Gene: NR4A1

3164
GFRP1|HMR|N10|NAK-1|NGFIB|NP10|NUR77|TR3
nuclear receptor subfamily 4 group A member 1
protein-coding
12q13.13
Ensembl:ENSG00000123358 MIM:139139 Vega:OTTHUMG00000150393 UniprotKB:P22736
NC_000012.12
PubMed
0   ANCO-SNPs
ND
1   
NA (AD)  NA (ND)   (Frontal_Cortex)
9.790e-1 (AD)  2.842e-1 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
EGR10.828
KLF40.761
FOS0.755
SIK10.736
DUSP10.736
DUSP50.734
JUNB0.733
CYR610.716
NR4A20.699
IER20.697

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
MEIG1-0.309
OXTR-0.267
MORN5-0.266
GMNN-0.249
FXYD3-0.246
KLF15-0.245
SLC14A1-0.243
MIA-0.24
KLHL1-0.232
RFTN2-0.231

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C5525301,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane"1,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane inhibits the reaction [NR4A1 protein binds to TXNDC5 promoter]"24515801
C5525301,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane"1,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane inhibits the reaction [TGFB1 protein affects the localization of NR4A1 protein]"26929200
C5525301,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane"1,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane inhibits the reaction [TGFB1 protein promotes the reaction [NR4A1 protein binds to AXIN2 protein]]"26929200
C5525301,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane"NR4A1 protein inhibits the reaction [1,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane results in decreased expression of BIRC5 mRNA]"20660371
C5525301,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane"NR4A1 protein inhibits the reaction [1,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane results in increased cleavage of CASP3 protein]"20660371
C5525301,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane"NR4A1 protein inhibits the reaction [1,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane results in increased cleavage of CASP8 protein]"24515801
C5525301,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane"NR4A1 protein inhibits the reaction [1,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane results in increased cleavage of PARP1 protein]"20660371|2451580
C5525301,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane"NR4A1 protein inhibits the reaction [1,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane results in increased expression of ATF4 protein]"24515801
C5525301,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane"NR4A1 protein inhibits the reaction [1,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane results in increased expression of BCL2 protein]"20660371
C5525301,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane"NR4A1 protein inhibits the reaction [1,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane results in increased expression of BIRC5 protein]"20660371
C5525301,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane"NR4A1 protein inhibits the reaction [1,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane results in increased expression of DDIT3 protein]"24515801
C5525301,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane"NR4A1 protein inhibits the reaction [1,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane results in increased expression of XBP1 protein alternative form]"24515801
C5525301,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane"NR4A1 protein results in increased susceptibility to 1,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane"26035713|2692920
C0512461-methylanthracene[1-methylanthracene co-treated with fluoranthene] results in increased expression of NR4A1 mRNA28329830
C0512461-methylanthraceneSB 203580 inhibits the reaction [[1-methylanthracene co-treated with fluoranthene] results in increased expression of NR4A1 mRNA]28329830
C5112952,2',4,4'-tetrabromodiphenyl ether"2,2',4,4'-tetrabromodiphenyl ether results in increased expression of NR4A1 mRNA"25614096
C5112952,2',4,4'-tetrabromodiphenyl ether"2,2',4,4'-tetrabromodiphenyl ether analog results in increased expression of NR4A1 mRNA"19095052
C0354762,2',4,4'-tetrahydroxybenzophenone"2,2',4,4'-tetrahydroxybenzophenone inhibits the reaction [Triiodothyronine inhibits the reaction [[NR4A1 co-treated with THRA] results in increased expression of HSD3B1 mRNA]]"21726595
C0354762,2',4,4'-tetrahydroxybenzophenone"2,2',4,4'-tetrahydroxybenzophenone inhibits the reaction [Triiodothyronine inhibits the reaction [[NR4A1 co-treated with THRA] results in increased expression of STAR mRNA]]"21726595
C0354762,2',4,4'-tetrahydroxybenzophenone"2,2',4,4'-tetrahydroxybenzophenone inhibits the reaction [Triiodothyronine promotes the reaction [[NR4A1 co-treated with THRA] results in increased expression of HSD3B1 mRNA]]"21726595
C0354762,2',4,4'-tetrahydroxybenzophenone"2,2',4,4'-tetrahydroxybenzophenone promotes the reaction [[NR4A1 co-treated with THRA] results in increased expression of HSD3B1 mRNA]"21726595
C0354762,2',4,4'-tetrahydroxybenzophenone"2,2',4,4'-tetrahydroxybenzophenone promotes the reaction [[NR4A1 co-treated with THRA] results in increased expression of STAR mRNA]"21726595
C0291412,2,5,7,8-pentamethyl-1-hydroxychroman"2,2,5,7,8-pentamethyl-1-hydroxychroman results in decreased expression of NR4A1 mRNA"21920950
C0939732-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [cadmium acetate results in increased expression of NR4A1 protein]15016657
C0939732-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [bisphenol A results in increased expression of NR4A1 mRNA]12021184
C0192732,2-bis(4-glycidyloxyphenyl)propane"2,2-bis(4-glycidyloxyphenyl)propane results in increased expression of NR4A1 mRNA"18525235
C0192732,2-bis(4-glycidyloxyphenyl)propane"2,2-bis(4-glycidyloxyphenyl)propane results in increased expression of NR4A1 protein"18525235
C0192732,2-bis(4-glycidyloxyphenyl)propane"NR4A1 protein promotes the reaction [2,2-bis(4-glycidyloxyphenyl)propane affects the abundance of Progesterone]"18525235
C4049102,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane"2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane results in increased expression of NR4A1 mRNA"20826375
C1111182',3,3',4',5-pentachloro-4-hydroxybiphenyl"2',3,3',4',5-pentachloro-4-hydroxybiphenyl results in decreased expression of NR4A1 mRNA"19114083
C0087454,4'-bisphenol F"4,4'-bisphenol F results in increased expression of NR4A1 mRNA"26186136
C5830744,4'-hexafluorisopropylidene diphenol"4,4'-hexafluorisopropylidene diphenol results in increased expression of NR4A1 mRNA"27567155
C4053544,5,6,7-tetrabromobenzotriazole"4,5,6,7-tetrabromobenzotriazole inhibits the reaction [BDNF protein promotes the reaction [BRD4 protein binds to NR4A1 promoter]]"26301327
C4053544,5,6,7-tetrabromobenzotriazole"4,5,6,7-tetrabromobenzotriazole inhibits the reaction [BDNF protein results in increased expression of NR4A1 mRNA]"26301327
C0275764-hydroxy-2-nonenal4-hydroxy-2-nonenal results in decreased expression of NR4A1 mRNA19191707
D000079AcetaldehydeAcetaldehyde results in increased expression of NR4A1 mRNA23416264
D000082AcetaminophenAcetaminophen results in increased expression of NR4A1 mRNA29067470
D000082AcetaminophenAcetaminophen affects the expression of NR4A1 mRNA17562736
D000082AcetaminophenAcetaminophen results in increased expression of NR4A1 mRNA11264010
D000171AcroleinAcrolein results in increased expression of NR4A1 mRNA20015449
D000171AcroleinAcrolein results in increased expression of NR4A1 protein20015449
D020106AcrylamideAcrylamide results in decreased expression of NR4A1 mRNA22197712|2895956
D000255Adenosine TriphosphateAdenosine Triphosphate results in increased expression of NR4A1 mRNA10723097
C016601afimoxifeneafimoxifene results in increased expression of NR4A1 mRNA16514628
D000393Air PollutantsAir Pollutants analog results in increased expression of NR4A1 mRNA21757418
D053959Alpha-AmanitinAlpha-Amanitin inhibits the reaction [LHB protein results in increased expression of NR4A1 mRNA]11416027
D000535Aluminum[APP protein modified form binds to Aluminum] which results in increased expression of NR4A1 mRNA21298039
D000643Ammonium ChlorideAmmonium Chloride affects the expression of NR4A1 mRNA16483693
D003913DextroamphetamineDextroamphetamine results in increased expression of NR4A1 mRNA19194377
D000661AmphetamineAmphetamine promotes the reaction [Ibotenic Acid results in decreased expression of NR4A1 mRNA]14622910
D000661AmphetamineAmphetamine results in decreased expression of NR4A1 mRNA15183010
D000661AmphetamineAmphetamine results in increased expression of NR4A1 mRNA12638131|1462291
D000936Antigen-Antibody ComplexAntigen-Antibody Complex results in increased expression of NR4A1 mRNA25451590
D000936Antigen-Antibody ComplexCyclosporine inhibits the reaction [Antigen-Antibody Complex results in increased expression of NR4A1 mRNA]25451590
D000936Antigen-Antibody Complexshikonin inhibits the reaction [Antigen-Antibody Complex results in increased expression of NR4A1 mRNA]25451590
D001151ArsenicArsenic results in decreased expression of NR4A1 mRNA19654921
C006632arsenic trioxidearsenic trioxide results in decreased expression of NR4A1 mRNA20458559
C015001arsenite[arsenite co-treated with Benzo(a)pyrene] results in decreased expression of NR4A1 mRNA15894712
C015001arsenitearsenite results in decreased expression of NR4A1 mRNA15894712
D017638Asbestos, Crocidolite"Asbestos, Crocidolite affects the expression of NR4A1 mRNA"25757056
D017638Asbestos, Crocidolite"Asbestos, Crocidolite results in increased expression of NR4A1 mRNA"18687144
D001280AtrazineAtrazine results in increased expression of NR4A1 mRNA18461179
D001374Azacitidine[metacept-1 co-treated with Azacitidine] results in increased expression of NR4A119148494
D001507BeclomethasoneBeclomethasone results in increased expression of NR4A1 mRNA23656298
D001554BenzeneBenzene results in decreased expression of NR4A1 mRNA15120971|1512265
D001564Benzo(a)pyreneBenzo(a)pyrene results in decreased expression of NR4A1 mRNA22178795
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of NR4A1 mRNA22316170
D001564Benzo(a)pyrene[arsenite co-treated with Benzo(a)pyrene] results in decreased expression of NR4A1 mRNA15894712
D001564Benzo(a)pyreneBenzo(a)pyrene results in decreased expression of NR4A1 mRNA15894712|2071347
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of NR4A1 mRNA21569818
D0151237,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide"7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased expression of NR4A1 mRNA"26238291
D004958EstradiolEstradiol affects the expression of NR4A1 mRNA23557687
D004958EstradiolEstradiol results in decreased expression of NR4A1 mRNA16514628
D004958EstradiolESR1 protein promotes the reaction [Estradiol results in increased expression of NR4A1 mRNA]20667977
D004958EstradiolEstradiol affects the expression of NR4A1 mRNA15598610
D004958EstradiolEstradiol results in increased expression of NR4A1 mRNA20667977|2082637
D004958EstradiolEstradiol results in decreased expression of NR4A1 mRNA20068009
C543008bis(4-hydroxyphenyl)sulfonebis(4-hydroxyphenyl)sulfone results in increased expression of NR4A1 mRNA26186136
C070515bisindolylmaleimide Ibisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NR4A1 protein]19282384
C006780bisphenol Abisphenol A affects the expression of NR4A1 mRNA21786754
C006780bisphenol Abisphenol A affects the expression of NR4A1 mRNA20170705
C006780bisphenol Abisphenol A results in decreased expression of NR4A1 mRNA27685785
C006780bisphenol Abisphenol A results in increased expression of NR4A1 mRNA24586524
C006780bisphenol A2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [bisphenol A results in increased expression of NR4A1 mRNA]12021184
C006780bisphenol Abisphenol A affects the methylation of NR4A1 promoter27334623
C006780bisphenol Abisphenol A results in decreased expression of NR4A1 mRNA25594700
C006780bisphenol Abisphenol A results in increased expression of NR4A1 mRNA12021184|2082637
C006780bisphenol Abisphenol A results in increased methylation of NR4A1 promoter27312807
C006780bisphenol A[bisphenol A results in increased phosphorylation of and results in increased activity of MAPK1 protein] which results in increased expression of NR4A1 mRNA12021184
C006780bisphenol A[bisphenol A results in increased phosphorylation of and results in increased activity of MAPK3 protein] which results in increased expression of NR4A1 mRNA12021184
C006780bisphenol AJUN protein promotes the reaction [bisphenol A results in increased expression of NR4A1 mRNA]12021184
C006780bisphenol AN-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [bisphenol A results in increased expression of NR4A1 mRNA]12021184
C006780bisphenol ANR4A1 protein mutant form inhibits the reaction [bisphenol A results in increased abundance of Progesterone]12021184
C006780bisphenol ANR4A1 protein promotes the reaction [bisphenol A results in increased abundance of Progesterone]12021184
C006780bisphenol Abisphenol A affects the expression of NR4A1 mRNA25181051
C006780bisphenol Abisphenol A results in increased methylation of NR4A1 gene28505145
C006780bisphenol Abisphenol A results in increased expression of NR4A1 mRNA18525235
C005961bis(tri-n-butyltin)oxidebis(tri-n-butyltin)oxide results in increased expression of NR4A1 mRNA21601586|2424702
C005961bis(tri-n-butyltin)oxidebis(tri-n-butyltin)oxide results in increased expression of NR4A1 protein22613032
C005961bis(tri-n-butyltin)oxidebis(tri-n-butyltin)oxide results in increased expression of NR4A1 mRNA17553608
D0151248-Bromo Cyclic Adenosine Monophosphate8-Bromo Cyclic Adenosine Monophosphate results in increased expression of NR4A1 mRNA22079614
D0151248-Bromo Cyclic Adenosine Monophosphate8-Bromo Cyclic Adenosine Monophosphate results in increased expression of NR4A1 protein21726595
D020122tert-Butylhydroperoxidetert-Butylhydroperoxide results in increased expression of NR4A1 mRNA12414654
C018475butyraldehydebutyraldehyde results in increased expression of NR4A1 mRNA26079696
D002104CadmiumCadmium results in increased expression of NR4A1 mRNA22562489
D002104CadmiumNR4A1 mutant form inhibits the reaction [Cadmium results in increased expression of BAX mRNA]15016657
C028031cadmium acetate2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [cadmium acetate results in increased expression of NR4A1 protein]15016657
C028031cadmium acetatecadmium acetate results in increased expression of and results in increased activity of NR4A1 protein15016657
C028031cadmium acetatecadmium acetate results in increased expression of NR4A1 mRNA15016657
C028031cadmium acetateCyclosporine inhibits the reaction [cadmium acetate results in increased expression of NR4A1 protein]15016657
C028031cadmium acetateN-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [cadmium acetate results in increased expression of NR4A1 protein]15016657
C028031cadmium acetatecadmium acetate results in increased expression of NR4A1 mRNA15016657
C028031cadmium acetatecadmium acetate results in increased expression of NR4A1 protein15016657
D019256Cadmium ChlorideCadmium Chloride results in increased expression of NR4A1 mRNA19010381
C037123cadmium sulfatecadmium sulfate results in increased expression of NR4A1 mRNA21783983
D000001CalcimycinCalcimycin results in increased expression of NR4A1 mRNA25451590
D000001CalcimycinNR4A1 mRNA promotes the reaction [Calcimycin results in increased expression of TNF mRNA]25451590
D000001Calcimycinshikonin inhibits the reaction [Calcimycin results in increased expression of NR4A1 mRNA]25451590
D002251Carbon TetrachlorideCarbon Tetrachloride results in increased expression of NR4A1 mRNA17032414
C010063carbonyl sulfidecarbonyl sulfide affects the expression of NR4A1 mRNA19395590
C099555CD 437CD 437 affects the localization of NR4A1 protein17150035
D002713ChlorineChlorine results in decreased expression of NR4A1 mRNA18636392
D002713Chlorine[Ozone co-treated with Chlorine] affects the expression of NR4A1 mRNA18636392
D002737ChloropreneChloroprene results in decreased expression of NR4A1 mRNA23125180
D004390ChlorpyrifosChlorpyrifos results in decreased expression of NR4A1 mRNA18668222
D003024ClozapineClozapine results in decreased expression of NR4A1 mRNA10987852|1156442
D003024ClozapineClozapine results in increased expression of NR4A1 mRNA10987852|1969524
C018021cobaltous chloridecobaltous chloride results in decreased expression of NR4A1 mRNA24612858
D003042CocaineCocaine affects the expression of NR4A1 mRNA12358776|1785153
D003042CocaineCocaine results in increased expression of NR4A1 mRNA12117546
D005576ColforsinNR4A1 protein inhibits the reaction [Colforsin results in increased expression of CYP19A1 mRNA]19822197
D005576Colforsin[Colforsin co-treated with deoxynivalenol] results in increased expression of NR4A1 mRNA26783879
D005576ColforsinColforsin promotes the reaction [Zearalenone results in increased expression of NR4A1 mRNA]26783879
D005576ColforsinColforsin results in increased expression of NR4A1 mRNA23183170|8164692
D005576ColforsinColforsin results in increased expression of NR4A1 protein23183170
D005576ColforsinNR4A1 protein inhibits the reaction [Ryanodine inhibits the reaction [Colforsin results in increased expression of STAR protein]]23183170
D005576ColforsinRyanodine inhibits the reaction [Colforsin results in increased expression of NR4A1 mRNA]23183170
D005576ColforsinRyanodine inhibits the reaction [Colforsin results in increased expression of NR4A1 protein]23183170
D005576ColforsinW 7 inhibits the reaction [Colforsin results in increased expression of NR4A1 mRNA]23183170
D005576ColforsinW 7 inhibits the reaction [Colforsin results in increased expression of NR4A1 protein]23183170
D003300CopperCopper results in increased expression of NR4A1 mRNA19747488
D019327Copper SulfateCopper Sulfate results in increased expression of NR4A1 mRNA19549813
C030973cupric oxidecupric oxide results in increased expression of NR4A1 mRNA22077320
C030973cupric oxidecupric oxide results in increased expression of NR4A1 protein22077320
C030973cupric oxideNR4A1 protein results in decreased susceptibility to cupric oxide22077320
D003471CuprizoneCuprizone results in decreased expression of NR4A1 mRNA26577399
D003513CycloheximideCycloheximide promotes the reaction [LHB protein results in increased expression of NR4A1 mRNA]11416027
D016572CyclosporineCyclosporine inhibits the reaction [cadmium acetate results in increased expression of NR4A1 protein]15016657
D016572CyclosporineCyclosporine inhibits the reaction [Antigen-Antibody Complex results in increased expression of NR4A1 mRNA]25451590
C089595cylindrospermopsincylindrospermopsin results in increased expression of NR4A1 mRNA24921660
C004742daidzein[daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of NR4A1 mRNA27424125
C013908daidzin[daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of NR4A1 mRNA27424125
D003622DapsoneDapsone analog inhibits the reaction [Metribolone results in increased expression of NR4A1 mRNA]21440447
C010902decabromobiphenyl etherdecabromobiphenyl ether results in increased expression of NR4A1 mRNA24317228
D013759DronabinolDronabinol results in increased expression of NR4A1 mRNA21955143
C007262deoxynivalenol[Colforsin co-treated with deoxynivalenol] results in increased expression of NR4A1 mRNA26783879
C007262deoxynivalenoldeoxynivalenol results in increased expression of NR4A1 mRNA15371230
D003907DexamethasoneDexamethasone inhibits the reaction [RX3 gene mutant form affects the expression of NR4A1 mRNA]27941970
D003907DexamethasoneDexamethasone inhibits the reaction [Pentylenetetrazole results in increased expression of NR4A1 mRNA]8164692
D003907DexamethasoneDexamethasone affects the localization of NR4A1 protein16403471
C438269diazepinylbenzoic acidNR4A1 affects the susceptibility to diazepinylbenzoic acid15450789
D003993Dibutyl PhthalateDibutyl Phthalate results in increased expression of NR4A1 mRNA17361019|2126653
D003993Dibutyl PhthalateDibutyl Phthalate results in increased expression of NR4A1 mRNA21266533|2174549
D003994BucladesineBucladesine results in increased expression of NR4A1 protein18787026|1928238
D003994BucladesineNR0B1 protein inhibits the reaction [Bucladesine results in increased expression of NR4A1 protein]18787026
D003994BucladesineNR0B1 protein inhibits the reaction [NR4A1 protein promotes the reaction [Bucladesine results in increased expression of STAR mRNA]]18787026
D003994BucladesineNR4A1 protein promotes the reaction [Bucladesine results in increased expression of STAR mRNA]18787026
D003994BucladesineNR4A1 protein promotes the reaction [Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased expression of STAR mRNA]]19282384
D003994BucladesineTetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased expression of NR4A1 protein]19282384
D002945Cisplatin[Cisplatin co-treated with jinfukang] results in increased expression of NR4A1 mRNA27392435
D002945CisplatinCisplatin results in increased expression of NR4A1 mRNA24280081|2739243
D002945CisplatinNR4A1 protein affects the susceptibility to Cisplatin16217747
D002945CisplatinCisplatin results in increased expression of NR4A1 mRNA24280081
D003633Dichlorodiphenyl DichloroethyleneDichlorodiphenyl Dichloroethylene results in increased activity of NR4A1 protein27589886
C000944dicrotophosdicrotophos results in increased expression of NR4A1 mRNA28302478
D004041Dietary FatsDietary Fats affects the expression of NR4A1 mRNA19680557
D019422Dietary SucroseDietary Sucrose results in increased expression of NR4A1 mRNA26033743
D004051Diethylhexyl PhthalateDiethylhexyl Phthalate results in decreased expression of NR4A1 mRNA28085963
D004051Diethylhexyl PhthalateDiethylhexyl Phthalate results in increased expression of NR4A1 mRNA15728792
D002117CalcitriolCalcitriol results in increased expression of NR4A1 mRNA21592394
D002117Calcitriol[Testosterone co-treated with Calcitriol] results in increased expression of NR4A1 mRNA21592394
D0151279,10-Dimethyl-1,2-benzanthracene"[CYP1B1 protein affects the susceptibility to 9,10-Dimethyl-1,2-benzanthracene] which affects the expression of NR4A1 mRNA"27891153
D004128DimethylnitrosamineDimethylnitrosamine results in increased expression of NR4A1 mRNA17032414
C051904dinophysistoxin 1dinophysistoxin 1 results in increased expression of NR4A1 mRNA28939011
C034171di-n-pentyl phthalatedi-n-pentyl phthalate results in increased expression of NR4A1 mRNA15728792
D004281Docosahexaenoic AcidsNR4A1 affects the susceptibility to Docosahexaenoic Acids15450789
D004317DoxorubicinDoxorubicin affects the expression of NR4A1 mRNA15205334
D004317DoxorubicinNR4A1 mRNA results in decreased susceptibility to Doxorubicin16322897
D004317DoxorubicinDoxorubicin results in increased expression of NR4A1 mRNA21040762
D004317Doxorubicin[[MT1 protein co-treated with MT2 protein] affects the susceptibility to Doxorubicin] which affects the expression of NR4A1 mRNA21040762
C045651epigallocatechin gallate[potassium chromate(VI) co-treated with epigallocatechin gallate] results in increased expression of NR4A1 mRNA22079256
D000431EthanolEthanol results in decreased expression of NR4A1 mRNA29018328
D000431EthanolEthanol results in increased expression of NR4A1 mRNA21955143
D004997Ethinyl EstradiolEthinyl Estradiol affects the expression of NR4A1 mRNA17555576
D004997Ethinyl EstradiolEthinyl Estradiol results in increased expression of NR4A1 mRNA17942748
D015025ZearalenoneColforsin promotes the reaction [Zearalenone results in increased expression of NR4A1 mRNA]26783879
D015025ZearalenoneZearalenone results in decreased expression of NR4A1 protein24512812
D015025ZearalenoneZearalenone results in increased expression of NR4A1 mRNA26783879
D011345FenofibrateFenofibrate inhibits the reaction [NR4A1 protein results in increased expression of SERPINE1 mRNA]19593819
D011345FenofibrateNR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [NR4A1 protein results in increased expression of SERPINE1 mRNA]]19593819
D005284FenthionFenthion results in increased expression of NR4A121538558
C007738fluoranthene[1-methylanthracene co-treated with fluoranthene] results in increased expression of NR4A1 mRNA28329830
C007738fluorantheneSB 203580 inhibits the reaction [[1-methylanthracene co-treated with fluoranthene] results in increased expression of NR4A1 mRNA]28329830
D005472FluorouracilFluorouracil affects the expression of NR4A1 mRNA15205334|1655759
D005557FormaldehydeFormaldehyde results in increased expression of NR4A1 mRNA28937961
C070081fulvestrantfulvestrant results in increased expression of NR4A1 mRNA16514628
C039281furanfuran results in increased methylation of NR4A1 gene22079235
D019833Genistein[daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of NR4A1 mRNA27424125
D019833GenisteinGenistein results in decreased expression of NR4A1 mRNA16705744
D019833GenisteinGenistein results in increased expression of NR4A1 mRNA23019147
C040641genistin[daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of NR4A1 mRNA27424125
D019298Glucose-6-Phosphate[Glycerol co-treated with Succinic Acid co-treated with Glucose-6-Phosphate co-treated with Pantothenic Acid co-treated with Niacinamide] results in increased expression of NR4A1 mRNA20505214
C424943glutamyl-Se-methylselenocysteineglutamyl-Se-methylselenocysteine results in decreased expression of NR4A1 mRNA11306469
D005978GlutathioneGlutathione inhibits the reaction [NR4A1 protein affects the cleavage of ATF4 protein]24515801
D005978GlutathioneGlutathione inhibits the reaction [NR4A1 protein affects the cleavage of CASP7 protein]24515801
D005978GlutathioneGlutathione inhibits the reaction [NR4A1 protein affects the cleavage of CASP8 protein]24515801
D005978GlutathioneGlutathione inhibits the reaction [NR4A1 protein affects the cleavage of PARP protein]24515801
D005978GlutathioneGlutathione inhibits the reaction [NR4A1 protein affects the expression of DDIT3 protein]24515801
D005978GlutathioneGlutathione inhibits the reaction [NR4A1 protein affects the expression of SESN2 protein]26035713
D005978GlutathioneGlutathione inhibits the reaction [NR4A1 protein affects the expression of XBP1 protein alternative form]24515801
D005978GlutathioneGlutathione inhibits the reaction [NR4A1 protein affects the phosphorylation of EIF2AK3 protein]24515801
D005990Glycerol[Glycerol co-treated with Succinic Acid co-treated with Glucose-6-Phosphate co-treated with Pantothenic Acid co-treated with Niacinamide] results in increased expression of NR4A1 mRNA20505214
C004312glycidolglycidol results in decreased expression of NR4A1 mRNA24915197
C086566glycitein[daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of NR4A1 mRNA27424125
C433283glycitin[daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of NR4A1 mRNA27424125
D006046Gold[Gold co-treated with Polyethylene Glycols] results in increased expression of NR4A1 mRNA19695318
D006064Gonadotropins, Equine"Gonadotropins, Equine results in decreased expression of NR4A1 mRNA"11416027
D006220HaloperidolNR4A1 affects the susceptibility to Haloperidol14603264
D006220Haloperidol8-Hydroxy-2-(di-n-propylamino)tetralin inhibits the reaction [Haloperidol results in increased expression of NR4A1 mRNA]19695244
D006220HaloperidolHaloperidol results in decreased expression of NR4A1 mRNA11564422
D006220HaloperidolHaloperidol results in increased expression of NR4A1 mRNA10987852|1969524
D006063Chorionic GonadotropinChorionic Gonadotropin inhibits the reaction [Pentobarbital results in decreased expression of NR4A1 mRNA]11416027
D006063Chorionic GonadotropinChorionic Gonadotropin results in increased expression of NR4A1 mRNA11416027
C000625835HFPO2 compoundHFPO2 compound results in decreased expression of NR4A1 mRNA27553808
C000625836HFPO4 compoundHFPO4 compound results in decreased expression of NR4A1 mRNA27553808
D017313FenretinideFenretinide affects the localization of NR4A1 protein21319187
D017313Fenretinide[Fenretinide co-treated with scriptaid] affects the localization of NR4A1 protein21319187
D017313Fenretinide[Fenretinide co-treated with trichostatin A] affects the localization of NR4A1 protein21319187
D017313FenretinideFenretinide promotes the reaction [scriptaid results in increased expression of NR4A1 mRNA]21319187
D017313FenretinideFenretinide promotes the reaction [scriptaid results in increased expression of NR4A1 protein]21319187
D017313FenretinideFenretinide promotes the reaction [trichostatin A results in increased expression of NR4A1 mRNA]21319187
D017313FenretinideFenretinide promotes the reaction [trichostatin A results in increased expression of NR4A1 protein]21319187
D017313FenretinideFenretinide results in increased expression of NR4A1 mRNA19912993|2131918
D017313FenretinideFenretinide results in increased expression of NR4A1 protein21319187
D017313FenretinideNR4A1 protein affects the reaction [Fenretinide results in increased expression of CASP3 protein modified form]19912993
D017313FenretinideNR4A1 protein affects the susceptibility to Fenretinide19912993
D017313FenretinideNR4A1 protein promotes the reaction [Fenretinide results in increased cleavage of CASP3 protein]21319187
D017313FenretinideRARB protein promotes the reaction [Fenretinide promotes the reaction [scriptaid results in increased expression of NR4A1 protein]]21319187
D017313FenretinideRARB protein promotes the reaction [Fenretinide promotes the reaction [trichostatin A results in increased expression of NR4A1 protein]]21319187
D017313FenretinideRARB protein promotes the reaction [Fenretinide results in increased expression of NR4A1 protein]21319187
D017313Fenretinidetrichostatin A promotes the reaction [Fenretinide results in increased expression of NR4A1 mRNA]21319187
C503536HS-1199HS-1199 results in increased localization of NR4A1 protein15033715
C479128HS 1200HS 1200 results in increased localization of NR4A1 protein15033715
D006861Hydrogen PeroxideHydrogen Peroxide results in decreased expression of NR4A1 mRNA26846883
D006861Hydrogen PeroxideHydrogen Peroxide affects the expression of NR4A1 mRNA20044591
D006861Hydrogen PeroxideHydrogen Peroxide results in increased expression of NR4A1 mRNA12414654
D007051Ibotenic AcidAmphetamine promotes the reaction [Ibotenic Acid results in decreased expression of NR4A1 mRNA]14622910
D007051Ibotenic AcidIbotenic Acid results in decreased expression of NR4A1 mRNA14622910
C016517indole-3-carbinolindole-3-carbinol affects the expression of NR4A1 mRNA21396975
D007213IndomethacinIndomethacin results in increased expression of and results in increased activity of NR4A1 protein10919358
D007213IndomethacinIndomethacin results in increased expression of NR4A1 mRNA10919358
D007213IndomethacinTretinoin inhibits the reaction [Indomethacin results in increased expression of NR4A1 mRNA]10919358
D015759Ionomycin[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of NR4A1 mRNA25613284
D007545IsoproterenolIsoproterenol results in decreased expression of NR4A1 mRNA20003209
C544151jinfukang[Cisplatin co-treated with jinfukang] results in increased expression of NR4A1 mRNA27392435
C098607JP8 aviation fuelJP8 aviation fuel results in decreased expression of NR4A1 mRNA15618438
C098607JP8 aviation fuelJP8 aviation fuel results in increased expression of NR4A1 protein17337753
C561695(+)-JQ1 compound(+)-JQ1 compound results in decreased expression of NR4A1 mRNA23086925
C561695(+)-JQ1 compound(+)-JQ1 compound inhibits the reaction [BDNF protein promotes the reaction [BRD4 protein binds to NR4A1 promoter]]26301327
C561695(+)-JQ1 compound(+)-JQ1 compound inhibits the reaction [BDNF protein results in increased expression of NR4A1 mRNA]26301327
C561695(+)-JQ1 compound(+)-JQ1 compound results in decreased expression of NR4A1 mRNA26301327
D007608Kainic AcidKainic Acid results in decreased expression of NR4A1 mRNA17997037
D007608Kainic AcidKainic Acid results in increased expression of NR4A1 mRNA19700661
C119620kenpaullonekenpaullone results in increased expression of NR4A1 mRNA17993264
D020910KetorolacKetorolac inhibits the reaction [IL1B protein results in increased expression of NR4A1 mRNA]10800959
C008261lead acetatelead acetate results in decreased expression of NR4A1 mRNA22641619
C031895lead chromatelead chromate results in increased expression of NR4A1 mRNA23584427
C045463leflunomideleflunomide results in increased expression of NR4A1 mRNA28988120
C038753leptomycin Bleptomycin B inhibits the reaction [Tretinoin affects the localization of [NR4A1 protein binds to RXRA protein]]14592536
C002385linsidominelinsidomine results in increased expression of NR4A1 mRNA10460269
D008070LipopolysaccharidesLipopolysaccharides results in decreased expression of NR4A1 mRNA27339419
D008070Lipopolysaccharides[Lipopolysaccharides co-treated with Ranitidine] results in increased expression of NR4A1 mRNA16415329
D008344Maneb[Paraquat co-treated with Maneb] affects the expression of NR4A1 mRNA22563483
D008628MercuryMercury results in decreased expression of NR4A1 mRNA12730625
C527236metacept-1[metacept-1 co-treated with Azacitidine] results in increased expression of NR4A119148494
D008694MethamphetamineMethamphetamine results in increased expression of NR4A1 mRNA15644446
C005219methyl cellosolvemethyl cellosolve results in increased expression of NR4A1 mRNA19643169
D008748MethylcholanthreneMethylcholanthrene results in decreased expression of NR4A1 mRNA20713471
C004925methylmercuric chloridemethylmercuric chloride results in increased expression of NR4A1 mRNA23103053
C004925methylmercuric chloridemethylmercuric chloride results in increased expression of NR4A1 mRNA28001369
D018817N-Methyl-3,4-methylenedioxyamphetamine"N-Methyl-3,4-methylenedioxyamphetamine results in decreased expression of NR4A1 mRNA"20188158
D0156551-Methyl-4-phenylpyridinium1-Methyl-4-phenylpyridinium results in increased expression of NR4A1 mRNA24810058
D015741MetriboloneDapsone analog inhibits the reaction [Metribolone results in increased expression of NR4A1 mRNA]21440447
D015741MetriboloneMetribolone results in increased expression of NR4A1 mRNA21440447
C016599mono-(2-ethylhexyl)phthalatemono-(2-ethylhexyl)phthalate results in decreased expression of NR4A1 mRNA23118965
C016599mono-(2-ethylhexyl)phthalatemono-(2-ethylhexyl)phthalate results in increased expression of NR4A1 mRNA19822197
C016599mono-(2-ethylhexyl)phthalatemono-(2-ethylhexyl)phthalate results in decreased expression of NR4A1 mRNA22401849
D009020MorphineMorphine results in increased expression of NR4A1 mRNA21955143
C500085muraglitazarmuraglitazar results in decreased expression of NR4A1 mRNA21515302
C583365N-(2-(1,1'-bicyclopropyl)-2-ylphenyl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide"N-(2-(1,1'-bicyclopropyl)-2-ylphenyl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide results in increased expression of NR4A1 mRNA"29244179
C518313N-((2,2-dimethyl-2,3-dihydrobenzofuran-7-yloxy)ethyl)-3-(cyclopent-1-enyl)benzylamine"N-((2,2-dimethyl-2,3-dihydrobenzofuran-7-yloxy)ethyl)-3-(cyclopent-1-enyl)benzylamine results in increased expression of NR4A1 mRNA"19695244
C090413N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl)cyclohexanecarboxamideN-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl)cyclohexanecarboxamide results in increased expression of NR4A1 mRNA19695244
C063509N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamideN-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [cadmium acetate results in increased expression of NR4A1 protein]15016657
C063509N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamideN-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [bisphenol A results in increased expression of NR4A1 mRNA]12021184
D037742Nanotubes, Carbon"Nanotubes, Carbon results in decreased expression of NR4A1 mRNA"25554681|2562005
D009281NaphthalenesNaphthalenes results in increased expression of NR4A1 protein17337753
C017096n-butoxyethanoln-butoxyethanol results in increased expression of NR4A1 mRNA19812364
D009532NickelNickel results in increased expression of NR4A1 mRNA12540486
C022838nickel chloridenickel chloride results in decreased expression of NR4A1 mRNA24612858
C029938nickel sulfatenickel sulfate results in increased expression of NR4A1 mRNA16780908
D009538NicotineNicotine results in decreased expression of NR4A1 mRNA21955143
D009538NicotineNicotine results in increased expression of NR4A1 mRNA17456735
D009569Nitric OxideNitric Oxide results in increased expression of NR4A1 mRNA10460269
D020030Nitric Oxide DonorsNitric Oxide Donors results in increased expression of NR4A1 mRNA10460269
C014707nitrosobenzylmethylaminenitrosobenzylmethylamine results in increased expression of NR4A1 mRNA17616710
D0173718-Hydroxy-2-(di-n-propylamino)tetralin8-Hydroxy-2-(di-n-propylamino)tetralin inhibits the reaction [Haloperidol results in increased expression of NR4A1 mRNA]19695244
C030110oxaliplatin[oxaliplatin co-treated with Topotecan] results in increased expression of NR4A1 mRNA25729387
C030110oxaliplatinoxaliplatin results in increased expression of NR4A1 mRNA25729387
D010126Ozonepyrazolanthrone promotes the reaction [Ozone results in increased expression of NR4A1 mRNA]17460151
D010126Ozone[Ozone co-treated with Chlorine] affects the expression of NR4A1 mRNA18636392
D010126OzoneOzone results in increased expression of NR4A1 mRNA16716893
D000073878Palm OilPalm Oil affects the expression of NR4A1 mRNA19680557
D010269Paraquat[Paraquat co-treated with Maneb] affects the expression of NR4A1 mRNA22563483
D010269ParaquatParaquat results in decreased expression of NR4A1 mRNA22563483
D010269ParaquatParaquat results in increased expression of NR4A1 mRNA12595580
C084656paricalcitol[Phosphorus co-treated with paricalcitol] affects the expression of NR4A1 mRNA17715259
D052638Particulate MatterParticulate Matter results in decreased expression of NR4A1 mRNA22178795
C000610380p-carboxymethylphenyl 1,1-bis(3'-indolyl)-1-(p-carboxymethylphenyl)methane"NR4A1 protein results in increased susceptibility to p-carboxymethylphenyl 1,1-bis(3'-indolyl)-1-(p-carboxymethylphenyl)methane"26035713|2692920
C000610380p-carboxymethylphenyl 1,1-bis(3'-indolyl)-1-(p-carboxymethylphenyl)methane"p-carboxymethylphenyl 1,1-bis(3'-indolyl)-1-(p-carboxymethylphenyl)methane inhibits the reaction [TGFB1 protein affects the localization of NR4A1 protein]"26929200
C000610380p-carboxymethylphenyl 1,1-bis(3'-indolyl)-1-(p-carboxymethylphenyl)methane"p-carboxymethylphenyl 1,1-bis(3'-indolyl)-1-(p-carboxymethylphenyl)methane inhibits the reaction [TGFB1 protein promotes the reaction [NR4A1 protein binds to AXIN2 protein]]"26929200
C568608PCI 5002[PCI 5002 co-treated with Zinc] results in increased expression of NR4A1 mRNA18593933
D010396PenicillaminePenicillamine results in increased expression of NR4A1 mRNA19575532
C086401pentabromodiphenyl etherpentabromodiphenyl ether analog results in increased expression of NR4A1 mRNA19095052
D010424PentobarbitalChorionic Gonadotropin inhibits the reaction [Pentobarbital results in decreased expression of NR4A1 mRNA]11416027
D010424PentobarbitalPentobarbital results in decreased expression of NR4A1 mRNA11416027
D010433PentylenetetrazoleDexamethasone inhibits the reaction [Pentylenetetrazole results in increased expression of NR4A1 mRNA]8164692
D010433PentylenetetrazolePentylenetetrazole results in increased expression of NR4A1 mRNA8164692
C023036perfluorooctanoic acidperfluorooctanoic acid results in decreased expression of NR4A1 mRNA19162173
D010575PesticidesPesticides results in increased expression of NR4A121538558
D010634PhenobarbitalPhenobarbital results in decreased expression of NR4A1 mRNA19270015
D010758Phosphorus[Phosphorus co-treated with paricalcitol] affects the expression of NR4A1 mRNA17715259
C060836pioglitazonepioglitazone results in increased expression of NR4A1 mRNA17785466
D010938Plant OilsPlant Oils results in increased expression of NR4A1 mRNA23370395
D011092Polyethylene Glycols[Gold co-treated with Polyethylene Glycols] results in increased expression of NR4A1 mRNA19695318
D011188PotassiumPotassium results in increased expression of NR4A1 mRNA10693946
C027373potassium chromate(VI)[potassium chromate(VI) co-treated with epigallocatechin gallate] results in increased expression of NR4A1 mRNA22079256
C027373potassium chromate(VI)potassium chromate(VI) results in increased expression of NR4A1 mRNA22079256
D011285Pregnenolone CarbonitrilePregnenolone Carbonitrile results in decreased expression of NR4A1 mRNA22698814
D011285Pregnenolone CarbonitrilePregnenolone Carbonitrile results in increased expression of NR4A1 mRNA19162173
D044945ProanthocyanidinsProanthocyanidins inhibits the reaction [quinocetone metabolite affects the expression of NR4A1 mRNA]26802905
D011374ProgesteroneProgesterone results in increased expression of NR4A1 mRNA18037150
D011374ProgesteroneNR4A1 protein mutant form inhibits the reaction [bisphenol A results in increased abundance of Progesterone]12021184
D011374Progesterone"NR4A1 protein promotes the reaction [2,2-bis(4-glycidyloxyphenyl)propane affects the abundance of Progesterone]"18525235
D011374ProgesteroneNR4A1 protein promotes the reaction [bisphenol A results in increased abundance of Progesterone]12021184
C010313pseudocumenepseudocumene results in increased expression of NR4A1 protein17337753
C432165pyrazolanthronepyrazolanthrone promotes the reaction [Ozone results in increased expression of NR4A1 mRNA]17460151
C428725pyridabenpyridaben results in decreased expression of NR4A1 mRNA22563483
D011794QuercetinQuercetin results in increased expression of NR4A1 mRNA21632981
D011794QuercetinQuercetin results in decreased expression of NR4A1 mRNA25862958
C502851quinocetoneProanthocyanidins inhibits the reaction [quinocetone metabolite affects the expression of NR4A1 mRNA]26802905
C502851quinocetonequinocetone metabolite affects the expression of NR4A1 mRNA26802905
D020891RacloprideNR4A1 affects the susceptibility to Raclopride14603264
D020849Raloxifene HydrochlorideRaloxifene Hydrochloride results in increased expression of NR4A1 mRNA16514628
D011899Ranitidine[Lipopolysaccharides co-treated with Ranitidine] results in increased expression of NR4A1 mRNA16415329
D017382Reactive Oxygen SpeciesReactive Oxygen Species affects the expression of NR4A1 mRNA25800948
C052785rebamipiderebamipide results in increased expression of NR4A1 mRNA15104358
C089730rosiglitazonerosiglitazone results in decreased expression of NR4A1 mRNA21515302
D012433RyanodineNR4A1 protein inhibits the reaction [Ryanodine inhibits the reaction [Colforsin results in increased expression of STAR protein]]23183170
D012433RyanodineRyanodine inhibits the reaction [Colforsin results in increased expression of NR4A1 mRNA]23183170
D012433RyanodineRyanodine inhibits the reaction [Colforsin results in increased expression of NR4A1 protein]23183170
C093642SB 203580SB 203580 inhibits the reaction [[1-methylanthracene co-treated with fluoranthene] results in increased expression of NR4A1 mRNA]28329830
D012601Scopolamine HydrobromideScopolamine Hydrobromide results in decreased expression of NR4A1 mRNA17540011
C410733scriptaid[Fenretinide co-treated with scriptaid] affects the localization of NR4A1 protein21319187
C410733scriptaidFenretinide promotes the reaction [scriptaid results in increased expression of NR4A1 mRNA]21319187
C410733scriptaidFenretinide promotes the reaction [scriptaid results in increased expression of NR4A1 protein]21319187
C410733scriptaidNR4A1 protein promotes the reaction [scriptaid results in increased cleavage of CASP3 protein]21319187
C410733scriptaidRARB protein promotes the reaction [Fenretinide promotes the reaction [scriptaid results in increased expression of NR4A1 protein]]21319187
C410733scriptaidRARB protein promotes the reaction [scriptaid results in increased expression of NR4A1 protein]21319187
C410733scriptaidscriptaid affects the localization of NR4A1 protein21319187
C410733scriptaidscriptaid results in increased expression of NR4A1 mRNA21319187
C410733scriptaidscriptaid results in increased expression of NR4A1 protein21319187
C009250sevofluranesevoflurane affects the expression of NR4A1 mRNA15967596
C016101shikoninshikonin inhibits the reaction [Antigen-Antibody Complex results in increased expression of NR4A1 mRNA]25451590
C016101shikoninshikonin inhibits the reaction [Calcimycin results in increased expression of NR4A1 mRNA]25451590
D012822Silicon DioxideSilicon Dioxide analog results in increased expression of NR4A1 mRNA23806026
D012822Silicon DioxideSilicon Dioxide results in increased expression of NR4A1 mRNA19073995|2322117
D012834SilverSilver results in increased expression of NR4A1 mRNA26014281|2895954
D012834SilverSilver results in increased expression of NR4A1 mRNA27131904
D012906SmokeSmoke results in increased expression of NR4A1 protein20015449
C009277sodium arsenatesodium arsenate results in decreased expression of NR4A1 mRNA21795629
C017947sodium arsenitesodium arsenite results in increased expression of NR4A1 mRNA12760830
C017947sodium arsenitesodium arsenite results in increased expression of NR4A1 mRNA16014739
C017947sodium arsenitesodium arsenite results in increased expression of NR4A1 protein17682005
C016104sodium bichromatesodium bichromate results in decreased expression of NR4A1 mRNA24612858
C016104sodium bichromatesodium bichromate results in increased expression of NR4A1 mRNA27859739
D012999SomanSoman results in increased expression of NR4A1 mRNA19281266
D053260SootSoot affects the expression of NR4A1 mRNA26551751
C041711St. Thomas' Hospital cardioplegic solutionSt. Thomas' Hospital cardioplegic solution results in decreased expression of NR4A1 mRNA16214533
D020058StyreneStyrene affects the expression of NR4A1 mRNA28951217
D019802Succinic Acid[Glycerol co-treated with Succinic Acid co-treated with Glucose-6-Phosphate co-treated with Pantothenic Acid co-treated with Niacinamide] results in increased expression of NR4A1 mRNA20505214
D014284Triiodothyronine"2,2',4,4'-tetrahydroxybenzophenone inhibits the reaction [Triiodothyronine inhibits the reaction [[NR4A1 co-treated with THRA] results in increased expression of HSD3B1 mRNA]]"21726595
D014284Triiodothyronine"2,2',4,4'-tetrahydroxybenzophenone inhibits the reaction [Triiodothyronine inhibits the reaction [[NR4A1 co-treated with THRA] results in increased expression of STAR mRNA]]"21726595
D014284Triiodothyronine"2,2',4,4'-tetrahydroxybenzophenone inhibits the reaction [Triiodothyronine promotes the reaction [[NR4A1 co-treated with THRA] results in increased expression of HSD3B1 mRNA]]"21726595
D014284TriiodothyronineTriiodothyronine inhibits the reaction [[NR4A1 co-treated with THRA] results in increased expression of HSD3B1 mRNA]21726595
D014284TriiodothyronineTriiodothyronine inhibits the reaction [[NR4A1 co-treated with THRA] results in increased expression of STAR mRNA]21726595
D014284TriiodothyronineTriiodothyronine promotes the reaction [[NR4A1 co-treated with THRA] results in increased expression of HSD3B1 mRNA]21726595
C013698tallowtallow affects the expression of NR4A1 mRNA19680557
D013629TamoxifenTamoxifen affects the expression of NR4A1 mRNA17555576
C012568terbufosterbufos results in increased expression of NR4A121538558
D013739Testosterone[Testosterone co-treated with Calcitriol] results in increased expression of NR4A1 mRNA21592394
D013739TestosteroneTestosterone results in increased expression of NR4A1 mRNA21592394
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of NR4A1 mRNA26238291
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of NR4A1 mRNA16962184|2405805
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased expression of NR4A1 mRNA26290441
D013755Tetradecanoylphorbol AcetateTetradecanoylphorbol Acetate affects the localization of NR4A1 protein12376465|2875443
D013755Tetradecanoylphorbol AcetateTetradecanoylphorbol Acetate results in increased expression of NR4A1 mRNA12376465
D013755Tetradecanoylphorbol Acetate[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of NR4A1 mRNA16979875
D013755Tetradecanoylphorbol Acetatebisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NR4A1 protein]19282384
D013755Tetradecanoylphorbol AcetateNR0B1 protein inhibits the reaction [NR4A1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of STAR mRNA]]18787026
D013755Tetradecanoylphorbol AcetateNR0B1 protein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NR4A1 protein]18787026
D013755Tetradecanoylphorbol AcetateNR4A1 protein promotes the reaction [Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased expression of STAR mRNA]]19282384
D013755Tetradecanoylphorbol AcetateNR4A1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of STAR mRNA]18787026|1928238
D013755Tetradecanoylphorbol AcetateTetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased expression of NR4A1 protein]19282384
D013755Tetradecanoylphorbol AcetateTetradecanoylphorbol Acetate results in increased expression of NR4A1 protein18787026|1928238
D013755Tetradecanoylphorbol Acetate[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of NR4A1 mRNA25613284
D013792ThalidomideThalidomide analog results in increased expression of NR4A1 mRNA20525221
D013849ThimerosalThimerosal results in increased expression of NR4A1 mRNA16870260
D013853ThioacetamideThioacetamide results in increased expression of NR4A1 mRNA23411599
C009495titanium dioxidetitanium dioxide results in decreased expression of NR4A1 mRNA27760801
C009495titanium dioxidetitanium dioxide results in increased expression of NR4A1 mRNA23557971
D014028Tobacco Smoke PollutionTobacco Smoke Pollution affects the expression of NR4A1 mRNA20133372
D019772Topotecan[oxaliplatin co-treated with Topotecan] results in increased expression of NR4A1 mRNA25729387
C483909torcetrapibtorcetrapib results in increased expression of NR4A1 mRNA19164467|2322803
D014212Tretinoinleptomycin B inhibits the reaction [Tretinoin affects the localization of [NR4A1 protein binds to RXRA protein]]14592536
D014212TretinoinTretinoin affects the localization of [NR4A1 protein binds to RXRA protein]14592536
D014212TretinoinTretinoin inhibits the reaction [Indomethacin results in increased expression of NR4A1 mRNA]10919358
D014212TretinoinTretinoin results in decreased expression of NR4A1 mRNA23830798
D014212TretinoinTretinoin results in increased activity of [NR4A1 protein binds to RXRA protein]14592536
D014229TriazolamTriazolam results in decreased expression of NR4A1 mRNA27489535
C012589trichostatin A[Fenretinide co-treated with trichostatin A] affects the localization of NR4A1 protein21319187
C012589trichostatin AFenretinide promotes the reaction [trichostatin A results in increased expression of NR4A1 mRNA]21319187
C012589trichostatin AFenretinide promotes the reaction [trichostatin A results in increased expression of NR4A1 protein]21319187
C012589trichostatin ANR4A1 protein promotes the reaction [trichostatin A results in increased cleavage of CASP3 protein]21319187
C012589trichostatin ARARB protein promotes the reaction [Fenretinide promotes the reaction [trichostatin A results in increased expression of NR4A1 protein]]21319187
C012589trichostatin ARARB protein promotes the reaction [trichostatin A results in increased expression of NR4A1 protein]21319187
C012589trichostatin Atrichostatin A affects the localization of NR4A1 protein21319187
C012589trichostatin Atrichostatin A promotes the reaction [Fenretinide results in increased expression of NR4A1 mRNA]21319187
C012589trichostatin Atrichostatin A results in increased expression of NR4A1 mRNA21319187
C012589trichostatin Atrichostatin A results in increased expression of NR4A1 protein21319187
C013320tris(2-butoxyethyl) phosphatetris(2-butoxyethyl) phosphate affects the expression of NR4A1 mRNA29024780
C057693troglitazonetroglitazone results in increased expression of NR4A1 mRNA17785466
C057693troglitazonetroglitazone results in decreased expression of NR4A1 mRNA21515302
C022884undecaneundecane results in increased expression of NR4A1 protein17337753
D014520UrethaneUrethane results in increased expression of NR4A1 mRNA28818685
C025643vinclozolinvinclozolin affects the expression of NR4A1 mRNA19015723
D014800VitalliumVitallium analog results in increased expression of NR4A1 mRNA23825117
D009536Niacinamide[Glycerol co-treated with Succinic Acid co-treated with Glucose-6-Phosphate co-treated with Pantothenic Acid co-treated with Niacinamide] results in increased expression of NR4A1 mRNA20505214
D010205Pantothenic Acid[Glycerol co-treated with Succinic Acid co-treated with Glucose-6-Phosphate co-treated with Pantothenic Acid co-treated with Niacinamide] results in increased expression of NR4A1 mRNA20505214
D024483Vitamin K 3Vitamin K 3 affects the expression of NR4A1 mRNA20044591
D024483Vitamin K 3Vitamin K 3 results in increased expression of NR4A1 mRNA12414654
C017967W 7W 7 inhibits the reaction [Colforsin results in increased expression of NR4A1 mRNA]23183170
C017967W 7W 7 inhibits the reaction [Colforsin results in increased expression of NR4A1 protein]23183170
D014874Water Pollutants, Chemical"Water Pollutants, Chemical results in decreased expression of NR4A1 mRNA"24525044
D015032Zinc[PCI 5002 co-treated with Zinc] results in increased expression of NR4A1 mRNA18593933
D015032Zinc[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of NR4A1 mRNA16979875
D015032ZincZinc deficiency results in increased expression of NR4A1 mRNA18356318

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0000977RNA polymerase II regulatory region sequence-specific DNA binding-IBA21873635  
GO:0000978RNA polymerase II proximal promoter sequence-specific DNA binding-IBA21873635  
GO:0000981RNA polymerase II transcription factor activity, sequence-specific DNA binding-ISA-  
GO:0000981RNA polymerase II transcription factor activity, sequence-specific DNA binding-ISM19274049  
GO:0000981RNA polymerase II transcription factor activity, sequence-specific DNA binding-NAS19274049  
GO:0001077transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding-IBA21873635  
GO:0001077transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding-ISS-  
GO:0003677DNA binding-ISS-  
GO:0003707steroid hormone receptor activity-IEA-  
GO:0004879nuclear receptor activity-IEA-  
GO:0005515protein binding-IPI17139261  18305892  18835031  18985028  20195357  21988832  
22761572  24139859  25416956  
GO:0008270zinc ion binding-IEA-  
GO:0035259glucocorticoid receptor binding-IBA21873635  
GO:0043565sequence-specific DNA binding-IBA21873635  
GO:0043565sequence-specific DNA binding-IEA-  
GO:0046982protein heterodimerization activity-ISS-  
GO ID GO Term Qualifier Evidence PubMed
GO:0001938positive regulation of endothelial cell proliferation-IMP18059339  
GO:0002042cell migration involved in sprouting angiogenesis-IDA18059339  
GO:0006367transcription initiation from RNA polymerase II promoter-TAS-  
GO:0007165signal transduction-TAS2626032  
GO:0030522intracellular receptor signaling pathway-IEA-  
GO:0035767endothelial cell chemotaxis-IMP18059339  
GO:0035924cellular response to vascular endothelial growth factor stimulus-IMP18059339  
GO:0043401steroid hormone mediated signaling pathway-IEA-  
GO:0044344cellular response to fibroblast growth factor stimulus-IMP18059339  
GO:0045444fat cell differentiation-ISS-  
GO:0045786negative regulation of cell cycle-ISS-  
GO:0045944positive regulation of transcription by RNA polymerase II-IDA22427340  
GO:0061469regulation of type B pancreatic cell proliferation-ISS-  
GO:0071376cellular response to corticotropin-releasing hormone stimulus-IBA21873635  
GO:0071376cellular response to corticotropin-releasing hormone stimulus-ISS-  
GO ID GO Term Qualifier Evidence PubMed
GO:0005634nucleus-IBA21873635  
GO:0005634nucleus-IDA-  
GO:0005634nucleus-ISS-  
GO:0005654nucleoplasm-TAS-  
GO:0005667transcription factor complex-IBA21873635  
GO:0005829cytosol-IDA-  
GO:0031965nuclear membrane-IDA-  
KEGG ID KEGG Term
hsa04010MAPK signaling pathway
Reactome ID Reactome Term Evidence
R-HSA-1257604PIP3 activates AKT signalingTAS
R-HSA-162582Signal TransductionTAS
R-HSA-1643685DiseaseTAS
R-HSA-198693AKT phosphorylates targets in the nucleusTAS
R-HSA-212436Generic Transcription PathwayTAS
R-HSA-2219528PI3K/AKT Signaling in CancerTAS
R-HSA-383280Nuclear Receptor transcription pathwayTAS
R-HSA-5663202Diseases of signal transductionTAS
R-HSA-5674400Constitutive Signaling by AKT1 E17K in CancerTAS
R-HSA-73857RNA Polymerase II TranscriptionTAS
R-HSA-74160Gene expression (Transcription)TAS
R-HSA-9006925Intracellular signaling by second messengersTAS

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
20659174Replicated association of the NR4A3 gene with smoking behaviour in schizophrenia and in bipolar disorder. (2010 Nov)Novak GGenes Brain Behav