Gene info: ID 3159

Gene: HMGA1

GENE ID: 3159

Synonyms: HMG-R|HMGA1A|HMGIY

Description: high mobility group AT-hook 1

Gene type: protein-coding

Location: 6p21.31

dbXrefs: Ensembl:ENSG00000137309 MIM:600701 Vega:OTTHUMG00000014539 UniprotKB:P17096

RefSeq: NG_029020.1

Retrived from: PubMed

SNPs: 0 ANCO-SNPs

Phenotype: ND

# Publications: 2

Sherlock p-value : NA (AD) NA (ND) (Frontal_Cortex)

Pascal p-value : 3.249e-1 (AD) 1.966e-1 (ND)

DNA Methylation

Probe	Locus(GRCh37)	Gene	Region	p-val	Trait	PubMed ID
cg10167849	chr6:34206152	HMGA1	Promoter	4.491e-4	Alcohol use disorders	26763658
cg02654940	chr6:34206400	HMGA1		1.900e-18	Smoking	27651444
cg22797644	chr6:34206491	HMGA1		4.500e-9	Smoking	27651444
cg02654940	chr6:34206400	HMGA1		1.450e-9	Alcohol consumption der day	27843151
cg08335767	chr6:34206495	HMGA1		4.750e-9	Alcohol consumption der day	27843151
cg22797644	chr6:34206491	HMGA1		2.570e-11	Alcohol consumption der day	27843151

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol	Pearson Correlation Coefficient
USB1	0.889
ARHGDIA	0.889
FNDC4	0.889
NTMT1	0.875
LRRC59	0.869
SNAPC2	0.868
ARPC2	0.867
PSMD8	0.866
ALKBH5	0.865
ARPC5L	0.864

Top 10 negatively co-expressed genes

Gene Symbol	Pearson Correlation Coefficient
OR4F5	-0.679
OR4F29	-0.624
P2RY14	-0.336
VNN3	-0.296
PARD3B	-0.283
ASB4	-0.269
PON3	-0.259
MBNL3	-0.258
CTNNA3	-0.258
OLAH	-0.253

There is no DrugBank record for this gene !

ID	Drug Name	Action	PubMed
C029790	2,2',3',4,4',5-hexachlorobiphenyl	"[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in decreased expression of HMGA1 mRNA"	25510870
C014211	2,3,7,8-tetrachlorodibenzofuran	"2,3,7,8-tetrachlorodibenzofuran affects the expression of HMGA1 mRNA"	20702594
C029497	2,3-bis(3'-hydroxybenzyl)butyrolactone	"[Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of HMGA1 mRNA"	19167446
C063002	2,3-dimethoxy-1,4-naphthoquinone	"2,3-dimethoxy-1,4-naphthoquinone results in increased expression of HMGA1 mRNA"	17547211
C081766	2,4,4'-trichlorobiphenyl	"[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in decreased expression of HMGA1 mRNA"	25510870
C014024	2,4,5,2',4',5'-hexachlorobiphenyl	"2,4,5,2',4',5'-hexachlorobiphenyl results in increased activity of HMGA1 protein"	27589886
C014024	2,4,5,2',4',5'-hexachlorobiphenyl	"[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in decreased expression of HMGA1 mRNA"	25510870
C009828	2,4,5,2',5'-pentachlorobiphenyl	"[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in decreased expression of HMGA1 mRNA"	25510870
C010914	2,4-diaminotoluene	"2,4-diaminotoluene results in increased expression of HMGA1 mRNA"	20713471
C009407	2,5,2',5'-tetrachlorobiphenyl	"[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in decreased expression of HMGA1 mRNA"	25510870
C002010	4-(2-aminoethyl)benzenesulfonylfluoride	4-(2-aminoethyl)benzenesulfonylfluoride inhibits the reaction [[Estradiol co-treated with Progesterone] results in decreased expression of HMGA1 mRNA]	20660070
C009505	4,4'-diaminodiphenylmethane	"4,4'-diaminodiphenylmethane results in decreased expression of HMGA1 mRNA"	18648102
C027576	4-hydroxy-2-nonenal	4-hydroxy-2-nonenal results in decreased expression of HMGA1 mRNA	12419474
C075773	4-phenylbutyric acid	4-phenylbutyric acid results in decreased expression of HMGA1 mRNA	14583596
D000082	Acetaminophen	Acetaminophen results in increased expression of HMGA1 mRNA	29067470
D020106	Acrylamide	Acrylamide results in increased expression of HMGA1 mRNA	28959563
D016604	Aflatoxin B1	Aflatoxin B1 results in increased expression of HMGA1 mRNA	22100608
C077990	alvocidib	alvocidib results in decreased expression of HMGA1 mRNA	21239698
D000643	Ammonium Chloride	Ammonium Chloride affects the expression of HMGA1 mRNA	16483693
D000965	Antimony	Antimony results in increased expression of HMGA1 mRNA	17547211
D000966	Antimony Potassium Tartrate	Antimony Potassium Tartrate results in increased expression of HMGA1 mRNA	17547211
C006632	arsenic trioxide	arsenic trioxide results in increased expression of HMGA1 mRNA	17547211
D017638	Asbestos, Crocidolite	"Asbestos, Crocidolite affects the expression of HMGA1 mRNA"	17331233
D017638	Asbestos, Crocidolite	"Asbestos, Crocidolite results in increased expression of HMGA1 mRNA"	12839939
D017638	Asbestos, Crocidolite	"Asbestos, Crocidolite results in increased expression of HMGA1 mRNA"	12839939
D001374	Azacitidine	Azacitidine results in increased expression of HMGA1 mRNA	20823114
C006703	benzo(b)fluoranthene	benzo(b)fluoranthene results in increased expression of HMGA1 mRNA	26377693
C022921	benzo(k)fluoranthene	benzo(k)fluoranthene results in decreased expression of HMGA1 mRNA	26377693
D001564	Benzo(a)pyrene	Benzo(a)pyrene results in decreased expression of HMGA1 mRNA	19770486
D001564	Benzo(a)pyrene	Benzo(a)pyrene results in increased expression of HMGA1 mRNA	22228805
D004958	Estradiol	4-(2-aminoethyl)benzenesulfonylfluoride inhibits the reaction [[Estradiol co-treated with Progesterone] results in decreased expression of HMGA1 mRNA]	20660070
D004958	Estradiol	[Estradiol co-treated with Progesterone] results in decreased expression of HMGA1 mRNA	20660070
D004958	Estradiol	Estradiol results in increased expression of HMGA1 mRNA	23019147
D004958	Estradiol	N-(2(R)-2-(hydroxamidocarbonylmethyl)-4-methylpentanoyl)-L-tryptophan methylamide inhibits the reaction [[Estradiol co-treated with Progesterone] results in decreased expression of HMGA1 mRNA]	20660070
D004958	Estradiol	pepstatin inhibits the reaction [[Estradiol co-treated with Progesterone] results in decreased expression of HMGA1 mRNA]	20660070
C543008	bis(4-hydroxyphenyl)sulfone	[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in decreased expression of HMGA1 mRNA	28628672
C006780	bisphenol A	[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of HMGA1 mRNA	28628672
C006780	bisphenol A	bisphenol A affects the methylation of HMGA1 promoter	27334623
C006780	bisphenol A	bisphenol A results in decreased expression of HMGA1 mRNA	26063408
C006780	bisphenol A	bisphenol A affects the expression of HMGA1 mRNA	25181051
C013418	bromfenacoum	bromfenacoum results in increased expression of HMGA1 protein	28903499
D015124	8-Bromo Cyclic Adenosine Monophosphate	8-Bromo Cyclic Adenosine Monophosphate results in increased expression of HMGA1 mRNA	22079614
C515564	bromovanin	bromovanin results in increased expression of HMGA1 protein	21419150
D020122	tert-Butylhydroperoxide	tert-Butylhydroperoxide results in decreased expression of HMGA1 mRNA	12419474
D020122	tert-Butylhydroperoxide	tert-Butylhydroperoxide results in increased expression of HMGA1 mRNA	15336504
C584509	C646 compound	C646 compound results in decreased expression of HMGA1 mRNA	26191083
D019256	Cadmium Chloride	Cadmium Chloride results in increased expression of HMGA1 mRNA	12160620
D019256	Cadmium Chloride	Cadmium Chloride results in decreased methylation of HMGA1 promoter	22457795
D002857	Chromium	Chromium results in increased expression of HMGA1 mRNA	17547211
D002994	Clofibrate	Clofibrate results in decreased expression of HMGA1 mRNA	23811191
D003042	Cocaine	Cocaine affects the expression of HMGA1 mRNA	20187946
D003300	Copper	[ATP7A gene mutant form results in increased abundance of Copper] which results in decreased expression of HMGA1 mRNA	15467011
D019327	Copper Sulfate	Copper Sulfate results in increased expression of HMGA1 mRNA	19549813
D003375	Coumestrol	"[Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of HMGA1 mRNA"	19167446
D016572	Cyclosporine	Cyclosporine results in increased expression of HMGA1 mRNA	25562108\|2798913
D003907	Dexamethasone	[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in decreased expression of HMGA1 mRNA	28628672
D003907	Dexamethasone	[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of HMGA1 mRNA	28628672
D002945	Cisplatin	Cisplatin results in decreased expression of HMGA1 mRNA	27594783
D002945	Cisplatin	Cisplatin results in increased expression of HMGA1 mRNA	21151649
D002945	Cisplatin	Cisplatin results in increased phosphorylation of HMGA1 protein	22006019
D004054	Diethylstilbestrol	Diethylstilbestrol results in increased expression of HMGA1 mRNA	17394237
D004128	Dimethylnitrosamine	Dimethylnitrosamine results in increased expression of HMGA1 mRNA	17547211
C045651	epigallocatechin gallate	[potassium chromate(VI) co-treated with epigallocatechin gallate] results in increased expression of HMGA1 mRNA	22079256
D005020	Ethyl Methanesulfonate	Ethyl Methanesulfonate results in decreased expression of HMGA1 mRNA	23649840
D005411	Flame Retardants	Flame Retardants results in increased expression of HMGA1 mRNA	27219277
D005557	Formaldehyde	Formaldehyde results in decreased expression of HMGA1 mRNA	23649840\|2893796
D005944	Glucosamine	Glucosamine results in increased expression of HMGA1 mRNA	17109745
C412815	GW 4064	GW 4064 promotes the reaction [NR1H4 protein binds to HMGA1 gene]	20091679
D055768	Halogenated Diphenyl Ethers	Halogenated Diphenyl Ethers results in increased expression of HMGA1 mRNA	27219277
D017313	Fenretinide	Fenretinide results in increased expression of HMGA1 mRNA	28973697
D006861	Hydrogen Peroxide	Hydrogen Peroxide results in decreased expression of HMGA1 mRNA	12419474
C492448	ICG 001	ICG 001 results in decreased expression of HMGA1 mRNA	26191083
D007213	Indomethacin	[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in decreased expression of HMGA1 mRNA	28628672
D007213	Indomethacin	[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of HMGA1 mRNA	28628672
D015056	1-Methyl-3-isobutylxanthine	[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in decreased expression of HMGA1 mRNA	28628672
D015056	1-Methyl-3-isobutylxanthine	[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of HMGA1 mRNA	28628672
C544151	jinfukang	jinfukang results in increased expression of HMGA1 mRNA	27392435
D008694	Methamphetamine	Methamphetamine results in increased expression of HMGA1 mRNA	25290377
D008694	Methamphetamine	[Methamphetamine co-treated with SCH 23390] results in increased expression of HMGA1 mRNA	19564919
D008694	Methamphetamine	Methamphetamine results in increased expression of HMGA1 mRNA	19564919
D008748	Methylcholanthrene	Methylcholanthrene results in increased expression of HMGA1 mRNA	20713471
D008767	Methylmercury Compounds	Methylmercury Compounds results in increased expression of HMGA1 mRNA	22918959
D008741	Methyl Methanesulfonate	Methyl Methanesulfonate results in decreased expression of HMGA1 mRNA	23649840
D016685	Mitomycin	HMGA1 protein affects the susceptibility to Mitomycin	16217747
C078131	N-(2(R)-2-(hydroxamidocarbonylmethyl)-4-methylpentanoyl)-L-tryptophan methylamide	N-(2(R)-2-(hydroxamidocarbonylmethyl)-4-methylpentanoyl)-L-tryptophan methylamide inhibits the reaction [[Estradiol co-treated with Progesterone] results in decreased expression of HMGA1 mRNA]	20660070
D037742	Nanotubes, Carbon	"Nanotubes, Carbon analog results in increased expression of HMGA1 mRNA"	25554681
D037742	Nanotubes, Carbon	"Nanotubes, Carbon results in increased expression of HMGA1 mRNA"	25554681
C017096	n-butoxyethanol	n-butoxyethanol results in decreased expression of HMGA1 mRNA	19812364
D009538	Nicotine	Nicotine results in decreased expression of HMGA1 mRNA	16949557
C014707	nitrosobenzylmethylamine	[Zinc deficiency promotes the reaction [TRP53 gene mutant form results in increased susceptibility to nitrosobenzylmethylamine]] which results in increased expression of HMGA1 mRNA	12517797
C410127	PCB 180	"[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in decreased expression of HMGA1 mRNA"	25510870
C086401	pentabromodiphenyl ether	pentabromodiphenyl ether results in increased expression of HMGA1 mRNA	26705709
C031375	pepstatin	pepstatin inhibits the reaction [[Estradiol co-treated with Progesterone] results in decreased expression of HMGA1 mRNA]	20660070
C023036	perfluorooctanoic acid	perfluorooctanoic acid results in increased activity of HMGA1 protein	27589886
C006253	pirinixic acid	pirinixic acid results in increased expression of HMGA1 mRNA	23811191
D010936	Plant Extracts	Plant Extracts results in decreased expression of HMGA1 mRNA	23557933
C027373	potassium chromate(VI)	[potassium chromate(VI) co-treated with epigallocatechin gallate] results in increased expression of HMGA1 mRNA	22079256
C027373	potassium chromate(VI)	potassium chromate(VI) results in increased expression of HMGA1 mRNA	22079256
D011192	Potassium Dichromate	Potassium Dichromate results in increased expression of HMGA1 mRNA	17547211
D011374	Progesterone	Progesterone results in decreased expression of HMGA1 mRNA	23018184
D011374	Progesterone	4-(2-aminoethyl)benzenesulfonylfluoride inhibits the reaction [[Estradiol co-treated with Progesterone] results in decreased expression of HMGA1 mRNA]	20660070
D011374	Progesterone	[Estradiol co-treated with Progesterone] results in decreased expression of HMGA1 mRNA	20660070
D011374	Progesterone	N-(2(R)-2-(hydroxamidocarbonylmethyl)-4-methylpentanoyl)-L-tryptophan methylamide inhibits the reaction [[Estradiol co-treated with Progesterone] results in decreased expression of HMGA1 mRNA]	20660070
D011374	Progesterone	pepstatin inhibits the reaction [[Estradiol co-treated with Progesterone] results in decreased expression of HMGA1 mRNA]	20660070
D011374	Progesterone	Progesterone results in decreased expression of HMGA1 mRNA	17404688\|2066007
D011374	Progesterone	Progesterone results in decreased expression of HMGA1 mRNA	22238285
D011794	Quercetin	Quercetin results in increased expression of HMGA1 mRNA	21632981
C534628	SCH 23390	[Methamphetamine co-treated with SCH 23390] results in increased expression of HMGA1 mRNA	19564919
D012822	Silicon Dioxide	Silicon Dioxide analog results in increased expression of HMGA1 mRNA	25895662
D012999	Soman	Soman results in increased expression of HMGA1 mRNA	19281266
C020806	tetrabromobisphenol A	tetrabromobisphenol A results in increased expression of HMGA1 mRNA	25172293
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin affects the expression of HMGA1 mRNA	20702594
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin results in decreased expression of HMGA1 mRNA	24058054
C014215	tetrahydropalmatine	tetrahydropalmatine results in decreased expression of HMGA1 protein	20109541
D013849	Thimerosal	Thimerosal results in decreased expression of HMGA1 mRNA	27188386
D019772	Topotecan	HMGA1 protein affects the susceptibility to Topotecan	16217747
D014118	Toxins, Biological	"Toxins, Biological affects the expression of HMGA1 mRNA"	19682533
C496197	trans-10,cis-12-conjugated linoleic acid	"trans-10,cis-12-conjugated linoleic acid results in increased expression of HMGA1 mRNA"	17951470
C015559	trimellitic anhydride	trimellitic anhydride results in increased expression of HMGA1 mRNA	19042947
C016805	tris(1,3-dichloro-2-propyl)phosphate	"tris(1,3-dichloro-2-propyl)phosphate results in increased expression of HMGA1 mRNA"	26179874
D014635	Valproic Acid	Valproic Acid results in increased methylation of HMGA1 gene	29154799
D014640	Vancomycin	Vancomycin results in decreased expression of HMGA1 mRNA	18930951
D015032	Zinc	[Zinc deficiency promotes the reaction [TRP53 gene mutant form results in increased susceptibility to nitrosobenzylmethylamine]] which results in increased expression of HMGA1 mRNA	12517797

GO/Pathway

GO ID	GO Term	Qualifier	Evidence	PubMed
GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding	-	ISA	-
GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding	-	ISM	19274049
GO:0001158	enhancer sequence-specific DNA binding	-	IDA	9253416
GO:0001205	transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific DNA binding	-	ISS	-
GO:0003677	DNA binding	-	TAS	10871404
GO:0003680	AT DNA binding	-	IDA	9253416
GO:0003680	AT DNA binding	-	ISS	-
GO:0003680	AT DNA binding	-	TAS	10428834
GO:0003682	chromatin binding	-	ISS	-
GO:0003700	DNA-binding transcription factor activity	-	IBA	21873635
GO:0003906	DNA-(apurinic or apyrimidinic site) endonuclease activity	-	IBA	21873635
GO:0005515	protein binding	-	IPI	10428834 12665574 18234858
GO:0008134	transcription factor binding	-	IDA	10428834
GO:0019899	enzyme binding	-	IPI	16157300
GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity	-	IMP	10428834
GO:0042974	retinoic acid receptor binding	-	IDA	10428834
GO:0042975	peroxisome proliferator activated receptor binding	-	IDA	10428834
GO:0046965	retinoid X receptor binding	-	IDA	10428834

GO ID	GO Term	Qualifier	Evidence	PubMed
GO:0006268	DNA unwinding involved in DNA replication	-	NAS	10428834
GO:0006284	base-excision repair	-	IBA	21873635
GO:0006337	nucleosome disassembly	-	TAS	10428834
GO:0006355	regulation of transcription, DNA-templated	-	IBA	21873635
GO:0006355	regulation of transcription, DNA-templated	-	TAS	10871404
GO:0006366	transcription by RNA polymerase II	-	IEA	-
GO:0008285	negative regulation of cell proliferation	-	IMP	16901784
GO:0009615	response to virus	-	IEP	17005673
GO:0031936	negative regulation of chromatin silencing	-	TAS	10428834
GO:0035986	senescence-associated heterochromatin focus assembly	-	IDA	16901784
GO:0045892	negative regulation of transcription, DNA-templated	-	IMP	16901784
GO:0045893	positive regulation of transcription, DNA-templated	-	IMP	10428834
GO:0045944	positive regulation of transcription by RNA polymerase II	-	ISS	-
GO:0051169	nuclear transport	-	TAS	-
GO:0065003	protein-containing complex assembly	-	TAS	10428834
GO:0075713	establishment of integrated proviral latency	-	TAS	-
GO:0090402	oncogene-induced cell senescence	-	IDA	16901784
GO:2000774	positive regulation of cellular senescence	-	IMP	16901784

GO ID	GO Term	Qualifier	Evidence	PubMed
GO:0005634	nucleus	-	HDA	16791210
GO:0005634	nucleus	-	IBA	21873635
GO:0005634	nucleus	-	IDA	16901784
GO:0005654	nucleoplasm	-	TAS	-
GO:0005667	transcription factor complex	-	TAS	10428834
GO:0005829	cytosol	-	TAS	-
GO:0005925	focal adhesion	-	HDA	21423176
GO:0035985	senescence-associated heterochromatin focus	-	IDA	16901784
GO:0090575	RNA polymerase II transcription factor complex	-	ISS	-

KEGG ID	KEGG Term

Reactome ID	Reactome Term	Evidence
R-HSA-162587	HIV Life Cycle	TAS
R-HSA-162592	Integration of provirus	TAS
R-HSA-162594	Early Phase of HIV Life Cycle	TAS
R-HSA-162906	HIV Infection	TAS
R-HSA-162909	Host Interactions of HIV factors	TAS
R-HSA-1643685	Disease	TAS
R-HSA-164843	2-LTR circle formation	TAS
R-HSA-175567	Integration of viral DNA into host genomic DNA	TAS
R-HSA-176033	Interactions of Vpr with host cellular proteins	TAS
R-HSA-177539	Autointegration results in viral DNA circles	TAS
R-HSA-180689	APOBEC3G mediated resistance to HIV-1 infection	TAS
R-HSA-180910	Vpr-mediated nuclear import of PICs	TAS
R-HSA-2262752	Cellular responses to stress	TAS
R-HSA-2559583	Cellular Senescence	TAS
R-HSA-2559584	Formation of Senescence-Associated Heterochromatin Foci (SAHF)	TAS
R-HSA-2559586	DNA Damage/Telomere Stress Induced Senescence	TAS
R-HSA-5663205	Infectious disease	TAS
R-HSA-8953897	Cellular responses to external stimuli	TAS

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID	Title (Year)	Author	Journal
24121172	Endobronchial lipomatous tumors: clinicopathologic analysis of 12 cases with molecular cytogenetic evidence supporting classification as "lipoma". (2013 Nov)	Boland JM	Am J Surg Pathol
23978819	Generalization of adiposity genetic loci to US Hispanic women. (2013 Aug 26)	Graff M	Nutr Diabetes