cobaltous chloride affects the localization of HIF1A protein]16772336
C018021cobaltous chloridecobaltous chloride promotes the reaction [Oxygen deficiency results in increased expression of HIF1A protein]15967517
C018021cobaltous chloridecobaltous chloride results in decreased degradation of HIF1A protein15967517
C018021cobaltous chloridecobaltous chloride results in increased expression of HIF1A protein14729976|1596751
C018021cobaltous chlorideCadmium Chloride inhibits the reaction [cobaltous chloride promotes the reaction [HIF1A protein binds to LOX promoter]]23161664
C018021cobaltous chlorideCadmium Chloride inhibits the reaction [cobaltous chloride results in increased activity of HIF1A protein]14980978
C018021cobaltous chlorideCadmium Chloride inhibits the reaction [[cobaltous chloride results in increased activity of HIF1A protein] which results in decreased susceptibility to Hydrazines]14980978
C018021cobaltous chlorideCadmium Chloride inhibits the reaction [cobaltous chloride results in increased expression of HIF1A mRNA]23161664
C018021cobaltous chloridecobaltous chloride affects the expression of HIF1A protein24309492
C018021cobaltous chloride[cobaltous chloride co-treated with Diethylnitrosamine] results in increased expression of HIF1A protein11751435
C018021cobaltous chloride[cobaltous chloride co-treated with NGF protein] results in increased expression of HIF1A protein24989011
C018021cobaltous chloridecobaltous chloride promotes the reaction [fisetin results in increased activity of HIF1A protein]25428606
C018021cobaltous chloridecobaltous chloride promotes the reaction [HIF1A protein binds to LOX promoter]23161664
C018021cobaltous chloridecobaltous chloride promotes the reaction [[HIF1A protein co-treated with ARNT protein] results in increased expression of LOX mRNA]23161664
C018021cobaltous chloridecobaltous chloride promotes the reaction [HIF1A protein results in increased expression of LOX mRNA]23161664
C018021cobaltous chloridecobaltous chloride results in increased activity of HIF1A protein25428606
C018021cobaltous chloride[cobaltous chloride results in increased activity of HIF1A protein] which results in decreased susceptibility to 2-chloroethyl isocyanate14980978
C018021cobaltous chloride[cobaltous chloride results in increased activity of HIF1A protein] which results in decreased susceptibility to Carmustine14980978
C018021cobaltous chloride[cobaltous chloride results in increased activity of HIF1A protein] which results in decreased susceptibility to cyclohexylisocyanate14980978
C018021cobaltous chloride[cobaltous chloride results in increased activity of HIF1A protein] which results in decreased susceptibility to Hydrazines14980978
C018021cobaltous chloridecobaltous chloride results in increased expression of and affects the localization of HIF1A protein21499890
C018021cobaltous chloridecobaltous chloride results in increased expression of and results in decreased degradation of and results in increased activity of HIF1A protein21054399
C018021cobaltous chloridecobaltous chloride results in increased expression of and results in increased activity of HIF1A protein14980978|1927835
C018021cobaltous chloride[cobaltous chloride results in increased expression of and results in increased activity of HIF1A protein] which results in increased expression of EPO protein21054399
C018021cobaltous chloride[cobaltous chloride results in increased expression of and results in increased activity of HIF1A protein] which results in increased expression of VEGFA protein21054399
C018021cobaltous chloridecobaltous chloride results in increased expression of HIF1A mRNA12595275|1770683
C018021cobaltous chloridecobaltous chloride results in increased expression of HIF1A protein10559391|1259527
C018021cobaltous chloride[cobaltous chloride results in increased expression of HIF1A protein] which results in increased expression of HMOX1 protein21054399
C018021cobaltous chloride[cobaltous chloride results in increased expression of HIF1A protein] which results in increased expression of MT1A protein21054399
C018021cobaltous chloridecobaltous chloride results in increased stability of HIF1A protein19324842
C018021cobaltous chloride[Cyclosporine co-treated with cobaltous chloride] results in increased expression of HIF1A protein22343435
C018021cobaltous chlorideEPO protein inhibits the reaction [cobaltous chloride results in increased expression of HIF1A protein]21116766
C018021cobaltous chloridefisetin promotes the reaction [cobaltous chloride results in increased activity of HIF1A protein]25428606
C018021cobaltous chloride[Gentamicins co-treated with cobaltous chloride] results in increased expression of HIF1A protein23145036
C018021cobaltous chlorideHIF1A mutant form inhibits the reaction [cobaltous chloride results in increased expression of LOX mRNA]23161664
C018021cobaltous chlorideR 59949 inhibits the reaction [rhodioloside promotes the reaction [cobaltous chloride results in increased expression of and affects the localization of HIF1A protein]]21499890
C018021cobaltous chloride[rhodioloside co-treated with cobaltous chloride co-treated with NGF protein] results in decreased expression of HIF1A mRNA24989011
C018021cobaltous chloriderhodioloside inhibits the reaction [[cobaltous chloride co-treated with NGF protein] results in increased expression of HIF1A protein]24989011
C018021cobaltous chloriderhodioloside promotes the reaction [cobaltous chloride results in increased expression of and affects the localization of HIF1A protein]21499890
C018021cobaltous chlorideVitamin K 3 inhibits the reaction [cobaltous chloride results in increased expression of HIF1A protein]12595275
C018021cobaltous chloride[Xanthine co-treated with XDH protein] inhibits the reaction [cobaltous chloride results in increased expression of HIF1A protein]12595275
C018021cobaltous chloride[Cell-Penetrating Peptides binds to ARNT protein] inhibits the reaction [cobaltous chloride results in increased activity of HIF1A protein]23454269
C018021cobaltous chloridecobaltous chloride results in decreased ubiquitination of HIF1A protein15277511
C018021cobaltous chloridecobaltous chloride results in increased expression of HIF1A16705796
C018021cobaltous chloridecobaltous chloride results in increased expression of HIF1A mRNA15277511
C026305cobalt sulfatecobalt sulfate results in increased activity of HIF1A protein19502547
C026305cobalt sulfateHIF1A protein promotes the reaction [cobalt sulfate results in increased expression of VEGFA protein]19502547
D003042CocaineCocaine results in decreased expression of HIF1A mRNA12629581
C052387cocoa butter[cocoa butter co-treated with Sodium Cholate co-treated with Cholesterol] results in increased expression of HIF1A mRNA26606054
D045424Complex Mixtures[Complex Mixtures co-treated with Sulfadimethoxine] results in increased expression of HIF1A mRNA22687987
C036978concanamycin Aconcanamycin A results in increased expression of HIF1A protein25981168
C036978concanamycin Alapatinib inhibits the reaction [concanamycin A results in increased expression of HIF1A protein]25981168
D003300CopperCopper results in increased expression of HIF1A mRNA24403277
D003300CopperCCS protein promotes the reaction [Copper results in increased activity of HIF1A protein]17339407
D003300CopperCCS protein promotes the reaction [[Copper results in increased activity of HIF1A protein] which results in increased expression of VEGFA protein]17339407
D003300CopperCopper results in increased activity of HIF1A protein17339407
D003300Copper[Copper results in increased activity of HIF1A protein] which results in increased expression of VEGFA protein17339407
D003300Copper[Zinc co-treated with Copper] inhibits the reaction [Clioquinol results in increased expression of HIF1A protein]16973622
D003300Copper[Copper deficiency co-treated with tetrathiomolybdate] inhibits the reaction [EP300 protein binds to HIF1A protein]22276220
D003300Copper[Copper deficiency co-treated with tetrathiomolybdate] results in decreased expression of HIF1A protein22276220
D003300CopperCopper results in increased stability of HIF1A protein19355887
D019327Copper SulfateCopper Sulfate affects the reaction [tetraethylenepentamine affects the localization of HIF1A protein]25687434
C467608CP-470711[CP-470711 results in decreased activity of SORD protein] which results in decreased expression of HIF1A protein18549825
C534043CR 32943-methyladenine inhibits the reaction [CR 3294 results in decreased expression of HIF1A protein]18927491
C534043CR 3294CR 3294 affects the localization of HIF1A protein18927491
C534043CR 3294CR 3294 results in decreased expression of HIF1A protein18927491
C534043CR 3294wortmannin inhibits the reaction [CR 3294 results in decreased expression of HIF1A protein]18927491
D016578Crack CocaineCrack Cocaine results in increased expression of HIF1A mRNA12629581
C048923crystal violet lactonecrystal violet lactone results in increased activity of HIF1A protein19502547
C029892cupric chloridecupric chloride results in increased expression of HIF1A mRNA26684263
C029892cupric chlorideAscorbic Acid inhibits the reaction [cupric chloride results in decreased hydroxylation of HIF1A protein]19074761
C029892cupric chlorideAscorbic Acid inhibits the reaction [cupric chloride results in increased stability of HIF1A protein]19074761
C029892cupric chloridecupric chloride affects the localization of HIF1A protein15741220
C029892cupric chloridecupric chloride results in decreased hydroxylation of and results in decreased degradation of HIF1A protein15741220
C029892cupric chloridecupric chloride results in decreased hydroxylation of HIF1A protein19074761
C029892cupric chloridecupric chloride results in increased stability of HIF1A protein15741220|1907476
D003474Curcumin[Curcumin analog co-treated with Sirolimus] inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]20554536
D003474Curcumin[Curcumin analog co-treated with terpestacin] inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]20554536
D003474Curcumin[Curcumin analog co-treated with vorinostat] inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]20554536
D003474CurcuminCurcumin analog inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Oxygen deficiency results in increased expression of HIF1A protein]]20554536
D003474CurcuminCurcumin analog inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of HIF1A protein modified form]20554536
D003474CurcuminCurcumin analog inhibits the reaction [Ionomycin promotes the reaction [Oxygen deficiency results in increased activity of HIF1A protein]]20554536
D003474CurcuminCurcumin analog inhibits the reaction [Ionomycin results in increased activity of HIF1A protein]20554536
D003474CurcuminCurcumin analog inhibits the reaction [Oxygen deficiency results in increased expression of and results in increased activity of HIF1A protein]20554536
D003474CurcuminCurcumin analog results in decreased expression of HIF1A mRNA26409325
D003474CurcuminCurcumin results in decreased activity of HIF1A protein16880289
D003474CurcuminCurcumin results in decreased expression of and results in decreased activity of HIF1A protein18682687
D003474CurcuminCurcumin results in decreased expression of HIF1A mRNA18682687
D003474CurcuminVHL protein promotes the reaction [Curcumin results in decreased expression of HIF1A protein]18682687
D003474CurcuminCurcumin results in decreased expression of HIF1A mRNA21397623
D003474CurcuminCurcumin inhibits the reaction [Carbon Tetrachloride results in increased expression of HIF1A mRNA]23845850
D003474CurcuminCurcumin inhibits the reaction [Carbon Tetrachloride results in increased expression of HIF1A protein]23845850
C114438cyanidin 3-O-glucosidecyanidin 3-O-glucoside inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]24518827
C114438cyanidin 3-O-glucosidecyanidin 3-O-glucoside results in decreased expression of HIF1A protein24518827
D003513Cycloheximide[Cycloheximide co-treated with cobaltous chloride] results in decreased expression of HIF1A protein22537771
D003513Cycloheximide[Cycloheximide co-treated with INS protein] results in decreased expression of HIF1A protein22537771
D003513CycloheximideCycloheximide inhibits the reaction [[cobaltous chloride co-treated with Glucose] results in increased expression of HIF1A protein]25192544
D003513CycloheximideCycloheximide inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]19958256|2052403
D003513CycloheximideCycloheximide inhibits the reaction [Quercetin results in increased expression of HIF1A protein]19958256
D003513CycloheximideCycloheximide inhibits the reaction [sodium arsenite results in increased expression of HIF1A protein]11641398
D003513CycloheximideCycloheximide inhibits the reaction [sodium arsenite results in increased stability of HIF1A protein]24188932
D003513CycloheximideCycloheximide inhibits the reaction [zinc chloride results in increased expression of HIF1A protein alternative form]11739637
D003513CycloheximideCycloheximide promotes the reaction [Cobalt results in increased expression of HIF1A protein]24497960
D003513CycloheximideCycloheximide promotes the reaction [nickel chloride results in increased expression of HIF1A protein]24497960
D003513CycloheximideCycloheximide results in increased degradation of HIF1A protein11641398
D003513CycloheximideL-4F peptide promotes the reaction [[Cycloheximide co-treated with cobaltous chloride] results in decreased expression of HIF1A protein]22537771
D003513CycloheximideL-4F peptide promotes the reaction [[Cycloheximide co-treated with INS protein] results in decreased expression of HIF1A protein]22537771
D003513Cycloheximidescutellarin inhibits the reaction [[cobaltous chloride co-treated with Glucose co-treated with Cycloheximide] results in decreased expression of HIF1A protein]25192544
D003513Cycloheximidescutellarin promotes the reaction [Cycloheximide inhibits the reaction [[cobaltous chloride co-treated with Glucose] results in increased expression of HIF1A protein]]25192544
D003513CycloheximideCycloheximide inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of HIF1A protein]23593480
D003513CycloheximideCycloheximide results in decreased expression of HIF1A24221993
C000536cyclohexylisocyanate[cobaltous chloride results in increased activity of HIF1A protein] which results in decreased susceptibility to cyclohexylisocyanate14980978
D003520CyclophosphamideCyclophosphamide results in increased expression of HIF1A mRNA15331540
D016572CyclosporineCyclosporine affects the activity of HIF1A protein25596134
D016572Cyclosporine[Cyclosporine co-treated with cobaltous chloride] results in increased expression of HIF1A protein22343435
D016572CyclosporineCyclosporine inhibits the reaction [cobaltous chloride results in increased activity of HIF1A protein]16682453
D016572CyclosporineCyclosporine inhibits the reaction [HIF1A protein results in decreased uptake of Cisplatin]17066447
D016572CyclosporineCyclosporine inhibits the reaction [HIF1A protein results in decreased uptake of Fluorouracil]17066447
D016572CyclosporineCyclosporine inhibits the reaction [IGF1 protein results in increased activity of HIF1A protein]16682453
D016572CyclosporineCyclosporine inhibits the reaction [IGF1 protein results in increased expression of HIF1A protein]16682453
D016572CyclosporineCyclosporine results in decreased expression of HIF1A mRNA27989131
D016572CyclosporineCyclosporine results in increased expression of HIF1A mRNA25562108
D016572CyclosporineCyclosporine inhibits the reaction [Acetaminophen results in increased expression of HIF1A]21316383
D016572CyclosporineCyclosporine inhibits the reaction [Acetaminophen results in increased expression of HIF1A protein]16530163
D016572Cyclosporine[Cyclosporine co-treated with cobaltous chloride] results in increased expression of HIF1A protein22343435
D016572CyclosporineCyclosporine results in decreased activity of HIF1A protein17190738
D016572CyclosporineCyclosporine results in decreased expression of HIF1A17190738
D003561CytarabineCytarabine results in increased expression of HIF1A mRNA23264188
D003609DactinomycinDactinomycin inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]19958256
D003609DactinomycinDactinomycin inhibits the reaction [TNF protein results in increased expression of HIF1A protein]12479793
D003630DaunorubicinDaunorubicin results in increased expression of HIF1A mRNA23831762
D003630DaunorubicinDexrazoxane inhibits the reaction [Daunorubicin results in increased expression of HIF1A mRNA]23831762
C014347decitabinedecitabine promotes the reaction [HIF1A protein binds to STC2 promoter]18394600
C044919deferipronedeferiprone results in increased expression of HIF1A protein21558026
D003676Deferoxamine"15,16-dihydrotanshinone I inhibits the reaction [Deferoxamine results in increased expression of HIF1A protein]"26282490
D003676Deferoxamine2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Deferoxamine results in increased expression of HIF1A protein]16527254
D003676Deferoxamine3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole inhibits the reaction [Deferoxamine results in increased expression of HIF1A protein]11286986
D003676Deferoxaminearsenic trioxide promotes the reaction [Deferoxamine results in increased expression of HIF1A protein]16330433
D003676DeferoxamineCadmium inhibits the reaction [Deferoxamine results in increased expression of HIF1A protein]10866824
D003676DeferoxamineDeferoxamine promotes the reaction [[HIF1A protein binds to VEGFA promoter] which results in increased expression of VEGFA mRNA]19695866
D003676Deferoxamine[Deferoxamine results in decreased abundance of Iron] which results in increased expression of HIF1A mRNA12393473
D003676DeferoxamineDeferoxamine results in decreased degradation of HIF1A protein19695866
D003676DeferoxamineDeferoxamine results in increased expression of and results in increased stability of HIF1A protein17015263
D003676DeferoxamineDeferoxamine results in increased expression of HIF1A protein10866824|1128698
D003676DeferoxamineDeferoxamine results in increased stability of and results in increased expression of HIF1A protein17364964
D003676Deferoxamineferric citrate inhibits the reaction [Deferoxamine results in increased expression of HIF1A protein]16527254|1701526
D003676DeferoxamineN-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [Deferoxamine results in increased expression of HIF1A protein]16527254
D003676DeferoxamineTP53 gene mutant form promotes the reaction [Deferoxamine results in increased expression of HIF1A protein]16527254
D003676DeferoxamineDeferoxamine results in increased expression of HIF1A16046841
D003676Deferoxamine2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Deferoxamine results in increased expression of HIF1A protein]16527254
D003676DeferoxamineDeferoxamine affects the localization of HIF1A protein16772336
D003676Deferoxamineferric citrate inhibits the reaction [Deferoxamine results in increased expression of HIF1A protein]16527254
D003676DeferoxamineDeferoxamine results in increased activity of HIF1A protein10559391|1498097
D003676Deferoxamine[Deferoxamine results in increased activity of HIF1A protein] which results in decreased susceptibility to Carmustine14980978
D003676DeferoxamineDeferoxamine results in increased expression of HIF1A protein21558026
D003676DeferoxamineDeferoxamine results in increased stability of HIF1A protein16227210
D003676DeferoxamineDeferoxamine results in increased expression of HIF1A protein11514583|1508909
C107676deguelinbenzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [deguelin results in increased degradation of HIF1A protein]17764071
C107676deguelindeguelin inhibits the reaction [IGF1 protein results in increased expression of HIF1A protein]17764071
C107676deguelindeguelin inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]17764071|1857572
C107676deguelindeguelin metabolite inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]19139008
C107676deguelindeguelin results in increased degradation of HIF1A protein17764071
C017185delphinidindelphinidin inhibits the reaction [Hydrogen Peroxide results in increased expression of HIF1A protein]18603805
C007262deoxynivalenol[clay analog co-treated with deoxynivalenol] results in decreased expression of HIF1A mRNA23922676
C007262deoxynivalenoldeoxynivalenol results in decreased expression of HIF1A mRNA23922676
D003907DexamethasoneDexamethasone results in decreased expression of HIF1A mRNA25047013
D003907DexamethasoneDexamethasone results in increased expression of HIF1A mRNA19853017
D064730DexrazoxaneDexrazoxane inhibits the reaction [Daunorubicin results in increased expression of HIF1A mRNA]23831762
D016264Dextran SulfateDextran Sulfate results in increased expression of HIF1A protein26074695
D016264Dextran Sulfateresveratrol inhibits the reaction [Dextran Sulfate results in increased expression of HIF1A protein]26074695
C041517dibenzo(a,l)pyrene"[Benzo(a)pyrene co-treated with dibenzo(a,l)pyrene] affects the expression of HIF1A mRNA"17690111
D003994BucladesineBucladesine results in increased expression of HIF1A mRNA18591213
D003998Dicarboxylic AcidsDicarboxylic Acids results in increased expression of HIF1A protein20881034
D003999Dichloroacetic AcidDichloroacetic Acid results in decreased expression of HIF1A mRNA22705712
D002945CisplatinABCB1 affects the reaction [HIF1A affects the susceptibility to Cisplatin]21964646
D002945CisplatinABCC1 affects the reaction [HIF1A affects the susceptibility to Cisplatin]21964646
D002945CisplatinAcetylcysteine inhibits the reaction [Cisplatin affects the localization of HIF1A protein]17066447
D002945CisplatinCisplatin affects the activity of HIF1A protein25596134
D002945CisplatinCisplatin affects the localization of HIF1A protein17066447|2093547
D002945CisplatinCisplatin inhibits the reaction [cobaltous chloride results in increased activity of HIF1A protein]11090055
D002945CisplatinCisplatin inhibits the reaction [Oxygen deficiency results in increased activity of HIF1A protein]11090055
D002945CisplatinCisplatin promotes the reaction [HIF1A protein binds to VEGFA promoter]20935474
D002945CisplatinCisplatin results in decreased activity of HIF1A protein17498666
D002945CisplatinCisplatin results in decreased expression of HIF1A mRNA25450742
D002945CisplatinCisplatin results in decreased expression of HIF1A protein17498666
D002945CisplatinCisplatin results in decreased susceptibility to HIF1A protein17066447
D002945CisplatinCisplatin results in increased degradation of HIF1A protein17498666
D002945CisplatinCisplatin results in increased expression of HIF1A protein21674241
D002945CisplatinCyclosporine inhibits the reaction [HIF1A protein results in decreased uptake of Cisplatin]17066447
D002945CisplatinHIF1A affects the susceptibility to Cisplatin21964646
D002945CisplatinHIF1A protein affects the susceptibility to Cisplatin16532342
D002945CisplatinHIF1A protein results in decreased uptake of Cisplatin17066447
D002945CisplatinTopotecan inhibits the reaction [Cisplatin affects the localization of HIF1A protein]20935474
D002945CisplatinTopotecan inhibits the reaction [Cisplatin promotes the reaction [HIF1A protein binds to VEGFA promoter]]20935474
D002945CisplatinTP53 protein affects the reaction [Cisplatin results in increased degradation of HIF1A protein]17498666
D002945CisplatinCisplatin results in increased expression of HIF1A mRNA18656965
D004004DichlororibofuranosylbenzimidazoleDichlororibofuranosylbenzimidazole inhibits the reaction [TNF protein results in increased expression of HIF1A protein]12479793
D004008DiclofenacDiclofenac results in decreased expression of HIF1A protein12912967
D004041Dietary Fats[Dietary Fats co-treated with Dietary Sucrose] results in decreased expression of HIF1A mRNA27070252
D004041Dietary Fatsresveratrol inhibits the reaction [[Dietary Fats co-treated with Dietary Sucrose] results in decreased expression of HIF1A mRNA]27070252
D004041Dietary FatsDietary Fats results in increased expression of HIF1A mRNA19030233
D004041Dietary Fatsrimonabant inhibits the reaction [Dietary Fats results in increased expression of HIF1A mRNA]19030233
D019422Dietary Sucrose[Dietary Fats co-treated with Dietary Sucrose] results in decreased expression of HIF1A mRNA27070252
D019422Dietary Sucroseresveratrol inhibits the reaction [[Dietary Fats co-treated with Dietary Sucrose] results in decreased expression of HIF1A mRNA]27070252
D004052Diethylnitrosamine[cobaltous chloride co-treated with Diethylnitrosamine] results in increased expression of HIF1A protein11751435
D004052Diethylnitrosamine[Diethylnitrosamine co-treated with N-nitrosomorpholine] results in increased expression of HIF1A mRNA19383236
D004052Diethylnitrosamine[Diethylnitrosamine co-treated with N-nitrosomorpholine] results in increased expression of HIF1A protein19383236
D004077Digoxin2-(2-(4-(4-nitrobenzyloxy)phenyl)ethyl)isothiourea methanesulfonate inhibits the reaction [Digoxin affects the localization of HIF1A protein]19647009
D004077Digoxin2-(2-(4-(4-nitrobenzyloxy)phenyl)ethyl)isothiourea methanesulfonate inhibits the reaction [Digoxin results in increased phosphorylation of HIF1A protein]19647009
D004077Digoxin3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole inhibits the reaction [Digoxin affects the localization of HIF1A protein]19647009
D004077DigoxinDigoxin affects the localization of HIF1A protein19647009
D004077DigoxinDigoxin results in increased activity of HIF1A protein19647009
D004077DigoxinDigoxin results in increased phosphorylation of and results in increased expression of HIF1A protein19647009
D004077DigoxinKN 93 inhibits the reaction [Digoxin affects the localization of HIF1A protein]19647009
D004077DigoxinKN 93 inhibits the reaction [Digoxin results in increased phosphorylation of HIF1A protein]19647009
C472511dimethylarsinous aciddimethylarsinous acid results in decreased expression of HIF1A mRNA16507463
D0151279,10-Dimethyl-1,2-benzanthracene"9,10-Dimethyl-1,2-benzanthracene results in increased activity of HIF1A protein"19502547
D0151279,10-Dimethyl-1,2-benzanthracene"9,10-Dimethyl-1,2-benzanthracene results in increased expression of HIF1A mRNA"22485181
D0151279,10-Dimethyl-1,2-benzanthracene"9,10-Dimethyl-1,2-benzanthracene results in increased expression of HIF1A protein"21294050
D0151279,10-Dimethyl-1,2-benzanthracene"Quercetin inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of HIF1A protein]"21294050
D0151279,10-Dimethyl-1,2-benzanthracene"9,10-Dimethyl-1,2-benzanthracene affects the expression of HIF1A mRNA"21785161
D004121Dimethyl SulfoxideDimethyl Sulfoxide results in increased expression of HIF1A mRNA22193206
C051904dinophysistoxin 1dinophysistoxin 1 affects the expression of HIF1A mRNA28939011
C007517diphenyleneiodoniumdiphenyleneiodonium inhibits the reaction [[Arsenic results in increased abundance of Reactive Oxygen Species] which results in increased expression of HIF1A protein]21687637
C007517diphenyleneiodoniumdiphenyleneiodonium inhibits the reaction [[[Arsenic results in increased abundance of Reactive Oxygen Species] which results in increased expression of HIF1A protein] which results in increased expression of VEGFA mRNA]21687637
C007517diphenyleneiodoniumdiphenyleneiodonium inhibits the reaction [Cadmium Chloride results in increased expression of HIF1A protein]21984483
C007517diphenyleneiodoniumdiphenyleneiodonium results in decreased expression of HIF1A protein23144690
C007517diphenyleneiodoniumdiphenyleneiodonium results in increased expression of HIF1A protein12595275
D004229Dithiothreitol"Dithiothreitol inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of HIF1A protein]"17658243
D004229DithiothreitolDithiothreitol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of HIF1A protein alternative form]14695184
D0192972,4-Dinitrophenol"2,4-Dinitrophenol results in increased expression of HIF1A mRNA"15740689
D004281Docosahexaenoic AcidsDocosahexaenoic Acids results in decreased activity of HIF1A protein19528198
C119788dodecaboratedodecaborate analog inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]24270971
C119788dodecaboratedodecaborate analog results in decreased activity of HIF1A protein24270971
D004298DopamineAcetylcysteine inhibits the reaction [Dopamine results in increased expression of HIF1A protein]19410601
D004298DopamineDopamine results in increased expression of HIF1A protein19410601
D004298Dopamine[Dopamine results in increased expression of HIF1A protein] which results in increased expression of and results in increased phosphorylation of TP53 protein19410601
D004298Dopamine[Dopamine results in increased expression of HIF1A protein] which results in increased expression of BBC3 mRNA19410601
D004298Dopamine[Dopamine results in increased expression of HIF1A protein] which results in increased expression of BBC3 protein19410601
D004298Dopamine[Dopamine results in increased expression of HIF1A protein] which results in increased expression of BNIP3 mRNA19410601
D004298Dopamine[Dopamine results in increased expression of HIF1A protein] which results in increased expression of BNIP3 protein19410601
D004298Dopamine[Dopamine results in increased expression of HIF1A protein] which results in increased expression of TP53 protein19410601
D004298DopamineClodronic Acid inhibits the reaction [Dopamine results in decreased expression of HIF1A protein]25818600
D004298DopamineDopamine results in decreased expression of HIF1A protein25818600
D004298Dopamineeticlopride inhibits the reaction [Dopamine results in decreased expression of HIF1A protein]25818600
D004298Dopaminezoledronic acid inhibits the reaction [Dopamine results in decreased expression of HIF1A protein]25818600
C025034doxifluridineHIF1A protein results in decreased susceptibility to doxifluridine16734730
D004317Doxorubicincobaltous chloride inhibits the reaction [Doxorubicin promotes the reaction [HIPK2 protein binds to HIF1A promoter]]19714248
D004317DoxorubicinDoxorubicin promotes the reaction [HIPK2 protein binds to HIF1A promoter]19714248
D004317DoxorubicinDoxorubicin results in decreased activity of HIF1A protein17498666
D004317DoxorubicinDoxorubicin results in increased expression of HIF1A protein17912235
D004317DoxorubicinHIF1A protein affects the susceptibility to Doxorubicin16532342|1662808
D004317DoxorubicinNFKB1 protein affects the reaction [Doxorubicin results in increased expression of HIF1A protein]17912235
D004317Doxorubicinzinc chloride inhibits the reaction [cobaltous chloride inhibits the reaction [Doxorubicin promotes the reaction [HIPK2 protein binds to HIF1A promoter]]]19714248
D004317Doxorubicin[Doxorubicin co-treated with zinc chloride] results in decreased expression of HIF1A mRNA19714248
D004317DoxorubicinDoxorubicin results in increased expression of HIF1A protein17531194
D004317Doxorubicin[tricarbonyldichlororuthenium (II) dimer co-treated with Doxorubicin] results in increased expression of HIF1A mRNA21443895
D004365Drugs, Chinese Herbal"Drugs, Chinese Herbal results in decreased expression of HIF1A mRNA"27369806
C042986ebselenebselen inhibits the reaction [Acetylcysteine inhibits the reaction [Oxygen deficiency results in increased activity of HIF1A protein]]19374849
C042986ebselenebselen inhibits the reaction [Acetylcysteine inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A mRNA]]19374849
C042986ebselenebselen inhibits the reaction [glutathione glycylethyl ester inhibits the reaction [Oxygen deficiency results in increased activity of HIF1A protein]]19374849
C042986ebselenebselen inhibits the reaction [glutathione glycylethyl ester inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A mRNA]]19374849
D004448EchinomycinEchinomycin inhibits the reaction [cobaltous chloride results in increased activity of HIF1A protein]16772336
D004610Ellagic AcidEllagic Acid results in decreased expression of HIF1A mRNA12002526
D004642EmodinEmodin inhibits the reaction [Oxygen deficiency results in decreased expression of HIF1A mRNA]21382473
C118739entinostatentinostat results in decreased expression of HIF1A protein21041383
C118739entinostatTNFSF10 protein promotes the reaction [entinostat results in decreased expression of HIF1A protein]21041383
C045651epigallocatechin gallateepigallocatechin gallate results in decreased expression of HIF1A mRNA20346928
C045651epigallocatechin gallateepigallocatechin gallate results in decreased expression of HIF1A protein20346928
C045651epigallocatechin gallateepigallocatechin gallate results in decreased hydroxylation of and results in decreased degradation of HIF1A protein16005427
C045651epigallocatechin gallateepigallocatechin gallate results in increased expression of and results in increased activity of HIF1A protein16005427
C078846epoxomicinepoxomicin inhibits the reaction [scutellarin inhibits the reaction [[cobaltous chloride co-treated with Glucose] results in increased expression of HIF1A protein]]25192544
C078846epoxomicinepoxomicin inhibits the reaction [scutellarin results in decreased expression of HIF1A protein]25192544
C078846epoxomicinepoxomicin results in increased expression of HIF1A protein25192544
D000431EthanolEthanol results in decreased expression of HIF1A mRNA28789864
D000431Ethanol[sodium arsenite co-treated with Ethanol] affects the localization of HIF1A protein22872060
D000431EthanolEthanol results in increased expression of HIF1A mRNA27837167
D000431EthanolEthanol results in increased expression of HIF1A protein27837167
D000431EthanolNFE2L2 affects the reaction [tetramethylpyrazine inhibits the reaction [Ethanol results in increased expression of HIF1A mRNA]]27837167
D000431EthanolNFE2L2 affects the reaction [tetramethylpyrazine inhibits the reaction [Ethanol results in increased expression of HIF1A protein]]27837167
D000431Ethanoltetramethylpyrazine inhibits the reaction [Ethanol results in increased expression of HIF1A mRNA]27837167
D000431Ethanoltetramethylpyrazine inhibits the reaction [Ethanol results in increased expression of HIF1A protein]27837167
D000431EthanolEthanol affects the expression of HIF1A mRNA11772933
D000431EthanolEthanol results in increased expression of HIF1A mRNA23273579
D005031EthylenethioureaEthylenethiourea results in increased expression of HIF1A mRNA18801409
C045989eticloprideeticlopride inhibits the reaction [Dopamine results in decreased expression of HIF1A protein]25818600
D005047EtoposideHIF1A mutant form inhibits the reaction [Oxygen deficiency results in decreased susceptibility to Etoposide]23144690
D005054EugenolEugenol results in increased expression of HIF1A mRNA20713136
C010953exochelinsexochelins results in increased stability of and results in increased expression of HIF1A protein12460908
C533794EZN 2968EZN 2968 results in decreased activity of HIF1A protein21574568
C018541falcarinolfalcarinol results in increased expression of HIF1A protein19800326
C069346fascaplysinefascaplysine analog results in decreased expression of HIF1A protein28756150
D011345FenofibrateFenofibrate affects the activity of HIF1A protein25596134
D011345FenofibrateFenofibrate results in increased expression of HIF1A mRNA17118139
D011345FenofibrateFenofibrate affects the activity of HIF1A protein25596134
C025314ferric citrateferric citrate inhibits the reaction [Deferoxamine results in increased expression of HIF1A protein]16527254|1701526
C025314ferric citrateferric citrate inhibits the reaction [Quercetin results in increased expression of HIF1A mRNA]17364964
C025314ferric citrateferric citrate inhibits the reaction [Quercetin results in increased expression of HIF1A protein]17364964
C025314ferric citrateferric citrate inhibits the reaction [Deferoxamine results in increased expression of HIF1A protein]16527254
C020326ferric nitrilotriacetate"ferric nitrilotriacetate inhibits the reaction [Asbestos, Crocidolite results in increased activity of HIF1A protein]"18385176
C020326ferric nitrilotriacetateferric nitrilotriacetate inhibits the reaction [Razoxane results in increased activity of HIF1A protein]18385176
C024823ferric sulfateferric sulfate inhibits the reaction [Nickel results in increased stability of HIF1A protein]16877034
C029451ferrous chloride[benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with alpha-ketoglutaric acid co-treated with Ascorbic Acid co-treated with ferrous chloride] promotes the reaction [VHL protein binds to HIF1A protein]19263519
C029451ferrous chlorideferrous chloride inhibits the reaction [sodium arsenite results in decreased hydroxylation of HIF1A protein]24188932
C029451ferrous chlorideferrous chloride inhibits the reaction [sodium arsenite results in increased expression of HIF1A protein]24188932
C029451ferrous chloridemanganese chloride inhibits the reaction [[benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with alpha-ketoglutaric acid co-treated with Ascorbic Acid co-treated with ferrous chloride] promotes the reaction [VHL protein binds to HIF1A protein]]19263519
C029451ferrous chloride[ferrous chloride results in increased hydroxylation of EPAS1 protein] promotes the reaction [HIF1A protein binds to VHL protein]12606543
C020748ferrous sulfateferrous sulfate inhibits the reaction [Chromium results in increased expression of HIF1A protein]16386771
C020748ferrous sulfateferrous sulfate inhibits the reaction [Cobalt results in increased expression of HIF1A protein]16386771
C020748ferrous sulfateferrous sulfate inhibits the reaction [galangin results in increased expression of HIF1A protein]17973296
C020748ferrous sulfateferrous sulfate inhibits the reaction [Nickel results in increased expression of HIF1A protein]16386771
C020748ferrous sulfateferrous sulfate inhibits the reaction [Quercetin results in increased expression of HIF1A protein]17973296
D018120FinasterideFinasteride inhibits the reaction [Testosterone results in increased expression of HIF1A protein]27866977
C017875fisetinfisetin promotes the reaction [Oxygen deficiency promotes the reaction [HIF1A protein binds to EP300 protein]]20153296
C017875fisetinfisetin promotes the reaction [Oxygen deficiency results in increased expression of HIF1A protein]20153296
C017875fisetincobaltous chloride promotes the reaction [fisetin results in increased activity of HIF1A protein]25428606
C017875fisetinfisetin promotes the reaction [cobaltous chloride results in increased activity of HIF1A protein]25428606
C017875fisetinfisetin results in increased activity of HIF1A protein25428606
C017875fisetinfisetin results in increased expression of and affects the localization of HIF1A protein25428606
C017875fisetinfisetin results in increased expression of HIF1A mRNA25428606
D044950FlavanonesFlavanones inhibits the reaction [cobaltous chloride results in increased expression of HIF1A protein]25446852
D044950FlavanonesFlavanones results in decreased expression of HIF1A protein25446852
C043562flavoneflavone inhibits the reaction [Oxygen deficiency promotes the reaction [HIF1A protein binds to EP300 protein]]20153296
C024352fludarabinefludarabine results in decreased expression of HIF1A mRNA15213310
C024352fludarabinefludarabine results in decreased expression of HIF1A protein15213310
C007738fluoranthene[Benzo(a)pyrene co-treated with fluoranthene] affects the expression of HIF1A mRNA17690111
D005472FluorouracilAcetylcysteine inhibits the reaction [Fluorouracil affects the localization of HIF1A protein]17066447
D005472FluorouracilCyclosporine inhibits the reaction [HIF1A protein results in decreased uptake of Fluorouracil]17066447
D005472FluorouracilFluorouracil affects the localization of HIF1A protein17066447
D005472FluorouracilFluorouracil results in decreased expression of HIF1A protein27163855
D005472FluorouracilFluorouracil results in decreased susceptibility to HIF1A protein17066447
D005472FluorouracilHIF1A protein affects the susceptibility to Fluorouracil16628086
D005472FluorouracilHIF1A protein results in decreased uptake of Fluorouracil17066447
D005472FluorouracilHIF1A results in decreased susceptibility to Fluorouracil17219956
D005492Folic AcidFolic Acid results in decreased expression of HIF1A protein14633603
D005492Folic Acid[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of HIF1A gene20938992
C007768formononetinformononetin results in increased expression of and results in decreased degradation of HIF1A protein21309574
C007768formononetinformononetin results in increased expression of HIF1A mRNA21309574
C039281furanfuran results in increased methylation of HIF1A gene22079235
C037032galanginferrous sulfate inhibits the reaction [galangin results in increased expression of HIF1A protein]17973296
C037032galangingalangin promotes the reaction [Oxygen deficiency promotes the reaction [HIF1A protein binds to EP300 protein]]20153296
C037032galangingalangin promotes the reaction [Oxygen deficiency results in increased expression of HIF1A protein]20153296
C037032galangingalangin results in increased expression of HIF1A protein17973296
C037032galanginIron inhibits the reaction [galangin results in increased expression of HIF1A protein]17973296
D005707Gallic AcidGallic Acid results in increased expression of HIF1A mRNA23406025
D005707Gallic AcidAKT1 protein inhibits the reaction [Gallic Acid results in decreased expression of HIF1A mRNA]26530725
D005707Gallic AcidGallic Acid results in decreased expression of HIF1A mRNA26530725
D005707Gallic AcidGallic Acid results in decreased expression of HIF1A protein26530725
D005707Gallic AcidHIF1A protein inhibits the reaction [Gallic Acid results in decreased expression of VEGFA mRNA]26530725
C027235gallium nitrategallium nitrate results in decreased expression of HIF1A mRNA18586083
C001277geldanamycinbenzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [geldanamycin results in increased degradation of HIF1A protein]11980636
C001277geldanamycingeldanamycin inhibits the reaction [cobaltous chloride results in increased expression of HIF1A protein]12811834
C001277geldanamycingeldanamycin results in decreased expression of HIF1A protein14726529|1531953
C001277geldanamycingeldanamycin results in increased degradation of HIF1A protein11980636
C001277geldanamycinlactacystin inhibits the reaction [geldanamycin results in increased degradation of HIF1A protein]11980636
C056507gemcitabineHIF1A protein affects the susceptibility to gemcitabine16628086
D019833GenisteinGenistein affects the reaction [cobaltous chloride promotes the reaction [HIF1A protein binds to ARNT protein binds to EDN1 promoter]]10939628
D019833GenisteinGenistein affects the reaction [Oxygen deficiency promotes the reaction [HIF1A protein binds to ARNT protein binds to EDN1 promoter]]10939628
D019833GenisteinGenistein inhibits the reaction [S-Nitrosoglutathione results in increased expression of HIF1A protein]11514583
D019833GenisteinGenistein inhibits the reaction [TNF protein results in increased expression of HIF1A protein]11514583
D005839Gentamicins[Gentamicins co-treated with cobaltous chloride] results in increased expression of HIF1A protein23145036
D005839Gentamicins[Gentamicins co-treated with cobaltous chloride] results in increased expression of HIF1A protein23145036
D005839GentamicinsGentamicins results in decreased expression of HIF1A mRNA22061828
D005839GentamicinsGentamicins results in increased expression of HIF1A mRNA18656965|2206182
C007845gingerolgingerol inhibits the reaction [Oxygen deficiency results in decreased expression of HIF1A mRNA]21382473
D046934GinkgolidesGinkgolides results in increased expression of and results in increased activity of HIF1A protein17647269
D046934GinkgolidesGinkgolides results in increased expression of HIF1A protein17647269
D005912GliotoxinGliotoxin results in decreased expression of HIF1A mRNA20432243
D005944GlucosamineGlucosamine affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of HIF1A protein]19254699
D005944GlucosamineGlucosamine inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]19254699
D005944GlucosamineGlucosamine results in decreased expression of HIF1A mRNA22020377
D005944GlucosamineGlucosamine results in decreased expression of HIF1A protein19254699|2202037
D005947Glucosebenzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [scutellarin inhibits the reaction [[cobaltous chloride co-treated with Glucose] results in increased expression of HIF1A protein]]25192544
D005947Glucose[cobaltous chloride co-treated with Glucose] promotes the reaction [HIF1A protein binds to EP300 protein]25192544
D005947Glucose[cobaltous chloride co-treated with Glucose] results in increased expression of and results in decreased ubiquitination of HIF1A protein25192544
D005947GlucoseCycloheximide inhibits the reaction [[cobaltous chloride co-treated with Glucose] results in increased expression of HIF1A protein]25192544
D005947Glucoseepoxomicin inhibits the reaction [scutellarin inhibits the reaction [[cobaltous chloride co-treated with Glucose] results in increased expression of HIF1A protein]]25192544
D005947GlucoseMG 262 inhibits the reaction [scutellarin inhibits the reaction [[cobaltous chloride co-treated with Glucose] results in increased expression of HIF1A protein]]25192544
D005947Glucose[Oxygen co-treated with Glucose] inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of HIF1A protein]28400208
D005947Glucose[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of HIF1A protein28400208
D005947GlucoseParticulate Matter inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of HIF1A protein]28400208
D005947Glucosescutellarin inhibits the reaction [[cobaltous chloride co-treated with Glucose co-treated with Cycloheximide] results in decreased expression of HIF1A protein]25192544
D005947Glucosescutellarin inhibits the reaction [[cobaltous chloride co-treated with Glucose] promotes the reaction [HIF1A protein binds to EP300 protein]]25192544
D005947Glucosescutellarin inhibits the reaction [[cobaltous chloride co-treated with Glucose] results in increased expression of and results in decreased ubiquitination of HIF1A protein]25192544
D005947Glucosescutellarin promotes the reaction [Cycloheximide inhibits the reaction [[cobaltous chloride co-treated with Glucose] results in increased expression of HIF1A protein]]25192544
D005947GlucoseVehicle Emissions inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of HIF1A protein]28400208
D005947Glucose2-methoxyestradiol inhibits the reaction [Glucose results in increased expression of HIF1A protein]21617913
D005947Glucose3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole inhibits the reaction [Glucose results in increased expression of HIF1A protein]21617913
D005947Glucose[3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole results in decreased activity of HIF1A protein] results in decreased susceptibility to [Oxygen deficiency co-treated with Glucose deficiency]23108914
D005947Glucose[Glucose co-treated with Oxygen deficiency] inhibits the reaction [ARNT protein binds to HIF1A protein]18227068
D005947Glucose[Glucose co-treated with Oxygen deficiency] promotes the reaction [Pyruvaldehyde binds to and results in decreased activity of HIF1A protein]18227068
D005947Glucose[Glucose co-treated with SOD2 gene mutant form] results in decreased expression of HIF1A protein19429140
D005947GlucoseGlucose results in increased expression of HIF1A protein21617913
D005947Glucose[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of HIF1A mRNA23108914
D005947Glucose[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of HIF1A protein19228841|2310891
D005947Glucose[Glucose deficiency co-treated with Oxygen deficiency] results in increased expression of HIF1A protein21293012
D005947Glucose[[Glucose deficiency co-treated with Oxygen deficiency] results in increased expression of HIF1A protein] which results in increased expression of SLC8A1 mRNA21293012
D005947GlucoseGlucose results in increased expression of HIF1A mRNA26891083
D005947GlucoseGlucose results in increased expression of HIF1A protein26891083
D005947GlucoseHIF1A protein affects the reaction [Glucose results in increased expression of CTGF protein]26891083
D005947GlucoseHIF1A protein affects the reaction [Glucose results in increased expression of EDN1 protein]26891083
D005947GlucoseHIF1A protein affects the reaction [Glucose results in increased expression of FN1 protein]26891083
D005947GlucoseHIF1A protein affects the reaction [Glucose results in increased expression of TGFB1 protein]26891083
D005947GlucoseHIF1A protein affects the reaction [Glucose results in increased expression of VEGFA protein]26891083
D005947GlucoseMIR217 mRNA affects the reaction [Glucose results in increased expression of HIF1A mRNA]26891083
D005947GlucoseMIR217 mRNA affects the reaction [Glucose results in increased expression of HIF1A protein]26891083
D005947Glucose[Oxygen deficiency co-treated with Glucose deficiency co-treated with Oxygen] results in increased expression of HIF1A mRNA23421680
D005947Glucose[Oxygen deficiency co-treated with Glucose deficiency co-treated with Oxygen] results in increased expression of HIF1A protein23421680
D005947Glucoseresveratrol inhibits the reaction [Glucose results in increased expression of HIF1A mRNA]26891083
D005947Glucoseresveratrol inhibits the reaction [Glucose results in increased expression of HIF1A protein]26891083
D005947Glucoseresveratrol inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency co-treated with Oxygen] results in increased expression of HIF1A mRNA]23421680
D005947Glucoseresveratrol inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency co-treated with Oxygen] results in increased expression of HIF1A protein]23421680
D005947GlucoseSIRT1 protein affects the reaction [resveratrol inhibits the reaction [Glucose results in increased expression of HIF1A protein]]26891083
D005947GlucoseGLO1 protein inhibits the reaction [[Glucose co-treated with Oxygen deficiency] inhibits the reaction [ARNT protein binds to HIF1A protein]]18227068
D005947GlucoseGLO1 protein inhibits the reaction [[Glucose co-treated with Oxygen deficiency] inhibits the reaction [HIF1A protein binds to NOS3 promoter]]18227068
D005947GlucoseGLO1 protein inhibits the reaction [[Glucose co-treated with Oxygen deficiency] promotes the reaction [HIF1A protein binds to CXCR4 promoter]]18227068
D005947GlucoseGLO1 protein inhibits the reaction [[Glucose co-treated with Oxygen deficiency] promotes the reaction [Pyruvaldehyde binds to and results in decreased activity of HIF1A protein]]18227068
D005947Glucose[Glucose co-treated with Oxygen deficiency] inhibits the reaction [HIF1A protein binds to CXCL12 promoter]18227068
D005947Glucose[Glucose co-treated with Oxygen deficiency] inhibits the reaction [HIF1A protein binds to CXCR4 promoter]18227068
D005947Glucose[Glucose co-treated with Oxygen deficiency] inhibits the reaction [HIF1A protein binds to NOS3 promoter]18227068
D005978Glutathione"Glutathione inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of HIF1A protein]"17658243
D005978GlutathioneGlutathione inhibits the reaction [sodium arsenite results in increased expression of HIF1A protein]11641398
D005978GlutathioneGlutathione inhibits the reaction [Vanadates results in increased expression of HIF1A protein]16678800
D019803Glutathione DisulfideGlutathione Disulfide analog promotes the reaction [cobaltous chloride results in increased activity of HIF1A protein]19374849
D019803Glutathione DisulfideGlutathione Disulfide analog promotes the reaction [Oxygen deficiency results in increased activity of HIF1A protein]19374849
C077304glutathione glycylethyl ester1-(2-chloroethyl)-1-nitrosourea inhibits the reaction [glutathione glycylethyl ester inhibits the reaction [Oxygen deficiency results in increased activity of HIF1A protein]]19374849
C077304glutathione glycylethyl esterebselen inhibits the reaction [glutathione glycylethyl ester inhibits the reaction [Oxygen deficiency results in increased activity of HIF1A protein]]19374849
C077304glutathione glycylethyl esterebselen inhibits the reaction [glutathione glycylethyl ester inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A mRNA]]19374849
C077304glutathione glycylethyl esterglutathione glycylethyl ester inhibits the reaction [Oxygen deficiency results in increased activity of HIF1A protein]19374849
C077304glutathione glycylethyl esterglutathione glycylethyl ester inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A mRNA]19374849
C081021Go 6976Go 6976 inhibits the reaction [sodium arsenite results in increased expression of HIF1A mRNA]15089098
C511402Grape Seed Proanthocyanidins[Catechin co-treated with Grape Seed Proanthocyanidins] results in increased expression of HIF1A mRNA24763279
C412815GW 4064GW 4064 results in decreased expression of HIF1A mRNA26655953
D006427Hemin[Hemin results in decreased abundance of Iron] which results in increased expression of HIF1A mRNA12393473
C027492Huang QiHuang Qi results in increased expression of and results in decreased degradation of HIF1A protein21309574
C027492Huang QiHuang Qi results in increased expression of HIF1A mRNA21309574
D006834HydrazinesCadmium Chloride inhibits the reaction [[cobaltous chloride results in increased activity of HIF1A protein] which results in decreased susceptibility to Hydrazines]14980978
D006834Hydrazines[cobaltous chloride results in increased activity of HIF1A protein] which results in decreased susceptibility to Hydrazines14980978
D006854HydrocortisoneHydrocortisone results in increased expression of HIF1A mRNA23264615
D006861Hydrogen Peroxidedelphinidin inhibits the reaction [Hydrogen Peroxide results in increased expression of HIF1A protein]18603805
D006861Hydrogen PeroxideHIF1A protein affects the reaction [Hydrogen Peroxide results in decreased expression of BCL2 protein]25108166
D006861Hydrogen PeroxideHIF1A protein affects the reaction [Hydrogen Peroxide results in increased cleavage of NOTCH1 protein]25108166
D006861Hydrogen PeroxideHIF1A protein affects the reaction [Hydrogen Peroxide results in increased expression of BAX protein]25108166
D006861Hydrogen PeroxideHIF1A protein affects the reaction [Hydrogen Peroxide results in increased expression of FOXO3 protein]25108166
D006861Hydrogen PeroxideHIF1A protein affects the reaction [Hydrogen Peroxide results in increased expression of HIF1A protein]25108166
D006861Hydrogen PeroxideHIF1A protein affects the reaction [Hydrogen Peroxide results in increased expression of TP53 protein]25108166
D006861Hydrogen PeroxideHydrogen Peroxide affects the expression of HIF1A mRNA21179406
D006861Hydrogen PeroxideHydrogen Peroxide results in increased expression of HIF1A protein15297373|1860380
D006861Hydrogen PeroxideHydrogen Peroxide results in increased expression of HIF1A protein alternative form14695184
D006861Hydrogen Peroxide"N-(N-(3,5-difluorophenacetyl)alanyl)phenylglycine tert-butyl ester promotes the reaction [Hydrogen Peroxide results in increased expression of HIF1A protein]"25108166
D006861Hydrogen PeroxideQuercetin inhibits the reaction [Hydrogen Peroxide results in increased expression of HIF1A protein]25108166
D006861Hydrogen PeroxideHydrogen Peroxide results in increased expression of HIF1A mRNA16507596
D006861Hydrogen PeroxideHydrogen Peroxide results in increased expression of HIF1A protein16507596
D006861Hydrogen PeroxideAscorbic Acid inhibits the reaction [Hydrogen Peroxide results in decreased hydroxylation of HIF1A protein]20881940
D006861Hydrogen PeroxideHydrogen Peroxide results in decreased hydroxylation of HIF1A protein20881940
D006877Hydroxamic AcidsHydroxamic Acids results in decreased expression of HIF1A protein27163855
D007052IbuprofenIbuprofen affects the activity of HIF1A protein25596134
D007052IbuprofenIbuprofen results in decreased expression of HIF1A protein12912967
C492448ICG 001ICG 001 results in decreased expression of HIF1A mRNA26191083
D007069IfosfamideIfosfamide affects the activity of HIF1A protein25596134
D007200IndicanIndican inhibits the reaction [cobaltous chloride affects the localization of HIF1A protein]21863063
D015759IonomycinCurcumin analog inhibits the reaction [Ionomycin promotes the reaction [Oxygen deficiency results in increased activity of HIF1A protein]]20554536
D015759IonomycinCurcumin analog inhibits the reaction [Ionomycin results in increased activity of HIF1A protein]20554536
D015759IonomycinIonomycin promotes the reaction [Oxygen deficiency results in increased activity of HIF1A protein]20554536
D015759IonomycinIonomycin results in increased activity of HIF1A protein20554536
D007501Iron[Deferoxamine results in decreased abundance of Iron] which results in increased expression of HIF1A mRNA12393473
D007501Iron[Hemin results in decreased abundance of Iron] which results in increased expression of HIF1A mRNA12393473
D007501IronIron inhibits the reaction [galangin results in increased expression of HIF1A protein]17973296
D007501IronIron inhibits the reaction [manganese chloride results in increased expression of HIF1A protein]19263519
D007501IronIron inhibits the reaction [Nickel results in increased stability of HIF1A protein]16877034
D007501IronIron inhibits the reaction [Quercetin results in increased expression of and affects the localization of HIF1A protein]19729006
D007501IronIron inhibits the reaction [Quercetin results in increased expression of HIF1A protein]17973296
D007501Iron[Quercetin results in decreased abundance of Iron] which results in increased expression of HIF1A protein17364964
D007501IronHIF1A gene mutant form results in decreased metabolism of Iron16787915
D007501IronHIF1A protein results in increased susceptibility to Iron16787915
D007501IronIron deficiency results in decreased expression of HIF1A mRNA16629162
D007501IronIron affects the reaction [HIF1A protein affects the susceptibility to Oxygen]16899821
C036643isoeugenolisoeugenol results in increased expression of HIF1A mRNA17559653
D007545IsoproterenolIsoproterenol results in decreased expression of HIF1A mRNA20003209
D007559IvermectinIvermectin results in decreased activity of HIF1A protein26351913
C544151jinfukangjinfukang results in decreased expression of HIF1A mRNA27392435
C006552kaempferolkaempferol promotes the reaction [Oxygen deficiency promotes the reaction [HIF1A protein binds to EP300 protein]]20153296
D020910KetorolacKetorolac results in decreased expression of HIF1A protein12912967
C072105KN 93KN 93 inhibits the reaction [Digoxin affects the localization of HIF1A protein]19647009
C072105KN 93KN 93 inhibits the reaction [Digoxin results in increased phosphorylation of HIF1A protein]19647009
C072105KN 93KN 93 inhibits the reaction [Ouabain affects the localization of HIF1A protein]19647009
C072105KN 93KN 93 inhibits the reaction [Ouabain results in increased phosphorylation of HIF1A protein]19647009
C472885L-4F peptidebenzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [L-4F peptide inhibits the reaction [INS protein results in increased expression of HIF1A protein]]22537771
C472885L-4F peptideL-4F peptide inhibits the reaction [cobaltous chloride results in increased expression of HIF1A protein]22537771
C472885L-4F peptideL-4F peptide inhibits the reaction [INS protein results in increased expression of HIF1A protein]22537771
C472885L-4F peptideL-4F peptide inhibits the reaction [lysophosphatidic acid results in increased expression of HIF1A protein]22537771
C472885L-4F peptideL-4F peptide inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]22537771
C472885L-4F peptideL-4F peptide promotes the reaction [[Cycloheximide co-treated with cobaltous chloride] results in decreased expression of HIF1A protein]22537771
C472885L-4F peptideL-4F peptide promotes the reaction [[Cycloheximide co-treated with INS protein] results in decreased expression of HIF1A protein]22537771
C472885L-4F peptideL-4F peptide results in increased degradation of HIF1A protein22537771
C472885L-4F peptideL-4F peptide results in decreased expression of HIF1A protein22537771
C067713lactacystinlactacystin inhibits the reaction [geldanamycin results in increased degradation of HIF1A protein]11980636
C490728lapatiniblapatinib inhibits the reaction [bafilomycin A1 results in increased expression of HIF1A protein]25981168
C490728lapatiniblapatinib inhibits the reaction [concanamycin A results in increased expression of HIF1A protein]25981168
C045463leflunomideleflunomide results in increased expression of HIF1A mRNA28988120
C440499lipopolysaccharide, Escherichia coli O111 B4"lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of HIF1A protein"26213241
C440499lipopolysaccharide, Escherichia coli O111 B4"wogonin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of HIF1A protein]"26213241
D008070Lipopolysaccharideschetomin inhibits the reaction [HIF1A protein promotes the reaction [Lipopolysaccharides results in increased expression of VEGFA protein]]19744167
D008070LipopolysaccharidesHIF1A protein promotes the reaction [Lipopolysaccharides results in increased expression of VEGFA protein]19744167
D008070LipopolysaccharidesLipopolysaccharides results in increased expression of HIF1A mRNA20067761
D008070LipopolysaccharidesLipopolysaccharides results in increased expression of HIF1A protein19744167|2208780
D008070LipopolysaccharidesLipopolysaccharides results in increased localization of HIF1A protein22087807
D008070LipopolysaccharidesOxygen deficiency promotes the reaction [Lipopolysaccharides results in increased expression of HIF1A protein]22087807
D008070LipopolysaccharidesTLR4 affects the reaction [Lipopolysaccharides results in increased localization of HIF1A protein]22087807
D008070LipopolysaccharidesHIF1A protein promotes the reaction [Lipopolysaccharides results in increased expression of BNIP3 mRNA]21307008
D008070LipopolysaccharidesHIF1A protein promotes the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]21307008
D008070LipopolysaccharidesHIF1A protein promotes the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]21307008
D008070LipopolysaccharidesLipopolysaccharides results in increased expression of HIF1A mRNA19339665|2130700
D008070LipopolysaccharidesLipopolysaccharides results in increased expression of HIF1A protein21307008
D008070Lipopolysaccharidesmethyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of HIF1A mRNA]19339665
D008070LipopolysaccharidesPropofol inhibits the reaction [Lipopolysaccharides results in increased expression of HIF1A mRNA]21307008
D008070LipopolysaccharidesPropofol inhibits the reaction [Lipopolysaccharides results in increased expression of HIF1A protein]21307008
D047311LuteolinLuteolin inhibits the reaction [chromium hexavalent ion results in increased expression of HIF1A mRNA]25448439
D047311LuteolinLuteolin inhibits the reaction [chromium hexavalent ion results in increased expression of HIF1A protein]25448439
D047311LuteolinLuteolin inhibits the reaction [Oxygen deficiency results in increased activity of HIF1A protein]19958256
D047311LuteolinLuteolin promotes the reaction [Oxygen deficiency results in increased expression of HIF1A protein]20153296
D047311LuteolinLuteolin results in decreased activity of HIF1A protein19958256
D047311LuteolinLuteolin results in increased expression of and results in increased activity of HIF1A protein19958256
C032881lysophosphatidic acidL-4F peptide inhibits the reaction [lysophosphatidic acid results in increased expression of HIF1A protein]22537771
C032881lysophosphatidic acidlysophosphatidic acid results in increased expression of HIF1A protein17919812|2253777
C032881lysophosphatidic acid[lysophosphatidic acid results in increased expression of HIF1A protein] which results in increased expression of VEGFA mRNA17919812
C032881lysophosphatidic acid[lysophosphatidic acid results in increased expression of HIF1A protein] which results in increased expression of VEGFA protein17919812
C032881lysophosphatidic acidresveratrol inhibits the reaction [lysophosphatidic acid results in increased expression of HIF1A protein]17919812
C106335macrophage stimulatory lipopeptide 2HIF1A mRNA affects the reaction [[nickel sulfate co-treated with macrophage stimulatory lipopeptide 2] results in increased secretion of IL6 protein]20600219
C106335macrophage stimulatory lipopeptide 2HIF1A protein promotes the reaction [[macrophage stimulatory lipopeptide 2 co-treated with nickel sulfate] results in increased expression of PTGS2 mRNA]18832182
C106335macrophage stimulatory lipopeptide 2HIF1A protein promotes the reaction [[macrophage stimulatory lipopeptide 2 co-treated with nickel sulfate] results in increased expression of PTGS2 protein]18832182
C106335macrophage stimulatory lipopeptide 2HIF1A protein promotes the reaction [[macrophage stimulatory lipopeptide 2 co-treated with nickel sulfate] results in increased secretion of CXCL1 protein]18832182
C106335macrophage stimulatory lipopeptide 2HIF1A protein promotes the reaction [[macrophage stimulatory lipopeptide 2 co-treated with nickel sulfate] results in increased secretion of CXCL5 protein]18832182
C106335macrophage stimulatory lipopeptide 2HIF1A protein promotes the reaction [[macrophage stimulatory lipopeptide 2 co-treated with nickel sulfate] results in increased secretion of CXCL8 protein]18832182
C106335macrophage stimulatory lipopeptide 2HIF1A protein promotes the reaction [[macrophage stimulatory lipopeptide 2 co-treated with nickel sulfate] results in increased secretion of VEGFA protein]18832182
C106335macrophage stimulatory lipopeptide 2[macrophage stimulatory lipopeptide 2 co-treated with nickel sulfate] results in decreased expression of HIF1A mRNA18832182
C106335macrophage stimulatory lipopeptide 2macrophage stimulatory lipopeptide 2 co-treated with [nickel sulfate results in increased expression of HIF1A protein]18832182
C106335macrophage stimulatory lipopeptide 2[nickel sulfate co-treated with macrophage stimulatory lipopeptide 2] results in increased expression of HIF1A protein20600219
C106335macrophage stimulatory lipopeptide 2[U 0126 co-treated with SB 203580] inhibits the reaction [[nickel sulfate co-treated with macrophage stimulatory lipopeptide 2] results in increased expression of HIF1A protein]20600219
C106335macrophage stimulatory lipopeptide 2U 0126 inhibits the reaction [[nickel sulfate co-treated with macrophage stimulatory lipopeptide 2] results in increased expression of HIF1A protein]20600219
C030290malonic acidmalonic acid affects the expression of HIF1A protein16034640
D008345ManganeseManganese results in increased expression of and results in increased activity of HIF1A protein16386771
D008345ManganeseManganese results in increased expression of HIF1A mRNA17175027
C025340manganese chloride2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [manganese chloride results in increased expression of and results in increased activity of HIF1A protein]20152896
C025340manganese chlorideAscorbic Acid inhibits the reaction [manganese chloride results in decreased hydroxylation of HIF1A protein]19074761
C025340manganese chlorideAscorbic Acid inhibits the reaction [manganese chloride results in increased stability of HIF1A protein]19074761
C025340manganese chlorideHIF1A mutant form inhibits the reaction [manganese chloride results in increased secretion of VEGFA protein]19263519
C025340manganese chlorideIron inhibits the reaction [manganese chloride results in increased expression of HIF1A protein]19263519
C025340manganese chloridemanganese chloride inhibits the reaction [[benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with alpha-ketoglutaric acid co-treated with Ascorbic Acid co-treated with ferrous chloride] promotes the reaction [VHL protein binds to HIF1A protein]]19263519
C025340manganese chloride[manganese chloride results in decreased activity of P4HTM protein] which results in decreased degradation of HIF1A protein19263519
C025340manganese chloride[manganese chloride results in decreased activity of P4HTM protein] which results in decreased hydroxylation of HIF1A protein19263519
C025340manganese chloridemanganese chloride results in decreased degradation of HIF1A protein19263519
C025340manganese chloridemanganese chloride results in decreased hydroxylation of HIF1A protein19074761
C025340manganese chloridemanganese chloride results in increased expression of and results in increased activity of and results in increased stability of HIF1A protein20152896
C025340manganese chloridemanganese chloride results in increased expression of HIF1A mRNA17175027
C025340manganese chloridemanganese chloride results in increased expression of HIF1A protein19263519
C025340manganese chloridemanganese chloride results in increased stability of HIF1A protein19074761
C025340manganese chloridepyrazolanthrone inhibits the reaction [manganese chloride results in increased expression of and results in increased activity of and results in increased stability of HIF1A protein]20152896
C025340manganese chlorideSB 203580 inhibits the reaction [manganese chloride results in increased expression of and results in increased activity of and results in increased stability of HIF1A protein]20152896
C025340manganese chlorideSB 203580 inhibits the reaction [manganese chloride results in increased expression of and results in increased activity of HIF1A protein]20152896
C025340manganese chlorideVHL protein affects the reaction [manganese chloride results in increased expression of HIF1A protein]19263519
C025340manganese chloridemanganese chloride results in increased expression of HIF1A mRNA17467022
C025340manganese chloridemanganese chloride results in increased expression of HIF1A protein19263519
C097284manganese(III)-tetrakis(4-benzoic acid)porphyrinmanganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [Oxygen deficiency results in decreased expression of HIF1A mRNA]21382473
D008627Mercuric ChlorideMercuric Chloride inhibits the reaction [cobaltous chloride results in increased activity of HIF1A protein]11090055
D008627Mercuric ChlorideMercuric Chloride inhibits the reaction [Oxygen deficiency results in increased activity of HIF1A protein]11090055
D008627Mercuric ChlorideMercuric Chloride results in increased activity of HIF1A protein19502547
D008687MetforminMetformin affects the activity of HIF1A protein25596134
D008701MethapyrileneMethapyrilene results in decreased expression of HIF1A mRNA28903497
D008715Methionine[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of HIF1A gene20938992
D008748MethylcholanthreneMethylcholanthrene results in increased expression of HIF1A mRNA23273579
C008435methyldithiocarbamatemethyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of HIF1A mRNA]19339665
D008741Methyl MethanesulfonateMethyl Methanesulfonate results in increased expression of HIF1A mRNA23649840
D0156551-Methyl-4-phenylpyridinium1-Methyl-4-phenylpyridinium inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]12062197
D0156551-Methyl-4-phenylpyridinium1-Methyl-4-phenylpyridinium results in decreased expression of HIF1A protein20546814
D0156551-Methyl-4-phenylpyridinium1-Methyl-4-phenylpyridinium results in increased expression of HIF1A mRNA25234470|2676836
D0156551-Methyl-4-phenylpyridinium1-Methyl-4-phenylpyridinium results in increased expression of HIF1A protein26768367
D0156551-Methyl-4-phenylpyridiniumSIRT1 protein affects the reaction [1-Methyl-4-phenylpyridinium results in increased expression of HIF1A mRNA]26768367
D0156321-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine"[3,4-dihydroxybenzoate co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in increased expression of HIF1A mRNA"19679656
D0156321-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine"[Clioquinol co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in increased expression of HIF1A protein"19679656
D0156321-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine"[3,4-dihydroxybenzoate co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine metabolite] affects the localization of HIF1A protein"19679656
D0156321-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine"[salicylaldehyde isonicotinoyl hydrazone co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine metabolite] affects the localization of HIF1A protein"19679656
D008777MethyltestosteroneMethyltestosterone results in increased expression of HIF1A mRNA29191790
C423917MG 262MG 262 inhibits the reaction [scutellarin inhibits the reaction [[cobaltous chloride co-treated with Glucose] results in increased expression of HIF1A protein]]25192544
C423917MG 262MG 262 inhibits the reaction [scutellarin results in decreased expression of HIF1A protein]25192544
C423917MG 262MG 262 results in increased expression of HIF1A protein25192544
D008825MiconazoleMiconazole results in decreased expression of HIF1A mRNA22262564
D008898MimosineMimosine results in increased expression of HIF1A protein24349381
D008898MimosineMimosine results in increased activity of HIF1A protein10559391
D008898MimosineMimosine results in increased expression of HIF1A protein25469848
D008911MinocyclineMinocycline inhibits the reaction [Oxygen deficiency results in increased stability of HIF1A protein]24292262
D008911MinocyclineMinocycline promotes the reaction [HIF1A protein binds to VHL protein]24292262
D008911Minocycline[[Minocycline promotes the reaction [HIF1A protein binds to VHL protein]] co-treated with [Minocycline results in increased expression of EGLN1 protein]] inhibits the reaction [Oxygen deficiency results in increased stability of HIF1A protein]24292262
D008911Minocycline[[Minocycline promotes the reaction [HIF1A protein binds to VHL protein]] co-treated with [Minocycline results in increased expression of EGLN1 protein]] results in increased degradation of HIF1A protein24292262
D008911MinocyclineMinocycline results in increased degradation of HIF1A protein24292262
C502230Mn(III) 5,10,15,20-tetrakis(N-methylpyridinium-2-yl)porphyrin"Mn(III) 5,10,15,20-tetrakis(N-methylpyridinium-2-yl)porphyrin inhibits the reaction [cobaltous chloride results in increased expression of HIF1A protein]"21036805
C502230Mn(III) 5,10,15,20-tetrakis(N-methylpyridinium-2-yl)porphyrin"Mn(III) 5,10,15,20-tetrakis(N-methylpyridinium-2-yl)porphyrin inhibits the reaction [sodium arsenite results in increased expression of HIF1A protein]"24188932
C502230Mn(III) 5,10,15,20-tetrakis(N-methylpyridinium-2-yl)porphyrin"Mn(III) 5,10,15,20-tetrakis(N-methylpyridinium-2-yl)porphyrin inhibits the reaction [sodium arsenite results in increased stability of HIF1A protein]"24188932
C002373monobutyryl cyclic AMPCREM protein inhibits the reaction [monobutyryl cyclic AMP results in increased activity of HIF1A protein]25381014
C002373monobutyryl cyclic AMPmonobutyryl cyclic AMP results in increased expression of and affects the localization of and results in increased activity of HIF1A protein25381014
C437683motexafin gadolinium[motexafin gadolinium co-treated with Zinc Acetate] results in increased expression of HIF1A protein16357179
C437683motexafin gadoliniummotexafin gadolinium results in increased expression of HIF1A protein16357179
D009151Mustard GasMustard Gas inhibits the reaction [Oxygen deficiency results in increased expression of and results in increased stability of HIF1A protein]26082309
D009151Mustard GasQuinolones inhibits the reaction [Mustard Gas inhibits the reaction [Oxygen deficiency results in increased stability of HIF1A protein]]26082309
D009151Mustard GasMustard Gas results in increased expression of HIF1A mRNA15674843
C040015myricetinmyricetin promotes the reaction [Oxygen deficiency promotes the reaction [HIF1A protein binds to EP300 protein]]20153296
C040015myricetinmyricetin results in decreased activity of HIF1A protein19958256
C040015myricetin[myricetin results in increased activity of SIRT1 protein] which results in increased expression of HIF1A protein22245592
C040015myricetinmyricetin results in increased expression of HIF1A protein19958256|2224559
C080955N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamideN-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [Deferoxamine results in increased expression of HIF1A protein]16527254
C487056N-AcetylcysteinamideN-Acetylcysteinamide inhibits the reaction [Ovalbumin results in increased expression of HIF1A protein]18160846
D019810Sodium AzideSodium Azide affects the expression of HIF1A protein16034640
D037742Nanotubes, Carbon"Nanotubes, Carbon affects the expression of HIF1A mRNA"23845593
D037742Nanotubes, Carbon"Nanotubes, Carbon analog results in increased expression of HIF1A mRNA"25554681
D037742Nanotubes, Carbon"Nanotubes, Carbon results in increased expression of HIF1A mRNA"25554681
D0150581-Naphthylisothiocyanate1-Naphthylisothiocyanate results in decreased expression of HIF1A mRNA19181614
D0150581-NaphthylisothiocyanateNFE2L2 promotes the reaction [1-Naphthylisothiocyanate results in decreased expression of HIF1A mRNA]19181614
C552435N-ethoxymethyl-3-amino-1,2,4-benzotriazine-1,4-dioxide"N-ethoxymethyl-3-amino-1,2,4-benzotriazine-1,4-dioxide inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]"20530905
D009525NiacinNiacin results in decreased expression of HIF1A protein18549825
D009532Nickelchromium hexavalent ion inhibits the reaction [Nickel results in increased stability of and results in increased expression of HIF1A protein]19403854
D009532Nickelferric sulfate inhibits the reaction [Nickel results in increased stability of HIF1A protein]16877034
D009532Nickelferrous sulfate inhibits the reaction [Nickel results in increased expression of HIF1A protein]16386771
D009532NickelHIF1A mRNA affects the reaction [Nickel results in increased expression of KDM3A mRNA]20881000
D009532NickelHIF1A mRNA affects the reaction [Nickel results in increased expression of KDM3A protein]20881000
D009532NickelHIF1A protein promotes the reaction [Nickel results in increased expression of NDRG1 mRNA]15341671
D009532NickelHIF1A protein promotes the reaction [Nickel results in increased expression of NDRG1 protein]15341671
D009532NickelHIF1A protein promotes the reaction [Nickel results in increased expression of SERPINE1 mRNA]11504687
D009532NickelIron inhibits the reaction [Nickel results in increased stability of HIF1A protein]16877034
D009532NickelNickel affects the localization of HIF1A protein21401309
D009532Nickel[Nickel co-treated with Arsenic] results in increased expression of HIF1A protein16386771
D009532Nickel[Nickel co-treated with Chromium] results in increased expression of HIF1A protein16386771
D009532NickelNickel results in decreased expression of HIF1A mRNA11504687
D009532NickelNickel results in increased expression of and results in decreased degradation of HIF1A protein11504687
D009532NickelNickel results in increased stability of and results in increased expression of and results in increased activity of HIF1A protein16386771
D009532NickelNickel results in increased stability of and results in increased expression of HIF1A protein19403854
D009532NickelNickel results in increased stability of HIF1A protein16877034
D009532NickelSTAT1 protein affects the reaction [chromium hexavalent ion inhibits the reaction [Nickel results in increased stability of and results in increased expression of HIF1A protein]]19403854
D009532NickelU 0126 inhibits the reaction [Nickel results in increased expression of HIF1A protein]11504687
D009532NickelHIF1A affects the susceptibility to Nickel20881000
D009532Nickel2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [PDGFB protein promotes the reaction [Nickel analog results in increased expression of HIF1A protein]]22700867
D009532NickelAcetylcysteine inhibits the reaction [Nickel analog results in increased expression of HIF1A protein]22700867
D009532NickelAcetylcysteine inhibits the reaction [PDGFB protein promotes the reaction [Nickel analog results in increased expression of HIF1A protein]]22700867
D009532NickelNickel analog results in increased expression of HIF1A protein22700867
D009532NickelPDGFB protein promotes the reaction [Nickel analog results in increased expression of HIF1A protein]22700867
D009532NickelNickel results in increased activity of [ARNT protein binds to HIF1A protein]11739637
C022838nickel chloride"1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt inhibits the reaction [nickel chloride results in increased expression of HIF1A protein]"22648416
C022838nickel chlorideAcetylcysteine inhibits the reaction [nickel chloride results in increased expression of HIF1A protein]22648416
C022838nickel chlorideCycloheximide promotes the reaction [nickel chloride results in increased expression of HIF1A protein]24497960
C022838nickel chlorideHIF1A mutant form inhibits the reaction [nickel chloride results in decreased expression of CDH1 protein]22648416
C022838nickel chlorideHIF1A mutant form inhibits the reaction [nickel chloride results in increased expression of FN1 protein]22648416
C022838nickel chlorideHIF1A protein affects the reaction [nickel chloride results in increased secretion of IL6 protein]17312168
C022838nickel chlorideHIF1A protein promotes the reaction [nickel chloride results in increased expression of BNIP3 protein]28552779
C022838nickel chlorideHIF1A protein promotes the reaction [nickel chloride results in increased expression of CA9 protein]28552779
C022838nickel chlorideHIF1A protein promotes the reaction [nickel chloride results in increased expression of CDKN1A protein]28552779
C022838nickel chlorideHIF1A protein promotes the reaction [nickel chloride results in increased expression of CDKN1B protein]28552779
C022838nickel chloride[nickel chloride co-treated with Tretinoin] results in increased expression of HIF1A protein25614230
C022838nickel chloridenickel chloride inhibits the reaction [VHL protein binds to HIF1A protein]16649251
C022838nickel chloridenickel chloride promotes the reaction [HIF1A protein binds to CDH1 promoter]22648416
C022838nickel chloridenickel chloride results in increased expression of and affects the localization of HIF1A protein17312168
C022838nickel chloridenickel chloride results in increased expression of and results in increased stability of HIF1A protein24497960
C022838nickel chloridenickel chloride results in increased expression of HIF1A protein10646848|1879291
C022838nickel chloridenickel chloride results in increased stability of and affects the localization of HIF1A protein21828359
C022838nickel chloridenickel chloride results in increased stability of and results in increased expression of HIF1A protein16649251
C022838nickel chloridenickel chloride results in increased stability of HIF1A protein23566959
C022838nickel chlorideRotenone inhibits the reaction [nickel chloride results in increased expression of HIF1A protein]22648416
C022838nickel chlorideAKT1 protein affects the reaction [nickel chloride results in increased expression of HIF1A protein]14729612
C022838nickel chlorideHIF1A affects the reaction [nickel chloride results in increased expression of AK4 mRNA]12729255
C022838nickel chlorideHIF1A affects the reaction [nickel chloride results in increased expression of ALDOA mRNA]12426141
C022838nickel chlorideHIF1A affects the reaction [nickel chloride results in increased expression of ARNT mRNA]12729255
C022838nickel chlorideHIF1A affects the reaction [nickel chloride results in increased expression of BNIP3 mRNA]12426141|1272925
C022838nickel chlorideHIF1A affects the reaction [nickel chloride results in increased expression of CCNG2 mRNA]12729255
C022838nickel chlorideHIF1A affects the reaction [nickel chloride results in increased expression of E2F1 mRNA]12729255
C022838nickel chlorideHIF1A affects the reaction [nickel chloride results in increased expression of EGLN1 mRNA]12729255
C022838nickel chlorideHIF1A affects the reaction [nickel chloride results in increased expression of ERO1L mRNA]12729255
C022838nickel chlorideHIF1A affects the reaction [nickel chloride results in increased expression of GAPDH mRNA]12426141
C022838nickel chlorideHIF1A affects the reaction [nickel chloride results in increased expression of GPI1 mRNA]12426141|1272925
C022838nickel chlorideHIF1A affects the reaction [nickel chloride results in increased expression of GPR137B mRNA]12729255
C022838nickel chlorideHIF1A affects the reaction [nickel chloride results in increased expression of HK2 mRNA]12426141|1272925
C022838nickel chlorideHIF1A affects the reaction [nickel chloride results in increased expression of IER3 mRNA]12729255
C022838nickel chlorideHIF1A affects the reaction [nickel chloride results in increased expression of LDHA mRNA]12426141|1272925
C022838nickel chlorideHIF1A affects the reaction [nickel chloride results in increased expression of MKNK1 mRNA]12729255
C022838nickel chlorideHIF1A affects the reaction [nickel chloride results in increased expression of NDRG1 mRNA]12729255
C022838nickel chlorideHIF1A affects the reaction [nickel chloride results in increased expression of P4HA2 mRNA]12426141|1272925
C022838nickel chlorideHIF1A affects the reaction [nickel chloride results in increased expression of PFKL mRNA]12426141|1272925
C022838nickel chlorideHIF1A affects the reaction [nickel chloride results in increased expression of PGK1 mRNA]12426141
C022838nickel chlorideHIF1A affects the reaction [nickel chloride results in increased expression of PKM mRNA]12426141|1272925
C022838nickel chlorideHIF1A affects the reaction [nickel chloride results in increased expression of PTK2 mRNA]12729255
C022838nickel chlorideHIF1A affects the reaction [nickel chloride results in increased expression of SLC2A1 mRNA]12426141|1272925
C022838nickel chlorideHIF1A affects the reaction [nickel chloride results in increased expression of TPI1 mRNA]12426141|1272925
C022838nickel chlorideHIF1A protein affects the reaction [nickel chloride results in increased expression of GAPDH mRNA]10646848
C022838nickel chlorideHIF1A protein affects the reaction [nickel chloride results in increased expression of GBE1 mRNA]15094311
C022838nickel chlorideHIF1A protein affects the reaction [nickel chloride results in increased expression of NDRG1 mRNA]10646848
C022838nickel chlorideHIF1A protein affects the susceptibility to nickel chloride12839937
C022838nickel chloridenickel chloride results in increased expression of HIF1A protein14729612|2457708
C022838nickel chloridenickel chloride results in increased expression of HIF1A16705796
C028007nickel monoxidenickel monoxide results in increased stability of and affects the localization of HIF1A protein21828359
C017557nickel subsulfidenickel subsulfide results in increased expression of HIF1A protein11978798
C017557nickel subsulfideAKT1 protein affects the reaction [nickel subsulfide results in increased expression of HIF1A protein]14729612
C017557nickel subsulfidenickel subsulfide results in increased expression of HIF1A protein14729612
C029938nickel sulfateAscorbic Acid inhibits the reaction [nickel sulfate results in decreased hydroxylation of HIF1A protein]19074761
C029938nickel sulfateAscorbic Acid inhibits the reaction [nickel sulfate results in increased expression of HIF1A protein]16288478
C029938nickel sulfateAscorbic Acid inhibits the reaction [nickel sulfate results in increased stability of HIF1A protein]17382205
C029938nickel sulfate[chromium hexavalent ion co-treated with nickel sulfate] results in increased expression of HIF1A protein17382205
C029938nickel sulfateDinoprostone promotes the reaction [nickel sulfate results in increased expression of and results in increased activity of HIF1A protein]23526216
C029938nickel sulfateHIF1A mRNA affects the reaction [[nickel sulfate co-treated with macrophage stimulatory lipopeptide 2] results in increased secretion of IL6 protein]20600219
C029938nickel sulfate[HIF1A mRNA co-treated with EPAS1 mRNA] affects the reaction [nickel sulfate results in decreased expression of USP28 protein]20046830
C029938nickel sulfate[HIF1A mRNA co-treated with EPAS1 mRNA] affects the reaction [nickel sulfate results in increased degradation of MYC protein]20046830
C029938nickel sulfateHIF1A protein promotes the reaction [[macrophage stimulatory lipopeptide 2 co-treated with nickel sulfate] results in increased expression of PTGS2 mRNA]18832182
C029938nickel sulfateHIF1A protein promotes the reaction [[macrophage stimulatory lipopeptide 2 co-treated with nickel sulfate] results in increased expression of PTGS2 protein]18832182
C029938nickel sulfateHIF1A protein promotes the reaction [[macrophage stimulatory lipopeptide 2 co-treated with nickel sulfate] results in increased secretion of CXCL1 protein]18832182
C029938nickel sulfateHIF1A protein promotes the reaction [[macrophage stimulatory lipopeptide 2 co-treated with nickel sulfate] results in increased secretion of CXCL5 protein]18832182
C029938nickel sulfateHIF1A protein promotes the reaction [[macrophage stimulatory lipopeptide 2 co-treated with nickel sulfate] results in increased secretion of CXCL8 protein]18832182
C029938nickel sulfateHIF1A protein promotes the reaction [[macrophage stimulatory lipopeptide 2 co-treated with nickel sulfate] results in increased secretion of VEGFA protein]18832182
C029938nickel sulfateHIF1A protein promotes the reaction [[nickel sulfate co-treated with Dinoprostone] results in increased secretion of CXCL8 protein]23526216
C029938nickel sulfate[macrophage stimulatory lipopeptide 2 co-treated with nickel sulfate] results in decreased expression of HIF1A mRNA18832182
C029938nickel sulfatemacrophage stimulatory lipopeptide 2 co-treated with [nickel sulfate results in increased expression of HIF1A protein]18832182
C029938nickel sulfatenickel sulfate affects the localization of and results in increased stability of HIF1A protein17382205
C029938nickel sulfate[nickel sulfate co-treated with Dinoprostone] results in increased expression of HIF1A protein18832182|2352621
C029938nickel sulfate[nickel sulfate co-treated with macrophage stimulatory lipopeptide 2] results in increased expression of HIF1A protein20600219
C029938nickel sulfatenickel sulfate promotes the reaction [Oxygen deficiency results in increased expression of HIF1A protein]23568779
C029938nickel sulfatenickel sulfate results in decreased expression of HIF1A mRNA18832182
C029938nickel sulfatenickel sulfate results in decreased hydroxylation of HIF1A protein19074761
C029938nickel sulfatenickel sulfate results in increased expression of and results in increased activity of HIF1A protein23526216
C029938nickel sulfatenickel sulfate results in increased expression of HIF1A mRNA16314067
C029938nickel sulfatenickel sulfate results in increased expression of HIF1A protein16288478|1883218
C029938nickel sulfatenickel sulfate results in increased stability of HIF1A protein19074761
C029938nickel sulfate[potassium chromate(VI) co-treated with nickel sulfate] results in increased expression of HIF1A protein17382205
C029938nickel sulfateSB 203580 inhibits the reaction [[nickel sulfate co-treated with Dinoprostone] results in increased expression of HIF1A protein]23526216
C029938nickel sulfateSB 203580 inhibits the reaction [nickel sulfate results in increased expression of HIF1A protein]23526216
C029938nickel sulfate[U 0126 co-treated with SB 203580] inhibits the reaction [[nickel sulfate co-treated with macrophage stimulatory lipopeptide 2] results in increased expression of HIF1A protein]20600219
C029938nickel sulfateU 0126 inhibits the reaction [[nickel sulfate co-treated with macrophage stimulatory lipopeptide 2] results in increased expression of HIF1A protein]20600219
C017558nickel sulfidenickel sulfide results in increased expression of HIF1A protein18792914
D009538NicotineCHRNA5 mutant form inhibits the reaction [Nicotine results in increased expression of HIF1A protein]24793809
D009538NicotineNicotine results in increased expression of HIF1A protein24793809
D009538NicotineNicotine results in decreased expression of HIF1A mRNA22687363
D009538Nicotineresveratrol inhibits the reaction [Nicotine results in decreased expression of HIF1A mRNA]22687363
D009569Nitric OxideNitric Oxide results in decreased stability of and results in decreased expression of HIF1A protein16310922
D009569Nitric OxideU 0126 inhibits the reaction [Nitric Oxide results in decreased degradation of and results in increased activity of HIF1A protein]18424783
D020030Nitric Oxide DonorsNitric Oxide Donors results in decreased expression of HIF1A protein20110409
D009582NitrofurantoinNitrofurantoin results in increased activity of HIF1A protein11841787
D009599NitroprussideNitroprusside inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]11286986
D009599NitroprussideNitroprusside results in decreased activity of HIF1A protein15465035
D009599NitroprussideNitroprusside results in decreased expression of HIF1A mRNA15465035
D009599NitroprussideNitroprusside results in decreased expression of HIF1A protein15465035
C014707nitrosobenzylmethylaminenitrosobenzylmethylamine results in increased expression of HIF1A mRNA17616710
D026422S-NitrosoglutathioneS-Nitrosoglutathione results in increased expression of HIF1A mRNA11514583
D026422S-Nitrosoglutathione"2,3-dimethoxy-1,4-naphthoquinone inhibits the reaction [S-Nitrosoglutathione results in increased expression of HIF1A protein]"11514583
D026422S-NitrosoglutathioneAKT1 protein mutant form inhibits the reaction [S-Nitrosoglutathione results in increased expression of HIF1A protein]11514583
D026422S-NitrosoglutathioneGenistein inhibits the reaction [S-Nitrosoglutathione results in increased expression of HIF1A protein]11514583
D026422S-NitrosoglutathionePIK3R1 protein mutant form inhibits the reaction [S-Nitrosoglutathione results in increased expression of HIF1A protein]11514583
D026422S-NitrosoglutathioneS-Nitrosoglutathione results in increased expression of HIF1A protein11514583
D026422S-Nitrosoglutathionewortmannin inhibits the reaction [S-Nitrosoglutathione results in increased expression of HIF1A protein]11514583
C419410N-(N-(3,5-difluorophenacetyl)alanyl)phenylglycine tert-butyl ester"N-(N-(3,5-difluorophenacetyl)alanyl)phenylglycine tert-butyl ester promotes the reaction [Hydrogen Peroxide results in increased expression of HIF1A protein]"25108166
C002741N-nitrosomorpholine[Diethylnitrosamine co-treated with N-nitrosomorpholine] results in increased expression of HIF1A mRNA19383236
C002741N-nitrosomorpholine[Diethylnitrosamine co-treated with N-nitrosomorpholine] results in increased expression of HIF1A protein19383236
C044387N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine"N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [HIF1A protein binds to CREBBP protein]"16579968
C044387N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine"N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased ubiquitination of and results in increased expression of HIF1A protein"16579968
C044387N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine"N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of HIF1A protein"16973622
C044387N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine"N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased stability of and results in increased expression of HIF1A protein"16579968
C044387N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine"zinc chloride inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased stability of and results in increased expression of HIF1A protein]"16579968
C044387N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine"Zinc inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased stability of and results in increased expression of HIF1A protein]"16579968
C464745norisoboldinenorisoboldine inhibits the reaction [TNFSF11 protein promotes the reaction [HIF1A protein binds to AHR protein]]26221077
D009665NoscapineNoscapine results in increased degradation of and results in decreased expression of and results in decreased activity of HIF1A protein16596621
C025589ochratoxin Aochratoxin A results in increased expression of HIF1A mRNA12700408|2335814
C025589ochratoxin Aochratoxin A affects the localization of HIF1A protein21554934
D019319Okadaic AcidOkadaic Acid results in increased expression of HIF1A mRNA28939011
D009840OligomycinsOligomycins results in decreased expression of HIF1A protein15840558
D010047OvalbuminN-Acetylcysteinamide inhibits the reaction [Ovalbumin results in increased expression of HIF1A protein]18160846
D010047OvalbuminOvalbumin results in increased expression of HIF1A protein18160846
C030110oxaliplatin[oxaliplatin co-treated with Topotecan] results in increased expression of HIF1A mRNA25729387
C029341oxophenylarsineoxophenylarsine results in increased expression of HIF1A protein11514583
D010100OxygenOxygen deficiency results in decreased expression of HIF1A mRNA23028566
D010100OxygenHIF1A protein promotes the reaction [Oxygen deficiency results in increased expression of VEGFA mRNA]21729202
D010100OxygenOxygen deficiency results in increased expression of HIF1A mRNA21106446
D010100Oxygencobaltous chloride inhibits the reaction [Oxygen results in increased degradation of HIF1A protein]15967517
D010100OxygenOxygen results in increased degradation of HIF1A protein15967517
D010100OxygenOxygen deficiency results in increased expression of HIF1A mRNA11401503|1499191
D010100OxygenTetrachlorodibenzodioxin inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A mRNA]14991911
D010100Oxygen1-(2-chloroethyl)-1-nitrosourea inhibits the reaction [Acetylcysteine inhibits the reaction [Oxygen deficiency results in increased activity of HIF1A protein]]19374849
D010100Oxygen1-(2-chloroethyl)-1-nitrosourea inhibits the reaction [glutathione glycylethyl ester inhibits the reaction [Oxygen deficiency results in increased activity of HIF1A protein]]19374849
D010100Oxygen"15,16-dihydrotanshinone I inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Oxygen deficiency results in increased expression of HIF1A protein]]"26282490
D010100Oxygen17-(dimethylaminoethylamino)-17-demethoxygeldanamycin inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]27899277
D010100Oxygen"1-cyclopropyl-4-(4-((5-methyl-3-(3-(4-(trifluoromethoxy)phenyl)-1,2,4-oxadiazol-5-yl)-1H-pyrazol-1-yl)methyl)pyridin-2-yl)piperazine inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]"24403227
D010100Oxygen1-Methyl-4-phenylpyridinium inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]12062197
D010100Oxygen2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Oxygen deficiency results in increased activity of HIF1A protein]19808899
D010100Oxygen2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A mRNA]11424089|1892413
D010100Oxygen2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]17307335|1980889
D010100Oxygen"3-(4-bromophenyl)-2-(ethylsulfonyl)-6-methylquinoxaline-1,4-dioxide inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Oxygen deficiency results in increased expression of HIF1A protein]]"20524035
D010100Oxygen"3-(4-bromophenyl)-2-(ethylsulfonyl)-6-methylquinoxaline-1,4-dioxide inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]"20524035
D010100Oxygen"3,5-dihydroxy-4'-methoxystilbene inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]"24975222
D010100Oxygen3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole inhibits the reaction [HIF1A protein promotes the reaction [Oxygen deficiency results in increased expression of CD36 mRNA]]19640849
D010100Oxygen3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole inhibits the reaction [HIF1A protein promotes the reaction [Oxygen deficiency results in increased expression of CD36 protein]]19640849
D010100Oxygen3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]11286986
D010100Oxygen4'-O-methylalpinumisoflavone inhibits the reaction [Oxygen deficiency results in increased activity of HIF1A protein]19091749
D010100Oxygen4'-O-methylalpinumisoflavone inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]19091749
D010100Oxygen"6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [Cadmium inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]]"10866824
D010100Oxygenacetovanillone inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]23144690
D010100OxygenAcetylcysteine inhibits the reaction [Cadmium inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]]10866824
D010100OxygenAcetylcysteine inhibits the reaction [Oxygen deficiency results in increased activity of HIF1A protein]19374849
D010100OxygenAcetylcysteine inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A mRNA]19374849
D010100Oxygen[AKT1 protein affects the reaction [Sulindac analog results in decreased expression of HIF1A protein]] which affects the susceptibility to Oxygen18924134
D010100Oxygenalpinumisoflavone inhibits the reaction [Oxygen deficiency results in increased activity of HIF1A protein]19091749
D010100OxygenAmphotericin B inhibits the reaction [Oxygen deficiency promotes the reaction [HIF1A protein binds to EP300 protein]]16189267
D010100Oxygen[amurensin G results in decreased activity of SIRT1 protein] inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]22245592
D010100Oxygenannonacin inhibits the reaction [Oxygen deficiency results in increased expression of and affects the localization of HIF1A protein]20423107
D010100OxygenApigenin inhibits the reaction [Oxygen deficiency promotes the reaction [HIF1A protein binds to EP300 protein]]20153296
D010100OxygenApigenin inhibits the reaction [Oxygen deficiency results in increased activity of HIF1A protein]19958256
D010100Oxygenbenzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [resveratrol inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]]24975222
D010100Oxygenbenzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Oxygen deficiency results in increased expression of HIF1A protein]20524035|2055453
D010100Oxygenbetulin analog inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]26540049
D010100OxygenCadmium Chloride inhibits the reaction [Oxygen deficiency results in increased activity of HIF1A protein]11090055
D010100OxygenCadmium inhibits the reaction [Oxygen deficiency promotes the reaction [HIF1A protein binds to EPO promoter]]10866824
D010100OxygenCadmium inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]10866824
D010100OxygenCGB3 protein promotes the reaction [Oxygen deficiency results in increased expression of HIF1A mRNA]18591213
D010100Oxygenchetomin inhibits the reaction [HIF1A protein promotes the reaction [TNF protein results in decreased metabolism of Oxygen]]19744167
D010100OxygenCisplatin inhibits the reaction [Oxygen deficiency results in increased activity of HIF1A protein]11090055
D010100Oxygen[cobaltous chloride results in decreased abundance of Oxygen] which results in increased expression of HIF1A mRNA22269387|2332641
D010100Oxygen[cobaltous chloride results in decreased abundance of Oxygen] which results in increased expression of HIF1A protein22269387
D010100Oxygen[Curcumin analog co-treated with Sirolimus] inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]20554536
D010100Oxygen[Curcumin analog co-treated with terpestacin] inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]20554536
D010100Oxygen[Curcumin analog co-treated with vorinostat] inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]20554536
D010100OxygenCurcumin analog inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Oxygen deficiency results in increased expression of HIF1A protein]]20554536
D010100OxygenCurcumin analog inhibits the reaction [Ionomycin promotes the reaction [Oxygen deficiency results in increased activity of HIF1A protein]]20554536
D010100OxygenCurcumin analog inhibits the reaction [Oxygen deficiency results in increased expression of and results in increased activity of HIF1A protein]20554536
D010100Oxygencyanidin 3-O-glucoside inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]24518827
D010100OxygenCycloheximide inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]19958256|2052403
D010100OxygenDactinomycin inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]19958256
D010100Oxygendeguelin inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]17764071|1857572
D010100Oxygendeguelin metabolite inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]19139008
D010100Oxygendodecaborate analog inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]24270971
D010100Oxygenebselen inhibits the reaction [Acetylcysteine inhibits the reaction [Oxygen deficiency results in increased activity of HIF1A protein]]19374849
D010100Oxygenebselen inhibits the reaction [Acetylcysteine inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A mRNA]]19374849
D010100Oxygenebselen inhibits the reaction [glutathione glycylethyl ester inhibits the reaction [Oxygen deficiency results in increased activity of HIF1A protein]]19374849
D010100Oxygenebselen inhibits the reaction [glutathione glycylethyl ester inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A mRNA]]19374849
D010100Oxygenfisetin promotes the reaction [Oxygen deficiency promotes the reaction [HIF1A protein binds to EP300 protein]]20153296
D010100Oxygenfisetin promotes the reaction [Oxygen deficiency results in increased expression of HIF1A protein]20153296
D010100Oxygenflavone inhibits the reaction [Oxygen deficiency promotes the reaction [HIF1A protein binds to EP300 protein]]20153296
D010100Oxygengalangin promotes the reaction [Oxygen deficiency promotes the reaction [HIF1A protein binds to EP300 protein]]20153296
D010100Oxygengalangin promotes the reaction [Oxygen deficiency results in increased expression of HIF1A protein]20153296
D010100OxygenGenistein affects the reaction [Oxygen deficiency promotes the reaction [HIF1A protein binds to ARNT protein binds to EDN1 promoter]]10939628
D010100OxygenGlucosamine inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]19254699
D010100OxygenGlutathione Disulfide analog promotes the reaction [Oxygen deficiency results in increased activity of HIF1A protein]19374849
D010100Oxygenglutathione glycylethyl ester inhibits the reaction [Oxygen deficiency results in increased activity of HIF1A protein]19374849
D010100Oxygenglutathione glycylethyl ester inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A mRNA]19374849
D010100OxygenHIF1A affects the reaction [Oxygen deficiency affects the expression of BIRC5 mRNA]16628086
D010100OxygenHIF1A affects the reaction [Oxygen deficiency affects the expression of BIRC5 protein]16628086
D010100OxygenHIF1A gene mutant form inhibits the reaction [Oxygen deficiency results in decreased expression of CPT1A mRNA]24503013
D010100OxygenHIF1A gene mutant form inhibits the reaction [Oxygen deficiency results in decreased expression of FASN mRNA]24503013
D010100OxygenHIF1A gene mutant form inhibits the reaction [Oxygen deficiency results in decreased expression of PPARGC1A protein]24503013
D010100OxygenHIF1A gene mutant form inhibits the reaction [Oxygen deficiency results in decreased expression of SCD mRNA]24503013
D010100OxygenHIF1A gene mutant form inhibits the reaction [Oxygen deficiency results in decreased expression of SREBF1 protein]24503013
D010100Oxygen[HIF1A mRNA co-treated with EPAS1 mRNA] affects the reaction [Oxygen deficiency results in decreased expression of USP28 protein]20046830
D010100Oxygen[HIF1A mRNA co-treated with EPAS1 mRNA] affects the reaction [Oxygen deficiency results in increased degradation of MYC protein]20046830
D010100OxygenHIF1A mRNA promotes the reaction [Oxygen deficiency results in increased expression of CA9 mRNA]25351418
D010100OxygenHIF1A mRNA promotes the reaction [Oxygen deficiency results in increased expression of SLC31A1 mRNA]24614111
D010100OxygenHIF1A mutant form inhibits the reaction [Oxygen deficiency results in decreased susceptibility to Etoposide]23144690
D010100OxygenHIF1A mutant form inhibits the reaction [Oxygen deficiency results in increased expression of CBR1 protein]24975222
D010100OxygenHIF1A mutant form inhibits the reaction [Oxygen deficiency results in increased expression of NEK8 protein]25451921
D010100OxygenHIF1A mutant form inhibits the reaction [Oxygen deficiency results in increased expression of P4HA1 mRNA]23423382
D010100OxygenHIF1A mutant form inhibits the reaction [Oxygen deficiency results in increased expression of P4HA2 mRNA]23423382
D010100OxygenHIF1A mutant form inhibits the reaction [Oxygen deficiency results in increased expression of PLOD2 mRNA]23423382
D010100OxygenHIF1A mutant form inhibits the reaction [Oxygen deficiency results in increased expression of SLC51A mRNA]24703425
D010100OxygenHIF1A protein affects the reaction [Oxygen deficiency results in increased expression of BACE1 mRNA]19196431
D010100OxygenHIF1A protein affects the reaction [Oxygen deficiency results in increased expression of BACE1 protein]19196431
D010100OxygenHIF1A protein affects the reaction [Oxygen deficiency results in increased expression of CDKN1A mRNA]19958256
D010100OxygenHIF1A protein affects the reaction [Oxygen deficiency results in increased expression of CDKN1A protein]19958256
D010100OxygenHIF1A protein affects the reaction [Oxygen deficiency results in increased expression of ENTPD1 protein]27899277
D010100OxygenHIF1A protein affects the reaction [Oxygen deficiency results in increased expression of NT5E protein]27899277
D010100OxygenHIF1A protein affects the reaction [Oxygen deficiency results in increased expression of PGK1 mRNA]23958427
D010100OxygenHIF1A protein affects the reaction [Oxygen deficiency results in increased expression of SLC2A1 protein]17442736
D010100OxygenHIF1A protein affects the reaction [Oxygen deficiency results in increased expression of SLC2A3 protein]17442736
D010100OxygenHIF1A protein affects the reaction [Oxygen deficiency results in increased secretion of COL1A1 protein]23423382
D010100OxygenHIF1A protein alternative form inhibits the reaction [Oxygen deficiency affects the localization of ARNT protein]11739637
D010100Oxygen[HIF1A protein alternative form inhibits the reaction [Oxygen deficiency affects the localization of ARNT protein]] promotes the reaction [HIF1A protein alternative form binds to ARNT protein]11739637
D010100OxygenHIF1A protein alternative form inhibits the reaction [Oxygen deficiency results in increased expression of ALDOA mRNA]11739637
D010100OxygenHIF1A protein alternative form inhibits the reaction [Oxygen deficiency results in increased expression of LDHA mRNA]11739637
D010100OxygenHIF1A protein alternative form inhibits the reaction [Oxygen deficiency results in increased expression of SERPINH1 mRNA]11739637
D010100OxygenHIF1A protein alternative form inhibits the reaction [Oxygen deficiency results in increased expression of VEGFA mRNA]11739637
D010100OxygenHIF1A protein promotes the reaction [Oxygen deficiency results in decreased expression of CDH1 mRNA]22340517
D010100OxygenHIF1A protein promotes the reaction [Oxygen deficiency results in decreased expression of MMP2 mRNA]22340517
D010100OxygenHIF1A protein promotes the reaction [Oxygen deficiency results in increased expression of CA9 mRNA]20042640
D010100OxygenHIF1A protein promotes the reaction [Oxygen deficiency results in increased expression of CD36 mRNA]19640849
D010100OxygenHIF1A protein promotes the reaction [Oxygen deficiency results in increased expression of CD36 protein]19640849
D010100OxygenHIF1A protein promotes the reaction [Oxygen deficiency results in increased expression of IGFBP3 mRNA]20042640
D010100OxygenHIF1A protein promotes the reaction [Oxygen deficiency results in increased expression of NDRG1 mRNA]15341671
D010100OxygenHIF1A protein promotes the reaction [Oxygen deficiency results in increased expression of NDRG1 protein]15341671
D010100OxygenHIF1A protein promotes the reaction [[Oxygen deficiency results in increased expression of PTGES protein] which results in increased chemical synthesis of Dinoprostone]20042640
D010100OxygenHIF1A protein promotes the reaction [Oxygen deficiency results in increased expression of PTGS2 mRNA]20042640
D010100OxygenHIF1A protein promotes the reaction [Oxygen deficiency results in increased expression of SNAI1 protein]22340517
D010100OxygenHIF1A protein promotes the reaction [Oxygen deficiency results in increased expression of STC2 mRNA]18394600
D010100OxygenHIF1A protein promotes the reaction [Oxygen deficiency results in increased expression of VEGFA mRNA]20524035
D010100OxygenHIF1A protein promotes the reaction [Oxygen deficiency results in increased expression of VEGFA protein]20524035
D010100OxygenHIF1A protein promotes the reaction [TNF protein results in decreased metabolism of Oxygen]19744167
D010100OxygenIonomycin promotes the reaction [Oxygen deficiency results in increased activity of HIF1A protein]20554536
D010100Oxygenkaempferol promotes the reaction [Oxygen deficiency promotes the reaction [HIF1A protein binds to EP300 protein]]20153296
D010100OxygenKDR protein affects the reaction [Oxygen deficiency results in increased expression of HIF1A protein]23144690
D010100OxygenL-4F peptide inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]22537771
D010100OxygenLuteolin inhibits the reaction [Oxygen deficiency results in increased activity of HIF1A protein]19958256
D010100OxygenLuteolin promotes the reaction [Oxygen deficiency results in increased expression of HIF1A protein]20153296
D010100OxygenMercuric Chloride inhibits the reaction [Oxygen deficiency results in increased activity of HIF1A protein]11090055
D010100OxygenMinocycline inhibits the reaction [Oxygen deficiency results in increased stability of HIF1A protein]24292262
D010100Oxygen[[Minocycline promotes the reaction [HIF1A protein binds to VHL protein]] co-treated with [Minocycline results in increased expression of EGLN1 protein]] inhibits the reaction [Oxygen deficiency results in increased stability of HIF1A protein]24292262
D010100OxygenMustard Gas inhibits the reaction [Oxygen deficiency results in increased expression of and results in increased stability of HIF1A protein]26082309
D010100Oxygenmyricetin promotes the reaction [Oxygen deficiency promotes the reaction [HIF1A protein binds to EP300 protein]]20153296
D010100Oxygen"N-ethoxymethyl-3-amino-1,2,4-benzotriazine-1,4-dioxide inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]"20530905
D010100Oxygennickel sulfate promotes the reaction [Oxygen deficiency results in increased expression of HIF1A protein]23568779
D010100OxygenNitroprusside inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]11286986
D010100OxygenOxygen affects the degradation of HIF1A protein19384570
D010100Oxygen[Oxygen co-treated with Glucose] inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of HIF1A protein]28400208
D010100OxygenOxygen deficiency affects the activity of HIF1A protein25596134
D010100OxygenOxygen deficiency affects the localization of HIF1A protein11739637|1574122
D010100Oxygen[Oxygen deficiency co-treated with arsenic trioxide] results in increased expression of HIF1A protein19825857
D010100Oxygen[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of HIF1A protein28400208
D010100Oxygen[Oxygen deficiency co-treated with Tetrachlorodibenzodioxin] results in decreased stability of HIF1A protein18072750
D010100OxygenOxygen deficiency promotes the reaction [HIF1A mutant form results in decreased expression of BCL2]24860939
D010100OxygenOxygen deficiency promotes the reaction [HIF1A mutant form results in increased activity of CASP3 protein]24860939
D010100OxygenOxygen deficiency promotes the reaction [HIF1A mutant form results in increased activity of CASP9 protein]24860939
D010100OxygenOxygen deficiency promotes the reaction [HIF1A mutant form results in increased expression of BAX]24860939
D010100OxygenOxygen deficiency promotes the reaction [HIF1A protein binds to ARNT protein binds to EDN1 promoter]10939628
D010100OxygenOxygen deficiency promotes the reaction [[HIF1A protein binds to ARNT protein] which binds to EPO enhancer]16189267
D010100OxygenOxygen deficiency promotes the reaction [[HIF1A protein binds to CD36 promoter] which results in increased expression of CD36 mRNA]19640849
D010100OxygenOxygen deficiency promotes the reaction [HIF1A protein binds to ECE1 intron]25469848
D010100OxygenOxygen deficiency promotes the reaction [HIF1A protein binds to ECE1 promoter]25469848
D010100OxygenOxygen deficiency promotes the reaction [HIF1A protein binds to EP300 protein]16189267|2015329
D010100OxygenOxygen deficiency promotes the reaction [HIF1A protein binds to EPO promoter]10866824
D010100OxygenOxygen deficiency promotes the reaction [HIF1A protein binds to GPR68 promoter]28174749
D010100OxygenOxygen deficiency promotes the reaction [HIF1A protein binds to NMBR promoter]24349381
D010100OxygenOxygen deficiency promotes the reaction [[HIF1A protein binds to NMBR promoter] which results in increased expression of NMBR mRNA]24349381
D010100OxygenOxygen deficiency promotes the reaction [HIF1A protein binds to SORL1 promoter]23486467
D010100OxygenOxygen deficiency promotes the reaction [HIF1A protein binds to VEGFA promoter]19695866
D010100OxygenOxygen deficiency promotes the reaction [HIF1A protein results in increased expression of PFKFB4 mRNA]16025159
D010100OxygenOxygen deficiency promotes the reaction [Lipopolysaccharides results in increased expression of HIF1A protein]22087807
D010100OxygenOxygen deficiency promotes the reaction [SIRT1 protein binds to HIF1A protein]22245592
D010100OxygenOxygen deficiency results in decreased degradation of HIF1A protein12376345|2004264
D010100OxygenOxygen deficiency results in decreased expression of HIF1A mRNA20862257|2651600
D010100OxygenOxygen deficiency results in increased activity of HIF1A protein11090055|1560427
D010100OxygenOxygen deficiency results in increased expression of and affects the localization of HIF1A protein20423107
D010100OxygenOxygen deficiency results in increased expression of and results in increased activity of HIF1A protein12054621|2055453
D010100OxygenOxygen deficiency results in increased expression of and results in increased localization of and results in increased activity of HIF1A protein19808899
D010100OxygenOxygen deficiency results in increased expression of and results in increased secretion of HIF1A protein22652775
D010100OxygenOxygen deficiency results in increased expression of and results in increased stability of HIF1A protein26082309
D010100OxygenOxygen deficiency results in increased expression of HIF1A mRNA11424089|1767120
D010100OxygenOxygen deficiency results in increased expression of HIF1A protein10646848|1086682
D010100Oxygen[Oxygen deficiency results in increased expression of HIF1A protein] which affects the expression of BAX protein20206160
D010100Oxygen[Oxygen deficiency results in increased expression of HIF1A protein] which results in increased expression of SORL1 protein23486467
D010100OxygenOxygen deficiency results in increased stability of and results in increased expression of HIF1A protein24236059
D010100OxygenOxygen deficiency results in increased stability of HIF1A protein11641398|1574122
D010100OxygenOxygen inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]22363556
D010100OxygenOxygen inhibits the reaction [Oxygen deficiency results in increased stability of HIF1A protein]11641398
D010100OxygenOxygen results in increased degradation of HIF1A protein19587783
D010100OxygenParticulate Matter inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of HIF1A protein]28400208
D010100Oxygenpeoniflorin inhibits the reaction [[cobaltous chloride results in decreased abundance of Oxygen] which results in increased expression of HIF1A mRNA]22269387
D010100Oxygenpeoniflorin inhibits the reaction [[cobaltous chloride results in decreased abundance of Oxygen] which results in increased expression of HIF1A protein]22269387
D010100Oxygenpeptide 5F inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]22537771
D010100Oxygenphenylmethylpyrazolone inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A mRNA]17889387
D010100Oxygenphenylmethylpyrazolone inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]17889387
D010100OxygenPhytochemicals inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A mRNA]26054451
D010100OxygenPIK3R1 protein promotes the reaction [Oxygen deficiency results in increased expression of HIF1A mRNA]19640849
D010100OxygenPIK3R1 protein promotes the reaction [Oxygen deficiency results in increased expression of HIF1A protein]19640849
D010100Oxygen[Polyphenols co-treated with Oxygen deficiency] promotes the reaction [VHL protein results in increased degradation of HIF1A protein]22279137
D010100Oxygen[Polyphenols co-treated with Oxygen deficiency] results in decreased stability of HIF1A protein22279137
D010100OxygenPolyphenols inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]22279137
D010100Oxygen[Polyphenols inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]] which results in decreased expression of VEGFA22279137
D010100OxygenPRKCD protein promotes the reaction [Oxygen deficiency results in increased expression of HIF1A mRNA]11424089
D010100Oxygen[Propolis co-treated with Oxygen deficiency] promotes the reaction [VHL protein results in increased degradation of HIF1A protein]22279137
D010100Oxygen[Propolis co-treated with Oxygen deficiency] results in decreased stability of HIF1A protein22279137
D010100OxygenPropolis inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]22279137
D010100Oxygen[Propolis inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]] which results in decreased expression of VEGFA22279137
D010100OxygenPTEN protein inhibits the reaction [Oxygen deficiency results in increased activity of HIF1A protein]19808899
D010100OxygenPTEN protein inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A mRNA]19808899
D010100OxygenPTGES protein promotes the reaction [Oxygen deficiency results in increased expression of HIF1A mRNA]20042640
D010100OxygenPTGES protein promotes the reaction [Oxygen deficiency results in increased expression of HIF1A protein]20042640
D010100OxygenQuercetin inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A mRNA]11424089
D010100OxygenQuercetin promotes the reaction [Oxygen deficiency promotes the reaction [HIF1A protein binds to EP300 protein]]20153296
D010100OxygenQuercetin promotes the reaction [Oxygen deficiency results in increased expression of HIF1A protein]20153296
D010100OxygenQuinolones inhibits the reaction [Mustard Gas inhibits the reaction [Oxygen deficiency results in increased stability of HIF1A protein]]26082309
D010100OxygenQuinolones promotes the reaction [Oxygen deficiency results in increased expression of HIF1A protein]26082309
D010100Oxygenresveratrol inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Oxygen deficiency results in increased expression of HIF1A protein]]24975222
D010100Oxygenresveratrol inhibits the reaction [Oxygen deficiency affects the localization of HIF1A protein]25297617
D010100Oxygenresveratrol inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]18674879|2015329
D010100Oxygenrosiglitazone inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A mRNA]21926265
D010100OxygenRotenone inhibits the reaction [Oxygen deficiency results in decreased degradation of HIF1A protein]12376345
D010100OxygenRotenone inhibits the reaction [Oxygen deficiency results in increased activity of HIF1A protein]19091749|1954249
D010100OxygenRotenone inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]12062197|1909174
D010100OxygenSB 203580 inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]13679210
D010100Oxygenshikonin inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]28684144
D010100OxygenSirolimus inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A mRNA]19640849
D010100OxygenSirolimus inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]17968710
D010100OxygenSIRT1 protein affects the reaction [Oxygen deficiency results in increased expression of HIF1A protein]22245592
D010100OxygenTetradecanoylphorbol Acetate inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A mRNA]11424089
D010100Oxygen[Thymidine co-treated with TYMP co-treated with Oxygen deficiency] results in increased expression of HIF1A protein15841086
D010100OxygenVEGFA protein affects the reaction [Oxygen deficiency results in increased expression of HIF1A protein]23144690
D010100OxygenVehicle Emissions inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of HIF1A protein]28400208
D010100Oxygenwortmannin inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A mRNA]11424089|1964084
D010100Oxygenwortmannin inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]20153296
D010100Oxygenzinc chloride inhibits the reaction [Oxygen deficiency results in increased activity of HIF1A protein]11090055
D010100Oxygenzinc chloride inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]19714248
D010100Oxygen[3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole results in decreased activity of HIF1A protein] results in decreased susceptibility to [Oxygen deficiency co-treated with Glucose deficiency]23108914
D010100Oxygen[baysilon results in increased abundance of Oxygen] which results in decreased expression of HIF1A mRNA29156398
D010100Oxygen[baysilon results in increased abundance of Oxygen] which results in decreased expression of HIF1A protein29156398
D010100OxygenEmodin inhibits the reaction [Oxygen deficiency results in decreased expression of HIF1A mRNA]21382473
D010100Oxygengingerol inhibits the reaction [Oxygen deficiency results in decreased expression of HIF1A mRNA]21382473
D010100Oxygen[Glucose co-treated with Oxygen deficiency] inhibits the reaction [ARNT protein binds to HIF1A protein]18227068
D010100Oxygen[Glucose co-treated with Oxygen deficiency] promotes the reaction [Pyruvaldehyde binds to and results in decreased activity of HIF1A protein]18227068
D010100OxygenHIF1A affects the susceptibility to Oxygen deficiency20881000
D010100OxygenHIF1A gene mutant form inhibits the reaction [Oxygen deficiency results in increased secretion of APLN protein]17878221
D010100OxygenHIF1A protein affects the reaction [Oxygen deficiency results in increased expression of GAPDH mRNA]10646848
D010100OxygenHIF1A protein affects the reaction [Oxygen deficiency results in increased expression of NDRG1 mRNA]10646848
D010100OxygenHIF1A protein affects the reaction [Oxygen deficiency results in increased expression of SLC2A1 mRNA]24639359
D010100OxygenHIF1A protein affects the reaction [Oxygen deficiency results in increased expression of VEGFA mRNA]24639359
D010100OxygenHIF1A protein promotes the reaction [Oxygen deficiency results in increased expression of CCR1 mRNA]20880076
D010100OxygenHIF1A protein promotes the reaction [Oxygen deficiency results in increased expression of CCR5 mRNA]20880076
D010100OxygenHIF1A protein promotes the reaction [Oxygen deficiency results in increased expression of IL13RA1 mRNA]20880076
D010100OxygenHIF1A protein promotes the reaction [Oxygen deficiency results in increased expression of MIF mRNA]20880076
D010100OxygenHIF1A protein promotes the reaction [Oxygen deficiency results in increased expression of P4HA2 mRNA]20880076
D010100OxygenHIF1A protein promotes the reaction [Oxygen deficiency results in increased expression of PGF mRNA]20880076
D010100OxygenHIF1A protein promotes the reaction [Oxygen deficiency results in increased expression of SLC37A4 mRNA]19074414
D010100OxygenHIF1A protein promotes the reaction [Oxygen deficiency results in increased expression of VEGFA mRNA]19074414|2088007
D010100Oxygenmanganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [Oxygen deficiency results in decreased expression of HIF1A mRNA]21382473
D010100OxygenOxygen deficiency affects the localization of and results in increased activity of HIF1A protein20880076
D010100OxygenOxygen deficiency affects the localization of HIF1A protein17878221|2061621
D010100Oxygen[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of HIF1A mRNA23108914
D010100Oxygen[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of HIF1A protein19228841|2310891
D010100OxygenOxygen deficiency promotes the reaction [HIF1A protein binds to MTF1 promoter]22087877
D010100OxygenOxygen deficiency promotes the reaction [[HIF1A protein binds to SLC37A4 promoter] which results in increased expression of SLC37A4 mRNA]19074414
D010100OxygenOxygen deficiency results in decreased expression of HIF1A mRNA21382473
D010100OxygenOxygen deficiency results in increased activity of and affects the localization of HIF1A protein20412331
D010100OxygenOxygen deficiency results in increased expression of HIF1A mRNA19074414|2192626
D010100OxygenOxygen deficiency results in increased expression of HIF1A protein16507596|1681474
D010100OxygenOxygen results in decreased expression of HIF1A28734801
D010100Oxygenrosiglitazone inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A mRNA]21926265
D010100Oxygen"4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]"15913578
D010100OxygenAG 1879 inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]15913578
D010100OxygenCadmium Chloride inhibits the reaction [Oxygen deficiency affects the localization of HIF1A protein]15967517
D010100Oxygencobaltous chloride promotes the reaction [Oxygen deficiency results in increased expression of HIF1A protein]15967517
D010100OxygenOxygen deficiency affects the localization of HIF1A protein15967517
D010100OxygenOxygen deficiency results in increased expression of HIF1A protein15913578|1596751
D010100OxygenRotenone inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]15913578
D010100OxygenBenzo(a)pyrene inhibits the reaction [Oxygen deficiency results in increased activity of HIF1A protein]19539049
D010100Oxygenbenzo(k)fluoranthene promotes the reaction [Oxygen deficiency results in increased activity of HIF1A protein]19539049
D010100OxygenOxygen deficiency results in increased activity of HIF1A protein19539049
D010100Oxygen[Glucose deficiency co-treated with Oxygen deficiency] results in increased expression of HIF1A protein21293012
D010100Oxygen[[Glucose deficiency co-treated with Oxygen deficiency] results in increased expression of HIF1A protein] which results in increased expression of SLC8A1 mRNA21293012
D010100OxygenHIF1A protein promotes the reaction [Oxygen deficiency results in increased expression of SLC8A1 protein]21293012
D010100OxygenHIF1A protein promotes the reaction [Oxygen deficiency results in increased expression of TUFT1 mRNA]20658530
D010100Oxygen[Oxygen deficiency co-treated with Glucose deficiency co-treated with Oxygen] results in increased expression of HIF1A mRNA23421680
D010100Oxygen[Oxygen deficiency co-treated with Glucose deficiency co-treated with Oxygen] results in increased expression of HIF1A protein23421680
D010100OxygenOxygen deficiency results in increased expression of and results in increased activity of HIF1A protein19278353
D010100OxygenOxygen deficiency results in increased expression of HIF1A mRNA12595275|2065853
D010100OxygenOxygen deficiency results in increased expression of HIF1A protein12595275|1552558
D010100OxygenOxygen deficiency results in increased stability of HIF1A protein19324842|2088194
D010100Oxygenresveratrol inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency co-treated with Oxygen] results in increased expression of HIF1A mRNA]23421680
D010100Oxygenresveratrol inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency co-treated with Oxygen] results in increased expression of HIF1A protein]23421680
D010100Oxygenresveratrol inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A mRNA]21914476
D010100OxygenVitamin K 3 inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]12595275
D010100Oxygen[Xanthine co-treated with XDH protein] inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]12595275
D010100Oxygen[ARNT protein binds to HIF1A protein] which affects the susceptibility to Oxygen deficiency22387692
D010100OxygenEGLN1 protein affects the reaction [HIF1A protein affects the susceptibility to Oxygen]16899821
D010100OxygenGLO1 protein inhibits the reaction [[Glucose co-treated with Oxygen deficiency] inhibits the reaction [ARNT protein binds to HIF1A protein]]18227068
D010100OxygenGLO1 protein inhibits the reaction [[Glucose co-treated with Oxygen deficiency] inhibits the reaction [HIF1A protein binds to NOS3 promoter]]18227068
D010100OxygenGLO1 protein inhibits the reaction [[Glucose co-treated with Oxygen deficiency] promotes the reaction [HIF1A protein binds to CXCR4 promoter]]18227068
D010100OxygenGLO1 protein inhibits the reaction [[Glucose co-treated with Oxygen deficiency] promotes the reaction [Pyruvaldehyde binds to and results in decreased activity of HIF1A protein]]18227068
D010100Oxygen[Glucose co-treated with Oxygen deficiency] inhibits the reaction [HIF1A protein binds to CXCL12 promoter]18227068
D010100Oxygen[Glucose co-treated with Oxygen deficiency] inhibits the reaction [HIF1A protein binds to CXCR4 promoter]18227068
D010100Oxygen[Glucose co-treated with Oxygen deficiency] inhibits the reaction [HIF1A protein binds to NOS3 promoter]18227068
D010100OxygenHIF1A affects the reaction [Oxygen deficiency results in increased expression of EPO mRNA]10866824
D010100OxygenHIF1A affects the reaction [Oxygen deficiency results in increased expression of NDRG1 mRNA]10910041
D010100OxygenHIF1A mutant form inhibits the reaction [Oxygen deficiency results in increased expression of CBR1 mRNA]24975222
D010100OxygenHIF1A mutant form inhibits the reaction [Oxygen deficiency results in increased expression of CBR1 protein]24975222
D010100OxygenHIF1A protein affects the reaction [Oxygen deficiency results in increased expression of CXCL12]18227068
D010100OxygenHIF1A protein affects the reaction [Oxygen deficiency results in increased expression of DDIT4 mRNA]17307335
D010100OxygenHIF1A protein affects the susceptibility to Oxygen16899821
D010100OxygenHIF1A protein affects the susceptibility to Oxygen deficiency18227068|1953904
D010100OxygenIron affects the reaction [HIF1A protein affects the susceptibility to Oxygen]16899821
D010100Oxygen[Oxygen deficiency affects the localization of ARNT protein] promotes the reaction [ARNT protein binds to HIF1A protein]11739637
D010100Oxygen[Oxygen deficiency affects the localization of ARNT protein] results in increased activity of [ARNT protein binds to HIF1A protein]11739637
D010100OxygenOxygen deficiency affects the localization of HIF1A protein24128854
D010100OxygenOxygen deficiency promotes the reaction [ARNT protein binds to HIF1A protein]11739637
D010100OxygenOxygen deficiency results in decreased ubiquitination of and results in decreased degradation of HIF1A protein12054621
D010100OxygenOxygen deficiency results in increased activity of [ARNT protein binds to HIF1A protein]11739637
D010100OxygenOxygen deficiency results in increased expression of and affects the localization of HIF1A protein19263519
D010100Oxygen[Oxygen deficiency results in increased expression of and affects the localization of HIF1A protein] promotes the reaction [HIF1A protein binds to ARNT protein]19263519
D010100OxygenOxygen deficiency results in increased expression of HIF1A protein12606543|1926351
D010100OxygenOxygen deficiency results in increased stability of and results in increased expression of HIF1A10939628
D010100OxygenOxygen results in increased hydroxylation of and results in increased degradation of HIF1A protein17382205
D010100OxygenOxygen results in increased hydroxylation of HIF1A protein15741220
D010100Oxygen[Oxygen results in increased hydroxylation of HIF1A protein] promotes the reaction [HIF1A protein modified form binds to VHL protein]15741220
D010100Oxygen[[Oxygen results in increased hydroxylation of HIF1A protein] promotes the reaction [HIF1A protein modified form binds to VHL protein]] which results in increased degradation of HIF1A15741220
D010100Oxygenprotoporphyrin IX inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]23624237
D010269ParaquatHIF1A protein affects the reaction [Paraquat results in decreased expression of TJP1 protein]26781174
D010269ParaquatHIF1A protein affects the reaction [Paraquat results in increased expression of ACTA2 protein]26781174
D010269ParaquatParaquat results in increased expression of HIF1A protein26781174
D010269ParaquatHIF1A protein affects the reaction [Paraquat results in decreased expression of TJP1 protein]26781174
D010269ParaquatHIF1A protein affects the reaction [Paraquat results in increased expression of ACTA2 protein]26781174
D010269ParaquatParaquat results in increased expression of HIF1A mRNA26781174
D010269ParaquatParaquat results in increased expression of HIF1A protein26781174
D052638Particulate MatterParticulate Matter inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of HIF1A protein]28400208
D052638Particulate MatterParticulate Matter results in decreased expression of HIF1A mRNA28412507
D052638Particulate MatterParticulate Matter results in increased expression of HIF1A mRNA19683567
D052638Particulate MatterParticulate Matter results in increased expression of HIF1A mRNA21708214
D052638Particulate MatterParticulate Matter results in decreased expression of HIF1A protein23887904
D052638Particulate MatterParticulate Matter results in increased expression of HIF1A mRNA24216475
C410127PCB 180"[2,4,4'-trichlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,3',4,4',5-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in increased expression of HIF1A mRNA"15808785
D010416PentachlorophenolPentachlorophenol results in increased expression of HIF1A mRNA23892564
C015423peoniflorinpeoniflorin inhibits the reaction [[cobaltous chloride results in decreased abundance of Oxygen] which results in increased expression of HIF1A mRNA]22269387
C015423peoniflorinpeoniflorin inhibits the reaction [[cobaltous chloride results in decreased abundance of Oxygen] which results in increased expression of HIF1A protein]22269387
C431648peptide 5Fpeptide 5F inhibits the reaction [cobaltous chloride results in increased expression of HIF1A protein]22537771
C431648peptide 5Fpeptide 5F inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]22537771
C494474perchlorateperchlorate results in increased expression of HIF1A mRNA18801409
C011272perfosfamideperfosfamide results in increased expression of HIF1A mRNA19429390
C011272perfosfamideperfosfamide results in increased expression of HIF1A protein19429390|2325165
D037342Pertussis ToxinPertussis Toxin inhibits the reaction [[Dinoprostone binds to and results in increased activity of PTGER1 protein] which results in increased expression of HIF1A protein]20335389
D037342Pertussis ToxinPertussis Toxin inhibits the reaction [sulprostone results in increased expression of HIF1A protein]20335389
D010578PetroleumPetroleum results in increased expression of HIF1A mRNA25208076
D015232Dinoprostonebenzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [[Dinoprostone binds to and results in increased activity of PTGER1 protein] which results in increased expression of HIF1A protein]20335389
D015232Dinoprostone[Dinoprostone binds to and results in increased activity of PTGER1 protein] which results in increased expression of HIF1A protein20335389
D015232DinoprostoneDinoprostone promotes the reaction [nickel sulfate results in increased expression of and results in increased activity of HIF1A protein]23526216
D015232DinoprostoneHIF1A protein promotes the reaction [[nickel sulfate co-treated with Dinoprostone] results in increased secretion of CXCL8 protein]23526216
D015232DinoprostoneHIF1A protein promotes the reaction [[Oxygen deficiency results in increased expression of PTGES protein] which results in increased chemical synthesis of Dinoprostone]20042640
D015232Dinoprostone[nickel sulfate co-treated with Dinoprostone] results in increased expression of HIF1A protein18832182|2352621
D015232DinoprostonePertussis Toxin inhibits the reaction [[Dinoprostone binds to and results in increased activity of PTGER1 protein] which results in increased expression of HIF1A protein]20335389
D015232DinoprostoneSB 203580 inhibits the reaction [[nickel sulfate co-treated with Dinoprostone] results in increased expression of HIF1A protein]23526216
D015232DinoprostoneSirolimus inhibits the reaction [[Dinoprostone binds to and results in increased activity of PTGER1 protein] which results in increased expression of HIF1A protein]20335389
D015232Dinoprostonewortmannin inhibits the reaction [[Dinoprostone binds to and results in increased activity of PTGER1 protein] which results in increased expression of HIF1A protein]20335389
D015232DinoprostoneDinoprostone inhibits the reaction [Bleomycin results in increased expression of HIF1A mRNA]28434932
D015232DinoprostoneHIF1A protein affects the reaction [Dinoprostone inhibits the reaction [Bleomycin results in increased expression of TGFB3 mRNA]]28434932
D015232Dinoprostone[HIF1A protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of CTGF mRNA]28434932
D015232Dinoprostone[HIF1A protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFB1 mRNA]28434932
D015232Dinoprostone[HIF1A protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFB2 mRNA]28434932
D015232Dinoprostone[HIF1A protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFBR1 mRNA]28434932
D015232Dinoprostone[HIF1A protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFBR2 mRNA]28434932
D010629PhenforminPhenformin results in increased expression of HIF1A protein26768367
D010634PhenobarbitalPhenobarbital results in increased expression of and results in increased activity of HIF1A protein23528251
D010634PhenobarbitalPhenobarbital inhibits the reaction [NR1I3 protein binds to HIF1A protein]23528251
D010634PhenobarbitalPhenobarbital results in increased expression of HIF1A mRNA23273579
C005435phenylmethylpyrazolonephenylmethylpyrazolone inhibits the reaction [HIF1A protein binds to VEGFA promoter]17889387
C005435phenylmethylpyrazolone[phenylmethylpyrazolone inhibits the reaction [HIF1A protein binds to VEGFA promoter]] which affects the expression of VEGFA mRNA17889387
C005435phenylmethylpyrazolonephenylmethylpyrazolone inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A mRNA]17889387
C005435phenylmethylpyrazolonephenylmethylpyrazolone inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]17889387
C018637phoronephorone results in increased activity of HIF1A protein11841787
D064209PhytochemicalsPhytochemicals inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A mRNA]26054451
C522973PI103PI103 results in decreased phosphorylation of HIF1A protein21994956
D010862PilocarpinePilocarpine results in increased expression of HIF1A mRNA17166730
C004479pimagedinepimagedine inhibits the reaction [titanium dioxide results in increased expression of HIF1A protein]25406100
C006253pirinixic acid[pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of HIF1A mRNA19710929
C006253pirinixic acidpirinixic acid results in increased expression of HIF1A mRNA17118139|1742611
D010936Plant ExtractsPlant Extracts results in decreased expression of HIF1A protein20670616|2395596
C013649plastochromanol 8plastochromanol 8 inhibits the reaction [cobaltous chloride results in increased expression of HIF1A protein]20452389
C013649plastochromanol 8plastochromanol 8 results in decreased expression of HIF1A protein20452389
C013649plastochromanol 8plastochromanol 8 results in decreased expression of HIF1A protein22050707
C013649plastochromanol 8[resveratrol co-treated with plastochromanol 8] results in decreased expression of HIF1A protein22050707
C063471polyethylene glycol-superoxide dismutasepolyethylene glycol-superoxide dismutase results in increased expression of HIF1A protein12595275
C060540polyhexamethyleneguanidinepolyhexamethyleneguanidine results in increased expression of HIF1A mRNA24583197
D059808Polyphenols[Polyphenols co-treated with Oxygen deficiency] promotes the reaction [VHL protein results in increased degradation of HIF1A protein]22279137
D059808Polyphenols[Polyphenols co-treated with Oxygen deficiency] results in decreased stability of HIF1A protein22279137
D059808PolyphenolsPolyphenols inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]22279137
D059808Polyphenols[Polyphenols inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]] which results in decreased expression of VEGFA22279137
D059808Polyphenols[[Polyphenols results in decreased expression of CDC42 protein] which results in increased expression of VHL protein] which results in increased degradation of HIF1A protein22279137
D059808PolyphenolsPolyphenols results in decreased expression of HIF1A protein22279137
C027373potassium chromate(VI)Ascorbic Acid inhibits the reaction [potassium chromate(VI) results in increased stability of HIF1A protein]17382205
C027373potassium chromate(VI)[potassium chromate(VI) co-treated with nickel sulfate] results in increased expression of HIF1A protein17382205
C027373potassium chromate(VI)potassium chromate(VI) results in increased expression of and affects the localization of HIF1A protein17382205
C027373potassium chromate(VI)potassium chromate(VI) results in increased stability of HIF1A protein17382205
D011192Potassium Dichromate4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [Potassium Dichromate results in increased expression of HIF1A protein]12213806
D011192Potassium DichromatePotassium Dichromate results in increased expression of HIF1A protein12213806
D011241PrednisonePrednisone results in increased activity of HIF1A protein19502547
D011374ProgesteroneEstradiol inhibits the reaction [Progesterone results in increased expression of HIF1A mRNA]17275223
D011374ProgesteroneProgesterone results in increased expression of HIF1A mRNA17275223
D011374ProgesteroneProgesterone results in increased expression of HIF1A15845616
D011374ProgesteroneProgesterone results in increased expression of HIF1A mRNA19690047
D064800Prolyl-Hydroxylase InhibitorsProlyl-Hydroxylase Inhibitors results in increased stability of and results in increased activity of HIF1A protein24244340
D011398PromethazinePromethazine results in decreased expression of HIF1A mRNA28903497
D015742PropofolPropofol inhibits the reaction [Lipopolysaccharides results in increased expression of HIF1A mRNA]21307008
D015742PropofolPropofol inhibits the reaction [Lipopolysaccharides results in increased expression of HIF1A protein]21307008
D011429Propolis[Propolis co-treated with Oxygen deficiency] promotes the reaction [VHL protein results in increased degradation of HIF1A protein]22279137
D011429Propolis[Propolis co-treated with Oxygen deficiency] results in decreased stability of HIF1A protein22279137
D011429PropolisPropolis inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]22279137
D011429Propolis[Propolis inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]] which results in decreased expression of VEGFA22279137
D011429Propolis[[Propolis results in decreased expression of CDC42 protein] which results in increased expression of VHL protein] which results in increased degradation of HIF1A protein22279137
D011429PropolisPropolis results in decreased expression of HIF1A protein22279137
D011435Propyl GallatePropyl Gallate results in decreased degradation of HIF1A protein17056012
D011435Propyl GallatePropyl Gallate results in increased expression of HIF1A protein17056012
C009091protocatechuic acidprotocatechuic acid results in increased stability of HIF1A protein16227210
C028025protoporphyrin IXAdenosine Triphosphate inhibits the reaction [protoporphyrin IX results in decreased activity of HIF1A protein]23624237
C028025protoporphyrin IXprotoporphyrin IX affects the localization of HIF1A protein23624237
C028025protoporphyrin IXprotoporphyrin IX results in decreased activity of HIF1A protein23624237
C028025protoporphyrin IXprotoporphyrin IX results in increased degradation of HIF1A protein23624237
C028025protoporphyrin IXprotoporphyrin IX inhibits the reaction [INS protein results in increased expression of HIF1A protein]23624237
C028025protoporphyrin IXprotoporphyrin IX inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]23624237
C432165pyrazolanthronepyrazolanthrone inhibits the reaction [andrographolide results in decreased expression of HIF1A protein]28651835
C432165pyrazolanthronepyrazolanthrone inhibits the reaction [manganese chloride results in increased expression of and results in increased activity of and results in increased stability of HIF1A protein]20152896
D011765Pyruvaldehyde[Glucose co-treated with Oxygen deficiency] promotes the reaction [Pyruvaldehyde binds to and results in decreased activity of HIF1A protein]18227068
D011765PyruvaldehydePyruvaldehyde binds to and results in decreased activity of HIF1A protein18227068
D011765PyruvaldehydeGLO1 protein inhibits the reaction [[Glucose co-treated with Oxygen deficiency] promotes the reaction [Pyruvaldehyde binds to and results in decreased activity of HIF1A protein]]18227068
D011765PyruvaldehydeReactive Oxygen Species promotes the reaction [Pyruvaldehyde binds to HIF1A protein]18227068
C587274Qing Ye DanQing Ye Dan inhibits the reaction [Testosterone results in increased expression of HIF1A protein]27866977
D011794QuercetinAscorbic Acid inhibits the reaction [Quercetin results in increased expression of HIF1A protein]17364964
D011794QuercetinCycloheximide inhibits the reaction [Quercetin results in increased expression of HIF1A protein]19958256
D011794Quercetinferric citrate inhibits the reaction [Quercetin results in increased expression of HIF1A mRNA]17364964
D011794Quercetinferric citrate inhibits the reaction [Quercetin results in increased expression of HIF1A protein]17364964
D011794Quercetinferrous sulfate inhibits the reaction [Quercetin results in increased expression of HIF1A protein]17973296
D011794QuercetinIron inhibits the reaction [Quercetin results in increased expression of and affects the localization of HIF1A protein]19729006
D011794QuercetinIron inhibits the reaction [Quercetin results in increased expression of HIF1A protein]17973296
D011794QuercetinQuercetin affects the localization of HIF1A protein20804812
D011794QuercetinQuercetin inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [HIF1A protein binds to VHL protein]]17973296
D011794QuercetinQuercetin inhibits the reaction [HIF1A protein binds to VHL protein]17973296
D011794QuercetinQuercetin inhibits the reaction [Hydrogen Peroxide results in increased expression of HIF1A protein]25108166
D011794QuercetinQuercetin inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A mRNA]11424089
D011794QuercetinQuercetin promotes the reaction [Oxygen deficiency promotes the reaction [HIF1A protein binds to EP300 protein]]20153296
D011794QuercetinQuercetin promotes the reaction [Oxygen deficiency results in increased expression of HIF1A protein]20153296
D011794Quercetin[Quercetin results in decreased abundance of Iron] which results in increased expression of HIF1A protein17364964
D011794QuercetinQuercetin results in decreased activity of HIF1A protein20804812
D011794QuercetinQuercetin results in decreased expression of HIF1A mRNA20596804
D011794QuercetinQuercetin results in decreased ubiquitination of and results in increased expression of HIF1A protein17973296
D011794Quercetin[Quercetin results in increased activity of SIRT1 protein] which results in increased expression of HIF1A protein22245592
D011794QuercetinQuercetin results in increased expression of and affects the localization of HIF1A protein19729006
D011794QuercetinQuercetin results in increased expression of and results in decreased degradation of and results in increased activity of and results in increased localization of HIF1A protein12054621
D011794QuercetinQuercetin results in increased expression of and results in increased activity of HIF1A protein19958256
D011794QuercetinQuercetin results in increased expression of HIF1A mRNA17364964
D011794QuercetinQuercetin results in increased expression of HIF1A protein22245592
D011794QuercetinQuercetin results in increased stability of and results in increased expression of HIF1A protein17364964
D011794QuercetinQuercetin results in increased stability of HIF1A protein19958256
D011794Quercetin"Quercetin inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of HIF1A protein]"21294050
D015363QuinolonesQuinolones inhibits the reaction [Mustard Gas inhibits the reaction [Oxygen deficiency results in increased stability of HIF1A protein]]26082309
D015363QuinolonesQuinolones promotes the reaction [Oxygen deficiency results in increased expression of HIF1A protein]26082309
D015363QuinolonesQuinolones results in increased expression of and affects the localization of HIF1A protein26082309
D011810QuinoxalinesQuinoxalines analog results in decreased expression of HIF1A mRNA11933073
D011810QuinoxalinesQuinoxalines analog results in decreased expression of HIF1A protein11933073
C058544R 59949R 59949 inhibits the reaction [cobaltous chloride results in increased activity of HIF1A protein]17082639
C058544R 59949R 59949 inhibits the reaction [cobaltous chloride results in increased expression of HIF1A protein]17082639
C058544R 59949R 59949 inhibits the reaction [rhodioloside promotes the reaction [cobaltous chloride results in increased expression of and affects the localization of HIF1A protein]]21499890
D011929Razoxaneferric nitrilotriacetate inhibits the reaction [Razoxane results in increased activity of HIF1A protein]18385176
D011929RazoxaneRazoxane results in increased activity of HIF1A protein18385176
D017382Reactive Oxygen Species[Arsenic results in increased abundance of Reactive Oxygen Species] which results in increased expression of HIF1A protein21687637
D017382Reactive Oxygen Species[[Arsenic results in increased abundance of Reactive Oxygen Species] which results in increased expression of HIF1A protein] which results in increased expression of VEGFA mRNA21687637
D017382Reactive Oxygen SpeciesCAT protein inhibits the reaction [[Arsenic results in increased abundance of Reactive Oxygen Species] which results in increased expression of HIF1A protein]21687637
D017382Reactive Oxygen SpeciesCAT protein inhibits the reaction [[[Arsenic results in increased abundance of Reactive Oxygen Species] which results in increased expression of HIF1A protein] which results in increased expression of VEGFA mRNA]21687637
D017382Reactive Oxygen Speciesdiphenyleneiodonium inhibits the reaction [[Arsenic results in increased abundance of Reactive Oxygen Species] which results in increased expression of HIF1A protein]21687637
D017382Reactive Oxygen Speciesdiphenyleneiodonium inhibits the reaction [[[Arsenic results in increased abundance of Reactive Oxygen Species] which results in increased expression of HIF1A protein] which results in increased expression of VEGFA mRNA]21687637
D017382Reactive Oxygen SpeciesReactive Oxygen Species affects the reaction [cobaltous chloride results in increased expression of HIF1A protein]17015263
D017382Reactive Oxygen SpeciesReactive Oxygen Species promotes the reaction [Pyruvaldehyde binds to HIF1A protein]18227068
D017382Reactive Oxygen SpeciesReactive Oxygen Species results in increased activity of HIF1A protein24221993
D017382Reactive Oxygen SpeciesReactive Oxygen Species results in increased expression of HIF1A mRNA16524376
D017382Reactive Oxygen Speciesresveratrol affects the reaction [Reactive Oxygen Species results in increased activity of HIF1A protein]24221993
C059514resveratrolbenzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [resveratrol inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]]24975222
C059514resveratrolresveratrol affects the expression of HIF1A protein17473185
C059514resveratrol"resveratrol inhibits the reaction [2,2'-Dipyridyl results in increased expression of HIF1A protein]"18674879
C059514resveratrolresveratrol inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Oxygen deficiency results in increased expression of HIF1A protein]]24975222
C059514resveratrolresveratrol inhibits the reaction [cobaltous chloride results in increased expression of HIF1A protein]25815440|2617495
C059514resveratrolresveratrol inhibits the reaction [HIF1A protein results in increased activity of AR protein]25297617
C059514resveratrolresveratrol inhibits the reaction [IGF1 protein results in increased expression of HIF1A protein]15297429
C059514resveratrolresveratrol inhibits the reaction [INS protein results in increased expression of HIF1A protein]15297429
C059514resveratrolresveratrol inhibits the reaction [lysophosphatidic acid results in increased expression of HIF1A protein]17919812
C059514resveratrolresveratrol inhibits the reaction [Oxygen deficiency affects the localization of HIF1A protein]25297617
C059514resveratrolresveratrol inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]18674879|2015329
C059514resveratrolresveratrol results in decreased expression of and affects the localization of HIF1A protein25297617
C059514resveratrolresveratrol results in decreased expression of HIF1A19828106
C059514resveratrolresveratrol results in decreased expression of HIF1A mRNA12002526
C059514resveratrolresveratrol results in decreased expression of HIF1A protein15297429|2331403
C059514resveratrol[resveratrol results in increased activity of SIRT1 protein] which results in increased expression of HIF1A protein22245592
C059514resveratrolresveratrol results in increased degradation of HIF1A protein15297429|1791981
C059514resveratrolresveratrol results in increased expression of HIF1A protein22245592
C059514resveratrolresveratrol results in increased ubiquitination of and results in increased degradation of HIF1A protein16227395
C059514resveratrolSIRT1 protein promotes the reaction [resveratrol inhibits the reaction [cobaltous chloride results in increased expression of HIF1A protein]]26174951
C059514resveratrolresveratrol inhibits the reaction [[Dietary Fats co-treated with Dietary Sucrose] results in decreased expression of HIF1A mRNA]27070252
C059514resveratrolbenzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [resveratrol results in decreased expression of HIF1A protein]24221993
C059514resveratrolresveratrol inhibits the reaction [Dextran Sulfate results in increased expression of HIF1A protein]26074695
C059514resveratrolresveratrol inhibits the reaction [Nicotine results in decreased expression of HIF1A mRNA]22687363
C059514resveratrolresveratrol results in decreased expression of HIF1A protein24221993
C059514resveratrol[resveratrol co-treated with plastochromanol 8] results in decreased expression of HIF1A protein22050707
C059514resveratrolresveratrol inhibits the reaction [Glucose results in increased expression of HIF1A mRNA]26891083
C059514resveratrolresveratrol inhibits the reaction [Glucose results in increased expression of HIF1A protein]26891083
C059514resveratrolresveratrol inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency co-treated with Oxygen] results in increased expression of HIF1A mRNA]23421680
C059514resveratrolresveratrol inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency co-treated with Oxygen] results in increased expression of HIF1A protein]23421680
C059514resveratrolresveratrol inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A mRNA]21914476
C059514resveratrolresveratrol results in decreased expression of HIF1A protein22050707
C059514resveratrolSIRT1 protein affects the reaction [resveratrol inhibits the reaction [Glucose results in increased expression of HIF1A protein]]26891083
C059514resveratrolresveratrol results in decreased expression of HIF1A protein24282676
C059514resveratrol[resveratrol results in decreased expression of HIF1A protein] which results in decreased susceptibility to SIAH2 mRNA24282676
C059514resveratrolHIF1A protein promotes the reaction [resveratrol results in decreased expression of VEGFA mRNA]15297429
C059514resveratrolresveratrol affects the reaction [Reactive Oxygen Species results in increased activity of HIF1A protein]24221993
C020491rheinrhein inhibits the reaction [cobaltous chloride results in increased expression of HIF1A protein]21457705
C020491rheinrhein results in decreased expression of HIF1A protein21457705
C009172rhodiolosideR 59949 inhibits the reaction [rhodioloside promotes the reaction [cobaltous chloride results in increased expression of and affects the localization of HIF1A protein]]21499890
C009172rhodioloside[rhodioloside co-treated with cobaltous chloride co-treated with NGF protein] results in decreased expression of HIF1A mRNA24989011
C009172rhodiolosiderhodioloside inhibits the reaction [[cobaltous chloride co-treated with NGF protein] results in increased expression of HIF1A protein]24989011
C009172rhodiolosiderhodioloside promotes the reaction [cobaltous chloride results in increased expression of and affects the localization of HIF1A protein]21499890
D012293Rifampin[Rifampin co-treated with NR1I2 protein] results in increased expression of HIF1A mRNA21127053
C089032rimonabantrimonabant inhibits the reaction [Dietary Fats results in increased expression of HIF1A mRNA]19030233
C087123romidepsinromidepsin inhibits the reaction [cobaltous chloride results in increased expression of HIF1A protein]21295294
C089730rosiglitazonerosiglitazone inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A mRNA]21926265
C089730rosiglitazonerosiglitazone inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A mRNA]21926265
D012402RotenoneRotenone inhibits the reaction [nickel chloride results in increased expression of HIF1A protein]22648416
D012402RotenoneRotenone inhibits the reaction [Oxygen deficiency results in decreased degradation of HIF1A protein]12376345
D012402RotenoneRotenone inhibits the reaction [Oxygen deficiency results in increased activity of HIF1A protein]19091749|1954249
D012402RotenoneRotenone inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]12062197|1909174
D012402RotenoneRotenone results in decreased expression of HIF1A protein20546814|2314469
D012402RotenoneRotenone results in increased expression of HIF1A mRNA22447502
D012402RotenoneRotenone results in increased expression of HIF1A mRNA22447502
D012402RotenoneRotenone inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]15913578
D012402RotenoneRotenone affects the expression of HIF1A protein16034640
D012402RotenoneSuccinic Acid inhibits the reaction [Rotenone affects the expression of HIF1A protein]16034640
C413684salicylaldehyde isonicotinoyl hydrazonesalicylaldehyde isonicotinoyl hydrazone affects the localization of HIF1A protein19679656
C413684salicylaldehyde isonicotinoyl hydrazone"[salicylaldehyde isonicotinoyl hydrazone co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine metabolite] affects the localization of HIF1A protein"19679656
C010327salinomycinsalinomycin results in decreased expression of HIF1A mRNA19682730
D012503SaponinsSaponins results in decreased expression of HIF1A mRNA27369806
C410958sauchinonesauchinone inhibits the reaction [cobaltous chloride results in increased expression of HIF1A protein]25451574|2787189
C410958sauchinonesauchinone inhibits the reaction [TGFB1 protein results in increased expression of HIF1A protein]25451574
C093642SB 203580SB 203580 inhibits the reaction [cobaltous chloride results in increased activity of HIF1A protein]17082639
C093642SB 203580SB 203580 inhibits the reaction [cobaltous chloride results in increased expression of HIF1A mRNA]27297870
C093642SB 203580SB 203580 inhibits the reaction [cobaltous chloride results in increased expression of HIF1A protein]17082639|2729787
C093642SB 203580SB 203580 inhibits the reaction [manganese chloride results in increased expression of and results in increased activity of and results in increased stability of HIF1A protein]20152896
C093642SB 203580SB 203580 inhibits the reaction [manganese chloride results in increased expression of and results in increased activity of HIF1A protein]20152896
C093642SB 203580SB 203580 inhibits the reaction [[nickel sulfate co-treated with Dinoprostone] results in increased expression of HIF1A protein]23526216
C093642SB 203580SB 203580 inhibits the reaction [nickel sulfate results in increased expression of HIF1A protein]23526216
C093642SB 203580SB 203580 inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]13679210
C093642SB 203580SB 203580 inhibits the reaction [sodium arsenite results in increased expression of HIF1A protein]12482858
C093642SB 203580SB 203580 results in decreased expression of HIF1A protein14695184
C093642SB 203580[U 0126 co-treated with SB 203580] inhibits the reaction [[nickel sulfate co-treated with macrophage stimulatory lipopeptide 2] results in increased expression of HIF1A protein]20600219
C484876scutellarinbenzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [scutellarin inhibits the reaction [[cobaltous chloride co-treated with Glucose] results in increased expression of HIF1A protein]]25192544
C484876scutellarinbenzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [scutellarin results in decreased expression of HIF1A protein]25192544
C484876scutellarinepoxomicin inhibits the reaction [scutellarin inhibits the reaction [[cobaltous chloride co-treated with Glucose] results in increased expression of HIF1A protein]]25192544
C484876scutellarinepoxomicin inhibits the reaction [scutellarin results in decreased expression of HIF1A protein]25192544
C484876scutellarinMG 262 inhibits the reaction [scutellarin inhibits the reaction [[cobaltous chloride co-treated with Glucose] results in increased expression of HIF1A protein]]25192544
C484876scutellarinMG 262 inhibits the reaction [scutellarin results in decreased expression of HIF1A protein]25192544
C484876scutellarinscutellarin inhibits the reaction [[cobaltous chloride co-treated with Glucose co-treated with Cycloheximide] results in decreased expression of HIF1A protein]25192544
C484876scutellarinscutellarin inhibits the reaction [[cobaltous chloride co-treated with Glucose] promotes the reaction [HIF1A protein binds to EP300 protein]]25192544
C484876scutellarinscutellarin inhibits the reaction [[cobaltous chloride co-treated with Glucose] results in increased expression of and results in decreased ubiquitination of HIF1A protein]25192544
C484876scutellarinscutellarin promotes the reaction [Cycloheximide inhibits the reaction [[cobaltous chloride co-treated with Glucose] results in increased expression of HIF1A protein]]25192544
C484876scutellarinscutellarin results in decreased expression of HIF1A protein25192544
C116890SemaxinibSemaxinib results in decreased expression of HIF1A protein15474452
D012715Sesame OilSesame Oil results in decreased expression of HIF1A mRNA29191790
C016101shikoninshikonin inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]28684144
C016101shikoninshikonin results in decreased expression of HIF1A protein28684144
D019821SimvastatinHIF1A mutant form inhibits the reaction [Simvastatin results in increased expression of VEGFA mRNA]18356691
D019821SimvastatinSimvastatin results in increased expression of HIF1A protein18356691
D019821SimvastatinSimvastatin results in decreased expression of HIF1A mRNA21844074
D020123Sirolimus[Curcumin analog co-treated with Sirolimus] inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]20554536
D020123SirolimusSirolimus inhibits the reaction [4-hydroxyestradiol results in increased expression of HIF1A protein]15050414
D020123SirolimusSirolimus inhibits the reaction [Cadmium Chloride results in increased expression of HIF1A protein]21984483
D020123SirolimusSirolimus inhibits the reaction [[Dinoprostone binds to and results in increased activity of PTGER1 protein] which results in increased expression of HIF1A protein]20335389
D020123SirolimusSirolimus inhibits the reaction [IGF1 protein results in increased expression of HIF1A protein]15297429|1668245
D020123SirolimusSirolimus inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A mRNA]19640849
D020123SirolimusSirolimus inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]17968710
D020123SirolimusSirolimus inhibits the reaction [sulprostone results in increased expression of HIF1A protein]20335389
D020123SirolimusSirolimus results in decreased expression of HIF1A protein15634505
D020123SirolimusSirolimus results in decreased expression of HIF1A mRNA19335982
D012964SodiumHIF1A protein results in increased secretion of Sodium22349312
C009277sodium arsenatesodium arsenate results in increased expression of HIF1A mRNA16882884
C009277sodium arsenatesodium arsenate results in increased expression of HIF1A mRNA21795629
C017947sodium arsenite2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [sodium arsenite results in increased expression of HIF1A protein]23968725
C017947sodium arsenite4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [sodium arsenite results in increased expression of HIF1A protein]12482858
C017947sodium arseniteAcetylcysteine inhibits the reaction [sodium arsenite results in increased expression of HIF1A protein]11641398
C017947sodium arseniteAscorbic Acid inhibits the reaction [sodium arsenite results in decreased hydroxylation of HIF1A protein]19074761
C017947sodium arseniteAscorbic Acid inhibits the reaction [sodium arsenite results in increased expression of HIF1A protein]24188932
C017947sodium arseniteAscorbic Acid inhibits the reaction [sodium arsenite results in increased stability of HIF1A protein]19074761|2418893
C017947sodium arsenitebenzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [MALAT1 mRNA affects the reaction [sodium arsenite results in increased expression of HIF1A protein]]27287256
C017947sodium arseniteButhionine Sulfoximine promotes the reaction [sodium arsenite results in increased expression of HIF1A protein]11641398
C017947sodium arseniteCycloheximide inhibits the reaction [sodium arsenite results in increased expression of HIF1A protein]11641398
C017947sodium arseniteCycloheximide inhibits the reaction [sodium arsenite results in increased stability of HIF1A protein]24188932
C017947sodium arseniteERN1 affects the reaction [sodium arsenite results in increased expression of HIF1A protein]28973481
C017947sodium arseniteferrous chloride inhibits the reaction [sodium arsenite results in decreased hydroxylation of HIF1A protein]24188932
C017947sodium arseniteferrous chloride inhibits the reaction [sodium arsenite results in increased expression of HIF1A protein]24188932
C017947sodium arseniteGlutathione inhibits the reaction [sodium arsenite results in increased expression of HIF1A protein]11641398
C017947sodium arseniteHIF1A affects the reaction [sodium arsenite results in increased expression of ACE mRNA]28973481
C017947sodium arseniteHIF1A affects the reaction [sodium arsenite results in increased expression of AGT mRNA]28973481
C017947sodium arseniteHIF1A affects the reaction [sodium arsenite results in increased expression of AGTR1 mRNA]28973481
C017947sodium arseniteHIF1A affects the reaction [sodium arsenite results in increased expression of and results in increased secretion of AGT protein modified form]28973481
C017947sodium arseniteHIF1A affects the reaction [sodium arsenite results in increased expression of SELE protein]28973481
C017947sodium arseniteHIF1A affects the reaction [sodium arsenite results in increased secretion of CCL2 protein]28973481
C017947sodium arseniteHIF1A affects the reaction [sodium arsenite results in increased secretion of CXCL8 protein]28973481
C017947sodium arseniteHIF1A affects the reaction [sodium arsenite results in increased secretion of ICAM1 protein]28973481
C017947sodium arseniteHIF1A protein affects the reaction [sodium arsenite results in decreased phosphorylation of TP53 protein]27287256
C017947sodium arseniteHIF1A protein affects the reaction [sodium arsenite results in increased expression of and affects the localization of SLC2A4 protein]27287256
C017947sodium arseniteHIF1A protein affects the reaction [sodium arsenite results in increased expression of ENO1 protein]27287256
C017947sodium arseniteHIF1A protein affects the reaction [sodium arsenite results in increased expression of HK2 protein]27287256
C017947sodium arseniteHIF1A protein affects the reaction [sodium arsenite results in increased phosphorylation of RELA protein]27287256
C017947sodium arseniteHIF1A protein inhibits the reaction [MALAT1 mRNA affects the reaction [sodium arsenite results in increased expression of ENO1 protein]]27287256
C017947sodium arseniteHIF1A protein inhibits the reaction [MALAT1 mRNA affects the reaction [sodium arsenite results in increased expression of HK2 protein]]27287256
C017947sodium arseniteHIF1A protein inhibits the reaction [MALAT1 mRNA affects the reaction [sodium arsenite results in increased expression of SLC2A4 protein]]27287256
C017947sodium arseniteMALAT1 mRNA affects the reaction [sodium arsenite inhibits the reaction [HIF1A protein binds to VHL protein]]27287256
C017947sodium arseniteMALAT1 mRNA affects the reaction [sodium arsenite results in decreased ubiquitination of HIF1A protein]27287256
C017947sodium arseniteMALAT1 mRNA affects the reaction [sodium arsenite results in increased expression of HIF1A protein]27287256
C017947sodium arsenite"Mn(III) 5,10,15,20-tetrakis(N-methylpyridinium-2-yl)porphyrin inhibits the reaction [sodium arsenite results in increased expression of HIF1A protein]"24188932
C017947sodium arsenite"Mn(III) 5,10,15,20-tetrakis(N-methylpyridinium-2-yl)porphyrin inhibits the reaction [sodium arsenite results in increased stability of HIF1A protein]"24188932
C017947sodium arsenitePRKAA1 protein affects the reaction [sodium arsenite results in increased expression of HIF1A protein]16678800
C017947sodium arseniteSB 203580 inhibits the reaction [sodium arsenite results in increased expression of HIF1A protein]12482858
C017947sodium arsenite[sodium arsenite co-treated with Ethanol] affects the localization of HIF1A protein22872060
C017947sodium arsenitesodium arsenite inhibits the reaction [HIF1A protein binds to VHL protein]27287256
C017947sodium arsenitesodium arsenite promotes the reaction [XBP1 protein binds to HIF1A protein]28973481
C017947sodium arsenitesodium arsenite promotes the reaction [[XBP1 protein binds to HIF1A protein] which binds to ACE enhancer]28973481
C017947sodium arsenitesodium arsenite promotes the reaction [[XBP1 protein binds to HIF1A protein] which binds to AGT enhancer]28973481
C017947sodium arsenitesodium arsenite promotes the reaction [[XBP1 protein binds to HIF1A protein] which binds to AGTR1 enhancer]28973481
C017947sodium arsenitesodium arsenite results in decreased hydroxylation of HIF1A protein19074761|2418893
C017947sodium arsenitesodium arsenite results in decreased ubiquitination of HIF1A protein27287256
C017947sodium arsenitesodium arsenite results in increased expression of and affects the localization of HIF1A protein12482858
C017947sodium arsenitesodium arsenite results in increased expression of and results in decreased degradation of HIF1A protein11641398
C017947sodium arsenitesodium arsenite results in increased expression of and results in increased activity of HIF1A protein28973481
C017947sodium arsenitesodium arsenite results in increased expression of HIF1A mRNA12760830|2033913
C017947sodium arsenitesodium arsenite results in increased expression of HIF1A protein16678800|2364839
C017947sodium arsenitesodium arsenite results in increased stability of HIF1A protein19074761|2418893
C017947sodium arseniteU 0126 inhibits the reaction [sodium arsenite results in increased expression of HIF1A protein]23968725
C017947sodium arsenitewortmannin inhibits the reaction [sodium arsenite results in increased expression of HIF1A protein]23968725
C017947sodium arseniteXBP1 affects the reaction [sodium arsenite results in increased expression of HIF1A protein]28973481
C017947sodium arsenitesodium arsenite results in increased expression of HIF1A protein12482858
C017947sodium arsenitebisindolylmaleimide I inhibits the reaction [sodium arsenite results in increased expression of HIF1A mRNA]15089098
C017947sodium arseniteGo 6976 inhibits the reaction [sodium arsenite results in increased expression of HIF1A mRNA]15089098
C017947sodium arsenitesodium arsenite results in increased expression of HIF1A mRNA15089098
C017947sodium arsenitesodium arsenite results in increased expression of HIF1A protein15089098
D012965Sodium ChlorideSodium Chloride results in increased expression of HIF1A protein20232302
D012965Sodium Chloridetempol inhibits the reaction [Sodium Chloride results in increased expression of HIF1A protein]20232302
D017673Sodium Chloride, Dietary"EGLN1 inhibits the reaction [Sodium Chloride, Dietary results in increased expression of HIF1A protein]"20308610
D017673Sodium Chloride, Dietary"HIF1A protein results in decreased susceptibility to Sodium Chloride, Dietary"22349312
D017673Sodium Chloride, Dietary"Sodium Chloride, Dietary results in increased expression of HIF1A protein"20308610
D020358Sodium Cholate[cocoa butter co-treated with Sodium Cholate co-treated with Cholesterol] results in increased expression of HIF1A mRNA26606054
D012977Sodium NitriteCarnosine inhibits the reaction [Sodium Nitrite results in increased expression of HIF1A protein]28266762
D012977Sodium NitriteSodium Nitrite results in increased expression of HIF1A protein28266762
D053260SootSoot results in increased expression of HIF1A mRNA26551751
C471405sorafenibsorafenib results in decreased expression of HIF1A mRNA26409325
D013148SpironolactoneSpironolactone results in increased expression of HIF1A protein20228418
D013311StreptozocinStreptozocin results in increased expression of HIF1A protein26073000
D010042Ouabain2-(2-(4-(4-nitrobenzyloxy)phenyl)ethyl)isothiourea methanesulfonate inhibits the reaction [Ouabain affects the localization of HIF1A protein]19647009
D010042Ouabain2-(2-(4-(4-nitrobenzyloxy)phenyl)ethyl)isothiourea methanesulfonate inhibits the reaction [Ouabain results in increased phosphorylation of HIF1A protein]19647009
D010042Ouabain3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole inhibits the reaction [Ouabain affects the localization of HIF1A protein]19647009
D010042OuabainKN 93 inhibits the reaction [Ouabain affects the localization of HIF1A protein]19647009
D010042OuabainKN 93 inhibits the reaction [Ouabain results in increased phosphorylation of HIF1A protein]19647009
D010042OuabainOuabain affects the localization of HIF1A protein19647009
D010042OuabainOuabain results in increased activity of HIF1A protein19647009
D010042OuabainOuabain results in increased phosphorylation of and results in increased expression of HIF1A protein19647009
C105686SU 5402SU 5402 inhibits the reaction [FGF2 protein results in increased expression of and results in increased activity of HIF1A protein]15631803
D019802Succinic AcidSuccinic Acid inhibits the reaction [Rotenone affects the expression of HIF1A protein]16034640
D013412Sulfadimethoxine[Complex Mixtures co-treated with Sulfadimethoxine] results in increased expression of HIF1A mRNA22687987
D012460SulfasalazineSulfasalazine inhibits the reaction [TNF protein results in increased expression of HIF1A protein]12808024
D012460SulfasalazineSulfasalazine results in increased activity of HIF1A protein19502547
C016766sulforafansulforafan results in decreased expression of HIF1A protein27993529
D013467SulindacAKT1 protein affects the reaction [Sulindac analog results in decreased expression of HIF1A protein]18924134
D013467Sulindac[AKT1 protein affects the reaction [Sulindac analog results in decreased expression of HIF1A protein]] which affects the susceptibility to Oxygen18924134
D013467SulindacSulindac analog results in decreased expression of HIF1A mRNA18924134
D013467SulindacSulindac analog results in decreased expression of HIF1A protein18924134
C016767sulprostonePertussis Toxin inhibits the reaction [sulprostone results in increased expression of HIF1A protein]20335389
C016767sulprostoneSirolimus inhibits the reaction [sulprostone results in increased expression of HIF1A protein]20335389
C016767sulprostonesulprostone results in increased expression of HIF1A protein20335389
C013270swertiamarinswertiamarin inhibits the reaction [Testosterone results in increased expression of HIF1A protein]27866977
D014284TriiodothyronineTriiodothyronine results in increased expression of HIF1A mRNA15507505
D013629TamoxifenHIF1A protein results in decreased susceptibility to Tamoxifen19671742
C112765tanespimycintanespimycin promotes the reaction [COMMD1 protein results in increased degradation of HIF1A protein]19802386
C001803tempoltempol inhibits the reaction [Sodium Chloride results in increased expression of HIF1A protein]20232302
C001803tempoltempol results in increased expression of HIF1A protein12595275
C080890terpestacin[Curcumin analog co-treated with terpestacin] inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]20554536
D013739TestosteroneTestosterone results in decreased expression of HIF1A mRNA21669218
D013739TestosteroneFinasteride inhibits the reaction [Testosterone results in increased expression of HIF1A protein]27866977
D013739TestosteroneQing Ye Dan inhibits the reaction [Testosterone results in increased expression of HIF1A protein]27866977
D013739Testosteroneswertiamarin inhibits the reaction [Testosterone results in increased expression of HIF1A protein]27866977
D013739TestosteroneTestosterone results in increased expression of HIF1A protein27866977
C045037testosterone-3-carboxymethyloxime-bovine serum albumin conjugatetestosterone-3-carboxymethyloxime-bovine serum albumin conjugate affects the expression of HIF1A mRNA20189893
C004648testosterone enanthatetestosterone enanthate results in decreased expression of HIF1A mRNA23085480
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A mRNA]14991911
D013749Tetrachlorodibenzodioxin[Oxygen deficiency co-treated with Tetrachlorodibenzodioxin] results in decreased stability of HIF1A protein18072750
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of HIF1A mRNA22298810
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of HIF1A mRNA18343893|2157046
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin promotes the reaction [AHR protein binds to HIF1A gene]28213091
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of HIF1A mRNA15328365|1946511
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased expression of HIF1A mRNA21215274
C524826tetraconazoletetraconazole results in increased activity of HIF1A protein20143881
D013755Tetradecanoylphorbol Acetate2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of HIF1A protein alternative form]14695184
D013755Tetradecanoylphorbol AcetateDithiothreitol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of HIF1A protein alternative form]14695184
D013755Tetradecanoylphorbol AcetateTetradecanoylphorbol Acetate inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A mRNA]11424089
D013755Tetradecanoylphorbol AcetateTetradecanoylphorbol Acetate results in increased expression of HIF1A mRNA alternative form14695184
D013755Tetradecanoylphorbol AcetateTetradecanoylphorbol Acetate results in increased expression of HIF1A protein alternative form14695184
D013755Tetradecanoylphorbol AcetateTetradecanoylphorbol Acetate results in increased expression of HIF1A protein12479793
C034269tetraethylenepentamineCopper Sulfate affects the reaction [tetraethylenepentamine affects the localization of HIF1A protein]25687434
C034269tetraethylenepentaminetetraethylenepentamine affects the expression of and affects the localization of HIF1A protein25687434
C034269tetraethylenepentaminetetraethylenepentamine inhibits the reaction [cobaltous chloride results in increased activity of HIF1A protein]26174737
C034269tetraethylenepentaminetetraethylenepentamine inhibits the reaction [cobaltous chloride results in increased expression of and affects the localization of HIF1A protein]26174737
C017953tetramethylpyrazineNFE2L2 affects the reaction [tetramethylpyrazine inhibits the reaction [Ethanol results in increased expression of HIF1A mRNA]]27837167
C017953tetramethylpyrazineNFE2L2 affects the reaction [tetramethylpyrazine inhibits the reaction [Ethanol results in increased expression of HIF1A protein]]27837167
C017953tetramethylpyrazinetetramethylpyrazine inhibits the reaction [Ethanol results in increased expression of HIF1A mRNA]27837167
C017953tetramethylpyrazinetetramethylpyrazine inhibits the reaction [Ethanol results in increased expression of HIF1A protein]27837167
C020809tetrathiomolybdate[Copper deficiency co-treated with tetrathiomolybdate] inhibits the reaction [EP300 protein binds to HIF1A protein]22276220
C020809tetrathiomolybdate[Copper deficiency co-treated with tetrathiomolybdate] results in decreased expression of HIF1A protein22276220
D013853ThioacetamideThioacetamide affects the expression of HIF1A mRNA28903497
D013936Thymidine[Thymidine co-treated with TYMP co-treated with Oxygen deficiency] results in increased expression of HIF1A protein15841086
C031462titanium alloy (TiAl6V4)titanium alloy (TiAl6V4) results in increased expression of HIF1A protein23840602
C009495titanium dioxideAcetylcysteine inhibits the reaction [titanium dioxide results in increased expression of HIF1A protein]25406100
C009495titanium dioxidetitanium dioxide results in increased expression of HIF1A protein25406100
C009495titanium dioxideAcetylcysteine inhibits the reaction [titanium dioxide results in increased expression of HIF1A protein]25406100
C009495titanium dioxidepimagedine inhibits the reaction [titanium dioxide results in increased expression of HIF1A protein]25406100
C009495titanium dioxidetitanium dioxide results in increased expression of HIF1A protein25406100|2864648
D014028Tobacco Smoke PollutionTobacco Smoke Pollution results in decreased expression of HIF1A mRNA27404394
D014028Tobacco Smoke PollutionTobacco Smoke Pollution results in increased expression of HIF1A mRNA27865774
D019772TopotecanTopotecan inhibits the reaction [Cisplatin affects the localization of HIF1A protein]20935474
D019772TopotecanTopotecan inhibits the reaction [Cisplatin promotes the reaction [HIF1A protein binds to VEGFA promoter]]20935474
D019772TopotecanTopotecan results in decreased expression of HIF1A protein15930297
D019772Topotecan[oxaliplatin co-treated with Topotecan] results in increased expression of HIF1A mRNA25729387
D014212TretinoinHIF1A protein affects the susceptibility to Tretinoin19285840
D014212Tretinoin[nickel chloride co-treated with Tretinoin] results in increased expression of HIF1A protein25614230
D014212TretinoinTretinoin results in increased expression of HIF1A protein19285840
D014223TriamtereneTriamterene results in increased activity of HIF1A protein19502547
C447082tricarbonyldichlororuthenium (II) dimertricarbonyldichlororuthenium (II) dimer inhibits the reaction [cobaltous chloride results in increased expression of HIF1A mRNA]27297870
C447082tricarbonyldichlororuthenium (II) dimertricarbonyldichlororuthenium (II) dimer inhibits the reaction [cobaltous chloride results in increased expression of HIF1A protein]27297870
C447082tricarbonyldichlororuthenium (II) dimer[tricarbonyldichlororuthenium (II) dimer co-treated with Doxorubicin] results in increased expression of HIF1A mRNA21443895
D014268TrifluoperazineTrifluoperazine results in decreased expression of HIF1A protein18822394
C015559trimellitic anhydridetrimellitic anhydride results in increased expression of HIF1A mRNA19042947
C046488trimethyltintrimethyltin results in increased expression of HIF1A mRNA24002884
C000588561tris(4-methyl-1-pyrazolyl)borohydridetris(4-methyl-1-pyrazolyl)borohydride results in increased expression of HIF1A protein24412237
C057693troglitazonetroglitazone affects the localization of and results in increased expression of HIF1A protein20846491
C002802tungsten carbide[tungsten carbide co-treated with Cobalt] results in increased expression of and results in increased stability of HIF1A protein23052192
D014415TunicamycinTunicamycin results in increased expression of HIF1A mRNA24370435
C113580U 0126[U 0126 co-treated with SB 203580] inhibits the reaction [[nickel sulfate co-treated with macrophage stimulatory lipopeptide 2] results in increased expression of HIF1A protein]20600219
C113580U 0126U 0126 inhibits the reaction [Cadmium Chloride results in increased expression of HIF1A protein]21984483
C113580U 0126U 0126 inhibits the reaction [cobaltous chloride results in increased expression of HIF1A protein]20452389
C113580U 0126U 0126 inhibits the reaction [Nickel results in increased expression of HIF1A protein]11504687
C113580U 0126U 0126 inhibits the reaction [[nickel sulfate co-treated with macrophage stimulatory lipopeptide 2] results in increased expression of HIF1A protein]20600219
C113580U 0126U 0126 inhibits the reaction [Nitric Oxide results in decreased degradation of and results in increased activity of HIF1A protein]18424783
C113580U 0126U 0126 inhibits the reaction [sodium arsenite results in increased expression of HIF1A protein]23968725
C113580U 0126"U 0126 promotes the reaction [1-hydroxy-2-oxo-3,3-bis(2-aminoethyl)-1-triazene results in decreased degradation of HIF1A protein]"18424783
C113580U 0126U 0126 results in decreased degradation of HIF1A protein18424783
C113580U 0126U 0126 results in decreased expression of HIF1A protein20452389
C113580U 0126[wortmannin co-treated with U 0126] inhibits the reaction [IGF1 protein promotes the reaction [cobaltous chloride results in increased expression of HIF1A protein]]16499871
C419664udenafiludenafil results in decreased expression of HIF1A21366883
D014520UrethaneUrethane results in decreased expression of HIF1A mRNA28818685
D014635Valproic AcidValproic Acid affects the expression of HIF1A mRNA25979313
D014635Valproic AcidValproic Acid results in decreased methylation of HIF1A gene29154799
D014635Valproic AcidValproic Acid results in decreased expression of HIF1A mRNA20546886
D014638VanadatesAscorbic Acid inhibits the reaction [Vanadates results in decreased hydroxylation of HIF1A protein]19074761
D014638VanadatesAscorbic Acid inhibits the reaction [Vanadates results in increased stability of HIF1A protein]19074761
D014638VanadatesCAT protein inhibits the reaction [Vanadates results in increased expression of HIF1A protein]16678800
D014638VanadatesGlutathione inhibits the reaction [Vanadates results in increased expression of HIF1A protein]16678800
D014638VanadatesPRKAA1 protein affects the reaction [Vanadates results in increased expression of HIF1A protein]16678800
D014638VanadatesVanadates results in decreased hydroxylation of HIF1A protein19074761
D014638VanadatesVanadates results in increased expression of and results in increased activity of HIF1A protein15297373
D014638VanadatesVanadates results in increased expression of HIF1A protein16678800
D014638VanadatesVanadates results in increased stability of HIF1A protein19074761
D014639VanadiumVanadium results in increased expression of and results in increased activity of HIF1A protein16386771
D001335Vehicle EmissionsVehicle Emissions inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of HIF1A protein]28400208
D001335Vehicle EmissionsVehicle Emissions affects the methylation of HIF1A gene25560391
D001335Vehicle EmissionsVehicle Emissions results in decreased expression of HIF1A protein23887904
D001335Vehicle EmissionsVehicle Emissions results in increased expression of HIF1A mRNA24216475
C551177vemurafenibvemurafenib results in increased expression of HIF1A mRNA26684239
C025643vinclozolinvinclozolin results in increased expression of HIF1A mRNA23555832
D002762CholecalciferolCholecalciferol results in increased expression of HIF1A mRNA16508948|1717007
D014810Vitamin EVitamin E results in decreased expression of HIF1A protein16507596
D024483Vitamin K 3Vitamin K 3 results in increased expression of HIF1A mRNA16507596
D024483Vitamin K 3Vitamin K 3 results in increased expression of HIF1A protein16507596
D024483Vitamin K 3Vitamin K 3 inhibits the reaction [carbobenzoxy-leucyl-leucyl-leucine results in increased expression of HIF1A protein]12595275
D024483Vitamin K 3Vitamin K 3 inhibits the reaction [cobaltous chloride results in increased expression of HIF1A protein]12595275
D024483Vitamin K 3Vitamin K 3 inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]12595275
C111237vorinostat[Curcumin analog co-treated with vorinostat] inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]20554536
C111237vorinostatTNFSF10 protein promotes the reaction [vorinostat results in decreased expression of HIF1A protein]19509267
C111237vorinostatvorinostat results in decreased expression of HIF1A protein19509267|2716385
D014874Water Pollutants, Chemical"Water Pollutants, Chemical results in increased expression of HIF1A mRNA"25208076
C085514wogonin"wogonin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of HIF1A protein]"26213241
C009687wortmannin[wortmannin co-treated with U 0126] inhibits the reaction [IGF1 protein promotes the reaction [cobaltous chloride results in increased expression of HIF1A protein]]16499871
C009687wortmanninwortmannin inhibits the reaction [4-hydroxyestradiol results in increased expression of HIF1A protein]15050414
C009687wortmanninwortmannin inhibits the reaction [cobaltous chloride results in increased expression of HIF1A protein]13679210
C009687wortmanninwortmannin inhibits the reaction [CR 3294 results in decreased expression of HIF1A protein]18927491
C009687wortmanninwortmannin inhibits the reaction [[Dinoprostone binds to and results in increased activity of PTGER1 protein] which results in increased expression of HIF1A protein]20335389
C009687wortmanninwortmannin inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A mRNA]11424089|1964084
C009687wortmanninwortmannin inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]20153296
C009687wortmanninwortmannin inhibits the reaction [sodium arsenite results in increased expression of HIF1A protein]23968725
C009687wortmanninwortmannin results in decreased expression of HIF1A protein14726529
C009687wortmanninwortmannin inhibits the reaction [S-Nitrosoglutathione results in increased expression of HIF1A protein]11514583
C009687wortmanninwortmannin inhibits the reaction [TNF protein results in increased expression of HIF1A protein]11514583
D019820Xanthine[Xanthine co-treated with XDH protein] inhibits the reaction [carbobenzoxy-leucyl-leucyl-leucine results in increased expression of HIF1A protein]12595275
D019820Xanthine[Xanthine co-treated with XDH protein] inhibits the reaction [cobaltous chloride results in increased expression of HIF1A protein]12595275
D019820Xanthine[Xanthine co-treated with XDH protein] inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]12595275
C108830Y 27632Y 27632 promotes the reaction [cobaltous chloride affects the localization of HIF1A protein]16772336
D065146Zeaxanthins[BCO2 gene mutant form results in decreased metabolism of Zeaxanthins] which results in increased expression of HIF1A protein21106934
D015032Zinc[Zinc co-treated with Copper] inhibits the reaction [Clioquinol results in increased expression of HIF1A protein]16973622
D015032ZincZinc inhibits the reaction [ARNT protein binds to HIF1A protein]11739637
D015032Zinc"Zinc inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased stability of and results in increased expression of HIF1A protein]"16579968
D015032Zinc[Zinc results in decreased localization of ARNT protein] inhibits the reaction [ARNT protein binds to HIF1A protein]11739637
D015032Zinc[Zinc results in increased expression of HIF1A mRNA alternative form] which results in decreased localization of ARNT protein11739637
D015032ZincZinc results in increased expression of HIF1A protein16330433
D019345Zinc Acetate[motexafin gadolinium co-treated with Zinc Acetate] results in increased expression of HIF1A protein16357179
D019345Zinc AcetateZinc Acetate results in increased expression of HIF1A protein16357179
C016837zinc chlorideCycloheximide inhibits the reaction [zinc chloride results in increased expression of HIF1A protein alternative form]11739637
C016837zinc chloridezinc chloride affects the splicing of HIF1A mRNA11739637
C016837zinc chloridezinc chloride inhibits the reaction [cobaltous chloride inhibits the reaction [Doxorubicin promotes the reaction [HIPK2 protein binds to HIF1A promoter]]]19714248
C016837zinc chloridezinc chloride inhibits the reaction [cobaltous chloride results in increased expression of HIF1A protein]19714248
C016837zinc chloride"zinc chloride inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased stability of and results in increased expression of HIF1A protein]"16579968
C016837zinc chloridezinc chloride inhibits the reaction [Oxygen deficiency results in increased activity of HIF1A protein]11090055
C016837zinc chloridezinc chloride inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]19714248
C016837zinc chloridezinc chloride results in increased expression of HIF1A mRNA11739637
C016837zinc chloridezinc chloride results in increased expression of HIF1A mRNA alternative form11739637
C016837zinc chloridezinc chloride results in increased expression of HIF1A protein alternative form11739637
C016837zinc chloride[Doxorubicin co-treated with zinc chloride] results in decreased expression of HIF1A mRNA19714248
C017803zinc protoporphyrinzinc protoporphyrin inhibits the reaction [HIF1A protein results in increased activity of SOD2 protein]17066447
C478783ZM323881ZM323881 inhibits the reaction [[cobaltous chloride co-treated with VEGFA protein] results in increased expression of HIF1A protein]16499871
C478783ZM323881ZM323881 results in decreased expression of HIF1A protein16499871
C088658zoledronic acidzoledronic acid inhibits the reaction [Dopamine results in decreased expression of HIF1A protein]25818600

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0000981RNA polymerase II transcription factor activity, sequence-specific DNA binding-IBA21873635  
GO:0000981RNA polymerase II transcription factor activity, sequence-specific DNA binding-IDA25043030  
GO:0000981RNA polymerase II transcription factor activity, sequence-specific DNA binding-ISA-  
GO:0000981RNA polymerase II transcription factor activity, sequence-specific DNA binding-ISM19274049  
GO:0000981RNA polymerase II transcription factor activity, sequence-specific DNA binding-NAS19274049  
GO:0001076transcription factor activity, RNA polymerase II transcription factor binding-IEA-  
GO:0001077transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding-IEA-  
GO:0001228transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding-IMP24983504  
GO:0002039p53 binding-IPI15629713  
GO:0003700DNA-binding transcription factor activity-IDA11782478  18658046  
GO:0003700DNA-binding transcription factor activity-TAS15261140  
GO:0003705transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding-IDA8387214  9079689  
GO:0003705transcription factor activity, RNA polymerase II distal enhancer sequence-specific bindingcontributes_toIDA7539918  8756616  
GO:0005515protein binding-IPI9704006  9887100  11292862  11389899  12004076  12050673  
12446723  15261140  15474027  15721254  16288748  16424018  
16511565  16543236  16638120  17003112  17024177  17353276  
17382325  17426252  18268343  18323857  18427106  18509053  
18775313  19071119  19168635  19680224  20562859  20603618  
20661221  20840591  20932347  21602890  21620138  21685944  
21871655  22128162  22801492  22903062  23469069  23746844  
24378640  24421387  24434214  24650032  24670641  24681946  
24899725  25043030  25438054  25974097  26517842  26751287  
26752685  26972000  
GO:0008134transcription factor binding-IPI7539918  
GO:0019899enzyme binding-IPI11641274  
GO:0019901protein kinase binding-IPI20889502  
GO:0019904protein domain specific binding-IPI14594809  
GO:0031625ubiquitin protein ligase binding-IPI11641274  
GO:0035035histone acetyltransferase binding-IPI15261140  
GO:0035257nuclear hormone receptor binding-IPI18658046  
GO:0042826histone deacetylase binding-IEA-  
GO:0043565sequence-specific DNA bindingcontributes_toIDA7539918  8756616  9079689  
GO:0046982protein heterodimerization activity-IPI9079689  12239177  
GO:0046982protein heterodimerization activity-TAS15261140  
GO:0051879Hsp90 protein binding-IDA9079689  
GO:0070888E-box binding-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO:0001525angiogenesis-IEA-  
GO:0001666response to hypoxia-IDA8756616  9887100  11782478  15261140  18419598  
GO:0001666response to hypoxia-IMP12411310  
GO:0001755neural crest cell migration-IEA-  
GO:0001837epithelial to mesenchymal transition-ISS18037992  
GO:0001892embryonic placenta development-IEA-  
GO:0001922B-1 B cell homeostasis-IEA-  
GO:0001938positive regulation of endothelial cell proliferation-IC8756616  
GO:0001947heart looping-IEA-  
GO:0002052positive regulation of neuroblast proliferation-IEA-  
GO:0002248connective tissue replacement involved in inflammatory response wound healing-ISS18037992  
GO:0003151outflow tract morphogenesis-IEA-  
GO:0003208cardiac ventricle morphogenesis-IEA-  
GO:0006089lactate metabolic process-IEA-  
GO:0006355regulation of transcription, DNA-templated-IDA11782478  15261140  
GO:0006357regulation of transcription by RNA polymerase II-IBA21873635  
GO:0006366transcription by RNA polymerase II-IMP24048733  
GO:0006879cellular iron ion homeostasis-IEA-  
GO:0007165signal transduction-IMP12411310  
GO:0007595lactation-IEA-  
GO:0008542visual learning-IEA-  
GO:0010039response to iron ion-IEP28296633  
GO:0010468regulation of gene expression-IDA18419598  
GO:0010573vascular endothelial growth factor production-IDA12958148  
GO:0010575positive regulation of vascular endothelial growth factor production-IDA8756616  
GO:0010575positive regulation of vascular endothelial growth factor production-IMP18658046  
GO:0010628positive regulation of gene expression-IDA15459207  24244340  
GO:0010628positive regulation of gene expression-IMP21817107  22886504  
GO:0010629negative regulation of gene expression-IMP26879375  
GO:0010634positive regulation of epithelial cell migration-ISS18037992  
GO:0010870positive regulation of receptor biosynthetic process-IMP17178876  
GO:0014850response to muscle activity-IEA-  
GO:0016239positive regulation of macroautophagy-IEA-  
GO:0016579protein deubiquitination-TAS-  
GO:0019221cytokine-mediated signaling pathway-TAS-  
GO:0019896axonal transport of mitochondrion-IMP19528298  
GO:0021502neural fold elevation formation-IEA-  
GO:0021987cerebral cortex development-IEA-  
GO:0030502negative regulation of bone mineralization-IEA-  
GO:0030949positive regulation of vascular endothelial growth factor receptor signaling pathway-IC8756616  12958148  
GO:0032007negative regulation of TOR signaling-IEA-  
GO:0032364oxygen homeostasis-IDA16956324  
GO:0032722positive regulation of chemokine production-TAS18370914  
GO:0032909regulation of transforming growth factor beta2 production-IMP12411310  
GO:0032963collagen metabolic process-ISS18037992  
GO:0035162embryonic hemopoiesis-IEA-  
GO:0035774positive regulation of insulin secretion involved in cellular response to glucose stimulus-IEA-  
GO:0042541hemoglobin biosynthetic process-IEA-  
GO:0042593glucose homeostasis-IEA-  
GO:0042789mRNA transcription by RNA polymerase II-IC7539918  
GO:0043536positive regulation of blood vessel endothelial cell migration-IMP26879375  
GO:0043619regulation of transcription from RNA polymerase II promoter in response to oxidative stress-IDA8089148  8387214  
GO:0043687post-translational protein modification-TAS-  
GO:0045648positive regulation of erythrocyte differentiation-IC1448077  
GO:0045766positive regulation of angiogenesis-IC8756616  
GO:0045766positive regulation of angiogenesis-IMP24048733  26879375  
GO:0045821positive regulation of glycolytic process-IC8089148  
GO:0045893positive regulation of transcription, DNA-templated-IDA8089148  9887100  
GO:0045893positive regulation of transcription, DNA-templated-IMP21056661  
GO:0045926negative regulation of growth-IEA-  
GO:0045944positive regulation of transcription by RNA polymerase II-IBA21873635  
GO:0045944positive regulation of transcription by RNA polymerase II-IDA11573933  25043030  
GO:0045944positive regulation of transcription by RNA polymerase II-IGI9576906  17981124  
GO:0046716muscle cell cellular homeostasis-IEA-  
GO:0046886positive regulation of hormone biosynthetic process-IDA1448077  
GO:0048546digestive tract morphogenesis-IEA-  
GO:0051000positive regulation of nitric-oxide synthase activity-TAS18254728  
GO:0051216cartilage development-IEA-  
GO:0051541elastin metabolic process-ISS18037992  
GO:0060574intestinal epithelial cell maturation-IEA-  
GO:0061030epithelial cell differentiation involved in mammary gland alveolus development-IEA-  
GO:0061072iris morphogenesis-IEA-  
GO:0061298retina vasculature development in camera-type eye-IEA-  
GO:0061418regulation of transcription from RNA polymerase II promoter in response to hypoxia-TAS-  
GO:0061419positive regulation of transcription from RNA polymerase II promoter in response to hypoxia-IDA22735262  
GO:0061419positive regulation of transcription from RNA polymerase II promoter in response to hypoxia-IMP19652095  24681946  
GO:0070101positive regulation of chemokine-mediated signaling pathway-IC17178876  
GO:0070244negative regulation of thymocyte apoptotic process-IEA-  
GO:0071347cellular response to interleukin-1-IEP12958148  
GO:0071456cellular response to hypoxia-IDA11573933  19528298  20889502  
GO:0071456cellular response to hypoxia-IEP20810912  
GO:0071542dopaminergic neuron differentiation-IEA-  
GO:0097411hypoxia-inducible factor-1alpha signaling pathway-IEA-  
GO:1902895positive regulation of pri-miRNA transcription by RNA polymerase II-IMP24983504  
GO:1903377negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway-IDA24899725  
GO:1903599positive regulation of autophagy of mitochondrion-IEA-  
GO:1903715regulation of aerobic respiration-IEA-  
GO:2000378negative regulation of reactive oxygen species metabolic process-IEA-  
GO:2001054negative regulation of mesenchymal cell apoptotic process-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO:0005634nucleus-IBA21873635  
GO:0005634nucleus-IDA8089148  15261140  18658046  20810912  20972335  22848707  24048733  25043030  
GO:0005654nucleoplasm-IDA-  
GO:0005654nucleoplasm-TAS-  
GO:0005667transcription factor complex-IPI9576906  
GO:0005737cytoplasm-IDA19651758  24048733  
GO:0005829cytosol-IDA24681946  
GO:0005829cytosol-TAS-  
GO:0016604nuclear body-IDA-  
GO:0016607nuclear speck-ISS-  
GO:0031514motile cilium-IEA-  
GO:0032991protein-containing complex-IMP14594809  15629713  
GO:0090575RNA polymerase II transcription factor complex-IDA7539918  8756616  
GO:1904115axon cytoplasm-IEA-  
KEGG ID KEGG Term
hsa04150mTOR signaling pathway
hsa05200Pathways in cancer
hsa05211Renal cell carcinoma
Reactome ID Reactome Term Evidence
R-HSA-1234158Regulation of gene expression by Hypoxia-inducible FactorTAS
R-HSA-1234162Oxygen-dependent asparagine hydroxylation of Hypoxia-inducible Factor AlphaTAS
R-HSA-1234174Regulation of Hypoxia-inducible Factor (HIF) by oxygenTAS
R-HSA-1234176Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor AlphaTAS
R-HSA-1280215Cytokine Signaling in Immune systemTAS
R-HSA-157118Signaling by NOTCHIEA
R-HSA-162582Signal TransductionTAS
R-HSA-162582Signal TransductionIEA
R-HSA-168256Immune SystemTAS
R-HSA-1980143Signaling by NOTCH1IEA
R-HSA-2122947NOTCH1 Intracellular Domain Regulates TranscriptionIEA
R-HSA-2262749Cellular response to hypoxiaTAS
R-HSA-2262752Cellular responses to stressTAS
R-HSA-392499Metabolism of proteinsTAS
R-HSA-400253Circadian ClockIEA
R-HSA-449147Signaling by InterleukinsTAS
R-HSA-5688426DeubiquitinationTAS
R-HSA-5689880Ub-specific processing proteasesTAS
R-HSA-597592Post-translational protein modificationTAS
R-HSA-6785807Interleukin-4 and 13 signalingTAS
R-HSA-8848021Signaling by PTK6TAS
R-HSA-8849473PTK6 ExpressionTAS
R-HSA-8857538PTK6 promotes HIF1A stabilizationTAS
R-HSA-8951664NeddylationTAS
R-HSA-8953897Cellular responses to external stimuliTAS
R-HSA-9006927Signaling by Non-Receptor Tyrosine KinasesTAS

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
28683299Effectiveness and feasibility of nailfold microcirculation test to screen for diabetic peripheral neuropathy. (2017 Sep)Hu GDiabetes Res Clin Pract
27981753Association between genetic polymorphisms involved in the hypoxia-inducible factor pathway and lung cancer risk: a case-control study in Japan. (2017 Jun)Yamamoto YAsia Pac J Clin Oncol
20926496Polymorphisms of the hypoxia-inducible factor 1 gene and peripheral artery disease. (2010 Oct)Bahadori BVasc Med
20059631A multilocus candidate approach identifies ACE and HIF1A as susceptibility genes for cellulite. (2010 Aug)Emanuele EJ Eur Acad Dermatol Venereol
27279347A systems biology and proteomics-based approach identifies SRC and VEGFA as biomarkers in risk factor mediated coronary heart disease. (2016 Jul 19)V AMol Biosyst
22531693Oxidative balance and colon and rectal cancer: interaction of lifestyle factors and genes. (2012 Jun 1)Slattery MLMutat Res
23421024[Gene-environment interaction for the HIF1-A 1772C>T polymorphisms and cigarette smoking increase susceptibility to abdominal aortic aneurysm]. (2012)Strauss EPrzegl Lek
25165809Effects of maternal smoking on the placental expression of genes related to angiogenesis and apoptosis during the first trimester. (2014)Kawashima APLoS One
22012259A SUMOylation-defective MITF germline mutation predisposes to melanoma and renal carcinoma. (2011 Oct 19)Bertolotto CNature